![Emre Kopanoglu](https://profiles-cardiff.imgix.net/attachments/3018?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Trosolwyg
Crynodeb ymchwil
Mae Delweddu Cyseiniant Magnetig yn ddull delweddu pwerus gyda gwrthgyferbyniad meinwe meddal uchel, diogelwch cynhenid oherwydd diffyg ymbelydredd ïoneiddio, a chymhareb signal-i-sŵn sy'n ddigonol yn ddiagnostig. Nod fy ymchwil yw gwella ansawdd delweddau diagnostig yn ogystal â chysur a diogelwch cleifion mewn MRI, ac mae'n cynnwys prosesu signalau / delwedd, modelu cyfrifiadurol, a chaledwedd delweddu newydd.
Gyda llawer o sganiau MRI yn para sawl munud, mae symudiad cleifion yn broblem ddifrifol. Os nad yw'n cael ei gywiro mewn amser real, mae llawer o batrymau cynnig yn newid y gyfrol ddelwedd, ac felly yn gwneud data delweddu anghyson ac yn golygu bod angen ail-sganio'r claf. Ar y naill law, ar gryfderau maes isaf, gall technegau cywiro cynnig amser real (rhagolygol) addasu'r cyfaint delweddu mewn amser real. Fodd bynnag, mae cryfderau maes is yn golygu cymhareb signal-i-sŵn is a chymhareb cyferbyniad-i-sŵn, hy ansawdd delwedd is. Ar y llaw arall, mae MRI maes ultra-uchel (UHF, >3T) yn cynnig llawer o fanteision o ran ansawdd a chyferbyniad delwedd. Yn anffodus, mae MRI UHF yn dioddef o amrywiadau cyferbyniad annymunol ar draws y ddelwedd. Er y gellir digolledu amrywiadau o'r fath am ddefnyddio curiadau amledd radio wedi'u teilwra a systemau trosglwyddo aml-sianel (trosglwyddo cyfochrog), mae dylunio corbys o'r fath yn cymryd o fwy na sawl eiliad i ychydig funudau gyda llawer o algorithmau. Felly, nid yw cywiro cynnig amser real wedi bod yn bosibl eto gyda chorbys o'r fath. Mae fy ymchwil cyfredol yn canolbwyntio ar ddylunio curiadau trosglwyddo cyfochrog mewn amser real.
Cyhoeddiad
2024
- Blanter, K., Plumley, A. and Kopanoglu, E. 2024. The effects of simulated SAR data processing methods and network parameter tuning on gridding artifacts and network estimation accuracy. Presented at: 2024 ISMRM & ISMRT Annual Meeting & Exhibition, Singapore, 4-9 May 2024.
- Blanter, K., Plumley, A., Malik, S. and Kopanoglu, E. 2024. Estimating variations in SAR calculations due to within-scan patient motion using cGANs for parallel RF transmission at ultrahigh field MRI. Presented at: 2024 ISMRM & ISMRT Annual Meeting & Exhibition, Singapore, 4-9 May, 2024.
2023
- Blanter, K., Plumley, A., Malik, S. and Kopanoglu, E. 2023. Towards applying deep learning to predict rigid motion-induced changes in Q-matrices from UHF-MRI pTx simulations. Presented at: 2023 ISMRM & ISMRT Annual Meeting & Exhibition, 03 - 08 June, 2023.
- Kopanoglu, E. 2023. Actual patient position versus safety models: specific absorption rate implications of initial head position at ultrahigh field MRI. NMR in Biomedicine 36(5), article number: e4876. (10.1002/nbm.4876)
2022
- Collins, J. D. et al. 2022. Magnetic resonance imaging during a pandemic: recommendations by the ISMRM safety committee. Journal of Magnetic Resonance Imaging 55(5), pp. 1322-1339. (10.1002/jmri.28006)
- Plumley, A., Watkins, L., Treder, M., Liebig, P., Murphy, K. and Kopanoglu, E. 2022. Rigid motion-resolved B1+ prediction using deep learning for real-time parallel-transmission pulse design. Magnetic Resonance in Medicine 87(5), pp. 2254-2270. (10.1002/mrm.29132)
- Kopanoglu, E. 2022. Head position related SAR uncertainty depends on slice orientation and pulse complexity. Presented at: Joint Annual Meeting ISMRM-ESMRMB, London, UK, 07-12 May 2022Proceedings of the Joint Annual Meeting ISMRM-ESMRMB. Vol. 2870.
2021
- Watkins, L., Plumley, A., Murphy, K. and Kopanoglu, E. 2021. Motion robust parallel transmission excitation pulse design for ultra-high field MRI. Presented at: 2021 ISMRM & SMRT Annual Meeting & Exhibition, Virtual, 15-20 May 2021.
- Gholam, J. A. et al. 2021. aDWI-BIDS: advanced diffusion weighted imaging metadata for the brain imaging data structure. Presented at: ISMRM & SMRT Annual Meeting & Exhibition, Virtual, 15-20 May 2021.
