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Dr Joanna Martin
Cymrawd Ymchwil, Is-adran Meddygaeth Seicolegol a Niwrowyddorau Clinigol
- MartinJM1@caerdydd.ac.uk
- +44 29206 88363
- Adeilad Hadyn Ellis, Heol Maendy, Caerdydd, CF24 4HQ
Trosolwyg
Rwy'n Gymrawd Ymchwil sy'n gysylltiedig â Chanolfan Wolfson ar gyfer Iechyd Meddwl Pobl Ifanc a'r Ganolfan Geneteg a Genomeg Niwroseiciatrig. Rwy'n cael fy ariannu gan Gymrodoriaeth Uwch Ymchwil Iechyd a Gofal Cymru/NIHR. Mae fy mhrosiect cymrodoriaeth yn dwyn y teitl: "Gwella gwybodaeth, ymwybyddiaeth, a diagnosis o anhwylder gorfywiogrwydd diffyg sylw (ADHD) mewn menywod ifanc".
Fy ffocws ymchwil yw deall pam mae menywod yn llai tebygol na dynion o gael diagnosis o ADHD, yn ogystal â gwella gwybodaeth a diagnosis amserol o ADHD mewn menywod. Mae gen i ddiddordeb hefyd yn effaith ffactorau risg genetig ar iechyd meddwl plant a phenoteipiau niwroddatblygiadol, yn ogystal â nodweddion poblogaeth cysylltiedig. Mae fy ymchwil yn pontio meysydd epidemioleg, seiciatreg, a genomeg.
Cyhoeddiad
2023
- Weavers, B. et al. 2023. Characterising depression trajectories in young people at high familial risk of depression. Journal of Affective Disorders 337, pp. 66-74. (10.1016/j.jad.2023.05.063)
- Jonsson, L., Martin, J., Lichtenstein, P., Magnusson, P. K. E., Lundström, S., Westberg, L. and Tammimies, K. 2023. Examining neurodevelopmental problems in 15q11.2 (BP1‐BP2) copy number variation carriers at ages 9/12 and 18 in a Swedish twin sample. Molecular Genetics and Genomic Medicine 11(8), article number: e2191. (10.1002/mgg3.2191)
- Wang, S. et al. 2023. Rare X-linked variants carry predominantly male risk in Autism, Tourette Syndrome, and ADHD. Nature Communications
- Gosling, C. J. et al. 2023. Association between relative age at school and persistence of attention-deficit hyperactivity disorder in prospective studies: an individual participant data meta-analysis. The Lancet Psychiatry
- Lewis, K., Martin, J., Gregory, A. M., Anney, R., Thapar, A. and Langley, K. 2023. Sleep disturbances in ADHD: Investigating the contribution of polygenic liability for ADHD and sleep-related phenotypes. European Child and Adolescent Psychiatry 32, pp. 1253-1261. (10.1007/s00787-021-01931-2)
- Dennison, C. et al. 2023. Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry. Journal of Child Psychology and Psychiatry (10.1111/jcpp.13862)
- Dennison, C. A. et al. 2023. Stratifying early‐onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry. Journal of Child Psychology and Psychiatry (10.1111/jcpp.13862)
- Taylor, M. J. et al. 2023. A twin study of genetic and environmental contributions to ADHD over time. Journal of Child Psychology and Psychiatry (10.1111/jcpp.13854)
- Taylor, M. J. et al. 2023. A twin study of genetic and environmental contributions to attention‐deficit/hyperactivity disorder over time. Journal of Child Psychology and Psychiatry (10.1111/jcpp.13854)
- Khramtsova, E. A., Wilson, M. A., Martin, J., Winham, S. J., He, K. Y., Davis, L. K. and Stranger, B. E. 2023. Quality control and analytic best practices for testing genetic models of sex differences in large populations. Cell 186(10), pp. 2044-2061. (10.1016/j.cell.2023.04.014)
- Lynham, A. J. et al. 2023. DRAGON-Data: A platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts. BJPsych Open 9(2), article number: e32. (10.1192/bjo.2022.636)
- Devaney, J. et al. 2023. An agenda for future research regarding the mental health of young people with care experience. Child & Family Social Work (10.1111/cfs.13015)
- Cortese, S. et al. 2023. Candidate diagnostic biomarkers for neurodevelopmental disorders in children and adolescents: a systematic review. World Psychiatry 22(1), pp. 129-149. (10.1002/wps.21037)
- Demontis, D. et al. 2023. Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains. Nature Genetics 55, pp. 198-208. (10.1038/s41588-022-01285-8)
- Rajagopal, V. M. et al. 2023. Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity. Scientific Reports 13(1), article number: 429. (10.1038/s41598-022-26845-0)
