Dr Emma Thomas-Jones
Research Fellow - Senior Trial Manager in Infections and Devices
- Thomas-JonesE@caerdydd.ac.uk
- Neuadd Meirionnydd, Ystafell 708F, Ysbyty Athrofaol Cymru, Parc y Mynydd Bychan, Caerdydd, CF14 4YS
- Siarad Cymraeg
- Ar gael fel goruchwyliwr ôl-raddedig
Trosolwyg
Rwy'n Brif Gymrawd Ymchwil ac yn Ddirprwy Gyfarwyddwr ar gyfer Is-adran Ymchwil Heintiau, Llid ac Imiwnedd yn y Ganolfan Treialon Ymchwil .
Mae fy meysydd ymchwil mewn heintiau cyffredin mewn gofal sylfaenol (e.e. UTI), biofarcwyr ar gyfer heintiau a sepsis. Rwy'n cynnal ymchwil sy'n seiliedig ar dystiolaeth yn profi effeithiolrwydd ymyriadau gyda'r nod o leihau ymwrthedd gwrthfiotigau.
Mae gennyf wybodaeth a phrofiad helaeth mewn methodoleg treialon a llywodraethu ymchwil.
Cyhoeddiad
2023
- Ingram, J. R. et al. 2023. Treatment of hidradenitis suppurativa evaluation study (THESEUS): a prospective cohort study. British Journal of Dermatology (10.1093/bjd/ljad388)
- Leighton, P. et al. 2023. Research priorities in the management of Hidradenitis Suppurativa [Research Letter]. British Journal of Dermatology 189(3), pp. 343-345. (10.1093/bjd/ljad152)
- Schoenbuchner, S. M., Huang, C., Waldron, C., Thomas-Jones, E., Hood, K., Carrol, E. D. and Pallmann, P. 2023. Biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: statistical analysis plan for the BATCH trial and PRECISE sub-study. Trials 24(1), article number: 364. (10.1186/s13063-022-06956-9)
2022
- Lenihan, R. A. F. et al. 2022. Mid-regional pro-adrenomedullin in combination with pediatric early warning scores for risk stratification of febrile children presenting to the emergency department: secondary analysis of a nonprespecified United Kingdom cohort study. Pediatric Critical Care Medicine 23(12), pp. 980-989. (10.1097/PCC.0000000000003075)
- Gwilym, B. L. et al. 2022. Short-term risk prediction after major lower limb amputation: PERCEIVE study. BJS Open 109(12), pp. 1300-1311. (10.1093/bjs/znac309)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients (PEACH): protocol for a retrospective observational study. Methods and Protocols 5(6), article number: 95. (10.3390/mps5060095)
- Chatoo, S. A., Thomas-Jones, E., Pallmann, P. and Euden, J. 2022. Antibiotic prescribing in hospitalized patients with COVID-19 as a function of inflammatory markers in wave 1 versus wave 2: a systematic review. Presented at: BSAC Spring Conference 2022, 10 - 11 May 2022, Vol. 4. Vol. S.2., (10.1093/jacamr/dlac053.012)
- Euden, J. et al. 2022. PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial. BMJ Open 12(6), article number: e063424. (10.1136/bmjopen-2022-063424)
- Abbott, R. A. et al. 2022. Observational study to estimate the proportion of surgical site infection following excision of ulcerated skin tumours (OASIS study). Clinical and Experimental Dermatology 47(5), pp. 882-888. (10.1111/ced.15037)
- Totty, J. P., Matin, R. N., Wernham, A., Ray, R., Thomas-Jones, E. and Abbott, R. A. 2022. Use of perioperative prophylactic antibiotics following excision of ulcerated skin lesions in the UK: a national, multispeciality survey of clinicians. Clinical and Experimental Dermatology 47(5), pp. 957-959. (10.1111/ced.15075)
- Llewelyn, M. J. et al. 2022. Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data. Journal of Antimicrobial Chemotherapy 77(4), pp. 1189-1196. (10.1093/jac/dkac017)
- Gillespie, D. et al. 2022. Associations with post-consultation health-status in primary care managed acute exacerbation of COPD. International Journal of Chronic Obstructive Pulmonary Disease 2022(17), pp. 383-394. (10.2147/COPD.S340710)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalized patients during the first wave of COVID-19: the PEACH study. Presented at: Infection 2021: BSAC Winter Conference, Virtual, 9-10 December 2021, Vol. 4. Vol. 1., (10.1093/jacamr/dlac004.013)
- Allen, D. et al. 2022. Development, implementation and evaluation of an early warning system improvement programme for children in hospital: the PUMA mixed-methods study. Health and Social Care Delivery Research 10(1) (10.3310/CHCK4556)
- Waldron, C. et al. 2022. Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial. BMJ Open 12(1), article number: e047490. (10.1136/bmjopen-2020-047490)
