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Dr Emre Kopanoglu
- Ar gael fel goruchwyliwr ôl-raddedig
Timau a rolau for Emre Kopanoglu
Uwch Ddarlithydd
Trosolwyg
Crynodeb ymchwil
Mae Delweddu Cyseiniant Magnetig yn ddull delweddu pwerus gyda gwrthgyferbyniad meinwe meddal uchel, diogelwch cynhenid oherwydd diffyg ymbelydredd ïoneiddio, a chymhareb signal-i-sŵn sy'n ddigonol yn ddiagnostig. Nod fy ymchwil yw gwella ansawdd delweddau diagnostig yn ogystal â chysur a diogelwch cleifion mewn MRI, ac mae'n cynnwys prosesu signalau / delwedd, modelu cyfrifiadurol, a chaledwedd delweddu newydd.
Gyda llawer o sganiau MRI yn para sawl munud, mae symudiad cleifion yn broblem ddifrifol. Os nad yw'n cael ei gywiro mewn amser real, mae llawer o batrymau cynnig yn newid y gyfrol ddelwedd, ac felly yn gwneud data delweddu anghyson ac yn golygu bod angen ail-sganio'r claf. Ar y naill law, ar gryfderau maes isaf, gall technegau cywiro cynnig amser real (rhagolygol) addasu'r cyfaint delweddu mewn amser real. Fodd bynnag, mae cryfderau maes is yn golygu cymhareb signal-i-sŵn is a chymhareb cyferbyniad-i-sŵn, hy ansawdd delwedd is. Ar y llaw arall, mae MRI maes ultra-uchel (UHF, >3T) yn cynnig llawer o fanteision o ran ansawdd a chyferbyniad delwedd. Yn anffodus, mae MRI UHF yn dioddef o amrywiadau cyferbyniad annymunol ar draws y ddelwedd. Er y gellir digolledu amrywiadau o'r fath am ddefnyddio curiadau amledd radio wedi'u teilwra a systemau trosglwyddo aml-sianel (trosglwyddo cyfochrog), mae dylunio corbys o'r fath yn cymryd o fwy na sawl eiliad i ychydig funudau gyda llawer o algorithmau. Felly, nid yw cywiro cynnig amser real wedi bod yn bosibl eto gyda chorbys o'r fath. Mae fy ymchwil cyfredol yn canolbwyntio ar ddylunio curiadau trosglwyddo cyfochrog mewn amser real.
Cyhoeddiad
2026
- Blanter, K. A. et al. 2026. Using U‐Nets to predict the effects of head motion on simulated specific absorption rate for ultra‐high field magnetic resonance imaging with parallel transmission. Magnetic Resonance in Medicine 96 (2), pp.650-665. (10.1002/mrm.70363)
- Royer, W. et al. 2026. Repeatable tract-based diffusion metrics on a portable 64 mT MRI: a foundation for global population neuroscience. Frontiers in Neuroimaging 5 1845201. (10.3389/fnimg.2026.1845201)
- Kopanoglu, E. , Atalar, E. and Constable, R. T. 2026. SAR-efficient sub-volume imaging using nonlinear gradient magnetic fields. Journal of Imaging 12 (6) 261. (10.3390/jimaging12060261)
- Kopanoglu, E. et al. 2026. MRI and implant safety at low-field and ultralow-field strengths. Journal of Magnetic Resonance Imaging 63 (2), pp.364-377. (10.1002/jmri.70168)
2025
- Jones, D. K. et al. 2025. Low field, high impact: Democratizing MRI for clinical and research innovation. BJR Open 7 (1) tzaf022. (10.1093/bjro/tzaf022)
- Blanter, K. A. et al. 2025. Evaluating rigid motion-affected, U-NET-estimated Q-matrices with parallel RF transmission. Presented at: 2025 ISMRM & ISMRT Annual Meeting & Exhibition Honolulu, Hawaii, USA 10-15 May, 2025. Proceedings of the International Society for Magnetic Resonance in Medicine - Scientific Meeting and Exhibition. , pp.1322. (10.58530/2025/1322)
2024
- Blanter, K. , Plumley, A. and Kopanoglu, E. 2024. The effects of simulated SAR data processing methods and network parameter tuning on gridding artifacts and network estimation accuracy. Presented at: 2024 ISMRM & ISMRT Annual Meeting & Exhibition Singapore 4-9 May 2024. ISMRM & ISMRT Annual Meeting. , pp.3802. (10.58530/2024/3802)
- Blanter, K. et al. 2024. Estimating variations in SAR calculations due to within-scan patient motion using cGANs for parallel RF transmission at ultrahigh field MRI. Presented at: 2024 ISMRM & ISMRT Annual Meeting & Exhibition Singapore 4-9 May, 2024. ISMRM & ISMRT Annual Meeting. , pp.0468. (10.58530/2024/0468)
2023
- Blanter, K. et al. 2023. Towards applying deep learning to predict rigid motion-induced changes in Q-matrices from UHF-MRI pTx simulations. Presented at: 2023 ISMRM & ISMRT Annual Meeting & Exhibition Toronto, Canada 3-8 June 2023.
- Kopanoglu, E. 2023. Actual patient position versus safety models: specific absorption rate implications of initial head position at ultrahigh field MRI. NMR in Biomedicine 36 (5) e4876. (10.1002/nbm.4876)
2022
- Collins, J. D. et al., 2022. Magnetic resonance imaging during a pandemic: recommendations by the ISMRM safety committee. Journal of Magnetic Resonance Imaging 55 (5), pp.1322-1339. (10.1002/jmri.28006)
- Plumley, A. et al. 2022. Rigid motion-resolved B1+ prediction using deep learning for real-time parallel-transmission pulse design. Magnetic Resonance in Medicine 87 (5), pp.2254-2270. (10.1002/mrm.29132)
- Kopanoglu, E. 2022. Head position related SAR uncertainty depends on slice orientation and pulse complexity. Presented at: Joint Annual Meeting ISMRM-ESMRMB London, UK 07-12 May 2022. Proceedings of the Joint Annual Meeting ISMRM-ESMRMB. Vol. 2870.
