![James Lewis](https://profiles-cardiff.imgix.net/attachments/5980?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Professor James Lewis
(he/him)
Professor
- Available for postgraduate supervision
Overview
I am a professor in the School of Social Sciences, and a statistician and epidemiologist by training. My research is focused on better understanding public health challenges and designing and evaluating relevant interventions.
From March 2018 to September 2023 I was the director of Cardiff University's Y Lab - the Public Services Innovation Lab for Wales. At Y Lab we supported and promoted experimentation and innovation in public services in Wales, and conducted research on the hows and whys of public services innovation. Please see our website ylab.wales for more details.
Prior to this, I worked as a statistician and epidemiologist at the London School of Hygiene & Tropical Medicine for 12 years. I conducted research in global health, focusing on pragmatic evaluations of health system innovations across a range of disease areas and geographies. I lived in Johannesburg for seven years.
Publication
2024
- Khan, P. Y. et al. 2024. Insights into tuberculosis burden in Karachi, Pakistan: A concurrent adult tuberculosis prevalence and child Mycobacterium tuberculosis infection survey. PLOS Global Public Health 4(8), article number: e0002155. (10.1371/journal.pgph.0002155)
- O'Connor, C., Leyritana, K., Doyle, A. M., Lewis, J. J. and Salvaña, E. M. 2024. Changes in adherence and viral load suppression among people with HIV in Manila: Outcomes of the Philippines Connect for Life Study. AIDS and Behavior 28(3), pp. 837-853. (10.1007/s10461-023-04190-1)
2023
- Mutale, W. et al. 2023. Protocol-driven primary care and community linkage to reduce all-cause mortality in rural Zambia: a stepped-wedge cluster randomized trial. Frontiers in Public Health 11, article number: 1214066. (10.3389/fpubh.2023.1214066)
- Irfan, M., Buckley, K., Cheung, S. Y., Lewis, J., Koj, A. and Thomas, H. 2023. Mapping social capital across Wales (UK) using secondary data and spatial analysis. SN Social Sciences 3, article number: 56. (10.1007/s43545-023-00639-1)
2022
- O'Connor, C., Leyritana, K., Doyle, A. M., Birdthistle, I., Lewis, J. J., Gill, R. and Salvaña, E. M. 2022. Delivering an mHealth adherence support intervention for patients with HIV: Mixed methods process evaluation of the Philippines connect for life study. JMIR Formative Research 6(8), article number: e37163. (10.2196/37163)
- O'Connor, C., Leyritana, K., Doyle, A. M., Lewis, J. J., Gill, R. and Salvaña, E. M. 2022. Interactive mobile phone HIV adherence support for men who have sex with men in the Philippines connect for life study: mixed methods approach to intervention development and pilot testing. JMIR Formative Research 6(2), article number: e30811. (10.2196/30811)
- Hardyman, W., Garner, S., Lewis, J. J., Callaghan, R., Williams, E., Dalton, A. and Turner, A. 2022. Enhancing public service innovation through value co-creation: capacity building and the 'innovative imagination’. Public Money and Management 42(5), pp. 332-340.
