Professor Jeremy Hall
Hodge Professor Of Psychiatry
Director of Division of Psychological Medicine and Clinical Neuroscience, Co-Director of Neuroscience and Mental Health Innovation Institute, Hon. Consultant Psychiatrist.
- Media commentator
Overview
I am the Hodge Professor of Psychiatry and Neuroscience at Cardiff University.
My overarching interest is in the role of genetic and environmental risk factors in the development of serious mental illness. In my work I employ a translational approach spanning human and laboratory studies.
I am particularly interested in how identified genetic risk factors affect learning processes in the brain; abnormalities in which underlie key symptoms.
Overall I believe that understanding how genetic risk factors influence the brain and how these responses are modulated by environmental stimuli is crucial to the development of new treatments for psychiatric symptoms. In addition to my research work I am also clinically active and conduct clinics in neuropsychiatry.
Publication
2024
- Hunt, M., Underwood, J., Hubbard, L. and Hall, J. 2024. Risk of physical health comorbidities in autistic adults: a clinical nested cross-sectional study. BJPsych Open 10(6), article number: e182. (10.1192/bjo.2024.777)
- Hall, J. H. et al. 2024. Irritability in young people with copy number variants associated with neurodevelopmental disorders (ND-CNVs). Translational Psychiatry 14(1), article number: 259. (10.1038/s41398-024-02975-z)
- Haddon, J. E. et al. 2024. Linking haploinsufficiency of the autism- and schizophrenia-associated gene Cyfip1 with striatal-limbic-cortical network dysfunction and cognitive inflexibility. Translational Psychiatry 14(1), article number: 256. (10.1038/s41398-024-02969-x)
- Lee, I. O. et al. 2024. The inequity of education, health and care plan provision for children and young people with intellectual and developmental disabilities. Journal of Intellectual Disability Research (10.1111/jir.13139)
- Cabezas De La Fuente, D. et al. 2024. Impaired oxysterol-liver X receptor signaling underlies aberrant cortical neurogenesis in a human stem cell model of neurodevelopmental disorder. Cell Reports 43(3), article number: 113946. (10.1016/j.celrep.2024.113946)
- Peall, K. J., Owen, M. J. and Hall, J. 2024. Rare genetic brain disorders with overlapping neurological and psychiatric phenotypes. Nature Reviews Neurology 20(1), pp. 7-21. (10.1038/s41582-023-00896-x)
- Wellard, N. L., Clifton, N. E., Rees, E., Thomas, K. L. and Hall, J. 2024. The association of hippocampal long-term potentiation-induced gene expression with genetic risk for psychosis. International Journal of Molecular Sciences 25(2), article number: 946. (10.3390/ijms25020946)
2023
- Griesius, S. et al. 2023. A mild impairment in reversal learning in a bowl-digging substrate deterministic task but not other cognitive tests in the Dlg2+/- rat model of genetic risk for psychiatric disorder. Genes, Brain and Behavior 22(6), article number: e12865. (10.1111/gbb.12865)
- Wang, B. et al. 2023. Psychosis endophenotypes: A gene-set-specific polygenic risk score analysis. Schizophrenia Bulletin 49(6), pp. 1625-1636. (10.1093/schbul/sbad088)
- Indrigo, M. et al. 2023. Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinα1/KPNA2. EMBO Molecular Medicine 15(11), article number: e15984. (10.15252/emmm.202215984)
- Kumar, K. et al. 2023. Subcortical brain alterations in carriers of genomic copy number variants. The American Journal of Psychiatry 180(9), pp. 685-698. (10.1176/appi.ajp.20220304)
- Kopal, J. et al. 2023. Rare CNVs and phenome-wide profiling highlight brain structural divergence and phenotypical convergence. Nature Human Behaviour 7, pp. 1001-1007. (10.1038/s41562-023-01541-9)
- Chawner, S. J. et al. 2023. Neurodevelopmental dimensional assessment of young children at high genomic risk of neuropsychiatric conditions. JCPP Advances 3(2), article number: e12162. (10.1002/jcv2.12162)
