![Nigel Francis MPharmacol, PhD, FRSB, SFHEA, NTF](https://profiles-cardiff.imgix.net/attachments/1015?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Dr Nigel Francis MPharmacol, PhD, FRSB, SFHEA, NTF
Senior Lecturer
School of Biosciences
- FrancisN10@cardiff.ac.uk
- +44 29225 12321
- Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX
- Available for postgraduate supervision
Overview
Understanding how our body defends against disease has been a passion ever since I spent a year working in the Nephrology Department at Heath Hospital during my undergraduate degree. This inspired me to undertake a PhD in immunology at the University of Birmingham looking at rheumatoid arthritis, before returning to Cardiff University as a postdoctoral researcher in complement biology.
More recently my focus has shifted to enhancing immunology education and I was awarded the British Society for Immunology’s Teaching Excellence Award in 2020, the Royal Society of Biology’s Higher Education Bioscience Teacher of the Year Award in 2021 and a National Teaching Fellowship from Advance HE in 2022 for my work in this area. I am a Fellow of the Royal Society of Biology (FRSB) and a Senior Fellow of the Higher Education Academy (SFHEA).
I founded the #DryLabsRealScience network, which provides guidance and resources for bioscience academics looking to enhance laboratory-based teaching. Although established in the face of the COVID-19 pandemic, the innovative ideas shared will have a long-lasting impact on laboratory education.
To facilitate the teaching of immunology and make it more accessible to a wider audience I created Immunology Wars in collaboration with student partners, which explains immunology by aligning the components of the immune system to the characters of Star Wars.
I am currently guest-editing a special issue of Education Science around hybrid practical teaching: https://www.mdpi.com/journal/education/special_issues/hybrid_approaches for more details.
Publication
2022
- Francis, N., Ruckley, D. and Wilkinson, T. 2022. The virtual flow cytometer: A new learning experience and environment for undergraduate teaching. Frontiers of Education 7, article number: 903732. (10.3389/feduc.2022.903732)
- Francis, N. J., Smith, D. P. and Turner, I. J. 2022. Practical approaches to delivering pandemic impacted laboratory teaching. Presented at: 8th International Conference on Higher Education Advances HEAd'22, Valencia, Spain, 14-17 June 2022 Presented at Domenech, J. ed.8th International Conference on Higher Education Advances (HEAd'22). Editorial Universitat Politécnica de Valéncia pp. 521-529., (10.4995/head22.2022.15652)
- Smith, D. and Francis, N. 2022. Engagement with video content in the blended classroom. Essays in Biochemistry 66(1), pp. 5-10. (10.1042/EBC20210055)
2021
- Wilkinson, T. S., Nibbs, R. and Francis, N. J. 2021. Reimagining laboratory-based immunology education in the time of COVID-19. Immunology 163(4), pp. 431-435. (10.1111/imm.13369)
- Francis, N. et al. 2021. COVID as a catalyst: uncovering misaligned power dynamics and the importance of new professional learning networks for higher education science laboratory teaching. EdArXiv
2020
- Francis, N., Stafford, P., Henri, D., Turner, I. and Smith, D. 2020. Reshaping education. Part I: Practical thinking in a pandemic. Biologist 67(5), pp. 24-27.
