Yr Athro Arwyn Jones

2024

• Rizzo, S., Varache, M., Sayers, E. J., Jones, A. T., Tonks, A., Thomas, D. W. and Ferguson, E. L. 2024. Modification of the antibiotic, colistin, with dextrin causes enhanced cytotoxicity and triggers apoptosis in myeloid leukemia. International Journal of Nanomedicine 19, pp. 5419-5437. (10.2147/IJN.S449185)
• Varache, M. et al. 2024. Dextrin conjugation to colistin inhibits its toxicity, cellular uptake and acute kidney injury in vivo. RSC Pharmaceutics 1, pp. 68-79. (10.1039/D3PM00014A)

2023

• Hunter, M. R. et al. 2023. Understanding Intracellular Biology to Improve mRNA Delivery by Lipid Nanoparticles. small methods, article number: 2201695. (10.1002/smtd.202201695)
• Lambourne, O. A. et al. 2023. PINK1-Dependent mitophagy inhibits elevated ubiquitin phosphorylation caused by mitochondrial damage. Journal of Medicinal Chemistry 66(11), pp. 7645-7656. (10.1021/acs.jmedchem.3c00555)
• Birch, D., Sayers, E. J., Christensen, M. V., Jones, A. T., Franzyk, H. and Nielsen, H. M. 2023. Stereoisomer-dependent membrane association and capacity for insulin delivery facilitated by Penetratin. Pharmaceutics 15(6), article number: 1672. (10.3390/pharmaceutics15061672)
• Daniele, R. et al. 2023. Influence of folate-targeted gold nanoparticles on subcellular localization and distribution into lysosomes. Pharmaceutics 15(3), article number: 864. (10.3390/pharmaceutics15030864)

2022

• Griffiths, G., Gruenberg, J., Marsh, M., Wohlmann, J., Jones, A. T. and Parton, R. G. 2022. Nanoparticle entry into cells; the cell biology weak link. Advanced Drug Delivery Reviews 188, article number: 114403. (10.1016/j.addr.2022.114403)
• Allemann, R. K., Samperio, R., Mart, R., Luk, L., Tsai, Y., Jones, A. and Cruz Samperio, R. 2022. Spatio-temporal control of cell death by selective delivery of photo-activatable proteins. ChemBioChem 23(12), article number: e202200115. (10.1002/cbic.202200115)
• Aikman, B. et al. 2022. Highly-fluorescent BODIPY-functionalised metallacages as drug delivery systems: synthesis, characterisation and cellular accumulation studies. Dalton Transactions 51(19), pp. 7476-7490. (10.1039/D2DT00337F)
• Sayers, E. J., Palmer, I., Hope, L., Hope, P., Watson, P. and Jones, A. T. 2022. Fluid-phase endocytosis and lysosomal degradation of bovine lactoferrin in lung cells. Pharmaceutics 14(4), article number: 855. (10.3390/pharmaceutics14040855)
• Sayers, E. J., Barlow, V. L., Tsai, Y. and Jones, A. T. 2022. Quantitative subcellular analysis of cyclic cell-penetrating peptide EJP18 in nonadherent cells. In: Cell Penetrating Peptides., Vol. 2383. Methods in Molecular Biology book series Springer, pp. 211-228., (10.1007/978-1-0716-1752-6_14)
• Gurney, L., Robson, S. C., Sweeney, M., Jones, A. T. and Taggart, M. J. 2022. Strategies for peptide-mediated cargo delivery to human smooth muscle cells. In: Langel, U. ed. Cell Penetrating Peptides., Vol. 2383. Methods in Molecular Biology book series Springer, pp. 459-471., (10.1007/978-1-0716-1752-6_29)

