Dr Polina Prokopovich

(hi/ei)

2026

• Gambrill, B. , Yang, L. and Prokopovich, P. 2026. Osteoinductive chemically crosslinked hydrogel enables hydroxyapatite formation, enhanced by release of dexamethasone, strontium, and zinc, and exhibits antimicrobial properties. RSC Advances 16 (21), pp.18666-18678. (10.1039/d5ra09258b)
• Duc, D. et al. 2026. Emerging biomimetic biopolymer-based composites: advancing accessible and sustainable neural disease models and therapeutics. Frontiers in Bioengineering and Biotechnology 13 1720254. (10.3389/fbioe.2025.1720254)

2025

• Perni, S. , Subburaman, S. and Prokopovich, P. 2025. Early cost-effectiveness analysis of intra-articular delivery of a PBAE-DEX conjugate for osteoarthritis in a UK population. Clinical Drug Investigation (10.1007/s40261-025-01446-7)
• Gambrill, B. et al. 2025. A novel multilayer antimicrobial urinary catheter material with antimicrobial properties. Materials Advances 6 , pp.1020-1030. (10.1039/d4ma01045k)

2024

• Pavanello, L. et al., 2024. Physicochemical and biological properties of dental materials and formulations with silica nanoparticles: A narrative review. Dental Materials 40 (11), pp.1729-1741. (10.1016/j.dental.2024.07.028)
• Gambrill, B. et al. 2024. Materials-based incidence of urinary catheter associated urinary tract infections and the causative micro-organisms: systematic review and meta-analysis. BMC Urology 24 (1) 186. (10.1186/s12894-024-01565-x)
• Saeedi, T. and Prokopovich, P. 2024. Screening of poly-beta amino ester coated emulsion of ketorolac for cartilage delivery †. Journal of Materials Chemistry B: Materials for biology and medicine 12 (24), pp.5930-5939. (10.1039/d4tb00313f)
• Perni, S. and Prokopovich, P. 2024. Risk equations for prosthetic joint infections (PJIs) in UK: a retrospective study using the Clinical Practice Research Datalink (CPRD) AURUM and GOLD databases. BMJ Open 14 (5) e082501. (10.1136/bmjopen-2023-082501)
• Alghamdi, R. , Pertusati, F. and Prokopovich, P. 2024. Poly-beta-amino-ester licofelone conjugates development for osteoarthritis treatment †. RSC Advances 14 (1), pp.15-28. (10.1039/d3ra04967a)

2023

• Li, Z. et al., 2023. Low‐field actuating magnetic elastomer membranes characterized using fibre‐optic interferometry. Advanced Functional Materials 33 (50) 2301857. (10.1002/adfm.202301857)
• Yang, L. et al. 2023. Nanocomposite orthopaedic bone cement combining long-acting dual antimicrobial drugs. Biomaterials Advances 153 213538. (10.1016/j.bioadv.2023.213538)
• Larissa, P. et al., 2023. Development, characterization and antimicrobial activity of multilayer silica nanoparticles with chlorhexidine incorporated into dental composites. Dental Materials 39 (5), pp.469-477. (10.1016/j.dental.2023.03.005)
• Perni, S. , Bojan, B. and Prokopovich, P. 2023. A retrospective study of risk factors, causative micro-organisms and healthcare resources consumption associated with prosthetic joint infections (PJI) using the Clinical Practice Research Datalink (CPRD) Aurum database. PLoS ONE 18 (3) e0282709. (10.1371/journal.pone.0282709)

2022

• Assylbekova, G. et al., 2022. Sunlight induced synthesis of silver nanoparticles on cellulose for the preparation of antimicrobial textiles. Journal of Photochemistry and Photobiology 11 100134. (10.1016/j.jpap.2022.100134)
• Perni, S. and Prokopovich, P. 2022. Feasibility and application of machine learning enabled fast screening of poly-beta-amino-esters for cartilage therapies. Scientific Reports 12 (1) 14215. (10.1038/s41598-022-18332-3)

2021

• Al Thaher, Y. et al. 2021. PMMA bone cement containing long releasing silica-based chlorhexidine nanocarriers. PLoS ONE 16 (9) e0257947. (10.1371/journal.pone.0257947)
• Saeedi, T. and Prokopovich, P. 2021. Poly beta amino ester coated emulsions of NSAIDs for cartilage treatment. Journal of Materials Chemistry B: Materials for biology and medicine 9 (29), pp.5837-5847. (10.1039/D1TB01024G)
• Perni, S. , Preedy, E. C. and Prokopovich, P. 2021. Amplify antimicrobial photo dynamic therapy efficacy with poly-beta-amino esters (PBAEs). Scientific Reports 11 (1) 7275. (10.1038/s41598-021-86773-3)

