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Dr Christopher Thomas
Lecturer
Trosolwyg
Cwblheais fy ngradd mewn Cemeg gyda Phrofiad Diwydiannol yn 2002 o Brifysgol Caerdydd cyn symud i'r Ysgol Fferylliaeth i ymgymryd â PhD mewn darpariaeth drawsdermol. Yn dilyn hyn, cwblheais swydd ôl-ddoethurol yn Ysgol Meddygaeth Prifysgol Caerdydd cyn derbyn Cymrodoriaeth Marie Curie yn 2010 i astudio yn Ysgol Meddygaeth Prifysgol Vanderbilt, Nashville, TN. Yn 2013 enillais gymrodoriaeth NISHCR/Wellcome Trust cyn gweithredu fel cyd-ymchwilydd a Chymrawd Ymchwil ar Wobr Ymchwil MRC. Dechreuais fy swydd bresennol fel Darlithydd yn yr Ysgol Fferylliaeth a Gwyddorau Fferyllol ym mis Tachwedd 2016.
Cyhoeddiad
2024
- Correia, B., Pontes, J. G., Torrinhas, R. S., Val, A. L., Thomas, C. P. and Tasic, L. 2024. Evaluation of the Amazon River seasonal influences on Glycerophospholipids in wild fish. Journal of the Brazilian Chemical Society 35(7), article number: e-20240015. (10.21577/0103-5053.20240015)
2023
- O’Donnell, V. B. et al. 2023. Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples. Nature Communications 14(1), article number: 7172. (10.1038/s41467-023-41766-w)
- Moukachar, A. et al. 2023. Development and evaluation of a low‐cost lego 3d bioprinter: from building‐blocks to building blocks of life. Advanced Materials Technologies 8(6), article number: 2100868. (10.1002/admt.202100868)
2021
- Tyrrell, V. J. et al. 2021. Lipidomic and transcriptional analysis of the Linoleoyl-omega-Hydroxyceramide biosynthetic pathway in human psoriatic lesions. Journal of Lipid Research 62, article number: 100094. (10.1016/j.jlr.2021.100094)
2020
- Rosas, M. et al. 2020. The procoagulant activity of tissue factor expressed on fibroblasts is increased by tissue factor-negative extracellular vesicles. PLoS ONE 15(10), article number: e0240189. (10.1371/journal.pone.0240189)
2018
- King, H., Cosslett, A. G., Thomas, C. P. and Price-Davies, R. 2018. A HPLC method to monitor the occurrence of lipid peroxidation in intravenous lipid emulsions used in parenteral nutrition using in-line UV and charged aerosol detection. Clinical Nutrition ESPEN 28, pp. 96-102. (10.1016/j.clnesp.2018.09.005)
2017
- Lauder, S. N. et al. 2017. Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis. Science Signaling 10(507), article number: eaan2787. (10.1126/scisignal.aan2787)
2016
- Chiba, T., Thomas, C. P., Calcutt, M. W., Boeglin, W. E., O'Donnell, V. B. and Brash, A. R. 2016. The precise structures and stereochemistry of trihydroxy-linoleates esterified in human and porcine epidermis and their significance in skin barrier function: Implication of an epoxide hydrolase in the transformations of linoleate. Journal of Biological Chemistry 291(28), pp. 14540-14544. (10.1074/jbc.M115.711267)
- Hinz, C. et al. 2016. Human platelets utilize cycloxygenase-1 to generate dioxolane A3, a neutrophil activating eicosanoid. Journal of Biological Chemistry 291(26), pp. 13448-13464. (10.1074/jbc.M115.700609)
2015
- McCully, M. L., Collins, P. J., Hughes, T. R., Thomas, C. P., Billen, J., O'Donnell, V. B. and Moser, B. 2015. Skin metabolites define a new paradigm in the localization of skin tropic memory T cells. Journal of Immunology 195(1), pp. 96-104. (10.4049/jimmunol.1402961)
- Morgan, A. H. et al. 2015. A novel role for 12/15-lipoxygenase in regulating autophagy. Redox Biology 4, pp. 40-47. (10.1016/j.redox.2014.11.005)
2014
- Muñoz-Garcia, A., Thomas, C. P., Keeney, D. S., Zheng, Y. and Brash, A. R. 2014. The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1841(3), pp. 401-408. (10.1016/j.bbalip.2013.08.020)
- Thomas, C. P., Clark, S. R., Hammond, V. J., Aldrovandi, M., Collins, P. W. and O'Donnell, V. B. 2014. Identification and quantification of aminophospholipid molecular species on the surface of apoptotic and activated cells. Nature Protocols 9(1), pp. 51-63. (10.1038/nprot.2013.163)
2013
- Clark, S. R. et al. 2013. Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation. Proceedings of the National Academy of Sciences of the United States of America 110(15), pp. 5875-5880. (10.1073/pnas.1222419110)
- Moideen, A. N. et al. 2013. Characterization of enzymes involved in nicotinamide adenine dinucleotide biosynthesis in rheumatoid arthritis synovium and cytokine-stimulated synovial fibroblasts [Abstracts]. Rhuematology 52(s1), pp. 138-139.