- Plumley, A., Schmid, P. and Kopanoglu, E. 2021. Parallel transmit coil dimensions affect SAR sensitivity to motion at 7T. Presented at: ISMRM & SMRT Annual Meeting & Exhibition, Virtual, 15-20 May 2021.
- Kopanoglu, E. 2021. Patient specific parallel transmit pulses are patient position dependent while safety models are fixed: safety implications. Presented at: 2021 ISMRM & SMRT Annual Meeting & Exhibition, Virtual, 15-20 May 2021.
- Plumley, A., Watkins, L., Murphy, K. and Kopanoglu, E. 2021. Motion-resolved B1+ prediction using deep learning for real-time pTx pulse-design. Presented at: ISMRM & SMRT Annual Meeting & Exhibition, Virtual, 15-20 May 2021.
2020
- Kopanoglu, E., Deniz, C. M., Erturk, M. A. and Wise, R. G. 2020. Specific absorption rate implications of within-scan patient head motion for ultra-high field MRI. Magnetic Resonance in Medicine 84(5), pp. 2724-2738. (10.1002/mrm.28276)
- Kopanoglu, E., Deniz, C. M. and Wise, R. G. 2020. Simultaneous multi-slice imaging reduces sensitivity of local-SAR to patient motion at 7T. Presented at: ISMRM 28th Annual Meeting & Exhibition, Sydney Australia, 08-14 August 2020Proceedings of the ISMRM 28th annual meeting and exhibition. Vol. 3691.
- Kopanoglu, E., Gungor, A., Kilic, T., Ulku Saritas, E., Oguz, K. K., Culcur, T. and Guven, H. E. 2020. Simultaneous use of individual and joint regularization terms in compressive sensing: Joint reconstruction of multi-channel multi-contrast MRI acquisitions. NMR in Biomedicine 33(4), article number: e4247. (10.1002/nbm.4247)
- Watkins, L., Plumley, A., Murphy, K. and Kopanoglu, E. 2020. Motion robust parallel transmission excitation pulse design for ultra-high field MRI. Presented at: ISMRM & SMRT Virtual Conference & Exhibition 2020, Online, 8-14 August 2020.
- Plumley, A., Watkins, L. and Kopanoglu, E. 2020. Large tip-angle, motion robust pulse design for parallel transmission at 7T using composite B1 distributions. Presented at: ISMRM & SMRT Virtual Conference & Exhibition 2020, Online, 8-14 August 2020.
2019
- Senel, L. K. et al. 2019. Statistically segregated k-space sampling for accelerating multiple-acquisition MRI. IEEE Transactions on Medical Imaging 38(7), pp. 1701-1714. (10.1109/TMI.2019.2892378)
- Kopanoglu, E., Plumley, A., Deniz, C. M., Erturk, A. M. and Wise, R. G. 2019. Implications of within-scan patient head motion on B1+ homogeneity and specific absorption rate at 7T. Presented at: ISMRM 27th Annual Meeting & Exhibition, Montréal, QC, Canada, 11-16 May 2019Proceedings of the ISMRM 27th annual meeting and exhibition. Vol. 4686.
- Kopanoglu, E., Güngör, A., Kilic, T., Saritas, E. U., Oguz, K. K., Çukur, T. and Guven, H. E. 2019. Multi-channel multi-contrast reconstructions via simultaneous use of individual and joint regularization terms. Presented at: ISMRM 27th Annual Meeting & Exhibition, Montréal, QC, Canada, 11-16 May 2019Proceedings of the ISMRM 27th Annual Meeting and Exhibition. pp. 4748.
- Kopanoglu, E., Tachrount, M., Meliado, E. F., Klomp, D., Evans, J. and Wise, R. G. 2019. Random RF shimming may conceal possible local SAR hotspots for asymmetric parallel transmit coils. Presented at: ISMRM 27th Annual Meeting & Exhibition, Montréal, QC, Canada, 11-16 May 2019Proceedings of the ISMRM 27th Annual Meeting and Exhibition. pp. 4158.
2018
- Kopanoglu, E. 2018. Near real-time parallel-transmit pulse design. Presented at: Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France, 16-21 June 2018Proceedings of the Joint ISMRM - ESMRMB Meeting. pp. 3392.
- Kopanoglu, E., Güngör, A., Kilic, T., Saritas, E. U., Çukur, T. and Guven, H. E. 2018. Compressive sensing reconstruction for multi-contrast data with unequal acceleration rates. Presented at: Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France, 16-21 June 2018Proceedings of the Joint Annual Meeting ISMRM-ESMRMB 2018. pp. 3534.