2020

• Bojan, B. , Perni, S. and Prokopovich, P. 2020. Systematic review and meta-analysis of tobacco use as a risk factor for prosthetic joint infection after total hip replacement. Arthroplasty Today 6 (4), pp.959-971. (10.1016/j.artd.2020.07.011)
• Saeedi, T. , Alotaibi, H. F. and Prokopovich, P. 2020. Polymer colloids as drug delivery systems for the treatment of arthritis. Advances in Colloid and Interface Science 285 102273. (10.1016/j.cis.2020.102273)
• Perni, S. and Prokopovich, P. 2020. Rheometer enabled study of cartilage frequency-dependent properties. Scientific Reports 10 (1) 20696. (10.1038/s41598-020-77758-9)
• Perni, S. et al. 2020. Long acting anti-infection constructs on titanium. Journal of Controlled Release 326 , pp.91-105. (10.1016/j.jconrel.2020.06.013)
• Perni, S. and Prokopovich, P. 2020. Optimisation and feature selection of poly-beta-amino-ester as a drug delivery system for cartilage. Journal of Materials Chemistry. B 8 (23), pp.5096-5108. (10.1039/C9TB02778E)

2019

• Alotaibi, H. F. , Perni, S. and Prokopovich, P. 2019. Nanoparticle-based model of anti-inflammatory drug releasing LbL coatings for uncemented prosthesis aseptic loosening prevention. International Journal of Nanomedicine 2019 (14), pp.7309. (10.2147/IJN.S217112)
• Perni, S. et al. 2019. Prolonged antimicrobial activity of PMMA bone cement with embedded gentamicin-releasing silica nanocarriers. ACS Applied Bio Materials 2 (5), pp.1850-1861. (10.1021/acsabm.8b00752)
• Rivera, M. et al., 2019. Anti-inflammatory drug-eluting implant model system to prevent wear particles induced periprosthetic osteolysis. International Journal of Nanomedicine 14 , pp.1069-1084. (10.2147/IJN.S188193)

2018

• Al Thaher, Y. et al. 2018. LbL-assembled gentamicin delivery system for PMMA bone cements to prolong antimicrobial activity. PLoS ONE 13 (12) e0207753. (10.1371/journal.pone.0207753)
• Perni, S. et al. 2018. Cobalt and Titanium nanoparticles influence on human osteoblast mitochondrial activity and biophysical properties of their cytoskeleton. Journal of Colloid and Interface Science 531 , pp.410-420. (10.1016/j.jcis.2018.07.028)
• Al Thaher, Y. et al. 2018. Role of poly-beta-amino-esters hydrolysis and electrostatic attraction in Gentamicin release from Layer-by-Layer coatings. Journal of Colloid and Interface Science 526 , pp.35-42. (10.1016/j.jcis.2018.04.042)
• Alotaibi, H. F. et al., 2018. Role of processing parameters on surface and wetting properties controlling the behaviour of layer-by-layer coated nanoparticles. Current Opinion in Colloid and Interface Science 36 , pp.130-142. (10.1016/j.cocis.2018.02.008)
• Perni, S. , Martini-Gilching, K. and Prokopovich, P. 2018. Controlling release kinetics of gentamicin from silica nano-carriers. Colloids and Surfaces A: Physicochemical and Engineering Aspects 541 , pp.212-221. (10.1016/j.colsurfa.2017.04.063)

2017

• Abdurazova, P. et al., 2017. Preparation of photochemical coatings of metal films (copper, silver and gold) on dielectric surfaces and studying their antimicrobial properties. Colloids and Surfaces A: Physicochemical and Engineering Aspects 532 , pp.63-69. (10.1016/j.colsurfa.2017.06.070)
• Al Thaher, Y. , Perni, S. and Prokopovich, P. 2017. Nano-carrier based drug delivery systems for sustained antimicrobial agent release from orthopaedic cementous material. Advances in Colloid and Interface Science 249 , pp.234-247. (10.1016/j.cis.2017.04.017)
• Preedy, E. C. , Perni, S. and Prokopovich, P. 2017. Cobalt and titanium nanoparticles influence on mesenchymal stem cell elasticity and turgidity. Colloids and Surfaces B: Biointerfaces 157 , pp.146-156. (10.1016/j.colsurfb.2017.05.019)
• Sataev, M. S. et al., 2017. A low-temperature gold coating of the dielectric surfaces employing phosphine gas as a reducing agent. Colloids and Surfaces A: Physicochemical and Engineering Aspects 521 , pp.86-91. (10.1016/j.colsurfa.2016.11.029)
• Perni, S. and Prokopovich, P. 2017. Poly-beta-amino-esters nano-vehicles based drug delivery system for cartilage. Nanomedicine: Nanotechnology, Biology and Medicine 13 (2), pp.539-548. (10.1016/j.nano.2016.10.001)