- Niarchou, M. et al. 2023. Psychopathology in mothers of children with pathogenic copy number variants. Journal of Medical Genetics 60, pp. 706-711. (10.1136/jmg-2022-108752)
- Dec, K., Alsaqati, M., Morgan, J., Deshpande, S., Wood, J., Hall, J. and Harwood, A. J. 2023. A high ratio of linoleic acid (n-6 PUFA) to alpha-linolenic acid (n-3 PUFA) adversely affects early stage of human neuronal differentiation and electrophysiological activity of glutamatergic neurons in vitro. Frontiers in Cell and Developmental Biology 11, article number: 1166808. (10.3389/fcell.2023.1166808)
- Moreau, C. A. et al. 2023. Brain functional connectivity mirrors genetic pleiotropy in psychiatric conditions. Brain 146(4), pp. 1686-1696. (10.1093/brain/awac315)
- Gasalla Canto, P., Manahan-Vaughan, D., Dwyer, D. M., Hall, J. and Méndez-Couz, M. 2023. Characterisation of the neural basis underlying appetitive extinction & renewal in a Cacna1c rats. Neuropharmacology 227, article number: 109444. (10.1016/j.neuropharm.2023.109444)
- Lynham, A. J. et al. 2023. DRAGON-Data: A platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts. BJPsych Open 9(2), article number: e32. (10.1192/bjo.2022.636)
- Dimitriadis, S. I. et al. 2023. Genetic risk for schizophrenia is associated with increased proportion of indirect connections in brain networks revealed by a semi-metric analysis: evidence from population sample stratified for polygenic risk. Cerebral Cortex 33(6), pp. 2997-3011. (10.1093/cercor/bhac256)
- Wolstencroft, J. et al. 2023. Mental health impact of autism on families of children with intellectual and developmental disabilities of genetic origin. JCPP Advances, article number: e12128. (10.1002/jcv2.12128)
- Chawner, S. J. R. A., Evans, A., IMAGINE-ID consortium, ., Williams, N., Owen, M. J., Hall, J. and van den Bree, M. B. M. 2023. Sleep disturbance as a transdiagnostic marker of psychiatric risk in children with neurodevelopmental risk genetic conditions. Translational Psychiatry 13, article number: 7. (10.1038/s41398-022-02296-z)
- Levy, R., Timothy, K., Underwood, J., Hall, J., Bernstein, J. and Pasca, S. 2023. A cross-sectional study of the neuropsychiatric phenotype of CACNA1C-related disorder. Pediatric Neurology 138, pp. 101-106. (10.1016/j.pediatrneurol.2022.10.013)
2022
- Zurek, S., Hall, J., Kutrowski, T. and Cheer, A. 2022. Experimental verification of 2.4 kVAr and 12 kVAr prototype variable inductors controlled by virtual air gaps with magnetic orthogonality. IEEE Transactions on Power Delivery 37(6), pp. 4880-4887. (10.1109/TPWRD.2022.3162174)
- Moon, A. L., Clifton, N. E., Wellard, N., Thomas, K. L., Hall, J. and Brydges, N. M. 2022. Social interaction following prepubertal stress alters prefrontal gene expression associated with cell signalling and oligodendrocytes. Translational Psychiatry 12(1), article number: 516. (10.1038/s41398-022-02280-7)
- Alsaqati, M. et al. 2022. NRSF/REST lies at the intersection between epigenetic regulation, miRNA-mediated gene control and neurodevelopmental pathways associated with Intellectual disability (ID) and Schizophrenia. Translational Psychiatry 12, article number: 438. (10.1038/s41398-022-02199-z)
- Underwood, J., DelPozo-Banos, M., Frizzati, A., Rai, D., John, A. and Hall, J. 2022. Neurological and psychiatric disorders among autistic adults: a population healthcare record study. Psychological Medicine (10.1017/S0033291722002884)
- Clifton, N. et al. 2022. Developmental disruption to the cortical transcriptome and synaptosome in a model of SETD1A loss-of-function. Human Molecular Genetics 31(18), pp. 3095-3106. (10.1093/hmg/ddac105)
- Silva, A. I. et al. 2022. Neuroimaging findings in neurodevelopmental copy number variants: identifying molecular pathways to convergent phenotypes. Biological Psychiatry 92(5), pp. 341-361. (10.1016/j.biopsych.2022.03.018)
