Dr Emma Thomas-Jones

(she/her)

Articles

• Kalra, A., Mackay, O., Thomas‐Jones, E., Solomon, T. and Foscarini‐Craggs, P. 2025. Does the use of intravenous immunoglobulin improve clinical outcomes in adults with autoimmune encephalitis? A systematic review. Brain and Behavior 15(5), article number: e70491. (10.1002/brb3.70491)
• Waldron, C. et al. 2025. Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH): a pragmatic, multicentre, open-label, two-arm, individually randomised, controlled trial. The Lancet Child & Adolescent Health 9(2), pp. 121-130. (10.1016/S2352-4642(24)00306-7)
• Varley, M. et al. 2025. Adaptive clinical trial of AZD7442 and SARS-CoV-2 vaccination in immunosuppressed patients highly vulnerable to infection with SARS-CoV-2 virus (RAPID-PROTECTION): protocol for a multicentre, interventional open-label, randomised controlled trial.. BMJ Open 15(1), article number: e084345. (10.1136/bmjopen-2024-084345)
• Edwards, A. et al. 2025. Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study. Health Technology Assessment 29(1) (10.3310/RGTW5711)
• Milosevic, S. et al. 2024. Rehabilitation experiences following major lower limb amputation due to complications of vascular disease: a UK qualitative study. Disability and Rehabilitation 46(26), pp. 6477-6486. (10.1080/09638288.2024.2329747)
• Barry, T. D., Hester, Y., Pallmann, P., Thomas-Jones, E., Underwood, J., Backx, M. and Barry, S. M. 2024. The role of nurses in national TB control programs: qualitative insights from TB cohort review in Wales. Medical Research Archives 12(12) (10.18103/mra.v12i12.6063)
• Sandoe, J. A. T. et al. 2024. A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19. Journal of Antimicrobial Chemotherapy 79(11), pp. 2792-2800., article number: dkae246. (10.1093/jac/dkae246)
• Webb, E. J. D. et al. 2024. The cost-effectiveness of procalcitonin for guiding antibiotic prescribing in individuals hospitalized with COVID-19: part of the PEACH study. Journal of Antimicrobial Chemotherapy 79(8), pp. 1831-1842., article number: dkae167. (10.1093/jac/dkae167)
• Lowe, J. et al. 2024. Azithromycin therapy for prevention of chronic lung disease of prematurity (AZTEC): a multicentre, double-blind, randomised, placebo-controlled trial. The Lancet Respiratory Medicine 12(8), pp. 608-618. (10.1016/S2213-2600(24)00079-1)
• Clark, A. et al. 2024. Assessing acutely ill children in general practice using the National PEWS and LqSOFA clinical scores: a retrospective cohort study. British Journal of General Practice (10.3399/BJGP.2023.0638)
• Abel, K. et al. 2024. System-wide approaches to antimicrobial therapy and antimicrobial resistance in the UK: the AMR-X framework. The Lancet Microbe 5(5), pp. e500-e507. (10.1016/S2666-5247(24)00003-X)
• Webb, E. J. D. et al. 2024. Evidence of quality of life for hospitalised patients with COVID-19: a scoping review. Health Technology Assessment (10.3310/ATPR4281)
• Ingram, J. R. et al. 2024. Treatment of hidradenitis suppurativa evaluation study (THESEUS): a prospective cohort study. British Journal of Dermatology 190(3), pp. 382-391. (10.1093/bjd/ljad388)
• Gwilym, B. L. et al. 2024. Long-term risk prediction after major lower limb amputation: 1-year results of the PERCEIVE study. BJS Open 8(1), article number: zrad135. (10.1093/bjsopen/zrad135)
• Ingram, J. R. et al. 2023. Treatment of hidradenitis suppurativa evaluation study: the THESEUS prospective cohort study. Health Technology Assessment 27, article number: 30. (10.3310/HWNM2189)
• Henley, J. et al. 2023. Developing a model for decision-making around antibiotic prescribing for patients with COVID-19 pneumonia in acute NHS hospitals during the first wave of the COVID-19 pandemic: Qualitative results from the Procalcitonin Evaluation of Antibiotic use in COVID-19 Hospitalised patients (PEACH Study). BMJ Open 13(12), article number: e077117. (10.1136/bmjopen-2023-077117)
• Leighton, P. et al. 2023. Research priorities in the management of Hidradenitis Suppurativa [Research Letter]. British Journal of Dermatology 189(3), pp. 343-345. (10.1093/bjd/ljad152)
• Schoenbuchner, S. M., Huang, C., Waldron, C., Thomas-Jones, E., Hood, K., Carrol, E. D. and Pallmann, P. 2023. Biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: statistical analysis plan for the BATCH trial and PRECISE sub-study. Trials 24(1), article number: 364. (10.1186/s13063-022-06956-9)
• Lenihan, R. A. F. et al. 2022. Mid-regional pro-adrenomedullin in combination with pediatric early warning scores for risk stratification of febrile children presenting to the emergency department: secondary analysis of a nonprespecified United Kingdom cohort study. Pediatric Critical Care Medicine 23(12), pp. 980-989. (10.1097/PCC.0000000000003075)
• Gwilym, B. L. et al. 2022. Short-term risk prediction after major lower limb amputation: PERCEIVE study. BJS Open 109(12), pp. 1300-1311. (10.1093/bjs/znac309)
• Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients (PEACH): protocol for a retrospective observational study. Methods and Protocols 5(6), article number: 95. (10.3390/mps5060095)