2021
- Sarrassat, S., Lewis, J. J., Some, A. S., Somda, S., Cousens, S. and Blanchet, K. 2021. An Integrated eDiagnosis Approach (IeDA) versus standard IMCI for assessing and managing childhood illness in Burkina Faso: a stepped-wedge cluster randomised trial. BMC Health Services Research 21, article number: 354. (10.1186/s12913-021-06317-3)
- Velen, K. et al. 2021. Performance of GeneXpert MTB/RIF for diagnosing tuberculosis among symptomatic household contacts of index patients in South Africa. Open Forum Infectious Diseases 8(4), article number: ofab025. (10.1093/ofid/ofab025)
- O’Connor, C., Leyritana, K., Calica, K., Gill, R., Doyle, A. M., Lewis, J. J. and Salvaña, E. M. 2021. Risk factors affecting adherence to antiretroviral therapy among HIV patients in Manila, Philippines: a baseline cross-sectional analysis of the Philippines Connect for Life Study. Sexual Health 18(1), pp. 95-103. (10.1071/SH20028)
2020
- Izzo, A. A., Chimoyi, L., Velen, K., Churchyard, G. J., Wallis, R., Lewis, J. J. and Charalambous, S. 2020. An ecological study to evaluate the association of Bacillus Calmette-Guerin (BCG) vaccination on cases of SARS-CoV2 infection and mortality from COVID-19. PLoS ONE 15(12), article number: e0243707. (10.1371/journal.pone.0243707)
- Stagg, H. R., Lewis, J. J., Liu, X., Huan, S., Jiang, S., Chin, D. P. and Fielding, K. L. 2020. Temporal factors and missed doses of tuberculosis treatment: a causal associations approach to analyses of digital adherence data. Annals of the American Thoracic Society 17(4), pp. 438-449. (10.1513/AnnalsATS.201905-394OC)
2019
- Hargreaves, J. R., Hassan, S., Schellenberg, J., Hayes, R., Webster, J. and Lewis, J. J. 2019. Five challenges in the design and conduct of IS trials for HIV prevention and treatment. Journal of Acquired Immune Deficiency Syndromes 82, pp. S261-S270. (10.1097/QAI.0000000000002192)
- Williams, A., Rushton, A., Lewis, J. and Phillips, C. 2019. Evaluation of the clinical effectiveness of a work-based mentoring programme to develop clinical reasoning on patient outcome: A stepped wedge cluster randomised controlled trial. PLoS ONE 14(7), article number: e0220110. (10.1371/journal.pone.0220110)
- Hensen, B. et al. 2019. Application of an HIV prevention cascade to identify gaps in increasing coverage of voluntary medical male circumcision services in 42 rural Zambian communities. AIDS and Behavior 23(5), pp. 1095-1103. (10.1007/s10461-019-02407-w)
2018
- Lewis, J. J. et al. 2018. Evaluation of a medication monitor-based treatment strategy for drug-sensitive tuberculosis patients in China: study protocol for a cluster randomised controlled trial. Trials 19, pp. -., article number: 398. (10.1186/s13063-018-2650-3)
- Page-Shipp, L. et al. 2018. Household point of care CD4 testing and isoniazid preventive therapy initiation in a household TB contact tracing programme in two districts of South Africa. PLoS ONE 13(3), article number: e0192089. (10.1371/journal.pone.0192089)
2017
- Mastropasqua, R., Luo, Y. H., Cheah, Y. S., Egan, C., Lewis, J. J. and da Cruz, L. 2017. Black patients sustain vision loss while White and South Asian patients gain vision following delamination or segmentation surgery for tractional complications associated with proliferative diabetic retinopathy. Eye 31(10), pp. 1468-1474. (10.1038/eye.2017.95)
- Wingfield, T. et al. 2017. Socioeconomic support to improve initiation of tuberculosis preventive therapy and increase tuberculosis treatment success in Peru: a household-randomised, controlled evaluation. Lancet 389, pp. 16-16.
