![Joanne Euden](https://profiles-cardiff.imgix.net/attachments/683?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Overview
I am a Research Fellow in the Division of Infections, Inflammation and Immunity at the Centre for Trials Research (CTR) and am the theme lead for Infectious Diseases within the division. Prior to transitioning into clincial research, I was a post-doc at the Wales Heart Reseach Institute at Cardiff University.
My interests are in Point of Care Testing (POCT) and infectious disease diagnostics with a particularly interest in secondary care (Emergency Medicine). However, any trial/study that works towards improving patient care by implementing new and improved interventions to the NHS will gain my interest!
Current trials I am working on include:
PRONTO (https://www.cardiff.ac.uk/centre-for-trials-research/research/studies-and-trials/view/pronto)
PROTECT (https://www.cardiff.ac.uk/centre-for-trials-research/research/studies-and-trials/view/protect)
PEACH (https://www.cardiff.ac.uk/centre-for-trials-research/research/studies-and-trials/view/peach)
RAPID-PROTECTION (https://www.cardiff.ac.uk/centre-for-trials-research/research/studies-and-trials/view/rapid-protection)
ENCEPH-IG (https://www.cardiff.ac.uk/centre-for-trials-research/research/studies-and-trials/view/enceph-ig)
I am open to collaborative approaches within the fields of infections and immunity.
Publication
2024
- Sandoe, J. A. T. et al. 2024. A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19. Journal of Antimicrobial Chemotherapy 79(11), pp. 2792-2800., article number: dkae246. (10.1093/jac/dkae246)
- Webb, E. J. D. et al. 2024. The cost-effectiveness of procalcitonin for guiding antibiotic prescribing in individuals hospitalized with COVID-19: part of the PEACH study. Journal of Antimicrobial Chemotherapy 79(8), pp. 1831-1842., article number: dkae167. (10.1093/jac/dkae167)
- Webb, E. J. D. et al. 2024. Evidence of quality of life for hospitalised patients with COVID-19: a scoping review. Health Technology Assessment (10.3310/ATPR4281)
2023
- Henley, J. et al. 2023. Developing a model for decision-making around antibiotic prescribing for patients with COVID-19 pneumonia in acute NHS hospitals during the first wave of the COVID-19 pandemic: Qualitative results from the Procalcitonin Evaluation of Antibiotic use in COVID-19 Hospitalised patients (PEACH Study). BMJ Open 13(12), article number: e077117. (10.1136/bmjopen-2023-077117)
- Little, P. et al. 2023. Antibiotics for lower respiratory tract infection in children presenting in primary care: ARTIC-PC RCT. Health Technology Assessment 27, article number: 9. (10.3310/DGBV3199)
2022
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients (PEACH): protocol for a retrospective observational study. Methods and Protocols 5(6), article number: 95. (10.3390/mps5060095)
- Chatoo, S. A., Thomas-Jones, E., Pallmann, P. and Euden, J. 2022. Antibiotic prescribing in hospitalized patients with COVID-19 as a function of inflammatory markers in wave 1 versus wave 2: a systematic review. Presented at: BSAC Spring Conference 2022, 10 - 11 May 2022, Vol. 4. Vol. S.2., (10.1093/jacamr/dlac053.012)
- Euden, J. et al. 2022. PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial. BMJ Open 12(6), article number: e063424. (10.1136/bmjopen-2022-063424)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalized patients during the first wave of COVID-19: the PEACH study. Presented at: Infection 2021: BSAC Winter Conference, Virtual, 9-10 December 2021, Vol. 4. Vol. 1., (10.1093/jacamr/dlac004.013)
2021
- Little, P. et al. 2021. Antibiotics for lower Respiratory Tract Infection in Children presenting in Primary Care (ARTIC PC): a randomised placebo controlled trial. The Lancet 398, pp. 1417-1426. (10.1016/S0140-6736(21)01431-8)
- Powell, N. et al. 2021. Use of procalcitonin during the first wave of COVID-19 in the acute NHS hospitals: a retrospective observational study. Antibiotics 10(5), article number: 516. (10.3390/antibiotics10050516)
2013