- Milosevic, S. et al. 2022. PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation: a collaboratiVE study (PERCEIVE)—protocol for the PERCEIVE qualitative study. BMJ Open 12(1), article number: e053159. (10.1136/bmjopen-2021-053159)
2021
- Milosevic, S. et al. 2021. Exploring patients’ experiences of analgesia after major lower limb amputation: A qualitative study. BMJ Open 11, article number: e054618. (10.1136/bmjopen-2021-054618)
- Gwilym, B. L. et al. 2021. The PERCEIVE quantitative study: PrEdiction of Risk and Communication of outcome following major lower-limb amputation: protocol for a collaboratiVE study. BJS Open 5(6), article number: zrab118. (10.1093/bjsopen/zrab118)
- Richards, O. et al. 2021. Procalcitonin increase is associated with the development of critical care-acquired infections in COVID-19 ARDS. Antibiotics 10(11), article number: 1425. (10.3390/antibiotics10111425)
- Phillips, R. et al. 2021. Cohort profile: The UK COVID-19 Public Experiences (COPE) prospective longitudinal mixed-methods study of health and well-being during the SARSCoV2 coronavirus pandemic. PLoS ONE 16(10), article number: e0258484. (10.1371/journal.pone.0258484)
- Milosevic, S. et al. 2021. Managing LUTS in primary care: qualitative study of GPs’ and patients’ experiences. British Journal of General Practice 71(710), pp. e685-e692. (10.3399/BJGP.2020.1043)
- Preece, R. et al. 2021. A systematic review and narrative synthesis of risk prediction tools used to estimate mortality, morbidity, and other outcomes following major lower limb amputation. European Journal of Vascular and Endovascular Surgery 62(1), pp. 127-135. (10.1016/j.ejvs.2021.02.038)
- Milosevic, S. et al. 2021. Conducting invasive urodynamics in primary care: Qualitative interview study examining experiences of patients and healthcare professionals. Diagnostic and Prognostic Research 5, article number: 10. (10.1186/s41512-021-00100-y)
- Powell, N. et al. 2021. Use of procalcitonin during the first wave of COVID-19 in the acute NHS hospitals: a retrospective observational study. Antibiotics 10(5), article number: 516. (10.3390/antibiotics10050516)
- Gwilym, B. et al. 2021. PERCEIVE: PrEdiction of Risk and Communication of outcome following major lower limb amputation - a collaboratIVE study. Presented at: National Research Collaborative Meeting 2020 (NRCM 2020), Virtual, 19 November - 10 December 2020, Vol. 5. Vol. Supple. Wiley, (10.1093/bjsopen/zrab032.089)
2020
- Pell, B. et al. 2020. PRImary care Management of lower Urinary tract Symptoms in men: protocol for development and validation of a diagnostic and clinical decision support tool (the PriMUS study). BMJ 10(6), article number: e037634. (10.1136/bmjopen-2020-037634)
- Ambler, G. K., Thomas-Jones, E., Edwards, A. G. K. and Twine, C. P. 2020. Prognostic risk modelling for patients undergoing major lower limb amputation: an analysis of the UK National Vascular Registry. European Journal of Vascular and Endovascular Surgery 59(4), pp. 606-613. (10.1016/j.ejvs.2019.12.006)
2019
- Brookes-Howell, L. et al. 2019. Challenges in managing urinary tract infection and the potential of a point-of-care test guided care in primary care: an international qualitative study. BJGP Open 3(2), article number: 18X101630. (10.3399/bjgpopen18X101630)
2018
- Santer, M. et al. 2018. Adding emollient bath additives to standard eczema management for children with eczema: the BATHE RCT. Health Technology Assessment 22(57) (10.3310/hta22570)
- Francis, N. A. et al. 2018. Oral steroids for hearing loss associated with otitis media with effusion in children aged 2 8 years: the OSTRICH RCT. Health Technology Assessment 22(61) (10.3310/hta22610)
- Bosanquet, D. C. et al. 2018. Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. British Journal of Pain 12(4), pp. 257-258. (10.1177/2049463718800736)
- Stuart, B. et al. 2018. Feasibility of weekly participant-reported data collection in a pragmatic randomised controlled trial in primary care: Experiences from the BATHE trial (Bath Additives for the Treatment of cHildhood Eczema). Trials 19, article number: 582.