- Wingfield, T. et al. 2017. A randomized controlled study of socioeconomic support to enhance tuberculosis prevention and treatment, Peru. Bulletin of the World Health Organization 95, pp. 270-280. (10.2471/BLT.16.170167)
2016
- Greenland, K. et al. 2016. Multiple behaviour change intervention for diarrhoea control in Lusaka, Zambia: a cluster randomised trial. Lancet Global Health 4(12), pp. e966-e977. (10.1016/S2214-109X(16)30262-5)
- Kliemann, B. S., Levin, A. S., Luisa Moura, M., Boszczowski, I. and Lewis, J. J. 2016. Socioeconomic determinants of antibiotic consumption in the state of Sao Paulo, Brazil: The effect of restricting over-the-counter sales. PLoS ONE 11(12), pp. -., article number: e0167885. (10.1371/journal.pone.0167885)
- Wingfield, T. et al. 2016. The economic effects of supporting tuberculosis-affected households in Peru. European Respiratory Journal 48(5), pp. 1396-1410. (10.1183/13993003.00066-2016)
- Blanchet, K. et al. 2016. A mixed methods protocol to evaluate the effect and cost-effectiveness of an Integrated electronic Diagnosis Approach (IeDA) for the management of childhood illnesses at primary health facilities in Burkina Faso. Implementation Science 11, pp. -., article number: 111. (10.1186/s13012-016-0476-5)
- Jha, S. et al. 2016. Cost-effectiveness of automated digital microscopy for diagnosis of active tuberculosis. PLoS ONE 11(6), pp. -., article number: e0157554. (10.1371/journal.pone.0157554)
- Velen, K., Lewis, J. J., Charalambous, S., Page-Shipp, L., Popane, F., Churchyard, G. J. and Hoffmann, C. J. 2016. Household HIV testing uptake among contacts of TB patients in South Africa. PLoS ONE 11(5), pp. -., article number: e0155688. (10.1371/journal.pone.0155688)
- Hermans, S. M., Grant, A. D., Chihota, V., Lewis, J. J., Vynnycky, E., Churchyard, G. J. and Fielding, K. L. 2016. The timing of tuberculosis after isoniazid preventive therapy among gold miners in South Africa: a prospective cohort study. BMC Medicine 14, pp. -., article number: 45. (10.1186/s12916-016-0589-3)
2015
- Ononge, S., Campbell, O. M. R., Kaharuza, F., Lewis, J. J., Fielding, K. and Mirembe, F. 2015. Effectiveness and safety of misoprostol distributed to antenatal women to prevent postpartum haemorrhage after child-births: a stepped-wedge cluster-randomized trial. BMC Pregnancy and Childbirth 15, pp. -., article number: 315. (10.1186/s12884-015-0750-6)
- Hensen, B. et al. 2015. Frequency of HIV-testing and factors associated with multiple lifetime HIV-testing among a rural population of Zambian men. BMC Public Health 15, article number: 960. (10.1186/s12889-015-2259-3)
- Liu, X. et al. 2015. Effectiveness of electronic reminders to improve medication adherence in tuberculosis patients: a cluster-randomised trial. PLoS Medicine 12(9), article number: e1001876. (10.1371/journal.pmed.1001876)
- van Halsema, C. L., Fielding, K. L., Chihota, V. N., George, E. C., Lewis, J. J., Churchyard, G. J. and Grant, A. D. 2015. The effect of antiretroviral therapy and CD4 count on markers of infectiousness in HIV-associated tuberculosis. Journal of Acquired Immune Deficiency Syndromes 70(1), pp. 104-108. (10.1097/QAI.0000000000000684)
- Wingfield, T. et al. 2015. Designing and implementing a socioeconomic intervention to enhance TB control: operational evidence from the CRESIPT project in Peru. BMC Public Health 15, pp. -., article number: 810. (10.1186/s12889-015-2128-0)
- Hargreaves, J. R. et al. 2015. Five questions to consider before conducting a stepped wedge trial. Trials 16, article number: 350. (10.1186/s13063-015-0841-8)
- Copas, A. J., Lewis, J. J., Thompson, J. A., Davey, C., Baio, G. and Hargreaves, J. R. 2015. Designing a stepped wedge trial: three main designs, carry-over effects and randomisation approaches. Trials 16, article number: 352. (10.1186/s13063-015-0842-7)