2017
- Gungor, A., Kopanoglu, E., Cukur, T. and Guven, H. 2017. A synthesis-based approach to compressive multi-contrast magnetic resonance imaging. Presented at: IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017), Melbourne, Australia, 18-21 Apr 2017IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017). IEEE, (10.1109/ISBI.2017.7950615)
- Wang, H., Tam, L., Kopanoglu, E., Peters, D. C., Constable, R. T. and Galiana, G. 2017. O-space with high resolution readouts outperforms radial imaging. Magnetic Resonance Imaging 37, pp. 107-115. (10.1016/j.mri.2016.11.012)
- Styner, M. A., Angelini, E. D., Güngör, A., Kopanoglu, E., Çukur, T. and Güven, H. E. 2017. Fast recovery of compressed multi-contrast magnetic resonance images. Presented at: Medical Imaging 2017: Image Processing, Orlando, FL, USA, 11 February 2017Proc. SPIE 10133, Medical Imaging 2017: Image Processing, Vol. 10133. Society of Photo-optical Instrumentation Engineers pp. 101331R., (10.1117/12.2252101)
- Kopanoglu, E., Güngör, A., Kilic, T., Saritas, E. U., Çukur, T. and Guven, H. E. 2017. Joint reconstruction of multi-contrast images: compressive sensing reconstruction using both joint and individual regularization functions. Presented at: ISMRM 25th Annual Meeting & Exhibition SMRT 26th Annual Meeting, Honolulu, HI, USA, 22-27 April 2017Proceedings of the 25th ISMRM 25th Annual Meeting & Exhibition. pp. 3875.
2016
- Gungor, A., Kopanoglu, E., Cukur, T. and Guven, H. E. 2016. Compressed multi-contrast magnetic resonance image reconstruction using augmented lagrangian method. Presented at: 2016 24th Signal Processing and Communication Application Conference (SIU), Zonguldak, Turkey, 16-19 May 20162016 24th Signal Processing and Communication Application Conference (SIU). IEEE, (10.1109/SIU.2016.7496157)
- Kopanoglu, E., Wang, H., Peters, D. C., Galiana, G. and Constable, R. T. 2016. Accelerated imaging of sub-volumes using region-of-interest focused O-Space: experimental verification of rOi-Space. Presented at: ISMRM 24th Annual Meeting & Exhibition, Singapore, 07-13 May 2016Proceedings of the ISMRM 24th annual meeting and exhibition.
- Kopanoglu, E., Wang, H., Galiana, G. and Constable, R. T. 2016. Motion tracking using nonlinear gradient fields: experimental verification and oblique slices. Presented at: ISMRM 24th Annual Meeting & Exhibition, Singapore, 07-13 May 2016Proceedings of the ISMRM 24th annual meeting and exhibition.
- Wang, H., Kopanoglu, E., Constable, R. T. and Galiana, G. 2016. Low-Rank O-Space Reconstruction. Presented at: ISMRM 24th Annual Meeting & Exhibition, Singapore, 07-13 May 2016.
- Wang, H., Tam, L., Kopanoglu, E., Peters, D. C., Constable, R. T. and Galiana, G. 2016. Experimental O-space turbo spin echo imaging. Magnetic Resonance in Medicine 75(4), pp. 1654-1661. (10.1002/mrm.25741)
2015
- Kopanoglu, E. and Constable, R. T. 2015. Radiofrequency pulse design using nonlinear gradient magnetic fields. Magnetic Resonance in Medicine 74(3), pp. 826-839. (10.1002/mrm.25423)
- Kopanoglu, E., Galiana, G. and Constable, R. T. 2015. Motion navigation using non-linear gradient fields. Presented at: ISMRM 23rd Annual Meeting & Exhibition, Toronto, Ontario, Canada, 30 May-5 June 2015Proceedings of the ISMRM 23rd annual meeting and exhibition.
- Kopanoglu, E., Wang, H., Wan, Y., Peters, D. C., Galiana, G. and Constable, R. T. 2015. rOi-Space: accelerated imaging of sub-volumes using ROI focused O-Space. Presented at: ISMRM 23rd Annual Meeting & Exhibition, Toronto, Ontario, Canada, 30 May-5 June 2015Proceedings of the ISMRM 23rd annual meeting and exhibition.
2014
- Wang, H., Tam, L., Kopanoglu, E., Peters, D., Constable, R. T. and Galiana, G. 2014. Accelerate data acquisition using Turbo Spin Echo and O-Space. Presented at: 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI), 29 April - 2 May 2014Biomedical Imaging (ISBI), 2014 IEEE 11th International Symposium on. IEEE pp. 874-877., (10.1109/ISBI.2014.6868010)
2013
- Kopanoglu, E., Yilmaz, U., Gokhalk, Y. and Atalar, E. 2013. Specific absorption rate reduction using nonlinear gradient fields. Magnetic Resonance in Medicine 70(2), pp. 537-546. (10.1002/mrm.24478)
2012
- Turk, E. A., Kopanoglu, E., Guney, S., Bugdayci, K. E., Ider, Y. Z., Erturk, V. B. and Atalar, E. 2012. A simple analytical expression for the gradient induced potential on active implants during MRI. IEEE Transactions on Biomedical Engineering 59(10), pp. 2845-2851. (10.1109/TBME.2012.2212190)
2011
- Kopanoglu, E., Erturk, V. B. and Atalar, E. 2011. Analytic expressions for the ultimate intrinsic signal-to-noise ratio and ultimate intrinsic specific absorption rate in MRI. Magnetic Resonance in Medicine 66(3), pp. 846-858. (10.1002/mrm.22830)
Cynadleddau
- Blanter, K., Plumley, A. and Kopanoglu, E. 2024. The effects of simulated SAR data processing methods and network parameter tuning on gridding artifacts and network estimation accuracy. Presented at: 2024 ISMRM & ISMRT Annual Meeting & Exhibition, Singapore, 4-9 May 2024.
