![Timothy Pickles BSc, MSc, PhD](https://profiles-cardiff.imgix.net/attachments/3628?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Dr Timothy Pickles
(e/fe)
BSc, MSc, PhD
Cymrawd Ymchwil mewn Ystadegau
- Sylwebydd y cyfryngau
- Ar gael fel goruchwyliwr ôl-raddedig
Trosolwyg
Themâu Ymchwil
Rwy'n gweithio yn y Ganolfan Ymchwil Treialon (CTR) ym Mhrifysgol Caerdydd fel Cymrawd Ymchwil mewn Ystadegau. Dyfarnwyd Cymrodoriaeth Ddoethurol NIHR Ymchwil Iechyd a Gofal Cymru i mi yn 2019 i gwblhau PhD ar seicometreg, mesurau canlyniadau a adroddwyd gan gleifion (PROMs), damcaniaeth mesur Rash a phrawf ymaddasol cyfrifiadurol ym maes Gweithgarwch Clefyd Arthritis Rheumatoid. Cefais fy goruchwylio gan yr Athro Ernest Choy (Prifysgol Caerdydd), Dr Mike Horton (Prifysgol Leeds), Dr Karl Bang Christensen (Prifysgol Copenhagen), Dr Rhiannon Phillips (Prifysgol Metropolitan Caerdydd) a Dr David Gillespie (Prifysgol Caerdydd).
Mae gen i Wobr Camau Nesaf Ymchwil Iechyd a Gofal Cymru i barhau â'r ymchwil o fy PhD, a elwir yn astudiaeth PLAN-HERACLES.
Yn flaenorol, rwyf wedi dal swyddi yng Nghanolfan Triniaeth a Gwerthuso Arthritis Arbrofol Rhanbarthol Caerdydd (CREATE) ac wedi cael secondiad yn yr Ysgol Deintyddiaeth, a oedd yn ogystal ag ymchwil, yn cynnwys ystadegau addysgu ac SPSS i fyfyrwyr BDS, a darparu cefnogaeth ystadegol i fyfyrwyr MOrth a PhD.
Tan 2019, roedd fy ngwaith yn CTR yn ymwneud yn bennaf â bod yn ystadegydd ar dreialon clinigol lluosog a gwahanol, ar draws llawer o ddisgyblaethau amrywiol. Rwyf wedi datblygu diddordeb mewn diabetes, heintiau'r llwybr wrinol, rhewmatoleg a chyflyrau croen, yn ogystal â charïau deintyddol o fy ngwaith blaenorol yn yr Ysgol Ddeintyddiaeth. Yr ymyriadau yr wyf wedi canolbwyntio arnynt yw cwnsela newid ymddygiad, offer rhannu penderfyniadau a dyfeisiau/cymhorthion ar gyfer rhagnodi gwrthfiotig priodol.
Yn fy rôl yng nghanolfan CREATE, roeddwn yn ymchwilio i ddefnyddio methodoleg treialon clinigol cam cynnar ym maes rhewmatoleg. Roeddwn eisoes wedi dechrau ymchwilio i dechnegau i archwilio priodweddau seicometrig gwahanol Offerynnau Ansawdd Bywyd, ac roeddwn yn ffodus i dreulio fy nhraethawd hir MSc yn dysgu am, ac yn ymgymryd â nhw, dadansoddiadau Rasch, sy'n thema ymchwil barhaus.
Yn dilyn cais llwyddiannus, ymunais â charfan 2019 Crucible GW4 ar Arloesi Digidol a chefais gyllid sbarduno ar gyfer astudiaeth GW4-PATH.
Mae gen i BSc (Anrh) Gwyddorau Naturiol o Brifysgol Caerfaddon, MSc (rhagoriaeth) mewn Ymchwil Weithredol ac Ystadegau Appiled o Brifysgol Caerdydd a PhD mewn Meddygaeth o Brifysgol Caerdydd.
Cysylltiadau pellach:
Astudiaeth SOCRATES: https://www.cardiff.ac.uk/centre-for-trials-research/research/studies-and-trials/view/socrates
Astudiaeth SOCRATES: https://healthandcareresearchwales.org/researchers/our-funded-projects/patient-reported-outcome-measures-rheumatoid-arthritis-symptom
Astudiaeth PLAN-HERACLES: https://www.cardiff.ac.uk/centre-for-trials-research/research/studies-and-trials/view/plan-heracles
SOCRATES a PLAN-HERACLES NRAS tudalen: https://nras.org.uk/resource/socrates_plan-heracles/
Blogiau CTR: https://blogs.cardiff.ac.uk/centre-for-trials-research/author/wpptep/
Proffil Cyfadran Ymchwil Iechyd a Gofal Cymru: https://healthandcareresearchwales.org/pickles
GW4-LLWYBR: https://gw4.ac.uk/gw4-crucible-seed-projects-2019/
Blog GW4: https://gw4.ac.uk/experience-of-gw4-crucible-from-trepidation-to-triumph/
Tafarnau: https://publons.com/author/1193132/timothy-pickles#profile
Cyhoeddiad
2024
- Pattinson, R., Trialonis-Suthakaran, N., Pickles, T., Austin, J., FitzGerald, A., Augustin, M. and Bundy, C. 2024. Measurement properties and interpretability of the Patient-Reported Impact of Dermatological Diseases (PRIDD) measure. British Journal of Dermatology 191, pp. 936-948. (10.1093/bjd/ljae267)
- Pickles, T. and Ingram, J. R. 2024. Minimal important difference of pain numeric rating scale in patients with Hidradenitis suppurativa: results from THESEUS. British Journal of Dermatology (10.1093/bjd/ljae486)
- Pattinson, R., Trialonis-Suthakharan, N., Pickles, T., Austin, J., FitzGerald, A., Augustin, M. and Bundy, E. 2024. Further refinement of the Patient-Reported Impact of Dermatological Diseases (PRIDD) measure using classical test theory and item response theory. British Journal of Dermatology 190(5), pp. 718-728., article number: ljad487. (10.1093/bjd/ljad487)
- Chapman, L. S. et al. 2024. Evolving and evaluating the OMERACT fellows program: insights and implications from OMERACT 2023 fellows. Seminars in Arthritis and Rheumatism 65, article number: 152391. (10.1016/j.semarthrit.2024.152391)
- Pickles, T. et al. 2024. Exploring the complexities of pain phenotypes: OMERACT 2023 chronic pain working group workshop. Seminars in Arthritis and Rheumatism 64, article number: 152342. (10.1016/j.semarthrit.2023.152342)
- Pickles, T. 2024. Patient-reported Outcome Measures for Rheumatoid Arthritis Symptom Severity: development of a computer adaptive test from an item bank using Rasch measurement theory (SOCRATES). PhD Thesis, Cardiff University.