- Martin, J. et al. 2023. Investigating direct and indirect genetic effects in attention-deficit/hyperactivity disorder using parent-offspring trios. Biological Psychiatry 93(1), pp. 37-44. (10.1016/j.biopsych.2022.06.008)
2022
- Taylor, M., Ronald, A., Martin, J., Lundström, S., Hosang, G. and Lichtenstein, P. 2022. Examining the association between autistic traits in childhood and adolescent hypomania: a longitudinal twin study. Psychological Medicine 52(15), pp. 3606-3615. (10.1017/S0033291721000374)
- Vainieri, I. et al. 2022. Polygenic association between attention-deficit/hyperactivity disorder liability and cognitive impairments. Psychological Medicine 52(14), pp. 3150-3158. (10.1017/S0033291720005218)
- Mattheisen, M. et al. 2022. Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups. Nature Genetics 54, pp. 1470-1478. (10.1038/s41588-022-01171-3)
- Martini, M. et al. 2022. Sex differences in mental health problems and psychiatric hospitalization in autistic young adults. JAMA Psychiatry
- Langley, K., Martin, J. and Thapar, A. 2022. Genetics of attention-deficit hyperactivity disorder. In: Current Topics in Behavioral Neurosciences. Berlin, Heidelberg:, pp. 1-26., (10.1007/7854_2022_338)
- Garcia-Argibay, M. et al. 2022. The role of ADHD genetic risk in mid-to-late life somatic health conditions. Translational Psychiatry 12(1), article number: 152. (10.1038/s41398-022-01919-9)
- Martin, J. and Hadwin, J. 2022. The roles of sex and gender in child and adolescent mental health. JCPP Advances 2(1) (10.1002/jcv2.12059)
- Hosang, G. et al. 2022. Association of etiological factors for hypomanic symptoms, bipolar disorder, and other severe mental illnesses. JAMA Psychiatry 79(2), pp. 143-150. (10.1001/jamapsychiatry.2021.3654)
- Langley, K., Martin, J. and Thapar, A. 2022. Genetics of attention deficit hyperactivity disorder. Springer Nature.
2021
- Ghirardi, L. et al. 2021. Familial and genetic associations between autism spectrum disorder and other neurodevelopmental and psychiatric disorders. Journal of Child Psychology and Psychiatry 62(11), pp. 1274-1284. (10.1111/jcpp.13508)
- Brikell, I., Burton, C., Roth Mota, N. and Martin, J. 2021. Insights into attention-deficit/hyperactivity disorder from recent genetic studies. Psychological Medicine 51(13), pp. 2274-2286. (10.1017/S0033291721000982)
- Martin, J. et al. 2021. Sex differences in anxiety and depression in children with ADHD investigating genetic liability and comorbidity. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 186(7), pp. 412-422. (10.1002/ajmg.b.32842)
- Martin, J. et al. 2021. Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression. PLoS ONE 16(9), article number: e0248254. (10.1371/journal.pone.0248254)
- Ip, H. F. et al. 2021. Genetic association study of childhood aggression across raters, instruments, and age. Translational Psychiatry 11(1), article number: 413. (10.1038/s41398-021-01480-x)
- Martin, J. et al. 2021. Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits. Biological Psychiatry 89(12), pp. 1127-1137. (10.1016/j.biopsych.2020.12.024)
- Powell, V., Martin, J., Thapar, A., Rice, F. and Anney, R. 2021. Investigating regions of shared genetic variation in attention deficit/hyperactivity disorder and major depressive disorder: a GWAS meta-analysis. Scientific Reports 11, article number: 7353. (10.1038/s41598-021-86802-1)
- Demontis, D. et al. 2021. Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder. Nature Communications 12(1), article number: 576. (10.1038/s41467-020-20443-2)
2020
- Powell, V. et al. 2020. What explains the link between childhood ADHD and adolescent depression? Investigating the role of peer relationships and academic attainment. European Child and Adolescent Psychiatry 29, pp. 1581-1591. (10.1007/s00787-019-01463-w)
- Vuijk, P. J. et al. 2020. Translating discoveries in Attention-Deficit/Hyperactivity Disorder genomics to an outpatient child and adolescent psychiatric cohort. Journal of the American Academy of Child and Adolescent Psychiatry 59(8), pp. 964-977. (10.1016/j.jaac.2019.08.004)
- Riglin, L. et al. 2020. Using genetics to examine a general liability to childhood psychopathology. Behavior Genetics 50, pp. 213-220. (10.1007/s10519-019-09985-4)
