Dr Eleri Owen-Jones
(hi/ei)
BSc (Hons), PhD
Research Associate
- Siarad Cymraeg
- Ar gael fel goruchwyliwr ôl-raddedig
Trosolwyg
Rwy'n rheolwr treial/cydymaith ymchwil yn y Ganolfan Treialon Ymchwil. Mae gen i brofiad clinigol mewn amrywiaeth eang o ddisgyblaethau. Ar hyn o bryd rwy'n rheoli'r astudiaeth Sono-breech - gwerthuso defnyddio dyfeisiau uwchsain â llaw i ganfod beichiogrwydd breech; y treial Solutions - gwerthuso therapi sy'n canolbwyntio ar ddatrysiad i blant a phobl ifanc sy'n cyflwyno mewn ystafell ddalfa'r heddlu; Stand Together - gwerthuso rhaglen gwrth-fwlio o'r enw KiVa mewn ysgolion; Treial TAPERS - Trin Gorbryder i Reslapse PrevEnt mewn pSychosis: treial dichonoldeb, a ariennir gan Research for Patient and Public Benefit (RfPPB) Wales; a'r astudiaeth TTTS - uwchsain sy'n canolbwyntio dwysedd uchel dan arweiniad uwchsain ar gyfer trin beichiogrwydd cynnar Syndrom Trallwyso Twin-Twin a ariennir gan yr MRC.
Ymhlith y treialon blaenorol yr wyf wedi'u rheoli mae'r canlynol: treial PRINCESS - Probiotics to Reduce Infections iN CarE home reSidentS a ariennir gan NIHR EME; Blociau Adeiladu - Gwerthuso'r rhaglen Partneriaeth Nyrsys Teulu yn Englnd; CREAM - Plant gydag ecsema, stuttering; Astudiaeth ar hap, dwbl-ddall, a reolir gan placebo, o RAD001 (Everolimus) wrth drin problemau niwrowybyddol mewn sglerosis tiwbaidd.
Cyhoeddiad
2024
- Bowes, L. et al. 2024. The effects and costs of an anti-bullying programme (KiVa) in UK primary schools: a multicentre cluster randomised controlled trial. Psychological Medicine (10.1017/S0033291724002666)
- Thompson, P. A. et al. 2024. Statistical analysis plan for the SOLUTIONS randomised controlled trial with internal pilot: Solution Focused Brief Therapy (SFBT) in 10–17-year-olds presenting at policy custody. Trials 25, article number: 633. (10.1186/s13063-024-08457-3)
2023
- Gillespie, D. et al. 2023. Gut microbiology of UK care home residents: cross-sectional analysis from a randomised controlled trial. Clinical Microbiology and Infection 29(11), pp. 1437-1442. (10.1016/j.cmi.2023.08.001)
2022
- Robling, M. et al. 2022. A nurse-led home-visitation programme for first-time mothers in reducing maltreatment and improving child health and development (BB:2-6): longer-term outcomes from a randomised cohort using data-linkage. BMJ Open 12(2), article number: e049960. (10.1136/bmjopen-2021-049960)
2021
- Castro-Herrera, V. M. et al. 2021. Combination of the probiotics Lacticaseibacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis, BB-12 has limited effect on biomarkers of immunity and inflammation in older people resident in care homes: results from the Probiotics to Reduce Infections iN CarE home reSidentS Randomized, Controlled Trial. Frontiers in Immunology 12, article number: 643321. (10.3389/fimmu.2021.643321)
- M.Castro-Herrera, V. et al. 2021. Relationship between age, frailty, length of care home residence and biomarkers of immunity and inflammation in older care residents in the UK. Frontiers in Aging 2, article number: 599084. (10.3389/fragi.2021.599084)
2020
- Butler, C. C. et al. 2020. Effect of probiotic use on antibiotic administration among care home residents: a randomized clinical trial. Journal of the American Medical Association 324(1), pp. 47 - 56. (10.1001/jama.2020.8556)
2019
- Owen-Jones, E. et al. 2019. Protocol for a double-blind placebo-controlled trial to evaluate the efficacy of probiotics in reducing antibiotics for infection in care home residents: the Probiotics to Reduce Infections iN CarE home reSidentS (PRINCESS) trial. BMJ Open 9(6), article number: e027513. (10.1136/bmjopen-2018-027513)
2017
- Lugg-Widger, F. et al. 2017. Assessing the medium-term impact of a home-visiting programme on child maltreatment in England: protocol for a routine data linkage study. BMJ Open 7, article number: e015728. (10.1136/bmjopen-2016-015728)