2023
- Bisson, J. et al. 2023. Pragmatic randomised controlled trial of guided self-help versus individual cognitive behavioural therapy with a trauma focus for post-traumatic stress disorder (RAPID). Health Technology Assessment 27, article number: 26. (10.3310/YTQW8336)
- Pickles, T., Horton, M., Christensen, K. B., Phillips, R., Gillespie, D., Mo, N. and Choy, E. 2023. P035 Patient-reported outcome measures for rheumatoid arthritis disease activity: using Rasch measurement theory to achieve more meaningful measurement. Rheumatology 62(Supp 2) (10.1093/rheumatology/kead104.076)
- Withers, K. et al. 2023. Proceedings of the 6th National Patient Reported Outcome Measures (PROMs) Annual UK Research Virtual Conference, Bridgend, Wales 2022. Quality of Life Research 32, pp. 1-21. (10.1007/s11136-023-03353-w)
- Sauchelli, S. et al. 2023. Public attitudes towards the use of novel technologies in their future healthcare: a UK survey. BMC Medical Informatics and Decision Making 23, article number: 38. (10.1186/s12911-023-02118-2)
- Pickles, T., Horton, M., Christensen, K. B., Phillips, R., Gillespie, D., Mo, N. and Choy, E. 2023. Patient reported outcome measures for rheumatoid arthritis disease activity: using Rasch measurement theory and cognitive interviewing to achieve more meaningful measurement. Presented at: ACR Convergence 2023, San Diego, 10-15 November 2023, Vol. 75. Vol. Supp 9.
- Watts, T. et al. 2023. The ASSISTANCE STUDY: Moral distress and psychological wellbeing of nurses during the COVID-19 pandemic. Presented at: Royal College of Nursing International Nursing Research Conference, Manchester University, 6-8 September 2023.
2022
- Lau, T. M. M., Lowe, J., Pickles, T., Hood, K., Kotecha, S. and Gillespie, D. 2022. AZTEC—azithromycin therapy for prevention of chronic lung disease of prematurity: a statistical analysis plan for clinical outcomes. Trials 23(1), article number: 704. (10.1186/s13063-022-06604-2)
- Bisson, J. I. et al. 2022. Guided, internet based, cognitive behavioural therapy for post-traumatic stress disorder: pragmatic, multicentre, randomised controlled non-inferiority trial (RAPID). BMJ 377, article number: e069405. (10.1136/bmj-2021-069405)
- Abbott, R. A. et al. 2022. Observational study to estimate the proportion of surgical site infection following excision of ulcerated skin tumours (OASIS study). Clinical and Experimental Dermatology 47(5), pp. 882-888. (10.1111/ced.15037)
- Pickles, T. et al. 2022. P089 Patient-reported outcome measures for rheumatoid arthritis disease activity: a systematic review following COSMIN guidelines. Presented at: British Society for Rheumatology Annual Conference 2022, Glasgow, Scotland, 25-27 April 2022Rheumatology Supplement 1, Vol. 61. pp. keac133.088., (10.1093/rheumatology/keac133.088)
- Pickles, T. et al. 2022. Patient reported outcome measures for rheumatoid arthritis disease activity: a systematic review following COSMIN guidelines. RMD Open 8(1), article number: e002093. (10.1136/rmdopen-2021-002093)
- Griffiths, C., Tollow, P., Cox, D., White, P., Pickles, T. and Harcourt, D. 2022. The CARe Burn Scale—Adult Form: Identifying the responsiveness and minimal important difference (MID) values of a Patient Reported Outcome Measure (PROM) to assess quality of life for adults with a burn injury. European Burn Journal 3(1), pp. 211-233. (10.3390/ebj3010019)
- Joshi, H. B. et al. 2022. Urinary stones and intervention quality of life (USIQoL): development and validation of a new core universal patient-reported outcome measure for urinary calculi. European Urology Focus 8(1), pp. 283-290. (10.1016/j.euf.2020.12.011)
- Pickering, D., Pickles, T. and Shiress, T. 2022. A study protocol to develop the domains of an observational well-being scale (WEBS) for non-verbal children and young people with cerebral palsy from using the Innowalk.. Presented at: National Patient Reported Outcome Measures, Online, 14 - 15 June 2022.
- Watts, T. et al. 2022. Addressing moral distress among nurses after the COVID-19 emergency: The ASSISTANCE study. Presented at: Canopi Synposium, Cardiff University, May 2022.
2021
- Griffiths, C., Tollow, P., Cox, D., White, P., Pickles, T. and Harcourt, D. 2021. Testing the responsiveness of and defining minimal important difference (MID) values for the CARe burn scales: patient-reported outcome measures to assess quality of life for children and young people affected by burn injuries, and their parents/caregivers. European Burn Journal 2(4), pp. 249-280. (10.3390/ebj2040019)
- Pattinson, R. L. et al. 2021. Patient-reported outcome measures in dermatology: a systematic review. Acta Dermato-Venereologica 101(9), article number: adv00559. (10.2340/00015555-3884)
- McCarroll, Z., Townson, J., Pickles, T., Gregory, J. W., Playle, R., Robling, M. and Hughes, D. 2021. Cost-effectiveness of home versus hospital management of children at onset of Type 1 Diabetes: The DECIDE randomised controlled trial. BMJ Open 11(5), article number: e043523. (10.1136/bmjopen-2020-043523)
- Bartlett, R., Acton, J., Ryan, B., Man, R., Pickles, T. and Nollett, C. 2021. Training results in increased practitioner confidence and identification of depression in people with low vision: a mixed methods study. Ophthalmic and Physiological Optics 41(2), pp. 316-330. (10.1111/opo.12788)
- Griffiths, C., Guest, E., Pickles, T., Hollèn, L., Grzeda, M., Tollow, P. and Harcourt, D. 2021. The development and validation of the CARe Burn Scale: Child Form: a parent-proxy-reported outcome measure assessing quality of life for children aged 8 years and under living with a burn injury. Quality of Life Research 30, pp. 239-250. (10.1007/s11136-020-02627-x)
2020
- Lowe, J. et al. 2020. Study protocol: azithromycin therapy for chronic lung disease of prematurity (AZTEC) - a randomised, placebo-controlled trial of azithromycin for the prevention of chronic lung disease of prematurity in preterm infants. BMJ Open 10(10), article number: e041528. (10.1136/bmjopen-2020-041528)
- Stampalija, T. et al. 2020. Fetal cerebral Doppler changes and outcome in late preterm fetal growth restriction: prospective cohort study. Ultrasound in Obstetrics and Gynecology 56(2), pp. 173-181. (10.1002/uog.22125)
- Bisson, J. I. et al. 2020. Randomised controlled trial of multi-modular motion-assisted memory desensitization and reconsolidation (3MDR) for male military veterans with treatment-resistant post-traumatic stress disorder. Acta Psychiatrica Scandinavica 142(2), pp. 141-151. (10.1111/acps.13200)
- Nollett, C., Bartlett, R., Man, R., Pickles, T., Ryan, B. and Acton, J. H. 2020. Barriers to integrating routine depression screening into community low vision rehabilitation services: a mixed methods study. BMC Psychiatry 20, pp. 419. (10.1186/s12888-020-02805-8)
2019
