Professor David Barrow
- Available for postgraduate supervision
Teams and roles for David Barrow
Emeritus Professor
Overview
As a Professor Emeritus, David Barrow’s current interdisciplinary research explores relationships between scientific enquiry, material practice, and perception, developed through the concept of Intersentient States. This work examines how matter, form, and awareness co-emerge within acts of making, drawing on principles of material intelligence, emergence, and embodied cognition. Building on a scientific career in microfluidics and synthetic biology, Barrow’s practice now translates those investigative methods into the language of clay, form, and surface. Through ceramic vessels and sculpted heads, he explores the conditions under which material objects appear to hold presence or reciprocal awareness. His writing on Intersentient States situates these works within contemporary dialogues between art, philosophy, and post-humanist thought. Examples of recent ceramic and sculptural work can be seen at www.davidbarrowstudio.com. He is currently a panel judge for the UK Blavatnik Awards for Young Scientists.
His previous career episodes, embraced both artistic practice and scientific enquiry. The latter has been diverse but settled on synthetic biology from 2010 onwards. He researched compartmentalised, microscale constructs, using microfluidics for their formation, directed towards protocells, proto-tissue and artificial life. He was a partner in the European Union funded Research consortia projects entitled "Artificial Cells with Distributed Cores (ACDC)", and the EIC project, entitled "Bio-Hybrid Hierarchical Organoid-Synthetic Tissues (BiohHOST)" under EU flagship research programme - "Engineered Living Materials".
David Barrow has researched a diversity of microfluidic based phenomena and devices, including chemical sensors, porous silicon, microacoustics, hybrid integration, micromolding, transdermal microneedles, emulsion, droplet and digital microfluidics, chemicals separations, plasma etching, CFD, microwave sensors, laser micromachining and marine microanalysis systems. He was a founder of the UK metaFAB TSB open-access NanoCentre providing bespoke laser micromachining, MSTB Ltd. researching space microsystems, Protasis Corporation developing microdevices for chemicals separations, Q-CHIP Ltd. (merged with Midatech floted on AIM and NASDAQ listed) developing injectable microencapsulated pharmaceuticals, and the Cardiff Da Vinci Innovation Awards. He has flown acoustics experiments on the European Space Agency Zero Gravity laboratory over the Bay of Biscay and was a member of the Cardiff Arctic Norway Expedition studying plate tectonic movements.
Previous to this episode of scientific exploration and entrepreneurship, Barrow was a self-taught exhibiting, ceramicists for several years.
Publication
2024
- Dimitriou, P. et al. 2024. Manipulation of encapsulated artificial phospholipid membranes using sub-micellar lysolipid concentrations. Communications Chemistry 7 (1) 120. (10.1038/s42004-024-01209-z)
- Schneider, J. J. et al., 2024. Percolation breakdown in binary and ternary monodisperse and polydisperse systems of spherical particles. Presented at: Italian Workshop on Artificial Life and Evolutionary Computation Venice 6-8 September 2023. Published in: Villani, M. , Cagnoni, S. and Serra, R. eds. Artificial Life and Evolutionary Computation. WIVACE 2023. Vol. 1977.Communications in Computer and Information Science Cham, Switzerland: Springer. , pp.161-174. (10.1007/978-3-031-57430-6_13)
- Schneider, J. J. et al., 2024. Kauffman Model with spatially separated ligation and cleavage reactions. Presented at: Italian Workshop on Artificial Life and Evolutionary Computation Venice 6-8 September 2023. Published in: Villani, M. , Cagnoni, S. and Serra, R. eds. Artificial Life and Evolutionary Computation. WIVACE 2023. Vol. 1977.Communications in Computer and Information Science Cham, Switzerland: Springer. , pp.141-160. (10.1007/978-3-031-57430-6_12)
- Silver, K. L. et al. 2024. 3D-printed microfluidic-microwave device for droplet network formation and characterisation. Lab on a Chip 24 , pp.5101-5112. (10.1039/D4LC00387J)
2023
- Matuttis, H. et al., 2023. Computational investigation of the clustering of droplets in widening pipe geometries. Presented at: WIVACE 2022, XVI International Workshop on Artificial Life and Evolutionary Computation Gaeta, Italy 14-16 September 2022. Published in: De Stefano, C. , Fontanella, F. and Vanneschi, L. eds. WIVACE 2022. Artificial Life and Evolutionary Computation. Vol. 1780.Communications in Computer and Information Science Cham, Switzerland: Springer. , pp.82-93. (10.1007/978-3-031-31183-3_7)
- Schneider, J. J. et al., 2023. Geometric restrictions to the agglomeration of spherical particles. Presented at: Artificial Life and Evolutionary Computation 15th Italian Workshop, WIVACE 2021, Winterthur, Switzerland, Winterthur, Switzerland 15-17 September 2021. Artificial Life and Evolutionary Computation 15th Italian Workshop, WIVACE 2021, Winterthur, Switzerland, September 15–17, 2021, Revised Selected Papers. Vol. 1722.Springer. , pp.72-84. (10.1007/978-3-031-23929-8_7)
- Schneider, J. J. et al., 2023. Network creation during agglomeration processes of polydisperse and monodisperse systems of droplets. Communications in Computer and Information Science 1780 , pp.94-106. (10.1007/978-3-031-31183-3_8)
- Schneider, J. J. et al., 2023. Artificial chemistry performed in an agglomeration of droplets with restricted molecule transfer. Presented at: WIVACE 2022, XVI International Workshop on Artificial Life and Evolutionary Computation Gaeta, Italy 14-16 September 2022. Published in: De Stefano, C. , Fontanella, F. and Vanneschi, L. eds. WIVACE 2022. Artificial Life and Evolutionary Computation.. Vol. 1780.Communications in Computer and Information Science Cham, Switzerland: Springer. , pp.107-118. (10.1007/978-3-031-31183-3_9)
- Schneider, J. J. et al., 2023. Obstacles on the pathway towards chemical programmability using agglomerations of droplets. Presented at: Artificial Life and Evolutionary Computation 15th Italian Workshop, WIVACE 2021 Winterthur, Switzerland 15-17 September 2021. Artificial Life and Evolutionary Computation 15th Italian Workshop, WIVACE 2021, Winterthur, Switzerland, September 15–17, 2021, Revised Selected Papers. Vol. 1722.Springer. , pp.35-50. (10.1007/978-3-031-23929-8_4)
2022
- Baxani, D. K. et al. 2022. Encapsulated droplet interface bilayers as a platform for high-throughput membrane studies. Soft Matter 18 , pp.5089-5096. (10.1039/D1SM01111A)
- Dimitriou, P. et al. 2022. Active content release from synthetic cell interior towards a novel drug delivery method. Presented at: MicroTAS 2022 Hangzhou, China 23-27 October 2022.
- Dimitriou, P. et al. 2022. Droplet incubator: a new droplet-based model to investigate living cell-synthetic cell interactions. Presented at: MicroTAS 2022 Hangzhou, China 23-27 October 2022.
- Li, J. , Dimitriou, P. and Barrow, D. 2022. Acoustic levitation of complex emulsions and hierarchical soft matter constructs. Presented at: MicroTAS 2022 Hangzhou, China 23-27 October 2022.
