Dr Lucy Brookes-Howell
(she/her)
- Available for postgraduate supervision
Teams and roles for Lucy Brookes-Howell
Senior Research Fellow - Qualitative
Overview
I am a Senior Research Fellow (Qualitative) and Head of the Qualitative Research Group - Centre for Trials Research - Cardiff University
I am Co-Lead of the Qualitative Research in Trials (QRiT) target group, within the MRC-NIHR Trials Methodology Research Partnership (TMRP).
I began my research career at the Centre for Language and Communication Research training in interactional sociolinguistics. My doctoral research explored diagnostic uncertainty in genetics and society. Following this I developed international networks with discourse researchers and assisted in the launch of the Annual International Conferences on Communication, Medicine & Ethics and acted as Editorial Associate for the journal Communication & Medicine.
I moved to the South East Wales Trials Unit when it was first established in 2006, now Centre for Trials Research. I initially focused on the use of qualitative methods in infections. I then began to broaden my research portfolio to include the use of qualitative methods with under-served groups, and children/young people and parenting, and using qualitative methods with trials.
I am co-investigator on studies currently or recently funded by NIHR (PLACEMENT, TIPTOE, PRONTO, RAPID, SenITA, BATCH), HCRW Research for Patient and Public Benefit (PERCEIVE, PEACH, PLACEMENT, TRIDENT), UKRI ESRC Council (OSCAR), and Charity Action for Children (MIST). I supervise students at Doctoral and Masters level, and as Fellowship Advisor.
My research interests include:
- Health communication
- Patient voices
- Children, young people and parenting
- Infections
- Using qualitative methods with under-served groups
- Qualitative methods and trials
- Large-scale, multi-country qualitative research design
Publication
2025
- Euden, J. et al. 2025. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients: the PEACH mixed methods study. Health Technology Assessment 29 (52), pp.1-32. (10.3310/GGFF9393)
- Glarou, E. et al. 2025. Building rapport in occupational therapy with autistic children: A discourse analytical study. SSM - Qualitative Research in Health 8 100611. (10.1016/j.ssmqr.2025.100611)
- Henley, J. et al. 2025. Procalcitonin to guide antibiotic use during the first wave of COVID-19 in English and Welsh hospitals: integration and triangulation of findings from quantitative and qualitative sources. BMJ Open 15 e093210. (10.1136/bmjopen-2024-093210)
- Nollett, C. et al. 2025. Discussing data: A UK-wide public consultation on the use of low fidelity synthetic data for research. International Journal of Population Data Science 10 (1) 32. (10.23889/ijpds.v10i1.2962)
- Powell, V. et al. 2025. Exploring the mental health research priorities of parents with depression and their children. BMJ Mental Health 28 (1) e301279. (10.1136/bmjment-2024-301279)
- Rice, F. et al. 2025. Skills for adolescent WELLbeing (SWELL): protocol for a preventive effectiveness randomised controlled trial for young people at high-familial risk of depression with treatment optimisation for parents with depression at study entry comparing online group cognitive behavioural therapy (CBT) with treatment as usual. BMJ Open 15 e100692. (10.1136/bmjopen-2025-100692)
- Waldron, C. et al. 2025. Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT. Health Technology Assessment 29 (16)(10.3310/MBVA3675)
- Waldron, C. et al. 2025. Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH): a pragmatic, multicentre, open-label, two-arm, individually randomised, controlled trial. The Lancet Child & Adolescent Health 9 (2), pp.121-130. (10.1016/S2352-4642(24)00306-7)
2024
- Deere, R. et al. 2024. Multi-domain self-management in older people with osteoarthritis and multimorbidities: protocol for the TIPTOE randomised controlled trial. Trials 25 557. (10.1186/s13063-024-08380-7)
- Gwilym, B. L. et al. 2024. Long-term risk prediction after major lower limb amputation: 1-year results of the PERCEIVE study. BJS Open 8 (1) zrad135. (10.1093/bjsopen/zrad135)
- Lugg-Widger, F. et al. 2024. Exploring public views on the use of synthetic datasets for research - results from the DELIMIT study. International Journal of Population Data Science 9 (5) 426. (10.23889/ijpds.v9i5.2919)
- Milosevic, S. et al. 2024. Rehabilitation experiences following major lower limb amputation due to complications of vascular disease: a UK qualitative study. Disability and Rehabilitation 46 (26), pp.6477-6486. (10.1080/09638288.2024.2329747)
- Randell, E. et al. 2024. Exploring critical intervention features and trial processes in the evaluation of sensory integration therapy for autistic children. BMC Trials 25 (1) 131. (10.1186/s13063-024-07957-6)
- Sandoe, J. A. T. et al., 2024. A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19. Journal of Antimicrobial Chemotherapy 79 (11), pp.2792-2800. dkae246. (10.1093/jac/dkae246)
- Segrott, J. et al. 2024. Integrating qualitative research within a clinical trials unit: developing strategies and understanding their implementation in contexts. Trials 25 (1) 323. (10.1186/s13063-024-08124-7)
- Webb, E. J. D. et al., 2024. The cost-effectiveness of procalcitonin for guiding antibiotic prescribing in individuals hospitalized with COVID-19: part of the PEACH study. Journal of Antimicrobial Chemotherapy 79 (8), pp.1831-1842. dkae167. (10.1093/jac/dkae167)
2023
- Cannings-John, R. et al. 2023. Impact of the COVID-19 pandemic on domiciliary care workers in Wales, UK: a data linkage cohort study using the SAIL Databank. BMJ Open 13 (6) e070637. (10.1136/bmjopen-2022-070637)
- Henley, J. et al. 2023. Developing a model for decision-making around antibiotic prescribing for patients with COVID-19 pneumonia in acute NHS hospitals during the first wave of the COVID-19 pandemic: Qualitative results from the Procalcitonin Evaluation of Antibiotic use in COVID-19 Hospitalised patients (PEACH Study). BMJ Open 13 (12) e077117. (10.1136/bmjopen-2023-077117)
- Simon, N. et al. 2023. The acceptability of a guided internet-based trauma-focused self-help programme (Spring) for post-traumatic stress disorder (PTSD). European Journal of Psychotraumatology 14 (2) 2212554.
