![Faizan Sadiq BSc (Hons) MSc PhD](https://profiles-cardiff.imgix.net/attachments/6232?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Dr Faizan Sadiq
(e/fe)
BSc (Hons) MSc PhD
Darlithydd (Athro Cynorthwyol) - Bioffilmiau Microbaidd
- Ar gael fel goruchwyliwr ôl-raddedig
Trosolwyg
Rwy'n ficrobiolegydd sydd â diddordeb brwd mewn archwilio ecoleg bacteriol a rhyngweithiadau rhwng rhywogaethau mewn bioffilmiau microbaidd ar draws amgylcheddau clinigol a diwydiannol amrywiol. Yn gynyddol, mae'n dod yn amlwg bod mwyafrif y rhywogaethau bacteriol ym myd natur yn bodoli o fewn bioffilmiau rhywogaethau cymysg, wedi'u siapio gan sbectrwm o ryngweithio cymdeithasol yn amrywio o gydweithrediad i antagoniaeth, nid yn unig ymhlith bacteria ond hefyd gydag aelodau o deyrnasoedd eraill. Credaf fod dealltwriaeth ddyfnach o ffisioleg bacteriol, ecoleg, nodweddion metabolig, a nodweddion esblygiadol yn gofyn am ystyriaeth gyfannol o'u cyd-destun biolegol.
Mae gen i ddiddordeb mewn datrys mynychder a mecanweithiau sy'n sail i ryngweithiadau cymdeithasol amrywiol o fewn bioffilmiau sy'n gysylltiedig â llawer o leoliadau naturiol, gan gynnwys clwyfau croen cronig, mewnblaniadau, y ceudod geg, a heintiau rheolaidd. Yn benodol, fy nod yw egluro sut mae'r rhyngweithiadau hyn yn dylanwadu ar ymatebion bacteriol i wrthfiotigau neu gyfansoddion eraill, megis polymerau naturiol newydd, a sut maent yn effeithio ar esblygiad a lledaeniad ymwrthedd a ffyrnigrwydd. Fy nod yw ymchwilio i fecanweithiau a gyrwyr (cemegol a biolegol) cydfodoli rhywogaethau o fewn y cilfach bioffilm, gan gynnwys dibyniaethau metabolaidd a'r angen am agregiad corfforol ymhlith micro-organebau amrywiol. Fy nod yw datblygu strategaethau arloesol gyda'r nod o darfu ar bioffilmiau neu atal eu ffurfio trwy dargedu rhywogaethau cerrig allweddol a modiwleiddio rhyngweithio cymdeithasol o fewn y cymunedau microbaidd cymhleth hyn. Mae gennyf ddiddordeb hefyd mewn datblygu a defnyddio probiotegau penodol i dargedu a rheoli cymunedau microbaidd annymunol mewn lleoliadau clinigol a diwydiannol.
Cyhoeddiad
2025
- Jia, R., Zhao, J., Tian, S., Sadiq, F. A., Lu, S., Gao, P. and Zhang, G. 2025. Enzymatic degradation of Ochratoxin A by a novel bacterium, Microbacterium esteraromaticum ASAG1016. International Journal of Food Microbiology 434, article number: 111155. (10.1016/j.ijfoodmicro.2025.111155)
2024
- Mao, K. et al. 2024. Integrated network pharmacology and transcriptomic approach reveal the role of equol in reducing colorectal cancer via regulating multiple cell cycle genes in HCT116 cells.. International Journal of Biological Macromolecules 282(Pt 2), article number: 136832. (10.1016/j.ijbiomac.2024.136832)
- Yu, Y. et al. 2024. Comparison of the effects of three sourdough postbiotics on high-fat diet-induced intestinal damage. Food and Function 15(18), pp. 9053-9069. (10.1039/D4FO02948H)
- Cheng, T. et al. 2024. The complex world of kefir: Structural insights and symbiotic relationships. Comprehensive Reviews in Food Science and Food Safety 23(4), article number: e13364. (10.1111/1541-4337.13364)
- Gao, J., Xu, C., Tian, G., Ji, Y. H., Sadiq, F. A., Wang, K. and Sang, Y. 2024. A study revealing mechanisms behind the stone cell of Yali pear degradation by mixed‐culture fermentation of lactic acid bacteria and yeast. eFood 5(3), article number: e153. (10.1002/efd2.153)
- Sadiq, F. A., De Reu, K., Yang, N., Burmølle, M. and Heyndrickx, M. 2024. Interspecies interactions in dairy biofilms drive community structure and response against cleaning and disinfection. Biofilm 7, article number: 100195. (10.1016/j.bioflm.2024.100195)
- He, X., Yu, Y., Kemperman, R., Jimenez, L., Sadiq, F. A. and Zhang, G. 2024. Comparative genomics reveals genetic diversity and variation in metabolic traits in Fructilactobacillus sanfranciscensis strains. Microorganisms 12(5), article number: 845. (10.3390/microorganisms12050845)
- Fu, M., Gao, J., Mao, K., Sun, J., Sadiq, F. A. and Sang, Y. 2024. Interaction mechanism between surface layer protein and yeast mannan: Insights from multi-spectroscopic and molecular dynamics simulation analyses. Food Chemistry 433, article number: 137352. (10.1016/j.foodchem.2023.137352)
2023
- Sadiq, F. . A., De Reu, K., Steenackers, H., Van de Walle, A., Burmølle, M. and Heyndrickx, M. 2023. Dynamic social interactions and keystone species shape the diversity and stability of mixed-species biofilms – an example from dairy isolates. ISME Communications 3(1), article number: 118. (10.1038/s43705-023-00328-3)
- Yongabi, D. et al. 2023. QCM‐D Viscoelastic and Adhesion Monitoring Facilitate Label‐Free and Strain‐Selective Bacterial Discrimination. physica status solidi (a) – applications and materials science 220(22), article number: 2300310. (10.1002/pssa.202300310)
- Hongchao, W. et al. 2023. Weight loss promotion in individuals with obesity through gut microbiota alterations with a multiphase modified ketogenic diet. Nutrients 15(19), article number: 4163. (10.3390/nu15194163)
- Liu, Y., Danial, M., Liu, L., Sadiq, F. A., Wei, X. and Zhang, G. 2023. Effects of co-fermentation of Lactiplantibacillus plantarum and Saccharomyces cerevisiae on digestive and quality properties of steamed bread. Foods 12, article number: 3333. (10.3390/foods12183333)
- Wang, H. et al. 2023. Modulating the human gut microbiota through hypocaloric balanced diets: An effective approach for managing obesity. Nutrients 15(14), article number: 3101. (10.3390/nu15143101)
- Jia, R. et al. 2023. Tuning Thermostability and Catalytic Efficiency of Aflatoxin-Degrading Enzyme by Error-prone PCR. Applied Microbiology and Biotechnology 107, pp. 4833-4843. (10.1007/s00253-023-12610-4)
- Sadiq, F. A., De Reu, K., Burmølle, M., Maes, S. and Heyndrickx, M. 2023. Synergistic interactions in multispecies biofilm combinations of bacterial isolates recovered from diverse food processing industries. Frontiers in Microbiology 14, article number: 1159434. (10.3389/fmicb.2023.1159434)
2022
- Yuehong, J. et al. 2022. Pear pomace soluble dietary fiber ameliorates the negative effects of high-fat diet in mice by regulating the gut microbiota and associated metabolites. Frontiers in Nutrition 9, article number: 1025511. (10.3389/fnut.2022.1025511)
- Liu, X. et al. 2022. Application of stable isotopic and mineral elemental fingerprints in identifying the geographical origin of concentrated apple juice in China. Food Chemistry 391, article number: 133269. (10.1016/j.foodchem.2022.133269)
- Gao, J., Sadiq, F. A., Zheng, Y., Zhao, J., He, G. and Sang, Y. 2022. Biofilm-based delivery approaches and specific enrichment strategies of probiotics in the human gut. Gut Microbes 14(1), article number: 2126274. (10.1080/19490976.2022.2126274)