2016
- Randell, E. et al. 2016. The use of everolimus in the treatment of neurocognitive problems in tuberous sclerosis (TRON): study protocol for a randomised controlled trial. Trials 17, article number: 398. (10.1186/s13063-016-1446-6)
- Robling, M. et al. 2016. Effectiveness of a nurse-led intensive home-visitation programme for first-time teenage mothers (Building Blocks): a pragmatic randomised controlled trial. Lancet 387(10014), pp. 146-155. (10.1016/S0140-6736(15)00392-X)
2013
- Owen-Jones, C. E. et al. 2013. The effectiveness and cost-effectiveness of the Family Nurse Partnership home visiting programme for first time teenage mothers in England: a protocol for the Building Blocks randomised controlled trial. BMC Pediatrics 13(114) (10.1186/1471-2431-13-114)
2010
- Kinnersley, P. R. et al. 2010. The need to improve the interface between in-hours and out-of-hours GP care, and between out-of-hours care and self-care. Family Practice 27(6), pp. 664-672. (10.1093/fampra/cmq056)
- Kelly, M. J. et al. 2010. Delays in response and triage times reduce patient satisfaction and enablement after using out-of-hours services. Family Practice 27(6), pp. 652-663. (10.1093/fampra/cmq057)
2004
- Owen-Jones, C. E. 2004. Stem cells in human oral epithelium. PhD Thesis, Cardiff University.
2002
- Baines, P. et al. 2002. Increased circulating normal and BCR-ABL+Ve progenitor numbers in Philadelphia chromosome-positive acute myeloid leukaemia. Leukemia Research 26(11), pp. 997-1005. (10.1016/S0145-2126(02)00049-8)
1999
- Robinson, L. G., Owen-Jones, C. E., Austin, S., Mills, K. I. and Burnett, A. K. 1999. Relationship between PCR status following chemotherapy and outcome in t(8;21) positive acute myeloid leukaemia [Abstract]. British Journal of Haematology 105(Sup.1), pp. 67.
- Austin, S. J., Robinson, L. G., Owen-Jones, C. E., Mills, K. I. and Burnett, A. 1999. Quantitation of AML1-ETO fusion transcripts in t(8;21) positive AML using real-time light cycler PCR [Abstract]. British Journal of Haematology 105, pp. 76.
- Robinson, L. G. et al. 1999. Altered gene expression in 32D cells expressing the AML1A gene or AML1-ETO fusion gene. British Journal of Haematology 105(Supp1), pp. 103-103.
- Owen-Jones, C., Robinson, L. G., Austin, S., Bailey-Wood, R., Agar, A., Mills, K. and Burnett, A. K. 1999. Absence of leukaemic cell contamination of bone marrow (BM) and peripheral blood stem cell (PBSC) harvests as detected by PCR in good risk Acute Myeloid Leukaemia. British Journal of Haematology 105(Supp 1), pp. 56-56.
1998
- Austin, S. J., Robinson, L. G., Owen-Jones, C. E., Mills, K. I. and Burnett, A. K. 1998. Real-time PCR (lightcycler technology) for quantitation of AML1-ETO fusion transcripts in t(8;21) positive AML. Blood 92(10), pp. 75A-75A.
- Robinson, L. G., Austin, S. J., Owen-Jones, C. E., Al-Sabah, A., Bailey-Wood, R., Mills, K. I. and Burnett, A. K. 1998. Prognostic value of IgH rearrangement detection in peripheral blood stem cell (PBSC) harvests of patients with Multiple Myeloma undergoing PBSC transplantation [Abstract]. British Journal of Haematology 102(1), pp. 292-293. (10.1111/j.1365-2141.1998.tb08997.x)
- Robinson, L. G., Austin, S. J., Owen-Jones, C. E., Langabeer, S. E., Linch, D. C., Mills, K. I. and Burnett, A. 1998. Multiplex PCR for the detection of prognostically important gene rearrangements in acute myeloid leukaemia [Abstract]. British Journal of Haematology 101(S), pp. 21.
1997
- Robinson, L., Owen-Jones, C. E., Bowen, D., Langabeer, S., Linch, D., Mills, K. I. and Burnett, A. K. 1997. Multiplex PCR for the detection of prognostically important chromosomal abnormalities in acute myeloid leukaemia [Abstract]. Blood 90(10), pp. 276.