- Thomas, C. P., Boeglin, W. E., Garcia-Diaz, Y., O'Donnell, V. B. and Brash, A. R. 2013. Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis. Chemistry and Physics of Lipids 167, pp. 21-32. (10.1016/j.chemphyslip.2013.01.002)
2012
- Hammond, V. J. et al. 2012. Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ. Journal of Biological Chemistry 287(50), pp. 41651-41666. (10.1074/jbc.M112.405407)
- Thomas, C. P. and O'Donnell, V. B. 2012. Oxidized phospholipid signaling in immune cells. Current Opinion in Pharmacology 12(4), pp. 471-477. (10.1016/j.coph.2012.02.013)
2011
- Ruge, F. et al. 2011. Delineating immune-mediated mechanisms underlying hair follicle destruction in the mouse mutant defolliculated. Journal of Investigative Dermatology 131(3), pp. 572-579. (10.1038/jid.2010.379)
- Zulfakar, M. H., Alex, A., Povazay, B., Drexler, W., Thomas, C. P., Porter, R. M. and Heard, C. M. 2011. In vivo response of GsdmA3Dfl/+ mice to topically applied anti-psoriatic agents: effects on epidermal thickness, as determined by optical coherence tomography and H&E staining. Experimental Dermatology 20(3), pp. 269-272. (10.1111/j.1600-0625.2010.01233.x)
- Trostchansky, A., Bonilla, L., Thomas, C. P., O'Donnell, V. B., Marnett, L. J., Radi, R. and Rubbo, H. 2011. Nitroarachidonic Acid, a Novel Peroxidase Inhibitor of Prostaglandin Endoperoxide H Synthases 1 and 2. Journal of Biological Chemistry 286(15), pp. 12891-12900. (10.1074/jbc.M110.154518)
- Clark, S. R. et al. 2011. Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection. Blood 117(6), pp. 2033-2043. (10.1182/blood-2010-04-278887)
2010
- Thomas, C. P. et al. 2010. Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. Journal of Biological Chemistry 285(10), pp. 6891-6903. (10.1074/jbc.M109.078428)
- Morgan, A. H. et al. 2010. Quantitative assays for esterified oxylipins generated by immune cells. Nature Protocols 5(12), pp. 1919-1931. (10.1038/nprot.2010.162)
- Morgan, L. T., Thomas, C. P., Kühn, H. and O'Donnell, V. B. 2010. Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase. Biochemical Journal 431(1), pp. 141-148. (10.1042/BJ20100415)
2009
- Morgan, A. H. et al. 2009. Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease. Journal of Biological Chemistry 284(32), pp. 21185-21191. (10.1074/jbc.M109.021634)
- Gregory, L. G. et al. 2009. Inhaled house dust mite induces pulmonary T helper 2 cytokine production. Clinical and Experimental Allergy 39(10), pp. 1597-1610. (10.1111/j.1365-2222.2009.03302.x)
2007
- Heard, C. M. and Thomas, C. P. 2007. Probing the skin permeation of eicosapentaenoic acid and ketoprofen 2. Comparative depth profiling and metabolism of eicosapentaenoic acid. European Journal of Pharmaceutics and Biopharmaceutics 67(1), pp. 156-165. (10.1016/j.ejpb.2006.11.024)
- Thomas, C. P., Davison, Z. and Heard, C. M. 2007. Probing the skin permeation of fish oil/EPA and ketoprofen-3. Effects on epidermal COX-2 and LOX. Prostaglandins Leukotrienes & Essential Fatty Acids 76(6), pp. 357-362. (10.1016/j.plefa.2007.05.002)
