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Helen Brown

Dr Helen Brown


Lecturer - Microbiology (T&R)

School of Biosciences

+44 29225 14560
Sir Martin Evans Building, Room W2/12, Museum Avenue, Cardiff, CF10 3AX
Available for postgraduate supervision


I am a Lecturer in Microbiology. My research interest is biofilm formation as a resistance and pathogenicity mechanism. My current research focuses on interactions between fibroblasts and opportunistic pathogens within chronic wound infections. Bacteria contaminate and form biofilms within wounds early in the healing process and while we know the majority of wounds contain biofilms, only a subsection of these communities go on to cause symptomatic infections. I hope to understand how host-microbial and microbial-microbial interactions are able to influence wound healing and the opportunity for symptomatic infections to form. I focus predominantly on opportunistic pathogens, such as Staphylococcus aureus, which are often part of the local environmental or host microbial communities, but in the right conditions are able to cause infections. Prior to starting my PhD, I worked for six years in the pharmaceutical industry, using mammalian cell-based assays to assess drug biological safety and potency.










Book sections


Bacterial-host interactions:

  • Interactions between fibroblasts (and their secreted components) and their influence on Staphylococcus aureus pathogenicity
  • Understanding how mixed species bacterial communities respond to the host secretome

Bacterial-bacterial interactions:

  • Understanding how the interplay between commensals and opportunistic pathogens can drive pathogenicity and persistence
  • Using the commensal microbiome community to control opportunistic pathogens

Novel therapeutic interventions for chronic wounds:

  • Using microwaves to stimulate dermal wound healing and resolve chronic wound infections
  • Novel antimicrobial/antibiofilm therapeutic strategies utilising the host secretome


I teach on the following modules:

BI1001 Skills for Science
BI1003 Organisms and the Environment
BI2332 Concepts of Disease
BI3155 Infection biology and Epidemiology

I am also available to supervise BSc, MSc and MRes students


2022: Lecturer in Microbiology, School of Biosciences, Cardiff University

2019 - 2022: Postdoctoral Researcher, School of Dentistry, Cardiff University

2018 - 2019: Postdoctoral Researcher, School of Veterinary Medicine, Surrey University

2016 - 2018: Postdoctoral Researcher, School of Dentistry, Cardiff University

2015 - 2016: Postdoctoral Researcher, Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University

2011 - 2015: PhD student, Institue of Food Research/University of East Anglia

2004 - 2011: Experimental Officer, Biosafety Division, Covance Laboratories Ltd

Honours and awards

2013: Society of General Microbiology Outreach Award

2013: University of East Anglia (CUE EAST) Outreach Newcomer Award

Professional memberships

2012 onwards - member of the Microbiology Society

Committees and reviewing

2020 onwards: Editor of Access Microbiology


  • Aged health care
  • Medical bacteriology
  • Medical microbiology
  • Microbiology