- Li, J. et al. 2022. Building programmable multicompartment artificial cells incorporating remotely activated protein channels using microfluidics and acoustic levitation. Nature Communications 13 (1) 4125. (10.1038/s41467-022-31898-w)
- Schneider, J. J. et al., 2022. Paths in a network of polydisperse spherical droplets. Presented at: ALIFE 2022: The 2022 Conference on Artificial Life Online 18-22 July 2022. The 2022 Conference on Artificial Life Proceedings. MIT Press. (10.1162/isal_a_00502)
2021
- Dimitriou, P. et al. 2021. Droplet microfluidics for tumor drug-related studies and programmable artificial cells. Global Challenges 5 (7) 2000123. (10.1002/gch2.202000123)
- Schneider, J. J. et al., 2021. Influence of the geometry on the agglomeration of a polydisperse binary system of spherical particles. Presented at: ALIFE 2021: The 2021 Conference on Artificial Life 19-23 July 2021. Proceedings of the ALIFE 2022: The 2022 Conference on Artificial Life. ALIFE 2021: The 2021 Conference on Artificial Life.. MIT Press(10.1162/isal_a_00392)
2020
- Li, J. et al. 2020. Formation of polarised, functional artificial cells from compartmentalised droplet networks and nanomaterials, using one-step, dual-material 3D-printed microfluidics. Advanced Science 7 (1) 1901719. (10.1002/advs.201901719)
- Li, J. et al. 2020. Generation of complex emulsions using monolithic, dual material 3D-printed microfluidic devices. Presented at: The 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2020) 4-9 October 2020. Cardiff:
2019
- Dillon, C. et al., 2019. Dissolving microneedle based transdermal delivery of therapeutic peptide analogues. International Journal of Pharmaceutics 565 , pp.9-19. (10.1016/j.ijpharm.2019.04.075)
2018
- Baxani, D. K. et al., 2018. An encapsulated droplet interface bilayer array for the high-throughput optical measurement of lipid membranes with single bilayer resolution. Biophysical Journal 114 (3), pp.686A. (10.1016/j.bpj.2017.11.3699)
- Hidalgo San Jose, L. et al. 2018. Microfluidic encapsulation supports stem cell viability, proliferation and neuronal differentiation. Tissue Engineering Part C Methods 24 (3), pp.158-170. (10.1089/ten.TEC.2017.0368)
- Thomas, R. et al., 2018. In-situ fabricated 3D micro-lenses for photonic integrated circuits. Optics Express 26 (10), pp.13436-13442. (10.1364/OE.26.013436)
2017
- Baxani Kamal, D. et al. 2017. The microfluidic manufacture of encapsulated droplet interface bilayers using a hybrid 3D-printed coaxial device. Presented at: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016) Dublin, Ireland 9-13 October 2016. Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016). Red Hook, New York: Curran Associates, Inc.
- Li, J. and Barrow, D. A. 2017. A new droplet-forming fluidic junction for the generation of highly compartmentalised capsules. Lab on a Chip 17 (16), pp.2873-2881. (10.1039/c7lc00618g)
- Li, J. et al. 2017. Formation of chemically responsive multisomes using droplet microfluidics. Presented at: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016) Dublin, Ireland 9-13 October 2016. Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016). Red Hook, NY: Curran Associates, Inc.
- Li, J. et al. 2017. Continuous and scalable polymer capsule processing for inertial fusion energy target shell fabrication using droplet microfluidics. Scientific Reports 7 6302. (10.1038/s41598-017-06746-3)
- Li, J. et al. 2017. An automated system for the shape optimization of double emulsion droplets used in the fabrication of Inertial Fusion Energy target shells. Presented at: The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017) Cardiff 22-26 October 2017.
- Thomas, R. et al. 2017. Photonic integration platform with pump free microfluidics. Optics Express 25 (20), pp.23634-23644. (10.1364/OE.25.023634)
2016
- Baxani, D. K. et al., 2016. Bilayer networks within a hydrogel shell: A robust chassis for artificial cells and a platform for membrane studies. Angewandte Chemie International Edition 55 (46), pp.14240-14245. (10.1002/anie.201607571)
- Loizidou, E. Z. et al., 2016. Evaluation of geometrical effects of microneedles on skin penetration by CT scan and finite element analysis. European Journal of Pharmaceutics and Biopharmaceutics 107 , pp.1-6. (10.1016/j.ejpb.2016.06.023)
- Morgan, A. J. L. et al. 2016. Simple and versatile 3D printed microfluidics using fused filament fabrication. PLoS ONE 11 (4) e0152023. (10.1371/journal.pone.0152023)
2015
- Abduljabar, A. et al. 2015. Adaptive coupling of resonators for efficient microwave heating of microfluidic systems. IEEE Transactions on Microwave Theory and Techniques 63 (11), pp.3681-3690. (10.1109/TMTT.2015.2478004)
- Abduljabar, A. et al. 2015. Microstrip split ring resonator for microsphere detection and characterization. Presented at: 2015 IEEE MTT-S International Microwave Symposium Phoenix, AZ, USA 17-22 May 2015. 2015 IEEE MTT-S International Microwave Symposium. , pp.1-4.
- Abduljabar, A. A. et al. 2015. Modelling and measurements of the microwave dielectric properties of microspheres. IEEE Transactions on Microwave Theory and Techniques 63 (12), pp.4492-4500. (10.1109/TMTT.2015.2495247)
- Loizidou, E. Z. et al. 2015. Structural characterisation and transdermal delivery studies on sugar microneedles: Experimental and finite element modelling analyses. European Journal of Pharmaceutics and Biopharmaceutics 89 , pp.224-231. (10.1016/j.ejpb.2014.11.023)
- Sobiesierski, A. et al. 2015. A two-stage surface treatment for the long-term stability of hydrophilic SU-8. Surface and Interface Analysis 47 (13), pp.1174-1179. (10.1002/sia.5870)
2014
- Abduljabar, A. , Porch, A. and Barrow, D. 2014. Real-time measurements of size, speed, and dielectric property of liquid segments using a microwave microfluidic sensor. Presented at: 2014 IEEE MTT-S International Microwave Symposium (IMS2014) Tampa, FL, USA 1-6 June 2014. 2014 IEEE MTT-S International Microwave Symposium (IMS2014). IEEE. , pp.1-4.
- Li, J. and Barrow, D. 2014. Microfluidic encapsulation of droplet assemblies. Presented at: 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014) Cardiff 26-30 October 2014.
- Li, J. and Barrow, D. 2014. Rapid and precision mass replication of inertial fusion energy targets with multiphase microfluidics. Presented at: The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014) Cardiff 26 - 30 October 2014. 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences. USA: Chemical and Biological Microsystems Society. , pp.1253-1255.