2021
- Gholam, J. A. et al. 2021. aDWI-BIDS: advanced diffusion weighted imaging metadata for the brain imaging data structure. Presented at: ISMRM & SMRT Annual Meeting & Exhibition Virtual 15-20 May 2021.
- Kopanoglu, E. 2021. Patient specific parallel transmit pulses are patient position dependent while safety models are fixed: safety implications. Presented at: 2021 ISMRM & SMRT Annual Meeting & Exhibition Virtual 15-20 May 2021.
- Plumley, A. , Schmid, P. and Kopanoglu, E. 2021. Parallel transmit coil dimensions affect SAR sensitivity to motion at 7T. Presented at: ISMRM & SMRT Annual Meeting & Exhibition Virtual 15-20 May 2021.
- Plumley, A. et al. 2021. Motion-resolved B1+ prediction using deep learning for real-time pTx pulse-design. Presented at: ISMRM & SMRT Annual Meeting & Exhibition Virtual 15-20 May 2021.
- Watkins, L. et al., 2021. Motion robust parallel transmission excitation pulse design for ultra-high field MRI [Abstract]. Presented at: 2021 ISMRM & SMRT Annual Meeting & Exhibition Virtual 15-20 May 2021. ISMRM Proceedings.
2020
- Kopanoglu, E. et al. 2020. Specific absorption rate implications of within-scan patient head motion for ultra-high field MRI. Magnetic Resonance in Medicine 84 (5), pp.2724-2738. (10.1002/mrm.28276)
- Kopanoglu, E. , Deniz, C. M. and Wise, R. G. 2020. Simultaneous multi-slice imaging reduces sensitivity of local-SAR to patient motion at 7T. Presented at: ISMRM 28th Annual Meeting & Exhibition Sydney Australia 08-14 August 2020. Proceedings of the ISMRM 28th annual meeting and exhibition. Vol. 3691.
- Kopanoglu, E. et al. 2020. Simultaneous use of individual and joint regularization terms in compressive sensing: Joint reconstruction of multi-channel multi-contrast MRI acquisitions. NMR in Biomedicine 33 (4) e4247. (10.1002/nbm.4247)
- Plumley, A. , Watkins, L. and Kopanoglu, E. 2020. Large tip-angle, motion robust pulse design for parallel transmission at 7T using composite B1 distributions. Presented at: ISMRM & SMRT Virtual Conference & Exhibition 2020 Online 8-14 August 2020.
- Watkins, L. et al., 2020. Motion robust parallel transmission excitation pulse design for ultra-high field MRI. Presented at: ISMRM & SMRT Virtual Conference & Exhibition 2020 Online 8-14 August 2020.
2019
- Senel, L. K. et al., 2019. Statistically segregated k-space sampling for accelerating multiple-acquisition MRI. IEEE Transactions on Medical Imaging 38 (7), pp.1701-1714. (10.1109/TMI.2019.2892378)
- Kopanoglu, E. et al. 2019. Multi-channel multi-contrast reconstructions via simultaneous use of individual and joint regularization terms. Presented at: ISMRM 27th Annual Meeting & Exhibition Montréal, QC, Canada 11-16 May 2019. Proceedings of the ISMRM 27th Annual Meeting and Exhibition. ISMRM. , pp.4748.
- Kopanoglu, E. et al. 2019. Random RF shimming may conceal possible local SAR hotspots for asymmetric parallel transmit coils. Presented at: ISMRM 27th Annual Meeting & Exhibition Montréal, QC, Canada 11-16 May 2019. Proceedings of the ISMRM 27th Annual Meeting and Exhibition. ISMRM. , pp.4158.
- Kopanoglu, E. et al. 2019. Implications of within-scan patient head motion on B1+ homogeneity and specific absorption rate at 7T. Presented at: ISMRM 27th Annual Meeting & Exhibition Montréal, QC, Canada 11-16 May 2019. Proceedings of the ISMRM 27th annual meeting and exhibition. Vol. 4686.
2018
- Kopanoglu, E. 2018. Near real-time parallel-transmit pulse design. Presented at: Joint Annual Meeting ISMRM-ESMRMB 2018 Paris, France 16-21 June 2018. Proceedings of the Joint ISMRM - ESMRMB Meeting. , pp.3392.
- Kopanoglu, E. et al. 2018. Compressive sensing reconstruction for multi-contrast data with unequal acceleration rates. Presented at: Joint Annual Meeting ISMRM-ESMRMB 2018 Paris, France 16-21 June 2018. Proceedings of the Joint Annual Meeting ISMRM-ESMRMB 2018. , pp.3534.
2017
- Gungor, A. et al., 2017. A synthesis-based approach to compressive multi-contrast magnetic resonance imaging. Presented at: IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017) Melbourne, Australia 18-21 Apr 2017. IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017). IEEE(10.1109/ISBI.2017.7950615)
- Wang, H. et al., 2017. O-space with high resolution readouts outperforms radial imaging. Magnetic Resonance Imaging 37 , pp.107-115. (10.1016/j.mri.2016.11.012)
- Styner, M. A. et al., 2017. Fast recovery of compressed multi-contrast magnetic resonance images. Presented at: Medical Imaging 2017: Image Processing Orlando, FL, USA 11 February 2017. Proc. SPIE 10133, Medical Imaging 2017: Image Processing. Vol. 10133.Society of Photo-optical Instrumentation Engineers. , pp.101331R. (10.1117/12.2252101)
- Kopanoglu, E. et al. 2017. Joint reconstruction of multi-contrast images: compressive sensing reconstruction using both joint and individual regularization functions. Presented at: ISMRM 25th Annual Meeting & Exhibition SMRT 26th Annual Meeting Honolulu, HI, USA 22-27 April 2017. Proceedings of the 25th ISMRM 25th Annual Meeting & Exhibition. , pp.3875.
2016
- Gungor, A. et al., 2016. Compressed multi-contrast magnetic resonance image reconstruction using augmented lagrangian method. Presented at: 2016 24th Signal Processing and Communication Application Conference (SIU) Zonguldak, Turkey 16-19 May 2016. 2016 24th Signal Processing and Communication Application Conference (SIU). IEEE(10.1109/SIU.2016.7496157)
- Kopanoglu, E. et al. 2016. Motion tracking using nonlinear gradient fields: experimental verification and oblique slices. Presented at: ISMRM 24th Annual Meeting & Exhibition Singapore 07-13 May 2016. Proceedings of the ISMRM 24th annual meeting and exhibition.