- Euden, J., Mason, S. and Williams, A. J. 2013. Functional characterization of the cardiac Ryanodine receptor pore-forming region. PLoS ONE 8(6), article number: e66542. (10.1371/journal.pone.0066542)
- Euden, J., Mason, S., Viero, C., Thomas, N. L. and Williams, A. J. 2013. Investigations of the contribution of a putative glycine hinge to ryanodine receptor channel gating. Journal of Biological Chemistry 288(23), pp. 16671-16679. (10.1074/jbc.M113.465310)
2012
- Mason, S., Viero, C., Euden, J., Bannister, M., West, D., Chen, S. R. W. and Williams, A. J. 2012. The contribution of hydrophobic residues in the pore-forming region of the ryanodine receptor channel to block by large tetraalkylammonium cations and Shaker B inactivation peptides. The Journal of General Physiology 140(3), pp. 325-339. (10.1085/jgp.201210851)
- Viero, C., Thomas, N. L., Euden, J., Mason, S. A., George, C. H. and Williams, A. J. 2012. Techniques and methodologies to study the ryanodine receptor at the molecular, subcellular and cellular level. In: Calcium Signaling. Advances in Experimental and Medical Biology Dordrecht: Springer, pp. 183-215., (10.1007/978-94-007-2888-2_8)
- Viero, C., Thomas, N. L., Euden, J., Mason, S., George, C. H. and Williams, A. J. 2012. Techniques and methodologies to study the ryanodine receptor at the molecular, subcellular and cellular level. In: Islam, M. S. ed. Calcium Signaling. Advances in Experimental Medicine and Biology Vol. 740. Dordrecht: Springer, pp. 183-215., (10.1007/978-94-007-2888-2_8)
2010
- Carney, J., Mason, S. A., Viero, C. and Williams, A. J. 2010. The ryanodine receptor pore: Is there a consensus view?. In: Serysheva, I. I. ed. Structure and Function of Calcium Release Channels., Vol. 66. Current Topics in Membranes Elsevier Academic Press In, pp. 49-67., (10.1016/S1063-5823(10)66003-6)
2007
- Carney, J., East, J. M. and Lee, A. G. 2007. Penetration of lipid chains into the transmembrane surface of TbMscL. Biophysical Journal 92, pp. 3556-3563. (10.1529/biophysj.106.102210)
Articles
- Sandoe, J. A. T. et al. 2024. A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19. Journal of Antimicrobial Chemotherapy 79(11), pp. 2792-2800., article number: dkae246. (10.1093/jac/dkae246)
- Webb, E. J. D. et al. 2024. The cost-effectiveness of procalcitonin for guiding antibiotic prescribing in individuals hospitalized with COVID-19: part of the PEACH study. Journal of Antimicrobial Chemotherapy 79(8), pp. 1831-1842., article number: dkae167. (10.1093/jac/dkae167)
- Webb, E. J. D. et al. 2024. Evidence of quality of life for hospitalised patients with COVID-19: a scoping review. Health Technology Assessment (10.3310/ATPR4281)
- Henley, J. et al. 2023. Developing a model for decision-making around antibiotic prescribing for patients with COVID-19 pneumonia in acute NHS hospitals during the first wave of the COVID-19 pandemic: Qualitative results from the Procalcitonin Evaluation of Antibiotic use in COVID-19 Hospitalised patients (PEACH Study). BMJ Open 13(12), article number: e077117. (10.1136/bmjopen-2023-077117)
- Little, P. et al. 2023. Antibiotics for lower respiratory tract infection in children presenting in primary care: ARTIC-PC RCT. Health Technology Assessment 27, article number: 9. (10.3310/DGBV3199)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients (PEACH): protocol for a retrospective observational study. Methods and Protocols 5(6), article number: 95. (10.3390/mps5060095)
- Euden, J. et al. 2022. PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label, randomised controlled trial. BMJ Open 12(6), article number: e063424. (10.1136/bmjopen-2022-063424)
- Little, P. et al. 2021. Antibiotics for lower Respiratory Tract Infection in Children presenting in Primary Care (ARTIC PC): a randomised placebo controlled trial. The Lancet 398, pp. 1417-1426. (10.1016/S0140-6736(21)01431-8)
- Powell, N. et al. 2021. Use of procalcitonin during the first wave of COVID-19 in the acute NHS hospitals: a retrospective observational study. Antibiotics 10(5), article number: 516. (10.3390/antibiotics10050516)