- Blanter, K., Plumley, A., Malik, S. and Kopanoglu, E. 2024. Estimating variations in SAR calculations due to within-scan patient motion using cGANs for parallel RF transmission at ultrahigh field MRI. Presented at: 2024 ISMRM & ISMRT Annual Meeting & Exhibition, Singapore, 4-9 May, 2024.
- Blanter, K., Plumley, A., Malik, S. and Kopanoglu, E. 2023. Towards applying deep learning to predict rigid motion-induced changes in Q-matrices from UHF-MRI pTx simulations. Presented at: 2023 ISMRM & ISMRT Annual Meeting & Exhibition, 03 - 08 June, 2023.
- Kopanoglu, E. 2022. Head position related SAR uncertainty depends on slice orientation and pulse complexity. Presented at: Joint Annual Meeting ISMRM-ESMRMB, London, UK, 07-12 May 2022Proceedings of the Joint Annual Meeting ISMRM-ESMRMB. Vol. 2870.
- Watkins, L., Plumley, A., Murphy, K. and Kopanoglu, E. 2021. Motion robust parallel transmission excitation pulse design for ultra-high field MRI. Presented at: 2021 ISMRM & SMRT Annual Meeting & Exhibition, Virtual, 15-20 May 2021.
- Gholam, J. A. et al. 2021. aDWI-BIDS: advanced diffusion weighted imaging metadata for the brain imaging data structure. Presented at: ISMRM & SMRT Annual Meeting & Exhibition, Virtual, 15-20 May 2021.
- Plumley, A., Schmid, P. and Kopanoglu, E. 2021. Parallel transmit coil dimensions affect SAR sensitivity to motion at 7T. Presented at: ISMRM & SMRT Annual Meeting & Exhibition, Virtual, 15-20 May 2021.
- Kopanoglu, E. 2021. Patient specific parallel transmit pulses are patient position dependent while safety models are fixed: safety implications. Presented at: 2021 ISMRM & SMRT Annual Meeting & Exhibition, Virtual, 15-20 May 2021.
- Plumley, A., Watkins, L., Murphy, K. and Kopanoglu, E. 2021. Motion-resolved B1+ prediction using deep learning for real-time pTx pulse-design. Presented at: ISMRM & SMRT Annual Meeting & Exhibition, Virtual, 15-20 May 2021.
- Kopanoglu, E., Deniz, C. M. and Wise, R. G. 2020. Simultaneous multi-slice imaging reduces sensitivity of local-SAR to patient motion at 7T. Presented at: ISMRM 28th Annual Meeting & Exhibition, Sydney Australia, 08-14 August 2020Proceedings of the ISMRM 28th annual meeting and exhibition. Vol. 3691.
- Watkins, L., Plumley, A., Murphy, K. and Kopanoglu, E. 2020. Motion robust parallel transmission excitation pulse design for ultra-high field MRI. Presented at: ISMRM & SMRT Virtual Conference & Exhibition 2020, Online, 8-14 August 2020.
- Plumley, A., Watkins, L. and Kopanoglu, E. 2020. Large tip-angle, motion robust pulse design for parallel transmission at 7T using composite B1 distributions. Presented at: ISMRM & SMRT Virtual Conference & Exhibition 2020, Online, 8-14 August 2020.
- Kopanoglu, E., Plumley, A., Deniz, C. M., Erturk, A. M. and Wise, R. G. 2019. Implications of within-scan patient head motion on B1+ homogeneity and specific absorption rate at 7T. Presented at: ISMRM 27th Annual Meeting & Exhibition, Montréal, QC, Canada, 11-16 May 2019Proceedings of the ISMRM 27th annual meeting and exhibition. Vol. 4686.
- Kopanoglu, E., Güngör, A., Kilic, T., Saritas, E. U., Oguz, K. K., Çukur, T. and Guven, H. E. 2019. Multi-channel multi-contrast reconstructions via simultaneous use of individual and joint regularization terms. Presented at: ISMRM 27th Annual Meeting & Exhibition, Montréal, QC, Canada, 11-16 May 2019Proceedings of the ISMRM 27th Annual Meeting and Exhibition. pp. 4748.