2022
- Bisson, J. I. et al. 2022. Guided, internet based, cognitive behavioural therapy for post-traumatic stress disorder: pragmatic, multicentre, randomised controlled non-inferiority trial (RAPID). BMJ 377 e069405. (10.1136/bmj-2021-069405)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalized patients during the first wave of COVID-19: the PEACH study. Presented at: Infection 2021: BSAC Winter Conference Virtual 9-10 December 2021. Vol. 4.Vol. 1. (10.1093/jacamr/dlac004.013)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients (PEACH): protocol for a retrospective observational study. Methods and Protocols 5 (6) 95. (10.3390/mps5060095)
- Euden, J. et al. 2022. PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial. BMJ Open 12 (6) e063424. (10.1136/bmjopen-2022-063424)
- Gwilym, B. L. et al., 2022. Short-term risk prediction after major lower limb amputation: PERCEIVE study. BJS Open 109 (12), pp.1300-1311. (10.1093/bjs/znac309)
- Llewelyn, M. J. et al., 2022. Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data. Journal of Antimicrobial Chemotherapy 77 (4), pp.1189-1196. (10.1093/jac/dkac017)
- Milosevic, S. et al. 2022. PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation: a collaboratiVE study (PERCEIVE)—protocol for the PERCEIVE qualitative study. BMJ Open 12 (1) e053159. (10.1136/bmjopen-2021-053159)
- Milosevic, S. et al. 2022. Understanding the support experiences of families of children with autism and sensory processing difficulties: A qualitative study.. Health Expectations 25 (3), pp.1118-1130. (10.1111/hex.13465)
- Prout, H. et al. 2022. “I don't mean to be rude, but could you put a mask on while I'm here?” A qualitative study of risks experienced by domiciliary care workers in Wales during the COVID‐19 pandemic. Health and Social Care in the Community 30 (6), pp.e6601-e6612. (10.1111/hsc.14109)
- Randell, E. et al. 2022. Sensory integration therapy for children with autism and sensory processing difficulties: the SenITA RCT. Health Technology Assessment 26 (29)(10.3310/TQGE0020)
- Waldron, C. et al. 2022. Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial. BMJ Open 12 (1) e047490. (10.1136/bmjopen-2020-047490)
2021
- Gwilym, B. et al., 2021. PERCEIVE: PrEdiction of Risk and Communication of outcome following major lower limb amputation - a collaboratIVE study. Presented at: National Research Collaborative Meeting 2020 (NRCM 2020) Virtual 19 November - 10 December 2020. Vol. 5.Vol. Supple. Wiley(10.1093/bjsopen/zrab032.089)
- Gwilym, B. L. et al., 2021. The PERCEIVE quantitative study: PrEdiction of Risk and Communication of outcome following major lower-limb amputation: protocol for a collaboratiVE study. BJS Open 5 (6) zrab118. (10.1093/bjsopen/zrab118)
- Lugg-Widger, F. et al. 2021. Establishing the impact of COVID-19 on the health outcomes of domiciliary care workers in Wales using routine data: a protocol for the OSCAR study. International Journal of Population Data Science 5 (4) 08. (10.23889/ijpds.v5i4.1656)
- Milosevic, S. et al. 2021. Exploring patients’ experiences of analgesia after major lower limb amputation: A qualitative study. BMJ Open 11 e054618. (10.1136/bmjopen-2021-054618)
- Moody, G. et al. 2021. What are the challenges when recruiting to a trial in children’s social care? A qualitative evaluation of a trial of foster carer training. Trials 22 241. (10.1186/s13063-021-05186-9)
- Powell, N. et al., 2021. Use of procalcitonin during the first wave of COVID-19 in the acute NHS hospitals: a retrospective observational study. Antibiotics 10 (5) 516. (10.3390/antibiotics10050516)
- Simon, N. et al. 2021. Internet-based psychological therapies: a qualitative study of National Health Service commissioners and managers views. Psychology and Psychotherapy: Theory, Research and Practice 94 (4), pp.994-1014. (10.1111/papt.12341)
2020
- Ambler, G. K. et al. 2020. Development of core outcome sets for people undergoing major lower limb amputation for complications of peripheral vascular disease. European Journal of Vascular and Endovascular Surgery 60 (5), pp.730-738. (10.1016/j.ejvs.2020.06.021)
- Channon, S. et al. 2020. Qualitative process evaluation of the Fostering Changes program for foster carers as part of the Confidence in Care randomized controlled trial. Child Abuse and Neglect 109 104768. (10.1016/j.chiabu.2020.104768)
- Moody, G. et al. 2020. A pragmatic randomised controlled trial of the fostering changes programme. Child Abuse and Neglect 108 104646. (10.1016/j.chiabu.2020.104646)