Erthyglau
- Bowes, L. et al. 2024. The effects and costs of an anti-bullying programme (KiVa) in UK primary schools: a multicentre cluster randomised controlled trial. Psychological Medicine (10.1017/S0033291724002666)
- Thompson, P. A. et al. 2024. Statistical analysis plan for the SOLUTIONS randomised controlled trial with internal pilot: Solution Focused Brief Therapy (SFBT) in 10–17-year-olds presenting at policy custody. Trials 25, article number: 633. (10.1186/s13063-024-08457-3)
- Gillespie, D. et al. 2023. Gut microbiology of UK care home residents: cross-sectional analysis from a randomised controlled trial. Clinical Microbiology and Infection 29(11), pp. 1437-1442. (10.1016/j.cmi.2023.08.001)
- Robling, M. et al. 2022. A nurse-led home-visitation programme for first-time mothers in reducing maltreatment and improving child health and development (BB:2-6): longer-term outcomes from a randomised cohort using data-linkage. BMJ Open 12(2), article number: e049960. (10.1136/bmjopen-2021-049960)
- Castro-Herrera, V. M. et al. 2021. Combination of the probiotics Lacticaseibacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis, BB-12 has limited effect on biomarkers of immunity and inflammation in older people resident in care homes: results from the Probiotics to Reduce Infections iN CarE home reSidentS Randomized, Controlled Trial. Frontiers in Immunology 12, article number: 643321. (10.3389/fimmu.2021.643321)
- M.Castro-Herrera, V. et al. 2021. Relationship between age, frailty, length of care home residence and biomarkers of immunity and inflammation in older care residents in the UK. Frontiers in Aging 2, article number: 599084. (10.3389/fragi.2021.599084)
- Butler, C. C. et al. 2020. Effect of probiotic use on antibiotic administration among care home residents: a randomized clinical trial. Journal of the American Medical Association 324(1), pp. 47 - 56. (10.1001/jama.2020.8556)
- Owen-Jones, E. et al. 2019. Protocol for a double-blind placebo-controlled trial to evaluate the efficacy of probiotics in reducing antibiotics for infection in care home residents: the Probiotics to Reduce Infections iN CarE home reSidentS (PRINCESS) trial. BMJ Open 9(6), article number: e027513. (10.1136/bmjopen-2018-027513)
- Lugg-Widger, F. et al. 2017. Assessing the medium-term impact of a home-visiting programme on child maltreatment in England: protocol for a routine data linkage study. BMJ Open 7, article number: e015728. (10.1136/bmjopen-2016-015728)
- Randell, E. et al. 2016. The use of everolimus in the treatment of neurocognitive problems in tuberous sclerosis (TRON): study protocol for a randomised controlled trial. Trials 17, article number: 398. (10.1186/s13063-016-1446-6)
- Robling, M. et al. 2016. Effectiveness of a nurse-led intensive home-visitation programme for first-time teenage mothers (Building Blocks): a pragmatic randomised controlled trial. Lancet 387(10014), pp. 146-155. (10.1016/S0140-6736(15)00392-X)
- Owen-Jones, C. E. et al. 2013. The effectiveness and cost-effectiveness of the Family Nurse Partnership home visiting programme for first time teenage mothers in England: a protocol for the Building Blocks randomised controlled trial. BMC Pediatrics 13(114) (10.1186/1471-2431-13-114)
- Kinnersley, P. R. et al. 2010. The need to improve the interface between in-hours and out-of-hours GP care, and between out-of-hours care and self-care. Family Practice 27(6), pp. 664-672. (10.1093/fampra/cmq056)
- Kelly, M. J. et al. 2010. Delays in response and triage times reduce patient satisfaction and enablement after using out-of-hours services. Family Practice 27(6), pp. 652-663. (10.1093/fampra/cmq057)
- Baines, P. et al. 2002. Increased circulating normal and BCR-ABL+Ve progenitor numbers in Philadelphia chromosome-positive acute myeloid leukaemia. Leukemia Research 26(11), pp. 997-1005. (10.1016/S0145-2126(02)00049-8)
- Robinson, L. G., Owen-Jones, C. E., Austin, S., Mills, K. I. and Burnett, A. K. 1999. Relationship between PCR status following chemotherapy and outcome in t(8;21) positive acute myeloid leukaemia [Abstract]. British Journal of Haematology 105(Sup.1), pp. 67.
