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Trosolwyg
Rwy'n Uwch-ddarlithydd ar y llwybr Addysgu ac Ysgoloriaeth yn yr Ysgol Optometreg a Gwyddorau Gweledigaeth. Mae fy nghyfrifoldebau addysgu yn cynnwys addysgu mewn nifer o flynyddoedd a modiwlau blaenllaw ym Mlwyddyn 2. Rwyf hefyd yn Arweinydd Academaidd Llais Myfyrwyr ac Arweinydd Blwyddyn 2.
Cyhoeddiad
2022
- Bartlett, R. L. et al. 2022. Quantifying biomarkers of axonal degeneration in early glaucoma to find the disc at risk. Scientific Reports 12(1), article number: 9366. (10.1038/s41598-022-12036-4)
2014
- Anantrasirichai, N. et al. 2014. Adaptive-weighted bilateral filtering and other pre-processing techniques for optical coherence tomography. Computerized Medical Imaging and Graphics 38(6), pp. 526-539. (10.1016/j.compmedimag.2014.06.012)
2013
- North, R. V. et al. 2013. Lamina cribrosa pore analysis in glaucomatous human optic nerve heads in vivo. Presented at: Association for Research in Vision and Ophthalmology, Seattle, WA, USA, 5-9 May 2013.
2012
- Mortlock, K. E. et al. 2012. Three dimensional (3D) segmentation of normal and glaucomatous optic nerve heads in 1050nm optical coherence tomography (OCT) datasets. Presented at: Association for Research in Vision and Ophthalmology, Fort Lauderdale, FL., USA, 6-9 May 2012.
2011
- Binns, A., Mortlock, K. E. and North, R. V. 2011. The relationship between stimulus intensity and response amplitude for the photopic negative response of the flash electroretinogram. Documenta Ophthalmologica 122(1), pp. 39-52. (10.1007/s10633-010-9257-7)
2010
- Mortlock, K. E., Binns, A., Aldebasi, Y. H. and North, R. V. 2010. Inter-subject, inter-ocular and inter-session repeatability of the photopic negative response of the electroretinogram recorded using DTL and skin electrodes. Documenta Ophthalmologica 121(2), pp. 123-134. (10.1007/s10633-010-9239-9)
- Mortlock, K. E. et al. 2010. 1050nm optical coherence tomography of the ageing and glaucomatous optic nerve head. Presented at: EUROMECH Colloquim, Imperial College, London, UK, 26-28 July, 2010.
- McDonnell, B. et al. 2010. The relationship between large artery stiffness, wave reflection and pulsatility in the micro-circulation: new insights into management of both hypertension and diabetes [Abstract]. Journal of Hypertension 28(E-SupA), pp. E166-E167. (10.1097/01.hjh.0000378713.53215.5d)
2008
- Drasdo, N., Mortlock, K. E. and North, R. V. 2008. Ganglion Cell Loss and Dysfunction: Relationship to Perimetric Sensitivity. Optometry and Vision Science 85(11), pp. 1036-1042. (10.1097/OPX.0b013e31818b94af)
2005
- Mortlock, K. E., Chiti, Z., Drasdo, N., Owens, D. R. and North, R. V. 2005. Silent substitution S-cone electroretinogram in subjects with diabetes mellitus. Ophthalmic and physiological optics 25(5), pp. 392-399. (10.1111/j.1475-1313.2005.00299.x)
2003
- Chiti, Z., North, R. V., Mortlock, K. E. and Drasdo, N. 2003. The S-cone electroretinogram: a comparison of techniques, normative data and age-related variation. Ophthalmic And Physiological Optics 23(4), pp. 370-376. (10.1046/j.1475-1313.2003.00129.x)
- Mortlock, K. E., Chiti, Z., North, R. V., Drasdo, N. and Owens, D. R. 2003. Dr L/M and S-Cone ERGs in subjects with no or early diabetic retinopathy. Presented at: Association for Research in Vision and Ophthalmology, Fort Lauderdale, FL., US, 4-8 May 2003.
2002
- Drasdo, N., Aldebasi, Y. H. F., Mortlock, K. E., Chiti, Z., Morgan, J. E., North, R. V. and Wild, J. M. 2002. Ocular optics, electroretinography and primary open angle glaucoma. Ophthalmic and Physiological Optics 22(5), pp. 455-462. (10.1046/j.1475-1313.2002.00078.x)
2001
- Drasdo, N., Aldebasi, Y. H. F., Chiti, Z., Mortlock, K. E., Morgan, J. E. and North, R. V. 2001. The S-cone PhNR and pattern ERG in primary open angle glaucoma. Investigative Ophthalmology and Visual Science 42(6), pp. 1266-1272.
- Mortlock, K. E. 2001. Electrophysiological examination of retinal function in Type I diabetes mellitus. PhD Thesis, Cardiff University.
Cynadleddau
- North, R. V. et al. 2013. Lamina cribrosa pore analysis in glaucomatous human optic nerve heads in vivo. Presented at: Association for Research in Vision and Ophthalmology, Seattle, WA, USA, 5-9 May 2013.