- Thomas, C. P. and Heard, C. M. 2007. Probing the skin permeation of eicosapentaenoic acid and ketoprofen - 2. Comparative depth profiling and metabolism of eicosapentaenoic acid. European Journal of Pharmaceutics and Biopharmaceutics 67(1), pp. 156-165. (10.1016/j.ejpb.2006.11.024)
- Thomas, C. P., Platts, J. A., Tatchell, T. and Heard, C. M. 2007. Probing the skin permeation of fish oil/EPA and ketoprofen 1. NMR spectroscopy and molecular modelling. International Journal of Pharmaceutics 338(1-2), pp. 207-212. (10.1016/j.ijpharm.2007.02.006)
2006
- Heard, C. M., Kung, D. and Thomas, C. P. 2006. Skin penetration enhancement of mefenamic acid by ethanol and 1,8-cineole can be explained by the ‘pull’ effect. International Journal of Pharmaceutics 321(1-2), pp. 167-170. (10.1016/j.ijpharm.2006.05.018)
- Thomas, C. P. 2006. Transcutaneous delivery of anti-arthritic agents.. PhD Thesis, Cardiff University.
- Heard, C. M., Johnson, S., Moss, G. and Thomas, C. P. 2006. In vitro transdermal delivery of caffeine, theobromine, theophylline and catechin from extract of Guarana, Paullinia Cupana. International Journal of Pharmaceutics 317(1), pp. 26-31. (10.1016/j.ijpharm.2006.02.042)
- Richards, H., Thomas, C. P., Bowen, J. L. and Heard, C. M. 2006. In-vitro transcutaneous delivery of ketoprofen and polyunsaturated fatty acids from a pluronic lecithin organogel vehicle containing fish oil. African Journal of Pharmacy and Pharmacology 58(7), pp. 903-908. (10.1211/jpp.58.7.0004)
2005
- Heard, C. M. et al. 2005. Preferential π–π complexation between tamoxifen and borage oil/γ linolenic acid: transcutaneous delivery and NMR spectral modulation. International Journal of Pharmaceutics 302(1-2), pp. 47-55. (10.1016/j.ijpharm.2005.06.013)
- Thomas, C. P. and Heard, C. M. 2005. In vitro transcutaneous delivery of ketoprofen and essential polyunsaturated fatty acids from a fish oil vehicle incorporating 1,8-cineole. Drug Delivery 12(1), pp. 7-14. (10.1080/10717540590889565)
2004
- Ho, S., Calder, R. J., Thomas, C. P. and Heard, C. M. 2004. In-vitro transcutaneous delivery of tamoxifen and γ-linolenic acid from borage oil containing ethanol and 1,8-cineole. Pharmacy and Pharmacology 56(11), pp. 1357-1364. (10.1211/0022357044599)
- Batchelder, R. J., Calder, R. J., Thomas, C. P. and Heard, C. M. 2004. In vitro transdermal delivery of the major catechins and caffeine from extract of Camellia sinensis. International Journal of Pharmaceutics 283(1-2), pp. 45-51. (10.1016/j.ijpharm.2004.06.007)
2001
- Davidge, J., Thomas, C. P. and Williams, D. R. 2001. Conditional formation constants or chemical speciation data?. Chemical Speciation and Bioavailability 13(4), pp. 129-134. (10.3184/095422901782775390)
Articles
- Correia, B., Pontes, J. G., Torrinhas, R. S., Val, A. L., Thomas, C. P. and Tasic, L. 2024. Evaluation of the Amazon River seasonal influences on Glycerophospholipids in wild fish. Journal of the Brazilian Chemical Society 35(7), article number: e-20240015. (10.21577/0103-5053.20240015)
- O’Donnell, V. B. et al. 2023. Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples. Nature Communications 14(1), article number: 7172. (10.1038/s41467-023-41766-w)