2016

• Perni, S. et al. 2016. Lethal photosensitisation of bacteria using Silica-TBO nanoconjugates. Colloids and Surfaces A: Physicochemical and Engineering Aspects 510 , pp.293-299. (10.1016/j.colsurfa.2016.06.022)
• Giacomo, T. , Perni, S. and Prokopovich, P. 2016. An injectable hydrogel as bone graft material with added antimicrobial properties. Tissue Engineering: Parts A, B, and C 22 (11-12), pp.862-872. (10.1089/ten.tea.2016.0014)
• Preedy, E. C. , Perni, S. and Prokopovich, P. 2016. Nanomechanical and surface properties of rMSCs post exposure to CAP treated UHMWPE wear particles. Nanomedicine: Nanotechnology, Biology and Medicine 12 (3), pp.723-734. (10.1016/j.nano.2015.10.006)
• Perni, S. et al. 2016. Influence of csgD and ompR on nanomechanics, adhesion forces and curli properties of E. coli. Langmuir 32 (31), pp.7965-7974. (10.1021/acs.langmuir.6b02342)

2015

• Perni, S. et al. 2015. Antimicrobial activity of bone cements embedded with organic nanoparticles. International Journal of Nanomedicine 10 , pp.6317-6329. (10.2147/IJN.S86440)
• Preedy, E. C. , Perni, S. and Prokopovich, P. 2015. Cobalt, titanium and PMMA bone cement debris influence on mouse osteoblast cell elasticity, spring constant and calcium production activity. RSC Advances 5 , pp.83885-83898. (10.1039/C5RA15390E)
• Gustaite, S. et al., 2015. Characterization of cellulose based sponges for wound dressings. Colloids and Surfaces A: Physicochemical and Engineering Aspects 480 , pp.336-342. (10.1016/j.colsurfa.2014.08.022)
• Sataev, M. S. et al., 2015. A galvanic-chemical method for preparing diamond containing coatings. Colloids and Surfaces A: Physicochemical and Engineering Aspects 480 , pp.384-389. (10.1016/j.colsurfa.2014.09.014)
• González-Sánchez, M. I. et al., 2015. Silver nanoparticle based antibacterial methacrylate hydrogels potential for bone graft applications. Materials Science and Engineering C 50 , pp.332-340. (10.1016/j.msec.2015.02.002)
• Perni, S. and Prokopovich, P. 2015. Multi-asperity elliptical JKR model for adhesion of a surface with non-axially symmetric asperities. Tribology International 88 , pp.107-114. (10.1016/j.triboint.2015.03.001)
• Prokopovich, P. et al. 2015. Potent antimicrobial activity of bone cement encapsulating silver nanoparticles capped with oleic acid. Journal of Biomedical Materials Research: Part B - Applied Biomaterials 103 (2), pp.273-281. (10.1002/jbm.b.33196)

