![Jack Reddaway](https://profiles-cardiff.imgix.net/attachments/1185?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Trosolwyg
Ar hyn o bryd rwy'n uwch ymchwilydd ôl-ddoethurol yn labordy yr Athro Paul Morgan a Dr Wioleta Zelek, llwybrau therapiwtig newydd ymchwil ar gyfer trin Clefyd Alzheimer.
Mae gen i arbenigedd mewn delweddu cellog trwybwn uchel, ailadeiladu cellog ac asesiad gwybyddol cnofilod yr wyf wedi'i ddefnyddio'n dda trwy gydol fy PhD ac ymchwil ôl-ddoethurol dilynol.
Mae fy niddordebau ymchwil yn canolbwyntio ar y rôl y mae microglia yn ei chwarae wrth addasu swyddogaeth niwronau a gwybyddiaeth. Mae deall y berthynas gymhleth rhwng microglia a niwronau o bwysigrwydd arbennig o ystyried bod rhyngweithiadau camweithredol rhwng microglia-niwronau yn gysylltiedig ag aetioleg llawer o anhwylderau niwroddatblygiadol a niwroddirywiol.
Cyhoeddiad
2023
- Reddaway, J., Richardson, P. E., Bevan, R. J., Stoneman, J. and Palombo, M. 2023. Microglial morphometric analysis: so many options, so little consistency. Frontiers in Neuroinformatics 17, article number: 1211188. (10.3389/fninf.2023.1211188)
2022
- Poppelaars, F., da Costa, M. G., Inkeri Lokki, A., Mallah, K., Nord, D., Reddaway, J. and Schäfer, N. 2022. Early-Career Complementologists (ECCO): past achievements and future directions. Molecular Immunology 151, pp. 158-165. (10.1016/j.molimm.2022.08.012)
- Westacott, L. J. et al. 2022. Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder. Brain, Behavior, and Immunity 99, pp. 70-82. (10.1016/j.bbi.2021.09.005)
- Poppelaars, F., Gaya da Costa, M., Inkeri Lokki, A., Mallah, K., Nord, D., Reddaway, J. and Schäfer, N. 2022. ECCO - A new initiative to support early-career researchers in the complement field. Molecular Immunology 141, pp. 104-107. (10.1016/j.molimm.2021.11.018)
- Reddaway, J. 2022. The role of the complement system in associative learning and risk for schizophrenia. PhD Thesis, Cardiff University.
2020
- Reddaway, J. and Brydges, N. M. 2020. Enduring neuroimmunological consequences of developmental experiences: from vulnerability to resilience. Molecular and Cellular Neuroscience 109, article number: 103567. (10.1016/j.mcn.2020.103567)
- Brydges, N. and Reddaway, J. 2020. Neuroimmunological effects of early life experiences. Brain and Neuroscience Advances 4 (10.1177/2398212820953706)
2018
- Reddaway, J., Doherty, J. L., Lancaster, T., Linden, D., Walters, J. T. and Hall, J. 2018. Genomic and imaging biomarkers in schizophrenia. In: Current Topics in Behavioral Neurosciences. Berlin and Heidelberg: Springer, pp. 325-352., (10.1007/7854_2018_52)
Articles
- Reddaway, J., Richardson, P. E., Bevan, R. J., Stoneman, J. and Palombo, M. 2023. Microglial morphometric analysis: so many options, so little consistency. Frontiers in Neuroinformatics 17, article number: 1211188. (10.3389/fninf.2023.1211188)
- Poppelaars, F., da Costa, M. G., Inkeri Lokki, A., Mallah, K., Nord, D., Reddaway, J. and Schäfer, N. 2022. Early-Career Complementologists (ECCO): past achievements and future directions. Molecular Immunology 151, pp. 158-165. (10.1016/j.molimm.2022.08.012)