- Francis, N. A. et al. 2018. Oral steroids for resolution of otitis media with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial. Lancet 392(10147), pp. 557-568. (10.1016/S0140-6736(18)31490-9)
- Prout, H. C. et al. 2018. Patient understanding and acceptability of an early lung cancer diagnosis trial: a qualitative study. Trials 19, article number: 419. (10.1186/s13063-018-2803-4)
- Gillespie, D., Francis, N. A., Carrol, E. D., Thomas-Jones, E., Butler, C. C. and Hood, K. 2018. Use of co-primary outcomes for trials of antimicrobial stewardship interventions. Lancet Infectious Diseases 18(6), pp. 595-597. (10.1016/S1473-3099(18)30289-5)
- Santer, M. et al. 2018. Emollient bath additives for the treatment of childhood eczema (BATHE): multicentre pragmatic parallel group randomised controlled trial of clinical and cost effectiveness. BMJ 361, article number: k1332. (10.1136/bmj.k1332)
- Butler, C. C. et al. 2018. Point-of-care urine culture for managing urinary tract infection in primary care: a randomised controlled trial of clinical and cost-effectiveness. British Journal of General Practice 68(669), pp. e268-e278. (10.3399/bjgp18X695285)
- Ingram, J. et al. 2018. Levels of wound calprotectin and other inflammatory biomarkers aid in deciding which patients with a diabetic foot ulcer need antibiotic therapy (INDUCE study). Diabetic Medicine 35(2), pp. 255-261. (10.1111/dme.13431)
2017
- Butler, C. C. et al. 2017. Variations in presentation, management, and patient outcomes of urinary tract infection: a prospective four-country primary care observational cohort study. British Journal of General Practice 67(665), pp. e830-e841. (10.3399/bjgp17X693641)
- Ambler, G. K., Bosanquet, D. C., Brookes-Howell, L., Thomas-Jones, R. E., Waldron, C., Edwards, A. G. K. and Twine, C. P. 2017. Development of a core outcome set for studies involving patients undergoing major lower limb amputation for peripheral arterial disease: study protocol for a systematic review and identification of a core outcome set using a Delphi survey. Trials 18(1), article number: 628. (10.1186/s13063-017-2358-9)
- Bosanquet, D. C. et al. 2017. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 18, article number: 629. (10.1186/s13063-017-2357-x)
- Shepherd, V., Thomas-Jones, E., Ridd, M. J., Hood, K., Addison, K. and Francis, N. 2017. Impact of a deferred recruitment model in a randomised controlled trial in primary care (CREAM study). Trials 18(1), article number: 533. (10.1186/s13063-017-2284-x)
- Hollingworth, W. et al. 2017. The diagnosis of urinary tract infection in young children (DUTY) study clinical rule: economic evaluation. Value in Health 20(4), pp. 556-566. (10.1016/j.jval.2017.01.003)
- Francis, N. A. et al. 2017. Oral and topical antibiotics for clinically infected eczema in children: a pragmatic randomized controlled trial in ambulatory care. Annals of Family Medicine 15(2), pp. 124-130. (10.1370/afm.2038)
2016
- Glover, G. W. et al. 2016. Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest - an analysis of the TTM trial data. Critical care (London, England) 20(1), article number: 381. (10.1186/s13054-016-1552-6)
- Francis, N. A. et al. 2016. A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: the ChildRen with Eczema, Antibiotic Management (CREAM) study. Health Technology Assessment 20(19), pp. 1-84. (10.3310/hta20190)
- Waldron, C. et al. 2016. Oral Steroids for the Resolution of Otitis Media with Effusion (OME) in Children (OSTRICH): study protocol for a randomised controlled trial. Trials 17, article number: 115. (10.1186/s13063-016-1236-1)
2015
- Gillespie, D. et al. 2015. Antibiotic prescribing and associated diarrhoea: a prospective cohort study of care home residents. Age and Ageing 44(5), pp. 853-860. (10.1093/ageing/afv072)
- Butler, C. C. et al. 2015. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. British Journal of General Practice 65(633), pp. e217-e223. (10.3399/bjgp15X684361)
2014
- Bates, J. et al. 2014. Point of care testing for urinary tract infection in primary care (POETIC): protocol for a randomised controlled trial of the clinical and cost effectiveness of FLEXICULT (TM) informed management of uncomplicated UTI in primary care. BMC Family Practice 15, pp. -., article number: 187. (10.1186/s12875-014-0187-4)
2013
- Bates, J. et al. 2013. Effects of an optimised POCT guided diagnostic and treatment strategy for symptoms of uncomplicated UTI on use of appropriate antibiotics and uptake into primary care practice. [Abstract]. Trials 14(S1), pp. -., article number: P10. (10.1186/1745-6215-14-S1-P10)