- Kopanoglu, E., Tachrount, M., Meliado, E. F., Klomp, D., Evans, J. and Wise, R. G. 2019. Random RF shimming may conceal possible local SAR hotspots for asymmetric parallel transmit coils. Presented at: ISMRM 27th Annual Meeting & Exhibition, Montréal, QC, Canada, 11-16 May 2019Proceedings of the ISMRM 27th Annual Meeting and Exhibition. pp. 4158.
- Kopanoglu, E. 2018. Near real-time parallel-transmit pulse design. Presented at: Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France, 16-21 June 2018Proceedings of the Joint ISMRM - ESMRMB Meeting. pp. 3392.
- Kopanoglu, E., Güngör, A., Kilic, T., Saritas, E. U., Çukur, T. and Guven, H. E. 2018. Compressive sensing reconstruction for multi-contrast data with unequal acceleration rates. Presented at: Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France, 16-21 June 2018Proceedings of the Joint Annual Meeting ISMRM-ESMRMB 2018. pp. 3534.
- Gungor, A., Kopanoglu, E., Cukur, T. and Guven, H. 2017. A synthesis-based approach to compressive multi-contrast magnetic resonance imaging. Presented at: IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017), Melbourne, Australia, 18-21 Apr 2017IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017). IEEE, (10.1109/ISBI.2017.7950615)
- Styner, M. A., Angelini, E. D., Güngör, A., Kopanoglu, E., Çukur, T. and Güven, H. E. 2017. Fast recovery of compressed multi-contrast magnetic resonance images. Presented at: Medical Imaging 2017: Image Processing, Orlando, FL, USA, 11 February 2017Proc. SPIE 10133, Medical Imaging 2017: Image Processing, Vol. 10133. Society of Photo-optical Instrumentation Engineers pp. 101331R., (10.1117/12.2252101)
- Kopanoglu, E., Güngör, A., Kilic, T., Saritas, E. U., Çukur, T. and Guven, H. E. 2017. Joint reconstruction of multi-contrast images: compressive sensing reconstruction using both joint and individual regularization functions. Presented at: ISMRM 25th Annual Meeting & Exhibition SMRT 26th Annual Meeting, Honolulu, HI, USA, 22-27 April 2017Proceedings of the 25th ISMRM 25th Annual Meeting & Exhibition. pp. 3875.
- Gungor, A., Kopanoglu, E., Cukur, T. and Guven, H. E. 2016. Compressed multi-contrast magnetic resonance image reconstruction using augmented lagrangian method. Presented at: 2016 24th Signal Processing and Communication Application Conference (SIU), Zonguldak, Turkey, 16-19 May 20162016 24th Signal Processing and Communication Application Conference (SIU). IEEE, (10.1109/SIU.2016.7496157)
- Kopanoglu, E., Wang, H., Peters, D. C., Galiana, G. and Constable, R. T. 2016. Accelerated imaging of sub-volumes using region-of-interest focused O-Space: experimental verification of rOi-Space. Presented at: ISMRM 24th Annual Meeting & Exhibition, Singapore, 07-13 May 2016Proceedings of the ISMRM 24th annual meeting and exhibition.
- Kopanoglu, E., Wang, H., Galiana, G. and Constable, R. T. 2016. Motion tracking using nonlinear gradient fields: experimental verification and oblique slices. Presented at: ISMRM 24th Annual Meeting & Exhibition, Singapore, 07-13 May 2016Proceedings of the ISMRM 24th annual meeting and exhibition.
- Wang, H., Kopanoglu, E., Constable, R. T. and Galiana, G. 2016. Low-Rank O-Space Reconstruction. Presented at: ISMRM 24th Annual Meeting & Exhibition, Singapore, 07-13 May 2016.
- Kopanoglu, E., Galiana, G. and Constable, R. T. 2015. Motion navigation using non-linear gradient fields. Presented at: ISMRM 23rd Annual Meeting & Exhibition, Toronto, Ontario, Canada, 30 May-5 June 2015Proceedings of the ISMRM 23rd annual meeting and exhibition.
- Kopanoglu, E., Wang, H., Wan, Y., Peters, D. C., Galiana, G. and Constable, R. T. 2015. rOi-Space: accelerated imaging of sub-volumes using ROI focused O-Space. Presented at: ISMRM 23rd Annual Meeting & Exhibition, Toronto, Ontario, Canada, 30 May-5 June 2015Proceedings of the ISMRM 23rd annual meeting and exhibition.