- Kopanoglu, E. et al. 2016. Accelerated imaging of sub-volumes using region-of-interest focused O-Space: experimental verification of rOi-Space. Presented at: ISMRM 24th Annual Meeting & Exhibition Singapore 07-13 May 2016. Proceedings of the ISMRM 24th annual meeting and exhibition.
- Wang, H. et al., 2016. Low-Rank O-Space Reconstruction. Presented at: ISMRM 24th Annual Meeting & Exhibition Singapore 07-13 May 2016.
- Wang, H. et al., 2016. Experimental O-space turbo spin echo imaging. Magnetic Resonance in Medicine 75 (4), pp.1654-1661. (10.1002/mrm.25741)
2015
- Kopanoglu, E. and Constable, R. T. 2015. Radiofrequency pulse design using nonlinear gradient magnetic fields. Magnetic Resonance in Medicine 74 (3), pp.826-839. (10.1002/mrm.25423)
- Kopanoglu, E. , Galiana, G. and Constable, R. T. 2015. Motion navigation using non-linear gradient fields. Presented at: ISMRM 23rd Annual Meeting & Exhibition Toronto, Ontario, Canada 30 May-5 June 2015. Proceedings of the ISMRM 23rd annual meeting and exhibition.
- Kopanoglu, E. et al. 2015. rOi-Space: accelerated imaging of sub-volumes using ROI focused O-Space. Presented at: ISMRM 23rd Annual Meeting & Exhibition Toronto, Ontario, Canada 30 May-5 June 2015. Proceedings of the ISMRM 23rd annual meeting and exhibition.
2014
- Wang, H. et al., 2014. Accelerate data acquisition using Turbo Spin Echo and O-Space. Presented at: 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI) 29 April - 2 May 2014. Biomedical Imaging (ISBI), 2014 IEEE 11th International Symposium on. IEEE. , pp.874-877. (10.1109/ISBI.2014.6868010)
2013
- Kopanoglu, E. et al. 2013. Specific absorption rate reduction using nonlinear gradient fields. Magnetic Resonance in Medicine 70 (2), pp.537-546. (10.1002/mrm.24478)
2012
- Turk, E. A. et al., 2012. A simple analytical expression for the gradient induced potential on active implants during MRI. IEEE Transactions on Biomedical Engineering 59 (10), pp.2845-2851. (10.1109/TBME.2012.2212190)
2011
- Kopanoglu, E. , Erturk, V. B. and Atalar, E. 2011. Analytic expressions for the ultimate intrinsic signal-to-noise ratio and ultimate intrinsic specific absorption rate in MRI. Magnetic Resonance in Medicine 66 (3), pp.846-858. (10.1002/mrm.22830)
Cynadleddau
- Blanter, K. A. et al. 2025. Evaluating rigid motion-affected, U-NET-estimated Q-matrices with parallel RF transmission. Presented at: 2025 ISMRM & ISMRT Annual Meeting & Exhibition Honolulu, Hawaii, USA 10-15 May, 2025. Proceedings of the International Society for Magnetic Resonance in Medicine - Scientific Meeting and Exhibition. , pp.1322. (10.58530/2025/1322)
- Blanter, K. , Plumley, A. and Kopanoglu, E. 2024. The effects of simulated SAR data processing methods and network parameter tuning on gridding artifacts and network estimation accuracy. Presented at: 2024 ISMRM & ISMRT Annual Meeting & Exhibition Singapore 4-9 May 2024. ISMRM & ISMRT Annual Meeting. , pp.3802. (10.58530/2024/3802)
- Blanter, K. et al. 2024. Estimating variations in SAR calculations due to within-scan patient motion using cGANs for parallel RF transmission at ultrahigh field MRI. Presented at: 2024 ISMRM & ISMRT Annual Meeting & Exhibition Singapore 4-9 May, 2024. ISMRM & ISMRT Annual Meeting. , pp.0468. (10.58530/2024/0468)
- Blanter, K. et al. 2023. Towards applying deep learning to predict rigid motion-induced changes in Q-matrices from UHF-MRI pTx simulations. Presented at: 2023 ISMRM & ISMRT Annual Meeting & Exhibition Toronto, Canada 3-8 June 2023.
- Kopanoglu, E. 2022. Head position related SAR uncertainty depends on slice orientation and pulse complexity. Presented at: Joint Annual Meeting ISMRM-ESMRMB London, UK 07-12 May 2022. Proceedings of the Joint Annual Meeting ISMRM-ESMRMB. Vol. 2870.
- Gholam, J. A. et al. 2021. aDWI-BIDS: advanced diffusion weighted imaging metadata for the brain imaging data structure. Presented at: ISMRM & SMRT Annual Meeting & Exhibition Virtual 15-20 May 2021.
- Kopanoglu, E. 2021. Patient specific parallel transmit pulses are patient position dependent while safety models are fixed: safety implications. Presented at: 2021 ISMRM & SMRT Annual Meeting & Exhibition Virtual 15-20 May 2021.
- Plumley, A. , Schmid, P. and Kopanoglu, E. 2021. Parallel transmit coil dimensions affect SAR sensitivity to motion at 7T. Presented at: ISMRM & SMRT Annual Meeting & Exhibition Virtual 15-20 May 2021.
- Plumley, A. et al. 2021. Motion-resolved B1+ prediction using deep learning for real-time pTx pulse-design. Presented at: ISMRM & SMRT Annual Meeting & Exhibition Virtual 15-20 May 2021.
- Watkins, L. et al., 2021. Motion robust parallel transmission excitation pulse design for ultra-high field MRI [Abstract]. Presented at: 2021 ISMRM & SMRT Annual Meeting & Exhibition Virtual 15-20 May 2021. ISMRM Proceedings.