- Prost, A. et al. 2015. Logistic, ethical, and political dimensions of stepped wedge trials: critical review and case studies. Trials 16, pp. -., article number: 351. (10.1186/s13063-015-0837-4)
- Beard, E. et al. 2015. Stepped wedge randomised controlled trials: systematic review of studies published between 2010 and 2014. Trials 16, pp. -., article number: 353. (10.1186/s13063-015-0839-2)
- Davey, C., Hargreaves, J., Thompson, J. A., Copas, A. J., Beard, E., Lewis, J. J. and Fielding, K. L. 2015. Analysis and reporting of stepped wedge randomised controlled trials: synthesis and critical appraisal of published studies, 2010 to 2014. Trials 16, pp. -., article number: 358. (10.1186/s13063-015-0838-3)
- Ismail, N. A. et al. 2015. Performance of a novel algorithm using automated digital microscopy for diagnosing tuberculosis. American Journal of Respiratory and Critical Care Medicine 191(12), pp. 1443-1449. (10.1164/rccm.201502-0390OC)
- Vynnycky, E. et al. 2015. Tuberculosis control in South African gold mines: Mathematical modeling of a trial of community-wide isoniazid preventive therapy. American Journal of Epidemiology 181(8), pp. 619-632. (10.1093/aje/kwu320)
- Hensen, B. et al. 2015. Factors associated with HIV-testing and acceptance of an offer of home-based testing by men in rural Zambia. AIDS and Behavior 19(3), pp. 492-504. (10.1007/s10461-014-0866-0)
- Mathema, B. et al. 2015. Molecular epidemiology of Mycobacterium tuberculosis among South African gold miners. Annals of the American Thoracic Society 12(1), pp. 12-20. (10.1513/AnnalsATS.201404-150OC)
- van Halsema, C. L. et al. 2015. Clinical relevance of nontuberculous mycobacteria isolated from sputum in a gold mining workforce in South Africa: an observational, clinical study. BioMed Research International 2015, article number: 959107. (10.1155/2015/959107)
2014
- Mutale, W. et al. 2014. Application of balanced scorecard in the evaluation of a complex health system intervention: 12 months post intervention findings from the BHOMA intervention: A cluster randomised trial in Zambia. PLoS ONE 9(4), article number: e93977. (10.1371/journal.pone.0093977)
- Ferguson, L. et al. 2014. Linking women who test HIV-positive in pregnancy-related services to HIV care and treatment services in Kenya: a mixed methods prospective cohort study. PLoS ONE 9(3), article number: e89764. (10.1371/journal.pone.0089764)
- Wingfield, T. et al. 2014. The seasonality of tuberculosis, sunlight, vitamin D, and household crowding. The Journal of Infectious Diseases 210(5), pp. 774-783. (10.1093/infdis/jiu121)
- Smith, J. et al. 2014. The distribution of sex acts and condom use within partnerships in a rural sub-Saharan African population. PLoS ONE 9(2), article number: e88378. (10.1371/journal.pone.0088378)
- Churchyard, G. J. et al. 2014. A trial of mass isoniazid preventive therapy for tuberculosis control. New England Journal of Medicine 370(4), pp. 301-310. (10.1056/NEJMoa1214289)
2013
- Marais, E. et al. 2013. Treatment outcomes of multidrug-resistant tuberculosis patients in Gauteng, South Africa. Infection 42(2), pp. 405-413. (10.1007/s15010-013-0572-2)
- Lewis, J. J. et al. 2013. Eligibility for isoniazid preventive therapy in South African gold mines. PLoS ONE 8(11), article number: e81376. (10.1371/journal.pone.0081376)
- Letang, E. et al. 2013. Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma. AIDS 27(10), pp. 1603-1613. (10.1097/qad.0b013e328360a5a1)
- Hensen, B., Taoka, S., Lewis, J. J., Weiss, H. A. and Hargreaves, J. 2013. Systematic review of strategies to increase men's HIV-testing in sub-Saharan Africa. AIDS 28(14), pp. 2133-2145. (10.1097/QAD.0000000000000395)