2014

• Perni, S. , Hakala, V. and Prokopovich, P. 2014. Biogenic synthesis of antimicrobial silver nanoparticles capped with L-cysteine. Colloids and Surfaces A: Physicochemical and Engineering Aspects 460 , pp.219-224. (10.1016/j.colsurfa.2013.09.034)
• Preedy, E. C. et al. 2014. Adhesive forces and surface properties of cold gas plasma treated UHMWPE. Colloids and Surfaces A: Physicochemical and Engineering Aspects 460 , pp.83-89. (10.1016/j.colsurfa.2014.03.052)
• Perni, S. and Prokopovich, P. 2014. Continuous release of gentamicin from gold nanocarrier. RSC Advances 4 (94), pp.51904-51910. (10.1039/C4RA10023A)
• Ramadan, Y. et al., 2014. Obtaining new composite biomaterials by means of mineralization of methacrylate hydrogels using the reaction-diffusion method. Materials Science and Engineering C 42 , pp.696-704. (10.1016/j.msec.2014.06.017)
• Preedy, E. C. et al. 2014. Surface roughness mediated adhesion forces between borosilicate glass and gram-positive bacteria. Langmuir 30 (31), pp.9466-9476. (10.1021/la501711t)
• Omar, F. et al. 2014. Development and experimental validation of an analytical model to predict the demoulding force in hot embossing. Journal of Micromechanics and Microengineering 24 (5), pp.-. 055007. (10.1088/0960-1317/24/5/055007)
• Pandiyaraj, K. N. et al., 2014. Influence of operating parameters on surface properties of RF glow discharge oxygen plasma treated TiO2/PET film for biomedical application. Materials Science and Engineering C 36 , pp.309-319. (10.1016/j.msec.2013.12.018)
• Sataev, M. S. et al., 2014. Novel process for coating textile materials with silver to prepare antimicrobial fabrics. Colloids and Surfaces A: Physicochemical and Engineering Aspects 442 , pp.146-151. (10.1016/j.colsurfa.2013.02.018)
• Perni, S. , Preedy, E. C. and Prokopovich, P. 2014. Success and failure of colloidal approaches in adhesion of microorganisms to surfaces. Advances in Colloid and Interface Science 206 , pp.265-274. (10.1016/j.cis.2013.11.008)
• Prokopovich, P. 2014. Interactions between mammalian cells and nano- or micro-sized wear particles: Physico-chemical views against biological approaches. Advances in Colloid and Interface Science 213 , pp.36-47. (10.1016/j.cis.2014.09.001)

2013

• Khan, I. M. et al. 2013. In vitro growth factor-induced bio engineering of mature articular cartilage. Biomaterials 34 (5), pp.1478-1487. (10.1016/j.biomaterials.2012.09.076)
• Omar, F. et al. 2013. Demoulding forces in hot embossing: Model development and validation. Presented at: 8th International Conference on MicroManufacturing (ICOMM2013) Victoria, Canada 25-28 March 2013. Proceedings of the 8th International Conference on MicroManufacturing (ICOMM2013). , pp.642-649.
• Perni, S. and Prokopovich, P. 2013. Micropatterning with conical features can control bacterial adhesion on silicone. Soft Matter 9 (6), pp.1844-1851. (10.1039/c2sm26828k)
• Prokopovich, P. et al. 2013. A novel bone cement impregnated with silver-tiopronin nanoparticles: its antimicrobial, cytotoxic, and mechanical properties. International Journal of Nanomedicine 8 (1), pp.2227-2237. (10.2147/IJN.S42822)
• Prokopovich, P. and Perni, S. 2013. Contact interactions of aorta against PVC catheters. Tribology International 66 , pp.157-164. (10.1016/j.triboint.2013.03.009)

2012

• Noimark, S. et al., 2012. Incorporation of methylene blue and nanogold into polyvinyl chloride catheters; a new approach for light-activated disinfection of surfaces. Journal of Materials Chemistry 22 (30), pp.15388-15396. (10.1039/C2JM31987J)
• Perni, S. , Kong, M. G. and Prokopovich, P. 2012. Cold atmospheric pressure gas plasma enhances the wear performance of ultra-high molecular weight polyethylene. Acta Biomaterialia 8 (3), pp.1357-1365. (10.1016/j.actbio.2011.12.007)
• Prokopovich, P. 2012. A dimensionless analysis of the effect of material and surface properties on adhesion. applications to medical device design. In: Starov, V. and Griffiths, P. eds. Progress in Colloid and Polymer Sceinve. Vol. 139, Springer Verlag. , pp.59-65. (10.1007/978-3-642-28974-3_11)
• Vicars, R. et al., 2012. The Effect of Anterior-Posterior Shear on the Wear of Charité TDR. Spine 37 (9), pp.E528-E534. (10.1097/BRS.0b013e31823cbd6e)

2011

• Perni, S. et al., 2011. Antimicrobial Properties of Light-activated Polyurethane Containing Indocyanine Green. Journal of Biomaterials Applications 25 (5), pp.387-400. (10.1177/0885328209352701)
• Perni, S. et al., 2011. Nanoparticles: their potential use in antibacterial photodynamic therapy. Photochemical and Photobiological Sciences 10 (5), pp.712-720. (10.1039/C0PP00360C)
• Prokopovich, P. and Perni, S. 2011. Comparison of JKR- and DMT-based multi-asperity adhesion model: Theory and experiment. Colloids and Surfaces A: Physicochemical and Engineering Aspects 383 (1-3), pp.95-101. (10.1016/j.colsurfa.2011.01.011)
• Prokopovich, P. et al. 2011. Spatial variation of wear on Charité lumbar discs. Acta Biomaterialia 7 (11), pp.3914-3926. (10.1016/j.actbio.2011.06.036)
• Prokopovich, P. and Starov, V. 2011. Adhesion models: From single to multiple asperity contacts. Advances in Colloid and Interface Science 168 (1-2), pp.210-222. (10.1016/j.cis.2011.03.004)