2021

• Padalino, G. et al. 2021. Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation. European Journal of Medicinal Chemistry 226, article number: 113823. (10.1016/j.ejmech.2021.113823)
• Hamdy, R. et al. 2021. New bioactive fused triazolothiadiazoles as Bcl-2-targeted anticancer agents. International Journal of Molecular Sciences 22(22), article number: 12272. (10.3390/ijms222212272)
• Mills, E. M., Barlow, V. L., Jones, A. T. and Tsai, Y. 2021. Development of mammalian cell logic gates controlled by unnatural amino acids. Cell Reports Methods 1(6), article number: 100073. (10.1016/j.crmeth.2021.100073)
• Herkert, E. et al. 2021. Roadmap on bio-nano-photonics. Journal of Optics 23(7), article number: 73001. (10.1088/2040-8986/abff94)

2020

• Hamdy, R., Elseginy, S. A., Ziedan, N. I., El-Sadek, M., Lashin, E., Jones, A. T. and Westwell, A. D. 2020. Design, synthesis and evaluation of new bioactive oxadiazole derivatives as anticancer agents targeting Bcl-2. International Journal of Molecular Sciences 21(23), article number: 8980. (10.3390/ijms21238980)
• Nödling, A. et al. 2020. Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes. Chemical Communications 56(34), pp. 4672-4675. (10.1039/C9CC07931A)
• Wymant, J. M., Sayers, E. J., Muir, D. and Jones, A. T. 2020. Strategic trastuzumab mediated crosslinking driving concomitant HER2 and HER3 endocytosis and degradation in breast cancer. Journal of Cancer 11(11), pp. 3288-3302. (10.7150/jca.32470)
• Giannakopoulou, N. et al. 2020. Four-wave-mixing microscopy reveals non-colocalisation between gold nanoparticles and fluorophore conjugates inside cells. Nanoscale 12(7), pp. 4622-4635. (10.1039/C9NR08512B)
• Eissa, N., Sayers, E., Birch, D., Patel, S., Tsai, Y., Nielsen, H. M. and Jones, A. 2020. EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide. Biochemical Journal 477(1), pp. 45-60. (10.1042/BCJ20190452)

2019

• Sayers, E. J. et al. 2019. Endocytic profiling of cancer cell models reveals critical factors influencing lipid nanoparticle mediated mRNA delivery and protein expression. Molecular Therapy 27(11), pp. 1950-1962. (10.1016/j.ymthe.2019.07.018)
• Woods, B. et al. 2019. Highly luminescent metallacages featuring bispyridyl ligands functionalised with BODIPY for imaging in cancer cells. Journal of Inorganic Biochemistry 199, article number: 110781. (10.1016/j.jinorgbio.2019.110781)
• Lorenzer, C. et al. 2019. Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing. European Journal of Pharmaceutics and Biopharmaceutics 141, pp. 37-50. (10.1016/j.ejpb.2019.05.015)
• Wahlich, J. et al. 2019. Nanomedicines for the delivery of biologics. Pharmaceutics 11(5), article number: 210. (10.3390/pharmaceutics11050210)
• Patel, S. G. et al. 2019. Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines. Scientific Reports 9(1), pp. -., article number: 6298. (10.1038/s41598-019-42456-8)
• Hamdy, R., Elseginy, S., Ziedan, N., Jones, A. and Westwell, A. 2019. New quinoline-based heterocycles as anticancer agents targeting Bcl-2. Molecules 24(7), pp. 1274. (10.3390/molecules24071274)

2018

• Gurney, L. R. I., Taggart, J., Tong, W., Jones, A. T., Robson, S. C. and Taggart, M. J. 2018. Inhibition of inflammatory changes in human myometrial cells by cell penetrating peptide and small molecule inhibitors of NFκB. Frontiers in Immunology 9, article number: 2966. (10.3389/fimmu.2018.02966)
• Sasso, L., Purdie, L., Grabowska, A., Jones, A. T. and Alexander, C. 2018. Time and cell-dependent effects of endocytosis inhibitors on the internalization of biomolecule markers and nanomaterials. Journal of Interdisciplinary Nanomedicine 3(2), pp. 67-81. (10.1002/jin2.39)
• He, L., Sayers, E. J., Watson, P. and Jones, A. T. 2018. Contrasting roles for actin in the cellular uptake of cell penetrating peptide conjugates. Scientific Reports 8(1), article number: 7318. (10.1038/s41598-018-25600-8)
• Sayers, E. J. et al. 2018. Switching of macromolecular ligand display by thermoresponsive polymers mediates endocytosis of multi-conjugate nanoparticles. Bioconjugate Chemistry 29(4), pp. 1030-1046. (10.1021/acs.bioconjchem.7b00704)