- Velen, K., Lewis, J. J., Charalambous, S., Grant, A. D., Churchyard, G. J. and Hoffmann, C. J. 2013. Comparison of Tenofovir, Zidovudine, or Stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study. PLoS ONE 8(5), article number: e64459. (10.1371/journal.pone.0064459)
- Hoffmann, C. J. et al. 2013. Mortality associated with delays between clinic entry and ART initiation in resource-limited settings. Journal of Acquired Immune Deficiency Syndromes 63(1), pp. 105-111. (10.1097/QAI.0b013e3182893fb4)
2012
- Lewis, J. J. et al. 2012. "Proof-of-concept" Evaluation of an automated sputum smear microscopy system for tuberculosis diagnosis. PLoS ONE 7(11) (10.1371/journal.pone.0050173)
- Dorman, S. E. et al. 2012. Performance characteristics of the Cepheid Xpert MTB/RIF test in a tuberculosis prevalence survey. PLoS ONE 7(8), article number: e43307. (10.1371/journal.pone.0043307)
- Ferguson, L., Lewis, J., Grant, A. D., Watson-Jones, D., Vusha, S., Ong'ech, J. O. and Ross, D. A. 2012. Patient attrition between diagnosis with HIV in pregnancy-related services and long-term HIV care and treatment services in Kenya. Journal of Acquired Immune Deficiency Syndrome 60(3), pp. e90-e97. (10.1097/QAI.0b013e318253258a)
- van Halsema, C. L., Fielding, K. L., Chihota, V. N., Lewis, J. J., Churchyard, G. J. and Grant, A. D. 2012. Trends in drug-resistant tuberculosis in a gold-mining workforce in South Africa, 2002-2008. International Journal of Tuberculosis and Lung Disease 16(7), pp. 967-973. (10.5588/ijtld.11.0122)
- Dorman, S. E. et al. 2012. Genotype MTBDR plus for direct detection of mycobacterium tuberculosis and drug resistance in strains from gold miners in South Africa. Journal of Clinical Microbiology 50(4), pp. 1189-1194. (10.1128/JCM.05723-11)
2011
- Kranzer, K. et al. 2011. Antiretroviral treatment cohort analysis using time-updated CD4 counts: assessment of bias with different analytic methods. PLoS ONE 6(11), article number: e27763. (10.1371/journal.pone.0027763)
2010
- Grant, A. D. et al. 2010. 'Team up against TB': promoting involvement in Thibela TB, a trial of community-wide tuberculosis preventive therapy. AIDS 24(Suppl), pp. s37-s44. (10.1097/01.aids.0000391020.10661.eb)
- Churchyard, G. J., Fielding, K. L., Lewis, J. J., Chihota, V. N., Hanifa, Y. and Grant, A. D. 2010. Symptom and chest radiographic screening for infectious tuberculosis prior to starting isoniazid preventive therapy: yield and proportion missed at screening. AIDS 24(Suppl), pp. S19-S27. (10.1097/01.aids.0000391018.72542.46)
- Kranzer, K. et al. 2010. Treatment interruption in a primary care antiretroviral therapy program in South Africa: cohort analysis of trends and risk factors. Journal of Acquired Immune Deficiency Syndrome 55(3), pp. e17-e23. (10.1097/QAI.0b013e3181f275fd)
- Lawn, S. D., Wood, R., De Cock, K. M., Kranzer, K., Lewis, J. J. and Churchyard, G. J. 2010. Antiretrovirals and isoniazid preventive therapy in the prevention of HIV-associated tuberculosis in settings with limited health-care resources. The Lancet Infectious Diseases 10(7), pp. 489-498. (10.1016/S1473-3099(10)70078-5)
- van Halsema, C. L., Fielding, K. L., Chihota, V. N., Russell, E. C., Lewis, J. J., Churchyard, G. J. and Grant, A. D. 2010. Tuberculosis outcomes and drug susceptibility in individuals exposed to isoniazid preventive therapy in a high HIV prevalence setting. AIDS 24(7), pp. 1051-1055. (10.1097/QAD.0b013e32833849df)
2009
- Lewis, J. J. et al. 2009. HIV infection does not affect active case finding of tuberculosis in South African gold miners. American Journal of Respiratory and Critical Care Medicine 180(12), pp. 1165-1281. (10.1164/rccm.200806-846OC)
- Hanifer, Y., Grant, A., Lewis, J., Corbett, E., Fielding, K. and Churchyard, G. 2009. Prevalence of latent tuberculosis infection among gold miners in South Africa. International Journal of Tuberculosis and Lung Disease 13(1), pp. 39-46.
