Trosolwyg
Mae fy ymchwil yn canolbwyntio ar ddadansoddi delweddau o ddata delweddu cyseiniant magnetig (MRI), gyda ffocws ar MRI trylediad yr ymennydd. Mae gen i ddiddordeb mewn echdynnu gwybodaeth anatomegol a thopolegol o dynograffeg MRI trylediad y gellir ei gymhwyso ymhellach i ddadansoddi data MRI a dulliau niwroddelweddu eraill. Mae fy ymchwil yn CUBRIC wedi canolbwyntio'n bennaf ar ddod o hyd i ffyrdd newydd o ddefnyddio tractograffeg i gysoni'r dadansoddiad o ddata MRI hydredol a gafwyd mewn gwahanol safleoedd ar gyfer pob pwynt amser.
Cyhoeddiad
2024
- Ashley, S. A., Merritt, K., Solmi, F., Luque Laguna, P., Reichenberg, A. and David, A. S. 2024. A longitudinal study of head circumference trajectories in autism and autistic traits.. Journal of Autism and Developmental Disorders (10.1007/s10803-024-06578-x)
2023
- MacIver, C. et al. 2023. Macro- and micro-structural Insights into primary dystonia A UK Biobank study. Journal of Neurology (10.1007/s00415-023-12086-2)
2022
- Casella, C. et al. 2022. Mutation-related magnetization-transfer, not axon density, drives white matter differences in premanifest Huntington's disease: Evidence from in vivo ultra-strong gradient MRI. Human Brain Mapping 43(11), pp. 3439-3460. (10.1002/hbm.25859)
2021
- Casella, C. et al. 2021. Mutation-related apparent myelin, not axon density, drives white matter differences in premanifest Huntington's disease: evidence from in vivo ultra-strong gradient MRI. [Online]. bioRxiv. (10.1101/2021.11.29.469517) Available at: https://doi.org/10.1101/2021.11.29.469517
- Merritt, K., Luque Laguna, P., Irfan, A. and David, A. S. 2021. Longitudinal Structural MRI Findings in Individuals at Genetic and Clinical High Risk for Psychosis: A Systematic Review. Frontiers in Psychiatry 12, article number: 620401. (10.3389/fpsyt.2021.620401)
Articles
- Ashley, S. A., Merritt, K., Solmi, F., Luque Laguna, P., Reichenberg, A. and David, A. S. 2024. A longitudinal study of head circumference trajectories in autism and autistic traits.. Journal of Autism and Developmental Disorders (10.1007/s10803-024-06578-x)
- MacIver, C. et al. 2023. Macro- and micro-structural Insights into primary dystonia A UK Biobank study. Journal of Neurology (10.1007/s00415-023-12086-2)
- Casella, C. et al. 2022. Mutation-related magnetization-transfer, not axon density, drives white matter differences in premanifest Huntington's disease: Evidence from in vivo ultra-strong gradient MRI. Human Brain Mapping 43(11), pp. 3439-3460. (10.1002/hbm.25859)
- Merritt, K., Luque Laguna, P., Irfan, A. and David, A. S. 2021. Longitudinal Structural MRI Findings in Individuals at Genetic and Clinical High Risk for Psychosis: A Systematic Review. Frontiers in Psychiatry 12, article number: 620401. (10.3389/fpsyt.2021.620401)
Websites
- Casella, C. et al. 2021. Mutation-related apparent myelin, not axon density, drives white matter differences in premanifest Huntington's disease: evidence from in vivo ultra-strong gradient MRI. [Online]. bioRxiv. (10.1101/2021.11.29.469517) Available at: https://doi.org/10.1101/2021.11.29.469517
Ymchwil
Pynciau ymchwil a phapurau cysylltiedig
Dadansoddiad ystadegol o ddata MRI trylediad
Modelu mathemategol y gofod topolegol a gynrychiolir gan dynograffi'r ymennydd
Datblygu fframweithiau sy'n seiliedig ar dtractograffeg ar gyfer cynrychioli a dadansoddi data sy'n seiliedig ar fodel-
Prosiect a Chyllid
Mapio Llwybrau Niwroddatblygiadol ar gyfer Anhwylder Seiciatrig Oedolion: ALSPAC-MRI-II
MRC Cyfeirnod Grant MR/S003436/1.
Cydweithredwyr ymchwil
Bywgraffiad
Addysg ôl-raddedig
PhD Niwroddelweddu
Coleg y Brenin Llundain, U.K (2014-2019)
M.Sc. Niwroddelweddu
Coleg y Brenin, Llundain, UDA (2013-2014)
Addysg israddedig
Licenciatura en Matemáticas (B.Sc + M.Sc. Mathemateg)
Universidad de Granada, Sbaen (1993-1999)
Cyflogaeth
01/2020 – Yn bresennol: Cyswllt Ymchwil
Prifysgol Caerdydd, Ysgol Seicoleg, Canolfan Ymchwil Delweddu'r Ymennydd Prifysgol Caerdydd (Cardiff UK)
10/2018 – 12/2019: Cyswllt Ymchwil
King's College Llundain, Llundain (Llundain)
Contact Details
Canolfan Ymchwil Delweddu'r Ymennydd Prifysgol Caerdydd, Heol Maendy, Caerdydd, CF24 4HQ