2017

• Kjos, I. et al. 2017. Rab7b modulates autophagic flux by interacting with Atg4B. EMBO reports 18(10), pp. 1727-1739. (10.15252/embr.201744069)
• Roberts-Dalton, H. D. et al. 2017. Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic. Nanoscale 9(36), pp. 13693-13706. (10.1039/C7NR04128D)
• Brazzale, C. et al. 2017. Control of targeting ligand display by pH-responsive polymers on gold nanoparticles mediates selective entry into cancer cells. Nanoscale 9(31), pp. 11137-11147. (10.1039/C7NR02595E)
• Hamdy, R. et al. 2017. Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2-amines as Bcl-2 inhibitory anticancer agents. Bioorganic & Medicinal Chemistry Letters 27(4), pp. 1037-1040. (10.1016/j.bmcl.2016.12.061)
• Ziedan, N. I. et al. 2017. Virtual screening, SAR and discovery of 5-(indole-3-yl)-2-[(2-nitrophenyl)amino] [1,3,4]-oxadiazole as a novel Bcl-2 inhibitor. Chemical Biology and Drug Design (10.1111/cbdd.12936)
• Wymant, J., Moody, P., Sayers, E. and Jones, A. T. 2017. Poster 433: Receptor-antibody clustering induced endocytosis of HER2 has therapeutic potential in breast cancer. Presented at: EACR-AACR-SIC Special Conference 2017: The Challenges of Optimising Immuno and Targeted Therapies From Cancer Biology to the Clinic, Florence, Italy, 24-27 June 2017.

2016

• Wymant, J., Hiscox, S., Westwell, A., Urbe, S., Clague, M. and Jones, A. T. 2016. The Role of BCA2 in the endocytic trafficking of EGFR and significance as a prognostic biomarker in cancer. Journal of Cancer 7(15), pp. 2388-2407. (10.7150/jca.15055)
• Kandil, S., Wymant, J., Kariuki, B., Jones, A. T., McGuigan, C. and Westwell, A. D. 2016. Novel cis-selective and non-epimerisable C3 hydroxy azapodophyllotoxins targeting microtubules in cancer cells. European Journal of Medicinal Chemistry 110, pp. 311-325. (10.1016/j.ejmech.2015.12.037)
• Gurney, L. R. I., Robson, S., Jones, A. T. and Taggart, M. 2016. Use of cell penetrating peptides to treat inflammatory responses in human uterine cells. Reproductive Sciences 23, pp. 292A-292A., article number: S-073. (10.1177/1933719116641257)

2015

• Moody, P. R., Sayers, E. J., Magnusson, J. P., Alexander, C., Borri, P., Watson, P. and Jones, A. T. 2015. Receptor crosslinking: a general method to trigger internalization and lysosomal targeting of therapeutic receptor: ligand complexes. Molecular Therapy 23(12), pp. 1888-1898. (10.1038/mt.2015.178)
• Lemmer, Y. et al. 2015. Mycolic acids, a promising mycobacterial ligand for targeting of nanoencapsulated drugs in tuberculosis. Journal of Controlled Release 211, pp. 94-104. (10.1016/j.jconrel.2015.06.005)
• Cilibrasi, V., Tsang, K. Y. I., Morelli, M., Solfa, F., Wiggins, H., Jones, A. T. and Westwell, A. D. 2015. Synthesis of substituted carbamo(dithioperoxo)thioates as potential BCA2-inhibitory anticancer agents. Tetrahedron Letters 56(20), pp. 2583-2585. (10.1016/j.tetlet.2015.03.132)
• Bahnsen, J. S., Franzyk, H., Sayers, E. J. and Jones, A. T. 2015. Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections. Pharmaceutical Research 32(5), pp. 1546-1556. (10.1007/s11095-014-1550-9)
• Pereira, P. et al. 2015. siRNA inhibition of endocytic pathways to characterize the cellular uptake mechanisms of folate functionalized glycol chitosan nanogels. Molecular Pharmaceutics 12(6), pp. 1970-1979., article number: 150416105321008. (10.1021/mp500785t)
• Wiggins, H. L., Wymant, J. M., Solfa, F., Hiscox, S. E., Taylor, K. M., Westwell, A. D. and Jones, A. T. 2015. Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells. Biochemical Pharmacology 93(3), pp. 332-342. (10.1016/j.bcp.2014.12.014)
• Webber, J. P. et al. 2015. Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes. Oncogene 34(3), pp. 290-302. (10.1038/onc.2013.560)
• He, L., Watson, P. D. and Jones, A. T. 2015. Visualizing actin architectures in cells incubated with cell-penetrating peptides. In: Langel, U. ed. Cell-Penetrating Peptides: Methods and Protocols., Vol. 1324. Methods in Molecular Biology Vol. 1324. Springer, pp. 247-259., (10.1007/978-1-4939-2806-4_16)