- Nollett, C., Bartlett, R., Man, R., Pickles, T., Ryan, B. and Acton, J. H. 2019. How do community-based eye care practitioners approach depression in patients with low vision? A mixed methods study. BMC Psychiatry 19(1), article number: 426. (10.1186/s12888-019-2387-x)
- Gregory, J. W. et al. 2019. Effectiveness of home or hospital initiation of treatment at diagnosis for children with type 1 diabetes (DECIDE trial): a multicentre individually randomised controlled trial. BMJ Open 9, article number: e032317. (10.1136/bmjopen-2019-032317)
- Bosanquet, D. et al. 2019. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): results from a randomised controlled feasibility trial. BMJ Open 9(11), article number: e029233. (10.1136/bmjopen-2019-029233)
- Pickles, T. et al. 2019. Adaptive trial designs in rheumatology: Report from the OMERACT Special Interest Group. Journal of Rheumatology 46(10), pp. 1406-1408., article number: jrheum.181054. (10.3899/jrheum.181054)
- Griffiths, C. et al. 2019. The development and validation of the CARe Burn Scale - Adult Form: a Patient Reported Outcome Measure (PROM) to assess quality of life for adults living with a burn injury. Journal of Burn Care and Research 40(36), pp. 312-326. (10.1093/jbcr/irz021)
- Morgan-Trimmer, S. et al. 2019. The acceptability of fluoride varnish and fissure sealant treatments in children aged 6-9 delivered in a school setting. Community Dental Health 36(1), pp. 33-38. (10.1922/CDH_4263Morgan-Trimmer06)
2018
- Cooksey, R. et al. 2018. Cardiovascular risk factors predicting cardiac events are different in patients with rheumatoid arthritis, psoriatic arthritis, and psoriasis. Seminars in Arthritis and Rheumatism 48(3), pp. 367-373. (10.1016/j.semarthrit.2018.03.005)
- Bosanquet, D. C. et al. 2018. Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. British Journal of Pain 12(4), pp. 257-258. (10.1177/2049463718800736)
- Pickles, T., Christensen, R., Tam, L., Simon, L. S. and Choy, E. H. 2018. Early phase and adaptive design clinical trials in rheumatoid arthritis: a systematic review of early phase trials. Rheumatology Advances in Practice 2(2), article number: rky045. (10.1093/rap/rky045)
- Butler, C. C. et al. 2018. Point-of-care urine culture for managing urinary tract infection in primary care: a randomised controlled trial of clinical and cost-effectiveness. British Journal of General Practice 68(669), pp. e268-e278. (10.3399/bjgp18X695285)
- Nollett, C. et al. 2018. Pragmatic RAndomised controlled trial of a trauma-focused guided self-help Programme versus InDividual trauma-focused cognitive Behavioural therapy for post-traumatic stress disorder (RAPID): trial protocol. BMC Psychiatry 18(1), article number: 77. (10.1186/s12888-018-1665-3)
- Ingram, J. et al. 2018. Levels of wound calprotectin and other inflammatory biomarkers aid in deciding which patients with a diabetic foot ulcer need antibiotic therapy (INDUCE study). Diabetic Medicine 35(2), pp. 255-261. (10.1111/dme.13431)
- Alhaidari, T. et al. 2018. Feasibility and acceptability of text messaging to support antenatal healthcare in Iraqi pregnant women: a pilot study. Journal of Perinatal Medicine 46(1), pp. 67-74. (10.1515/jpm-2016-0127)
2017
- Butler, C. C. et al. 2017. Variations in presentation, management, and patient outcomes of urinary tract infection: a prospective four-country primary care observational cohort study. British Journal of General Practice 67(665), pp. e830-e841. (10.3399/bjgp17X693641)
- Bosanquet, D. C. et al. 2017. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 18, article number: 629. (10.1186/s13063-017-2357-x)
- White, J. et al. 2017. Adaptation of the ASSIST peer-led smoking intervention to deliver information from the Talk to FRANK drug education website (ASSIST+FRANK): a pilot cluster-randomised controlled trial. The Lancet 390(S3), pp. S1. (10.1016/S0140-6736(17)32936-7)
- White, J. et al. 2017. Adapting the ASSIST model of informal peer-led intervention delivery to the Talk to FRANK drug prevention programme in UK secondary schools (ASSIST?+FRANK): intervention development, refinement and a pilot cluster randomised controlled trial. Public Health Research 5(7), pp. 1-126. (10.3310/phr05070)
- Hullegie, S. et al. 2017. Clinicians' interpretations of point of care urine culture versus laboratory culture results: analysis from the four-country POETIC trial of diagnosis of uncomplicated urinary tract infection in primary care. Family Practice 34(4), pp. 392-399. (10.1093/fampra/cmx009)
- Chestnutt, I. G. et al. 2017. Fissure seal or fluoride varnish? A randomised trial of their relative effectiveness. Journal of Dental Research 96(7), pp. 754-761. (10.1177/0022034517702094)
- Chestnutt, I. G. et al. 2017. Seal or Varnish? A randomised controlled trial to determine the relative cost and effectiveness of pit and fissure sealant and fluoride varnish in preventing dental decay. Health Technology Assessment 21(21), pp. 1-256. (10.3310/hta21210)
- Chalumeau, M. et al. 2017. Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: diagnostic cohort study. PLoS ONE 12(2), article number: e0171113. (10.1371/journal.pone.0171113)
2016
- Hay, A. D. et al. 2016. Improving the diagnosis and treatment of urinary tract infection in young children in primary care: results from the DUTY prospective diagnostic cohort study. Annals of Family Medicine 14(4), pp. 325-336. (10.1370/afm.1954)
- Hay, A. D. et al. 2016. The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the diagnosis of urinary tract infection in children presenting to primary care with an acute illness. Health Technology Assessment 20(51) (10.3310/hta20510)
- Butler, C. C. et al. 2016. Nappy pad urine samples for investigation and treatment of UTI in young children: the 'DUTY' prospective diagnostic cohort study. British Journal of General Practice 66(648), pp. e516-e524. (10.3399/bjgp16X685873)
- Elwyn, G. et al. 2016. Supporting shared decision making using an Option Grid for osteoarthritis of the knee in an interface musculoskeletal clinic: a stepped wedge trial. Patient Education and Counseling 99(4), pp. 571-577. (10.1016/j.pec.2015.10.011)
- Atwan, A., Ingram, J. R., Abbott, R., Kelson, M. J., Pickles, T. E., Bauer, A. and Piguet, V. 2016. Oral fumaric acid esters for psoriasis: abridged Cochrane systematic review including GRADE assessments. British Journal of Dermatology 175(5), pp. 873-881. (10.1111/bjd.14676)
- Butler, C. C. et al. 2016. Empiric antibiotic treatment for urinary tract infection in preschool children: susceptibilities of urine sample isolates. Family Practice 33(2), pp. 127-132. (10.1093/fampra/cmv104)
2015
- Randell, E., Pickles, T., Simpson, S. A., Spanou, C., McCambridge, J., Hood, K. and Butler, C. C. 2015. Eligibility for interventions, co-occurrence and risk factors for unhealthy behaviours in patients consulting for routine primary care: results from the Pre-Empt study. BMC Family Practice 16, article number: 133. (10.1186/s12875-015-0359-x)