- Yuan, L., Wang, H., Liu, W., Sadiq, F. A. and Zhao, Y. 2022. Editorial: Multi-species biofilms in the food industry. Frontiers in Microbiology 13, article number: 1023428. (10.3389/fmicb.2022.1023428)
- Gao, J. et al. 2022. Immunoregulatory effect of Lactobacillus paracasei VL8 exopolysaccharide on RAW264.7 cells by NF-κB and MAPK pathways. Journal of Functional Foods 95, article number: 105166. (10.1016/j.jff.2022.105166)
- Tongxin, Z. et al. 2022. Novel antioxidant peptides from protein hydrolysates of scallop (Argopecten irradians) mantle using enzymatic and microbial methods: Preparation, purification, identification and characterization. LWT - Food Science and Technology 164, article number: 113636. (10.1016/j.lwt.2022.113636)
- Liu, X. et al. 2022. Origin verification of Chinese concentrated apple juice using stable isotopic and mineral elemental fingerprints coupled with chemometrics. Journal of Food Composition and Analysis 109, article number: 104424. (10.1016/j.jfca.2022.104424)
- Sadiq, F. A. et al. 2022. Trans-kingdom interactions in mixed biofilm communities. FEMS Microbiology Reviews 46(5), article number: fuac024. (10.1093/femsre/fuac024)
- Qi, Q. et al. 2022. Preparation and antioxidant properties of germinated soybean protein hydrolysates. Frontiers in Nutrition 9, article number: 866239. (10.3389/fnut.2022.866239)
- Fu, M., Mao, K., Gao, J., Wang, X., Sadiq, F. A., Li, J. and Sang, Y. 2022. Characteristics of surface layer protein from Lactobacillus kefiri HBA20 and the role in mediating interactions with Saccharomyces cerevisiae Y8. International Journal of Biological Macromolecules 201, pp. 254-261. (10.1016/j.ijbiomac.2021.12.049)
- Mao, K. et al. 2022. Bifidobacterium animalis subsp. lactis BB-12 has effect against obesity by regulating gut microbiota in two phases in human microbiota-associated rats. Frontiers in Nutrition 8, article number: 811619. (10.3389/fnut.2021.811619)
2021
- Lei, Y., Sadiq, F. A., Wang, N., Yang, Z. and He, G. 2021. Recent advances in understanding the control of disinfectant-resistant biofilms by hurdle technology in the food industry. Critical Reviews in Food Science and Nutrition 61(22), pp. 3876-3891. (10.1080/10408398.2020.1809345)
- Guohua, Z., Qi, Q., Sadiq, F. A., Wang, W., He, X. and Wei, W. 2021. Proteomic analysis explores interactions between Lactiplantibacillus plantarum and Saccharomyces cerevisiae during sourdough fermentation. Microorganisms 9(11), article number: 2353. (10.3390/microorganisms9112353)
- Dan, W., Emmanuel, K. and Sadiq, F. A. 2021. New trends in photodynamic inactivation (PDI) combating biofilms in the food industry—A review. Foods 10(11), article number: 2587. (10.3390/foods10112587)
- Sadiq, F. A., Lu, W., Wei, C., Jianxin, Z. and Zhang, H. 2021. Transcriptional changes in Bifidobacterium bifidum involved in synergistic multispecies biofilms. Microbial Ecology 84, pp. 922-934. (10.1007/s00248-021-01904-7)
- Sadiq, F. A. and Flint, S. 2021. Dairy strains of Anoxybacillus flavithermus inhibit lipase production by Geobacillus stearothermophilus. International Dairy Journal 119, article number: 104996. (10.1016/j.idairyj.2021.104996)
- Gao, J., Xiyu, L., Zhang, G., Sadiq, F. A., Simal-Gandara, J., Xiao, J. and Sang, Y. 2021. Probiotics in the dairy industry—Advances and opportunities. Comprehensive Reviews in Food Science and Food Safety 20(4), pp. 3937-3982. (10.1111/1541-4337.12755)
- Sadiq, F. A., Lu, W., Heyndrickx, M., Flint, S., Wei, C., Jianxin, Z. and Zhang, H. 2021. Synergistic interactions prevail in multispecies biofilms formed by the human gut microbiota on mucin. FEMS Microbiology Ecology 97(8), article number: fiab096. (10.1093/femsec/fiab096)
- Pei, Z. et al. 2021. Comprehensive scanning of prophages in Lactobacillus: Distribution, diversity, antibiotic resistance genes, and linkages with CRISPR-Cas systems. mSystems 6(3), article number: 01211-20. (10.1128/msystems.01211-20)
- Sadiq, F. A., Mette, B., Heyndrickx, M., Flint, S., Lu, W. and Chen, W. 2021. Community-wide changes reflecting bacterial interspecific interactions in multispecies biofilms. Critical Reviews in Microbiology 47(3), pp. 338-358. (10.1080/1040841x.2021.1887079)
- Liu, Z. et al. 2021. Transcriptome analysis reveals the genes involved in Bifidobacterium Longum FGSZY16M3 biofilm formation. Microorganisms 9(2), article number: 385. (10.3390/microorganisms9020385)
- Sun, S. et al. 2021. HPP and SGQR peptides from silkworm pupae protein hydrolysates regulated biosynthesis of cholesterol in HepG2 cell line. Journal of Functional Foods 77, article number: 104328. (10.1016/j.jff.2020.104328)
- Jia, R., Sadiq, F. A., Liu, W., Cao, L. and Shen, Z. 2021. Protective effects of Bacillus subtilis ASAG 216 on growth performance, antioxidant capacity, gut microbiota and tissues residues of weaned piglets fed deoxynivalenol contaminated diets. Food and Chemical Toxicology 148, article number: 111962. (10.1016/j.fct.2020.111962)
- Sadiq, F. A. 2021. Is it time for microbiome-based therapies in viral infections?. Virus Research 291, article number: 198203. (10.1016/j.virusres.2020.198203)
2020
- Yu, Z., Wang, J., Zhu, Z., Li, X., Sun, S., Wang, W. and Sadiq, A. F. 2020. Identification and characterization of two novel antioxidant peptides from silkworm pupae protein hydrolysates. European Food Research and Technology 247, pp. 343–352. (10.1007/s00217-020-03626-5)
- Pei, Z. et al. 2020. Identification, characterization, and phylogenetic analysis of eight new inducible prophages in Lactobacillus. Virus Research 286, article number: 198003. (10.1016/j.virusres.2020.198003)
- Yi, Z., Sadiq, F. A., Wang, H., Zhao, J., Zhang, H., Lu, W. and Chen, W. 2020. Establishment and evaluation of a method for efficient screening of Clostridium butyricum. Folia Microbiologica 65, pp. 917-924. (10.1007/s12223-020-00803-7)
- Guo, M. et al. 2020. Effects of noni fruit and fermented noni juice against acute alcohol induced liver injury in mice. Journal of Functional Foods 70, article number: 103995. (10.1016/j.jff.2020.103995)
- Du, X. et al. 2020. Two‐dimensional liquid chromatography analysis of all‐trans‐, 9‐cis‐, and 13‐cis‐astaxanthin in raw extracts from Phaffia rhodozyma. Journal of Separation Science 43(16), pp. 3206-3215. (10.1002/jssc.202000257)
- Lei, Y., Wang, N., Sadiq, F. A. and Guoqing, H. 2020. Interspecies interactions in dual-species biofilms formed by psychrotrophic bacteria and the tolerance of sessile communities to disinfectants. Journal of Food Protection 83(6), pp. 951-958. (10.4315/0362-028x.jfp-19-396)