2014

• Sayers, E. J., Cleal, K., Eissa, N. G., Watson, P. D. and Jones, A. T. 2014. Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides. Journal of Controlled Release 195, pp. 55-62. (10.1016/j.jconrel.2014.07.055)

2013

• Kothayer, H. et al. 2013. Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides. Biorganic and Medicinal Chemistry Letters 23(24), pp. 6886-6889. (10.1016/j.bmcl.2013.09.087)
• Mart, R. J. et al. 2013. BH3 helix-derived biophotonic nanoswitches regulate cytochrome c release in permeabilised cells. Molecular BioSystems 9(11), pp. 2597-2603. (10.1039/c3mb70246d)
• Hamdy, R. et al. 2013. Synthesis and evaluation of 3-(benzylthio)-5-(1H-indol-3-yl)-1,2,4-triazol-4-amines as Bcl-2 inhibitory anticancer agents. Biorganic and Medicinal Chemistry Letters 23(8), pp. 2391-2394. (10.1016/j.bmcl.2013.02.029)
• Cleal, K., He, L., Watson, P. D. and Jones, A. T. 2013. Endocytosis, intracellular traffic and fate of cell penetrating peptide based conjugates and nanoparticles. Current Pharmaceutical Design 19(16), pp. 2878-2894. (10.2174/13816128113199990297)

2012

• Jones, A. T. and Sayers, E. J. 2012. Cell entry of cell penetrating peptides and tales of tails wagging dogs. Journal of Controlled Release 161(2), pp. 582-591. (10.1016/j.jconrel.2012.04.003)
• Al Soraj, M. et al. 2012. siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat. Journal of Controlled Release 161(1), pp. 132-141. (10.1016/j.jconrel.2012.03.015)
• Bailey, D. et al. 2012. An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases. Acta Crystallographica Section D: Biological Crystallography 68(5), pp. 541-552. (10.1107/S0907444912004817)

2011

• Watkins, C. L., Sayers, E. J., Allender, C. J., Barrow, D. A., Fegan, C. D., Brennan, P. and Jones, A. T. 2011. Co-operative membrane disruption between cell-penetrating peptide and cargo: implications for the therapeutic use of the Bcl-2 converter peptide D-NuBCP-9-r8. Molecular Therapy 19(12), pp. 2124-2132. (10.1038/mt.2011.175)
• Vercauteren, D. et al. 2011. Dynamic colocalization microscopy to characterize intracellular trafficking of nanomedicines. ACS Nano 5(10), pp. 7874-7884. (10.1021/nn2020858)
• Vercauteren, D. et al. 2011. Flotillin-dependent endocytosis and a phagocytosis-like mechanism for cellular internalization of disulfide-based poly(amido amine)/DNA polyplexes. Biomaterials 32(11), pp. 3072-3084. (10.1016/j.biomaterials.2010.12.045)
• Fricke, T. et al. 2011. Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins. Bioconjugate Chemistry 22(9), pp. 1763-1767. (10.1021/bc200338u)