- Rowe, D. J. et al. 2014. Improved split-ring resonator for microfluidic sensing. IEEE Transactions on Microwave Theory and Techniques 62 (3), pp.689-699. (10.1109/TMTT.2014.2299514)
2013
- Morgan, A. J. et al. 2013. Efficient microwave heating of microfluidic systems. Sensors and Actuators B: Chemical 181 , pp.904-909. (10.1016/j.snb.2013.02.099)
- Rowe, D. J. et al. 2013. Microfluidic microwave sensor for simultaneous dielectric and magnetic characterization. IEEE Transactions on Microwave Theory and Techniques 61 (1), pp.234-243. (10.1109/TMTT.2012.2222909)
2012
- Barrow, D. A. et al. 2012. Microfluidic device and methods for construction and application. EP1562708B1[Patent]
- Rowe, D. J. et al. 2012. Microfluidic device for compositional analysis of solvent systems at microwave frequencies. Sensors and Actuators B: Chemical 169 , pp.213-221. (10.1016/j.snb.2012.04.069)
- Rowe, D. J. et al. 2012. Novel coupling structure for the resonant coaxial probe. IEEE Transactions on Microwave Theory and Techniques 60 (6), pp.1699-1708. (10.1109/TMTT.2012.2189124)
2011
- Barrow, D. A. et al. 2011. A microfabricated graphitic carbon column for high performance liquid chromatography. Journal of Chromatography A 1218 (15), pp.1983-1987. (10.1016/j.chroma.2010.11.086)
- Castell, O. K. et al. 2011. Current practices for describing the performance of molecularly imprinted polymers can be misleading and may be hampering the development of the field. Journal of Molecular Recognition 24 (6), pp.1115-1122. (10.1002/jmr.1161)
- Rowe, D. J. et al. 2011. Integrated microwave resonant device for dielectric analysis of microfluidic systems. Journal of Physics: Conference Series 310 (1) 012004. (10.1088/1742-6596/310/1/012004)
- Watkins, C. L. et al., 2011. Co-operative membrane disruption between cell-penetrating peptide and cargo: implications for the therapeutic use of the Bcl-2 converter peptide D-NuBCP-9-r8. Molecular Therapy 19 (12), pp.2124-2132. (10.1038/mt.2011.175)
2010
- Masood, A. , Porch, A. and Barrow, D. A. 2010. Microwave resonators for highly sensitive compositional analysis: applications for solvents in microcapillary systems. Lap Lambert Academic Publishing.
- Naylon, A. J. et al. 2010. Efficient Microwave heating and dielectric characterization of microfluidic systems. Presented at: Proceedings of MicroTAS 2010 Groningen, The Netherlands, pp.2092-2094.
- Porch, A. et al. 2010. Sapphire dielectric resonator for microfluidic compositional analysis. Presented at: Proceedings of MicroTAS 2010 Groningen, The Netherlands, pp.2011-2013.
- Rowe, D. J. et al. 2010. Microwave resonant sensor for real-time continuous-flow measurements of microfluidic systems. Presented at: 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010 : (MicroTAS 2010) Groningen, The Netherlands 3-7 October 2010. Published in: Verpoorte, S. ed. 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010 : (MicroTAS 2010) : Groningen, The Netherlands, 3-7 October 2010. San Diego, CA: Chemical and Biological Microsystems Society. , pp.1004-1006.
2009
- Ahmed-Omer, B. , Barrow, D. A. and Wirth, T. 2009. Heck reactions using segmented flow conditions. Tetrahedron Letters 50 (26), pp.3352-3355. (10.1016/j.tetlet.2009.02.133)
- Castell, O. K. , Allender, C. J. and Barrow, D. A. 2009. Liquid-liquid phase separation: characterisation of a novel device capable of separating particle carrying multiphase flows. Lab on a Chip 9 (3), pp.388-396. (10.1039/b806946h)
- Lalev, G. et al., 2009. Fabrication and validation of fused silica NIL templates incorporating different length scale features. Microelectronic Engineering 86 (4-6), pp.705-708. (10.1016/j.mee.2009.01.074)
2008
- Ahmed, B. , Barrow, D. A. and Wirth, T. 2008. Bi-phasic Reactions in Microreactors. Presented at: Proceedings of the 4th International Conference on Multi-materials Micro Manufacture Cardiff, UKWhittles Publishing Ltd
- Ahmed-Omer, B. , Barrow, D. A. and Wirth, T. 2008. Effect of segmented fluid flow, sonication and phase transfer catalysis on biphasic reactions in capillary microreactors. Chemical Engineering Journal 135 (S1), pp.S280-S283. (10.1016/j.cej.2007.07.017)
- Barrow, D. A. 2008. Properties and uses of microreactors. In: Wirth, T. ed. Microreactors in Organic Chemistry and Catalysis. Weinheim: Wiley-VCH. , pp.43-57.
- Castell, O. K. et al., 2008. A microwave technique for monitoring phase separation of a multi-phase flow regime utilised for continous molecular enrichment. Presented at: Proceedings of MicroTAS Micro total analysis system 2008 San Diego, USA, pp.137-139.
- Castell, O. , Barrow, D. A. and Allender, C. 2008. Microfluidic liquid separation device and methods for construction and application. GB 0816001.2[Patent]
- Castell, O. K. , Allender, C. J. and Barrow, D. A. 2008. Continuous molecular enrichment in microfluidic systems. Lab on a Chip 8 (7), pp.1031-1033. (10.1039/b800521d)
- Lalev, G. et al., 2008. Template fabrication incorporating different length scale features. Presented at: 4th International Conference on Multi-Material Micro Manufacture (4M) Cardiff, UK 9-11 September 2008. Published in: Menz, W. and Dimov, S. S. eds. 4M 2008: Proceedings of the 4th International Conference on Multi-material Micro Manufacture, Cardiff, UK, 9-11 September 2008. Dunbeath: Whittles. , pp.261-264.
- Masood, A. et al., 2008. Split ring resonator technique for compositional analysis of solvents in microcapillary systems. Presented at: Proceedings of MicroTAS San Diego, USA, pp.1636-1628.
2007
- Goeritz, R. et al., 2007. Microwave compositional analysis of solvent matrices in microcapillary manifold systems. Presented at: Proc. 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2007) Paris, France, pp.1689-1691.
2006
- Ahmed, B. , Barrow, D. A. and Wirth, T. 2006. Enhancement of reaction rates by segmented fluid flow in capillary scale reactors. Advanced Synthesis & Catalysis 348 (9), pp.1043-1048. (10.1002/adsc.200505480)
- Castell, O. K. , Allender, C. J. and Barrow, D. A. 2006. Microchip solid-phase-enhanced liquid extractions utilising highly selective molecularly impronted polymers as chemorecognition solvent extraction agents. Presented at: Proceedings of MicroTAS Micro total analysis system 2006 Tokyo, Japan, pp.891-893.
- Castell, O. K. , Allender, C. J. and Barrow, D. A. 2006. Novel biphasic separations utilising highly selective molecularly imprinted polymers as biorecognition solvent extraction agents. Biosensors and bioelectronics 22 (4), pp.526-533. (10.1016/j.bios.2006.07.017)
- Coulman, S. et al. 2006. Minimally invasive cutaneous delivery of macromolecules and plasmid DNA via microneedles. Current drug delivery 3 (1), pp.65-75.