- Lei, Y., Wang, N., Sadiq, F. A. and Guoqing, H. 2020. RNA sequencing reveals the involvement of quorum sensing in dairy spoilage caused by psychrotrophic bacteria. LWT - Food Science and Technology 127, article number: 109384. (10.1016/j.lwt.2020.109384)
- Wang, N., Wang, W., Sadiq, F. A., Wang, S., Caiqin, L. and Jianchang, J. 2020. Involvement of Nrf2 and Keap1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent peptides from soft-shelled turtle. Process Biochemistry 92, pp. 174-181. (10.1016/j.procbio.2019.12.022)
- Yang, H., Sadiq, F. A., Liu, T., Zhang, G. and He, G. 2020. Use of physiological and transcriptome analysis to infer the interactions between Saccharomyces cerevisiae and Lactobacillus sanfranciscensis isolated from Chinese traditional sourdoughs. LWT - Food Science and Technology 126, article number: 109268. (10.1016/j.lwt.2020.109268)
- Wang, N., Sadiq, F. A., Li, S., He, G. and Yuan, L. 2020. Tandem mass tag-based quantitative proteomics reveals the regulators in biofilm formation and biofilm control of Bacillus licheniformis. Food Control 110, article number: 107029. (10.1016/j.foodcont.2019.107029)
- Flint, S. et al. 2020. Bacterial fouling in dairy processing. International Dairy Journal 101, article number: 104593. (10.1016/j.idairyj.2019.104593)
- Sadiq, F. A., Yan, B., Zhao, J., Zhang, H. and Chen, W. 2020. Untargeted metabolomics reveals metabolic state of Bifidobacterium bifidum in the biofilm and planktonic states. LWT - Food Science and Technology 118, article number: 108772. (10.1016/j.lwt.2019.108772)
2019
- Wang, N., Yuan, L., Sadiq, F. A. and He, G. 2019. Inhibitory effect of Lactobacillus plantarum metabolites against biofilm formation by Bacillus licheniformis isolated from milk powder products. Food Control 106, article number: 106721. (10.1016/j.foodcont.2019.106721)
- Zhang, G., Zhang, W., Sun, L., Sadiq, F. A., Yang, Y., Gao, J. and Sang, Y. 2019. Preparation screening, production optimization and characterization of exopolysaccharides produced by Lactobacillus sanfranciscensis Ls-1001 isolated from Chinese traditional sourdough. International Journal of Biological Macromolecules 139, pp. 1295-1303. (10.1016/j.ijbiomac.2019.08.077)
- Sakandar, H. A., Huang, W., Kubow, S., Sadiq, F. A. and Imran, M. 2019. Comparison of bacterial communities in gliadin-degraded sourdough (Khamir) sample and non-degraded sample. Journal of Food Science and Technology 57, pp. 375-380. (10.1007/s13197-019-04030-y)
- Cui, S. et al. 2019. High-density cultivation of Lactobacillus and Bifidobacterium using an automatic feedback feeding method. LWT - Food Science and Technology 112, article number: 108232. (10.1016/j.lwt.2019.05.130)
- Sadiq, F. A., Yan, B., Tian, F., Zhao, J., Zhang, H. and Chen, W. 2019. Lactic Acid Bacteria as Antifungal and Anti‐Mycotoxigenic Agents: A Comprehensive Review. Comprehensive Reviews in Food Science and Food Safety 18(5), pp. 1403-1436. (10.1111/1541-4337.12481)
- Yuan, L., Sadiq, F. A., Burmølle, M., Wang, N. and He, G. 2019. Insights into Psychrotrophic Bacteria in Raw Milk: A Review. Journal of Food Protection 82(7), pp. 1148-1159. (10.4315/0362-028x.jfp-19-032)
- Zhang, G., Tu, J., Sadiq, F. A., Zhang, W. and Wang, W. 2019. Prevalence, genetic diversity, and technological functions of the Lactobacillus sanfranciscensis in sourdough: A review. Comprehensive Reviews in Food Science and Food Safety 18(4), pp. 1209-1226. (10.1111/1541-4337.12459)
- Zhang, G., Zhang, W., Sadiq, F. A., Arbab, S. H. and He, G. 2019. Microbiota succession and metabolite changes during the traditional sourdough fermentation of Chinese steamed bread. CyTA - Journal of Food 17(1), pp. 172-179. (10.1080/19476337.2019.1569166)
- Sakandar, H. A., Kubow, S. and Sadiq, F. A. 2019. Isolation and in-vitro probiotic characterization of fructophilic lactic acid bacteria from Chinese fruits and flowers. LWT - Food Science and Technology 104, pp. 70-75. (10.1016/j.lwt.2019.01.038)
- Sadiq, F. A., Flint, S., Sakandar, H. A. and He, G. 2019. Molecular regulation of adhesion and biofilm formation in high and low biofilm producers of Bacillus licheniformis using RNA-Seq. Biofouling: The Journal of Bioadhesion and Biofilm Research 35(2), pp. 143-158. (10.1080/08927014.2019.1575960)
- Sadiq, F. A., He, G., Sakandar, H. A., Li, Y. and Ou, K. 2019. Lactococcus lactis phages from the perspective of their diversity, thermal and biocidal resistance. International Dairy Journal 90, pp. 28-38. (10.1016/j.idairyj.2018.11.001)
- Yan, B., Sadiq, F. A., Cai, Y., Fan, D., Chen, W., Zhang, H. and Zhao, J. 2019. Microbial diversity in traditional type I sourdough and jiaozi and its influence on volatiles in Chinese steamed bread. LWT - Food Science and Technology 101, pp. 764-773. (10.1016/j.lwt.2018.12.004)
- Yan, B., Sadiq, F. A., Cai, Y., Fan, D., Zhang, H., Zhao, J. and Chen, W. 2019. Identification of key aroma compounds in type I sourdough-based Chinese steamed bread: Application of untargeted metabolomics analysisp. International Journal of Molecular Sciences 20(4), article number: 818. (10.3390/ijms20040818)
- Sakandar, H. A., Raza, H., Kubow, S., Sadiq, F. A., Huang, W. and Imran, M. 2019. Sourdough bread: A contemporary cereal fermented product. Journal of Food Processing and Preservation 43(3), article number: e13883. (10.1111/jfpp.13883)
2018
- Zhu, H., Sadiq, F. A., Yang, S. and Zhou, F. 2018. Application of ion-exchange resin as solid acid for buffer-free production of γ-aminobutyric acid using Enterococcus faecium cells. LWT 98, pp. 341--348. (10.1016/j.lwt.2018.08.066)
- Zhang, G., Wu, T., Sadiq, F. A., Yang, H., Liu, T., Ruan, H. and He, G. 2018. A study revealing the key aroma compounds of steamed bread made by Chinese traditional sourdough. Journal of Zhejiang University: Science B 17(10), pp. 787-797. (10.1631/jzus.B1600130)
- Sadiq, F. A., Flint, S. and He, G. 2018. Microbiota of milk powders and the heat resistance and spoilage potential of aerobic spore-forming bacteria. International Dairy Journal 85, pp. 159-168. (10.1016/j.idairyj.2018.06.003)
- Lei, Y., Sadiq, F. A., Burmølle, M., Liu, T. and Guoqing, H. 2018. Insights into bacterial milk spoilage with particular emphasis on the roles of heat-stable enzymes, biofilms, and quorum sensing. Journal of Food Protection 81(10), pp. 1651-1660. (10.4315/0362-028x.jfp-18-094)
- Gu, J. et al. 2018. Analysis of bacterial diversity and biogenic amines content during the fermentation processing of stinky tofu. Food Research International 111, pp. 689-698. (10.1016/j.foodres.2018.05.065)
- Yuan, L., Burmølle, M., Sadiq, F. A., Wang, N. and He, G. 2018. Interspecies variation in biofilm-forming capacity of psychrotrophic bacterial isolates from Chinese raw milk. Food Control 91, pp. 47-57. (10.1016/j.foodcont.2018.03.026)