2010

• Fricke, T., Mart, R. J., Watkins, C. L., Jones, A. T. and Allemann, R. K. 2010. Click chemistry for the generation of cell permeable apoptotic peptides. Drug Discovery Today 15(23-24), pp. 1088-1088. (10.1016/j.drudis.2010.09.375)
• Sweeney, M., Watkins, C. L., Jones, A. T. and Taggart, M. J. 2010. Octaarginine mediated delivery of fluorescent cargo to human smooth muscle cells. Drug Discovery Today 15(23-24), pp. 1085-1085. (10.1016/j.drudis.2010.09.367)
• Gumbleton, M. and Jones, A. T. 2010. Cellular delivery of therapeutic macromolecules (CDTM) international Symposium 2010: lessons and progress from inter-disciplinary science. Drug Discovery Today 15(23-24), pp. 1079-180. (10.1016/j.drudis.2010.10.010)
• Al-Soraj, M. H., Watkins, C. L., Vercauteren, D., De Smedt, S., Braeckmans, K. and Jones, A. T. 2010. siRNA versus pharmacological inhibition of endocytic pathways for studying cellular uptake of cell penetrating peptides and other drug delivery vectors. Drug Discovery Today 15(23-24), pp. 1103-1103. (10.1016/j.drudis.2010.09.411)
• Vercauteren, D. et al. 2010. The use of inhibitors to study endocytic pathways of gene carriers: Optimization and pitfalls. Molecular Therapy 18(3), pp. 561-569. (10.1038/mt.2009.281)
• Bruyere, H., Westwell, A. and Jones, A. T. 2010. Tuning the pH sensitivities of orthoester based compounds for drug delivery applications by simple chemical modification. Bioorganic & Medicinal Chemistry Letters 20(7), pp. 2200-2203. (10.1016/j.bmcl.2010.02.035)
• Jones, A. T. 2010. Uptake and intracellular dynamics of proteins internalized by cell-penetrating peptides. In: Weissig, V. and D'Souza, G. G. M. eds. Organelle-Specific Pharmaceutical Nanotechnology. Hoboken, NJ.: John Wiley & Sons, pp. 263-288., (10.1002/9780470875780.ch15)

2009

• Watkins, C. L., Brennan, P., Fegan, C. D., Takayama, K., Nakase, I., Futaki, S. and Jones, A. T. 2009. Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD. Journal of Controlled Release 140(3), pp. 237-244. (10.1016/j.jconrel.2009.04.028)
• Hughes, M. L., John, D. N. and Jones, A. T. 2009. Information provided with dispensed medicines: What role does language choice play? A perspective from Wales [Abstract]. International Journal of Pharmacy Practice 17(S2), pp. B44-B45. (10.1211/096176709789037128)
• Hughes, M. L., John, D. N., Jones, A. T., Jones, E. and Wilkins, M. L. 2009. Language issues in the community pharmacy: a perspective from Wales. International Journal of Pharmacy Practice 17(3), pp. 157-163. (10.1211/ijpp.17.03.0006)
• Hughes, M. L., John, D. N. and Jones, A. T. 2009. Medicines use reviews and language choice. International Journal of Pharmacy Practice 17(s1), pp. A41. (10.1211/096176709787640689)
• Watkins, C. L., Schmaljohann, D., Futaki, S. and Jones, A. T. 2009. Low concentration thresholds of plasma membranes for rapid energy-independent translocation of a cell-penetrating peptide. Biochemical Journal 420(2), pp. 179-189. (10.1042/BJ20090042)
• Jin, J. and Jones, A. T. 2009. The pH sensitive probe 5-(and-6)-carboxyl seminaphthorhodafluor is a substrate for the multidrug resistance-related protein MRP1. International Journal of Cancer 124(1), pp. 233-238. (10.1002/ijc.23892)