- Moukachar, A. et al. 2023. Development and evaluation of a low‐cost lego 3d bioprinter: from building‐blocks to building blocks of life. Advanced Materials Technologies 8(6), article number: 2100868. (10.1002/admt.202100868)
- Tyrrell, V. J. et al. 2021. Lipidomic and transcriptional analysis of the Linoleoyl-omega-Hydroxyceramide biosynthetic pathway in human psoriatic lesions. Journal of Lipid Research 62, article number: 100094. (10.1016/j.jlr.2021.100094)
- Rosas, M. et al. 2020. The procoagulant activity of tissue factor expressed on fibroblasts is increased by tissue factor-negative extracellular vesicles. PLoS ONE 15(10), article number: e0240189. (10.1371/journal.pone.0240189)
- King, H., Cosslett, A. G., Thomas, C. P. and Price-Davies, R. 2018. A HPLC method to monitor the occurrence of lipid peroxidation in intravenous lipid emulsions used in parenteral nutrition using in-line UV and charged aerosol detection. Clinical Nutrition ESPEN 28, pp. 96-102. (10.1016/j.clnesp.2018.09.005)
- Lauder, S. N. et al. 2017. Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis. Science Signaling 10(507), article number: eaan2787. (10.1126/scisignal.aan2787)
- Chiba, T., Thomas, C. P., Calcutt, M. W., Boeglin, W. E., O'Donnell, V. B. and Brash, A. R. 2016. The precise structures and stereochemistry of trihydroxy-linoleates esterified in human and porcine epidermis and their significance in skin barrier function: Implication of an epoxide hydrolase in the transformations of linoleate. Journal of Biological Chemistry 291(28), pp. 14540-14544. (10.1074/jbc.M115.711267)
- Hinz, C. et al. 2016. Human platelets utilize cycloxygenase-1 to generate dioxolane A3, a neutrophil activating eicosanoid. Journal of Biological Chemistry 291(26), pp. 13448-13464. (10.1074/jbc.M115.700609)
- McCully, M. L., Collins, P. J., Hughes, T. R., Thomas, C. P., Billen, J., O'Donnell, V. B. and Moser, B. 2015. Skin metabolites define a new paradigm in the localization of skin tropic memory T cells. Journal of Immunology 195(1), pp. 96-104. (10.4049/jimmunol.1402961)
- Morgan, A. H. et al. 2015. A novel role for 12/15-lipoxygenase in regulating autophagy. Redox Biology 4, pp. 40-47. (10.1016/j.redox.2014.11.005)
- Muñoz-Garcia, A., Thomas, C. P., Keeney, D. S., Zheng, Y. and Brash, A. R. 2014. The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1841(3), pp. 401-408. (10.1016/j.bbalip.2013.08.020)
- Thomas, C. P., Clark, S. R., Hammond, V. J., Aldrovandi, M., Collins, P. W. and O'Donnell, V. B. 2014. Identification and quantification of aminophospholipid molecular species on the surface of apoptotic and activated cells. Nature Protocols 9(1), pp. 51-63. (10.1038/nprot.2013.163)
- Clark, S. R. et al. 2013. Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation. Proceedings of the National Academy of Sciences of the United States of America 110(15), pp. 5875-5880. (10.1073/pnas.1222419110)
- Moideen, A. N. et al. 2013. Characterization of enzymes involved in nicotinamide adenine dinucleotide biosynthesis in rheumatoid arthritis synovium and cytokine-stimulated synovial fibroblasts [Abstracts]. Rhuematology 52(s1), pp. 138-139.