- Francis, N., Morgan, A., Holm, S., Davey, R., Bodger, O. and Dudley, E. 2020. Adopting a flipped classroom approach for teaching molar calculations to biochemistry and genetics students. Biochemistry and Molecular Biology Education 48(3), pp. 220-226. (10.1002/bmb.21328)
2019
- Jones, N. et al. 2019. Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation. Nature Communications 10(1), article number: 2042. (10.1038/s41467-019-10023-4)
2017
- Jones, N. et al. 2017. Metabolic adaptation of human CD4+ and CD8+ T-Cells to T-Cell receptor-mediated stimulation. Frontiers in Immunology 8, article number: 1516. (10.3389/fimmu.2017.01516)
2015
- Jones, N., Piasecka, J., Bryant, A. H., Jones, R. H., Skibinski, D. O. F., Francis, N. J. and Thornton, C. A. 2015. Bioenergetic analysis of human peripheral blood mononuclear cells. Clinical and Experimental Immunology 182(1), pp. 69-80. (10.1111/cei.12662)
2012
- Francis, N. et al. 2012. A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome. Blood 119(2), pp. 591-601. (10.1182/blood-2011-03-339903)
2011
- Francis, N. et al. 2011. Lactoferrin inhibits neutrophil apoptosis via blockade of proximal apoptotic signaling events. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1813(10), pp. 1822-1826. (10.1016/j.bbamcr.2011.07.004)
- Heurich, M., Martinez-Barricarte, R., Francis, N., Roberts, D. L., Rodriguez de Cordoba, S., Morgan, B. P. and Harris, C. L. 2011. Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proceedings of the National Academy of Sciences of the United States of America 108(21), pp. 8761-8766. (10.1073/pnas.1019338108)
2008
- Wong, S. H., Francis, N., Chahal, H., Raza, K., Salmon, M., Scheel-Toellner, D. and Lord, J. M. 2008. Lactoferrin is a survival factor for neutrophils in rheumatoid synovial fluid. Rheumatology 48(1), pp. 39-44. (10.1093/rheumatology/ken412)
Articles
- Francis, N., Ruckley, D. and Wilkinson, T. 2022. The virtual flow cytometer: A new learning experience and environment for undergraduate teaching. Frontiers of Education 7, article number: 903732. (10.3389/feduc.2022.903732)
- Smith, D. and Francis, N. 2022. Engagement with video content in the blended classroom. Essays in Biochemistry 66(1), pp. 5-10. (10.1042/EBC20210055)
- Wilkinson, T. S., Nibbs, R. and Francis, N. J. 2021. Reimagining laboratory-based immunology education in the time of COVID-19. Immunology 163(4), pp. 431-435. (10.1111/imm.13369)
- Francis, N. et al. 2021. COVID as a catalyst: uncovering misaligned power dynamics and the importance of new professional learning networks for higher education science laboratory teaching. EdArXiv
- Francis, N., Stafford, P., Henri, D., Turner, I. and Smith, D. 2020. Reshaping education. Part I: Practical thinking in a pandemic. Biologist 67(5), pp. 24-27.
- Francis, N., Morgan, A., Holm, S., Davey, R., Bodger, O. and Dudley, E. 2020. Adopting a flipped classroom approach for teaching molar calculations to biochemistry and genetics students. Biochemistry and Molecular Biology Education 48(3), pp. 220-226. (10.1002/bmb.21328)
- Jones, N. et al. 2019. Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation. Nature Communications 10(1), article number: 2042. (10.1038/s41467-019-10023-4)
- Jones, N. et al. 2017. Metabolic adaptation of human CD4+ and CD8+ T-Cells to T-Cell receptor-mediated stimulation. Frontiers in Immunology 8, article number: 1516. (10.3389/fimmu.2017.01516)
- Jones, N., Piasecka, J., Bryant, A. H., Jones, R. H., Skibinski, D. O. F., Francis, N. J. and Thornton, C. A. 2015. Bioenergetic analysis of human peripheral blood mononuclear cells. Clinical and Experimental Immunology 182(1), pp. 69-80. (10.1111/cei.12662)
- Francis, N. et al. 2012. A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome. Blood 119(2), pp. 591-601. (10.1182/blood-2011-03-339903)
- Francis, N. et al. 2011. Lactoferrin inhibits neutrophil apoptosis via blockade of proximal apoptotic signaling events. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1813(10), pp. 1822-1826. (10.1016/j.bbamcr.2011.07.004)
- Heurich, M., Martinez-Barricarte, R., Francis, N., Roberts, D. L., Rodriguez de Cordoba, S., Morgan, B. P. and Harris, C. L. 2011. Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proceedings of the National Academy of Sciences of the United States of America 108(21), pp. 8761-8766. (10.1073/pnas.1019338108)
- Wong, S. H., Francis, N., Chahal, H., Raza, K., Salmon, M., Scheel-Toellner, D. and Lord, J. M. 2008. Lactoferrin is a survival factor for neutrophils in rheumatoid synovial fluid. Rheumatology 48(1), pp. 39-44. (10.1093/rheumatology/ken412)
Conferences
- Francis, N. J., Smith, D. P. and Turner, I. J. 2022. Practical approaches to delivering pandemic impacted laboratory teaching. Presented at: 8th International Conference on Higher Education Advances HEAd'22, Valencia, Spain, 14-17 June 2022 Presented at Domenech, J. ed.8th International Conference on Higher Education Advances (HEAd'22). Editorial Universitat Politécnica de Valéncia pp. 521-529., (10.4995/head22.2022.15652)
Research
My main research is focused on enhancing immunology education through digital co-creation of learning and teaching resources. I firmly believe that students should be involved in the creation of resources to enhance their learning experience. I am particularly interested in the use of digital eLearning tools, including videos and simulations.