2008

• Kosuge, M., Takeuchi, T., Nakase, I., Jones, A. and Futaki, S. 2008. Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans. Bioconjugate Chemistry 19(3), pp. 656-664. (10.1021/bc700289w)
• Jin, J., Pastrello, D., Penning, N. A. and Jones, A. T. 2008. Clustering of endocytic organelles in parental and drug-resistant myeloid leukaemia cell lines lacking centrosomally organised microtubule arrays. The International Journal of Biochemistry & Cell Biology 40(10), pp. 2240-2252. (10.1016/j.bioce1.2008.03.004)
• Jones, A. T. 2008. Gateways and tools for drug delivery: Endocytic pathways and the cellular dynamics of cell penetrating peptides. International Journal of Pharmaceutics 354(1-2), pp. 34-38. (10.1016/j.ijpharm.2007.10.046)
• Hughes, M. L., John, D. N. and Jones, A. T. 2008. The role of the Welsh language in community pharmacy service provision in Wales. London: Pharmacy Practice Research Trust.

2007

• McGuigan, C. et al. 2007. Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus. Journal of Antimicrobial Chemotherapy 60(6), pp. 1316-1330. (10.1093/jac/dkm376)
• Jones, A. T. 2007. Enclocytic pathways: gateways for intracellular drug delivery [Abstract]. Journal of Pharmacy and Pharmacology 59(S1), pp. A72., article number: 195. (10.1211/002235707781850023)
• Fretz, M. M. et al. 2007. Temperature-, concentration- and cholesterol-dependent translocation of L- and D-octa-arginine across the plasma and nuclear membrane of CD34+ leukaemia cells. Biochemical Journal 403(2), pp. 335-342. (10.1042/BJ20061808)
• Futaki, S., Nakase, I., Taclokoro, A., Takeuchi, T. and Jones, A. T. 2007. Arginine-rich peptides and their internalization mechanisms. Biochemical Society Transactions 35(4), pp. 784-787.
• Greco, F., Vicent, M. J., Gee, S., Jones, A. T., Gee, J. M. W., Nicholson, R. I. and Duncan, R. 2007. Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells. Journal of Controlled Release 117(1), pp. 28-39. (10.1016/j.jconrel.2006.10.012)
• Jones, A. T. 2007. Macropinocytosis: searching for an endocytic identity and role in the uptake of cell penetrating peptides. Journal of Cellular and Molecular Medicine 11(4), pp. 670-684. (10.1111/j.1582-4934.2007.00062.x)
• Maiti, K. K. et al. 2007. Guanidine-containing molecular transporters: Sorbitol-based transporters show high intracellular selectivity toward mitochondria. Angewandte Chemie International Edition 46(31), pp. 5880-5884. (10.1002/anie.200701346)
• Manunta, M., Izzo, L., Duncan, R. and Jones, A. T. 2007. Establishment of subcellular fractionation techniques to monitor the intracellular fate of polymer therapeutics II. Identification of endosomal and lysosomal compartments in HepG2 cells combining single-step subcellular fractionation with fluorescent imaging. Journal of Drug Targeting 15(1), pp. 37-50. (10.1080/10611860601010330)
• Peeters, L., Jones, A. T., Demeester, J., De Smedt, S. and Sanders, N. 2007. Post-PEGylated lipoplexes are promising vehicles for gene delivery in RPE cells. Human Gene Therapy 18(10), pp. 1046-1047.
• Peeters, L., Sanders, N. N., Jones, A. T., Demeester, J. and De Smedt, S. C. 2007. Post-pegylated lipoplexes are promising vehicles for gene delivery in RPE cells. Journal of Controlled Release 121(3), pp. 208-217. (10.1016/j.jconrel.2007.05.033)
• Seib, F. P., Jones, A. T. and Duncan, R. 2007. Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells. Journal of Controlled Release 117(3), pp. 291-300. (10.1016/j.jconrel.2006.10.020)