- Gobat, N. H., Kinnersley, P., Gregory, J. W., Pickles, T. E., Hood, K. and Robling, M. R. 2015. Measuring clinical skills in agenda-mapping (EAGL-I). Patient Education and Counseling 98(10), pp. 1214-1221. (10.1016/j.pec.2015.06.018)
- Al Ali, A. et al. 2015. The influence of snoring, mouth breathing and apnoea on facial morphology in late childhood: a three-dimensional study. BMJ Open 5(9), article number: e009027. (10.1136/bmjopen-2015-009027)
- Atwan, A., Ingram, J., Abbott, R., Kelson, M., Pickles, T., Bauer, A. and Piguet, V. 2015. Oral fumaric acid esters for psoriasis. Cochrane Database of Systematic Reviews(8), article number: CD010497. (10.1002/14651858.CD010497.pub2)
- Butler, C. C. et al. 2015. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. British Journal of General Practice 65(633), pp. e217-e223. (10.3399/bjgp15X684361)
2014
- Bates, J. et al. 2014. Point of care testing for urinary tract infection in primary care (POETIC): protocol for a randomised controlled trial of the clinical and cost effectiveness of FLEXICULT (TM) informed management of uncomplicated UTI in primary care. BMC Family Practice 15, pp. -., article number: 187. (10.1186/s12875-014-0187-4)
- Al Ali, A. et al. 2014. A three-dimensional analysis of the effect of atopy on face shape. European Journal of Orthodontics 36(5), pp. 506-511. (10.1093/ejo/cjs107)
- Haddad, N. S. et al. 2014. A feasibility study of mobile phone text messaging to support education and management of type 2 diabetes in Iraq. Diabetes Technology & Therapeutics 16(7), pp. 454-459. (10.1089/dia.2013.0272)
- Lowes, L. M. et al. 2014. Late-breaking abstract. [LB1 Delivering early care in diabetes evaluation: the DECIDE Study. Hospital versus home management at diagnosis in childhood diabetes: a comparison of psychological, social, physical and economic outcomes]. Diabetic Medicine 31(s1), pp. 184. (10.1111/dme.12408)
- Marrin, K. et al. 2014. Option Grids to facilitate shared decision making for patients with Osteoarthritis of the knee: protocol for a single site, efficacy trial. BMC Health Services Research 14, article number: 160. (10.1186/1472-6963-14-160)
- Lowes, L. M. et al. 2014. Delivering early care in diabetes evaluation: the DECIDE study. Hospital versus home management at diagnosis in childhood diabetes: a comparison of psychological, social, physical and economic outcomes. Presented at: Diabetes UK Professional Conference 2014, Liverpool, UK, 5-7 March 2014.
2013
- Pickles, T., Playle, R., Hood, K., Gillard, J. and Robling, M. 2013. Rasch analysis of the PedsQL 3.0 diabetes module. [Abstract]. Trials 14(S1), article number: 40. (10.1186/1745-6215-14-S1-O40)
- Bates, J. et al. 2013. Effects of an optimised POCT guided diagnostic and treatment strategy for symptoms of uncomplicated UTI on use of appropriate antibiotics and uptake into primary care practice. [Abstract]. Trials 14(S1), pp. -., article number: P10. (10.1186/1745-6215-14-S1-P10)
- Butler, C. C. et al. 2013. Training practitioners to deliver opportunistic multiple behaviour change counselling in primary care: a cluster randomised trial. BMJ 346, article number: f1191. (10.1136/bmj.f1191)
- Edwards, A. G., Naik, G., Ahmed, H., Elwyn, G., Pickles, T. E., Hood, K. and Playle, R. A. 2013. Personalised risk communication for informed decision making about taking screening tests. Cochrane Database of Systematic Reviews 2013(2), article number: CD001865. (10.1002/14651858.CD001865.pub3)
- Waldron, C. et al. 2013. Recruitment to diagnosis of urinary tract infections in young children (DUTY) study: an evaluation of the successful methods used in a primary care, prospective cohort study. [Abstract]. Trials 14(S1), pp. -., article number: P37. (10.1186/1745-6215-14-S1-P37)
2012
- Chestnutt, I. G. et al. 2012. Protocol for 'Seal or Varnish' (SoV) trial: A randomised controlled trial to measure the relative cost and effectiveness of pit and fissure sealants and fluoride varnish in preventing dental decay. BMC Oral Health 12(1), pp. 51-62. (10.1186/1472-6831-12-51)
- Robling, M. R. et al. 2012. The effect of the Talking Diabetes consulting skills intervention on glycaemic control and quality of life in children with type 1 diabetes: cluster randomised controlled trial (DEPICTED study). British Medical Journal 344, article number: e2359. (10.1136/bmj.e2359)
2011
- Gregory, J. W. et al. 2011. Development and evaluation by a cluster randomised trial of a psychosocial intervention in children and teenagers experiencing diabetes: The DEPICTED study. Health Technology Assessment 15(29), pp. 1-202. (10.3310/hta15290)
2010
- Spanou, C. et al. 2010. Preventing disease through opportunistic, rapid engagement by primary care teams using behaviour change counselling (PRE-EMPT): protocol for a general practice-based cluster randomised trial. BMC Family Practice 11(1), pp. 69. (10.1186/1471-2296-11-69)
Articles
- Pattinson, R., Trialonis-Suthakaran, N., Pickles, T., Austin, J., FitzGerald, A., Augustin, M. and Bundy, C. 2024. Measurement properties and interpretability of the Patient-Reported Impact of Dermatological Diseases (PRIDD) measure. British Journal of Dermatology 191, pp. 936-948. (10.1093/bjd/ljae267)
- Pickles, T. and Ingram, J. R. 2024. Minimal important difference of pain numeric rating scale in patients with Hidradenitis suppurativa: results from THESEUS. British Journal of Dermatology (10.1093/bjd/ljae486)
- Pattinson, R., Trialonis-Suthakharan, N., Pickles, T., Austin, J., FitzGerald, A., Augustin, M. and Bundy, E. 2024. Further refinement of the Patient-Reported Impact of Dermatological Diseases (PRIDD) measure using classical test theory and item response theory. British Journal of Dermatology 190(5), pp. 718-728., article number: ljad487. (10.1093/bjd/ljad487)
- Chapman, L. S. et al. 2024. Evolving and evaluating the OMERACT fellows program: insights and implications from OMERACT 2023 fellows. Seminars in Arthritis and Rheumatism 65, article number: 152391. (10.1016/j.semarthrit.2024.152391)
- Pickles, T. et al. 2024. Exploring the complexities of pain phenotypes: OMERACT 2023 chronic pain working group workshop. Seminars in Arthritis and Rheumatism 64, article number: 152342. (10.1016/j.semarthrit.2023.152342)
- Bisson, J. et al. 2023. Pragmatic randomised controlled trial of guided self-help versus individual cognitive behavioural therapy with a trauma focus for post-traumatic stress disorder (RAPID). Health Technology Assessment 27, article number: 26. (10.3310/YTQW8336)
- Pickles, T., Horton, M., Christensen, K. B., Phillips, R., Gillespie, D., Mo, N. and Choy, E. 2023. P035 Patient-reported outcome measures for rheumatoid arthritis disease activity: using Rasch measurement theory to achieve more meaningful measurement. Rheumatology 62(Supp 2) (10.1093/rheumatology/kead104.076)