• Euden, J. et al. 2022. PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial. BMJ Open 12(6), article number: e063424. (10.1136/bmjopen-2022-063424)
• Totty, J. P., Matin, R. N., Wernham, A., Ray, R., Thomas-Jones, E. and Abbott, R. A. 2022. Use of perioperative prophylactic antibiotics following excision of ulcerated skin lesions in the UK: a national, multispeciality survey of clinicians. Clinical and Experimental Dermatology 47(5), pp. 957-959. (10.1111/ced.15075)
• Abbott, R. A. et al. 2022. Observational study to estimate the proportion of surgical site infection following excision of ulcerated skin tumours (OASIS study). Clinical and Experimental Dermatology 47(5), pp. 882-888. (10.1111/ced.15037)
• Gillespie, D. et al. 2022. Associations with post-consultation health-status in primary care managed acute exacerbation of COPD. International Journal of Chronic Obstructive Pulmonary Disease 2022(17), pp. 383-394. (10.2147/COPD.S340710)
• Allen, D. et al. 2022. Development, implementation and evaluation of an early warning system improvement programme for children in hospital: the PUMA mixed-methods study. Health and Social Care Delivery Research 10(1) (10.3310/CHCK4556)
• Waldron, C. et al. 2022. Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial. BMJ Open 12(1), article number: e047490. (10.1136/bmjopen-2020-047490)
• Milosevic, S. et al. 2022. PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation: a collaboratiVE study (PERCEIVE)—protocol for the PERCEIVE qualitative study. BMJ Open 12(1), article number: e053159. (10.1136/bmjopen-2021-053159)
• Milosevic, S. et al. 2021. Exploring patients’ experiences of analgesia after major lower limb amputation: A qualitative study. BMJ Open 11, article number: e054618. (10.1136/bmjopen-2021-054618)
• Gwilym, B. L. et al. 2021. The PERCEIVE quantitative study: PrEdiction of Risk and Communication of outcome following major lower-limb amputation: protocol for a collaboratiVE study. BJS Open 5(6), article number: zrab118. (10.1093/bjsopen/zrab118)
• Richards, O. et al. 2021. Procalcitonin increase is associated with the development of critical care-acquired infections in COVID-19 ARDS. Antibiotics 10(11), article number: 1425. (10.3390/antibiotics10111425)
• Phillips, R. et al. 2021. Cohort profile: The UK COVID-19 Public Experiences (COPE) prospective longitudinal mixed-methods study of health and well-being during the SARSCoV2 coronavirus pandemic. PLoS ONE 16(10), article number: e0258484. (10.1371/journal.pone.0258484)
• Milosevic, S. et al. 2021. Managing LUTS in primary care: qualitative study of GPs’ and patients’ experiences. British Journal of General Practice 71(710), pp. e685-e692. (10.3399/BJGP.2020.1043)
• Preece, R. et al. 2021. A systematic review and narrative synthesis of risk prediction tools used to estimate mortality, morbidity, and other outcomes following major lower limb amputation. European Journal of Vascular and Endovascular Surgery 62(1), pp. 127-135. (10.1016/j.ejvs.2021.02.038)
• Milosevic, S. et al. 2021. Conducting invasive urodynamics in primary care: Qualitative interview study examining experiences of patients and healthcare professionals. Diagnostic and Prognostic Research 5, article number: 10. (10.1186/s41512-021-00100-y)
• Powell, N. et al. 2021. Use of procalcitonin during the first wave of COVID-19 in the acute NHS hospitals: a retrospective observational study. Antibiotics 10(5), article number: 516. (10.3390/antibiotics10050516)
• Pell, B. et al. 2020. PRImary care Management of lower Urinary tract Symptoms in men: protocol for development and validation of a diagnostic and clinical decision support tool (the PriMUS study). BMJ 10(6), article number: e037634. (10.1136/bmjopen-2020-037634)
• Ambler, G. K., Thomas-Jones, E., Edwards, A. G. K. and Twine, C. P. 2020. Prognostic risk modelling for patients undergoing major lower limb amputation: an analysis of the UK National Vascular Registry. European Journal of Vascular and Endovascular Surgery 59(4), pp. 606-613. (10.1016/j.ejvs.2019.12.006)
• Brookes-Howell, L. et al. 2019. Challenges in managing urinary tract infection and the potential of a point-of-care test guided care in primary care: an international qualitative study. BJGP Open 3(2), article number: 18X101630. (10.3399/bjgpopen18X101630)
• Francis, N. A. et al. 2018. Oral steroids for hearing loss associated with otitis media with effusion in children aged 2 8 years: the OSTRICH RCT. Health Technology Assessment 22(61) (10.3310/hta22610)
• Santer, M. et al. 2018. Adding emollient bath additives to standard eczema management for children with eczema: the BATHE RCT. Health Technology Assessment 22(57) (10.3310/hta22570)
• Bosanquet, D. C. et al. 2018. Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. British Journal of Pain 12(4), pp. 257-258. (10.1177/2049463718800736)
• Stuart, B. et al. 2018. Feasibility of weekly participant-reported data collection in a pragmatic randomised controlled trial in primary care: Experiences from the BATHE trial (Bath Additives for the Treatment of cHildhood Eczema). Trials 19, article number: 582.