- Martin, J. et al. 2020. Investigating sex-specific effects of familial risk for ADHD and other neurodevelopmental disorders in the Swedish population. Bjpsych Open 6(4), article number: e65. (10.1192/bjo.2020.47)
- Martin, J. et al. 2020. A brief report: de novo copy number variants in children with attention deficit hyperactivity disorder. Translational Psychiatry 10, article number: 135. (10.1038/s41398-020-0821-y)
2019
- Lee, P. H. et al. 2019. Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders. Cell 179(7), pp. 1469-1482.e11. (10.1016/j.cell.2019.11.020)
- Yao, S. et al. 2019. Associations between Attention-Deficit/Hyperactivity Disorder and various eating disorders: A Swedish nationwide population study using multiple genetically informative approaches. Biological Psychiatry 86(8), pp. 577-586. (10.1016/j.biopsych.2019.04.036)
- Mowlem, F. D., Rosenqvist, M. A., Martin, J., Lichtenstein, P., Asherson, P. and Larsson, H. 2019. Sex differences in predicting ADHD clinical diagnosis and pharmacological treatment. European Child and Adolescent Psychiatry 28(4), pp. 481-489. (10.1007/s00787-018-1211-3)
- Taylor, M. J., Martin, J., Lu, Y., Brikell, I., Lundstrom, S., Larsson, H. and Lichtenstein, P. 2019. Association of genetic risk factors for psychiatric disorders and traits of these disorders in a Swedish population twin sample. JAMA Psychiatry 76(3), pp. 280-289. (10.1001/jamapsychiatry.2018.3652)
- Grove, J. et al. 2019. Identification of common genetic risk variants for autism spectrum disorder. Nature Genetics 51, pp. 431-444. (10.1038/s41588-019-0344-8)
- Demontis, D. et al. 2019. Discovery of the first genome-wide significant risk loci for attention-deficit/hyperactivity disorder. Nature Genetics 51, pp. 63-75. (10.1038/s41588-018-0269-7)
- Verhoef, E. et al. 2019. Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language. Translational Psychiatry 9, article number: 35. (10.1038/s41398-018-0324-2)
2018
- Martin, J., Tammimes, K., Karlsson, R., Lu, Y., Larsson, H., Lichtenstein, P. and Magnusson, P. K. 2018. Copy number variation and neuropsychiatric problems in females and males in the general population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 180(6), pp. 341-350. (10.1002/ajmg.b.32685)
- Martin, J., Taylor, M. J. and Lichtenstein, P. 2018. Assessing the evidence for shared genetic risks across psychiatric disorders and traits. Psychological Medicine 48(11), pp. 1759-1774. (10.1017/S0033291717003440)
- Martin, J. et al. 2018. Sex-specific manifestation of genetic risk for attention deficit hyperactivity disorder in the general population. Journal of Child Psychology and Psychiatry 59(8), pp. 908-916. (10.1111/jcpp.12874)
- Guyatt, A. L. et al. 2018. Association of copy number variation across the genome with neuropsychiatric traits in the general population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 177(5), pp. 489-502. (10.1002/ajmg.b.32637)
- Brikell, I. et al. 2018. The contribution of common genetic risk variants for ADHD to a general factor of childhood psychopathology. Molecular Psychiatry (10.1038/s41380-018-0109-2)
- Martin, J. et al. 2018. A genetic investigation of sex bias in the prevalence of attention-deficit/hyperactivity disorder. Biological Psychiatry 83(12), pp. 1044-1053. (10.1016/j.biopsych.2017.11.026)
2017
- Riglin, L. et al. 2017. Investigating the genetic underpinnings of early-life irritability. Translational Psychiatry 7, article number: e1241. (10.1038/tp.2017.212)
- Stergiakouli, E. et al. 2017. Association between polygenic risk scores for attention-deficit hyperactivity disorder and educational and cognitive outcomes in the general population. International Journal of Epidemiology 46(2), pp. 421-428. (10.1093/ije/dyw216)
- Stergiakouli, E. et al. 2017. Shared genetic influences between dimensional ASD and ADHD symptoms during child and adolescent development. Molecular Autism 8, article number: 18. (10.1186/s13229-017-0131-2)
2016
- Thapar, A. et al. 2016. Psychiatric gene discoveries shape evidence on ADHD's biology. Molecular Psychiatry 21, pp. 1202-1207. (10.1038/mp.2015.163)