- Wolstencroft, J. et al. 2022. Neuropsychiatric risk in children with intellectual disability of genetic origin: IMAGINE, a UK national cohort study. The Lancet Psychiatry 9(9), pp. 715-724. (10.1016/S2215-0366(22)00207-3)
- Underwood, J. F. G., DelPozo-Banos, M., Frizzati, A., John, A. and Hall, J. 2022. Evidence of increasing recorded diagnosis of autism spectrum disorders in Wales, UK – an e-cohort study. Autism 26(6), pp. 1499-1508. (10.1177/13623613211059674)
- Donnelly, N. A. et al. 2022. Sleep EEG in young people with 22q11.2 deletion syndrome: A cross-sectional study of slow-waves, spindles and correlations with memory and neurodevelopmental symptoms. eLife 11, article number: e75482. (10.7554/elife.75482)
- Daughters, K., Rees, A., Hunnikin, L., Wells, A., Hall, J. and van Goozen, S. 2022. Oxytocin administration versus emotion training in healthy males: Considerations for future research. Philosophical Transactions of the Royal Society B: Biological Sciences 377(1858), article number: 20210056. (10.1098/rstb.2021.0056)
- Griesius, S. et al. 2022. Reduced expression of the psychiatric risk gene DLG2 (PSD93) impairs hippocampal synaptic integration and plasticity. Neuropsychopharmacology 47, pp. 1367-1378. (10.1038/s41386-022-01277-6)
- Waldron, S. et al. 2022. Behavioural and molecular characterisation of the Dlg2 haploinsufficiency rat model of genetic risk for psychiatric disorder. Genes, Brain and Behavior 21(4), article number: e12797. (10.1111/gbb.12797)
- Pass, R., Haan, N., Humby, T., Wilkinson, L. S., Hall, J. and Thomas, K. L. 2022. Selective behavioural impairments in mice heterozygous for the cross disorder psychiatric risk gene DLG2. Genes, Brain and Behavior 21(4), article number: e12799. (10.1111/gbb.12799)
- Hall, J. and Bray, N. J. 2022. Schizophrenia genomics: convergence on synaptic development, adult synaptic plasticity, or both?. Biological Psychiatry 91(8), pp. 709-717. (10.1016/j.biopsych.2021.10.018)
- Namkung, H., Thomas, K. L., Hall, J. and Sawa, A. 2022. Parsing neural circuits of fear learning and extinction across basic and clinical neuroscience: Towards better translation. Neuroscience and Biobehavioral Reviews 134, article number: 104502. (10.1016/j.neubiorev.2021.12.025)
- Cunningham, A. C., Hall, J., Owen, M. and van den Bree, M. B. M. 2022. Assessment of emotions and behaviour by the Developmental Behaviour Checklist in young people with neurodevelopmental CNVs. Psychological Medicine 52(3), pp. 574-586. (10.1017/S0033291720002330)
- Tuominen, L., Romaniuk, L., Milad, M. R., Goff, D. C., Hall, J. and Holt, D. J. 2022. Impairment in acquisition of conditioned fear in schizophrenia. Neuropsychopharmacology 47, pp. 681-686. (10.1038/s41386-021-01193-1)
- Warne, N. et al. 2022. Collecting genetic samples and linked mental health data from adolescents in schools: protocol co-production and a mixed-methods pilot of feasibility and acceptability. BMJ Open 12(2), article number: e049283. (10.1136/bmjopen-2021-049283)
- Westacott, L. J. et al. 2022. Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder. Brain, Behavior, and Immunity 99, pp. 70-82. (10.1016/j.bbi.2021.09.005)
2021
- Dimitriadis, S. I. et al. 2021. Global brain flexibility during working memory is reduced in a high genetic risk group for schizophrenia. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 6(12), pp. 1176-1184. (10.1016/j.bpsc.2021.01.007)
- Westacott, L. J. et al. 2021. Dissociable effects of complement C3 and C3aR on survival and morphology of adult born hippocampal neurons, pattern separation, and cognitive flexibility in male mice. Brain, Behavior, and Immunity 98, pp. 136-150. (10.1016/j.bbi.2021.08.215)
- Dimitriadis, S. I. et al. 2021. Genetic risk for schizophrenia is associated with altered visually-induced gamma band activity: evidence from a population sample stratified polygenic risk. Translational Psychiatry 11, article number: 592. (10.1038/s41398-021-01678-z)