• Francis, N. A. et al. 2018. Oral steroids for resolution of otitis media with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial. Lancet 392(10147), pp. 557-568. (10.1016/S0140-6736(18)31490-9)
• Prout, H. C. et al. 2018. Patient understanding and acceptability of an early lung cancer diagnosis trial: a qualitative study. Trials 19, article number: 419. (10.1186/s13063-018-2803-4)
• Gillespie, D., Francis, N. A., Carrol, E. D., Thomas-Jones, E., Butler, C. C. and Hood, K. 2018. Use of co-primary outcomes for trials of antimicrobial stewardship interventions. Lancet Infectious Diseases 18(6), pp. 595-597. (10.1016/S1473-3099(18)30289-5)
• Santer, M. et al. 2018. Emollient bath additives for the treatment of childhood eczema (BATHE): multicentre pragmatic parallel group randomised controlled trial of clinical and cost effectiveness. BMJ 361, article number: k1332. (10.1136/bmj.k1332)
• Butler, C. C. et al. 2018. Point-of-care urine culture for managing urinary tract infection in primary care: a randomised controlled trial of clinical and cost-effectiveness. British Journal of General Practice 68(669), pp. e268-e278. (10.3399/bjgp18X695285)
• Ingram, J. et al. 2018. Levels of wound calprotectin and other inflammatory biomarkers aid in deciding which patients with a diabetic foot ulcer need antibiotic therapy (INDUCE study). Diabetic Medicine 35(2), pp. 255-261. (10.1111/dme.13431)
• Butler, C. C. et al. 2017. Variations in presentation, management, and patient outcomes of urinary tract infection: a prospective four-country primary care observational cohort study. British Journal of General Practice 67(665), pp. e830-e841. (10.3399/bjgp17X693641)
• Bosanquet, D. C. et al. 2017. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 18, article number: 629. (10.1186/s13063-017-2357-x)
• Ambler, G. K., Bosanquet, D. C., Brookes-Howell, L., Thomas-Jones, R. E., Waldron, C., Edwards, A. G. K. and Twine, C. P. 2017. Development of a core outcome set for studies involving patients undergoing major lower limb amputation for peripheral arterial disease: study protocol for a systematic review and identification of a core outcome set using a Delphi survey. Trials 18(1), article number: 628. (10.1186/s13063-017-2358-9)
• Shepherd, V., Thomas-Jones, E., Ridd, M. J., Hood, K., Addison, K. and Francis, N. 2017. Impact of a deferred recruitment model in a randomised controlled trial in primary care (CREAM study). Trials 18(1), article number: 533. (10.1186/s13063-017-2284-x)
• Hollingworth, W. et al. 2017. The diagnosis of urinary tract infection in young children (DUTY) study clinical rule: economic evaluation. Value in Health 20(4), pp. 556-566. (10.1016/j.jval.2017.01.003)
• Francis, N. A. et al. 2017. Oral and topical antibiotics for clinically infected eczema in children: a pragmatic randomized controlled trial in ambulatory care. Annals of Family Medicine 15(2), pp. 124-130. (10.1370/afm.2038)
• Glover, G. W. et al. 2016. Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest - an analysis of the TTM trial data. Critical care (London, England) 20(1), article number: 381. (10.1186/s13054-016-1552-6)
• Francis, N. A. et al. 2016. A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: the ChildRen with Eczema, Antibiotic Management (CREAM) study. Health Technology Assessment 20(19), pp. 1-84. (10.3310/hta20190)
• Waldron, C. et al. 2016. Oral Steroids for the Resolution of Otitis Media with Effusion (OME) in Children (OSTRICH): study protocol for a randomised controlled trial. Trials 17, article number: 115. (10.1186/s13063-016-1236-1)
• Gillespie, D. et al. 2015. Antibiotic prescribing and associated diarrhoea: a prospective cohort study of care home residents. Age and Ageing 44(5), pp. 853-860. (10.1093/ageing/afv072)
• Butler, C. C. et al. 2015. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. British Journal of General Practice 65(633), pp. e217-e223. (10.3399/bjgp15X684361)