- Thomas, C. P., Boeglin, W. E., Garcia-Diaz, Y., O'Donnell, V. B. and Brash, A. R. 2013. Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis. Chemistry and Physics of Lipids 167, pp. 21-32. (10.1016/j.chemphyslip.2013.01.002)
- Hammond, V. J. et al. 2012. Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ. Journal of Biological Chemistry 287(50), pp. 41651-41666. (10.1074/jbc.M112.405407)
- Thomas, C. P. and O'Donnell, V. B. 2012. Oxidized phospholipid signaling in immune cells. Current Opinion in Pharmacology 12(4), pp. 471-477. (10.1016/j.coph.2012.02.013)
- Ruge, F. et al. 2011. Delineating immune-mediated mechanisms underlying hair follicle destruction in the mouse mutant defolliculated. Journal of Investigative Dermatology 131(3), pp. 572-579. (10.1038/jid.2010.379)
- Zulfakar, M. H., Alex, A., Povazay, B., Drexler, W., Thomas, C. P., Porter, R. M. and Heard, C. M. 2011. In vivo response of GsdmA3Dfl/+ mice to topically applied anti-psoriatic agents: effects on epidermal thickness, as determined by optical coherence tomography and H&E staining. Experimental Dermatology 20(3), pp. 269-272. (10.1111/j.1600-0625.2010.01233.x)
- Trostchansky, A., Bonilla, L., Thomas, C. P., O'Donnell, V. B., Marnett, L. J., Radi, R. and Rubbo, H. 2011. Nitroarachidonic Acid, a Novel Peroxidase Inhibitor of Prostaglandin Endoperoxide H Synthases 1 and 2. Journal of Biological Chemistry 286(15), pp. 12891-12900. (10.1074/jbc.M110.154518)
- Clark, S. R. et al. 2011. Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection. Blood 117(6), pp. 2033-2043. (10.1182/blood-2010-04-278887)
- Thomas, C. P. et al. 2010. Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. Journal of Biological Chemistry 285(10), pp. 6891-6903. (10.1074/jbc.M109.078428)
- Morgan, A. H. et al. 2010. Quantitative assays for esterified oxylipins generated by immune cells. Nature Protocols 5(12), pp. 1919-1931. (10.1038/nprot.2010.162)
- Morgan, L. T., Thomas, C. P., Kühn, H. and O'Donnell, V. B. 2010. Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase. Biochemical Journal 431(1), pp. 141-148. (10.1042/BJ20100415)
- Morgan, A. H. et al. 2009. Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease. Journal of Biological Chemistry 284(32), pp. 21185-21191. (10.1074/jbc.M109.021634)
- Gregory, L. G. et al. 2009. Inhaled house dust mite induces pulmonary T helper 2 cytokine production. Clinical and Experimental Allergy 39(10), pp. 1597-1610. (10.1111/j.1365-2222.2009.03302.x)
- Heard, C. M. and Thomas, C. P. 2007. Probing the skin permeation of eicosapentaenoic acid and ketoprofen 2. Comparative depth profiling and metabolism of eicosapentaenoic acid. European Journal of Pharmaceutics and Biopharmaceutics 67(1), pp. 156-165. (10.1016/j.ejpb.2006.11.024)
- Thomas, C. P., Davison, Z. and Heard, C. M. 2007. Probing the skin permeation of fish oil/EPA and ketoprofen-3. Effects on epidermal COX-2 and LOX. Prostaglandins Leukotrienes & Essential Fatty Acids 76(6), pp. 357-362. (10.1016/j.plefa.2007.05.002)
- Thomas, C. P. and Heard, C. M. 2007. Probing the skin permeation of eicosapentaenoic acid and ketoprofen - 2. Comparative depth profiling and metabolism of eicosapentaenoic acid. European Journal of Pharmaceutics and Biopharmaceutics 67(1), pp. 156-165. (10.1016/j.ejpb.2006.11.024)
