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Dr Olga Eyre
Clinical Research Fellow, Division of Psychological Medicine and Clinical Neurosciences
Overview
I am a clinical research fellow in Child and Adolescent Psychiatry based at the Wolfson Centre for Young People's Mental Health.
My research to date has focused on irritability, Attention Deficit Hyperactivity Disorder (ADHD) and depression in young people. I completed a Wellcome Trust Clinical Research Training Fellowship in 2019, which expored the link between childhood irritability and later adolescent depression in young people with ADHD and other neurodevelopmental difficulties. I am interested in understanding more about early risk factors for depression, particularly in children and young people with severe irritability and ADHD.
My current role in the Wolfson Centre for Young People's Mental Health involves developing an evidence based mental helth tool kit for schools, and supporting the planning of a randomised controlled trial of a preventative intervention for adolescent depression.
Publication
2024
- Dennison, C. A., Shakeshaft, A., Eyre, O., Tilling, K., Rice, F. and Thapar, A. 2024. Investigating the neurodevelopmental correlates of early adolescent-onset emotional problems. Journal of Affective Disorders 364, pp. 212-220. (10.1016/j.jad.2024.08.008)
2023
- Armitage, J. M. et al. 2023. Validation of the Strengths and Difficulties Questionnaire (SDQ) emotional subscale in assessing depression and anxiety across development. PLoS ONE 18(7), article number: e0288882. (10.1371/journal.pone.0288882)
- Stephens, A. et al. 2023. Developing and validating a prediction model of adolescent major depressive disorder in the offspring of depressed parents. Journal of Child Psychology and Psychiatry 64(3), pp. 367-375. (10.1111/jcpp.13704)
- Eyre, O., Patel, V., Brent, D. and Thapar, A. 2023. Latent bipolar depression – Authors' reply. The Lancet 401(10372), pp. 191-192. (10.1016/S0140-6736(22)02598-3)
2022
- Thapar, A., Eyre, O., Patel, V. and Brent, D. 2022. Depression in young people. The Lancet 400, article number: 10352.
- Niina, A., Eyre, O., Wooton, R., Stergiakouli, E., Thapar, A. and Riglin, L. 2022. Exploring ADHD symptoms and associated impairment across development. Journal of Attention Disorders 26(6), pp. 822-830. (10.1177/10870547211025612)
- Colonna, S., Eyre, O., Agha, S. S., Thapar, A., van Goozen, S. and Langley, K. 2022. Investigating the associations between irritability and hot and cool executive functioning in those with ADHD. BMC Psychiatry 22, article number: 166. (10.1186/s12888-022-03818-1)
2021
- Powell, V. et al. 2021. ADHD in adults with recurrent depression. Journal of Affective Disorders 295, pp. 1153-1160. (10.1016/j.jad.2021.09.010)
- Weavers, B. et al. 2021. The antecedents and outcomes of persistent and remitting adolescent depressive symptom trajectories: a longitudinal, population-based English study. The Lancet Psychiatry 8(12), pp. 1053-1061. (10.1016/S2215-0366(21)00281-9)
- Eyre, O. et al. 2021. Validation of the short Mood and Feelings Questionnaire in young adulthood. Journal of Affective Disorders 294, pp. 883-888. (10.1016/j.jad.2021.07.090)
- Martin, J. et al. 2021. Sex differences in anxiety and depression in children with ADHD investigating genetic liability and comorbidity. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 186(7), pp. 412-422. (10.1002/ajmg.b.32842)
- Riglin, L. et al. 2021. Investigating the validity of the strengths and difficulties questionnaire to assess ADHD in young adulthood. Psychiatry Research 301, article number: 113984. (10.1016/j.psychres.2021.113984)
2020
- Powell, V. et al. 2020. What explains the link between childhood ADHD and adolescent depression? Investigating the role of peer relationships and academic attainment. European Child and Adolescent Psychiatry 29, pp. 1581-1591. (10.1007/s00787-019-01463-w)
- Selous, C., Kelly-Irving, M., Maughan, B., Eyre, O., Rice, F. and Collishaw, S. 2020. Adverse childhood experiences and adult mood problems: evidence from a five-decade prospective birth cohort. Psychological Medicine 50(14), pp. 2444-2451. (10.1017/S003329171900271X)