- Waldron, C. et al. 2013. Recruitment to diagnosis of urinary tract infections in young children (DUTY) study: an evaluation of the successful methods used in a primary care, prospective cohort study. [Abstract]. Trials 14(S1), pp. -., article number: P37. (10.1186/1745-6215-14-S1-P37)
2012
- Robling, M. R. et al. 2012. The effect of the Talking Diabetes consulting skills intervention on glycaemic control and quality of life in children with type 1 diabetes: cluster randomised controlled trial (DEPICTED study). British Medical Journal 344, article number: e2359. (10.1136/bmj.e2359)
2011
- Gregory, J. W. et al. 2011. Development and evaluation by a cluster randomised trial of a psychosocial intervention in children and teenagers experiencing diabetes: The DEPICTED study. Health Technology Assessment 15(29), pp. 1-202. (10.3310/hta15290)
Articles
- Ingram, J. R. et al. 2023. Treatment of hidradenitis suppurativa evaluation study (THESEUS): a prospective cohort study. British Journal of Dermatology (10.1093/bjd/ljad388)
- Leighton, P. et al. 2023. Research priorities in the management of Hidradenitis Suppurativa [Research Letter]. British Journal of Dermatology 189(3), pp. 343-345. (10.1093/bjd/ljad152)
- Schoenbuchner, S. M., Huang, C., Waldron, C., Thomas-Jones, E., Hood, K., Carrol, E. D. and Pallmann, P. 2023. Biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: statistical analysis plan for the BATCH trial and PRECISE sub-study. Trials 24(1), article number: 364. (10.1186/s13063-022-06956-9)
- Lenihan, R. A. F. et al. 2022. Mid-regional pro-adrenomedullin in combination with pediatric early warning scores for risk stratification of febrile children presenting to the emergency department: secondary analysis of a nonprespecified United Kingdom cohort study. Pediatric Critical Care Medicine 23(12), pp. 980-989. (10.1097/PCC.0000000000003075)
- Gwilym, B. L. et al. 2022. Short-term risk prediction after major lower limb amputation: PERCEIVE study. BJS Open 109(12), pp. 1300-1311. (10.1093/bjs/znac309)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients (PEACH): protocol for a retrospective observational study. Methods and Protocols 5(6), article number: 95. (10.3390/mps5060095)
- Euden, J. et al. 2022. PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial. BMJ Open 12(6), article number: e063424. (10.1136/bmjopen-2022-063424)
- Abbott, R. A. et al. 2022. Observational study to estimate the proportion of surgical site infection following excision of ulcerated skin tumours (OASIS study). Clinical and Experimental Dermatology 47(5), pp. 882-888. (10.1111/ced.15037)
- Totty, J. P., Matin, R. N., Wernham, A., Ray, R., Thomas-Jones, E. and Abbott, R. A. 2022. Use of perioperative prophylactic antibiotics following excision of ulcerated skin lesions in the UK: a national, multispeciality survey of clinicians. Clinical and Experimental Dermatology 47(5), pp. 957-959. (10.1111/ced.15075)
- Llewelyn, M. J. et al. 2022. Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data. Journal of Antimicrobial Chemotherapy 77(4), pp. 1189-1196. (10.1093/jac/dkac017)
- Gillespie, D. et al. 2022. Associations with post-consultation health-status in primary care managed acute exacerbation of COPD. International Journal of Chronic Obstructive Pulmonary Disease 2022(17), pp. 383-394. (10.2147/COPD.S340710)
- Allen, D. et al. 2022. Development, implementation and evaluation of an early warning system improvement programme for children in hospital: the PUMA mixed-methods study. Health and Social Care Delivery Research 10(1) (10.3310/CHCK4556)
- Waldron, C. et al. 2022. Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial. BMJ Open 12(1), article number: e047490. (10.1136/bmjopen-2020-047490)
- Milosevic, S. et al. 2022. PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation: a collaboratiVE study (PERCEIVE)—protocol for the PERCEIVE qualitative study. BMJ Open 12(1), article number: e053159. (10.1136/bmjopen-2021-053159)
- Milosevic, S. et al. 2021. Exploring patients’ experiences of analgesia after major lower limb amputation: A qualitative study. BMJ Open 11, article number: e054618. (10.1136/bmjopen-2021-054618)
- Gwilym, B. L. et al. 2021. The PERCEIVE quantitative study: PrEdiction of Risk and Communication of outcome following major lower-limb amputation: protocol for a collaboratiVE study. BJS Open 5(6), article number: zrab118. (10.1093/bjsopen/zrab118)