2007
- Lopman, B., Lewis, J., Nyamukapa, C., Mushati, P., Chandiwana, S. and Gregson, S. 2007. HIV incidence and poverty in Manicaland, Zimbabwe: is HIV becoming a disease of the poor?. AIDS 21(Suppl), pp. S57-S66. (10.1097/01.aids.0000300536.82354.52)
- Hanifa, Y., Mngadi, K., Lewis, J., Fielding, K., Churchyard, G. and Grant, A. 2007. Evaluation of the Arkansas method of urine testing for isoniazid in South Africa. International Journal of Tuberculosis and Lung Disease 11(11), pp. 1232-1236.
- Hallett, T. B. et al. 2007. Age at first sex and HIV infection in rural Zimbabwe. Studies in Family Planning 38(1), pp. 1-10. (10.1111/j.1728-4465.2007.00111.x)
- Hallett, T. B., Gregson, S., Lewis, J. J. C., Lopman, B. A. and Garnett, G. P. 2007. Behaviour change in generalised HIV epidemics: impact of reducing cross-generational sex and delaying age at sexual debut. Sexually Transmitted Infections 83(suppl), pp. i50-i54. (10.1136/sti.2006.023606)
- Lewis, J. J. C., Donnelly, C. A., Mare, P., Mupambireyi, Z., Garnett, G. P. and Gregson, S. 2007. Evaluating the proximate determinants framework for HIV infection in rural Zimbabwe. Sexually Transmitted Infections 83(suppl), pp. i61-i69. (10.1136/sti.2006.023671)
2006
- Gregson, S. et al. 2006. HIV decline associated with behavior change in Eastern Zimbabwe. Science 311(5761), pp. 664-666. (10.1126/science.1121054)
2005
- Lewis, J. J. C., Garnett, G. P., Nyamukapa, C. A., Donnelly, C. A., Mason, P. R. and Gregson, S. 2005. Patterns of uptake of treatment for self reported sexually transmitted infection symptoms in rural Zimbabwe. Sexually Transmitted Infections 81(4), pp. 326-332. (10.1136/sti.2004.012773)
- Lewis, J. J., Garnett, G. P., Mhlanga, S., Nyamukapa, C. A., Donnelly, C. A. and Gregson, S. 2005. Beer halls as a focus for HIV prevention activities in rural Zimbabwe. Sexually Transmitted Diseases 32(6), pp. 364-369. (10.1097/01.olq.0000154506.84492.61)
2004
- Lewis, J. J., Ronsmans, C., Ezeh, A. and Gregson, S. 2004. The population impact of HIV on fertility in sub-Saharan Africa. AIDS 18(Supp), pp. S35-S43. (10.1097/00002030-200406002-00005)
- Salek, M., Finlay, A., Lewis, J. and Sumner, M. 2004. Quality of life improvement in treatment of psoriasis with intermittent short course Cyclosporin (Neoral®). Quality of Life Research 13(1), pp. 91-95. (10.1023/B:QURE.0000015293.69661.ff)
- Grassly, N., Lewis, J., Mahy, M., Walker, N. and Timæus, I. 2004. Comparison of household-survey estimates with projections of mortality and orphan numbers in sub-Saharan Africa in the era of HIV/AIDS. Population Studies 58(2), pp. 207-217. (10.1080/0032472042000224431)
2003
- Becker, N. G., Lewis, J. J. C., Li, Z. and McDonald, A. 2003. Age-specific back-projection of HIV diagnosis data. Statistics in Medicine 22(13), pp. 2177-2190. (10.1002/sim.1406)
1995
- Gregson, S. et al. 1995. HIV infection and reproductive health in teenage women orphaned and made vulnerable by AIDS in Zimbabwe. AIDS Care 17(7), pp. 785-794. (10.1080/09540120500258029)