- Thygesen, J. H. et al. 2021. Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study. Molecular Psychiatry 26, pp. 5307-5319. (10.1038/s41380-020-0820-7)
- Clifton, N. E. et al. 2021. Developmental profile of psychiatric risk associated with voltage-gated cation channel activity. Biological Psychiatry 90(6) (10.1016/j.biopsych.2021.03.009)
- Silva, A. I. et al. 2021. Analysis of diffusion tensor imaging data from the UK Biobank confirms dosage effect of 15q11.2 copy number variation on white matter and shows association with cognition. Biological Psychiatry 90(5), pp. 307-316. (10.1016/j.biopsych.2021.02.969)
- Clifton, N. E. et al. 2021. Genetic association of FMRP targets with psychiatric disorders. Molecular Psychiatry 26, pp. 2977-2990. (10.1038/s41380-020-00912-2)
- Modenato, C. et al. 2021. Effects of eight neuropsychiatric copy number variants on human brain structure. Translational Psychiatry 11(1), article number: 399. (10.1038/s41398-021-01490-9)
- Hubbard, L. et al. 2021. Rare copy number variations are associated with poorer cognition in schizophrenia. Biological Psychiatry 90(1), pp. 28-34. (10.1016/j.biopsych.2020.11.025)
- Notter, T. et al. 2021. Neuronal activity increases translocator protein (TSPO) levels. Molecular Psychiatry 26, pp. 2025-2037. (10.1038/s41380-020-0745-1)
- Rule, L., Yang, J., Watkin, H., Hall, J. and Brydges, N. M. 2021. Environmental enrichment rescues survival and function of adult-born neurons following early life stress. Molecular Psychiatry 26, pp. 1898-1908. (10.1038/s41380-020-0718-4)
- Tigaret, C. M. et al. 2021. Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by hemizygosity of the psychiatric risk gene Cacna1c. Molecular Psychiatry 26, pp. 1748-1760. (10.1038/s41380-020-01001-0)
- Haan, N., Westacott, L. J., Carter, J., Owen, M. J., Gray, W. P., Hall, J. and Wilkinson, L. S. 2021. Haploinsufficiency of the schizophrenia and autism risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms. Translational Psychiatry 11(1), article number: 313. (10.1038/s41398-021-01415-6)
- Cunningham, A., Hall, J., Owen, M. and Van den Bree, M. 2021. Coordination difficulties, IQ and psychopathology in children with high-risk Copy Number Variants. Psychological Medicine 51(2), pp. 290-299. (10.1017/S0033291719003210)
- Chawner, S. et al. 2021. A genetics-first approach to dissecting the heterogeneity of autism: phenotypic comparison of autism risk copy number variants. American Journal of Psychiatry 178(1), pp. 77-86. (10.1176/appi.ajp.2020.20010015)
- Sønderby, I. E., Hall, J., Owen, M., Van Den Bree, M., Linden, D., Silva, A. and Doherty, J. 2021. 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans. Translational Psychiatry 11, article number: 182. (10.1038/s41398-021-01213-0)
2020
- Moon, A. L., Brydges, N. M., Wilkinson, L. S., Hall, J. and Thomas, K. L. 2020. Cacna1c hemizygosity results in aberrant fear conditioning to neutral stimuli. Schizophrenia Bulletin 46(5), pp. 1231-1238. (10.1093/schbul/sbz127)
- Dima, D. C. et al. 2020. Electrophysiological network alterations in adults with copy number variants associated with high neurodevelopmental risk. Translational Psychiatry 10, article number: 324. (10.1038/s41398-020-00998-w)
- Cunningham, A., Fung, W., Massey, T., Hall, J., Owen, M., Van Den Bree, M. and Peall, K. 2020. Movement disorder phenotypes in children with 22q11.2 deletion syndrome. Movement Disorders 35(7), pp. 1272-1274. (10.1002/mds.28078)
- Corcoran, M., Hawkins, E. L., O'Hora, D., Whalley, H. C., Hall, J., Lawrie, S. M. and Dauvermann, M. R. 2020. Are working memory and glutamate concentrations involved in early-life stress and severity of psychosis?. Brain and Behavior 10(6), article number: e01616. (10.1002/brb3.1616)