These resources can be used for active learning in a flipped classroom, where content is provided before face-to-face teaching occurs. My research in this area looks at how students engage with the flipped learning approach and how to enhance the use of digital material.
I maintain an interest in immunology research, focusing on the areas of rheumatology and immunometabolism, which looks at the role that different fuel sources play on immune cell function.
Teaching
Primary teaching focus
- Immunology
Administrative Roles
- Degree scheme lead for Biomedical Sciences
- Deputy Lead for Assessment and Feedback
- Lead for Digital Education
- Week-long research experience coordinator
Pedagogical Publications
- Francis N.J., Ruckley D. and Wilkinson T.S. (2022). The virtual flow cytometer: A new learning experience and environment for undergraduate teaching. Front. Educ. 7:903732. https://www.doi.org/10.3389/feduc.2022.903732
- Francis N.J., Smith D.P. and Turner I.J. (2022). Practical approaches to delivering pandemic impacted laboratory teaching. In: Domenech, J, (ed.) 8th International Conference on Higher Education Advances (HEAd’22) Universitat Politecnica de Valencia, Valencia, 2022.Valencia, Spain, Editorial Universitat Politécnica de Valéncia, 521-529. https://doi.org/10.4995/head22.2022.15652
- Smith D.P. & Francis N.J. (2022). Engagement with video content in the blended classroom. Essays Biochem. EBC20210055. https://doi.org/10.1042/EBC20210055
- Turner I.J., Bolton-King R.S., Francis N.J., Nichols-Drew L.J. & Smith D.P. (2022). How do you offer students a laboratory learning experience when Covid-19 has closed the labs? Available at: https://digitalculture.jiscinvolve.org/wp/2022/03/09/collaborative-online-communities-of-practice/ – published 17th March 2022
- Francis N.J., Allen M. & Thomas J. (2022). Using group work for assessment – an academic’s perspective. Open Educational Resource, Advance HE. Available at: https://www.advance-he.ac.uk/sites/default/files/2022-03/Using group work for assessment - an academic's perspective.pdf
- Francis N.J. (2022). 'I love group work'...said no student ever! Advance HE. Available at: https://www.advance-he.ac.uk/news-and-views/i-love-group-worksaid-no-student-ever – published 4th March 2022
- Cramman H., Burnham J. A. J., Campbell C. D., Francis N. J., Smith D. P., Spagnoli D., Stewart M.I and Turner I. J. (2021). COVID as a catalyst: Uncovering misaligned power dynamics and the importance of new Professional Learning Networks for Higher Education science laboratory teaching. https://doi.org/10.35542/osf.io/tjphr
- McClure L., Wilmott C.J. & Francis N.J. (2021). Supporting the Transition. What challenges will students entering Higher Education face? The Biologist. 68(3): 8-9. Available at: https://thebiologist.rsb.org.uk/biologist-opinion/preparing-for-the-covid-cohort
- Wilkinson T.S., Nibbs R. and Francis N.J. (2021). Reimagining laboratory‐based immunology education in the time of COVID‐19. Immunology. 163(4): 431-435. http://dx.doi.org/10.1111/imm.13369
- Stafford P., Herni D., Turner I., Smith D.P. and Francis N.J. (2020). Practical thinking in a pandemic. The Biologist. 65(5):24-27. Available at: https://thebiologist.rsb.org.uk/biologist/158-biologist/features/2434-reshaping-education-practical-thinking-in-a-pandemic
- Francis N.J., Smith D.P. and Turner I. (2020). It’s a brave new (educational) world. Advance HE. Available at: https://www.advance-he.ac.uk/news-and-views/its-brave-new-educational-world – published 8th September 2020