- Kopanoglu, E. , Deniz, C. M. and Wise, R. G. 2020. Simultaneous multi-slice imaging reduces sensitivity of local-SAR to patient motion at 7T. Presented at: ISMRM 28th Annual Meeting & Exhibition Sydney Australia 08-14 August 2020. Proceedings of the ISMRM 28th annual meeting and exhibition. Vol. 3691.
- Plumley, A. , Watkins, L. and Kopanoglu, E. 2020. Large tip-angle, motion robust pulse design for parallel transmission at 7T using composite B1 distributions. Presented at: ISMRM & SMRT Virtual Conference & Exhibition 2020 Online 8-14 August 2020.
- Watkins, L. et al., 2020. Motion robust parallel transmission excitation pulse design for ultra-high field MRI. Presented at: ISMRM & SMRT Virtual Conference & Exhibition 2020 Online 8-14 August 2020.
- Kopanoglu, E. et al. 2019. Multi-channel multi-contrast reconstructions via simultaneous use of individual and joint regularization terms. Presented at: ISMRM 27th Annual Meeting & Exhibition Montréal, QC, Canada 11-16 May 2019. Proceedings of the ISMRM 27th Annual Meeting and Exhibition. ISMRM. , pp.4748.
- Kopanoglu, E. et al. 2019. Random RF shimming may conceal possible local SAR hotspots for asymmetric parallel transmit coils. Presented at: ISMRM 27th Annual Meeting & Exhibition Montréal, QC, Canada 11-16 May 2019. Proceedings of the ISMRM 27th Annual Meeting and Exhibition. ISMRM. , pp.4158.
- Kopanoglu, E. et al. 2019. Implications of within-scan patient head motion on B1+ homogeneity and specific absorption rate at 7T. Presented at: ISMRM 27th Annual Meeting & Exhibition Montréal, QC, Canada 11-16 May 2019. Proceedings of the ISMRM 27th annual meeting and exhibition. Vol. 4686.
- Kopanoglu, E. 2018. Near real-time parallel-transmit pulse design. Presented at: Joint Annual Meeting ISMRM-ESMRMB 2018 Paris, France 16-21 June 2018. Proceedings of the Joint ISMRM - ESMRMB Meeting. , pp.3392.
- Kopanoglu, E. et al. 2018. Compressive sensing reconstruction for multi-contrast data with unequal acceleration rates. Presented at: Joint Annual Meeting ISMRM-ESMRMB 2018 Paris, France 16-21 June 2018. Proceedings of the Joint Annual Meeting ISMRM-ESMRMB 2018. , pp.3534.
- Gungor, A. et al., 2017. A synthesis-based approach to compressive multi-contrast magnetic resonance imaging. Presented at: IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017) Melbourne, Australia 18-21 Apr 2017. IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017). IEEE(10.1109/ISBI.2017.7950615)
- Styner, M. A. et al., 2017. Fast recovery of compressed multi-contrast magnetic resonance images. Presented at: Medical Imaging 2017: Image Processing Orlando, FL, USA 11 February 2017. Proc. SPIE 10133, Medical Imaging 2017: Image Processing. Vol. 10133.Society of Photo-optical Instrumentation Engineers. , pp.101331R. (10.1117/12.2252101)
- Kopanoglu, E. et al. 2017. Joint reconstruction of multi-contrast images: compressive sensing reconstruction using both joint and individual regularization functions. Presented at: ISMRM 25th Annual Meeting & Exhibition SMRT 26th Annual Meeting Honolulu, HI, USA 22-27 April 2017. Proceedings of the 25th ISMRM 25th Annual Meeting & Exhibition. , pp.3875.
- Gungor, A. et al., 2016. Compressed multi-contrast magnetic resonance image reconstruction using augmented lagrangian method. Presented at: 2016 24th Signal Processing and Communication Application Conference (SIU) Zonguldak, Turkey 16-19 May 2016. 2016 24th Signal Processing and Communication Application Conference (SIU). IEEE(10.1109/SIU.2016.7496157)
- Kopanoglu, E. et al. 2016. Motion tracking using nonlinear gradient fields: experimental verification and oblique slices. Presented at: ISMRM 24th Annual Meeting & Exhibition Singapore 07-13 May 2016. Proceedings of the ISMRM 24th annual meeting and exhibition.
- Kopanoglu, E. et al. 2016. Accelerated imaging of sub-volumes using region-of-interest focused O-Space: experimental verification of rOi-Space. Presented at: ISMRM 24th Annual Meeting & Exhibition Singapore 07-13 May 2016. Proceedings of the ISMRM 24th annual meeting and exhibition.
- Wang, H. et al., 2016. Low-Rank O-Space Reconstruction. Presented at: ISMRM 24th Annual Meeting & Exhibition Singapore 07-13 May 2016.
- Kopanoglu, E. , Galiana, G. and Constable, R. T. 2015. Motion navigation using non-linear gradient fields. Presented at: ISMRM 23rd Annual Meeting & Exhibition Toronto, Ontario, Canada 30 May-5 June 2015. Proceedings of the ISMRM 23rd annual meeting and exhibition.
- Kopanoglu, E. et al. 2015. rOi-Space: accelerated imaging of sub-volumes using ROI focused O-Space. Presented at: ISMRM 23rd Annual Meeting & Exhibition Toronto, Ontario, Canada 30 May-5 June 2015. Proceedings of the ISMRM 23rd annual meeting and exhibition.