2005
- Velten, T. et al., 2005. Packaging of bio-MEMS: strategies, technologies and applications. IEEE Transactions on Integration and Packaging 28 (4), pp.533-546. (10.1109/TADVP.2005.858427)
- Zhu, J. and Barrow, D. A. 2005. Analysis of droplet size during crossflow membrane emulsification using stationary and vibrating micromachined silicon nitride membranes. Journal of Membrane Science 261 (1-2), pp.136-144. (10.1016/j.memsci.2005.02.038)
2004
- Barrow, D. A. et al. 2004. Novel microfluidic geometries and processing methodologies enabling the precision formation of micro- and nano- particles. WO2004/043598[Patent]
- Barrow, D. A. et al. 2004. Method for the bulk machining of fluoropolymer substrates. WO2004044655A1[Patent]
- Chabri, F. et al., 2004. Microfabricated silicon microneedles for nonviral cutaneous gene delivery. British Journal of Dermatology 150 (5), pp.869-877. (10.1111/j.0007-0963.2004.05921.x)
- Chabri, F. et al., 2004. Microfabricated silicon microneedles for non-viral cutaneous gene delivery. British Journal of Dermatology 150 (5), pp.869-877. (10.1111/j.1365-2133.2004.05921.x)
2003
- Harries, N. et al., 2003. A numerical model for segmented flow in a microreactor. International Journal of Heat and Mass Transfer 46 (17), pp.3313-3322. (10.1016/S0017-9310(03)00120-0)
2002
- Senkans, P. D. , Biasi, V. D. and Barrow, D. A. 2002. Computational simulations of fluid flow dynamics and bead packing in solid phase extraction microsystems.. Presented at: Micro total analysis systems 2002 proceedings of the mTAS2002 symposium Nara, JapanKluwer Academic Publishers. , pp.76-78.
2001
- Shapley, J. D. L. and Barrow, D. A. 2001. Novel patterning method for the electrochemical production of etched silicon. Thin Sold Films 388 (1-2), pp.134-137. (10.1016/S0040-6090(01)00823-9)
- Sparey-Taylor, G. J. et al., 2001. Automated ultrasonic particle processing microsystem. Presented at: Proceedings of SPIE 4236 the International Society for Optical Engineering Smart Electronic & MEMS II Melbourne, AustraliaVol. 4236., pp.107-114.
Articles
- Abduljabar, A. et al. 2015. Adaptive coupling of resonators for efficient microwave heating of microfluidic systems. IEEE Transactions on Microwave Theory and Techniques 63 (11), pp.3681-3690. (10.1109/TMTT.2015.2478004)
- Abduljabar, A. A. et al. 2015. Modelling and measurements of the microwave dielectric properties of microspheres. IEEE Transactions on Microwave Theory and Techniques 63 (12), pp.4492-4500. (10.1109/TMTT.2015.2495247)
- Ahmed, B. , Barrow, D. A. and Wirth, T. 2006. Enhancement of reaction rates by segmented fluid flow in capillary scale reactors. Advanced Synthesis & Catalysis 348 (9), pp.1043-1048. (10.1002/adsc.200505480)
- Ahmed-Omer, B. , Barrow, D. A. and Wirth, T. 2008. Effect of segmented fluid flow, sonication and phase transfer catalysis on biphasic reactions in capillary microreactors. Chemical Engineering Journal 135 (S1), pp.S280-S283. (10.1016/j.cej.2007.07.017)
- Ahmed-Omer, B. , Barrow, D. A. and Wirth, T. 2009. Heck reactions using segmented flow conditions. Tetrahedron Letters 50 (26), pp.3352-3355. (10.1016/j.tetlet.2009.02.133)
- Barrow, D. A. et al. 2011. A microfabricated graphitic carbon column for high performance liquid chromatography. Journal of Chromatography A 1218 (15), pp.1983-1987. (10.1016/j.chroma.2010.11.086)
- Baxani, D. K. et al. 2022. Encapsulated droplet interface bilayers as a platform for high-throughput membrane studies. Soft Matter 18 , pp.5089-5096. (10.1039/D1SM01111A)
- Baxani, D. K. et al., 2018. An encapsulated droplet interface bilayer array for the high-throughput optical measurement of lipid membranes with single bilayer resolution. Biophysical Journal 114 (3), pp.686A. (10.1016/j.bpj.2017.11.3699)
- Baxani, D. K. et al., 2016. Bilayer networks within a hydrogel shell: A robust chassis for artificial cells and a platform for membrane studies. Angewandte Chemie International Edition 55 (46), pp.14240-14245. (10.1002/anie.201607571)
- Castell, O. K. , Allender, C. J. and Barrow, D. A. 2006. Novel biphasic separations utilising highly selective molecularly imprinted polymers as biorecognition solvent extraction agents. Biosensors and bioelectronics 22 (4), pp.526-533. (10.1016/j.bios.2006.07.017)
- Castell, O. K. , Allender, C. J. and Barrow, D. A. 2008. Continuous molecular enrichment in microfluidic systems. Lab on a Chip 8 (7), pp.1031-1033. (10.1039/b800521d)
- Castell, O. K. , Allender, C. J. and Barrow, D. A. 2009. Liquid-liquid phase separation: characterisation of a novel device capable of separating particle carrying multiphase flows. Lab on a Chip 9 (3), pp.388-396. (10.1039/b806946h)
- Castell, O. K. et al. 2011. Current practices for describing the performance of molecularly imprinted polymers can be misleading and may be hampering the development of the field. Journal of Molecular Recognition 24 (6), pp.1115-1122. (10.1002/jmr.1161)
- Chabri, F. et al., 2004. Microfabricated silicon microneedles for nonviral cutaneous gene delivery. British Journal of Dermatology 150 (5), pp.869-877. (10.1111/j.0007-0963.2004.05921.x)
- Chabri, F. et al., 2004. Microfabricated silicon microneedles for non-viral cutaneous gene delivery. British Journal of Dermatology 150 (5), pp.869-877. (10.1111/j.1365-2133.2004.05921.x)
- Coulman, S. et al. 2006. Minimally invasive cutaneous delivery of macromolecules and plasmid DNA via microneedles. Current drug delivery 3 (1), pp.65-75.