• Bates, J. et al. 2014. Point of care testing for urinary tract infection in primary care (POETIC): protocol for a randomised controlled trial of the clinical and cost effectiveness of FLEXICULT (TM) informed management of uncomplicated UTI in primary care. BMC Family Practice 15, pp. -., article number: 187. (10.1186/s12875-014-0187-4)
• Bates, J. et al. 2013. Effects of an optimised POCT guided diagnostic and treatment strategy for symptoms of uncomplicated UTI on use of appropriate antibiotics and uptake into primary care practice. [Abstract]. Trials 14(S1), pp. -., article number: P10. (10.1186/1745-6215-14-S1-P10)
• Waldron, C. et al. 2013. Recruitment to diagnosis of urinary tract infections in young children (DUTY) study: an evaluation of the successful methods used in a primary care, prospective cohort study. [Abstract]. Trials 14(S1), pp. -., article number: P37. (10.1186/1745-6215-14-S1-P37)
• Robling, M. R. et al. 2012. The effect of the Talking Diabetes consulting skills intervention on glycaemic control and quality of life in children with type 1 diabetes: cluster randomised controlled trial (DEPICTED study). British Medical Journal 344, article number: e2359. (10.1136/bmj.e2359)
• Gregory, J. W. et al. 2011. Development and evaluation by a cluster randomised trial of a psychosocial intervention in children and teenagers experiencing diabetes: The DEPICTED study. Health Technology Assessment 15(29), pp. 1-202. (10.3310/hta15290)

Conferences

• Chatoo, S. A., Thomas-Jones, E., Pallmann, P. and Euden, J. 2022. Antibiotic prescribing in hospitalized patients with COVID-19 as a function of inflammatory markers in wave 1 versus wave 2: a systematic review. Presented at: BSAC Spring Conference 2022, 10 - 11 May 2022, Vol. 4. Vol. S.2., (10.1093/jacamr/dlac053.012)
• Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalized patients during the first wave of COVID-19: the PEACH study. Presented at: Infection 2021: BSAC Winter Conference, Virtual, 9-10 December 2021, Vol. 4. Vol. 1., (10.1093/jacamr/dlac004.013)
• Gwilym, B. et al. 2021. PERCEIVE: PrEdiction of Risk and Communication of outcome following major lower limb amputation - a collaboratIVE study. Presented at: National Research Collaborative Meeting 2020 (NRCM 2020), Virtual, 19 November - 10 December 2020, Vol. 5. Vol. Supple. Wiley, (10.1093/bjsopen/zrab032.089)

• Francis, N. A. et al. 2016. A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: the ChildRen with Eczema, Antibiotic Management (CREAM) study. Health Technology Assessment 20(19), pp. 1-84. (10.3310/hta20190)
• Waldron, C. et al. 2016. Oral Steroids for the Resolution of Otitis Media with Effusion (OME) in Children (OSTRICH): study protocol for a randomised controlled trial. Trials 17, article number: 115. (10.1186/s13063-016-1236-1)
• Gillespie, D. et al. 2015. Antibiotic prescribing and associated diarrhoea: a prospective cohort study of care home residents. Age and Ageing 44(5), pp. 853-860. (10.1093/ageing/afv072)
• Butler, C. C. et al. 2015. Childhood urinary tract infection in primary care: a prospective observational study of prevalence, diagnosis, treatment, and recovery. British Journal of General Practice 65(633), pp. e217-e223. (10.3399/bjgp15X684361)
• Robling, M. R. et al. 2012. The effect of the Talking Diabetes consulting skills intervention on glycaemic control and quality of life in children with type 1 diabetes: cluster randomised controlled trial (DEPICTED study). British Medical Journal 344, article number: e2359. (10.1136/bmj.e2359)
• Gregory, J. W. et al. 2011. Development and evaluation by a cluster randomised trial of a psychosocial intervention in children and teenagers experiencing diabetes: The DEPICTED study. Health Technology Assessment 15(29), pp. 1-202. (10.3310/hta15290)