- Richards, O. et al. 2021. Procalcitonin increase is associated with the development of critical care-acquired infections in COVID-19 ARDS. Antibiotics 10(11), article number: 1425. (10.3390/antibiotics10111425)
- Phillips, R. et al. 2021. Cohort profile: The UK COVID-19 Public Experiences (COPE) prospective longitudinal mixed-methods study of health and well-being during the SARSCoV2 coronavirus pandemic. PLoS ONE 16(10), article number: e0258484. (10.1371/journal.pone.0258484)
- Milosevic, S. et al. 2021. Managing LUTS in primary care: qualitative study of GPs’ and patients’ experiences. British Journal of General Practice 71(710), pp. e685-e692. (10.3399/BJGP.2020.1043)
- Preece, R. et al. 2021. A systematic review and narrative synthesis of risk prediction tools used to estimate mortality, morbidity, and other outcomes following major lower limb amputation. European Journal of Vascular and Endovascular Surgery 62(1), pp. 127-135. (10.1016/j.ejvs.2021.02.038)
- Milosevic, S. et al. 2021. Conducting invasive urodynamics in primary care: Qualitative interview study examining experiences of patients and healthcare professionals. Diagnostic and Prognostic Research 5, article number: 10. (10.1186/s41512-021-00100-y)
- Powell, N. et al. 2021. Use of procalcitonin during the first wave of COVID-19 in the acute NHS hospitals: a retrospective observational study. Antibiotics 10(5), article number: 516. (10.3390/antibiotics10050516)
- Pell, B. et al. 2020. PRImary care Management of lower Urinary tract Symptoms in men: protocol for development and validation of a diagnostic and clinical decision support tool (the PriMUS study). BMJ 10(6), article number: e037634. (10.1136/bmjopen-2020-037634)
- Ambler, G. K., Thomas-Jones, E., Edwards, A. G. K. and Twine, C. P. 2020. Prognostic risk modelling for patients undergoing major lower limb amputation: an analysis of the UK National Vascular Registry. European Journal of Vascular and Endovascular Surgery 59(4), pp. 606-613. (10.1016/j.ejvs.2019.12.006)
- Brookes-Howell, L. et al. 2019. Challenges in managing urinary tract infection and the potential of a point-of-care test guided care in primary care: an international qualitative study. BJGP Open 3(2), article number: 18X101630. (10.3399/bjgpopen18X101630)
- Santer, M. et al. 2018. Adding emollient bath additives to standard eczema management for children with eczema: the BATHE RCT. Health Technology Assessment 22(57) (10.3310/hta22570)
- Francis, N. A. et al. 2018. Oral steroids for hearing loss associated with otitis media with effusion in children aged 2 8 years: the OSTRICH RCT. Health Technology Assessment 22(61) (10.3310/hta22610)
- Bosanquet, D. C. et al. 2018. Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. British Journal of Pain 12(4), pp. 257-258. (10.1177/2049463718800736)
- Stuart, B. et al. 2018. Feasibility of weekly participant-reported data collection in a pragmatic randomised controlled trial in primary care: Experiences from the BATHE trial (Bath Additives for the Treatment of cHildhood Eczema). Trials 19, article number: 582.
- Francis, N. A. et al. 2018. Oral steroids for resolution of otitis media with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial. Lancet 392(10147), pp. 557-568. (10.1016/S0140-6736(18)31490-9)
- Prout, H. C. et al. 2018. Patient understanding and acceptability of an early lung cancer diagnosis trial: a qualitative study. Trials 19, article number: 419. (10.1186/s13063-018-2803-4)
- Gillespie, D., Francis, N. A., Carrol, E. D., Thomas-Jones, E., Butler, C. C. and Hood, K. 2018. Use of co-primary outcomes for trials of antimicrobial stewardship interventions. Lancet Infectious Diseases 18(6), pp. 595-597. (10.1016/S1473-3099(18)30289-5)
- Santer, M. et al. 2018. Emollient bath additives for the treatment of childhood eczema (BATHE): multicentre pragmatic parallel group randomised controlled trial of clinical and cost effectiveness. BMJ 361, article number: k1332. (10.1136/bmj.k1332)
- Butler, C. C. et al. 2018. Point-of-care urine culture for managing urinary tract infection in primary care: a randomised controlled trial of clinical and cost-effectiveness. British Journal of General Practice 68(669), pp. e268-e278. (10.3399/bjgp18X695285)
- Ingram, J. et al. 2018. Levels of wound calprotectin and other inflammatory biomarkers aid in deciding which patients with a diabetic foot ulcer need antibiotic therapy (INDUCE study). Diabetic Medicine 35(2), pp. 255-261. (10.1111/dme.13431)
- Butler, C. C. et al. 2017. Variations in presentation, management, and patient outcomes of urinary tract infection: a prospective four-country primary care observational cohort study. British Journal of General Practice 67(665), pp. e830-e841. (10.3399/bjgp17X693641)