- Francis N.J., Smith D.P. and Turner I. (2020). #DryLabsRealScience – together stronger. Advance HE. Available at: https://www.advance-he.ac.uk/news-and-views/drylabsrealscience-together-stronger - published 18th May 2020
- Francis N.J., Morgan A.H., Holm S., Davey R., Bodger O. and Dudley E. (2020). Using a flipped classroom approach to teach calculations. Biochemistry and Molecular Biology Education. 48(3):220-226. https://www.doi.org/10.1002/bmb.21328
- Francis N.J. (2019). The Flipped Classroom – Becoming a Better Teacher. Advance HE. Available at: https://www.advance-he.ac.uk/news-and-views/flipping-the-classroom - published 20th March 2019
Biography
I graduated from the University of Bath in 2004 with a MPharmacol (Masters in Pharmacology) having spent an intercalated research year in the Nephrology Department at Heath Hospital under the supervision of Professor Nick Topley. In 2008 I completed a PhD in immunology from the University of Birmingham in the lab of Professor Janet Lord, investigating the role of the iron binding protein, lactoferrin, in neutrophil survival in rheumatic joints. I then returned to Heath Hospital working for Professor Claire Harris in the Complement Biology Group looking at the structure-function relationship of polymorphic variants of factor H.
In 2011 I moved to Swansea University Medical School where I helped establish immunology teaching across all years of their undergraduate programmes. During my time at Swansea I completed a PGCert in Teaching in Higher Education and acted in a wide range of administrative roles including Deputy Programme Director for Biochemistry.
I re-joined Cardiff University in August 2021, where my teaching focuses on immunology and supporting the provision of physiology.
I am an award-winning lecturer having received Swansea University’s Excellence in Learning and Teaching Award and the British Society for Immunology’s Teaching Excellence Award in 2020. In 2021 I was honoured by the Royal Society of Biology for my work creating the #DryLabsRealScience network winning their Higher Education Bioscience Teacher of the Year Award. In 2022 I was awarded my National Teaching Fellowship by Advance HE.
Honours and awards
- 2022 - National Teaching Fellowship
- 2022 - Nominated for Biochemical Society Teaching Excellence Award
- 2021 - Royal Society of Biology Higher Education Bioscience Teacher of the Year
- 2020 - British Society for Immunology Teaching Excellence Award
- 2020 - Swansea University Excellence in Learning and Teaching Award
Professional memberships
- Fellow of the Royal Society of Biology (FRSB)
- Senior Fellow of the Higher Education Academy (SFHEA)
- Chartered Science Teacher (CSciTeach)
- Member of the British Educational Research Association (BERA)
- Member of the British Society for Immunology (BSI)
- Member of the Biochemical Society
- Member of the RSB Biology Education Research Group (BERG)
Academic positions
- 2021 - present: Senior Lecturer, Cardiff University
- 2011-2021: Lecturer/Senior Lecturer/Associate Professor, Swansea University
- 2008-2011: Research Associate, Cardiff University
Committees and reviewing
- 2021 - present: British Society for Immunology Teaching Affinity Group - Co-Chair
Supervisions
I am available for supervision of self-funded students postgraduate interested in exploring:
- Digital resources in Immunology/Biosciences
- Use of videos and/or simulations in teaching
Current supervision
Engagement
British Society for Immunology Vaccine Ambassador
Research themes
Specialisms
- Immunology
- Digital Education