- Wang, H., Tam, L., Kopanoglu, E., Peters, D., Constable, R. T. and Galiana, G. 2014. Accelerate data acquisition using Turbo Spin Echo and O-Space. Presented at: 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI), 29 April - 2 May 2014Biomedical Imaging (ISBI), 2014 IEEE 11th International Symposium on. IEEE pp. 874-877., (10.1109/ISBI.2014.6868010)
Erthyglau
- Kopanoglu, E. 2023. Actual patient position versus safety models: specific absorption rate implications of initial head position at ultrahigh field MRI. NMR in Biomedicine 36(5), article number: e4876. (10.1002/nbm.4876)
- Collins, J. D. et al. 2022. Magnetic resonance imaging during a pandemic: recommendations by the ISMRM safety committee. Journal of Magnetic Resonance Imaging 55(5), pp. 1322-1339. (10.1002/jmri.28006)
- Plumley, A., Watkins, L., Treder, M., Liebig, P., Murphy, K. and Kopanoglu, E. 2022. Rigid motion-resolved B1+ prediction using deep learning for real-time parallel-transmission pulse design. Magnetic Resonance in Medicine 87(5), pp. 2254-2270. (10.1002/mrm.29132)
- Kopanoglu, E., Deniz, C. M., Erturk, M. A. and Wise, R. G. 2020. Specific absorption rate implications of within-scan patient head motion for ultra-high field MRI. Magnetic Resonance in Medicine 84(5), pp. 2724-2738. (10.1002/mrm.28276)
- Kopanoglu, E., Gungor, A., Kilic, T., Ulku Saritas, E., Oguz, K. K., Culcur, T. and Guven, H. E. 2020. Simultaneous use of individual and joint regularization terms in compressive sensing: Joint reconstruction of multi-channel multi-contrast MRI acquisitions. NMR in Biomedicine 33(4), article number: e4247. (10.1002/nbm.4247)
- Senel, L. K. et al. 2019. Statistically segregated k-space sampling for accelerating multiple-acquisition MRI. IEEE Transactions on Medical Imaging 38(7), pp. 1701-1714. (10.1109/TMI.2019.2892378)
- Wang, H., Tam, L., Kopanoglu, E., Peters, D. C., Constable, R. T. and Galiana, G. 2017. O-space with high resolution readouts outperforms radial imaging. Magnetic Resonance Imaging 37, pp. 107-115. (10.1016/j.mri.2016.11.012)
- Wang, H., Tam, L., Kopanoglu, E., Peters, D. C., Constable, R. T. and Galiana, G. 2016. Experimental O-space turbo spin echo imaging. Magnetic Resonance in Medicine 75(4), pp. 1654-1661. (10.1002/mrm.25741)
- Kopanoglu, E. and Constable, R. T. 2015. Radiofrequency pulse design using nonlinear gradient magnetic fields. Magnetic Resonance in Medicine 74(3), pp. 826-839. (10.1002/mrm.25423)
- Kopanoglu, E., Yilmaz, U., Gokhalk, Y. and Atalar, E. 2013. Specific absorption rate reduction using nonlinear gradient fields. Magnetic Resonance in Medicine 70(2), pp. 537-546. (10.1002/mrm.24478)
- Turk, E. A., Kopanoglu, E., Guney, S., Bugdayci, K. E., Ider, Y. Z., Erturk, V. B. and Atalar, E. 2012. A simple analytical expression for the gradient induced potential on active implants during MRI. IEEE Transactions on Biomedical Engineering 59(10), pp. 2845-2851. (10.1109/TBME.2012.2212190)
- Kopanoglu, E., Erturk, V. B. and Atalar, E. 2011. Analytic expressions for the ultimate intrinsic signal-to-noise ratio and ultimate intrinsic specific absorption rate in MRI. Magnetic Resonance in Medicine 66(3), pp. 846-858. (10.1002/mrm.22830)
Ymchwil
Diddordebau Ymchwil Cyfredol
Mae fy ymchwil yn canolbwyntio ar Delweddu Cyseiniant Magnetig (MRI). Yn fwy penodol, mae gen i ddiddordeb mewn diogelwch ac ansawdd delwedd yn MRI.
Gall cynnig cleifion achosi i wresogi cleifion gynyddu mwy na 3 gwaith
Mae sgan MRI yn achosi gwres cleifion. Mae'r gwres hwn yn fach iawn a chymerir rhagofalon i sicrhau ei fod yn aros yn is na therfynau diogelwch llym. At y diben hwn, mae efelychiadau cyfrifiadurol yn cael eu perfformio gan ddefnyddio modelau corff realistig (Ffigur 1). Mae'r efelychiadau cyfrifiadurol hyn yn ein helpu i ymchwilio i'r gwres o dan amodau sgan realistig. Yna, gallwn addasu ein protocolau delweddu i sicrhau diogelwch.
Ffigur 1: Defnyddir modelau corff realistig mewn efelychiadau cyfrifiadurol i ymchwilio i ddiogelwch cleifion. Yma, dangosir model y corff ynghyd ag arae trosglwyddo aml-sianel. Mae'r olaf wedi'i fodelu fel 8 coiliau dolen hirsgwar.