- Ambler, G. K., Bosanquet, D. C., Brookes-Howell, L., Thomas-Jones, R. E., Waldron, C., Edwards, A. G. K. and Twine, C. P. 2017. Development of a core outcome set for studies involving patients undergoing major lower limb amputation for peripheral arterial disease: study protocol for a systematic review and identification of a core outcome set using a Delphi survey. Trials 18(1), article number: 628. (10.1186/s13063-017-2358-9)
- Bosanquet, D. C. et al. 2017. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 18, article number: 629. (10.1186/s13063-017-2357-x)
- Shepherd, V., Thomas-Jones, E., Ridd, M. J., Hood, K., Addison, K. and Francis, N. 2017. Impact of a deferred recruitment model in a randomised controlled trial in primary care (CREAM study). Trials 18(1), article number: 533. (10.1186/s13063-017-2284-x)
- Hollingworth, W. et al. 2017. The diagnosis of urinary tract infection in young children (DUTY) study clinical rule: economic evaluation. Value in Health 20(4), pp. 556-566. (10.1016/j.jval.2017.01.003)
- Francis, N. A. et al. 2017. Oral and topical antibiotics for clinically infected eczema in children: a pragmatic randomized controlled trial in ambulatory care. Annals of Family Medicine 15(2), pp. 124-130. (10.1370/afm.2038)
- Glover, G. W. et al. 2016. Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest - an analysis of the TTM trial data. Critical care (London, England) 20(1), article number: 381. (10.1186/s13054-016-1552-6)
- Francis, N. A. et al. 2016. A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: the ChildRen with Eczema, Antibiotic Management (CREAM) study. Health Technology Assessment 20(19), pp. 1-84. (10.3310/hta20190)
- Waldron, C. et al. 2016. Oral Steroids for the Resolution of Otitis Media with Effusion (OME) in Children (OSTRICH): study protocol for a randomised controlled trial. Trials 17, article number: 115. (10.1186/s13063-016-1236-1)
- Gillespie, D. et al. 2015. Antibiotic prescribing and associated diarrhoea: a prospective cohort study of care home residents. Age and Ageing 44(5), pp. 853-860. (10.1093/ageing/afv072)
- Butler, C. C. et al. 2015. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. British Journal of General Practice 65(633), pp. e217-e223. (10.3399/bjgp15X684361)
- Bates, J. et al. 2014. Point of care testing for urinary tract infection in primary care (POETIC): protocol for a randomised controlled trial of the clinical and cost effectiveness of FLEXICULT (TM) informed management of uncomplicated UTI in primary care. BMC Family Practice 15, pp. -., article number: 187. (10.1186/s12875-014-0187-4)
- Bates, J. et al. 2013. Effects of an optimised POCT guided diagnostic and treatment strategy for symptoms of uncomplicated UTI on use of appropriate antibiotics and uptake into primary care practice. [Abstract]. Trials 14(S1), pp. -., article number: P10. (10.1186/1745-6215-14-S1-P10)
- Waldron, C. et al. 2013. Recruitment to diagnosis of urinary tract infections in young children (DUTY) study: an evaluation of the successful methods used in a primary care, prospective cohort study. [Abstract]. Trials 14(S1), pp. -., article number: P37. (10.1186/1745-6215-14-S1-P37)
- Robling, M. R. et al. 2012. The effect of the Talking Diabetes consulting skills intervention on glycaemic control and quality of life in children with type 1 diabetes: cluster randomised controlled trial (DEPICTED study). British Medical Journal 344, article number: e2359. (10.1136/bmj.e2359)
- Gregory, J. W. et al. 2011. Development and evaluation by a cluster randomised trial of a psychosocial intervention in children and teenagers experiencing diabetes: The DEPICTED study. Health Technology Assessment 15(29), pp. 1-202. (10.3310/hta15290)
Conferences
- Chatoo, S. A., Thomas-Jones, E., Pallmann, P. and Euden, J. 2022. Antibiotic prescribing in hospitalized patients with COVID-19 as a function of inflammatory markers in wave 1 versus wave 2: a systematic review. Presented at: BSAC Spring Conference 2022, 10 - 11 May 2022, Vol. 4. Vol. S.2., (10.1093/jacamr/dlac053.012)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalized patients during the first wave of COVID-19: the PEACH study. Presented at: Infection 2021: BSAC Winter Conference, Virtual, 9-10 December 2021, Vol. 4. Vol. 1., (10.1093/jacamr/dlac004.013)