- Dillon, C. et al., 2019. Dissolving microneedle based transdermal delivery of therapeutic peptide analogues. International Journal of Pharmaceutics 565 , pp.9-19. (10.1016/j.ijpharm.2019.04.075)
- Dimitriou, P. et al. 2024. Manipulation of encapsulated artificial phospholipid membranes using sub-micellar lysolipid concentrations. Communications Chemistry 7 (1) 120. (10.1038/s42004-024-01209-z)
- Dimitriou, P. et al. 2021. Droplet microfluidics for tumor drug-related studies and programmable artificial cells. Global Challenges 5 (7) 2000123. (10.1002/gch2.202000123)
- Harries, N. et al., 2003. A numerical model for segmented flow in a microreactor. International Journal of Heat and Mass Transfer 46 (17), pp.3313-3322. (10.1016/S0017-9310(03)00120-0)
- Hidalgo San Jose, L. et al. 2018. Microfluidic encapsulation supports stem cell viability, proliferation and neuronal differentiation. Tissue Engineering Part C Methods 24 (3), pp.158-170. (10.1089/ten.TEC.2017.0368)
- Lalev, G. et al., 2009. Fabrication and validation of fused silica NIL templates incorporating different length scale features. Microelectronic Engineering 86 (4-6), pp.705-708. (10.1016/j.mee.2009.01.074)
- Li, J. and Barrow, D. A. 2017. A new droplet-forming fluidic junction for the generation of highly compartmentalised capsules. Lab on a Chip 17 (16), pp.2873-2881. (10.1039/c7lc00618g)
- Li, J. et al. 2020. Formation of polarised, functional artificial cells from compartmentalised droplet networks and nanomaterials, using one-step, dual-material 3D-printed microfluidics. Advanced Science 7 (1) 1901719. (10.1002/advs.201901719)
- Li, J. et al. 2022. Building programmable multicompartment artificial cells incorporating remotely activated protein channels using microfluidics and acoustic levitation. Nature Communications 13 (1) 4125. (10.1038/s41467-022-31898-w)
- Li, J. et al. 2017. Continuous and scalable polymer capsule processing for inertial fusion energy target shell fabrication using droplet microfluidics. Scientific Reports 7 6302. (10.1038/s41598-017-06746-3)
- Loizidou, E. Z. et al., 2016. Evaluation of geometrical effects of microneedles on skin penetration by CT scan and finite element analysis. European Journal of Pharmaceutics and Biopharmaceutics 107 , pp.1-6. (10.1016/j.ejpb.2016.06.023)
- Loizidou, E. Z. et al. 2015. Structural characterisation and transdermal delivery studies on sugar microneedles: Experimental and finite element modelling analyses. European Journal of Pharmaceutics and Biopharmaceutics 89 , pp.224-231. (10.1016/j.ejpb.2014.11.023)
- Morgan, A. J. L. et al. 2016. Simple and versatile 3D printed microfluidics using fused filament fabrication. PLoS ONE 11 (4) e0152023. (10.1371/journal.pone.0152023)
- Morgan, A. J. et al. 2013. Efficient microwave heating of microfluidic systems. Sensors and Actuators B: Chemical 181 , pp.904-909. (10.1016/j.snb.2013.02.099)
- Rowe, D. J. et al. 2014. Improved split-ring resonator for microfluidic sensing. IEEE Transactions on Microwave Theory and Techniques 62 (3), pp.689-699. (10.1109/TMTT.2014.2299514)
- Rowe, D. J. et al. 2011. Integrated microwave resonant device for dielectric analysis of microfluidic systems. Journal of Physics: Conference Series 310 (1) 012004. (10.1088/1742-6596/310/1/012004)
- Rowe, D. J. et al. 2012. Microfluidic device for compositional analysis of solvent systems at microwave frequencies. Sensors and Actuators B: Chemical 169 , pp.213-221. (10.1016/j.snb.2012.04.069)
- Rowe, D. J. et al. 2013. Microfluidic microwave sensor for simultaneous dielectric and magnetic characterization. IEEE Transactions on Microwave Theory and Techniques 61 (1), pp.234-243. (10.1109/TMTT.2012.2222909)
- Rowe, D. J. et al. 2012. Novel coupling structure for the resonant coaxial probe. IEEE Transactions on Microwave Theory and Techniques 60 (6), pp.1699-1708. (10.1109/TMTT.2012.2189124)
- Schneider, J. J. et al., 2023. Network creation during agglomeration processes of polydisperse and monodisperse systems of droplets. Communications in Computer and Information Science 1780 , pp.94-106. (10.1007/978-3-031-31183-3_8)
- Shapley, J. D. L. and Barrow, D. A. 2001. Novel patterning method for the electrochemical production of etched silicon. Thin Sold Films 388 (1-2), pp.134-137. (10.1016/S0040-6090(01)00823-9)
- Silver, K. L. et al. 2024. 3D-printed microfluidic-microwave device for droplet network formation and characterisation. Lab on a Chip 24 , pp.5101-5112. (10.1039/D4LC00387J)
- Sobiesierski, A. et al. 2015. A two-stage surface treatment for the long-term stability of hydrophilic SU-8. Surface and Interface Analysis 47 (13), pp.1174-1179. (10.1002/sia.5870)
- Thomas, R. et al. 2017. Photonic integration platform with pump free microfluidics. Optics Express 25 (20), pp.23634-23644. (10.1364/OE.25.023634)
- Thomas, R. et al., 2018. In-situ fabricated 3D micro-lenses for photonic integrated circuits. Optics Express 26 (10), pp.13436-13442. (10.1364/OE.26.013436)
- Velten, T. et al., 2005. Packaging of bio-MEMS: strategies, technologies and applications. IEEE Transactions on Integration and Packaging 28 (4), pp.533-546. (10.1109/TADVP.2005.858427)
- Watkins, C. L. et al., 2011. Co-operative membrane disruption between cell-penetrating peptide and cargo: implications for the therapeutic use of the Bcl-2 converter peptide D-NuBCP-9-r8. Molecular Therapy 19 (12), pp.2124-2132. (10.1038/mt.2011.175)
- Zhu, J. and Barrow, D. A. 2005. Analysis of droplet size during crossflow membrane emulsification using stationary and vibrating micromachined silicon nitride membranes. Journal of Membrane Science 261 (1-2), pp.136-144. (10.1016/j.memsci.2005.02.038)
Book sections
- Barrow, D. A. 2008. Properties and uses of microreactors. In: Wirth, T. ed. Microreactors in Organic Chemistry and Catalysis. Weinheim: Wiley-VCH. , pp.43-57.
Books
- Masood, A. , Porch, A. and Barrow, D. A. 2010. Microwave resonators for highly sensitive compositional analysis: applications for solvents in microcapillary systems. Lap Lambert Academic Publishing.
Conferences
- Abduljabar, A. , Porch, A. and Barrow, D. 2014. Real-time measurements of size, speed, and dielectric property of liquid segments using a microwave microfluidic sensor. Presented at: 2014 IEEE MTT-S International Microwave Symposium (IMS2014) Tampa, FL, USA 1-6 June 2014. 2014 IEEE MTT-S International Microwave Symposium (IMS2014). IEEE. , pp.1-4.
- Abduljabar, A. et al. 2015. Microstrip split ring resonator for microsphere detection and characterization. Presented at: 2015 IEEE MTT-S International Microwave Symposium Phoenix, AZ, USA 17-22 May 2015. 2015 IEEE MTT-S International Microwave Symposium. , pp.1-4.
- Ahmed, B. , Barrow, D. A. and Wirth, T. 2008. Bi-phasic Reactions in Microreactors. Presented at: Proceedings of the 4th International Conference on Multi-materials Micro Manufacture Cardiff, UKWhittles Publishing Ltd
- Baxani Kamal, D. et al. 2017. The microfluidic manufacture of encapsulated droplet interface bilayers using a hybrid 3D-printed coaxial device. Presented at: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016) Dublin, Ireland 9-13 October 2016. Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016). Red Hook, New York: Curran Associates, Inc.