2010

• Prokopovich, P. and Perni, S. 2010. Multiasperity contact adhesion model for universal asperity height and radius of curvature distributions. Langmuir 26 (22), pp.17028-17036. (10.1021/la102208y)
• Perni, S. et al., 2010. Prevention of biofilm accumulation on a light-activated antimicrobial catheter material. Journal of Materials Chemistry 20 (39), pp.8668-8673. (10.1039/C0JM01891K)
• Prokopovich, P. and Perni, S. 2010. Prediction of the frictional behavior of mammalian tissues against biomaterials. Acta Biomaterialia 6 (10), pp.4052-4059. (10.1016/j.actbio.2010.05.007)
• Prokopovich, P. et al. 2010. Frictional Properties of Light-activated Silicone and Polyurethane against blood vessels. Journal of Materials Science: Materials in Medicine 21 (2), pp.815-821. (10.1007/s10856-009-3882-2)
• Prokopovich, P. et al. 2010. Friction in ultra-thin conjunction of valve seals of pressurised metered dose inhalers. Wear 268 (5-6), pp.845-852. (10.1016/j.wear.2009.12.003)
• Prokopovich, P. et al. 2010. Nano- and component level friction of rubber seals in dispensing devices. Presented at: ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference San Diego, CA, USA 30 August-2 September 2009. ASME Power Transmission and Gearing Conference; 3rd International Conference on Micro- and Nanosystems; 11th International Conference on Advanced Vehicle and Tire Technologies. ASME Conference Proceedings Vol. 6. New York: ASME. , pp.339-344. (10.1115/DETC2009-86035)

2009

• Perni, S. et al., 2009. Toluidine blue-containing polymers exhibit potent bactericidal activity when irradiated with red laser light. Journal of Materials Chemistry 19 (18), pp.2715-2723. (10.1039/B820561B)
• Perni, S. et al., 2009. The antimicrobial properties of light-activated polymers containing methylene blue and gold nanoparticles. Biomaterials 30 (1), pp.89-93. (10.1016/j.biomaterials.2008.09.020)
• Piccirillo, C. et al., 2009. Antimicrobial activity of methylene blue and toluidine blue O covalently bound to a modified silicone polymer surface. Journal of Materials Chemistry 19 (34), pp.6167-6171. (10.1039/b905495b)
• Prokopovich, P. and Perni, S. 2009. An investigation of microbial adhesion to natural and synthetic polysaccharide-based films and its relationship with the surface energy components. Journal of Materials Science: Materials in Medicine 20 (1), pp.195-202. (10.1007/s10856-008-3555-6)

2007

• Dmitrieva, I. B. et al., 2007. Investigation of the electrosurface properties of NiO and Fe2O3 in azole solutions. Colloids and Surfaces A: Physicochemical and Engineering Aspects 300 (3), pp.315-320. (10.1016/j.colsurfa.2007.01.046)

2006

• Holdich, R. et al., 2006. Spreading of liquid drops from a liquid source. Colloids and Surfaces A: Physicochemical and Engineering Aspects 282-83 , pp.247-255. (10.1016/j.colsurfa.2005.11.023)
• Prokopovich, P. et al. 2006. Concentration of potassium cations in the permeate solution in the presence of N,N-dimethyl-N-2-propenyl-2-propen-1-aminium chloride homopolymer using dead-end nano-or ultrafiltration. Colloid Journal c/c of Kolloidnyi Zhurnal 68 (2), pp.211-216. (10.1134/S1061933X0602013X)

2005

• Churaev, N. V. et al., 2005. Reversible adsorption inside pores of ultrafiltration membranes. Journal of Colloid and Interface Science 288 (1), pp.205-212. (10.1016/j.jcis.2005.02.072)
• Prokopovich, P. , Starov, V. and Holdich, R. G. 2005. Concentration of inorganic salts in the permeate during nano- or ultrafiltration promoted by water-soluble polyelectrolytes in the feed solution. Industrial & Engineering Chemistry Research 44 (5), pp.1358-1369. (10.1021/ie049696l)

2004

• Dmitrieva, I. B. et al., 2004. Specific adsorption of barbituric acid on ferric(III) and nickel(II) oxides. Colloids and Surfaces A: Physicochemical and Engineering Aspects 239 (1-3), pp.19-24. (10.1016/j.colsurfa.2003.12.033)