- Yhnell, E. et al. 2020. A randomised feasibility study of computerised cognitive training as a therapeutic intervention for people with Huntington's disease (CogTrainHD). Pilot and Feasibility Studies 6 88. (10.1186/s40814-020-00623-z)
2019
- Bosanquet, D. et al., 2019. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): results from a randomised controlled feasibility trial. BMJ Open 9 (11) e029233. (10.1136/bmjopen-2019-029233)
- Brookes-Howell, L. et al. 2019. Challenges in managing urinary tract infection and the potential of a point-of-care test guided care in primary care: an international qualitative study. BJGP Open 3 (2) 18X101630. (10.3399/bjgpopen18X101630)
- Randell, E. et al. 2019. Sensory integration therapy versus usual care for sensory processing difficulties in autism spectrum disorder in children: study protocol for a pragmatic randomised controlled trial.. Trials 20 113. (10.1186/s13063-019-3205-y)
2018
- Bosanquet, D. C. et al. 2018. Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. British Journal of Pain 12 (4), pp.257-258. (10.1177/2049463718800736)
- Moody, G. et al. 2018. Evaluating the long-term impact of the Fostering Changes training programme for foster carers in Wales, the Confidence in Care trial: study protocol for a randomized controlled trial. Trials 19 34. (10.1186/s13063-017-2424-3)
- Nollett, C. et al. 2018. Pragmatic RAndomised controlled trial of a trauma-focused guided self-help Programme versus InDividual trauma-focused cognitive Behavioural therapy for post-traumatic stress disorder (RAPID): trial protocol. BMC Psychiatry 18 (1) 77. (10.1186/s12888-018-1665-3)
- Yhnell, E. et al. 2018. Exploring computerised cognitive training as a therapeutic intervention for people with Huntington's disease (CogTrainHD): protocol for a randomised feasibility study. Pilot and Feasibility Studies 4 45. (10.1186/s40814-018-0237-0)
2017
- Ambler, G. K. et al. 2017. Development of a core outcome set for studies involving patients undergoing major lower limb amputation for peripheral arterial disease: study protocol for a systematic review and identification of a core outcome set using a Delphi survey. Trials 18 (1) 628. (10.1186/s13063-017-2358-9)
- Bosanquet, D. C. et al., 2017. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 18 629. (10.1186/s13063-017-2357-x)
- Gillespie, D. et al. 2017. Determinants of initiation, implementation, and discontinuation of amoxicillin by adults with acute cough in primary care. Patient Preference and Adherence 2017 (11), pp.561-569. (10.2147/PPA.S119256)
2015
- Anthierens, S. et al., 2015. Clinicians' views and experiences of interventions to enhance the quality of antibiotic prescribing for acute respiratory tract infections. Journal of General Internal Medicine 30 (4), pp.408-416. (10.1007/s11606-014-3076-6)
2014
- Davies, F. et al. 2014. Primary and secondary care clinicians' views on self-treatment of COPD exacerbations: a multinational qualitative study. Patient Education and Counseling 96 (2), pp.256-263. (10.1016/j.pec.2014.05.011)
- Rooshenas, L. et al., 2014. The influence of children's day care on antibiotic seeking: a mixed methods study. British Journal of General Practice (BJGP) 64 (622), pp.e302-e312. (10.3399/bjgp14X679741)
2013
- Wood, F. C. et al. 2013. Primary care clinicians' perceptions of antibiotic resistance: a multi-country qualitative interview study. Journal of Antimicrobial Chemotherapy 68 (1), pp.237-243. (10.1093/jac/dks338)
2012
- Brookes-Howell, L. et al. 2012. 'The body gets used to them': patients' interpretations of antibiotic resistance and the implications for containment strategies. Journal of General Internal Medicine 27 (7), pp.766-772. (10.1007/s11606-011-1916-1)
- Brookes-Howell, L. et al. 2012. Understanding variation in primary medical care: a nine-country qualitative study of clinicians' accounts of the non-clinical factors that shape antibiotic prescribing decisions for lower respiratory tract infection. BMJ Open 2 (4) e000796. (10.1136/bmjopen-2011-000796)
- Brookes-Howell, L. et al. 2012. Clinical influences on antibiotic prescribing decisions for lower respiratory tract infection: a nine country qualitative study of variation in care. BMJ Open 2 (3) e000795. (10.1136/bmjopen-2011-000795)
2011
- Sarangi, S. et al. 2011. Psychological and sociomoral frames in genetic counseling for predictive testing. In: Sarangi, S. K. , Candlin, C. and Knapp, K. eds. Handbook of Communication in Organisations and Professions. Handbooks of Applied Linguistics Vol. 3.Berlin: De Gruyter Mouton. , pp.235-257.