- Withers, K. et al. 2023. Proceedings of the 6th National Patient Reported Outcome Measures (PROMs) Annual UK Research Virtual Conference, Bridgend, Wales 2022. Quality of Life Research 32, pp. 1-21. (10.1007/s11136-023-03353-w)
- Sauchelli, S. et al. 2023. Public attitudes towards the use of novel technologies in their future healthcare: a UK survey. BMC Medical Informatics and Decision Making 23, article number: 38. (10.1186/s12911-023-02118-2)
- Lau, T. M. M., Lowe, J., Pickles, T., Hood, K., Kotecha, S. and Gillespie, D. 2022. AZTEC—azithromycin therapy for prevention of chronic lung disease of prematurity: a statistical analysis plan for clinical outcomes. Trials 23(1), article number: 704. (10.1186/s13063-022-06604-2)
- Bisson, J. I. et al. 2022. Guided, internet based, cognitive behavioural therapy for post-traumatic stress disorder: pragmatic, multicentre, randomised controlled non-inferiority trial (RAPID). BMJ 377, article number: e069405. (10.1136/bmj-2021-069405)
- Abbott, R. A. et al. 2022. Observational study to estimate the proportion of surgical site infection following excision of ulcerated skin tumours (OASIS study). Clinical and Experimental Dermatology 47(5), pp. 882-888. (10.1111/ced.15037)
- Pickles, T. et al. 2022. Patient reported outcome measures for rheumatoid arthritis disease activity: a systematic review following COSMIN guidelines. RMD Open 8(1), article number: e002093. (10.1136/rmdopen-2021-002093)
- Griffiths, C., Tollow, P., Cox, D., White, P., Pickles, T. and Harcourt, D. 2022. The CARe Burn Scale—Adult Form: Identifying the responsiveness and minimal important difference (MID) values of a Patient Reported Outcome Measure (PROM) to assess quality of life for adults with a burn injury. European Burn Journal 3(1), pp. 211-233. (10.3390/ebj3010019)
- Joshi, H. B. et al. 2022. Urinary stones and intervention quality of life (USIQoL): development and validation of a new core universal patient-reported outcome measure for urinary calculi. European Urology Focus 8(1), pp. 283-290. (10.1016/j.euf.2020.12.011)
- Griffiths, C., Tollow, P., Cox, D., White, P., Pickles, T. and Harcourt, D. 2021. Testing the responsiveness of and defining minimal important difference (MID) values for the CARe burn scales: patient-reported outcome measures to assess quality of life for children and young people affected by burn injuries, and their parents/caregivers. European Burn Journal 2(4), pp. 249-280. (10.3390/ebj2040019)
- Pattinson, R. L. et al. 2021. Patient-reported outcome measures in dermatology: a systematic review. Acta Dermato-Venereologica 101(9), article number: adv00559. (10.2340/00015555-3884)
- McCarroll, Z., Townson, J., Pickles, T., Gregory, J. W., Playle, R., Robling, M. and Hughes, D. 2021. Cost-effectiveness of home versus hospital management of children at onset of Type 1 Diabetes: The DECIDE randomised controlled trial. BMJ Open 11(5), article number: e043523. (10.1136/bmjopen-2020-043523)
- Bartlett, R., Acton, J., Ryan, B., Man, R., Pickles, T. and Nollett, C. 2021. Training results in increased practitioner confidence and identification of depression in people with low vision: a mixed methods study. Ophthalmic and Physiological Optics 41(2), pp. 316-330. (10.1111/opo.12788)
- Griffiths, C., Guest, E., Pickles, T., Hollèn, L., Grzeda, M., Tollow, P. and Harcourt, D. 2021. The development and validation of the CARe Burn Scale: Child Form: a parent-proxy-reported outcome measure assessing quality of life for children aged 8 years and under living with a burn injury. Quality of Life Research 30, pp. 239-250. (10.1007/s11136-020-02627-x)
- Lowe, J. et al. 2020. Study protocol: azithromycin therapy for chronic lung disease of prematurity (AZTEC) - a randomised, placebo-controlled trial of azithromycin for the prevention of chronic lung disease of prematurity in preterm infants. BMJ Open 10(10), article number: e041528. (10.1136/bmjopen-2020-041528)
- Stampalija, T. et al. 2020. Fetal cerebral Doppler changes and outcome in late preterm fetal growth restriction: prospective cohort study. Ultrasound in Obstetrics and Gynecology 56(2), pp. 173-181. (10.1002/uog.22125)
- Bisson, J. I. et al. 2020. Randomised controlled trial of multi-modular motion-assisted memory desensitization and reconsolidation (3MDR) for male military veterans with treatment-resistant post-traumatic stress disorder. Acta Psychiatrica Scandinavica 142(2), pp. 141-151. (10.1111/acps.13200)
- Nollett, C., Bartlett, R., Man, R., Pickles, T., Ryan, B. and Acton, J. H. 2020. Barriers to integrating routine depression screening into community low vision rehabilitation services: a mixed methods study. BMC Psychiatry 20, pp. 419. (10.1186/s12888-020-02805-8)
- Nollett, C., Bartlett, R., Man, R., Pickles, T., Ryan, B. and Acton, J. H. 2019. How do community-based eye care practitioners approach depression in patients with low vision? A mixed methods study. BMC Psychiatry 19(1), article number: 426. (10.1186/s12888-019-2387-x)
- Gregory, J. W. et al. 2019. Effectiveness of home or hospital initiation of treatment at diagnosis for children with type 1 diabetes (DECIDE trial): a multicentre individually randomised controlled trial. BMJ Open 9, article number: e032317. (10.1136/bmjopen-2019-032317)
- Bosanquet, D. et al. 2019. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): results from a randomised controlled feasibility trial. BMJ Open 9(11), article number: e029233. (10.1136/bmjopen-2019-029233)
- Pickles, T. et al. 2019. Adaptive trial designs in rheumatology: Report from the OMERACT Special Interest Group. Journal of Rheumatology 46(10), pp. 1406-1408., article number: jrheum.181054. (10.3899/jrheum.181054)
- Griffiths, C. et al. 2019. The development and validation of the CARe Burn Scale - Adult Form: a Patient Reported Outcome Measure (PROM) to assess quality of life for adults living with a burn injury. Journal of Burn Care and Research 40(36), pp. 312-326. (10.1093/jbcr/irz021)
- Morgan-Trimmer, S. et al. 2019. The acceptability of fluoride varnish and fissure sealant treatments in children aged 6-9 delivered in a school setting. Community Dental Health 36(1), pp. 33-38. (10.1922/CDH_4263Morgan-Trimmer06)
- Cooksey, R. et al. 2018. Cardiovascular risk factors predicting cardiac events are different in patients with rheumatoid arthritis, psoriatic arthritis, and psoriasis. Seminars in Arthritis and Rheumatism 48(3), pp. 367-373. (10.1016/j.semarthrit.2018.03.005)
- Bosanquet, D. C. et al. 2018. Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. British Journal of Pain 12(4), pp. 257-258. (10.1177/2049463718800736)