- Wang, H. et al., 2014. Accelerate data acquisition using Turbo Spin Echo and O-Space. Presented at: 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI) 29 April - 2 May 2014. Biomedical Imaging (ISBI), 2014 IEEE 11th International Symposium on. IEEE. , pp.874-877. (10.1109/ISBI.2014.6868010)
Erthyglau
- Blanter, K. A. et al. 2026. Using U‐Nets to predict the effects of head motion on simulated specific absorption rate for ultra‐high field magnetic resonance imaging with parallel transmission. Magnetic Resonance in Medicine 96 (2), pp.650-665. (10.1002/mrm.70363)
- Royer, W. et al. 2026. Repeatable tract-based diffusion metrics on a portable 64 mT MRI: a foundation for global population neuroscience. Frontiers in Neuroimaging 5 1845201. (10.3389/fnimg.2026.1845201)
- Kopanoglu, E. , Atalar, E. and Constable, R. T. 2026. SAR-efficient sub-volume imaging using nonlinear gradient magnetic fields. Journal of Imaging 12 (6) 261. (10.3390/jimaging12060261)
- Kopanoglu, E. et al. 2026. MRI and implant safety at low-field and ultralow-field strengths. Journal of Magnetic Resonance Imaging 63 (2), pp.364-377. (10.1002/jmri.70168)
- Jones, D. K. et al. 2025. Low field, high impact: Democratizing MRI for clinical and research innovation. BJR Open 7 (1) tzaf022. (10.1093/bjro/tzaf022)
- Kopanoglu, E. 2023. Actual patient position versus safety models: specific absorption rate implications of initial head position at ultrahigh field MRI. NMR in Biomedicine 36 (5) e4876. (10.1002/nbm.4876)
- Collins, J. D. et al., 2022. Magnetic resonance imaging during a pandemic: recommendations by the ISMRM safety committee. Journal of Magnetic Resonance Imaging 55 (5), pp.1322-1339. (10.1002/jmri.28006)
- Plumley, A. et al. 2022. Rigid motion-resolved B1+ prediction using deep learning for real-time parallel-transmission pulse design. Magnetic Resonance in Medicine 87 (5), pp.2254-2270. (10.1002/mrm.29132)
- Kopanoglu, E. et al. 2020. Specific absorption rate implications of within-scan patient head motion for ultra-high field MRI. Magnetic Resonance in Medicine 84 (5), pp.2724-2738. (10.1002/mrm.28276)
- Kopanoglu, E. et al. 2020. Simultaneous use of individual and joint regularization terms in compressive sensing: Joint reconstruction of multi-channel multi-contrast MRI acquisitions. NMR in Biomedicine 33 (4) e4247. (10.1002/nbm.4247)
- Senel, L. K. et al., 2019. Statistically segregated k-space sampling for accelerating multiple-acquisition MRI. IEEE Transactions on Medical Imaging 38 (7), pp.1701-1714. (10.1109/TMI.2019.2892378)
- Wang, H. et al., 2017. O-space with high resolution readouts outperforms radial imaging. Magnetic Resonance Imaging 37 , pp.107-115. (10.1016/j.mri.2016.11.012)
- Wang, H. et al., 2016. Experimental O-space turbo spin echo imaging. Magnetic Resonance in Medicine 75 (4), pp.1654-1661. (10.1002/mrm.25741)
- Kopanoglu, E. and Constable, R. T. 2015. Radiofrequency pulse design using nonlinear gradient magnetic fields. Magnetic Resonance in Medicine 74 (3), pp.826-839. (10.1002/mrm.25423)
- Kopanoglu, E. et al. 2013. Specific absorption rate reduction using nonlinear gradient fields. Magnetic Resonance in Medicine 70 (2), pp.537-546. (10.1002/mrm.24478)
- Turk, E. A. et al., 2012. A simple analytical expression for the gradient induced potential on active implants during MRI. IEEE Transactions on Biomedical Engineering 59 (10), pp.2845-2851. (10.1109/TBME.2012.2212190)
- Kopanoglu, E. , Erturk, V. B. and Atalar, E. 2011. Analytic expressions for the ultimate intrinsic signal-to-noise ratio and ultimate intrinsic specific absorption rate in MRI. Magnetic Resonance in Medicine 66 (3), pp.846-858. (10.1002/mrm.22830)
Ymchwil
Diddordebau Ymchwil Cyfredol
Mae fy ymchwil yn canolbwyntio ar Delweddu Cyseiniant Magnetig (MRI). Yn fwy penodol, mae gen i ddiddordeb mewn diogelwch ac ansawdd delwedd mewn MRI.
Gall cynnig pwnc achosi i wresogi pwnc gynyddu mwy na 3 gwaith
Mae sgan MRI yn achosi gwresogi meinwe. Mae'r gwresogi hwn yn lleiaf ac mae rhagofalon yn cael eu cymryd i sicrhau ei fod yn aros yn is na terfynau diogelwch llym. Oherwydd na ellir mesur gwresogi meinwe gwirioneddol yn gyflym in vivo, defnyddir modelu cyfrifiadurol. Er mwyn cyfyngu ar wresogi meinwe, defnyddir paramedr dirprwyol, o'r enw Cyfradd Amsugno Penodol (SAR). Gelwir dosbarthiad SAR yn y gofod a'r gwerth uchaf yn SAR lleol, a SAR lleol brig, yn y drefn honno.
Pan fydd y pwnc yn symud yn ystod y sgan, gall SAR gynyddu'n sylweddol. Dangosodd ein hymchwiliadau gynnydd mwy na 3 gwaith yn SAR lleol brig oherwydd symudiad y pwnc. Achos enghreifftiol : Ffigur 1. Mwy o fanylion: https://doi.org/10.1002/mrm.28276.
Ffigur 1: Subject motion during the scan (20 mm rightward) caused peak local SAR to increase more than 3-fold. Results shown for a computational 8-channel parallel-transmit array tuned for 7T.
Nid yw hon yn broblem ar wahân i achosion pan na all y pwnc aros yn llonydd. Mae lleoliad cychwynnol y pwnc hefyd yn cael effaith sylweddol ar SAR lleol brig. Pan dybir bod y pwnc yn y canol ond wedi'i leoli mewn mannau eraill, gellir tanamcangyfrif SAR fwy na phum gwaith. Enghraifft o achos: Ffigur 2. Mwy o fanylion: https://doi.org/10.1002/nbm.4876.
Ffigur 2: Hyd yn oed gyda gwybodaeth berffaith o'r cynnwys meinwe, gall anghysondeb rhwng sefyllfa pwnc tybiedig a gwirioneddol achosi tanamcangyfrif SAR sylweddol. Canlyniadau a ddangosir ar gyfer arae trosglwyddo cyfochrog 8-sianel gyfrifiadurol wedi'i diwnio ar gyfer 7T.