2019
- Eyre, O., Riglin, L., Stringaris, A., Collishaw, S. and Thapar, A. 2019. Irritability in ADHD: association with later depression symptoms. European Child and Adolescent Psychiatry 28(10), pp. 1375-1384. (10.1007/s00787-019-01303-x)
- Riglin, L. et al. 2019. Identifying novel types of irritability using a developmental genetic approach. American Journal of Psychiatry 176(8), pp. 635-642. (10.1176/appi.ajp.2019.18101134)
- Eyre, O. et al. 2019. Childhood neurodevelopmental difficulties and risk for adolescent depression: the role of irritability. Journal of Child Psychology and Psychiatry 60(8), pp. 866-874. (10.1111/jcpp.13053)
2018
- Fraser, A., Cooper, M., Agha, S. S., Collishaw, S., Rice, F., Thapar, A. and Eyre, O. 2018. The presentation of depression symptoms in attention-deficit/hyperactivity disorder: comparing child and parent reports. Child and Adolescent Mental Health 23(3), pp. 243-250. (10.1111/camh.12253)
- Martin, J. et al. 2018. Sex-specific manifestation of genetic risk for attention deficit hyperactivity disorder in the general population. Journal of Child Psychology and Psychiatry 59(8), pp. 908-916. (10.1111/jcpp.12874)
2017
- Riglin, L. et al. 2017. Investigating the genetic underpinnings of early-life irritability. Translational Psychiatry 7, article number: e1241. (10.1038/tp.2017.212)
- Eyre, O., Langley, K., Stringaris, A., Leibenluft, E., Collishaw, S. and Thapar, A. 2017. Irritability in ADHD: Associations with depression liability. Journal of Affective Disorders 215, pp. 281-287. (10.1016/j.jad.2017.03.050)
- Rice, F. et al. 2017. Antecedents of new-onset major depressive disorder in children and adolescents at high familial risk. JAMA Psychiatry 74(2), pp. 153-160. (10.1001/jamapsychiatry.2016.3140)
- Rice, F., Eyre, O., Riglin, L. and Potter, R. 2017. Adolescent depression and the treatment gap. The Lancet Psychiatry 4(2), pp. 86-87. (10.1016/S2215-0366(17)30004-4)
2016
- Cooper, M., Eyre, O., Doherty, J. L. and Bevan-Jones, R. 2016. Gaining approvals for mental health research in the NHS. BJPscyh Advances 22(1), pp. 64-72. (10.1192/apt.bp.114.014035)
2014
- Eyre, O. et al. 2014. Reported child awareness of parental depression. Psychiatric Bulletin 38(3), pp. 122-127. (10.1192/pb.bp.113.044198)
- Eyre, O. and Thapar, A. 2014. Common adolescent mental disorders: transition to adulthood. The Lancet 383(9926), pp. 1366. (10.1016/S0140-6736(13)62633-1)
2013
- Eyre, O. 2013. Clinical and functional outcomes worse in adults diagnosed with ADHD as children. Evidence-Based Mental Health 16(3), pp. 66. (10.1136/eb-2013-101309)
- Thapar, A., Cooper, M., Eyre, O. and Langley, K. 2013. Practitioner review: what have we learnt about the causes of ADHD?. Journal of Child Psychology and Psychiatry 54(1), pp. 3-16. (10.1111/j.1469-7610.2012.02611.x)
2012
- Potter, R. et al. 2012. Missed opportunities: mental disorder in children of parents with depression. British Journal of General Practice (BJGP) 62(600), pp. e487-e493. (10.3399/bjgp12X652355)
Articles
- Dennison, C. A., Shakeshaft, A., Eyre, O., Tilling, K., Rice, F. and Thapar, A. 2024. Investigating the neurodevelopmental correlates of early adolescent-onset emotional problems. Journal of Affective Disorders 364, pp. 212-220. (10.1016/j.jad.2024.08.008)
- Armitage, J. M. et al. 2023. Validation of the Strengths and Difficulties Questionnaire (SDQ) emotional subscale in assessing depression and anxiety across development. PLoS ONE 18(7), article number: e0288882. (10.1371/journal.pone.0288882)
- Stephens, A. et al. 2023. Developing and validating a prediction model of adolescent major depressive disorder in the offspring of depressed parents. Journal of Child Psychology and Psychiatry 64(3), pp. 367-375. (10.1111/jcpp.13704)
- Eyre, O., Patel, V., Brent, D. and Thapar, A. 2023. Latent bipolar depression – Authors' reply. The Lancet 401(10372), pp. 191-192. (10.1016/S0140-6736(22)02598-3)
- Thapar, A., Eyre, O., Patel, V. and Brent, D. 2022. Depression in young people. The Lancet 400, article number: 10352.