- Pickles, T., Christensen, R., Tam, L., Simon, L. S. and Choy, E. H. 2018. Early phase and adaptive design clinical trials in rheumatoid arthritis: a systematic review of early phase trials. Rheumatology Advances in Practice 2(2), article number: rky045. (10.1093/rap/rky045)
- Butler, C. C. et al. 2018. Point-of-care urine culture for managing urinary tract infection in primary care: a randomised controlled trial of clinical and cost-effectiveness. British Journal of General Practice 68(669), pp. e268-e278. (10.3399/bjgp18X695285)
- Nollett, C. et al. 2018. Pragmatic RAndomised controlled trial of a trauma-focused guided self-help Programme versus InDividual trauma-focused cognitive Behavioural therapy for post-traumatic stress disorder (RAPID): trial protocol. BMC Psychiatry 18(1), article number: 77. (10.1186/s12888-018-1665-3)
- Ingram, J. et al. 2018. Levels of wound calprotectin and other inflammatory biomarkers aid in deciding which patients with a diabetic foot ulcer need antibiotic therapy (INDUCE study). Diabetic Medicine 35(2), pp. 255-261. (10.1111/dme.13431)
- Alhaidari, T. et al. 2018. Feasibility and acceptability of text messaging to support antenatal healthcare in Iraqi pregnant women: a pilot study. Journal of Perinatal Medicine 46(1), pp. 67-74. (10.1515/jpm-2016-0127)
- Butler, C. C. et al. 2017. Variations in presentation, management, and patient outcomes of urinary tract infection: a prospective four-country primary care observational cohort study. British Journal of General Practice 67(665), pp. e830-e841. (10.3399/bjgp17X693641)
- Bosanquet, D. C. et al. 2017. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 18, article number: 629. (10.1186/s13063-017-2357-x)
- White, J. et al. 2017. Adaptation of the ASSIST peer-led smoking intervention to deliver information from the Talk to FRANK drug education website (ASSIST+FRANK): a pilot cluster-randomised controlled trial. The Lancet 390(S3), pp. S1. (10.1016/S0140-6736(17)32936-7)
- White, J. et al. 2017. Adapting the ASSIST model of informal peer-led intervention delivery to the Talk to FRANK drug prevention programme in UK secondary schools (ASSIST?+FRANK): intervention development, refinement and a pilot cluster randomised controlled trial. Public Health Research 5(7), pp. 1-126. (10.3310/phr05070)
- Hullegie, S. et al. 2017. Clinicians' interpretations of point of care urine culture versus laboratory culture results: analysis from the four-country POETIC trial of diagnosis of uncomplicated urinary tract infection in primary care. Family Practice 34(4), pp. 392-399. (10.1093/fampra/cmx009)
- Chestnutt, I. G. et al. 2017. Fissure seal or fluoride varnish? A randomised trial of their relative effectiveness. Journal of Dental Research 96(7), pp. 754-761. (10.1177/0022034517702094)
- Chestnutt, I. G. et al. 2017. Seal or Varnish? A randomised controlled trial to determine the relative cost and effectiveness of pit and fissure sealant and fluoride varnish in preventing dental decay. Health Technology Assessment 21(21), pp. 1-256. (10.3310/hta21210)
- Chalumeau, M. et al. 2017. Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: diagnostic cohort study. PLoS ONE 12(2), article number: e0171113. (10.1371/journal.pone.0171113)
- Hay, A. D. et al. 2016. Improving the diagnosis and treatment of urinary tract infection in young children in primary care: results from the DUTY prospective diagnostic cohort study. Annals of Family Medicine 14(4), pp. 325-336. (10.1370/afm.1954)
- Hay, A. D. et al. 2016. The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the diagnosis of urinary tract infection in children presenting to primary care with an acute illness. Health Technology Assessment 20(51) (10.3310/hta20510)
- Butler, C. C. et al. 2016. Nappy pad urine samples for investigation and treatment of UTI in young children: the 'DUTY' prospective diagnostic cohort study. British Journal of General Practice 66(648), pp. e516-e524. (10.3399/bjgp16X685873)
- Elwyn, G. et al. 2016. Supporting shared decision making using an Option Grid for osteoarthritis of the knee in an interface musculoskeletal clinic: a stepped wedge trial. Patient Education and Counseling 99(4), pp. 571-577. (10.1016/j.pec.2015.10.011)
- Atwan, A., Ingram, J. R., Abbott, R., Kelson, M. J., Pickles, T. E., Bauer, A. and Piguet, V. 2016. Oral fumaric acid esters for psoriasis: abridged Cochrane systematic review including GRADE assessments. British Journal of Dermatology 175(5), pp. 873-881. (10.1111/bjd.14676)
- Butler, C. C. et al. 2016. Empiric antibiotic treatment for urinary tract infection in preschool children: susceptibilities of urine sample isolates. Family Practice 33(2), pp. 127-132. (10.1093/fampra/cmv104)
- Randell, E., Pickles, T., Simpson, S. A., Spanou, C., McCambridge, J., Hood, K. and Butler, C. C. 2015. Eligibility for interventions, co-occurrence and risk factors for unhealthy behaviours in patients consulting for routine primary care: results from the Pre-Empt study. BMC Family Practice 16, article number: 133. (10.1186/s12875-015-0359-x)
- Gobat, N. H., Kinnersley, P., Gregory, J. W., Pickles, T. E., Hood, K. and Robling, M. R. 2015. Measuring clinical skills in agenda-mapping (EAGL-I). Patient Education and Counseling 98(10), pp. 1214-1221. (10.1016/j.pec.2015.06.018)
- Al Ali, A. et al. 2015. The influence of snoring, mouth breathing and apnoea on facial morphology in late childhood: a three-dimensional study. BMJ Open 5(9), article number: e009027. (10.1136/bmjopen-2015-009027)
- Atwan, A., Ingram, J., Abbott, R., Kelson, M., Pickles, T., Bauer, A. and Piguet, V. 2015. Oral fumaric acid esters for psoriasis. Cochrane Database of Systematic Reviews(8), article number: CD010497. (10.1002/14651858.CD010497.pub2)
- Butler, C. C. et al. 2015. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. British Journal of General Practice 65(633), pp. e217-e223. (10.3399/bjgp15X684361)
- Bates, J. et al. 2014. Point of care testing for urinary tract infection in primary care (POETIC): protocol for a randomised controlled trial of the clinical and cost effectiveness of FLEXICULT (TM) informed management of uncomplicated UTI in primary care. BMC Family Practice 15, pp. -., article number: 187. (10.1186/s12875-014-0187-4)
- Al Ali, A. et al. 2014. A three-dimensional analysis of the effect of atopy on face shape. European Journal of Orthodontics 36(5), pp. 506-511. (10.1093/ejo/cjs107)
- Haddad, N. S. et al. 2014. A feasibility study of mobile phone text messaging to support education and management of type 2 diabetes in Iraq. Diabetes Technology & Therapeutics 16(7), pp. 454-459. (10.1089/dia.2013.0272)
- Lowes, L. M. et al. 2014. Late-breaking abstract. [LB1 Delivering early care in diabetes evaluation: the DECIDE Study. Hospital versus home management at diagnosis in childhood diabetes: a comparison of psychological, social, physical and economic outcomes]. Diabetic Medicine 31(s1), pp. 184. (10.1111/dme.12408)