- Gwilym, B. et al. 2021. PERCEIVE: PrEdiction of Risk and Communication of outcome following major lower limb amputation - a collaboratIVE study. Presented at: National Research Collaborative Meeting 2020 (NRCM 2020), Virtual, 19 November - 10 December 2020, Vol. 5. Vol. Supple. Wiley, (10.1093/bjsopen/zrab032.089)
- Francis, N. A. et al. 2016. A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: the ChildRen with Eczema, Antibiotic Management (CREAM) study. Health Technology Assessment 20(19), pp. 1-84. (10.3310/hta20190)
- Waldron, C. et al. 2016. Oral Steroids for the Resolution of Otitis Media with Effusion (OME) in Children (OSTRICH): study protocol for a randomised controlled trial. Trials 17, article number: 115. (10.1186/s13063-016-1236-1)
- Gillespie, D. et al. 2015. Antibiotic prescribing and associated diarrhoea: a prospective cohort study of care home residents. Age and Ageing 44(5), pp. 853-860. (10.1093/ageing/afv072)
- Butler, C. C. et al. 2015. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. British Journal of General Practice 65(633), pp. e217-e223. (10.3399/bjgp15X684361)
- Robling, M. R. et al. 2012. The effect of the Talking Diabetes consulting skills intervention on glycaemic control and quality of life in children with type 1 diabetes: cluster randomised controlled trial (DEPICTED study). British Medical Journal 344, article number: e2359. (10.1136/bmj.e2359)
- Gregory, J. W. et al. 2011. Development and evaluation by a cluster randomised trial of a psychosocial intervention in children and teenagers experiencing diabetes: The DEPICTED study. Health Technology Assessment 15(29), pp. 1-202. (10.3310/hta15290)
Ymchwil
Diddordebau Ymchwil
- Clefydau, llid ac imiwnedd
- Biofarcwyr a dyfeisiau pwynt gofal
- Gofal Sylfaenol
- Sepsis
- Stiwardiaeth gwrthficrobaidd
Grantiau
2021: AMDDIFFYN CYFLYM: treial clinigol addasol o frechu AZD7442 a SARS-CoV-2 mewn cleifion sydd wedi'u hatal imiwnoimiwnedd sy'n agored iawn i haint â firws SARS-CoV-2 (Prif Ymchwilydd ar gyfer CU ac Arweinydd Astudiaeth CTR) £3.1M
2020: Galwad Adfer Cyflym COVID NIHR - Procalcitonin: Gwerthusiad o ddefnydd gwrthfiotig mewn cleifion ysbyty COVID-19 (Astudiaeth PACH). (Ymchwilydd Principial ar gyfer CU ac arweinydd astudiaeth CTR). £731,859
2020: Sêr Cymru (Welsh Governement) - COPE CYMRU - PROFIADAU CYHOEDDUS COVID-19 yng Nghymru: Astudiaeth hydredol dulliau cymysg o agweddau, credoau ac ymddygiad mewn ymateb i'r pandemig coronafeirws. (Prif Ymchwilydd). £127,871
2020: Ymchwil Iechyd a Gofal Cymru (Ymchwil ar gyfer RfPPB Budd Cleifion a Chyhoeddus) - PrEdiction o Risg a Chyfathrebu outcomE yn dilyn torri aelodau isaf mawr - astudiaeth gydlafuratiVE (PERCEIVE). (Cyd-ymgeisydd). £229,225
2020: Ymchwil Gofal Iechyd Cymru (Cyllid Seilwaith Llywodraeth Cymru) - PRIF GANOLFAN. (Cyd-ymgeisydd). £4.8M
2020: Gwerthuso Effeithiolrwydd a Mecanwaith NIHR (EME) - MR-Pro-adrenomedullin (MR-proADM) a Gwerthusiad ImiwnoArbenigol o hyd gwrthfiotig dan arweiniad procalcitonin mewn Plant â Haint ar gyfer Haenu Effeithiolrwydd (PRECISE). (Arweinydd astudiaeth Cyd-Brif Ymchwilydd ac Arweinydd Astudiaeth CTR). £385,451
2019: Gwerthuso Effeithiolrwydd a Mecanwaith NIHR (EME) - Imiwnoglobwlin mewnwythiennol mewn enseffalitis hunanimiwn mewn Oedolion: Hap-dreial a reolir gan placebo dwbl-ddall (ENCEPH-IG). (Prif Ymchwilydd ar gyfer CU ac arweinydd astudiaeth CTR). £2,734,732.
2019: Asesiad Technoleg Iechyd NIHR (HTA) - Gwerthusiad PROcalcitonin a NEWS ar gyfer adnabod sepsis yn amserol a'r defnydd gorau posibl o wrthfiotigau yn yr Adran Achosion Brys (PRONTO). (Prif Ymchwilydd ar gyfer CU ac arweinydd astudiaeth CTR), £1,964,286.
2019: Asesiad Technoleg Iechyd NIHR (HTA) - Therapi Azithromycin ar gyfer Clefyd Cronig yr Ysgyfaint Cynaeddfedrwydd – Treial AZTEC. (Cyd-ymgeisydd), £2,518,929.
2018: Asesiad Technoleg Iechyd NIHR (HTA) - "Rheoli Hidrandenitis Suppurativa (THESEUS). (Cyd-ymgeisydd ac arweinydd astudiaeth CTR), £629,000
2017: Asesiad Technoleg Iechyd NIHR (HTA) - "Hyd a arweinir gan fiomarciwr o Driniaeth Gwrthfiotig mewn Plant yn yr ysbyty gyda haint bacteriol wedi'i gadarnhau neu a amheuir (BATCH). (Prif Ymchwilydd ac arweinydd astudiaeth CTR), £1.5M
2017: Asesiad Technoleg Iechyd NIHR (HTA) - Rheoli gofal sylfaenol symptomau llwybr wrinol is mewn dynion: Datblygu a dilysu cymorth diagnostig a gwneud penderfyniadau (PRIMUS). (Cyd-ymgeisydd ac arweinydd astudiaeth CTR), £1.6M
2016: Ymchwil Iechyd a Gofal Cymru (RfPPB) - Treial clinigol cam II sy'n archwilio'r defnydd o cathetrau perineural ar ôl torri aelodau isaf mawr mewn oedolion ag ischaemia aelod critigol (PLACEMENT) (Prif Ymchwilydd ac arweinydd astudiaeth CTR), £210,552.