- Westacott, L. J. et al. 2022. Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder. Brain, Behavior, and Immunity 99, pp. 70-82. (10.1016/j.bbi.2021.09.005)
- Poppelaars, F., Gaya da Costa, M., Inkeri Lokki, A., Mallah, K., Nord, D., Reddaway, J. and Schäfer, N. 2022. ECCO - A new initiative to support early-career researchers in the complement field. Molecular Immunology 141, pp. 104-107. (10.1016/j.molimm.2021.11.018)
- Reddaway, J. and Brydges, N. M. 2020. Enduring neuroimmunological consequences of developmental experiences: from vulnerability to resilience. Molecular and Cellular Neuroscience 109, article number: 103567. (10.1016/j.mcn.2020.103567)
- Brydges, N. and Reddaway, J. 2020. Neuroimmunological effects of early life experiences. Brain and Neuroscience Advances 4 (10.1177/2398212820953706)
Book sections
- Reddaway, J., Doherty, J. L., Lancaster, T., Linden, D., Walters, J. T. and Hall, J. 2018. Genomic and imaging biomarkers in schizophrenia. In: Current Topics in Behavioral Neurosciences. Berlin and Heidelberg: Springer, pp. 325-352., (10.1007/7854_2018_52)
Thesis
- Reddaway, J. 2022. The role of the complement system in associative learning and risk for schizophrenia. PhD Thesis, Cardiff University.
Bywgraffiad
ADDYSG
Canolfan Hodge ar gyfer Imiwnoleg Niwroseiciatrig, Prifysgol Caerdydd, Caerdydd, UK
PhD (Meddygaeth) 2017 - 2021
Teitl y prosiect: Rôl y system ategu mewn gogwyddo cysylltiol a risg ar gyfer sgitsoffrenia
Univeristy of Bath, Bath, UK
BSc Anrhydedd mewn Biocemeg 2012 – 2016
PROFIAD YMCHWIL
Ysgol Meddygaeth, Prifysgol Caerdydd, Caerdydd, y DU
Uwch gydymaith ymchwil ôl-ddoethurol 2024 – presennol
Prosiect sy'n ymchwilio i ddatblygu a phrofi therapiwteg newydd ar gyfer trin clefyd Alzheimer
Ysgol y Biowyddorau, Prifysgol Caerdydd, Caerdydd, UK
Cydymaith ymchwil ôl-ddoethurol 2021 – 2024
Roedd prosiect sy'n ymchwilio i effaith syndrom Prader-Willi yn gysylltiedig â genyn nad yw'n codio RNA Snord116 dileu ar ddatblygiad niwronau cortigol a hippocampal.
Cychwyn Biotech, Copenhagen Denmarc
Ymchwilydd sy'n ymweld 2022 - 2022
Canolfan Hodge ar gyfer Imiwnoleg Niwroseiciatrig, Prifysgol Caerdydd, Caerdydd, UK
Phd 2017 – 2021
Prosiect sy'n ymchwilio i actifadu imiwnedd yn dilyn adfer neu ddifodiant atgofion ofn cyd-destunol. Datblygu llwyfan newydd i asesu morffoleg microglia >10,000 a rhagweld statws actifadu microglia dywededig gan ddefnyddio dysgu peirianyddol.
Niwrotrauma Trosiadol, Iechyd Plant, Coleg Meddygaeth Prifysgol Arizona, Phoenix, AZ
Myfyriwr Lleoliad Prifysgol Caerfaddon 2014 - 2015
Anrhydeddau a dyfarniadau
Gwobr Teithio 2023, Sefydliad Ymchwil Prader-Willi
Gwobr Teithio 2023, Gwarantwyr yr Ymennydd
Prosiect Grant 2022, Cychwyn Biotech
Gwobr Teithio 2022, Sefydliad Ymchwil Prader-Willi
2022 Grant Prosiect, Sefydliad Ymchwil Prader-Willi
Grant Arloesi Ymchwil Cymru 2021, Llywodraeth Cymru
Gwobr Teithio 2019, Hycult Biotech
Gwobr Teithio 2018, Labordai Oer Spring Harbor