- Marrin, K. et al. 2014. Option Grids to facilitate shared decision making for patients with Osteoarthritis of the knee: protocol for a single site, efficacy trial. BMC Health Services Research 14, article number: 160. (10.1186/1472-6963-14-160)
- Pickles, T., Playle, R., Hood, K., Gillard, J. and Robling, M. 2013. Rasch analysis of the PedsQL 3.0 diabetes module. [Abstract]. Trials 14(S1), article number: 40. (10.1186/1745-6215-14-S1-O40)
- Bates, J. et al. 2013. Effects of an optimised POCT guided diagnostic and treatment strategy for symptoms of uncomplicated UTI on use of appropriate antibiotics and uptake into primary care practice. [Abstract]. Trials 14(S1), pp. -., article number: P10. (10.1186/1745-6215-14-S1-P10)
- Butler, C. C. et al. 2013. Training practitioners to deliver opportunistic multiple behaviour change counselling in primary care: a cluster randomised trial. BMJ 346, article number: f1191. (10.1136/bmj.f1191)
- Edwards, A. G., Naik, G., Ahmed, H., Elwyn, G., Pickles, T. E., Hood, K. and Playle, R. A. 2013. Personalised risk communication for informed decision making about taking screening tests. Cochrane Database of Systematic Reviews 2013(2), article number: CD001865. (10.1002/14651858.CD001865.pub3)
- Waldron, C. et al. 2013. Recruitment to diagnosis of urinary tract infections in young children (DUTY) study: an evaluation of the successful methods used in a primary care, prospective cohort study. [Abstract]. Trials 14(S1), pp. -., article number: P37. (10.1186/1745-6215-14-S1-P37)
- Chestnutt, I. G. et al. 2012. Protocol for 'Seal or Varnish' (SoV) trial: A randomised controlled trial to measure the relative cost and effectiveness of pit and fissure sealants and fluoride varnish in preventing dental decay. BMC Oral Health 12(1), pp. 51-62. (10.1186/1472-6831-12-51)
- Robling, M. R. et al. 2012. The effect of the Talking Diabetes consulting skills intervention on glycaemic control and quality of life in children with type 1 diabetes: cluster randomised controlled trial (DEPICTED study). British Medical Journal 344, article number: e2359. (10.1136/bmj.e2359)
- Gregory, J. W. et al. 2011. Development and evaluation by a cluster randomised trial of a psychosocial intervention in children and teenagers experiencing diabetes: The DEPICTED study. Health Technology Assessment 15(29), pp. 1-202. (10.3310/hta15290)
- Spanou, C. et al. 2010. Preventing disease through opportunistic, rapid engagement by primary care teams using behaviour change counselling (PRE-EMPT): protocol for a general practice-based cluster randomised trial. BMC Family Practice 11(1), pp. 69. (10.1186/1471-2296-11-69)
Conferences
- Pickles, T., Horton, M., Christensen, K. B., Phillips, R., Gillespie, D., Mo, N. and Choy, E. 2023. Patient reported outcome measures for rheumatoid arthritis disease activity: using Rasch measurement theory and cognitive interviewing to achieve more meaningful measurement. Presented at: ACR Convergence 2023, San Diego, 10-15 November 2023, Vol. 75. Vol. Supp 9.
- Watts, T. et al. 2023. The ASSISTANCE STUDY: Moral distress and psychological wellbeing of nurses during the COVID-19 pandemic. Presented at: Royal College of Nursing International Nursing Research Conference, Manchester University, 6-8 September 2023.
- Pickles, T. et al. 2022. P089 Patient-reported outcome measures for rheumatoid arthritis disease activity: a systematic review following COSMIN guidelines. Presented at: British Society for Rheumatology Annual Conference 2022, Glasgow, Scotland, 25-27 April 2022Rheumatology Supplement 1, Vol. 61. pp. keac133.088., (10.1093/rheumatology/keac133.088)
- Pickering, D., Pickles, T. and Shiress, T. 2022. A study protocol to develop the domains of an observational well-being scale (WEBS) for non-verbal children and young people with cerebral palsy from using the Innowalk.. Presented at: National Patient Reported Outcome Measures, Online, 14 - 15 June 2022.
- Watts, T. et al. 2022. Addressing moral distress among nurses after the COVID-19 emergency: The ASSISTANCE study. Presented at: Canopi Synposium, Cardiff University, May 2022.
- Lowes, L. M. et al. 2014. Delivering early care in diabetes evaluation: the DECIDE study. Hospital versus home management at diagnosis in childhood diabetes: a comparison of psychological, social, physical and economic outcomes. Presented at: Diabetes UK Professional Conference 2014, Liverpool, UK, 5-7 March 2014.
Thesis
- Pickles, T. 2024. Patient-reported Outcome Measures for Rheumatoid Arthritis Symptom Severity: development of a computer adaptive test from an item bank using Rasch measurement theory (SOCRATES). PhD Thesis, Cardiff University.
- Joshi, H. B. et al. 2022. Urinary stones and intervention quality of life (USIQoL): development and validation of a new core universal patient-reported outcome measure for urinary calculi. European Urology Focus 8(1), pp. 283-290. (10.1016/j.euf.2020.12.011)
- Robling, M. R. et al. 2012. The effect of the Talking Diabetes consulting skills intervention on glycaemic control and quality of life in children with type 1 diabetes: cluster randomised controlled trial (DEPICTED study). British Medical Journal 344, article number: e2359. (10.1136/bmj.e2359)
- Gregory, J. W. et al. 2011. Development and evaluation by a cluster randomised trial of a psychosocial intervention in children and teenagers experiencing diabetes: The DEPICTED study. Health Technology Assessment 15(29), pp. 1-202. (10.3310/hta15290)
Ymchwil
Rwyf wedi cwblhau Cymrodoriaeth Ddoethurol NIHR Ymchwil Iechyd a Gofal Cymru a PhD sy'n canolbwyntio ar seicometreg, mesurau canlyniadau a adroddwyd gan gleifion (PROMs), damcaniaeth mesur Rash a phrawf ymaddasol cyfrifiadurol ym maes Arthritis Rheumatoid.
Mae arthritis gwynegol (RA) yn arthritis llidiol cronig cyffredin sy'n cael ei nodweddu gan ddifrifoldeb symptom amrywiol a fflêrs rheolaidd, sy'n gofyn am addasiadau monitro parhaus a thriniaeth ddilynol dros amser. Mae monitro gweithgarwch clefydau (DA) yn safon gofal yn RA. Mae'r asesiadau DA presennol yn gofyn am brofion labordy a/neu fewnbwn gweithiwr gofal iechyd proffesiynol (HCP). Felly, efallai y bydd Mesurau Canlyniadau a Adroddir gan Gleifion (PROMs), sef offer a gwblheir gan gleifion i ganfod canfyddiadau o'u hiechyd, yn well. Fodd bynnag, nid oes consensws ar sut i fesur RA DA gan ddefnyddio PROM.
Mae monitro gweithgarwch clefydau (DA) yn safon gofal mewn Arthritis Rhewmatoid (RA). Mae'r asesiadau DA presennol yn gofyn am brofion labordy a/neu fewnbwn proffesiynol gofal iechyd. Felly, gall Mesurau Canlyniadau a Adroddir gan Gleifion (PROMs) fod yn well. Fodd bynnag, nid oes consensws ar sut i fesur RA DA gan ddefnyddio PROM.