- Wood, F. C. et al. 2011. A multi-country qualitative study of clinicians' and patients' views on point of care tests for lower respiratory tract infection. Family Practice 28 (6), pp.661-669. (10.1093/fampra/cmr031)
2010
- Francis, N. A. et al. 2010. Missed opportunities for earlier treatment? A qualitative interview study with parents of children admitted to hospital with serious respiratory tract infections. Archives of Disease in Childhood 96 (2), pp.154-159. (10.1136/adc.2010.188680)
2006
- Brookes-Howell, L. 2006. Living without labels: The interactional management of diagnostic uncertainty in the genetic counselling clinic. Social Science & Medicine 63 (12), pp.3080-3091. (10.1016/j.socscimed.2006.08.008)
- Sarangi, S. K. and Brookes-Howell, L. 2006. Recontextualising the familial lifeworld in genetic counselling case notes. In: Gotti, M. and Salager-Meyer, F. eds. Advances in Medical Discourse Analysis: Oral and Written Contexts. Linguistic Insights. Studies in Language and Communication Vol. 45.Bern: Peter Lang. , pp.197-228.
2005
- Brain, K. E. et al. 2005. An exploratory comparison of genetic counselling protocols for HNPCC predictive testing. Clinical Genetics 68 (3), pp.255-261. (10.1111/j.1399-0004.2005.00491.x)
2004
- Sarangi, S. K. et al. 2004. Initiation of reflective frames in counselling for Huntington's Disease predictive testing. Journal of Genetic Counselling 13 (2), pp.135-155. (10.1023/B:JOGC.0000018823.60761.e0)
2003
- Clarke, A. J. et al. 2003. Categorisation practices across professional boundaries: some analytic insights from genetic counselling. Presented at: Annual Meeting of the British Association for Applied Linguistics Cardiff, UK September 2002. Published in: Sarangi, S. K. and Leeuwen, T. eds. Applied Linguistics and Communities of Practice: selected papers from the Annual Meeting of the British Association for Applied Linguistics, Cardiff University, September 2002. British Studies in Applied Linguistics London: Continuum. , pp.150-168.
- Sarangi, S. K. et al. 2003. 'Relatively Speaking' : relativisation of genetic risk in counselling for predictive testing. Health, Risk & Society 5 (2), pp.155-170. (10.1080/1369857031000123939)
2001
- Sarangi, S. K. et al. 2001. The negotiation of therapeutic frames in counselling for predictive genetic testing. Journal of Medical Genetics 38 (Sup.1), pp.S23.