- Castell, O. K. , Allender, C. J. and Barrow, D. A. 2006. Microchip solid-phase-enhanced liquid extractions utilising highly selective molecularly impronted polymers as chemorecognition solvent extraction agents. Presented at: Proceedings of MicroTAS Micro total analysis system 2006 Tokyo, Japan, pp.891-893.
- Castell, O. K. et al., 2008. A microwave technique for monitoring phase separation of a multi-phase flow regime utilised for continous molecular enrichment. Presented at: Proceedings of MicroTAS Micro total analysis system 2008 San Diego, USA, pp.137-139.
- Dimitriou, P. et al. 2022. Active content release from synthetic cell interior towards a novel drug delivery method. Presented at: MicroTAS 2022 Hangzhou, China 23-27 October 2022.
- Dimitriou, P. et al. 2022. Droplet incubator: a new droplet-based model to investigate living cell-synthetic cell interactions. Presented at: MicroTAS 2022 Hangzhou, China 23-27 October 2022.
- Goeritz, R. et al., 2007. Microwave compositional analysis of solvent matrices in microcapillary manifold systems. Presented at: Proc. 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2007) Paris, France, pp.1689-1691.
- Lalev, G. et al., 2008. Template fabrication incorporating different length scale features. Presented at: 4th International Conference on Multi-Material Micro Manufacture (4M) Cardiff, UK 9-11 September 2008. Published in: Menz, W. and Dimov, S. S. eds. 4M 2008: Proceedings of the 4th International Conference on Multi-material Micro Manufacture, Cardiff, UK, 9-11 September 2008. Dunbeath: Whittles. , pp.261-264.
- Li, J. et al. 2017. Formation of chemically responsive multisomes using droplet microfluidics. Presented at: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016) Dublin, Ireland 9-13 October 2016. Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016). Red Hook, NY: Curran Associates, Inc.
- Li, J. and Barrow, D. 2014. Microfluidic encapsulation of droplet assemblies. Presented at: 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014) Cardiff 26-30 October 2014.
- Li, J. and Barrow, D. 2014. Rapid and precision mass replication of inertial fusion energy targets with multiphase microfluidics. Presented at: The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014) Cardiff 26 - 30 October 2014. 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences. USA: Chemical and Biological Microsystems Society. , pp.1253-1255.
- Li, J. , Dimitriou, P. and Barrow, D. 2022. Acoustic levitation of complex emulsions and hierarchical soft matter constructs. Presented at: MicroTAS 2022 Hangzhou, China 23-27 October 2022.
- Li, J. et al. 2020. Generation of complex emulsions using monolithic, dual material 3D-printed microfluidic devices. Presented at: The 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2020) 4-9 October 2020. Cardiff:
- Li, J. et al. 2017. An automated system for the shape optimization of double emulsion droplets used in the fabrication of Inertial Fusion Energy target shells. Presented at: The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017) Cardiff 22-26 October 2017.
- Masood, A. et al., 2008. Split ring resonator technique for compositional analysis of solvents in microcapillary systems. Presented at: Proceedings of MicroTAS San Diego, USA, pp.1636-1628.
- Matuttis, H. et al., 2023. Computational investigation of the clustering of droplets in widening pipe geometries. Presented at: WIVACE 2022, XVI International Workshop on Artificial Life and Evolutionary Computation Gaeta, Italy 14-16 September 2022. Published in: De Stefano, C. , Fontanella, F. and Vanneschi, L. eds. WIVACE 2022. Artificial Life and Evolutionary Computation. Vol. 1780.Communications in Computer and Information Science Cham, Switzerland: Springer. , pp.82-93. (10.1007/978-3-031-31183-3_7)
- Naylon, A. J. et al. 2010. Efficient Microwave heating and dielectric characterization of microfluidic systems. Presented at: Proceedings of MicroTAS 2010 Groningen, The Netherlands, pp.2092-2094.
- Porch, A. et al. 2010. Sapphire dielectric resonator for microfluidic compositional analysis. Presented at: Proceedings of MicroTAS 2010 Groningen, The Netherlands, pp.2011-2013.
- Rowe, D. J. et al. 2010. Microwave resonant sensor for real-time continuous-flow measurements of microfluidic systems. Presented at: 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010 : (MicroTAS 2010) Groningen, The Netherlands 3-7 October 2010. Published in: Verpoorte, S. ed. 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010 : (MicroTAS 2010) : Groningen, The Netherlands, 3-7 October 2010. San Diego, CA: Chemical and Biological Microsystems Society. , pp.1004-1006.
- Schneider, J. J. et al., 2023. Geometric restrictions to the agglomeration of spherical particles. Presented at: Artificial Life and Evolutionary Computation 15th Italian Workshop, WIVACE 2021, Winterthur, Switzerland, Winterthur, Switzerland 15-17 September 2021. Artificial Life and Evolutionary Computation 15th Italian Workshop, WIVACE 2021, Winterthur, Switzerland, September 15–17, 2021, Revised Selected Papers. Vol. 1722.Springer. , pp.72-84. (10.1007/978-3-031-23929-8_7)
- Schneider, J. J. et al., 2021. Influence of the geometry on the agglomeration of a polydisperse binary system of spherical particles. Presented at: ALIFE 2021: The 2021 Conference on Artificial Life 19-23 July 2021. Proceedings of the ALIFE 2022: The 2022 Conference on Artificial Life. ALIFE 2021: The 2021 Conference on Artificial Life.. MIT Press(10.1162/isal_a_00392)
- Schneider, J. J. et al., 2022. Paths in a network of polydisperse spherical droplets. Presented at: ALIFE 2022: The 2022 Conference on Artificial Life Online 18-22 July 2022. The 2022 Conference on Artificial Life Proceedings. MIT Press. (10.1162/isal_a_00502)
- Schneider, J. J. et al., 2023. Artificial chemistry performed in an agglomeration of droplets with restricted molecule transfer. Presented at: WIVACE 2022, XVI International Workshop on Artificial Life and Evolutionary Computation Gaeta, Italy 14-16 September 2022. Published in: De Stefano, C. , Fontanella, F. and Vanneschi, L. eds. WIVACE 2022. Artificial Life and Evolutionary Computation.. Vol. 1780.Communications in Computer and Information Science Cham, Switzerland: Springer. , pp.107-118. (10.1007/978-3-031-31183-3_9)
- Schneider, J. J. et al., 2023. Obstacles on the pathway towards chemical programmability using agglomerations of droplets. Presented at: Artificial Life and Evolutionary Computation 15th Italian Workshop, WIVACE 2021 Winterthur, Switzerland 15-17 September 2021. Artificial Life and Evolutionary Computation 15th Italian Workshop, WIVACE 2021, Winterthur, Switzerland, September 15–17, 2021, Revised Selected Papers. Vol. 1722.Springer. , pp.35-50. (10.1007/978-3-031-23929-8_4)
- Schneider, J. J. et al., 2024. Percolation breakdown in binary and ternary monodisperse and polydisperse systems of spherical particles. Presented at: Italian Workshop on Artificial Life and Evolutionary Computation Venice 6-8 September 2023. Published in: Villani, M. , Cagnoni, S. and Serra, R. eds. Artificial Life and Evolutionary Computation. WIVACE 2023. Vol. 1977.Communications in Computer and Information Science Cham, Switzerland: Springer. , pp.161-174. (10.1007/978-3-031-57430-6_13)
- Schneider, J. J. et al., 2024. Kauffman Model with spatially separated ligation and cleavage reactions. Presented at: Italian Workshop on Artificial Life and Evolutionary Computation Venice 6-8 September 2023. Published in: Villani, M. , Cagnoni, S. and Serra, R. eds. Artificial Life and Evolutionary Computation. WIVACE 2023. Vol. 1977.Communications in Computer and Information Science Cham, Switzerland: Springer. , pp.141-160. (10.1007/978-3-031-57430-6_12)
- Senkans, P. D. , Biasi, V. D. and Barrow, D. A. 2002. Computational simulations of fluid flow dynamics and bead packing in solid phase extraction microsystems.. Presented at: Micro total analysis systems 2002 proceedings of the mTAS2002 symposium Nara, JapanKluwer Academic Publishers. , pp.76-78.