- Moulding, H., Bartsch, U., Hall, J., Jones, M., Linden, D., Owen, M. and Van Den Bree, M. 2020. Sleep problems and associations with psychopathology and cognition in young people with 22q11.2 deletion syndrome (22q11.2DS). Psychological Medicine 50, pp. 1191-1202. (10.1017/S0033291719001119)
- Clifton, N. E., Thomas, K. L., Wilkinson, L. S., Hall, J. and Trent, S. 2020. FMRP and CYFIP1 at the synapse and their role in psychiatric vulnerability. Complex Psychiatry (10.1159/000506858)
2019
- Ranson, A., Broom, E., Powell, A., Chen, F., Major, G. and Hall, J. 2019. Top-down suppression of sensory cortex in an NMDAR hypofunction model of psychosis. Schizophrenia Bulletin 45(6), pp. 1349-1357. (10.1093/schbul/sby190)
- Underwood, J., Kendall, K., Berrett, J., Lewis, C., Anney, R., Van den Bree, M. and Hall, J. 2019. Autism spectrum disorder diagnosis in adults: phenotype and genotype findings from a clinically derived cohort. British Journal of Psychiatry 215(5), pp. 647-653. (10.1192/bjp.2019.30)
- Sykes, L. et al. 2019. Genetic variation in the psychiatric risk gene CACNA1C modulates reversal learning across species. Schizophrenia Bulletin 45(5), pp. 1024-1032. (10.1093/schbul/sby146)
- Plumbly, W., Brandon, N., Deeb, T. Z., Hall, J. and Harwood, A. J. 2019. L-type voltage-gated calcium channel regulation of in vitro human cortical neuronal networks. Scientific Reports 9, article number: 13810. (10.1038/s41598-019-50226-9)
- Silva, A. I. et al. 2019. Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility. Nature Communications 10, article number: 3455. (10.1038/s41467-019-11119-7)
- Moon, A., Brydges, N., Thomas, K. and Hall, J. 2019. Su13: Genetic variation in 'calcium voltage-gated channel subunit alpha1c (cacna1c): interactions with prepubertal stress and impact on hippocampal dependent learning. European Neuropsychopharmacology 29(S4), pp. S1274-S1275. (10.1016/j.euroneuro.2018.08.377)
- Underwood, J., Kendall, K., Berrett, J., Anney, R., Bree, M. V. D. and Hall, J. 2019. SA20COPY Number variants and polygenic risk scores in adults with autism spectrum disorder (ASD): results from the NCMH adult ASD cohort. European Neuropsychopharmacology 29(S4), pp. S1198-S1199. (10.1016/j.euroneuro.2018.08.242)
- Jones, H. J., Hubbard, L., Mitchell, R. E., Jones, S. A., Williams, N. M., Zammit, S. and Hall, J. 2019. Association of genetic risk for rheumatoid arthritis with cognitive and psychiatric phenotypes across childhood and adolescence. JAMA Network Open 2(6), pp. -., article number: e196118. (10.1001/jamanetworkopen.2019.6118)
- Trent, S., Hall, J., Connelly, W. M. and Errington, A. C. 2019. Cyfip1 haploinsufficiency does not alter GABAA receptor δ-subunit expression and tonic inhibition in dentate gyrus PV+ interneurons and granule cells. eNeuro 6(3), article number: ENEURO.0364-18.2019. (10.1523/ENEURO.0364-18.2019)
- Cunningham, A. et al. 2019. Using kinematic analyses to explore sensorimotor control impairments in children with 22q11.2 deletion Syndrome. Journal of Neurodevelopmental Disorders 11, article number: 8. (10.1186/s11689-019-9271-3)
- Clifton, N., Trent, S., Thomas, K. and Hall, J. 2019. Regulation and function of activity-dependent Homer in synaptic plasticity. Molecular Neuropsychiatry 5(3), pp. 147-161. (10.1159/000500267)
- Chawner, S. J. R. A. et al. 2019. Genotype–phenotype associations in children with copy number variants associated with high neuropsychiatric risk in the UK (IMAGINE-ID): a case-control cohort study. Lancet Psychiatry 6(6), pp. 493 - 505. (10.1016/S2215-0366(19)30123-3)
- Srinivasan, R., Wolstencroft, J., Erwood, M., Raymond, F. L., Van Den Bree, M., Hall, J. and Skuse, D. 2019. Mental health and behavioural problems in children with XXYY: a comparison with intellectual disabilities. Journal of Intellectual Disability Research 63(5), pp. 477-488. (10.1111/jir.12607)