- Lei, Y., Sadiq, F. A., Liu, T., Li, Y., Gu, J., Yang, H. and He, G. 2018. Spoilage potential of psychrotrophic bacteria isolated from raw milk and the thermo-stability of their enzymes. Journal of Zheijang University SCIENCE B - Biomedicine & Biotechnology 19, pp. 630-642. (10.1631/jzus.b1700352)
- Zhang, G., Sun, Y., Sadiq, F. A., Sakandar, H. A. and He, G. 2018. Evaluation of the effect of Saccharomyces cerevisiae on fermentation characteristics and volatile compounds of sourdough. Journal of Food Science and Technology 55(6), pp. 2079-2086. (10.1007/s13197-018-3122-1)
- Liu, T. et al. 2018. Predominant yeasts in Chinese traditional sourdough and their influence on aroma formation in Chinese steamed bread. Food Chemistry 242, pp. 404-411. (10.1016/j.foodchem.2017.09.081)
- Gu, J., Liu, T., Sadiq, F. A., Yang, H., Yuan, L., Zhang, G. and He, G. 2018. Biogenic amines content and assessment of bacterial and fungal diversity in stinky tofu – A traditional fermented soy curd. LWT - Food Science and Technology 88, pp. 26-34. (10.1016/j.lwt.2017.08.085)
2017
- Sadiq, F. A., Flint, S., Yuan, L., Li, Y., Liu, T. and He, G. 2017. Propensity for biofilm formation by aerobic mesophilic and thermophilic spore forming bacteria isolated from Chinese milk powders. International Journal of Food Microbiology 262, pp. 89-98. (10.1016/j.ijfoodmicro.2017.09.015)
- Yuan, L. et al. 2017. Psychrotrophic bacterial populations in Chinese raw dairy milk. LWT - Food Science and Technology 84, pp. 409-418. (10.1016/j.lwt.2017.05.023)
- Sadiq, F. A., Flint, S., Li, Y., Ou, K., Yuan, L. and He, G. Q. 2017. Phenotypic and genetic heterogeneity within biofilms with particular emphasis on persistence and antimicrobial tolerance.. Future Microbiology 12(12), pp. 1087-1107. (10.2217/fmb-2017-0042)
- He, G., Liu, T., Sadiq, F. A., Gu, J. and Zhang, G. 2017. Insights into the microbial diversity and community dynamics of Chinese traditional fermented foods from using high-throughput sequencing approaches. Journal of Zhejiang University: Science B 18(4), pp. 289-302. (10.1631/jzus.B1600148)
- Sadiq, F. A., Flint, S., Li, Y., Liu, T., Lei, Y., Sakandar, H. A. and He, G. 2017. New mechanistic insights into the motile-to-sessile switch in various bacteria with particular emphasis on Bacillus subtilis and Pseudomonas aeruginosa: a review. Biofouling 33(4), pp. 306-326. (10.1080/08927014.2017.1304541)
2016
- Sadiq, F. A. et al. 2016. The heat resistance and spoilage potential of aerobic mesophilic and thermophilic spore forming bacteria isolated from Chinese milk powders. International Journal of Food Microbiology 238, pp. 193-201. (10.1016/j.ijfoodmicro.2016.09.009)
- Li, Y., Sadiq, F. A., Fu, L., Zhu, H., Zhong, M. and Sohail, M. 2016. Identification of angiotensin I-converting enzyme inhibitory peptides derived from enzymatic hydrolysates of razor clam Sinonovacula constricta. Marine Drugs 14(6), article number: 110. (10.3390/md14060110)
- Liu, T., Li, Y., Chen, J., Sadiq, F. A., Zhang, G., Li, Y. and He, G. 2016. Prevalence and diversity of lactic acid bacteria in Chinese traditional sourdough revealed by culture dependent and pyrosequencing approaches. LWT - Food Science and Technology 68, pp. 91-97. (10.1016/j.lwt.2015.12.025)
- Sadiq, A., Li, Y., Liu, T., Flint, S., Zhang, G. and He, G. 2016. A RAPD based study revealing a previously unreported wide range of mesophilic and thermophilic spore formers associated with milk powders in China. International Journal of Food Microbiology 217, pp. 200-208. (10.1016/j.ijfoodmicro.2015.10.030)
2015
- Zhang, G., Sadiq, F. A., Zhu, L., Liu, T., Yang, H., Wang, X. and He, G. 2015. Investigation of microbial communities of Chinese sourdoughs using culture-dependent and DGGE approaches. Journal of Food Science 80(11), pp. M2535-M2542. (10.1111/1750-3841.13093)
- Li, Y., Sadiq, F. A., Liu, T., Chen, J. and He, G. 2015. Purification and identification of novel peptides with inhibitory effect against angiotensin I-converting enzyme and optimization of process conditions in milk fermented with the yeast Kluyveromyces marxianus. Journal of Functional Foods 16, pp. 278-288. (10.1016/j.jff.2015.04.043)
Articles
- Jia, R., Zhao, J., Tian, S., Sadiq, F. A., Lu, S., Gao, P. and Zhang, G. 2025. Enzymatic degradation of Ochratoxin A by a novel bacterium, Microbacterium esteraromaticum ASAG1016. International Journal of Food Microbiology 434, article number: 111155. (10.1016/j.ijfoodmicro.2025.111155)
- Mao, K. et al. 2024. Integrated network pharmacology and transcriptomic approach reveal the role of equol in reducing colorectal cancer via regulating multiple cell cycle genes in HCT116 cells.. International Journal of Biological Macromolecules 282(Pt 2), article number: 136832. (10.1016/j.ijbiomac.2024.136832)
- Yu, Y. et al. 2024. Comparison of the effects of three sourdough postbiotics on high-fat diet-induced intestinal damage. Food and Function 15(18), pp. 9053-9069. (10.1039/D4FO02948H)
- Cheng, T. et al. 2024. The complex world of kefir: Structural insights and symbiotic relationships. Comprehensive Reviews in Food Science and Food Safety 23(4), article number: e13364. (10.1111/1541-4337.13364)
- Gao, J., Xu, C., Tian, G., Ji, Y. H., Sadiq, F. A., Wang, K. and Sang, Y. 2024. A study revealing mechanisms behind the stone cell of Yali pear degradation by mixed‐culture fermentation of lactic acid bacteria and yeast. eFood 5(3), article number: e153. (10.1002/efd2.153)
- Sadiq, F. A., De Reu, K., Yang, N., Burmølle, M. and Heyndrickx, M. 2024. Interspecies interactions in dairy biofilms drive community structure and response against cleaning and disinfection. Biofilm 7, article number: 100195. (10.1016/j.bioflm.2024.100195)
- He, X., Yu, Y., Kemperman, R., Jimenez, L., Sadiq, F. A. and Zhang, G. 2024. Comparative genomics reveals genetic diversity and variation in metabolic traits in Fructilactobacillus sanfranciscensis strains. Microorganisms 12(5), article number: 845. (10.3390/microorganisms12050845)
- Fu, M., Gao, J., Mao, K., Sun, J., Sadiq, F. A. and Sang, Y. 2024. Interaction mechanism between surface layer protein and yeast mannan: Insights from multi-spectroscopic and molecular dynamics simulation analyses. Food Chemistry 433, article number: 137352. (10.1016/j.foodchem.2023.137352)
- Sadiq, F. . A., De Reu, K., Steenackers, H., Van de Walle, A., Burmølle, M. and Heyndrickx, M. 2023. Dynamic social interactions and keystone species shape the diversity and stability of mixed-species biofilms – an example from dairy isolates. ISME Communications 3(1), article number: 118. (10.1038/s43705-023-00328-3)