- Austin, S. J., Robinson, L. G., Owen-Jones, C. E., Mills, K. I. and Burnett, A. 1999. Quantitation of AML1-ETO fusion transcripts in t(8;21) positive AML using real-time light cycler PCR [Abstract]. British Journal of Haematology 105, pp. 76.
- Robinson, L. G. et al. 1999. Altered gene expression in 32D cells expressing the AML1A gene or AML1-ETO fusion gene. British Journal of Haematology 105(Supp1), pp. 103-103.
- Owen-Jones, C., Robinson, L. G., Austin, S., Bailey-Wood, R., Agar, A., Mills, K. and Burnett, A. K. 1999. Absence of leukaemic cell contamination of bone marrow (BM) and peripheral blood stem cell (PBSC) harvests as detected by PCR in good risk Acute Myeloid Leukaemia. British Journal of Haematology 105(Supp 1), pp. 56-56.
- Austin, S. J., Robinson, L. G., Owen-Jones, C. E., Mills, K. I. and Burnett, A. K. 1998. Real-time PCR (lightcycler technology) for quantitation of AML1-ETO fusion transcripts in t(8;21) positive AML. Blood 92(10), pp. 75A-75A.
- Robinson, L. G., Austin, S. J., Owen-Jones, C. E., Al-Sabah, A., Bailey-Wood, R., Mills, K. I. and Burnett, A. K. 1998. Prognostic value of IgH rearrangement detection in peripheral blood stem cell (PBSC) harvests of patients with Multiple Myeloma undergoing PBSC transplantation [Abstract]. British Journal of Haematology 102(1), pp. 292-293. (10.1111/j.1365-2141.1998.tb08997.x)
- Robinson, L. G., Austin, S. J., Owen-Jones, C. E., Langabeer, S. E., Linch, D. C., Mills, K. I. and Burnett, A. 1998. Multiplex PCR for the detection of prognostically important gene rearrangements in acute myeloid leukaemia [Abstract]. British Journal of Haematology 101(S), pp. 21.
- Robinson, L., Owen-Jones, C. E., Bowen, D., Langabeer, S., Linch, D., Mills, K. I. and Burnett, A. K. 1997. Multiplex PCR for the detection of prognostically important chromosomal abnormalities in acute myeloid leukaemia [Abstract]. Blood 90(10), pp. 276.
Gosodiad
- Owen-Jones, C. E. 2004. Stem cells in human oral epithelium. PhD Thesis, Cardiff University.
Bywgraffiad
Addysg a chymwysterau:
1999 - 2004: Coleg Meddygaeth Prifysgol Cymru, Adran Iechyd Deintyddol Oedolion - Ph.D. o'r enw Bôn-gelloedd mewn epitheliwm llafar dynol (a ariennir gan yr MRC), a ddyfarnwyd Chwefror 2004. Ymchwiliwyd i sefyllfa bôn-gelloedd neu barthau bôn-gelloedd mewn epitheliwm llafar yn vivo, ac yn vitro gan ddefnyddio diwylliant celloedd ac mewn model tebyg i groen (diwylliant organodetig), gan ddefnyddio amrywiaeth o dechnegau.
Mai 2000: Coleg Meddygaeth Prifysgol Cymru, Diploma mewn Dulliau Biofeddygol (Pass) - Ymdriniwyd ag ystod amrywiol o ddulliau labordy a phynciau TG.
1992 - 1995: Prifysgol Cymru Aberystwyth, B.Sc. (Anrh.) mewn Geneteg a Biocemeg (Dosbarth 2.1) - Astudiodd amaethyddiaeth, biocemeg, organebau a phrosesau biolegol, biotechnoleg, geneteg, biocemeg feddygol, amrywiaeth ficrobaidd a microbioleg.
Trosolwg gyrfa:
Gorffennaf 2007 – hyd yn hyn: Canolfan Ymchwil Treialon - Rheolwr Treial.
Mai 2007 i Gorffennaf 2007: Oxford Pharmaceutical Sciences - Ysgrifennwr Meddygol
Hydref 2004 i Mawrth 2007: Marix Drug Development Limited, Llantrisant - Rheolwr Prosiect.
Ebrill 1996 i Fedi 1999: Adran Haematoleg, Coleg Meddygaeth Prifysgol Cymru, Caerdydd - Technegydd Ymchwil.
Contact Details
Owen-JonesCE@caerdydd.ac.uk
+44 29206 87601
Neuadd Meirionnydd, Ystafell 708B, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4YS
+44 29206 87601
Neuadd Meirionnydd, Ystafell 708B, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4YS