Un o'r pynciau rwy'n ymchwilio iddo yw effaith cynnig cleifion ar wresogi. Gall sganiau MRI yn aml bara hyd at awr. Gall nifer o gleifion, gan gynnwys plant yn ogystal ag oedolion, gael trafferth aros yn llonydd yn ystod cyfnodau estynedig o'r fath. Ar ben hynny, gall cleifion â dementia, Parkinson's, Tourette's neu Huntington gael cryndod yn ystod MRI. Pan fydd sefyllfa'r claf yn newid, mae rhyngweithiad y sganiwr â'r claf yn newid. O ganlyniad, gall y patrwm gwresogi newid (Ffigur 2).
Ffigur 2: Mae newid yn sefyllfa'r claf yn effeithio ar wresogi cleifion. Yma, symudodd y man poeth o'r chwith blaen i ran ôl-dde'r ymennydd a daeth yn boethach.
Mae'r Gyfradd Amsugno Penodol (SAR) yn gysylltiedig â gwresogi cleifion, ac fe'i defnyddir yn aml fel paramedr diogelwch yn MRI. Gelwir amrywiad SAR ar draws meinweoedd yn lleol SAR. Rwy'n dylunio curiadau amledd radio realistig a fyddai'n cynhyrchu delwedd o ansawdd uchel. Yna, rwy'n cyfrifo'r dosbarthiad SAR lleol gan ddefnyddio modelau corff realistig. Yn olaf, rwy'n ymchwilio i'r newid mewn SAR lleol rhag ofn y bydd y claf yn symud. Mae Ffigur 3 yn dangos rhanbarthau lle roedd SAR lleol yn uwch na'r uchafbwynt a amcangyfrifwyd i ddechrau oherwydd mudiant cleifion; h.y. lle byddai gwres yn fwy na'r uchafswm amcangyfrifedig.
Ffigur 3: Mae cynnig cleifion yn achosi i'r gwres ddyblu mewn rhanbarth gyda chyfaint o 19 centimetr ciwbig.
Gall sganiau byrrach gynhyrchu delweddau o ansawdd uchel pan fydd delweddau'n cael eu prosesu gyda'i gilydd
Mewn lleoliadau clinigol, defnyddir protocolau delweddu lluosog i ddelweddu claf. Mae'r protocolau delweddu hyn yn cael eu haddasu fel bod pob set delwedd o dan ddylanwad mecanwaith cyferbyniad gwahanol (Ffigur 4). Mae'r delweddau hyn yn darparu gwybodaeth ategol, ac felly, sicrhau'r gwerth diagnostig mwyaf posibl.
Ffigur 4: Mae delweddau a gafwyd o dan ddylanwad gwahanol fecanweithiau cyferbyniad yn darparu gwybodaeth ddiagnostig ategol.
Er mwyn lleihau amser sganio, gellir cyflymu protocolau MRI trwy gaffael llai o ddata. Os bodlonir rhai amodau, gellir digolledu effaith y gostyngiad data hwn trwy brosesu delweddau (Ffigur 5).
Ffigur 5: Pan fydd swm y data a gesglir yn cael ei leihau gan 87.5%, mae ansawdd delwedd yn cael ei effeithio'n drwm (a). Fodd bynnag, gall technegau ailadeiladu aflinol ein helpu i adfer delwedd o ansawdd uchel (b).
Pan fyddwn yn prosesu data caffaeledig, gallwn brosesu gwahanol wrthgyferbyniadau gyda'n gilydd. Mae hyn yn caniatáu rhannu gwybodaeth, ac yn gwella ansawdd delwedd (Ffigur 6). Fodd bynnag, gall y prosesu ar y cyd hwn hefyd achosi effeithiau niweidiol. Yr effaith bwysicaf o'r fath yw gollwng nodweddion sy'n unigryw i ddelwedd i'r delweddau eraill (gollyngiadau-nodweddion, Ffigur 6).
Ffigur 6: Mae prosesu delweddau gyda'i gilydd (b) yn gwella ansawdd delwedd o'i gymharu â phob delwedd sy'n mynd trwy ailadeiladu aflinol ar wahân (a). Fodd bynnag, mae hyn yn arwain at ollwng nodweddion sy'n unigryw i un ddelwedd i'r delweddau eraill (saethau coch). Mae ein dull ailadeiladu arfaethedig yn atal arteffactau gollyngiadau o'r fath ac yn cynhyrchu delweddau o ansawdd uchel di-arteffactau (c). Sylwch fod cyferbyniad y ddelwedd wedi'i addasu i wneud y mwyaf o welededd arteffactau.
Gwnaethom gynnig algorithm ailadeiladu delwedd sy'n prosesu delweddau gyda'i gilydd ac ar wahân. Mae prosesu delweddau gyda'i gilydd yn gwella ansawdd wrth brosesu delweddau ar wahân yn sicrhau bod pob delwedd yn ffyddlon i'w data. Felly, mae'r dull yn cynhyrchu delweddau o ansawdd uchel yn rhydd o ollyngiadau-o-nodweddion (Ffigur 6). Mae delweddau mewn-vivo lle cyflymwyd y sgan gan 87.5% yn dangos y gellir caffael delweddau o ansawdd uchel ar 12.5% o hyd protocol safonol (Ffigur 7).