- Silva, A. I. et al. 2019. Reciprocal white matter changes associated with copy number variation at 15q11.2 BP1-BP2: A diffusion tensor imaging study. Biological Psychiatry 85(7), pp. 563-572. (10.1016/j.biopsych.2018.11.004)
- Lancaster, T. M. et al. 2019. Structural and functional neuroimaging of polygenic risk for schizophrenia: a recall-by-genotype-based approach. Schizophrenia Bulletin 45(2), pp. 405-414. (10.1093/schbul/sby037)
- Chawner, S., Owen, M. J., Holmans, P., Raymond, L., Skuse, D., Hall, J. and van den Bree, M. 2019. Genotype-phenotype relationships in children with copy number variants associated with high neuropsychiatric risk: Findings from the Intellectual Disability & Mental Health: Assessing the Genomic Impact on Neurodevelopment (IMAGINE-ID) study.. [Online]. BioRxiv. (10.1101/535708) Available at: https://doi.org/10.1101/535708
- Drakesmith, M. et al. 2019. Genetic risk for schizophrenia and developmental delay is associated with shape and microstructure of midline white-matter structures. Translational Psychiatry 9(1), article number: 102. (10.1038/s41398-019-0440-7)
- Clifton, N. E. et al. 2019. Dynamic expression of genes associated with schizophrenia and bipolar disorder across development. Translational Psychiatry 9, article number: 74. (10.1038/s41398-019-0405-x)
- Schwarz, E. et al. 2019. Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder. Translational Psychiatry 9(1), pp. -., article number: 12. (10.1038/s41398-018-0225-4)
- Niarchou, M. et al. 2019. Psychiatric disorders in children with 16p11.2 deletion and duplication. Translational Psychiatry (10.1038/s41398-018-0339-8)
- Melendez-Torres, G. et al. 2019. Measurement invariance properties and external construct validity of the Short Warwick-Edinburgh Mental Wellbeing Scale in a large national sample of secondary school students in Wales. Health and Quality of Life Outcomes 17, article number: 139. (10.1186/s12955-019-1204-z)
2018
- Brydges, N. M., Moon, A., Rule, L., Watkin, H., Thomas, K. L. and Hall, J. 2018. Sex specific effects of pre-pubertal stress on hippocampal neurogenesis and behaviour. Translational Psychiatry 8, article number: 271. (10.1038/s41398-018-0322-4)
- Sykes, L., Clifton, N., Hall, J. and Thomas, K. L. 2018. Regulation of the expression of the psychiatric risk gene Cacna1c during associative learning. Molecular Neuropsychiatry 4, pp. 149-157. (10.1159/000493917)
- Iliescu, A. F., Hall, J., Wilkinson, L. S., Dwyer, D. M. and Honey, R. C. 2018. The nature of phenotypic variation in Pavlovian conditioning. Journal of Experimental Psychology: Animal Learning and Cognition 44(4), pp. 358-369. (10.1037/xan0000177)
- Tigaret, C. M., Chamberlain, S. E. L., Sadowski, J. H. L. P., Hall, J., Ashby, M. C. and Mellor, J. R. 2018. Convergent metabotropic signalling pathways inhibit SK channels to promote synaptic plasticity in the hippocampus. Journal of Neuroscience 38(43), pp. 9252-9262. (10.1523/JNEUROSCI.1160-18.2018)
- Moon, A. L., Haan, N., Wilkinson, L. S., Thomas, K. L. and Hall, J. 2018. CACNA1C: Association with pychiatric disorders, behavior, and neurogenesis. Schizophrenia Bulletin 44(5), pp. 958-965. (10.1093/schbul/sby096)
- Kamath, A. et al. 2018. Chromosome 17q12 duplications: Further delineation of the range of psychiatric and clinical phenotypes. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 177(5), pp. 520-528. (10.1002/ajmg.b.32643)
- Pratt, J. and Hall, J. 2018. Biomarkers in neuropsychiatry: a prospect for the twenty-first century?. Current Topics in Behavioral Neuroscience 40, pp. 3-10. (10.1007/7854_2018_58)
- Ruderfer, D. M. et al. 2018. Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes. Cell 173(7), pp. 1705-1715.e16. (10.1016/j.cell.2018.05.046)
- Reddaway, J., Doherty, J. L., Lancaster, T., Linden, D., Walters, J. T. and Hall, J. 2018. Genomic and imaging biomarkers in schizophrenia. In: Current Topics in Behavioral Neurosciences. Berlin and Heidelberg: Springer, pp. 325-352., (10.1007/7854_2018_52)