- Yongabi, D. et al. 2023. QCM‐D Viscoelastic and Adhesion Monitoring Facilitate Label‐Free and Strain‐Selective Bacterial Discrimination. physica status solidi (a) – applications and materials science 220(22), article number: 2300310. (10.1002/pssa.202300310)
- Hongchao, W. et al. 2023. Weight loss promotion in individuals with obesity through gut microbiota alterations with a multiphase modified ketogenic diet. Nutrients 15(19), article number: 4163. (10.3390/nu15194163)
- Liu, Y., Danial, M., Liu, L., Sadiq, F. A., Wei, X. and Zhang, G. 2023. Effects of co-fermentation of Lactiplantibacillus plantarum and Saccharomyces cerevisiae on digestive and quality properties of steamed bread. Foods 12, article number: 3333. (10.3390/foods12183333)
- Wang, H. et al. 2023. Modulating the human gut microbiota through hypocaloric balanced diets: An effective approach for managing obesity. Nutrients 15(14), article number: 3101. (10.3390/nu15143101)
- Jia, R. et al. 2023. Tuning Thermostability and Catalytic Efficiency of Aflatoxin-Degrading Enzyme by Error-prone PCR. Applied Microbiology and Biotechnology 107, pp. 4833-4843. (10.1007/s00253-023-12610-4)
- Sadiq, F. A., De Reu, K., Burmølle, M., Maes, S. and Heyndrickx, M. 2023. Synergistic interactions in multispecies biofilm combinations of bacterial isolates recovered from diverse food processing industries. Frontiers in Microbiology 14, article number: 1159434. (10.3389/fmicb.2023.1159434)
- Yuehong, J. et al. 2022. Pear pomace soluble dietary fiber ameliorates the negative effects of high-fat diet in mice by regulating the gut microbiota and associated metabolites. Frontiers in Nutrition 9, article number: 1025511. (10.3389/fnut.2022.1025511)
- Liu, X. et al. 2022. Application of stable isotopic and mineral elemental fingerprints in identifying the geographical origin of concentrated apple juice in China. Food Chemistry 391, article number: 133269. (10.1016/j.foodchem.2022.133269)
- Gao, J., Sadiq, F. A., Zheng, Y., Zhao, J., He, G. and Sang, Y. 2022. Biofilm-based delivery approaches and specific enrichment strategies of probiotics in the human gut. Gut Microbes 14(1), article number: 2126274. (10.1080/19490976.2022.2126274)
- Yuan, L., Wang, H., Liu, W., Sadiq, F. A. and Zhao, Y. 2022. Editorial: Multi-species biofilms in the food industry. Frontiers in Microbiology 13, article number: 1023428. (10.3389/fmicb.2022.1023428)
- Gao, J. et al. 2022. Immunoregulatory effect of Lactobacillus paracasei VL8 exopolysaccharide on RAW264.7 cells by NF-κB and MAPK pathways. Journal of Functional Foods 95, article number: 105166. (10.1016/j.jff.2022.105166)
- Tongxin, Z. et al. 2022. Novel antioxidant peptides from protein hydrolysates of scallop (Argopecten irradians) mantle using enzymatic and microbial methods: Preparation, purification, identification and characterization. LWT - Food Science and Technology 164, article number: 113636. (10.1016/j.lwt.2022.113636)
- Liu, X. et al. 2022. Origin verification of Chinese concentrated apple juice using stable isotopic and mineral elemental fingerprints coupled with chemometrics. Journal of Food Composition and Analysis 109, article number: 104424. (10.1016/j.jfca.2022.104424)
- Sadiq, F. A. et al. 2022. Trans-kingdom interactions in mixed biofilm communities. FEMS Microbiology Reviews 46(5), article number: fuac024. (10.1093/femsre/fuac024)
- Qi, Q. et al. 2022. Preparation and antioxidant properties of germinated soybean protein hydrolysates. Frontiers in Nutrition 9, article number: 866239. (10.3389/fnut.2022.866239)
- Fu, M., Mao, K., Gao, J., Wang, X., Sadiq, F. A., Li, J. and Sang, Y. 2022. Characteristics of surface layer protein from Lactobacillus kefiri HBA20 and the role in mediating interactions with Saccharomyces cerevisiae Y8. International Journal of Biological Macromolecules 201, pp. 254-261. (10.1016/j.ijbiomac.2021.12.049)
- Mao, K. et al. 2022. Bifidobacterium animalis subsp. lactis BB-12 has effect against obesity by regulating gut microbiota in two phases in human microbiota-associated rats. Frontiers in Nutrition 8, article number: 811619. (10.3389/fnut.2021.811619)
- Lei, Y., Sadiq, F. A., Wang, N., Yang, Z. and He, G. 2021. Recent advances in understanding the control of disinfectant-resistant biofilms by hurdle technology in the food industry. Critical Reviews in Food Science and Nutrition 61(22), pp. 3876-3891. (10.1080/10408398.2020.1809345)
- Guohua, Z., Qi, Q., Sadiq, F. A., Wang, W., He, X. and Wei, W. 2021. Proteomic analysis explores interactions between Lactiplantibacillus plantarum and Saccharomyces cerevisiae during sourdough fermentation. Microorganisms 9(11), article number: 2353. (10.3390/microorganisms9112353)
- Dan, W., Emmanuel, K. and Sadiq, F. A. 2021. New trends in photodynamic inactivation (PDI) combating biofilms in the food industry—A review. Foods 10(11), article number: 2587. (10.3390/foods10112587)
- Sadiq, F. A., Lu, W., Wei, C., Jianxin, Z. and Zhang, H. 2021. Transcriptional changes in Bifidobacterium bifidum involved in synergistic multispecies biofilms. Microbial Ecology 84, pp. 922-934. (10.1007/s00248-021-01904-7)
- Sadiq, F. A. and Flint, S. 2021. Dairy strains of Anoxybacillus flavithermus inhibit lipase production by Geobacillus stearothermophilus. International Dairy Journal 119, article number: 104996. (10.1016/j.idairyj.2021.104996)
- Gao, J., Xiyu, L., Zhang, G., Sadiq, F. A., Simal-Gandara, J., Xiao, J. and Sang, Y. 2021. Probiotics in the dairy industry—Advances and opportunities. Comprehensive Reviews in Food Science and Food Safety 20(4), pp. 3937-3982. (10.1111/1541-4337.12755)
- Sadiq, F. A., Lu, W., Heyndrickx, M., Flint, S., Wei, C., Jianxin, Z. and Zhang, H. 2021. Synergistic interactions prevail in multispecies biofilms formed by the human gut microbiota on mucin. FEMS Microbiology Ecology 97(8), article number: fiab096. (10.1093/femsec/fiab096)
- Pei, Z. et al. 2021. Comprehensive scanning of prophages in Lactobacillus: Distribution, diversity, antibiotic resistance genes, and linkages with CRISPR-Cas systems. mSystems 6(3), article number: 01211-20. (10.1128/msystems.01211-20)
- Sadiq, F. A., Mette, B., Heyndrickx, M., Flint, S., Lu, W. and Chen, W. 2021. Community-wide changes reflecting bacterial interspecific interactions in multispecies biofilms. Critical Reviews in Microbiology 47(3), pp. 338-358. (10.1080/1040841x.2021.1887079)
- Liu, Z. et al. 2021. Transcriptome analysis reveals the genes involved in Bifidobacterium Longum FGSZY16M3 biofilm formation. Microorganisms 9(2), article number: 385. (10.3390/microorganisms9020385)
- Sun, S. et al. 2021. HPP and SGQR peptides from silkworm pupae protein hydrolysates regulated biosynthesis of cholesterol in HepG2 cell line. Journal of Functional Foods 77, article number: 104328. (10.1016/j.jff.2020.104328)
