![Jack Reddaway](https://profiles-cardiff.imgix.net/attachments/1185?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Trosolwyg
Ar hyn o bryd rwy'n uwch ymchwilydd ôl-ddoethurol yn labordy yr Athro Paul Morgan a Dr Wioleta Zelek, llwybrau therapiwtig newydd ymchwil ar gyfer trin Clefyd Alzheimer.
Mae gen i arbenigedd mewn delweddu cellog trwybwn uchel, ailadeiladu cellog ac asesiad gwybyddol cnofilod yr wyf wedi'i ddefnyddio'n dda trwy gydol fy PhD ac ymchwil ôl-ddoethurol dilynol.
Mae fy niddordebau ymchwil yn canolbwyntio ar y rôl y mae microglia yn ei chwarae wrth addasu swyddogaeth niwronau a gwybyddiaeth. Mae deall y berthynas gymhleth rhwng microglia a niwronau o bwysigrwydd arbennig o ystyried bod rhyngweithiadau camweithredol rhwng microglia-niwronau yn gysylltiedig ag aetioleg llawer o anhwylderau niwroddatblygiadol a niwroddirywiol.
Cyhoeddiad
2023
- Reddaway, J. et al. 2023. Microglial morphometric analysis: so many options, so little consistency. Frontiers in Neuroinformatics 17 1211188. (10.3389/fninf.2023.1211188)
2022
- Poppelaars, F. et al., 2022. Early-Career Complementologists (ECCO): past achievements and future directions. Molecular Immunology 151 , pp.158-165. (10.1016/j.molimm.2022.08.012)
- Poppelaars, F. et al., 2022. ECCO - A new initiative to support early-career researchers in the complement field. Molecular Immunology 141 , pp.104-107. (10.1016/j.molimm.2021.11.018)
- Westacott, L. J. et al. 2022. Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder. Brain, Behavior, and Immunity 99 , pp.70-82. (10.1016/j.bbi.2021.09.005)
- Reddaway, J. 2022. The role of the complement system in associative learning and risk for schizophrenia. PhD Thesis , Cardiff University.
2020
- Reddaway, J. and Brydges, N. M. 2020. Enduring neuroimmunological consequences of developmental experiences: from vulnerability to resilience. Molecular and Cellular Neuroscience 109 103567. (10.1016/j.mcn.2020.103567)
- Brydges, N. and Reddaway, J. 2020. Neuroimmunological effects of early life experiences. Brain and Neuroscience Advances 4 (10.1177/2398212820953706)
2018
- Reddaway, J. et al. 2018. Genomic and imaging biomarkers in schizophrenia. In: Current Topics in Behavioral Neurosciences. Berlin and Heidelberg: Springer. , pp.325-352. (10.1007/7854_2018_52)
Articles
- Reddaway, J. et al. 2023. Microglial morphometric analysis: so many options, so little consistency. Frontiers in Neuroinformatics 17 1211188. (10.3389/fninf.2023.1211188)
- Poppelaars, F. et al., 2022. Early-Career Complementologists (ECCO): past achievements and future directions. Molecular Immunology 151 , pp.158-165. (10.1016/j.molimm.2022.08.012)
- Poppelaars, F. et al., 2022. ECCO - A new initiative to support early-career researchers in the complement field. Molecular Immunology 141 , pp.104-107. (10.1016/j.molimm.2021.11.018)
- Westacott, L. J. et al. 2022. Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder. Brain, Behavior, and Immunity 99 , pp.70-82. (10.1016/j.bbi.2021.09.005)
- Reddaway, J. and Brydges, N. M. 2020. Enduring neuroimmunological consequences of developmental experiences: from vulnerability to resilience. Molecular and Cellular Neuroscience 109 103567. (10.1016/j.mcn.2020.103567)
- Brydges, N. and Reddaway, J. 2020. Neuroimmunological effects of early life experiences. Brain and Neuroscience Advances 4 (10.1177/2398212820953706)
Book sections
- Reddaway, J. et al. 2018. Genomic and imaging biomarkers in schizophrenia. In: Current Topics in Behavioral Neurosciences. Berlin and Heidelberg: Springer. , pp.325-352. (10.1007/7854_2018_52)
Thesis
- Reddaway, J. 2022. The role of the complement system in associative learning and risk for schizophrenia. PhD Thesis , Cardiff University.
Bywgraffiad
ADDYSG
Canolfan Hodge ar gyfer Imiwnoleg Niwroseiciatrig, Prifysgol Caerdydd, Caerdydd, UK
PhD (Meddygaeth) 2017 - 2021
Teitl y prosiect: Rôl y system ategu mewn gogwyddo cysylltiol a risg ar gyfer sgitsoffrenia
Univeristy of Bath, Bath, UK
BSc Anrhydedd mewn Biocemeg 2012 – 2016
PROFIAD YMCHWIL
Ysgol Meddygaeth, Prifysgol Caerdydd, Caerdydd, y DU
Uwch gydymaith ymchwil ôl-ddoethurol 2024 – presennol
Prosiect sy'n ymchwilio i ddatblygu a phrofi therapiwteg newydd ar gyfer trin clefyd Alzheimer
Ysgol y Biowyddorau, Prifysgol Caerdydd, Caerdydd, UK
Cydymaith ymchwil ôl-ddoethurol 2021 – 2024
Roedd prosiect sy'n ymchwilio i effaith syndrom Prader-Willi yn gysylltiedig â genyn nad yw'n codio RNA Snord116 dileu ar ddatblygiad niwronau cortigol a hippocampal.
Cychwyn Biotech, Copenhagen Denmarc
Ymchwilydd sy'n ymweld 2022 - 2022
Canolfan Hodge ar gyfer Imiwnoleg Niwroseiciatrig, Prifysgol Caerdydd, Caerdydd, UK
Phd 2017 – 2021
Prosiect sy'n ymchwilio i actifadu imiwnedd yn dilyn adfer neu ddifodiant atgofion ofn cyd-destunol. Datblygu llwyfan newydd i asesu morffoleg microglia >10,000 a rhagweld statws actifadu microglia dywededig gan ddefnyddio dysgu peirianyddol.
Niwrotrauma Trosiadol, Iechyd Plant, Coleg Meddygaeth Prifysgol Arizona, Phoenix, AZ
Myfyriwr Lleoliad Prifysgol Caerfaddon 2014 - 2015
Anrhydeddau a dyfarniadau
Gwobr Teithio 2023, Sefydliad Ymchwil Prader-Willi
Gwobr Teithio 2023, Gwarantwyr yr Ymennydd
Prosiect Grant 2022, Cychwyn Biotech
Gwobr Teithio 2022, Sefydliad Ymchwil Prader-Willi
2022 Grant Prosiect, Sefydliad Ymchwil Prader-Willi
Grant Arloesi Ymchwil Cymru 2021, Llywodraeth Cymru
Gwobr Teithio 2019, Hycult Biotech
Gwobr Teithio 2018, Labordai Oer Spring Harbor