Ffigur 7: Cafodd delweddau wedi'u pwysoli â dwysedd proton, wedi'u pwysoli T1 a T2 eu prosesu gyda'i gilydd i ail-greu delweddau o ansawdd uchel. Roedd yr holl brotocolau delweddu wedi'u cyflymu 87.5% o'i gymharu â'u fersiynau safonol (ffactor cyflymu R = 8). Dangosodd y dull arfaethedig (SIMIT) gnewyllyn Lentiform (saethau pinc) a'r cortecs opercwlar blaen (saeth felen) yn gliriach. Roedd SIMIT hefyd yn darlunio'r ffiniau mater llwyd yn y sulci yn gliriach yn y delweddau T1 wedi'u pwysoli.
Cafodd y dull arfaethedig (SIMIT) ei werthuso gan niwroradiolegydd. Mae'r sgorau yn tynnu sylw at berfformiad uwch SIMIT o ran gwerth diagnostig (Ffigur 8).
Ffigur 8: Mae sgorau niwroradiolegydd yn tynnu sylw at berfformiad ailadeiladu delwedd gwell SIMIT. Cafodd y niwroradiolegydd ei ddallu i ddull enwau a chyflwynwyd delweddau mewn trefn ar hap.
Grŵp ymchwil
Addysgu
PST 510: Prosiect Ymchwil Niwroddelweddu
PST 512: Cyflwyniad i Ddulliau Niwroddelweddu
PST 513: Dylunio a Dadansoddi Ymchwil mewn Niwroddelweddu
PST514: Cyflwyniad i Ystadegau a Rhaglennu Matlab
PST515: Cynnig Ymchwil Niwroddelweddu
Bywgraffiad
Addysg
- 2012: PhD mewn Peirianneg Drydanol ac Electroneg . Prifysgol Bilkent, Ankara, Twrci. Technegau Nofel ynghylch Cyfradd Amsugno Penodol a Maes Golwg Lleihau mewn Delweddu Cyseiniant Magnetig
- 2006: BSc mewn Peirianneg Drydanol ac Electroneg . Prifysgol Bilkent, Ankara, Twrci.
Cyflogaeth
- 2017 – presennol: Darlithydd mewn Seicoleg. Prifysgol Caerdydd, Caerdydd, y DU.
- 2015 – 2017: Uwch Wyddonydd Ymchwil. Canolfan Ymchwil Aselsan, Ankara, Twrci.
- 2012 – 2015: Cyswllt Ôl-ddoethurol. Radioleg a Delweddu Biofeddygol. Prifysgol Yale, New Haven, CT, UDA.
- 2006 – 2012: Cynorthwy-ydd Ymchwil ac Addysgu. Peirianneg drydanol ac electroneg. Prifysgol Bilkent, Ankara, Twrci.
- 2006 – 2006: Cynorthwyydd Addysgu Israddedig. Peirianneg drydanol ac electroneg. Prifysgol Bilkent, Ankara, Twrci.
Pwyllgorau ac adolygu
Profiad y Pwyllgor
- 2021 – presennol: Cadeirydd, MRI Pwyllgor Diogelwch y Gymdeithas Ryngwladol ar gyfer Cyseiniant Magnetig mewn Meddygaeth.
- 2021 – presennol: Aelod, Pwyllgor Datblygu Gwe y Gymdeithas Ryngwladol ar gyfer Cyseiniant Magnetig mewn Meddygaeth.
- 2020 – presennol: Aelod, MRI Pwyllgor Diogelwch y Gymdeithas Ryngwladol ar gyfer Cyseiniant Magnetig mewn Meddygaeth.
Profiad adolygu
Dyddlyfr
- Cyseiniant Magnetig mewn Meddygaeth
- NMR mewn Biofeddygaeth
- Prosesu Signalau, Delwedd a Fideo
- Journal of Peirianneg Feddygol a Biolegol
- Gwyddorau Cymhwysol
- Turkish Journal of Peirianneg Drydanol a Gwyddorau Cyfrifiadurol
- PloS One
Cynhadledd
- Cyfarfod Blynyddol ISMRM
- Cyfarfod Pennod Prydain ac Iwerddon ISMRM
Panel cyllido
- Arloesi i Bawb – Prifysgol Caerdydd
- Cronfa Cymorth Strategol Sefydliadol Ymddiriedolaeth Wellcome – Prifysgol Caerdydd
Meysydd goruchwyliaeth
Goruchwyliaeth gyfredol
Luke Watkins
Myfyriwr ymchwil
Katya Blanter
Myfyriwr ymchwil
Contact Details
+44 29225 10256
Ysgol Seicoleg, Ystafell CUBRIC 1.016, Plas y Parc, Caerdydd, CF10 3AT