- Euden, J., Mason, S. and Williams, A. J. 2013. Functional characterization of the cardiac Ryanodine receptor pore-forming region. PLoS ONE 8(6), article number: e66542. (10.1371/journal.pone.0066542)
- Euden, J., Mason, S., Viero, C., Thomas, N. L. and Williams, A. J. 2013. Investigations of the contribution of a putative glycine hinge to ryanodine receptor channel gating. Journal of Biological Chemistry 288(23), pp. 16671-16679. (10.1074/jbc.M113.465310)
- Mason, S., Viero, C., Euden, J., Bannister, M., West, D., Chen, S. R. W. and Williams, A. J. 2012. The contribution of hydrophobic residues in the pore-forming region of the ryanodine receptor channel to block by large tetraalkylammonium cations and Shaker B inactivation peptides. The Journal of General Physiology 140(3), pp. 325-339. (10.1085/jgp.201210851)
- Carney, J., East, J. M. and Lee, A. G. 2007. Penetration of lipid chains into the transmembrane surface of TbMscL. Biophysical Journal 92, pp. 3556-3563. (10.1529/biophysj.106.102210)
Book sections
- Viero, C., Thomas, N. L., Euden, J., Mason, S. A., George, C. H. and Williams, A. J. 2012. Techniques and methodologies to study the ryanodine receptor at the molecular, subcellular and cellular level. In: Calcium Signaling. Advances in Experimental and Medical Biology Dordrecht: Springer, pp. 183-215., (10.1007/978-94-007-2888-2_8)
- Viero, C., Thomas, N. L., Euden, J., Mason, S., George, C. H. and Williams, A. J. 2012. Techniques and methodologies to study the ryanodine receptor at the molecular, subcellular and cellular level. In: Islam, M. S. ed. Calcium Signaling. Advances in Experimental Medicine and Biology Vol. 740. Dordrecht: Springer, pp. 183-215., (10.1007/978-94-007-2888-2_8)
- Carney, J., Mason, S. A., Viero, C. and Williams, A. J. 2010. The ryanodine receptor pore: Is there a consensus view?. In: Serysheva, I. I. ed. Structure and Function of Calcium Release Channels., Vol. 66. Current Topics in Membranes Elsevier Academic Press In, pp. 49-67., (10.1016/S1063-5823(10)66003-6)
Conferences
- Chatoo, S. A., Thomas-Jones, E., Pallmann, P. and Euden, J. 2022. Antibiotic prescribing in hospitalized patients with COVID-19 as a function of inflammatory markers in wave 1 versus wave 2: a systematic review. Presented at: BSAC Spring Conference 2022, 10 - 11 May 2022, Vol. 4. Vol. S.2., (10.1093/jacamr/dlac053.012)
- Euden, J. et al. 2022. Procalcitonin evaluation of antibiotic use in COVID-19 hospitalized patients during the first wave of COVID-19: the PEACH study. Presented at: Infection 2021: BSAC Winter Conference, Virtual, 9-10 December 2021, Vol. 4. Vol. 1., (10.1093/jacamr/dlac004.013)
Biography
Career Overview
2022- present Research Fellow (Senior Trial Manager), Centre for Trials Research, Cardiff University
2019 - 2022: Research Associate (Trial Manager), Centre for Trials Research, Cardiff University
2017 - 2019: Research Associate (Trial coordinator), Division of Population Medicine, School of Medicine, Cardiff University
2007 - 2016: Research Associate/Post doc, Institute of Molecular and Experimental Medicine, School of Medicine, Cardiff Univeristy
2001 - 2003: Graduate Research Scientist, UKHSA, Salisbury.
Education and Qualifications
2007: PhD (Biochemistry) School of Biological Sciences, University of Southampton.
'Effects of lipids on the structure of the Mechanosensitive channel, MscL'
A quantitative, lab based project using protein biochemical, biophysical and molecular biological techniques.
2001: BSc(hons) Human Biosciences, School of Biological Sciences, Plymouth University.
Modules included human genetics, applied immunology, applied toxicology, biochemistry, bacteriology & virology and cell biology.
Professional memberships
British Society for Antimicrobial Chemotherapy
GW4 Alliance
UKTMN
Committees and reviewing
NIHR Peer Reviewer
Contact Details
EudenJ@cardiff.ac.uk
+44 29225 10771
Neuadd Meirionnydd, Room 708F, 7th floor., University Hospital of Wales, Heath Park, Cardiff, CF14 4YS
+44 29225 10771
Neuadd Meirionnydd, Room 708F, 7th floor., University Hospital of Wales, Heath Park, Cardiff, CF14 4YS