Articles
- Ambler, G. K. et al. 2020. Development of core outcome sets for people undergoing major lower limb amputation for complications of peripheral vascular disease. European Journal of Vascular and Endovascular Surgery 60 (5), pp.730-738. (10.1016/j.ejvs.2020.06.021)
- Ambler, G. K. et al. 2017. Development of a core outcome set for studies involving patients undergoing major lower limb amputation for peripheral arterial disease: study protocol for a systematic review and identification of a core outcome set using a Delphi survey. Trials 18 (1) 628. (10.1186/s13063-017-2358-9)
- Anthierens, S. et al., 2015. Clinicians' views and experiences of interventions to enhance the quality of antibiotic prescribing for acute respiratory tract infections. Journal of General Internal Medicine 30 (4), pp.408-416. (10.1007/s11606-014-3076-6)
- Bisson, J. I. et al. 2022. Guided, internet based, cognitive behavioural therapy for post-traumatic stress disorder: pragmatic, multicentre, randomised controlled non-inferiority trial (RAPID). BMJ 377 e069405. (10.1136/bmj-2021-069405)
- Bosanquet, D. et al., 2019. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): results from a randomised controlled feasibility trial. BMJ Open 9 (11) e029233. (10.1136/bmjopen-2019-029233)
- Bosanquet, D. C. et al. 2018. Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. British Journal of Pain 12 (4), pp.257-258. (10.1177/2049463718800736)
- Bosanquet, D. C. et al., 2017. Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 18 629. (10.1186/s13063-017-2357-x)
- Brain, K. E. et al. 2005. An exploratory comparison of genetic counselling protocols for HNPCC predictive testing. Clinical Genetics 68 (3), pp.255-261. (10.1111/j.1399-0004.2005.00491.x)
- Brookes-Howell, L. 2006. Living without labels: The interactional management of diagnostic uncertainty in the genetic counselling clinic. Social Science & Medicine 63 (12), pp.3080-3091. (10.1016/j.socscimed.2006.08.008)
- Brookes-Howell, L. et al. 2012. 'The body gets used to them': patients' interpretations of antibiotic resistance and the implications for containment strategies. Journal of General Internal Medicine 27 (7), pp.766-772. (10.1007/s11606-011-1916-1)
- Brookes-Howell, L. et al. 2012. Understanding variation in primary medical care: a nine-country qualitative study of clinicians' accounts of the non-clinical factors that shape antibiotic prescribing decisions for lower respiratory tract infection. BMJ Open 2 (4) e000796. (10.1136/bmjopen-2011-000796)
- Brookes-Howell, L. et al. 2012. Clinical influences on antibiotic prescribing decisions for lower respiratory tract infection: a nine country qualitative study of variation in care. BMJ Open 2 (3) e000795. (10.1136/bmjopen-2011-000795)
- Brookes-Howell, L. et al. 2019. Challenges in managing urinary tract infection and the potential of a point-of-care test guided care in primary care: an international qualitative study. BJGP Open 3 (2) 18X101630. (10.3399/bjgpopen18X101630)
- Cannings-John, R. et al. 2023. Impact of the COVID-19 pandemic on domiciliary care workers in Wales, UK: a data linkage cohort study using the SAIL Databank. BMJ Open 13 (6) e070637. (10.1136/bmjopen-2022-070637)
- Channon, S. et al. 2020. Qualitative process evaluation of the Fostering Changes program for foster carers as part of the Confidence in Care randomized controlled trial. Child Abuse and Neglect 109 104768. (10.1016/j.chiabu.2020.104768)
- Davies, F. et al. 2014. Primary and secondary care clinicians' views on self-treatment of COPD exacerbations: a multinational qualitative study. Patient Education and Counseling 96 (2), pp.256-263. (10.1016/j.pec.2014.05.011)
- Deere, R. et al. 2024. Multi-domain self-management in older people with osteoarthritis and multimorbidities: protocol for the TIPTOE randomised controlled trial. Trials 25 557. (10.1186/s13063-024-08380-7)
- Euden, J. et al. 2025. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients: the PEACH mixed methods study. Health Technology Assessment 29 (52), pp.1-32. (10.3310/GGFF9393)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients (PEACH): protocol for a retrospective observational study. Methods and Protocols 5 (6) 95. (10.3390/mps5060095)
- Euden, J. et al. 2022. PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial. BMJ Open 12 (6) e063424. (10.1136/bmjopen-2022-063424)
- Francis, N. A. et al. 2010. Missed opportunities for earlier treatment? A qualitative interview study with parents of children admitted to hospital with serious respiratory tract infections. Archives of Disease in Childhood 96 (2), pp.154-159. (10.1136/adc.2010.188680)
- Gillespie, D. et al. 2017. Determinants of initiation, implementation, and discontinuation of amoxicillin by adults with acute cough in primary care. Patient Preference and Adherence 2017 (11), pp.561-569. (10.2147/PPA.S119256)
- Glarou, E. et al. 2025. Building rapport in occupational therapy with autistic children: A discourse analytical study. SSM - Qualitative Research in Health 8 100611. (10.1016/j.ssmqr.2025.100611)
- Gwilym, B. L. et al. 2024. Long-term risk prediction after major lower limb amputation: 1-year results of the PERCEIVE study. BJS Open 8 (1) zrad135. (10.1093/bjsopen/zrad135)
- Gwilym, B. L. et al., 2022. Short-term risk prediction after major lower limb amputation: PERCEIVE study. BJS Open 109 (12), pp.1300-1311. (10.1093/bjs/znac309)
- Gwilym, B. L. et al., 2021. The PERCEIVE quantitative study: PrEdiction of Risk and Communication of outcome following major lower-limb amputation: protocol for a collaboratiVE study. BJS Open 5 (6) zrab118. (10.1093/bjsopen/zrab118)
- Henley, J. et al. 2025. Procalcitonin to guide antibiotic use during the first wave of COVID-19 in English and Welsh hospitals: integration and triangulation of findings from quantitative and qualitative sources. BMJ Open 15 e093210. (10.1136/bmjopen-2024-093210)