- Mortlock, K. E. et al. 2012. Three dimensional (3D) segmentation of normal and glaucomatous optic nerve heads in 1050nm optical coherence tomography (OCT) datasets. Presented at: Association for Research in Vision and Ophthalmology, Fort Lauderdale, FL., USA, 6-9 May 2012.
- Mortlock, K. E. et al. 2010. 1050nm optical coherence tomography of the ageing and glaucomatous optic nerve head. Presented at: EUROMECH Colloquim, Imperial College, London, UK, 26-28 July, 2010.
- Mortlock, K. E., Chiti, Z., North, R. V., Drasdo, N. and Owens, D. R. 2003. Dr L/M and S-Cone ERGs in subjects with no or early diabetic retinopathy. Presented at: Association for Research in Vision and Ophthalmology, Fort Lauderdale, FL., US, 4-8 May 2003.
Erthyglau
- Bartlett, R. L. et al. 2022. Quantifying biomarkers of axonal degeneration in early glaucoma to find the disc at risk. Scientific Reports 12(1), article number: 9366. (10.1038/s41598-022-12036-4)
- Anantrasirichai, N. et al. 2014. Adaptive-weighted bilateral filtering and other pre-processing techniques for optical coherence tomography. Computerized Medical Imaging and Graphics 38(6), pp. 526-539. (10.1016/j.compmedimag.2014.06.012)
- Binns, A., Mortlock, K. E. and North, R. V. 2011. The relationship between stimulus intensity and response amplitude for the photopic negative response of the flash electroretinogram. Documenta Ophthalmologica 122(1), pp. 39-52. (10.1007/s10633-010-9257-7)
- Mortlock, K. E., Binns, A., Aldebasi, Y. H. and North, R. V. 2010. Inter-subject, inter-ocular and inter-session repeatability of the photopic negative response of the electroretinogram recorded using DTL and skin electrodes. Documenta Ophthalmologica 121(2), pp. 123-134. (10.1007/s10633-010-9239-9)
- McDonnell, B. et al. 2010. The relationship between large artery stiffness, wave reflection and pulsatility in the micro-circulation: new insights into management of both hypertension and diabetes [Abstract]. Journal of Hypertension 28(E-SupA), pp. E166-E167. (10.1097/01.hjh.0000378713.53215.5d)
- Drasdo, N., Mortlock, K. E. and North, R. V. 2008. Ganglion Cell Loss and Dysfunction: Relationship to Perimetric Sensitivity. Optometry and Vision Science 85(11), pp. 1036-1042. (10.1097/OPX.0b013e31818b94af)
- Mortlock, K. E., Chiti, Z., Drasdo, N., Owens, D. R. and North, R. V. 2005. Silent substitution S-cone electroretinogram in subjects with diabetes mellitus. Ophthalmic and physiological optics 25(5), pp. 392-399. (10.1111/j.1475-1313.2005.00299.x)
- Chiti, Z., North, R. V., Mortlock, K. E. and Drasdo, N. 2003. The S-cone electroretinogram: a comparison of techniques, normative data and age-related variation. Ophthalmic And Physiological Optics 23(4), pp. 370-376. (10.1046/j.1475-1313.2003.00129.x)
- Drasdo, N., Aldebasi, Y. H. F., Mortlock, K. E., Chiti, Z., Morgan, J. E., North, R. V. and Wild, J. M. 2002. Ocular optics, electroretinography and primary open angle glaucoma. Ophthalmic and Physiological Optics 22(5), pp. 455-462. (10.1046/j.1475-1313.2002.00078.x)
- Drasdo, N., Aldebasi, Y. H. F., Chiti, Z., Mortlock, K. E., Morgan, J. E. and North, R. V. 2001. The S-cone PhNR and pattern ERG in primary open angle glaucoma. Investigative Ophthalmology and Visual Science 42(6), pp. 1266-1272.
Gosodiad
- Mortlock, K. E. 2001. Electrophysiological examination of retinal function in Type I diabetes mellitus. PhD Thesis, Cardiff University.
Ymchwil
Research Topics and Related Projects:
Recent research has investigated structural changes within the optic nerve head (ONH), more specifically the lamina cribrosa and inner retina in open angle glaucoma using novel laboratory 1050nm optical coherence tomography (OCT). OCT is an imaging technique which can provide high resolution, three dimensional images of ocular structures in vivo. The use of longer wavelength light sources, such as 1050nm, increases tissue penetration and this enables the examination of deeper ocular structures such as the lamina cribrosa and choroid, which until recently have been virtually impossible to image in vivo. The lamina cribrosa is a key structure in the pathogenesis of glaucoma, as it is thought to be the initial site of ganglion cell axonal damage. Using 1050nm OCT, we have been able to examine and identify changes in the lamina cribrosa in subjects with early and advanced glaucoma.