- Sparey-Taylor, G. J. et al., 2001. Automated ultrasonic particle processing microsystem. Presented at: Proceedings of SPIE 4236 the International Society for Optical Engineering Smart Electronic & MEMS II Melbourne, AustraliaVol. 4236., pp.107-114.
Patents
- Barrow, D. A. et al. 2004. Novel microfluidic geometries and processing methodologies enabling the precision formation of micro- and nano- particles. WO2004/043598[Patent]
- Barrow, D. A. et al. 2004. Method for the bulk machining of fluoropolymer substrates. WO2004044655A1[Patent]
- Barrow, D. A. et al. 2012. Microfluidic device and methods for construction and application. EP1562708B1[Patent]
- Castell, O. , Barrow, D. A. and Allender, C. 2008. Microfluidic liquid separation device and methods for construction and application. GB 0816001.2[Patent]
Research
Contracts
| Title | People | Sponsor | Value | Duration |
|---|---|---|---|---|
|
AC-DC: Artificial Cells with Distributed Cores to Decipher Protein Function |
Barrow DA | EU-FET Proactive | 572298Euros | 01/01/19-31/12/22 |
| Transfer of expertise and access to microengineering related facilities | Barrow DA | KTP and Modern Water | 141346 | 15/05/2010 - 14/05/2012 |
| The development of a cheap and simple to use self-administrable micro-needle patch device for population-wide sampling of small blood volumes | Matthews I, Gallacher J, Gregory C, Hoogendorn B, Barrow D, Allendar, | Bill and Melinda Gates Foundation | 61381 | 01/05/2012 - 31/10/2013 |
| Nanoscience | Barrow DA | Higher Education Funding Council for Wales | 792000 | 01/04/2004 - 01/04/2006 |
| MetaFAB | Barrow DA | Industrial Advisory Board | 48609 | 03/04/2006 - 02/04/2009 |
| MetaFAB | Barrow DA | DTI | 359999 | 03/04/2006 - 02/04/2009 |
| MetaFAB | Barrow DA | Welsh Development Agency | 400001 | 03/04/2006 - 02/04/2009 |
| Q-chip phase 1 marketing | Barrow DA | Welsh Development Agency | 2920 | 13/02/2003 - 13/05/2003 |
| Q-CHIP technology evaluation and exploitation roadmap | Barrow DA | Education and Learning Wales | 14862 | 26/08/2002 - 31/12/2002 |
| Micro nano education and training consortium (MNTec) | Barrow DA, Mr GJ Sparey-Taylor, Tasker PJ | Welsh Development Agency | 306000 | 01/04/2005 - 31/03/2006 |
| Mass-Manufacturing of Fluoropolymer Microreactors for chemical synthesis | Prof DA Barrow | Department of Trade & Industry | 48174 | 01/05/2002 - 30/10/2002 |
| Micro separations for the enhanced separation and detection of small molecules | Prof DA Barrow | GlaxoSmithKline | 45300 | 01/01/2001 - 31/12/2003 |
| Towards highly advanced membrane emulsification systems (THAMES) | Prof DA Barrow | Commission of European Communities | 175315 | 01/01/2002 - 31/12/2004 |
| Refurbishment of nanofabrication clean room | Prof DA Barrow, (with PHYSX) | Royal Society | 122433 | 01/04/2002 - 01/11/2002 |
| MNT Academy II | Prof DA Barrow, Dr RM Perks | National Assembly for Wales (KEF) | 413346 | 01/08/2006 - 31/12/2007 |
| New Hydrogen storage materials - Investigations through structural and electrical characterisation | Porch A, Barrow D | STFC | 26000 | 01/10/2012 - 30/09/2015 |
| Laser and microfluidic manufacture of novel bio-diagnostic platforms | Barrow D | Ser Cymru NRN AEM Swansea | 90800 | 01/10/2014 - 30/09/2017 |
| On line industrial water quality analysis system for rapid and accurate detection of pathogens AQUALITY | Barrow D | European Commission FP7 | 209757 | 01/12/2011 - 30/11/2013 |
| Virtual design for microfluidic encapsulation process | Barrow D, Jefferson A, Kerfriden P, Phillips T (MATHS) | Ser Cymru NRN Swansea AEM | 150000 | 01/01/2015 - 30/06/2018 |
| ECO-Laserfact-EC)-efficient LASER technology FACTories of the future | Bigot S, Setchi RM, Brousseau E, Petkov P, Barrow D | European Commission | 123091 | 01/05/2012 - 30/04/2015 |
Teaching
David Barrow's diverse research porfolio provides a reservoir of new avenues for both individual 3rd year and Group 4th year research projects, ranging from nuclear fusion targets, transdermal microneedles, acoustric trapping, microencapsulated pharmaceuticals, and artificial cells, all using microfluidics technologies. Since 2024 he assists his successor Dr Jin Li on a variety of research projects including the above-mentioned 3rd and 4th year research projects.
Biography
Education/ Qualifications
1972-1974 National Diploma in Electronic Engineering, N. Glos. Tech. College.
1975-1979 Cardiff University BSc (Hons.) 1st. Class, Natural Sciences (Zoology)
1979-1983 PhD:Resource Partitioning in Bombus species (Cardiff University); Nominated for the Huxley Award, Royal Zoological Society of London.