- Henley, J. et al. 2023. Developing a model for decision-making around antibiotic prescribing for patients with COVID-19 pneumonia in acute NHS hospitals during the first wave of the COVID-19 pandemic: Qualitative results from the Procalcitonin Evaluation of Antibiotic use in COVID-19 Hospitalised patients (PEACH Study). BMJ Open 13 (12) e077117. (10.1136/bmjopen-2023-077117)
- Llewelyn, M. J. et al., 2022. Impact of introducing procalcitonin testing on antibiotic usage in acute NHS hospitals during the first wave of COVID-19 in the UK: a controlled interrupted time series analysis of organization-level data. Journal of Antimicrobial Chemotherapy 77 (4), pp.1189-1196. (10.1093/jac/dkac017)
- Lugg-Widger, F. et al. 2021. Establishing the impact of COVID-19 on the health outcomes of domiciliary care workers in Wales using routine data: a protocol for the OSCAR study. International Journal of Population Data Science 5 (4) 08. (10.23889/ijpds.v5i4.1656)
- Lugg-Widger, F. et al. 2024. Exploring public views on the use of synthetic datasets for research - results from the DELIMIT study. International Journal of Population Data Science 9 (5) 426. (10.23889/ijpds.v9i5.2919)
- Milosevic, S. et al. 2022. PrEdiction of Risk and Communication of outcomE followIng major lower limb amputation: a collaboratiVE study (PERCEIVE)—protocol for the PERCEIVE qualitative study. BMJ Open 12 (1) e053159. (10.1136/bmjopen-2021-053159)
- Milosevic, S. et al. 2022. Understanding the support experiences of families of children with autism and sensory processing difficulties: A qualitative study.. Health Expectations 25 (3), pp.1118-1130. (10.1111/hex.13465)
- Milosevic, S. et al. 2021. Exploring patients’ experiences of analgesia after major lower limb amputation: A qualitative study. BMJ Open 11 e054618. (10.1136/bmjopen-2021-054618)
- Milosevic, S. et al. 2024. Rehabilitation experiences following major lower limb amputation due to complications of vascular disease: a UK qualitative study. Disability and Rehabilitation 46 (26), pp.6477-6486. (10.1080/09638288.2024.2329747)
- Moody, G. et al. 2018. Evaluating the long-term impact of the Fostering Changes training programme for foster carers in Wales, the Confidence in Care trial: study protocol for a randomized controlled trial. Trials 19 34. (10.1186/s13063-017-2424-3)
- Moody, G. et al. 2021. What are the challenges when recruiting to a trial in children’s social care? A qualitative evaluation of a trial of foster carer training. Trials 22 241. (10.1186/s13063-021-05186-9)
- Moody, G. et al. 2020. A pragmatic randomised controlled trial of the fostering changes programme. Child Abuse and Neglect 108 104646. (10.1016/j.chiabu.2020.104646)
- Nollett, C. et al. 2018. Pragmatic RAndomised controlled trial of a trauma-focused guided self-help Programme versus InDividual trauma-focused cognitive Behavioural therapy for post-traumatic stress disorder (RAPID): trial protocol. BMC Psychiatry 18 (1) 77. (10.1186/s12888-018-1665-3)
- Nollett, C. et al. 2025. Discussing data: A UK-wide public consultation on the use of low fidelity synthetic data for research. International Journal of Population Data Science 10 (1) 32. (10.23889/ijpds.v10i1.2962)
- Powell, N. et al., 2021. Use of procalcitonin during the first wave of COVID-19 in the acute NHS hospitals: a retrospective observational study. Antibiotics 10 (5) 516. (10.3390/antibiotics10050516)
- Powell, V. et al. 2025. Exploring the mental health research priorities of parents with depression and their children. BMJ Mental Health 28 (1) e301279. (10.1136/bmjment-2024-301279)
- Prout, H. et al. 2022. “I don't mean to be rude, but could you put a mask on while I'm here?” A qualitative study of risks experienced by domiciliary care workers in Wales during the COVID‐19 pandemic. Health and Social Care in the Community 30 (6), pp.e6601-e6612. (10.1111/hsc.14109)
- Randell, E. et al. 2024. Exploring critical intervention features and trial processes in the evaluation of sensory integration therapy for autistic children. BMC Trials 25 (1) 131. (10.1186/s13063-024-07957-6)
- Randell, E. et al. 2019. Sensory integration therapy versus usual care for sensory processing difficulties in autism spectrum disorder in children: study protocol for a pragmatic randomised controlled trial.. Trials 20 113. (10.1186/s13063-019-3205-y)
- Randell, E. et al. 2022. Sensory integration therapy for children with autism and sensory processing difficulties: the SenITA RCT. Health Technology Assessment 26 (29)(10.3310/TQGE0020)
- Rice, F. et al. 2025. Skills for adolescent WELLbeing (SWELL): protocol for a preventive effectiveness randomised controlled trial for young people at high-familial risk of depression with treatment optimisation for parents with depression at study entry comparing online group cognitive behavioural therapy (CBT) with treatment as usual. BMJ Open 15 e100692. (10.1136/bmjopen-2025-100692)
- Rooshenas, L. et al., 2014. The influence of children's day care on antibiotic seeking: a mixed methods study. British Journal of General Practice (BJGP) 64 (622), pp.e302-e312. (10.3399/bjgp14X679741)
- Sandoe, J. A. T. et al., 2024. A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19. Journal of Antimicrobial Chemotherapy 79 (11), pp.2792-2800. dkae246. (10.1093/jac/dkae246)
- Sarangi, S. K. et al. 2004. Initiation of reflective frames in counselling for Huntington's Disease predictive testing. Journal of Genetic Counselling 13 (2), pp.135-155. (10.1023/B:JOGC.0000018823.60761.e0)
- Sarangi, S. K. et al. 2003. 'Relatively Speaking' : relativisation of genetic risk in counselling for predictive testing. Health, Risk & Society 5 (2), pp.155-170. (10.1080/1369857031000123939)
- Sarangi, S. K. et al. 2001. The negotiation of therapeutic frames in counselling for predictive genetic testing. Journal of Medical Genetics 38 (Sup.1), pp.S23.