Mae atal cynnydd SAR sy'n gysylltiedig â symudiad yn gofyn am ymylon diogelwch mawr iawn, sy'n lleihau perfformiad delweddu yn sylweddol, gan wneud sganiau MRI yn llawer hirach. Fel arall, gellir addasu cyfrifiadau i symudiad pwnc mewn amser real. Mae hyn yn dibynnu ar ddau amod:
1- Mae'r newid yn y ffordd y mae elfennau coil yn rhyngweithio â meinweoedd yn hysbys. Mae'r rhyngweithio hwn yn arwain at SAR.
2- Gellir perfformio newidiadau i'r pwls amledd radio mewn amser real.
Rydym wedi dangos y gellir defnyddio Rhwydweithiau Niwral Artiffisial (yma, U-Nets) i amcangyfrif sut mae SAR yn newid yn ddibynadwy, mewn llai na 0.2 eiliad o amser cyfrifo. Achos enghreifftiol : Ffigur 3. Mwy o fanylion: https://doi.org/10.1002/mrm.70363.
Ffigur 3: Pan fydd y pwnc yn symud i ffwrdd o'i safle cychwynnol, mae'r SAR lleol brig yn cael ei danamcangyfrif gan 31% (ground-truth: peak gwirioneddol, cychwynnol: amcangyfrifir gan ddefnyddio model diogelwch wedi'i leoli yn y canol). Gall U-Nets adfer y SAR lleol brig gwirioneddol gyda llai na 2% gwall. Canlyniadau a ddangosir ar gyfer pwls realistig sy'n cyffroi slice homogenaidd, gan ddefnyddio arae trosglwyddo cyfochrog 8-sianel gyfrifiadurol wedi'i diwnio ar gyfer 7T.
Gall cynnig pwnc achosi anghysondebau data sy'n gysylltiedig â chyffroi
Mae symudiad y pwnc hefyd yn effeithio ar sensitifrwydd y coil y tu mewn i'r meinweoedd. Mae hyn yn arwain at ddirywiad homogenedd cyffroi, gan greu amrywiadau cyferbyniad artiffisial ar y ddelwedd. Nid yw'r amrywiadau hyn yn gysylltiedig â'r meinwe, ac felly, yn lleihau gwerth diagnostig. Rydym hefyd wedi defnyddio Rhwydweithiau Niwral Artiffisial (yma, cGANs) i amcangyfrif y newidiadau mewn sensitifrwydd coil, sy'n galluogi gwella homogenedd cyffroi wrth i symudiad y pwnc ddigwydd. Achos enghreifftiol : Ffigur 4. Mwy o fanylion: https://doi.org/10.1002/mrm.29132.
Ffigur 4: Dangosir effaith symudiad ar sensitifrwydd coil. Gall y rhwydweithiau amcangyfrif effaith symudiad ar sensitifrwydd coil yn ddibynadwy. Canlyniadau a ddangosir ar gyfer arae trosglwyddo cyfochrog 8-sianel gyfrifiadurol wedi'i diwnio ar gyfer 7T.
Gall sganiau byrrach gynhyrchu delweddau o ansawdd uchel pan fydd delweddau'n cael eu prosesu gyda'i gilydd
Mewn lleoliadau clinigol, defnyddir protocolau delweddu lluosog i ddelweddu pwnc. Mae'r protocolau delweddu hyn yn cael eu haddasu fel bod pob set delweddau o dan ddylanwad mecanwaith cyferbyniad gwahanol (Ffigur 5). Mae'r delweddau hyn yn darparu gwybodaeth gyflenwol, ac felly, yn gwneud y mwyaf o werth diagnostig.
Ffigur 5: Mae delweddau a gafwyd o dan ddylanwad gwahanol fecanweithiau cyferbyniad yn darparu gwybodaeth ddiagnostig gyflenwol.
Er mwyn lleihau amser sganio, gellir cyflymu protocolau MRI trwy gaffael llai o ddata. Os bodlonir amodau penodol, gellir gwneud iawn am effaith y gostyngiad data hwn trwy brosesu delweddau. Pan fyddwn yn prosesu data a gafwyd, gallwn brosesu gwahanol gyferbyniadau gyda'i gilydd. Mae hyn yn caniatáu rhannu gwybodaeth, ac yn gwella ansawdd y ddelwedd (Ffigur 7). Fodd bynnag, gall y prosesu ar y cyd hwn hefyd achosi effeithiau niweidiol, megis gollwng nodweddion sy'n unigryw i ddelwedd i'r delweddau eraill (gollwng nodweddion, Ffigur 6).
Ffigur 6: Prosesu delweddau gyda'i gilydd (b) yn gwella ansawdd delwedd o'i gymharu â phob delwedd sy'n mynd trwy ailadeiladu aflinol ar wahân (a). Fodd bynnag, mae hyn yn arwain at ollwng nodweddion sy'n unigryw i un ddelwedd i'r delweddau eraill (saethau coch). Mae ein dull ailadeiladu arfaethedig yn atal arteffactau gollyngiadau o'r fath ac yn cynhyrchu delweddau o ansawdd uchel heb arteffactau (c). Sylwch fod y cyferbyniad delwedd wedi'i addasu i wneud y mwyaf o welededd arteffactau.
Rydym yn cynnig algorithm ailadeiladu delweddau sy'n prosesu delweddau gyda'i gilydd ac ar wahân. Mae prosesu delweddau gyda'i gilydd yn gwella ansawdd tra bod prosesu delweddau ar wahân yn sicrhau bod pob delwedd yn ffyddlon i'w data. Felly, mae'r dull yn cynhyrchu delweddau o ansawdd uchel heb ollyngiadau nodweddion (Ffigur 6). Mae delweddau in-vivo lle cyflymwyd y sgan gan 87.5% yn dangos y gellir caffael delweddau o ansawdd uchel ar 12.5% o hyd protocol safonol (Ffigur 7).
Ffigur 7: Proseswyd delweddau wedi'u pwysoli â dwysedd proton, wedi'u pwysoli â T1 a T2 gyda'i gilydd i ailadeiladu delweddau o ansawdd uchel. Roedd yr holl brotocolau delweddu wedi'u cyflymu 87.5% o'i gymharu â'u fersiynau safonol (ffactor cyflymu R = 8). Dangosodd y dull arfaethedig (SIMIT) y Cnewyllyn Lentiform (saethau pinc) a'r cortecs opercular blaen (saeth melyn) yn gliriach. Roedd SIMIT hefyd yn darlunio ffiniau mater llwyd yn y sulci yn gliriach yn y delweddau wedi'u pwysoli â T1.