- Jia, R., Sadiq, F. A., Liu, W., Cao, L. and Shen, Z. 2021. Protective effects of Bacillus subtilis ASAG 216 on growth performance, antioxidant capacity, gut microbiota and tissues residues of weaned piglets fed deoxynivalenol contaminated diets. Food and Chemical Toxicology 148, article number: 111962. (10.1016/j.fct.2020.111962)
- Sadiq, F. A. 2021. Is it time for microbiome-based therapies in viral infections?. Virus Research 291, article number: 198203. (10.1016/j.virusres.2020.198203)
- Yu, Z., Wang, J., Zhu, Z., Li, X., Sun, S., Wang, W. and Sadiq, A. F. 2020. Identification and characterization of two novel antioxidant peptides from silkworm pupae protein hydrolysates. European Food Research and Technology 247, pp. 343–352. (10.1007/s00217-020-03626-5)
- Pei, Z. et al. 2020. Identification, characterization, and phylogenetic analysis of eight new inducible prophages in Lactobacillus. Virus Research 286, article number: 198003. (10.1016/j.virusres.2020.198003)
- Yi, Z., Sadiq, F. A., Wang, H., Zhao, J., Zhang, H., Lu, W. and Chen, W. 2020. Establishment and evaluation of a method for efficient screening of Clostridium butyricum. Folia Microbiologica 65, pp. 917-924. (10.1007/s12223-020-00803-7)
- Guo, M. et al. 2020. Effects of noni fruit and fermented noni juice against acute alcohol induced liver injury in mice. Journal of Functional Foods 70, article number: 103995. (10.1016/j.jff.2020.103995)
- Du, X. et al. 2020. Two‐dimensional liquid chromatography analysis of all‐trans‐, 9‐cis‐, and 13‐cis‐astaxanthin in raw extracts from Phaffia rhodozyma. Journal of Separation Science 43(16), pp. 3206-3215. (10.1002/jssc.202000257)
- Lei, Y., Wang, N., Sadiq, F. A. and Guoqing, H. 2020. Interspecies interactions in dual-species biofilms formed by psychrotrophic bacteria and the tolerance of sessile communities to disinfectants. Journal of Food Protection 83(6), pp. 951-958. (10.4315/0362-028x.jfp-19-396)
- Lei, Y., Wang, N., Sadiq, F. A. and Guoqing, H. 2020. RNA sequencing reveals the involvement of quorum sensing in dairy spoilage caused by psychrotrophic bacteria. LWT - Food Science and Technology 127, article number: 109384. (10.1016/j.lwt.2020.109384)
- Wang, N., Wang, W., Sadiq, F. A., Wang, S., Caiqin, L. and Jianchang, J. 2020. Involvement of Nrf2 and Keap1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent peptides from soft-shelled turtle. Process Biochemistry 92, pp. 174-181. (10.1016/j.procbio.2019.12.022)
- Yang, H., Sadiq, F. A., Liu, T., Zhang, G. and He, G. 2020. Use of physiological and transcriptome analysis to infer the interactions between Saccharomyces cerevisiae and Lactobacillus sanfranciscensis isolated from Chinese traditional sourdoughs. LWT - Food Science and Technology 126, article number: 109268. (10.1016/j.lwt.2020.109268)
- Wang, N., Sadiq, F. A., Li, S., He, G. and Yuan, L. 2020. Tandem mass tag-based quantitative proteomics reveals the regulators in biofilm formation and biofilm control of Bacillus licheniformis. Food Control 110, article number: 107029. (10.1016/j.foodcont.2019.107029)
- Flint, S. et al. 2020. Bacterial fouling in dairy processing. International Dairy Journal 101, article number: 104593. (10.1016/j.idairyj.2019.104593)
- Sadiq, F. A., Yan, B., Zhao, J., Zhang, H. and Chen, W. 2020. Untargeted metabolomics reveals metabolic state of Bifidobacterium bifidum in the biofilm and planktonic states. LWT - Food Science and Technology 118, article number: 108772. (10.1016/j.lwt.2019.108772)
- Wang, N., Yuan, L., Sadiq, F. A. and He, G. 2019. Inhibitory effect of Lactobacillus plantarum metabolites against biofilm formation by Bacillus licheniformis isolated from milk powder products. Food Control 106, article number: 106721. (10.1016/j.foodcont.2019.106721)
- Zhang, G., Zhang, W., Sun, L., Sadiq, F. A., Yang, Y., Gao, J. and Sang, Y. 2019. Preparation screening, production optimization and characterization of exopolysaccharides produced by Lactobacillus sanfranciscensis Ls-1001 isolated from Chinese traditional sourdough. International Journal of Biological Macromolecules 139, pp. 1295-1303. (10.1016/j.ijbiomac.2019.08.077)
- Sakandar, H. A., Huang, W., Kubow, S., Sadiq, F. A. and Imran, M. 2019. Comparison of bacterial communities in gliadin-degraded sourdough (Khamir) sample and non-degraded sample. Journal of Food Science and Technology 57, pp. 375-380. (10.1007/s13197-019-04030-y)
- Cui, S. et al. 2019. High-density cultivation of Lactobacillus and Bifidobacterium using an automatic feedback feeding method. LWT - Food Science and Technology 112, article number: 108232. (10.1016/j.lwt.2019.05.130)
- Sadiq, F. A., Yan, B., Tian, F., Zhao, J., Zhang, H. and Chen, W. 2019. Lactic Acid Bacteria as Antifungal and Anti‐Mycotoxigenic Agents: A Comprehensive Review. Comprehensive Reviews in Food Science and Food Safety 18(5), pp. 1403-1436. (10.1111/1541-4337.12481)
- Yuan, L., Sadiq, F. A., Burmølle, M., Wang, N. and He, G. 2019. Insights into Psychrotrophic Bacteria in Raw Milk: A Review. Journal of Food Protection 82(7), pp. 1148-1159. (10.4315/0362-028x.jfp-19-032)
- Zhang, G., Tu, J., Sadiq, F. A., Zhang, W. and Wang, W. 2019. Prevalence, genetic diversity, and technological functions of the Lactobacillus sanfranciscensis in sourdough: A review. Comprehensive Reviews in Food Science and Food Safety 18(4), pp. 1209-1226. (10.1111/1541-4337.12459)
- Zhang, G., Zhang, W., Sadiq, F. A., Arbab, S. H. and He, G. 2019. Microbiota succession and metabolite changes during the traditional sourdough fermentation of Chinese steamed bread. CyTA - Journal of Food 17(1), pp. 172-179. (10.1080/19476337.2019.1569166)
- Sakandar, H. A., Kubow, S. and Sadiq, F. A. 2019. Isolation and in-vitro probiotic characterization of fructophilic lactic acid bacteria from Chinese fruits and flowers. LWT - Food Science and Technology 104, pp. 70-75. (10.1016/j.lwt.2019.01.038)
- Sadiq, F. A., Flint, S., Sakandar, H. A. and He, G. 2019. Molecular regulation of adhesion and biofilm formation in high and low biofilm producers of Bacillus licheniformis using RNA-Seq. Biofouling: The Journal of Bioadhesion and Biofilm Research 35(2), pp. 143-158. (10.1080/08927014.2019.1575960)
- Sadiq, F. A., He, G., Sakandar, H. A., Li, Y. and Ou, K. 2019. Lactococcus lactis phages from the perspective of their diversity, thermal and biocidal resistance. International Dairy Journal 90, pp. 28-38. (10.1016/j.idairyj.2018.11.001)
- Yan, B., Sadiq, F. A., Cai, Y., Fan, D., Chen, W., Zhang, H. and Zhao, J. 2019. Microbial diversity in traditional type I sourdough and jiaozi and its influence on volatiles in Chinese steamed bread. LWT - Food Science and Technology 101, pp. 764-773. (10.1016/j.lwt.2018.12.004)