- Clifton, N., Thomas, K. and Hall, J. 2018. The effect of ketamine on the consolidation and extinction of contextual fear memory. Journal of Psychopharmacology 32(2), pp. 156-162. (10.1177/0269881117748903)
- Cunningham, A. C. et al. 2018. Developmental coordination disorder, psychopathology and IQ in 22q11.2 deletion syndrome. British Journal of Psychiatry 212(1), pp. 27-33. (10.1192/bjp.2017.6)
2017
- Clifton, N., Cameron, D., Trent, S., Sykes, L. H., Thomas, K. L. and Hall, J. 2017. Hippocampal regulation of postsynaptic density Homer1 by associative learning. Neural Plasticity 2017, article number: 5959182. (10.1155/2017/5959182)
- Stanfield, A. M., Philip, R. C. M., Whalley, H., Romaniuk, L., Hall, J., Johnstone, E. C. and Lawrie, S. M. 2017. Dissociation of brain activation in autism and schizotypal personality disorder during social judgements. Schizophrenia Bulletin 43(6), pp. 1220-1228. (10.1093/schbul/sbx083)
- Schmaal, L. et al. 2017. Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group. Molecular Psychiatry 22(6), pp. 900-909. (10.1038/mp.2016.60)
- Neilson, E. et al. 2017. Effects of environmental risks and polygenic loading for schizophrenia on cortical thickness. Schizophrenia Research 184, pp. 128-136. (10.1016/j.schres.2016.12.011)
- Clifton, N. E. et al. 2017. Schizophrenia copy number variants and associative learning. Molecular Psychiatry 22(2), pp. 178-182. (10.1038/mp.2016.227)
- Foley, S. F. et al. 2017. Multimodal brain imaging reveals structural differences in Alzheimer's disease polygenic risk carriers: A study in healthy young adults. Biological Psychiatry 81(2), pp. 154-161. (10.1016/j.biopsych.2016.02.033)
- Trent, S., Phillip, B., Hall, J. and Thomas, K. 2017. AMPA receptors control fear extinction through an Arc-dependent mechanism. Learning and Memory 24, pp. 375-380. (10.1101/lm.045013.117)
- Radtke, F., Chapman, G., Hall, J. and Syed, Y. A. 2017. Modulating neuroinflammation to treat neuropsychiatric disorders. BioMed Research International, article number: 5071786.
- Hall, J. H. and Harwood, J. L. 2017. Brain lipids in health and disease. In: Food Lipids: Chemistry, Nutrition, and Biotechnology, Fourth Edition. CRC Press, pp. 747-764.
2016
- Chan, S. W. et al. 2016. Deactivation in anterior cingulate cortex during facial processing in young individuals with high familial risk and early development of depression: fMRI findings from the Scottish Bipolar Family Study. Journal of Child Psychology and Psychiatry 57(11), pp. 1277-1286. (10.1111/jcpp.12591)
- Thomson, P. A. et al. 2016. Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function. npj Schizophrenia 2, article number: 16024. (10.1038/npjschz.2016.24)
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2014
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Gwefannau
- Chawner, S., Owen, M. J., Holmans, P., Raymond, L., Skuse, D., Hall, J. and van den Bree, M. 2019. Genotype-phenotype relationships in children with copy number variants associated with high neuropsychiatric risk: Findings from the Intellectual Disability & Mental Health: Assessing the Genomic Impact on Neurodevelopment (IMAGINE-ID) study.. [Online]. BioRxiv. (10.1101/535708) Available at: https://doi.org/10.1101/535708
Research
Current Research Projects
- Role of psychiatric risk genes in learning and memory
- Expression and regulation of autism and schizophrenia associated genes
- Modulatory effects of early life experience on gene expression and psychiatric risk
- Genetic effects on brain function and structure
Supervisions
Current supervision
Jack Underwood
Wellcome Trust GW4-CAT Clinical Research Fellow, NMHRI
Contact Details
+44 29206 88342
Hadyn Ellis Building, Room 3.35, Maindy Road, Cardiff, CF24 4HQ
Research themes
Specialisms
- Schizophrenia
- Huntington's disease
- Autism
- Neurosciences
- Psychiatry