- Mooney, M. A. et al. 2016. Pathway analysis in attention deficit hyperactivity disorder: an ensemble approach. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 171(6), pp. 815-826. (10.1002/ajmg.b.32446)
- Martin, J. et al. 2016. Association of genetic risk for schizophrenia with nonparticipation over time in a population-based cohort study. American Journal of Epidemiology 183(12), pp. 1149-1158. (10.1093/aje/kww009)
- Robinson, E. B. et al. 2016. Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population. Nature Genetics 48(5), pp. 552-555. (10.1038/ng.3529)
- Isles, A. R. et al. 2016. Parental origin of interstitial duplications at 15q11.2-q13.3 in schizophrenia and neurodevelopmental disorders. PLoS Genetics 12(5), article number: e1005993. (10.1371/journal.pgen.1005993)
- Aas, M. et al. 2016. Summaries of plenary, symposia, and oral sessions at the XXII World Congress of Psychiatric Genetics, Copenhagen, Denmark, 12-16 October 2014 [Conference Material]. Psychiatric Genetics 26(1), pp. 1-47. (10.1097/YPG.0000000000000112)
2015
- Niarchou, M., Martin, J., Thapar, A., Owen, M. J. and van den Bree, M. B. 2015. The clinical presentation of attention deficit-hyperactivity disorder (ADHD) in children with 22q11.2 deletion syndrome. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 168(8), pp. 730-738. (10.1002/ajmg.b.32378)
- Martin, J., Hamshere, M. L., Stergiakouli, E., O'Donovan, M. C. and Thapar, A. 2015. Neurocognitive abilities in the general population and composite genetic risk scores for attention-deficit hyperactivity disorder. Journal of Child Psychology and Psychiatry 56(6), pp. 648-656. (10.1111/jcpp.12336)
- Stergiakouli, E. et al. 2015. Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) traits in children and clinical ADHD. Journal of the American Academy of Child and Adolescent Psychiatry 54(4), pp. 322-327. (10.1016/j.jaac.2015.01.010)
- Martin, J., O'Donovan, M. C., Thapar, A., Langley, K. and Williams, N. 2015. The relative contribution of common and rare genetic variants to ADHD. Translational Psychiatry 5, article number: e506. (10.1038/tp.2015.5)
2014
- Martin, J., Hamshere, M. L., Stergiakouli, E., O'Donovan, M. C. and Thapar, A. 2014. Genetic risk for Attention Deficit/Hyperactivity Disorder contributes to neurodevelopmental traits in the general population. Biological Psychiatry 76(8), pp. 664-671. (10.1016/j.biopsych.2014.02.013)
- Martin, J. et al. 2014. Biological overlap of attention-deficit/hyperactivity disorder and autism spectrum disorder: evidence from copy number variants. Journal of the American Academy of Child and Adolescent Psychiatry 53(7), pp. 761-770.e26. (10.1016/j.jaac.2014.03.004)
- Cooper, M., Martin, J., Langley, K., Hamshere, M. L. and Thapar, A. 2014. Autistic traits in children with ADHD index clinical and cognitive problems. European Child & Adolescent Psychiatry 23(1), pp. 23-24. (10.1007/s00787-013-0398-6)
- Martin, J., Hamshere, M. L., O'Donovan, M. C., Rutter, M. and Thapar, A. 2014. Factor structure of autistic traits in children with ADHD. Journal of Autism and Developmental Disorders 44(1), pp. 204-215. (10.1007/s10803-013-1865-0)
- Martin, J. 2014. Examining the clinical and genetic overlap of Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder traits. PhD Thesis, Cardiff University.
2013
- Ahuja, A., Martin, J., Langley, K. and Thapar, A. 2013. Intellectual disability in children with attention deficit hyperactivity disorder. The Journal of Pediatrics 163(3), pp. 890-895.e1. (10.1016/j.jpeds.2013.02.043)
- Hamshere, M. L. et al. 2013. Shared polygenic contribution between childhood attention-deficit hyperactivity disorder and adult schizophrenia. British Journal of Psychiatry 203(2), pp. 107-111. (10.1192/bjp.bp.112.117432)
- Hamshere, M. L. et al. 2013. High loading of polygenic risk for ADHD in children with comorbid aggression. American Journal of Psychiatry 170(8), pp. 909-916. (10.1176/appi.ajp.2013.12081129)
2011
- Langley, K. et al. 2011. Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants. British Journal of Psychiatry 199(5), pp. 398-403.