- Yan, B., Sadiq, F. A., Cai, Y., Fan, D., Zhang, H., Zhao, J. and Chen, W. 2019. Identification of key aroma compounds in type I sourdough-based Chinese steamed bread: Application of untargeted metabolomics analysisp. International Journal of Molecular Sciences 20(4), article number: 818. (10.3390/ijms20040818)
- Sakandar, H. A., Raza, H., Kubow, S., Sadiq, F. A., Huang, W. and Imran, M. 2019. Sourdough bread: A contemporary cereal fermented product. Journal of Food Processing and Preservation 43(3), article number: e13883. (10.1111/jfpp.13883)
- Zhu, H., Sadiq, F. A., Yang, S. and Zhou, F. 2018. Application of ion-exchange resin as solid acid for buffer-free production of γ-aminobutyric acid using Enterococcus faecium cells. LWT 98, pp. 341--348. (10.1016/j.lwt.2018.08.066)
- Zhang, G., Wu, T., Sadiq, F. A., Yang, H., Liu, T., Ruan, H. and He, G. 2018. A study revealing the key aroma compounds of steamed bread made by Chinese traditional sourdough. Journal of Zhejiang University: Science B 17(10), pp. 787-797. (10.1631/jzus.B1600130)
- Sadiq, F. A., Flint, S. and He, G. 2018. Microbiota of milk powders and the heat resistance and spoilage potential of aerobic spore-forming bacteria. International Dairy Journal 85, pp. 159-168. (10.1016/j.idairyj.2018.06.003)
- Lei, Y., Sadiq, F. A., Burmølle, M., Liu, T. and Guoqing, H. 2018. Insights into bacterial milk spoilage with particular emphasis on the roles of heat-stable enzymes, biofilms, and quorum sensing. Journal of Food Protection 81(10), pp. 1651-1660. (10.4315/0362-028x.jfp-18-094)
- Gu, J. et al. 2018. Analysis of bacterial diversity and biogenic amines content during the fermentation processing of stinky tofu. Food Research International 111, pp. 689-698. (10.1016/j.foodres.2018.05.065)
- Yuan, L., Burmølle, M., Sadiq, F. A., Wang, N. and He, G. 2018. Interspecies variation in biofilm-forming capacity of psychrotrophic bacterial isolates from Chinese raw milk. Food Control 91, pp. 47-57. (10.1016/j.foodcont.2018.03.026)
- Lei, Y., Sadiq, F. A., Liu, T., Li, Y., Gu, J., Yang, H. and He, G. 2018. Spoilage potential of psychrotrophic bacteria isolated from raw milk and the thermo-stability of their enzymes. Journal of Zheijang University SCIENCE B - Biomedicine & Biotechnology 19, pp. 630-642. (10.1631/jzus.b1700352)
- Zhang, G., Sun, Y., Sadiq, F. A., Sakandar, H. A. and He, G. 2018. Evaluation of the effect of Saccharomyces cerevisiae on fermentation characteristics and volatile compounds of sourdough. Journal of Food Science and Technology 55(6), pp. 2079-2086. (10.1007/s13197-018-3122-1)
- Liu, T. et al. 2018. Predominant yeasts in Chinese traditional sourdough and their influence on aroma formation in Chinese steamed bread. Food Chemistry 242, pp. 404-411. (10.1016/j.foodchem.2017.09.081)
- Gu, J., Liu, T., Sadiq, F. A., Yang, H., Yuan, L., Zhang, G. and He, G. 2018. Biogenic amines content and assessment of bacterial and fungal diversity in stinky tofu – A traditional fermented soy curd. LWT - Food Science and Technology 88, pp. 26-34. (10.1016/j.lwt.2017.08.085)
- Sadiq, F. A., Flint, S., Yuan, L., Li, Y., Liu, T. and He, G. 2017. Propensity for biofilm formation by aerobic mesophilic and thermophilic spore forming bacteria isolated from Chinese milk powders. International Journal of Food Microbiology 262, pp. 89-98. (10.1016/j.ijfoodmicro.2017.09.015)
- Yuan, L. et al. 2017. Psychrotrophic bacterial populations in Chinese raw dairy milk. LWT - Food Science and Technology 84, pp. 409-418. (10.1016/j.lwt.2017.05.023)
- Sadiq, F. A., Flint, S., Li, Y., Ou, K., Yuan, L. and He, G. Q. 2017. Phenotypic and genetic heterogeneity within biofilms with particular emphasis on persistence and antimicrobial tolerance.. Future Microbiology 12(12), pp. 1087-1107. (10.2217/fmb-2017-0042)
- He, G., Liu, T., Sadiq, F. A., Gu, J. and Zhang, G. 2017. Insights into the microbial diversity and community dynamics of Chinese traditional fermented foods from using high-throughput sequencing approaches. Journal of Zhejiang University: Science B 18(4), pp. 289-302. (10.1631/jzus.B1600148)
- Sadiq, F. A., Flint, S., Li, Y., Liu, T., Lei, Y., Sakandar, H. A. and He, G. 2017. New mechanistic insights into the motile-to-sessile switch in various bacteria with particular emphasis on Bacillus subtilis and Pseudomonas aeruginosa: a review. Biofouling 33(4), pp. 306-326. (10.1080/08927014.2017.1304541)
- Sadiq, F. A. et al. 2016. The heat resistance and spoilage potential of aerobic mesophilic and thermophilic spore forming bacteria isolated from Chinese milk powders. International Journal of Food Microbiology 238, pp. 193-201. (10.1016/j.ijfoodmicro.2016.09.009)
- Li, Y., Sadiq, F. A., Fu, L., Zhu, H., Zhong, M. and Sohail, M. 2016. Identification of angiotensin I-converting enzyme inhibitory peptides derived from enzymatic hydrolysates of razor clam Sinonovacula constricta. Marine Drugs 14(6), article number: 110. (10.3390/md14060110)
- Liu, T., Li, Y., Chen, J., Sadiq, F. A., Zhang, G., Li, Y. and He, G. 2016. Prevalence and diversity of lactic acid bacteria in Chinese traditional sourdough revealed by culture dependent and pyrosequencing approaches. LWT - Food Science and Technology 68, pp. 91-97. (10.1016/j.lwt.2015.12.025)
- Sadiq, A., Li, Y., Liu, T., Flint, S., Zhang, G. and He, G. 2016. A RAPD based study revealing a previously unreported wide range of mesophilic and thermophilic spore formers associated with milk powders in China. International Journal of Food Microbiology 217, pp. 200-208. (10.1016/j.ijfoodmicro.2015.10.030)
- Zhang, G., Sadiq, F. A., Zhu, L., Liu, T., Yang, H., Wang, X. and He, G. 2015. Investigation of microbial communities of Chinese sourdoughs using culture-dependent and DGGE approaches. Journal of Food Science 80(11), pp. M2535-M2542. (10.1111/1750-3841.13093)
- Li, Y., Sadiq, F. A., Liu, T., Chen, J. and He, G. 2015. Purification and identification of novel peptides with inhibitory effect against angiotensin I-converting enzyme and optimization of process conditions in milk fermented with the yeast Kluyveromyces marxianus. Journal of Functional Foods 16, pp. 278-288. (10.1016/j.jff.2015.04.043)
Ymchwil
Ar hyn o bryd rwy'n canolbwyntio ar astudio rhyngweithiadau microbaidd mewn bioffilmiau rhywogaethau cymysg o berthnasedd clinigol, fel y rhai a geir mewn clwyfau heintiedig a chronig. Fy nod yw archwilio ysgogwyr cydfodoli bacteriol o fewn y bioffilmiau hyn a'u cydddibyniaethau, yn enwedig yng nghyd-destun goddefgarwch a gwrthficrobaidd. Yn ogystal, rwy'n ceisio datblygu strategaethau i dargedu'r cysylltiadau cymdeithasol sy'n ganolog i gydfodoli'r cymunedau hyn.