Figure 1. 20 ° x 20 ° 3D rendered view of ONH of healthy control subject, showing surrounding retinal layers, choroid and inner sclera. Deeper structures within the ONH are revealed, showing the prelaminar and laminar regions. The extracted rendered section shows detail within the lamina cribrosa, including pore pathways and laminar beams.
The images shown below are en face OCT images of the right eye of two subjects, a healthy control subject (left) and a subject with advanced glaucoma (right), at the level of the anterior lamina cribrosa. Structural changes are clearly evident in the advanced glaucoma subject, with significant pore enlargement in the central and superior regions and marked deformation of the inferior lamina cribrosa.
The three dimensional capabilities of the OCT system have also permitted visualisation of the pores of the lamina cribrosa, presenting further opportunities to understand how this structure is altered during the development of glaucoma. The image below represents a 500 x 500 x 300 µm section of lamina cribrosa in a subject with early glaucoma, showing connections between pores as bundles of nerve fibres travel through the optic nerve head.
Analysis of the ganglion cell complex $acirc; the three innermost layers of the retina $acirc; using OCT scans, has allowed assessment of retinal ganglion cell and nerve fibre layer loss in glaucoma. The image below shows segmentation of the three individual inner retinal layers, with resulting retinal thickness maps in a control and glaucoma subject from these layers shown below.
This research has been undertaken as part of the work of the Optic Nerve Head Group led by Dr Julie Albon, with Prof Rachel North and Prof James Morgan and imaging support from Nick White and Dr James Fergusson from VSBL
Addysgu
Roeddwn yn rhan o'r tîm a gyflogwyd i ddatblygu'r Flwyddyn Ragarweiniol fewnol yn yr Ysgol Optometreg a Gwyddorau Gweledigaeth yn 2013. Rwyf wedi dysgu amrywiaeth o bynciau clinigol, gwyddoniaeth sylfaenol a sgiliau astudio trwy gydol y cwrs gradd israddedig. Ar hyn o bryd rwy'n arwain dau fodiwl ail flwyddyn ac rwyf wedi arwain modiwlau yn y blynyddoedd Rhagarweiniol a'r blynyddoedd cyntaf yn flaenorol. Rwy'n goruchwylio prosiectau yn rheolaidd ar lefel UG a PGT.
Roeddwn yn Arweinydd Blwyddyn ar y cyd ac yn Gydlynydd Cwrs ar gyfer y Flwyddyn Ragarweiniol rhwng 2013 a 2017 a deuthum yn Arweinydd Blwyddyn 2 yn 2022.
Rwy'n ymgymryd â nifer o rolau eraill sy'n gysylltiedig ag addysgu, gan gynnwys Tiwtor Personol, Gweinyddwr Parth Dysgu Canolog, Arweinydd Academaidd Llais Myfyrwyr ac aelodaeth o'r tîm Rheoli Addysgu UG.
Rwyf wedi bod yn Gymrawd yr Academi Addysg Uwch ers mis Rhagfyr 2016.
Bywgraffiad
Educational and Professional Qualifications:
1996 $acirc; 2001: PhD, Neurophysiological investigation of retinal function in Type I diabetes mellitus, Cardiff University
1996: Membership, College of Optometrists
1992 $acirc; 1995: BSc (Hons), Optometry and Vision Sciences, Cardiff University
Academic Positions:
2013 onwards: Teaching Fellow, School of Optometry and Vision Sciences, Cardiff University
2002 $acirc; 2013: Research Associate (part-time since 2004), School of Optometry and Vision Sciences, Cardiff University
1996 $acirc; 1999: Clinical Demonstrator, School of Optometry and Vision Sciences, Cardiff University
School Roles and Committees:
2013: Learning Central Domain Administrator
Innovation and Engagement:
Contributed text to an exhibit about the visual system in $acirc; All About Me$acirc; in @Bristol, an exhibition funded by the Wellcome Trust.
Aelodaethau proffesiynol
- Cofrestrwyd gyda'r Cyngor Optegol Cyffredinol
- Aelod o'r Coleg Optometryddion
Safleoedd academaidd blaenorol
| 2024 ymlaen | Uwch Ddarlithydd (rhan-amser), Ysgol Optometreg a Gwyddorau Golwg, Prifysgol Caerdydd |
| 2015 - 2024 | Darlithydd (rhan-amser), Ysgol Optometreg a Gwyddorau Golwg, Prifysgol Caerdydd |
| 2013 - 2014 | Cymrawd Addysgu (rhan-amser), Ysgol Optometreg a Gwyddorau Golwg, Prifysgol Caerdydd |
| 2002 - 2013 | Cydymaith Ymchwil (rhan-amser ers 2004), Ysgol Optometreg a Gwyddorau Golwg, Prifysgol Caerdydd |
| 1996 - 1999 | Arddangoswr Clinigol, Ysgol Optometreg a Gwyddorau Golwg, Prifysgol Caerdydd |
Pwyllgorau ac adolygu
- 2013- Learning Central Domain Administrator
Contact Details
Optometreg a Gwyddorau'r Golwg , Ystafell 2.19, Heol Maendy, Cathays, Caerdydd, CF24 4HQ