Adrannau llyfrau
- Langley, K., Martin, J. and Thapar, A. 2022. Genetics of attention-deficit hyperactivity disorder. In: Current Topics in Behavioral Neurosciences. Berlin, Heidelberg:, pp. 1-26., (10.1007/7854_2022_338)
Erthyglau
- Weavers, B. et al. 2023. Characterising depression trajectories in young people at high familial risk of depression. Journal of Affective Disorders 337, pp. 66-74. (10.1016/j.jad.2023.05.063)
- Jonsson, L., Martin, J., Lichtenstein, P., Magnusson, P. K. E., Lundström, S., Westberg, L. and Tammimies, K. 2023. Examining neurodevelopmental problems in 15q11.2 (BP1‐BP2) copy number variation carriers at ages 9/12 and 18 in a Swedish twin sample. Molecular Genetics and Genomic Medicine 11(8), article number: e2191. (10.1002/mgg3.2191)
- Wang, S. et al. 2023. Rare X-linked variants carry predominantly male risk in Autism, Tourette Syndrome, and ADHD. Nature Communications
- Gosling, C. J. et al. 2023. Association between relative age at school and persistence of attention-deficit hyperactivity disorder in prospective studies: an individual participant data meta-analysis. The Lancet Psychiatry
- Lewis, K., Martin, J., Gregory, A. M., Anney, R., Thapar, A. and Langley, K. 2023. Sleep disturbances in ADHD: Investigating the contribution of polygenic liability for ADHD and sleep-related phenotypes. European Child and Adolescent Psychiatry 32, pp. 1253-1261. (10.1007/s00787-021-01931-2)
- Dennison, C. et al. 2023. Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry. Journal of Child Psychology and Psychiatry (10.1111/jcpp.13862)
- Dennison, C. A. et al. 2023. Stratifying early‐onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry. Journal of Child Psychology and Psychiatry (10.1111/jcpp.13862)
- Taylor, M. J. et al. 2023. A twin study of genetic and environmental contributions to ADHD over time. Journal of Child Psychology and Psychiatry (10.1111/jcpp.13854)
- Taylor, M. J. et al. 2023. A twin study of genetic and environmental contributions to attention‐deficit/hyperactivity disorder over time. Journal of Child Psychology and Psychiatry (10.1111/jcpp.13854)
- Khramtsova, E. A., Wilson, M. A., Martin, J., Winham, S. J., He, K. Y., Davis, L. K. and Stranger, B. E. 2023. Quality control and analytic best practices for testing genetic models of sex differences in large populations. Cell 186(10), pp. 2044-2061. (10.1016/j.cell.2023.04.014)
- Lynham, A. J. et al. 2023. DRAGON-Data: A platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts. BJPsych Open 9(2), article number: e32. (10.1192/bjo.2022.636)
- Devaney, J. et al. 2023. An agenda for future research regarding the mental health of young people with care experience. Child & Family Social Work (10.1111/cfs.13015)
- Cortese, S. et al. 2023. Candidate diagnostic biomarkers for neurodevelopmental disorders in children and adolescents: a systematic review. World Psychiatry 22(1), pp. 129-149. (10.1002/wps.21037)
- Demontis, D. et al. 2023. Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains. Nature Genetics 55, pp. 198-208. (10.1038/s41588-022-01285-8)
- Rajagopal, V. M. et al. 2023. Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity. Scientific Reports 13(1), article number: 429. (10.1038/s41598-022-26845-0)
- Martin, J. et al. 2023. Investigating direct and indirect genetic effects in attention-deficit/hyperactivity disorder using parent-offspring trios. Biological Psychiatry 93(1), pp. 37-44. (10.1016/j.biopsych.2022.06.008)
- Taylor, M., Ronald, A., Martin, J., Lundström, S., Hosang, G. and Lichtenstein, P. 2022. Examining the association between autistic traits in childhood and adolescent hypomania: a longitudinal twin study. Psychological Medicine 52(15), pp. 3606-3615. (10.1017/S0033291721000374)
- Vainieri, I. et al. 2022. Polygenic association between attention-deficit/hyperactivity disorder liability and cognitive impairments. Psychological Medicine 52(14), pp. 3150-3158. (10.1017/S0033291720005218)
- Mattheisen, M. et al. 2022. Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups. Nature Genetics 54, pp. 1470-1478. (10.1038/s41588-022-01171-3)