Prosiectau ymchwil cyfredol:
- Ymddiriedolaeth Wellcome (2025-2027): Deall rhyngweithiadau rhwng rhywogaethau mewn bioffilmiau rhywogaethau cymysg sy'n gysylltiedig â heintiau cronig mewn perthynas ag ymwrthedd gwrthficrobaidd (Prif Ymchwilydd)
Prosiectau ymchwil blaenorol:
- Y Comisiwn Ewropeaidd (2021-2023) Mae deall bioffilmiau amlrywogaethau'r diwydiant bwyd yn hanfodol ar gyfer rheoli materion diogelwch ac ansawdd bwyd sy'n gysylltiedig â bioffilm (Deiliad Grant; € 178,320).
- Grant Sefydliad Gwyddoniaeth Ôl-ddoethurol Tsieina Potensial gwrthffyngol ac antimycotoxigenig bacteria asid lactig (Deiliad Grant; ¥50,000).
Addysgu
Rwy'n ymwneud ag addysgu ac asesu rhaglenni israddedig ac ôl-raddedig (BDS ac MSc Mewnblanoleg) gyda phwyslais arbennig ar Bioffilmiau, Gwyddorau Moleciwlaidd, a Microbioleg clefydau Periodontal.
Bywgraffiad
Swyddi academaidd
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2024 - Yn bresennol: Darlithydd (Athro Cynorthwyol) mewn Bioffilmiau Microbaidd, Ysgol Deintyddiaeth, Prifysgol Caerdydd, y DU.
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2024: Uwch Wyddonydd Ymchwil, Sefydliad Ymchwil Fflandrys ar gyfer Amaethyddiaeth, Pysgodfeydd a Bwyd (ILVO), Gwlad Belg.
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2022 – 2024: Marie Skłodowska-Curie Actions (MSCA), Sefydliad Ymchwil Fflandrys ar gyfer Amaethyddiaeth, Pysgodfeydd a Bwyd (ILVO), Gwlad Belg.
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2023: Ymweld Ymchwilydd, Prifysgol Copenhagen, Denmarc.
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2022: Ymweld Ymchwilydd, KU Leuven, Gwlad Belg.
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2018 – 2021: Cydymaith Ymchwil Ôl-ddoethurol, Prifysgol Jiangnan, Wuxi, Tsieina.
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2017: Cymrawd Ymchwil, Prifysgol Massey, Seland Newydd.
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2014-2018: Cynorthwy-ydd Ymchwil (rhan-amser), Prifysgol Zhejiang, Hangzhou, Tsieina.
Addysg a Chymwysterau
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2014-2018: PhD (Gwyddoniaeth Bwyd) - Prifysgol Zhejiang, Tsieina.
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2011-2013: MSc (Diogelwch Bwyd a Rheoli Ansawdd) - Prifysgol Greenwich, UK.
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2007-2011: BSc (Anrh) (Technoleg Bwyd) - Prifysgol Amaethyddiaeth Faisalabad, Pacistan
Anrhydeddau a dyfarniadau
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Enillydd Grant Teithio FEMS i fynychu cynhadledd Microbe ASM yn Houston, Texas, UDA, ym mis Mehefin 2023
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Derbynnydd Cymrodoriaeth Gweithredoedd Marie Skłodowska-Curie (MSCA) gan y Comisiwn Ewropeaidd, gan sgorio 98/100 a derbyn grant o € 178,320 (Grant ID: 101025683)
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Dyfarnwyd y Grant Ymchwil a Hyfforddiant FEMS (2021).
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Dyfarnwyd y Rhaglen Cymorth Talent Arloesi Ôl-ddoethurol (2018) gan Lywodraeth Tsieina, gan dderbyn ¥ 600,000.
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Dyfarnwyd ysgoloriaeth PhD a ariennir yn llawn gan Lywodraeth Tsieina (Cyngor Ysgoloriaeth Tsieina) i gwblhau fy PhD ym Mhrifysgol Zhejiang (2014-2018).
Aelodaethau proffesiynol
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Cymdeithas Microbioleg Gwlad Belg (BSM).
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Ffederasiwn Cymdeithasau Microbiolegol Ewrop (FEMS).
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Cymdeithas Microbioleg America (ASM).
Pwyllgorau ac adolygu
Adolygydd ar gyfer y cylchgronau canlynol:
- Adolygiadau Cynhwysfawr mewn Gwyddor Bwyd a Diogelwch Bwyd
- BMC Microbioleg
- Ffiniau mewn Microbioleg
- Ymchwil Bwyd Rhyngwladol
- LWT Food Science and Tecnology
- Llythyrau mewn Microbioleg Gymhwysol
- International Dairy Journal
- Journal of Microbioleg Gymhwysol
Aelod o'r Bwrdd Golygyddol ar gyfer y cyfnodolion canlynol:
- Golygydd Cyswllt Frontiers in Microbiology
- Aelod bwrdd golygyddol o BMC Microbioleg
Rôl gwerthuswr arbenigol:
- Arfarnwr arbenigol ar gyfer coleg adolygu FWO (Sefydliad Ymchwil Fflandrys, Gwlad Belg) ar gyfer ceisiadau cymrodoriaeth postdoc (2024-2026).
Meysydd goruchwyliaeth
Dyma rai o'r pynciau ymchwil y mae gennyf ddiddordeb ynddynt; Fodd bynnag, rwyf bob amser yn agored i drafodaethau pellach ar feysydd cysylltiedig:
- Datod ecoleg bioffilm o heintiau mewn lleoliadau clinigol.
- Rhyngweithiadau microbaidd, gan gynnwys rhyngweithiadau trawsdeyrnasol, mewn bioffilmiau amlrywogaeth mewn lleoliadau clinigol a diwydiannol.
- Ymddangosiad goddefgarwch gwrthficrobaidd ac esblygiad ymwrthedd gwrthficrobaidd mewn bioffilmiau rhywogaethau cymysg.
- Datblygu therapïau newydd yn erbyn bioffilmiau sy'n gysylltiedig â chlwyfau acíwt a chronig.
- Datblygu probiotegau wedi'u targedu i frwydro yn erbyn cymunedau microbaidd annymunol.
- Deall metabolaidd a dibyniaethau eraill ymhlith micro-organebau amrywiol mewn bioffilmiau.
- Ymchwilio i yrwyr cydfodolaeth bacteriol mewn bioffilmiau, cemegol a biolegol.
Agored i dderbyn ceisiadau PhD gan Gyngor Ysgoloriaethau Tsieina (CSC)
Mae Prifysgol Caerdydd yn cynnig ysgoloriaethau ffioedd dysgu i fyfyrwyr llwyddiannus Cyngor Ysgoloriaethau Tsieina nad ydynt wedi cofrestru ar hyn o bryd mewn rhaglen PhD. Dylid gwneud ceisiadau yn unol â chanllawiau CSC. Ymgeisiwch yma Ffurflen gais PhD Prifysgol Caerdydd. Cysylltwch â mi ymlaen llaw os oes gennych ddiddordeb mewn prosiect PhD sy'n seiliedig ar ficrobioleg.
Contact Details
SadiqF@caerdydd.ac.uk
Ysbyty Deintyddol y Brifysgol, Llawr 5, Ystafell 5F.03, Parc y Mynydd Bychan, Caerdydd, CF14 4XY
Ysbyty Deintyddol y Brifysgol, Llawr 5, Ystafell 5F.03, Parc y Mynydd Bychan, Caerdydd, CF14 4XY
Themâu ymchwil
Arbenigeddau
- Microbioleg Bwyd
- Bioffilmiau
- Ecoleg ficrobaidd
- Eplesiad
- Microbioleg clinigol