Roeddwn yn anelu at asesu priodweddau mesur RA DA PROMs etifeddiaeth a Proms perthnasol eraill, a dechrau datblygu prom RA da newydd.
Defnyddiais sawl dull gan gynnwys adolygiad systematig yn dilyn Safonau Seiliedig ar COnsensus ar gyfer dewis canllawiau INtruments Mesur Iechyd (COSMIN), dadansoddiadau meintiol o ddata ar PROMs etifeddiaeth a gasglwyd mewn astudiaeth drawsdoriadol o bobl ag RA (pwRA) ar draws pedwar Bwrdd Iechyd Prifysgol De Cymru, dadansoddiadau thematig a chynnwys o gyfweliadau gwybyddol gyda pwRA a datblygu prawf addasol cyfrifiadurol.
Canfûm na ellir argymell unrhyw RA PROMs etifeddiaeth i'w defnyddio yn y dyfodol ac ni allai unrhyw PROMs etifeddiaeth ddangos tystiolaeth lawn sy'n addas i fodel theori mesur Rasch. Dangosais fod y parth byd-eang Cleifion yn ddau barth penodol o weithgarwch Clefydau ac iechyd cyffredinol. Gellir defnyddio 12 eitem ar draws parthau Poen, gweithgaredd Clefydau, Tynerwch a chwyddo, Gweithrediad corfforol a Stiffrwydd i fesur adeiladu RA DA. Sefydlais rywfaint o dystiolaeth gychwynnol o ddilysrwydd cynnwys ar gyfer yr eitemau hyn. Yn olaf, darganfyddais nad yw prawf addasol cyfrifiadurol yn darparu mantais fawr at ddibenion gweinyddu'r 12 eitem.
Mae fy nghanfyddiadau'n dangos y gellir mesur adeiladu RA DA gyda dim ond pum eitem, gydag un o bob un o'r meysydd Poen, Clefydau, Tynerwch a chwyddo, Gweithrediad corfforol a Stiffness. Y camau nesaf yw darganfod y ffordd orau o ddylunio'r pum eitem hyn a phrofi eu priodweddau mesur, cyn eu defnyddio fel rhan o offeryn monitro DA wythnosol.
Cynnwys cleifion a'r cyhoedd
Roedd pobl ag RA yn cymryd rhan drwy gydol oes y gymrodoriaeth hon, o helpu i ddylunio'r camau ymchwil, goruchwylio rhedeg y gymrodoriaeth, a helpu i ddeall ystyr y canlyniadau.
Cefais fy goruchwylio gan yr Athro Ernest Choy (Prifysgol Caerdydd), Dr Mike Horton (Prifysgol Leeds), Dr Karl Bang Christensen (Prifysgol Copenhagen), Dr Rhiannon Phillips (Prifysgol Metropolitan Caerdydd) a Dr David Gillespie (Prifysgol Caerdydd).
Bywgraffiad
Proffil Gyrfa
2009 - 2014: Cynorthwy-ydd Ymchwil mewn Ystadegau, Uned Treialon De Ddwyrain Cymru a'r Ysgol Deintyddiaeth, Prifysgol Caerdydd
2014 - 2019: Cydymaith Ymchwil mewn Ystadegau, Canolfan Ymchwil Treialon a Chanolfan Triniaeth a Gwerthuso Arthritis Arbrofol Rhanbarthol Caerdydd
2019 - 2024: Ymchwil Iechyd a Gofal Cymru Cymrawd Doethurol NIHR, Canolfan Ymchwil Treialon
2024 - presennol: Cymrawd Ymchwil mewn Ystadegau, Canolfan Ymchwil Treialon Ymchwil
Addysg a Chymwysterau
2009: Dosbarth1af BSc (Anrh) Gwyddorau Naturiol gyda Lleoliad Diwydiannol, Prifysgol Caerfaddon
2014: MSc (Rhagoriaeth) Ymchwil Weithredol ac Ystadegau Cymhwysol, Prifysgol Caerdydd
2024: PhD mewn Meddygaeth, Prifysgol Caerdydd
Proffil Addysgu
BDS Deintyddol Ystadegau Cyhoeddus Darlithoedd a Sesiynau SPSS
Anrhydeddau a dyfarniadau
GradStat, Y Gymdeithas Ystadegol Frenhinol, 2016
CStat, Y Gymdeithas Ystadegol Frenhinol, 2019
Ysgoloriaeth Deithio, Cynhadledd ISOQOL 2021, 2021
Aelodaethau proffesiynol
Aelod ISOQOL, cadeirydd etholedig ISOQOL UK ac Iwerddon SIG, Hydref 2021 i Hydref 2022, cadeirydd ISOQOL UK ac Iwerddon SIG, Hydref 2022 i Hydref 2023, cyn-gadeirydd ISOQOL UK ac Iwerddon SIG, Hydref 2023 i Hydref 2024
Grŵp Strategaeth Gweithgor Gweithgor Partneriaeth Ymchwil Methodoleg Treialon MRC-NIHR, Mai 2021 ymlaen
Cydlynydd Rhwydwaith PROMs Cenedlaethol, Medi 2023 ymlaen
NIHR-Versus Arthritis Cydweithio Ressearch Trosiadol Cyhyrysgerbydol (arweinydd academaidd Caerdydd), Mai 2024 ymlaen
Safleoedd academaidd blaenorol
Proffil Gyrfa
2009 - 2014: Cynorthwy-ydd Ymchwil mewn Ystadegau, Uned Treialon De Ddwyrain Cymru a'r Ysgol Deintyddiaeth, Prifysgol Caerdydd
2014 - 2019: Cydymaith Ymchwil mewn Ystadegau, Canolfan Ymchwil Treialon a Chanolfan Triniaeth a Gwerthuso Arthritis Arbrofol Rhanbarthol Caerdydd
2019 - 2024: Ymchwil Iechyd a Gofal Cymru Cymrawd Doethurol NIHR, Canolfan Ymchwil Treialon
2024 - presennol: Cymrawd Ymchwil mewn Ystadegau, Canolfan Ymchwil Treialon Ymchwil
Pwyllgorau ac adolygu
Cynllun Datblygu Adolygydd NIHR
BMJ Agored
PLOSONE
Seminarau mewn Arthritis a Rhewmatiaeth
SAGE Agored
BMC Gwybodeg Meddygol a Gwneud Penderfyniadau
Ymchwil Ansawdd Bywyd
Profedigaeth
F1000
BMC Iechyd ac Ansawdd Canlyniadau Bywyd
Meysydd goruchwyliaeth
Goruchwyliaeth gyfredol
Christian Lambert
Myfyriwr ymchwil
Contact Details
PicklesTE@caerdydd.ac.uk
+44 29206 87259
Neuadd Meirionnydd, Ystafell Ystafell 510, 5ed llawr, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4YS
+44 29206 87259
Neuadd Meirionnydd, Ystafell Ystafell 510, 5ed llawr, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4YS
Themâu ymchwil
Arbenigeddau
- Ystadegau cymhwysol
- Profi, asesu a seicometrigau
- Treialon Clinigol
- Mesurau canlyniadau
- Rhiwmatoleg ac arthritis