- Martini, M. et al. 2022. Sex differences in mental health problems and psychiatric hospitalization in autistic young adults. JAMA Psychiatry
- Garcia-Argibay, M. et al. 2022. The role of ADHD genetic risk in mid-to-late life somatic health conditions. Translational Psychiatry 12(1), article number: 152. (10.1038/s41398-022-01919-9)
- Martin, J. and Hadwin, J. 2022. The roles of sex and gender in child and adolescent mental health. JCPP Advances 2(1) (10.1002/jcv2.12059)
- Hosang, G. et al. 2022. Association of etiological factors for hypomanic symptoms, bipolar disorder, and other severe mental illnesses. JAMA Psychiatry 79(2), pp. 143-150. (10.1001/jamapsychiatry.2021.3654)
- Ghirardi, L. et al. 2021. Familial and genetic associations between autism spectrum disorder and other neurodevelopmental and psychiatric disorders. Journal of Child Psychology and Psychiatry 62(11), pp. 1274-1284. (10.1111/jcpp.13508)
- Brikell, I., Burton, C., Roth Mota, N. and Martin, J. 2021. Insights into attention-deficit/hyperactivity disorder from recent genetic studies. Psychological Medicine 51(13), pp. 2274-2286. (10.1017/S0033291721000982)
- Martin, J. et al. 2021. Sex differences in anxiety and depression in children with ADHD investigating genetic liability and comorbidity. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 186(7), pp. 412-422. (10.1002/ajmg.b.32842)
- Martin, J. et al. 2021. Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression. PLoS ONE 16(9), article number: e0248254. (10.1371/journal.pone.0248254)
- Ip, H. F. et al. 2021. Genetic association study of childhood aggression across raters, instruments, and age. Translational Psychiatry 11(1), article number: 413. (10.1038/s41398-021-01480-x)
- Martin, J. et al. 2021. Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits. Biological Psychiatry 89(12), pp. 1127-1137. (10.1016/j.biopsych.2020.12.024)
- Powell, V., Martin, J., Thapar, A., Rice, F. and Anney, R. 2021. Investigating regions of shared genetic variation in attention deficit/hyperactivity disorder and major depressive disorder: a GWAS meta-analysis. Scientific Reports 11, article number: 7353. (10.1038/s41598-021-86802-1)
- Demontis, D. et al. 2021. Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder. Nature Communications 12(1), article number: 576. (10.1038/s41467-020-20443-2)
- Powell, V. et al. 2020. What explains the link between childhood ADHD and adolescent depression? Investigating the role of peer relationships and academic attainment. European Child and Adolescent Psychiatry 29, pp. 1581-1591. (10.1007/s00787-019-01463-w)
- Vuijk, P. J. et al. 2020. Translating discoveries in Attention-Deficit/Hyperactivity Disorder genomics to an outpatient child and adolescent psychiatric cohort. Journal of the American Academy of Child and Adolescent Psychiatry 59(8), pp. 964-977. (10.1016/j.jaac.2019.08.004)
- Riglin, L. et al. 2020. Using genetics to examine a general liability to childhood psychopathology. Behavior Genetics 50, pp. 213-220. (10.1007/s10519-019-09985-4)
- Martin, J. et al. 2020. Investigating sex-specific effects of familial risk for ADHD and other neurodevelopmental disorders in the Swedish population. Bjpsych Open 6(4), article number: e65. (10.1192/bjo.2020.47)
- Martin, J. et al. 2020. A brief report: de novo copy number variants in children with attention deficit hyperactivity disorder. Translational Psychiatry 10, article number: 135. (10.1038/s41398-020-0821-y)
- Lee, P. H. et al. 2019. Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders. Cell 179(7), pp. 1469-1482.e11. (10.1016/j.cell.2019.11.020)
- Yao, S. et al. 2019. Associations between Attention-Deficit/Hyperactivity Disorder and various eating disorders: A Swedish nationwide population study using multiple genetically informative approaches. Biological Psychiatry 86(8), pp. 577-586. (10.1016/j.biopsych.2019.04.036)
- Mowlem, F. D., Rosenqvist, M. A., Martin, J., Lichtenstein, P., Asherson, P. and Larsson, H. 2019. Sex differences in predicting ADHD clinical diagnosis and pharmacological treatment. European Child and Adolescent Psychiatry 28(4), pp. 481-489. (10.1007/s00787-018-1211-3)