2015: Ymchwil Iechyd a Gofal Cymru. Cyllid seilwaith yr Uned Treialon Clinigol 2015-18. (Cyd-ymgeisydd), £2.9m
2014: NIHR Health Service & Delivery Research (HS&DR) - System Rhybudd Cynnar Pediatrig (PEWS): Defnyddio ac Osgoi Marwolaethau (PUMA). (Cyd-ymgeisydd ac Arweinydd Astudiaeth CTR), £1.9M
2013: Ymchwil Iechyd a Gofal Cymru RfPPB - Cefnogi penderfyniadau rhagnodi gwrthfiotig ar gyfer heintiau wlser traed diabetig: ymchwiliad i gywirdeb diagnostig biofarcwyr llidiol. (Cyd-ymgeisydd ac arweinydd astudio SEWTU), £195,920.
2011: Asesiad Technoleg Iechyd NIHR (HTA) - Steroidau Llafar ar gyfer Datrys otitis cyfryngau gydag effusion (OME) Mewn Plant (OSTRICH) (Cyd-ymgeisydd ac arweinydd astudio SEWTU), £1.3M
Bywgraffiad
Addysg a chymwysterau
- 1997: PhD "Yr amcangyfrif o gyfaint plasma cylchredeg gan ddefnyddio startsh hydroxyethyl wedi'i labelu'n fflwroleuol". Ysgol y Biowyddorau Moleciwlaidd a Meddygol, Prifysgol Cymru, Caerdydd.
- 1993: BSc mewn Biocemeg a Ffisioleg (Cydanrhydedd), Prifysgol Cymru, Coleg Caerdydd.
Trosolwg gyrfa
- 2020 - ymlaen: Dirprwy Gyfarwyddwr Is-adran Heintiau, Llid ac Imiwnedd, yn y Ganolfan Treialon Ymchwil.
- 2019 - ymlaen: Uwch Gymrawd Ymchwil, Canolfan Treialon Ymchwil, Prifysgol Caerdydd.
- 2011 - 2019: Cymrawd Ymchwil (Uwch Reolwr Treial), Canolfan Ymchwil Treialon Prifysgol Caerdydd.
- 2010 – 2011: Cymrawd Ymchwil Dros Dro (Uwch Reolwr Prawf), Uned Dreialon De Ddwyrain Cymru, Prifysgol Caerdydd
- 2009 – 2010: Cydymaith Ymchwil (Rheolwr Treial), Uned Dreialon De-ddwyrain Cymru, Prifysgol Caerdydd.
- 1999 – 2008: Uwch Wyddonydd, Technoleg Golau Moleciwlaidd (GenProbe Inc.), Caerdydd
- 1997 – 1999: Cydymaith Ymchwil, Ysgol y Biowyddorau, Prifysgol Cymru, Caerdydd.
Aelodaethau proffesiynol
- Aelod o'r Gymdeithas Gofal Sylfaenol Academaidd (SAPC).
- Aelod o BSAC
Pwyllgorau ac adolygu
- Adolygydd grant ar gyfer Ymchwil Ymchwil Iechyd a Gofal Cymru ar gyfer Budd Cleifion a Chyhoeddus (RfPPB), Ysgol Ymchwil Gofal Sylfaenol NIHR.
- Adolygydd grant ar gyfer dyfarniadau cyllid MRC Hyder mewn Cysyniad a MRC Agosrwydd at Ddarganfod
- Aelod o Bwyllgor Ymchwil a Datblygu Cwm Taf
- Aelod o Bwyllgor Strategaeth Ymchwil Gofal Sylfaenol HCRW
- Aelod o'r pwyllgor llywio ar gyfer Fforwm Ymchwil Canolfan y De Orllewin
- adolygydd cyfnodolion ar gyfer BMJ, BMJ Open, British Journal of General Practice, Trials, a BMC Series (Clefydau Heintus, Ymarfer Teulu).
Meysydd goruchwyliaeth
Mae gen i ddiddordeb mewn goruchwylio myfyrwyr PhD ym meysydd:
- Biomarciwr dan arweiniad gwneud penderfyniadau gwrthficrobaidd
- ymwrthedd gwrthficrobaidd
- Methodoleg treialon clinigol