Mae sgoriau niwroradiolegydd dall a threfn ar hap yn tynnu sylw at berfformiad uwch SIMIT o ran gwerth diagnostig (Ffigur 8).
Ffigur 8: Mae sgoriau niwroradiolegydd yn tynnu sylw at berfformiad ailadeiladu delwedd gwell SIMIT. Roedd y niwroradiolegydd wedi'i dallu i enwau dulliau a chyflwynwyd delweddau mewn trefn ar hap.
Cyllid
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Gwobr Darganfod Ymddiriedolaeth Wellcome (2025 – 2033) – ~ £4.9M Democrateiddio Ymchwil Niwroddelweddu gydag MRI Derek Jones, Marco Palombo, Johnes Obungoloch, Emre Kopanoglu, Daniel Alexander, Andrew Webb, Mara Cercignani, Mark Griswold Rôl: Co-I Statws: Gweithredol |
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Partneriaeth Hyfforddiant Doethurol EPSRC - Ysgoloriaeth PhD (2024 - 2028) - £ 85,301 Mae'r curiad yn mynd ymlaen Ian Driver, Kevin Murphy, Emre Kopanoglu Rôl: Co-I Ysgoloriaeth PhD; 2024 - 2028 Statws: Gweithredol |
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Prifysgol Caerdydd – Ysgoloriaeth PhD (2024 – 2028) - £ 85,301 Sganwyr Delweddu Cyseiniant Magnetig (MRI): Dylunio Sganwyr MRI Cost Isel Iawn i sicrhau bod delweddu meddygol ar gael mewn lleoliadau heb eu hariannu Emre Kopanoglu, Derek K. Jones, Mara Cercignani Rôl: PI Ysgoloriaeth PhD; 2024 - 2028 Statws: Gweithredol |
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Grant Ymchwil SPF (2023 – 2028) - £ 29,810,359 Cyfleuster cenedlaethol ar gyfer sganio MRI dynol maes uchel iawn (11.7T) PI: Richard Bowtell. Cyd-I: Karin Shmueli, Shajan Gunamony, Jurgen Schneider, James Wild, Andrew Peet, Laura Parkes, Christopher Rodgers, Paul Glover, Ian Hall, Emre Kopanoglu, Zoe Kourtzi, Dorothee Auer, Harish Poptani, Penny Gowland, Shaihan Malik, Andrew Blamire, Damian Tyler, Andrew Bagshaw, Neal Bangerter, Geoff Parker, Derek Jones, Susan Francis, Paul Armitage, Jozien Goense, Peter Jezzard, Adam Berrington, Mara Cercignani, Ozlem Ipek, Steven Williams, Karen Mullinger, Rimona Weil, James Rowe, Daniel Alexander, Steven Sourbron, Peter Thelwall, Stuart Clare, Claudia Wheeler-Kingshott, Andrew Peters, Itamar Ronen Rôl: Co-I Statws: Gweithredol |
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Menter Offer Canol Ystod BBSRC (2023) - £ 860,000 Uwchraddio ein barn ar Tyfu'n Hŷn: Mapio Newidiadau i'r Ymennydd ar draws y Rhychwant Oes gyda MR Aml-Sbectrol Maes Uchel Uchel Mara Cercignani, John Evans, Derek Jones, Emre Kopanoglu, Michael Germuska, Daniel Gallichan, Kevin Murphy, Robert Turner Rôl: Co-I Statws: Gweithredol |
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Partneriaeth Hyfforddiant Doethurol EPSRC - Ysgoloriaeth PhD (2021 – 2025) - £ 81,528 Dulliau newydd i feintioli priodweddau magnetig axonal ac uniondeb myelin gan ddefnyddio MRI Marco Palombo, Emre Kopanoglu, Robert Turner Rôl: Co-I Ysgoloriaeth PhD; 2023 - 2027 Statws: Gweithredol |
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Sefydliad Arloesi Niwrowyddoniaeth ac Iechyd Meddwl Prifysgol Caerdydd – Gwobr Ymchwil Arweinwyr y Dyfodol mewn Niwrowyddoniaeth (2023) - £ 1,410 Cymorth teithio cynhadledd Statws: Cyflawn |
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Gwobr Cyflymydd Cenedl Data Llywodraeth Cymru (2022) - £ 8,836 Gwella ansawdd delwedd a diogelwch delweddu cyseiniant magnetig maes uchel iawn gan ddefnyddio rhagfynegiad maes electromagnetig sy'n seiliedig ar ddysgu dwfn Emre Kopanoglu, Alix Jean Deeley Plumley, Kevin Murphy Rôl: PI Statws: Cyflawn |
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Partneriaeth Hyfforddiant Doethurol EPSRC - Ysgoloriaeth PhD (2021 - 2025) - £ 72,404 Defnyddio dysgu peiriant i sicrhau diogelwch cleifion na allant aros yn llonydd yn ystod delweddu cyseiniant magnetig Emre Kopanoglu, Kevin Murphy Rôl: PI Ysgoloriaeth PhD; 2021 – 2025 Statws: Gweithredol |
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Gwobr Hadau ar gyfer Hadau Ymddiriedolaeth Wellcome (2018) - £ 20,000 Delweddu cyseiniant magnetig o gleifion sy'n symud mewn maes uchel iawn: cynnig yn gwaethygu'r arteffactau homogenedd oherwydd effeithiau tonfedd Emre Kopanoglu Rôl: PI Statws: Cyflawn |