- Segrott, J. et al. 2024. Integrating qualitative research within a clinical trials unit: developing strategies and understanding their implementation in contexts. Trials 25 (1) 323. (10.1186/s13063-024-08124-7)
- Simon, N. et al. 2023. The acceptability of a guided internet-based trauma-focused self-help programme (Spring) for post-traumatic stress disorder (PTSD). European Journal of Psychotraumatology 14 (2) 2212554.
- Simon, N. et al. 2021. Internet-based psychological therapies: a qualitative study of National Health Service commissioners and managers views. Psychology and Psychotherapy: Theory, Research and Practice 94 (4), pp.994-1014. (10.1111/papt.12341)
- Waldron, C. et al. 2025. Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT. Health Technology Assessment 29 (16)(10.3310/MBVA3675)
- Waldron, C. et al. 2025. Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH): a pragmatic, multicentre, open-label, two-arm, individually randomised, controlled trial. The Lancet Child & Adolescent Health 9 (2), pp.121-130. (10.1016/S2352-4642(24)00306-7)
- Waldron, C. et al. 2022. Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial. BMJ Open 12 (1) e047490. (10.1136/bmjopen-2020-047490)
- Webb, E. J. D. et al., 2024. The cost-effectiveness of procalcitonin for guiding antibiotic prescribing in individuals hospitalized with COVID-19: part of the PEACH study. Journal of Antimicrobial Chemotherapy 79 (8), pp.1831-1842. dkae167. (10.1093/jac/dkae167)
- Wood, F. C. et al. 2011. A multi-country qualitative study of clinicians' and patients' views on point of care tests for lower respiratory tract infection. Family Practice 28 (6), pp.661-669. (10.1093/fampra/cmr031)
- Wood, F. C. et al. 2013. Primary care clinicians' perceptions of antibiotic resistance: a multi-country qualitative interview study. Journal of Antimicrobial Chemotherapy 68 (1), pp.237-243. (10.1093/jac/dks338)
- Yhnell, E. et al. 2018. Exploring computerised cognitive training as a therapeutic intervention for people with Huntington's disease (CogTrainHD): protocol for a randomised feasibility study. Pilot and Feasibility Studies 4 45. (10.1186/s40814-018-0237-0)
- Yhnell, E. et al. 2020. A randomised feasibility study of computerised cognitive training as a therapeutic intervention for people with Huntington's disease (CogTrainHD). Pilot and Feasibility Studies 6 88. (10.1186/s40814-020-00623-z)
Book sections
- Sarangi, S. et al. 2011. Psychological and sociomoral frames in genetic counseling for predictive testing. In: Sarangi, S. K. , Candlin, C. and Knapp, K. eds. Handbook of Communication in Organisations and Professions. Handbooks of Applied Linguistics Vol. 3.Berlin: De Gruyter Mouton. , pp.235-257.
- Sarangi, S. K. and Brookes-Howell, L. 2006. Recontextualising the familial lifeworld in genetic counselling case notes. In: Gotti, M. and Salager-Meyer, F. eds. Advances in Medical Discourse Analysis: Oral and Written Contexts. Linguistic Insights. Studies in Language and Communication Vol. 45.Bern: Peter Lang. , pp.197-228.
Conferences
- Clarke, A. J. et al. 2003. Categorisation practices across professional boundaries: some analytic insights from genetic counselling. Presented at: Annual Meeting of the British Association for Applied Linguistics Cardiff, UK September 2002. Published in: Sarangi, S. K. and Leeuwen, T. eds. Applied Linguistics and Communities of Practice: selected papers from the Annual Meeting of the British Association for Applied Linguistics, Cardiff University, September 2002. British Studies in Applied Linguistics London: Continuum. , pp.150-168.