1995-2000 RAEng/EPSRC Senior Clean Technology Fellow on Precision Farming and Process Industries
2000-2005 Cardiff Uiverrsity, Proferssorial Fellow
2005-2021 Cardiff Uiverrsity ,Proferssor Microfluidic Systems
2024- Professor Emeritus of Microfluidic Systems
Honours and awards
Esteem Summary·
- Researched and published on a wide diversity of subject fields applied to microfabrication, sensors & microfluidics, including: miniaturised instrumentation systems, organ transplant therapy, environmental monitoring, protocell formation, fusion energy targets, stem cell encapsulation, microwave sensors, cell-culture, chromatography, microneedles, etc.· Currently researches multiphase microfluidics applied to fusion energy and protocell formation·
- Author of 91 journal papers, patents and book chapters;
- Co-founded 4 microtech companies - MSTB Ltd, Protasis (UK) Ltd,, Q-Chip Ltd., Nanostrics Ltd. ·
- Raised grant income of >£15M from 13 funding bodies; trained 23 post-doctoral staff. ·
- Supervisor of 28 PhD students; 27 graduated with 100% successful completion in 4 yrs·
- Examined 18 PhD theses. External examiner, Canterbury University (NZ), Madras University (I), National Science Foundation (USA) Dutch Government (NL),
- Flew on Team Ultrasound, 6th ESA Microgravity zero-g Parabolic Flight Campaign,
- Technical Consultant to ESA, Waters Corp., Thermofischer UK Ltd., Gyrus Medical Ltd., Daimler-Benz Aerospace, GSK Ltd. Modern Water Ltd., Q-Chip Ltd., Xtec Ltd. ,·
- Involved in 7 European Projects; work co-founded the ESA Advanced Sensor Initiative·
- EPSRC College member (since 2001); reviewed many grant proposals & sat on many committees including round tables, focus groups, follow-on panels, selection panels, etc.·
- Elected to Cardiff University Senate; selection panel for 26 Chairs
- Advisory Board member TSB NanoKTN, Q-Chip Ltd.
- Invited member BBSRC Regenerative Biology and Stem Cell Working Group
- Founded Cardiff University Da Vinci Innovation Awards (2014-19)
- RAEng Reviewer and Asessmernt Panel member for Leaders in Innovation Scheme (2018-2021)
- Awarded Cardiff University Professor Emeritus of Microfluidics
- Invited judgement panel member, Blatavnik Awards for Young Scientists (2023-25)
Professional memberships
2014 Elected Fellow of the Institute for Engineering Technology
Pre-2012
| 2012 | National Science Foundation (USA) Examiner |
| 2011 | Member, EPSRC Engineering Prioritization Panel |
| 2011 | EPSRC Fellowships Panel |
| 2011 | KTP Technical Consultant to Modern Water Ltd. on microinstrumentation |
| 2011 | Member, EPSRC Career Accelaration and Leadships Selection Panel |
| 2010 | Royal Society Industry Fellowships Examination |
| 2010 | Examiner, Indian Institute of Technology, Madras, India |
| 2010 | Member, EPSRC expert panel: Materials & Medical Engineering |
| 2010 | Co-Chair, Q-Chip Ltd. Scientific Advisory Board |
| 2010 | Elected, Fellow of the Institute for Engineering & Technology |
| 2009 | Member, EPSRC expert panel: Follow-on Fund |
| 2009 | Technical consultant, ThermoFisher Ltd |
| 2008 | Member, NanoKTN Advisory Board |
| 2008 | Chair, Chemistry Innovation KTN Conference on Flow Chemistry |
| 2008 | Technical consultant, GSK Ltd |
| 2008 | Member, EPSRC expert panel: Follow-on Fund |
| 2007 | Chair, AILU Summer Conference on Microprocessing with Lasers |
| 2007 | Chair, EPSRC panel Ultrasonics |
| 2006 | Founder director TSB metaFAB Nanocentre |
| 2004 | Chair, Scientific Advisory Board, Q-Chip Ltd |
| 2004 | Member, DTI Global Watch Microfluidics Mission to Germany |
| 2004 | Chief Scientific Officer , Q-Chip Ltd |
| 2004 | Member, Advisory Panel of the IEE Prof. Microsystems Network |
| 2003 | Inventor & Co-founder Q-Chip Ltd |
| 2003 | Session Chair, World Congr. Med. Phys. & Biomed. Eng. Australia |
| 2002 | Reviewer Dutch and New Zealand Government for MST developments |
| 2001 | Technical consultant, Glaxo Wellcome Ltd |
| 2001 | Member Toshiba Fellowships Committee |
| 2001 | Elected member of EPSRC electoral college |
| 2001 | Chair, Cardiff Centre for Multidisciplinary Microtechnology |
| 2001 | Member, EPSRC expert panel: High Throughput Technologies |
| 2000 | Technical consultant, Waters Corporation |
| 2000 | Inventor & co-founding director, Protasis Corporation USA |
| 2000 | Awarded, Cardiff University Professorship in Microsystems |
| 1999 | Member, Internat. Org. Comm. Transducers 99, Tokyo |
| 1999 | Member, EPSRC Round Table on Microsystems |
| 1999 | Member, EPSRC Expert panel on Microsystems Integration |
| 1999 | Honory member, Faraday Northwest Microsystems Consortium |
| 1998 | Member, Internat. Org. Comm., Eurosensors ’98, Southampton, UK |
| 1998 | Member, EPSRC Round Table, Engineering Challenges for 21st Century |
| 1998 | Member, DTI-EPSRC Foresight Laboratory-on-a-Chip consortium |
| 1997 | Member, International Organising Committee Eurosensors ’97 Warsaw |
| 1997 | Executive member, UK Microengineering Common Interest Group |
| 1997 | Technical consultant, Daimler Benz Aerospace |
| 1997 | Board Member NEXIS IV (EU Network on Multifunctional Microsystems) |
| 1996 | Member, COSPAR Scientific Commission F: Space Life Sciences |
| 1996 | Internat. Organ. Comm. & Sess. Chair, Eurosensors ’96 Stockholm |
| 1996 | Team Ultrasound, 6th ESA Microgravity zero-g Flight Campaign |
| 1996 | Board member, LIGA Club, Daresbury Laboratory, UK |
| 1995 | Awarded, RAEng Clean Technology Senior Fellowship |
| 1992 | Co-founding director, MSTB Ltd |
| 1990 | Technical consultant, Gyrus Medical Ltd |
Academic positions
Professional History
1974-1975 Aviation Electronics Test Engineer, Smith Industries, Cheltehnham
1983-1991 Founder Practitioner, ceramics enterprise (full-time)
1992-2005 Co-founder & Director, MSTB Ltd.
1995-2000 RAEng-EPSRC Clean technology Senior Fellow, Cardiff University
2000-2005 Professorial Fellow, Cardiff University
2005- Professor of Microfluidics, Cardiff University
2006-2011 Founder & Director, TSB Industry Open Access NanoCentre (MNT Network)
2000-2003 Co-founder & Director of Microtechnology Development, Protasis Corporation, USA.
2003-2005 Co-founder & Chief Scientific Officer, Q-Chip Ltd
2011- Co-founder & Director, Nanosterics Ltd.
2011 Elected Fellow of the Institute of Engineering Technology
2014 Innovation Professor, Cardiff School of Engineering
Supervisions
I have researched a very wide diversity of subject matter relating to a diversity of microfluidic based phenomena and devices, including chemical sensors, silicon porous, microacoustics, hybrid integration, micromolding, emulsion and digital microfluidics, chemicals separations, plasma etching, CFD, microwave sensors, laser micromachining and marine microanalysis systems.
Now, I am amalgamagting this knowledge in a, more-or-less singular pursuite, that being towards creating artificial life, enabled using droplet microfluidics, and working with international experts in membrane physics and (bio)chemistry I am interested in co-supervising new PhD or masters students in this field, in my Emeritus Professorial role.
Contact Details
Research themes
Specialisms
- Synthetic biology
- droplet microfluidics
- 3D-printing