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Partneriaeth Hyfforddiant Doethurol EPSRC – Ysgoloriaeth PhD (2018 – 2022) - £ 71,101 Delweddu Cyseiniant Magnetig swyddogaethol goddefgar cleifion yn y Maes Ultra-uchel Emre Kopanoglu, Kevin Murphy, Richard G. Wise. Rôl: PI Ysgoloriaeth PhD; 2018 - 2022 Statws: Cyflawn |
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Partneriaeth Hyfforddiant Doethurol EPSRC – Ysgoloriaeth PhD (2018 – 2022) - £ 71,101 Delweddu Cyseiniant Magnetig Cleifion Symudol ar Faes Ultra-uchel: Dyluniad Pwls Trosglwyddo Cyfochrog Cywiro Cynnig Amser Real Emre Kopanoglu, Kevin Murphy Rôl: PI Ysgoloriaeth PhD; 2018 - 2022 Statws: Cyflawn |
Grŵp ymchwil
Addysgu
Cymwysterau
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Cymrawd |
Academi Addysg Uwch, DU |
2023 |
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Cymrawd Addysgu Gwyddonol |
Prifysgol Yale, New Haven, CT, UDA |
2014 |
Modiwlau a addysgir
PST 518 Delweddu Dynol In-vivo
PS 3214: Niwroddelweddu mewn Iechyd a Chlefydau
PS 1018: Dulliau Ymchwil mewn Seicoleg
PS 3003: Lleoliad Galwedigaethol
PST 510: Prosiect Ymchwil Niwroddelweddu
PST 512: Cyflwyniad i Ddulliau Niwroddelweddu
PST 513: Dylunio a Dadansoddi Ymchwil mewn Niwroddelweddu
PST 514: Cyflwyniad i Ystadegau a Rhaglennu Matlab
PST 515: Cynnig Ymchwil Niwroddelweddu
Rolau Eraill
Darlithydd Gwadd, Ysgol Peirianneg Prifysgol Caerdydd, 2022 – 2024
Cyswllt Iechyd a Lles CUBRIC, 2024 –
Dirprwy Arweinydd Amgylchiadau Lliniarol, Ysgol Seicoleg Prifysgol Caerdydd, 2022 –
Swyddog Anabledd, Ysgol Seicoleg Prifysgol Caerdydd, 2022 –
Aelod o'r Pwyllgor Moeseg, Ysgol Seicoleg Prifysgol Caerdydd, 2022 –
Dirprwy Arweinydd Rhaglen MSc a Chyd-arweinydd Dros Dro, Ysgol Seicoleg Prifysgol Caerdydd, 2021 – 2022
Bywgraffiad
Addysg
- 2012: PhD mewn Peirianneg Drydanol ac Electroneg . Prifysgol Bilkent, Ankara, Twrci. Technegau Nofel ynghylch Cyfradd Amsugno Penodol a Maes Golwg Lleihau mewn Delweddu Cyseiniant Magnetig
- 2006: BSc mewn Peirianneg Drydanol ac Electroneg . Prifysgol Bilkent, Ankara, Twrci.
Cyflogaeth
- 2017 – presennol: Darlithydd / Uwch Ddarlithydd mewn Seicoleg. Prifysgol Caerdydd, Caerdydd, y DU.
- 2015 – 2017: Uwch Wyddonydd Ymchwil. Canolfan Ymchwil Aselsan, Ankara, Twrci.
- 2012 – 2015: Cyswllt Ôl-ddoethurol. Radioleg a Delweddu Biofeddygol. Prifysgol Yale, New Haven, CT, UDA.
- 2006 – 2012: Cynorthwy-ydd Ymchwil ac Addysgu. Peirianneg drydanol ac electroneg. Prifysgol Bilkent, Ankara, Twrci.
- 2006 – 2006: Cynorthwyydd Addysgu Israddedig. Peirianneg drydanol ac electroneg. Prifysgol Bilkent, Ankara, Twrci.
Ymrwymiadau siarad cyhoeddus
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Darlithydd |
ISMRT, Fforwm Arbennig ISMRM-ISMRT, Cyfarfod Blynyddol yr ISMRM ac ISMRT ISMRM, Penwythnos Addysgol, Cyfarfod Blynyddol yr ISMRM ac ISMRT ESMRMB, Darlithoedd ar MR, MRI trylediad a Sbectrosgopeg |
2024
2024 2023 |
Pwyllgorau ac adolygu
Profiad y Pwyllgor
Cyfredol
| Pwyllgor Rhaglennu Cyfarfod Blynyddol ISMRM | Aelodau | 2025 – presennol |
| Pwyllgor Cynghori ar Gynaliadwyedd ISMRM | Aelodau | 2024 – presennol |
| ISMRM Pennod Twrcaidd | Aelod o'r Bwrdd | 2023 – presennol |
| Pwyllgor Diogelwch MRI ISMRM | Aelodau | 2020 – presennol |
| Cadeirydd | 2021 – 2025 | |
| Pwyllgor Datblygu'r We ISMRM | Aelodau | 2021 – 2025 |
Sefydliad
| ISMRM – Cyfres Dosbarth Meistr Rhyngwladol RadAid ar Ddiogelwch MRI ar gyfer Gwledydd Incwm Isel a Chanolig | Cadeirydd y Pwyllgor Trefnu | 2026 |
| Gweithdy Rhaglen Arweinwyr y Dyfodol ISMRT ar Ddiogelwch MRI mewn cydweithrediad â Phwyllgor Diogelwch ISMRM a Rad-Aid International | Aelod o'r Pwyllgor Trefnu | 2025 |
| Darlithoedd ESMRMB ar MR, MRI Trylediad a Sbectrosgopeg | Aelod o'r Pwyllgor Trefnu | 2023 |
| Cyfarfod Blynyddol ISMRM Pennod Prydain ac Iwerddon | Is-gadeirydd y Pwyllgor Trefnu | 2022 |
Meysydd goruchwyliaeth
Goruchwyliaeth gyfredol
Prosiectau'r gorffennol
Myfyrwyr PhD blaenorol
- Alix Plumley
- Luke Watkins
- Bleddyn Owen Woodward
- Katherine Anna Blanter
Contact Details
+44 29225 10256
Canolfan Ymchwil Delweddu'r Ymennydd Prifysgol Caerdydd, Llawr 1, Ystafell 1.016, Heol Maendy, Caerdydd, CF24 4HQ
Themâu ymchwil
Arbenigeddau
- Efelychiad, modelu a rhaglennu delweddu meddygol
- Delweddu Cyseiniant Magnetig
- Diogelwch cleifion
- Prosesu Signal a Delwedd
- Synhwyro Cywasgedig