2006

• Berna, M. et al. 2006. Novel monodisperse PEG-dendrons as new tools for targeted drug delivery: Synthesis, characterisation and cellular uptake. Biomacromolecules 7(1), pp. 146-153. (10.1021/bm050480s)
• Fretz, M. M. et al. 2006. Effects of Na+/H+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine. Journal of Controlled Release 116(2), pp. 247-254. (10.1016/j.jconrel.2006.07.009)
• Al-Taei, S., Penning, N. A., Simpson, J. C., Futaki, S., Takeuchi, T., Nakase, I. and Jones, A. T. 2006. Intracellular traffic and fate of protein transduction domains HIV-1 TAT peptide and octaarginine. Implications for their utilization as drug delivery vectors. Bioconjugate Chemistry 17(1), pp. 90-100. (10.1021/bc050274h)
• Seib, F. P., Jones, A. T. and Duncan, R. 2006. Establishment of subcellular fractionation techniques to monitor the intracellular fate of polymer therapeutics I. Differential centrifugation fractionation B16F10 cells and use to study the intracellular fate of HPMA copolymer-doxorubicin. Journal of drug targeting 14(6), pp. 375-390. (10.1080/10611860600833955)

2005

• Hughes, M. L., John, D. N., Jones, A. T., Wilkins, M. L. and Jones, E. H. 2005. Patients' views on use of the Welsh language in community pharmacy: an exploratory study. International Journal of Pharmacy Practice 13(s1), pp. R93. (10.1211/096176705777341217/pdf)
• Hughes, M. L., John, D. N. and Jones, A. T. 2005. Exploring the role of the Welsh language in community pharmacy: the professionals' views. International Journal of Pharmacy Practice 13(s1), pp. R94. (10.1211/096176705777341217/pdf)
• Watson, P. D., Jones, A. T. and Stephens, D. J. 2005. Intracellular trafficking pathways and drug delivery: fluorescence imaging of living and fixed cells. Advanced Drug Delivery Reviews 57(1), pp. 43-61. (10.1016/j.addr.2004.05.003)
• Simpson, J. C. and Jones, A. T. 2005. Early endocytic Rabs: functional prediction to functional characterization. In: McIlhinney, J. and Hooper, N. eds. Biochemical Society Symposia Volume 72: Lipids, Rafts and Traffic. Portland Press, pp. 99-108.

2004

• Nakase, I. et al. 2004. Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement. Molecular Therapy 10(6), pp. 1011-22. (10.1016/j.ymthe.2004.08.010)
• Simpson, J. C., Griffiths, G., Wessling-Resnick, M., Fransen, J. A. M., Bennett, H. and Jones, A. T. 2004. A role for the small GTPase Rab21 in the early endocytic pathway. Journal of cell science 117(26), pp. 6297-6311. (10.1242/jcs.01560)

2003

• Jones, A. T., Gumbleton, M. and Duncan, R. 2003. Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems. Advanced Drug Delivery Reviews 55(11), pp. 1353-1367. (10.1016/j.addr.2003.07.002)

2001

• Jones, A. T. 2001. Intracellular drug delivery. Workshop teport from the 28th International Symposium on Controlled Release of Bioactive Materials, San Diego, 23-24 June 2001. Traffic 2(12), pp. 917-920. (10.1034/j.1600-0854.2001.21207.x)

1998

• Jones, A. T., Mills, I. G., Scheidig, A. J., Alexandrov, K. and Clague, M. J. 1998. Inhibition of endosome fusion by wortmannin persists in the presence of activated rab5. Molecular Biology of the Cell 9(2), pp. 323-332. (10.1091/mbc.9.2.323)
• Jones, A. T. and Wessling-Resnick, M. 1998. Inhibition of in vitro endosomal vesicle fusion activity by aminoglycoside antibiotics. Journal of Biological Chemistry 273(39), pp. 25301-25309. (10.1074/jbc.273.39.25301)

1997

• Jones, A. T. and Clague, M. J. 1997. Regulation of early endosome fusion by phospholipase D activity. Biochemical and Biophysical Research Communications 236(2), pp. 285-288. (10.1006/bbrc.1997.6962)
• Gaffet, P., Jones, A. T. and Clague, M. J. 1997. Inhibition of calcium-independent mannose 6-phosphate receptor incorporation into trans-Golgi network-derived clathrin-coated vesicles by wortmannin. Journal of Biological Chemistry 272(39), pp. 24170-24175. (10.1074/jbc.272.39.24170)