- Thomas, C. P., Platts, J. A., Tatchell, T. and Heard, C. M. 2007. Probing the skin permeation of fish oil/EPA and ketoprofen 1. NMR spectroscopy and molecular modelling. International Journal of Pharmaceutics 338(1-2), pp. 207-212. (10.1016/j.ijpharm.2007.02.006)
- Heard, C. M., Kung, D. and Thomas, C. P. 2006. Skin penetration enhancement of mefenamic acid by ethanol and 1,8-cineole can be explained by the ‘pull’ effect. International Journal of Pharmaceutics 321(1-2), pp. 167-170. (10.1016/j.ijpharm.2006.05.018)
- Heard, C. M., Johnson, S., Moss, G. and Thomas, C. P. 2006. In vitro transdermal delivery of caffeine, theobromine, theophylline and catechin from extract of Guarana, Paullinia Cupana. International Journal of Pharmaceutics 317(1), pp. 26-31. (10.1016/j.ijpharm.2006.02.042)
- Richards, H., Thomas, C. P., Bowen, J. L. and Heard, C. M. 2006. In-vitro transcutaneous delivery of ketoprofen and polyunsaturated fatty acids from a pluronic lecithin organogel vehicle containing fish oil. African Journal of Pharmacy and Pharmacology 58(7), pp. 903-908. (10.1211/jpp.58.7.0004)
- Heard, C. M. et al. 2005. Preferential π–π complexation between tamoxifen and borage oil/γ linolenic acid: transcutaneous delivery and NMR spectral modulation. International Journal of Pharmaceutics 302(1-2), pp. 47-55. (10.1016/j.ijpharm.2005.06.013)
- Thomas, C. P. and Heard, C. M. 2005. In vitro transcutaneous delivery of ketoprofen and essential polyunsaturated fatty acids from a fish oil vehicle incorporating 1,8-cineole. Drug Delivery 12(1), pp. 7-14. (10.1080/10717540590889565)
- Ho, S., Calder, R. J., Thomas, C. P. and Heard, C. M. 2004. In-vitro transcutaneous delivery of tamoxifen and γ-linolenic acid from borage oil containing ethanol and 1,8-cineole. Pharmacy and Pharmacology 56(11), pp. 1357-1364. (10.1211/0022357044599)
- Batchelder, R. J., Calder, R. J., Thomas, C. P. and Heard, C. M. 2004. In vitro transdermal delivery of the major catechins and caffeine from extract of Camellia sinensis. International Journal of Pharmaceutics 283(1-2), pp. 45-51. (10.1016/j.ijpharm.2004.06.007)
- Davidge, J., Thomas, C. P. and Williams, D. R. 2001. Conditional formation constants or chemical speciation data?. Chemical Speciation and Bioavailability 13(4), pp. 129-134. (10.3184/095422901782775390)
Thesis
- Thomas, C. P. 2006. Transcutaneous delivery of anti-arthritic agents.. PhD Thesis, Cardiff University.
Ymchwil
Chris's research is focused on the role of oxidised lipids in health and disease. Recent advances in analytical techniques have significantly expanded the knowledge on lipids and they are no longer considered as merely cell membrane constituents. They can now be considered as bioactive mediators involved in a range of cellular and physiological processes from blood clotting and immune cell response to maintaining our skins barrier function.
Chris is currently focused on the role of these lipids in wound healing and skin disease, with particular interest in the crosstalk between skin cells and bacteria that make up the skins microbiome. In collaboration with other members of the School of Pharmacy and Pharmaceutical Sciences, Chris is developing novel skin models using 3D printing to study skin disease and the immunological control of skin cancer progression.
Addysgu
Blwyddyn 1 - Systemau Corff Dynol
Arweinydd y Modiwl
Addysgu - Systemau Cynhwysedd, Sgerbwd a GI