- Taylor, M. J., Martin, J., Lu, Y., Brikell, I., Lundstrom, S., Larsson, H. and Lichtenstein, P. 2019. Association of genetic risk factors for psychiatric disorders and traits of these disorders in a Swedish population twin sample. JAMA Psychiatry 76(3), pp. 280-289. (10.1001/jamapsychiatry.2018.3652)
- Grove, J. et al. 2019. Identification of common genetic risk variants for autism spectrum disorder. Nature Genetics 51, pp. 431-444. (10.1038/s41588-019-0344-8)
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- Martin, J. et al. 2018. Sex-specific manifestation of genetic risk for attention deficit hyperactivity disorder in the general population. Journal of Child Psychology and Psychiatry 59(8), pp. 908-916. (10.1111/jcpp.12874)
- Guyatt, A. L. et al. 2018. Association of copy number variation across the genome with neuropsychiatric traits in the general population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 177(5), pp. 489-502. (10.1002/ajmg.b.32637)
- Brikell, I. et al. 2018. The contribution of common genetic risk variants for ADHD to a general factor of childhood psychopathology. Molecular Psychiatry (10.1038/s41380-018-0109-2)
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- Riglin, L. et al. 2017. Investigating the genetic underpinnings of early-life irritability. Translational Psychiatry 7, article number: e1241. (10.1038/tp.2017.212)
- Stergiakouli, E. et al. 2017. Association between polygenic risk scores for attention-deficit hyperactivity disorder and educational and cognitive outcomes in the general population. International Journal of Epidemiology 46(2), pp. 421-428. (10.1093/ije/dyw216)
- Stergiakouli, E. et al. 2017. Shared genetic influences between dimensional ASD and ADHD symptoms during child and adolescent development. Molecular Autism 8, article number: 18. (10.1186/s13229-017-0131-2)
- Thapar, A. et al. 2016. Psychiatric gene discoveries shape evidence on ADHD's biology. Molecular Psychiatry 21, pp. 1202-1207. (10.1038/mp.2015.163)
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- Aas, M. et al. 2016. Summaries of plenary, symposia, and oral sessions at the XXII World Congress of Psychiatric Genetics, Copenhagen, Denmark, 12-16 October 2014 [Conference Material]. Psychiatric Genetics 26(1), pp. 1-47. (10.1097/YPG.0000000000000112)
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- Hamshere, M. L. et al. 2013. High loading of polygenic risk for ADHD in children with comorbid aggression. American Journal of Psychiatry 170(8), pp. 909-916. (10.1176/appi.ajp.2013.12081129)
- Langley, K. et al. 2011. Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants. British Journal of Psychiatry 199(5), pp. 398-403.
Gosodiad
- Martin, J. 2014. Examining the clinical and genetic overlap of Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder traits. PhD Thesis, Cardiff University.
Llyfrau
- Langley, K., Martin, J. and Thapar, A. 2022. Genetics of attention deficit hyperactivity disorder. Springer Nature.
Bywgraffiad
Rwyf wedi derbyn cyllid ar gyfer fy ymchwil drwy Gymrodoriaeth Uwch Ymchwil Iechyd a Gofal Cymru/NIHR, Grant Ymchwilydd Ifanc NARSAD gan Sefydliad Ymchwil Ymennydd ac Ymddygiad, gwobr COFUND Sêr Cymru gan Lywodraeth Cymru/UE, a Chymrodoriaeth Ôl-ddoethurol Syr Henry Wellcome.
Fel rhan o gymrodoriaeth Ymddiriedolaeth Wellcome, roeddwn yn gweithio yng Nghanolfan Ymchwil Seiciatrig Stanley (Caergrawnt, UDA) a'r Adran Epidemioleg a Bioystadegau Meddygol, Karolinska Institutet (Stockholm, Sweden), yn ogystal â Chanolfan MRC ar gyfer Geneteg a Genomeg Niwroseiciatrig ym Mhrifysgol Caerdydd.
Cwblheais fy PhD yn yr adran Seiciatreg Plant a'r Glasoed yng Nghanolfan MRC ar gyfer Geneteg a Genomeg Niwroseiciatrig yn 2014. Teitl fy nhraethawd ymchwil oedd "Archwilio Gorgyffwrdd Clinigol a Genetig Anhwylder Gorfywiogrwydd Diffyg Sylw a Nodweddion Anhwylder Sbectrwm Awtistiaeth" a gellir ei lawrlwytho'n rhydd.
Cyn fy PhD, cefais BSc mewn Seicoleg Arbrofol o Brifysgol Bryste ac yna gweithiais fel Cynorthwy-ydd Ymchwil ym Mhrifysgol Caerdydd, gan gasglu data a pherfformio dadansoddiadau fel rhan o Astudiaeth ADHD, Genes a'r Amgylchedd.