- Niina, A., Eyre, O., Wooton, R., Stergiakouli, E., Thapar, A. and Riglin, L. 2022. Exploring ADHD symptoms and associated impairment across development. Journal of Attention Disorders 26(6), pp. 822-830. (10.1177/10870547211025612)
- Colonna, S., Eyre, O., Agha, S. S., Thapar, A., van Goozen, S. and Langley, K. 2022. Investigating the associations between irritability and hot and cool executive functioning in those with ADHD. BMC Psychiatry 22, article number: 166. (10.1186/s12888-022-03818-1)
- Powell, V. et al. 2021. ADHD in adults with recurrent depression. Journal of Affective Disorders 295, pp. 1153-1160. (10.1016/j.jad.2021.09.010)
- Weavers, B. et al. 2021. The antecedents and outcomes of persistent and remitting adolescent depressive symptom trajectories: a longitudinal, population-based English study. The Lancet Psychiatry 8(12), pp. 1053-1061. (10.1016/S2215-0366(21)00281-9)
- Eyre, O. et al. 2021. Validation of the short Mood and Feelings Questionnaire in young adulthood. Journal of Affective Disorders 294, pp. 883-888. (10.1016/j.jad.2021.07.090)
- Martin, J. et al. 2021. Sex differences in anxiety and depression in children with ADHD investigating genetic liability and comorbidity. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 186(7), pp. 412-422. (10.1002/ajmg.b.32842)
- Riglin, L. et al. 2021. Investigating the validity of the strengths and difficulties questionnaire to assess ADHD in young adulthood. Psychiatry Research 301, article number: 113984. (10.1016/j.psychres.2021.113984)
- Powell, V. et al. 2020. What explains the link between childhood ADHD and adolescent depression? Investigating the role of peer relationships and academic attainment. European Child and Adolescent Psychiatry 29, pp. 1581-1591. (10.1007/s00787-019-01463-w)
- Selous, C., Kelly-Irving, M., Maughan, B., Eyre, O., Rice, F. and Collishaw, S. 2020. Adverse childhood experiences and adult mood problems: evidence from a five-decade prospective birth cohort. Psychological Medicine 50(14), pp. 2444-2451. (10.1017/S003329171900271X)
- Eyre, O., Riglin, L., Stringaris, A., Collishaw, S. and Thapar, A. 2019. Irritability in ADHD: association with later depression symptoms. European Child and Adolescent Psychiatry 28(10), pp. 1375-1384. (10.1007/s00787-019-01303-x)
- Riglin, L. et al. 2019. Identifying novel types of irritability using a developmental genetic approach. American Journal of Psychiatry 176(8), pp. 635-642. (10.1176/appi.ajp.2019.18101134)
- Eyre, O. et al. 2019. Childhood neurodevelopmental difficulties and risk for adolescent depression: the role of irritability. Journal of Child Psychology and Psychiatry 60(8), pp. 866-874. (10.1111/jcpp.13053)
- Fraser, A., Cooper, M., Agha, S. S., Collishaw, S., Rice, F., Thapar, A. and Eyre, O. 2018. The presentation of depression symptoms in attention-deficit/hyperactivity disorder: comparing child and parent reports. Child and Adolescent Mental Health 23(3), pp. 243-250. (10.1111/camh.12253)
- Martin, J. et al. 2018. Sex-specific manifestation of genetic risk for attention deficit hyperactivity disorder in the general population. Journal of Child Psychology and Psychiatry 59(8), pp. 908-916. (10.1111/jcpp.12874)
- Riglin, L. et al. 2017. Investigating the genetic underpinnings of early-life irritability. Translational Psychiatry 7, article number: e1241. (10.1038/tp.2017.212)
- Eyre, O., Langley, K., Stringaris, A., Leibenluft, E., Collishaw, S. and Thapar, A. 2017. Irritability in ADHD: Associations with depression liability. Journal of Affective Disorders 215, pp. 281-287. (10.1016/j.jad.2017.03.050)
- Rice, F. et al. 2017. Antecedents of new-onset major depressive disorder in children and adolescents at high familial risk. JAMA Psychiatry 74(2), pp. 153-160. (10.1001/jamapsychiatry.2016.3140)
- Rice, F., Eyre, O., Riglin, L. and Potter, R. 2017. Adolescent depression and the treatment gap. The Lancet Psychiatry 4(2), pp. 86-87. (10.1016/S2215-0366(17)30004-4)
- Cooper, M., Eyre, O., Doherty, J. L. and Bevan-Jones, R. 2016. Gaining approvals for mental health research in the NHS. BJPscyh Advances 22(1), pp. 64-72. (10.1192/apt.bp.114.014035)
- Eyre, O. et al. 2014. Reported child awareness of parental depression. Psychiatric Bulletin 38(3), pp. 122-127. (10.1192/pb.bp.113.044198)
- Eyre, O. and Thapar, A. 2014. Common adolescent mental disorders: transition to adulthood. The Lancet 383(9926), pp. 1366. (10.1016/S0140-6736(13)62633-1)
- Eyre, O. 2013. Clinical and functional outcomes worse in adults diagnosed with ADHD as children. Evidence-Based Mental Health 16(3), pp. 66. (10.1136/eb-2013-101309)
- Thapar, A., Cooper, M., Eyre, O. and Langley, K. 2013. Practitioner review: what have we learnt about the causes of ADHD?. Journal of Child Psychology and Psychiatry 54(1), pp. 3-16. (10.1111/j.1469-7610.2012.02611.x)
- Potter, R. et al. 2012. Missed opportunities: mental disorder in children of parents with depression. British Journal of General Practice (BJGP) 62(600), pp. e487-e493. (10.3399/bjgp12X652355)
Contact Details
EyreO2@cardiff.ac.uk
+44 29206 88452
Hadyn Ellis Building, Room 2.27, Maindy Road, Cardiff, CF24 4HQ
+44 29206 88452
Hadyn Ellis Building, Room 2.27, Maindy Road, Cardiff, CF24 4HQ