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalized patients during the first wave of COVID-19: the PEACH study. Presented at: Infection 2021: BSAC Winter Conference Virtual 9-10 December 2021. Vol. 4.Vol. 1. (10.1093/jacamr/dlac004.013)
- Gwilym, B. et al., 2021. PERCEIVE: PrEdiction of Risk and Communication of outcome following major lower limb amputation - a collaboratIVE study. Presented at: National Research Collaborative Meeting 2020 (NRCM 2020) Virtual 19 November - 10 December 2020. Vol. 5.Vol. Supple. Wiley(10.1093/bjsopen/zrab032.089)
Research
Current and Recent Grants
- Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT). 2022-2026. Funder: NIHR. £1,635,918. Co-investigator. Chief Investigator: Dave Bosanquet.
- Multi-domain self-management in older people with Osteoarthritis with multiple-morbidities (TIPTOE). 2023-2026. Funder: NIHR. £1,715,355. Co-investigator. Chief Investigator: Kate Button.
- PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the Emergency Department (PRONTO). Funder: NIHR HTA Programme. £1,968,786. Co-investigator. Chief Investigator: Neil French.
- Prediction of risk and communication of outcomes following major lower limb amputation: a collaborative study. Health and Care Research Wales (PERCEIVE). £229,225. Co-investigator. Chief Investigator: Dave Bosanquet.
- Procalcitonin: Evaluation of Antibiotic use in COVID-19 Hospitalised patients (PEACH). Funder: NIHR COVID Learning and Recovery Call. £731,858. Co-investigator and Work Package Lead. Chief Investigator: Jon Sandoe/Enitan Carrol.
- Establishing the impact of COVID-19 on the health of domiciliary care workers in Wales: developing a model for UK service planning and carer support (OSCAR). Funder: UKRI ESRC Council. £419,092. Co-investigator. Chief Investigator: Mike Robling, Rebecca Cannings-John.
- Understanding multi-party communication in therapy sessions for children with Autism Spectrum Disorder and SPD. School of Medicine Studentship Programme. Chief Investigator and Lead Supervisor.
- Title: TRIal designs for DElivery of Novel Therapies for Neurodegeneration (TRIDENT). Funder: Health & Care Research Wales, Research for Patient and Public Benefit Wales (RfPPB). £223,132.00. Co-investigator. Chief Investigator: Ann Rosser.
- Title: Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (The BATCH Trial). Funder: NIHR Health Technology Assessment Programme £1.4 million. Co-investigator. Chief Investigator: Enitan Carrol.
- Title: Perineural Local Anaesthetic Catheter aftEr Major lowEr limb amputatioN Trial (PLACEMENT). Funder: Health & Care Research Wales, Research for Patient and Public Benefit Wales (RfPPB). £210, 552. Co-investigator. Chief Investigator: Chris Twine.
- Title: A pragmatic Randomised Controlled Trial of Sensory Integration Therapy versus usual care for sensory processing difficulties in Autism Spectrum Disorder in children: impact on behavioural difficulties, adaptive skills and socialisation (SenITA). Funder: NIHR Health Technology Assessment Programme. £1,185,180. Co-investigator. Chief Investigator: Rachel McNamara.
- Title: Pragmatic RAndomised controlled trial of a trauma-focused guided self help Programme versus InDividual Trauma-Focused Cognitive Behavioural Therapy for post traumatic stress disorder (RAPIDTFCBT). Funder: NIHR Health Technology Assessment Programme. £1,135,332.88. Co-investigator. Chief Investigator: Jon Bisson.
- Realist evaluation of the multi-disciplinary intervention service Torfaen (MIST). Funder: Action for Children. £30,292. Co-investigator. Chief Investigator: Sue Channon.
Biography
Qualifications
- 2002 PhD Communication, Cardiff University
- 1998 PgradDip (Distinction) Language and Communication Research, Cardiff University
- 1996 BA(Hons) (First class) Language and Communication, Cardiff University
Academic positions
- 2006-current Research Fellow (Qualitative), Centre for Trials Research, Cardiff University
- 2004-2006 Research Coordinator, Health Communication Research Centre, Cardiff University
- 2000-2004 Research Associate, Health Communication Research Centre Cardiff University
- 1998-2000 Research Assistant, Centre for Language and Communication Research, Cardiff University
Supervisions
I am interested in supervising PhD students, particularly in the areas of:
- Qualitative methods and trials
- Health communication
- Patient experiences of health and illness
Past projects
I have successfully supervised the following PhD students to completion:
- Eleni Glarou. Understanding multi-party communication in therapy sessions for autistic children. 2023.
- Dunla Gallagher. The Healthy Eating and Lifestyle in Pregnancy cluster radomised controlled trial: a 24 months postpartum follow-up study. An evaluation of the effect of a weight management intervention for maternal obesity on maternal and child outcomes at 24 months following birth. 2018.
- Leila Rooshenas. Managing common infections in Day Care settings: Day Care providers' sickness exclusion beliefs, advice, and their consequences for patients. 2012.
I have also successfully supervised students for the MSc in Genetic Counselling and Master's in Public Health programmes.