Anrhydeddau a dyfarniadau
Cymrodoriaethau a Grantiau
- Ymchwil Iechyd a Gofal Cymru/Cymrodoriaeth Uwch NIHR (2022)
- Grant Ymchwilydd Ifanc NARSAD gan Sefydliad Ymchwil Ymennydd ac Ymddygiad (2021)
- Gwobr Cymrodorion (MQ). Cyd-ymchwilydd (2021)
- MRC Glasoed, Iechyd Meddwl a'r Wobr Datblygu Meddwl: Ymgysylltu (MRC). Cyd-ymchwilydd (2020)
- Cymrodoriaeth MCSA COFUND Sêr Cymru wedi'i hariannu gan Horizon 2020 yr UE a Llywodraeth Cymru (2019)
- Cymrodoriaeth Ôl-ddoethurol Syr Henry Wellcome (2015)
Ysgoloriaethau a Gwobrau
- Gwobr Kramer-Pollnow am waith gwyddonol rhagorol ym maes ADHD (2021)
- Ysgoloriaeth Teithio Iau Sagvolden Eunethydis (2016)
- Gwobr Teithio ar gyfer Eunethydis 3ydd Cynhadledd Ryngwladol ADHD (2014)
- Grant Teithio i'r Gynhadledd, Y Gymdeithas Geneteg (2014)
- Grant Cymorth i Ymchwilwyr Cynnar, Prifysgol Caerdydd (2013)
- Gwobr Teithio Eunethydis 2il Cynhadledd Ryngwladol ADHD (2012)
- Ysgoloriaeth Gwyliau Ymddiriedolaeth Wellcome (2006)
- Grant Sylfaen Sidney Perry (2005/2006)
Safleoedd academaidd blaenorol
- Cymrawd Ymchwil (03.2019 – cyfredol) Canolfan MRC ar gyfer Geneteg a Genomeg Niwroseiciatrig, Prifysgol Caerdydd
- Syr Henry Wellcome Cymrawd Ôl-ddoethurol (03.2018 – 02.2019) Canolfan MRC ar gyfer Geneteg a Genomeg Niwroseiciatrig, Prifysgol Caerdydd
- Syr Henry Wellcome Cymrawd Ôl-ddoethurol (03.2016 – 02.2018) Adran Epidemioleg a Bioystadegau Meddygol, Karolinska Institutet, Stockholm, Sweden
- Syr Henry Wellcome Cymrawd Ôl-ddoethurol (02.2015 – 02.2016) Uned Geneteg Dadansoddol a Chyfieithol, Ysbyty Cyffredinol Massachusetts, Boston & Stanley Canolfan Ymchwil Seiciatrig, Sefydliad Broad MIT a Harvard, Caergrawnt, UDA
- Cyswllt Ymchwil (01.2015 – 02.2015) Canolfan MRC ar gyfer Geneteg a Genomeg Niwroseiciatrig, Prifysgol Caerdydd
- Myfyriwr PhD (01.2012 – 12.2014 ) Canolfan MRC ar gyfer Geneteg a Genomeg Niwroseiciatrig, Prifysgol Caerdydd
- Seicolegydd Ymchwil Cynorthwyol (02.2010 – 12.2011) Adran Meddygaeth Seicolegol, Prifysgol Caerdydd
Pwyllgorau ac adolygu
- Golygydd Cyswllt, JCPP Advances
- Aelod o'r Pwyllgor Amrywiaeth a Chynhwysedd Cydraddoldeb, Is-adran Meddygaeth Seicolegol a Niwrowyddorau Clinigol, Prifysgol Caerdydd
- Consortiwm Genomeg Seiciatrig (PGC) Cynrychiolydd Pwyllgor Mynediad Data ar gyfer Gweithgor ADHD
- adolygydd cymheiriaid (amrywiol)
Meysydd goruchwyliaeth
Myfyrwyr presennol
Prif oruchwyliwr Isabella Barclay (2023 - presennol). Teitl traethawd ymchwil: Deall rhesymau posibl dros oedi o ran diagnosis ADHD mewn menywod. Cyd-oruchwylwyr: Dr Kate Langley, Yr Athro Anita Thapar, Dr Mark Taylor (Karolinska Institutet, Sweden).
Cyd-oruchwyliwr Bryony Weavers (2022 - presennol). Teitl traethawd ymchwil: Plant rhieni isel eu hysbryd: Adnabod targedau addawol ar gyfer ymyrraeth. Cyd-oruchwylwyr: Yr Athro Fran Rice, Dr Lucy Riglin, yr Athro Anita Thapar.
Cyd-oruchwyliwr Louise Horstmann (2021 - presennol). Teitl traethawd ymchwil: Deall goblygiadau defnyddio gwahanol ddiffiniadau o anhwylder diffyg canolbwyntio gorfywiogrwydd. Cyd-oruchwylwyr: Dr Kate Langley, Dr Evie Stergiakouli (Prifysgol Bryste).
Goruchwyliaeth gyfredol
Isabella Barclay
Myfyriwr ymchwil