Articles
- Khan, P. Y. et al. 2024. Insights into tuberculosis burden in Karachi, Pakistan: A concurrent adult tuberculosis prevalence and child Mycobacterium tuberculosis infection survey. PLOS Global Public Health 4(8), article number: e0002155. (10.1371/journal.pgph.0002155)
- O'Connor, C., Leyritana, K., Doyle, A. M., Lewis, J. J. and Salvaña, E. M. 2024. Changes in adherence and viral load suppression among people with HIV in Manila: Outcomes of the Philippines Connect for Life Study. AIDS and Behavior 28(3), pp. 837-853. (10.1007/s10461-023-04190-1)
- Mutale, W. et al. 2023. Protocol-driven primary care and community linkage to reduce all-cause mortality in rural Zambia: a stepped-wedge cluster randomized trial. Frontiers in Public Health 11, article number: 1214066. (10.3389/fpubh.2023.1214066)
- Irfan, M., Buckley, K., Cheung, S. Y., Lewis, J., Koj, A. and Thomas, H. 2023. Mapping social capital across Wales (UK) using secondary data and spatial analysis. SN Social Sciences 3, article number: 56. (10.1007/s43545-023-00639-1)
- O'Connor, C., Leyritana, K., Doyle, A. M., Birdthistle, I., Lewis, J. J., Gill, R. and Salvaña, E. M. 2022. Delivering an mHealth adherence support intervention for patients with HIV: Mixed methods process evaluation of the Philippines connect for life study. JMIR Formative Research 6(8), article number: e37163. (10.2196/37163)
- O'Connor, C., Leyritana, K., Doyle, A. M., Lewis, J. J., Gill, R. and Salvaña, E. M. 2022. Interactive mobile phone HIV adherence support for men who have sex with men in the Philippines connect for life study: mixed methods approach to intervention development and pilot testing. JMIR Formative Research 6(2), article number: e30811. (10.2196/30811)
- Hardyman, W., Garner, S., Lewis, J. J., Callaghan, R., Williams, E., Dalton, A. and Turner, A. 2022. Enhancing public service innovation through value co-creation: capacity building and the 'innovative imagination’. Public Money and Management 42(5), pp. 332-340.
- Sarrassat, S., Lewis, J. J., Some, A. S., Somda, S., Cousens, S. and Blanchet, K. 2021. An Integrated eDiagnosis Approach (IeDA) versus standard IMCI for assessing and managing childhood illness in Burkina Faso: a stepped-wedge cluster randomised trial. BMC Health Services Research 21, article number: 354. (10.1186/s12913-021-06317-3)
- Velen, K. et al. 2021. Performance of GeneXpert MTB/RIF for diagnosing tuberculosis among symptomatic household contacts of index patients in South Africa. Open Forum Infectious Diseases 8(4), article number: ofab025. (10.1093/ofid/ofab025)
- O’Connor, C., Leyritana, K., Calica, K., Gill, R., Doyle, A. M., Lewis, J. J. and Salvaña, E. M. 2021. Risk factors affecting adherence to antiretroviral therapy among HIV patients in Manila, Philippines: a baseline cross-sectional analysis of the Philippines Connect for Life Study. Sexual Health 18(1), pp. 95-103. (10.1071/SH20028)
- Izzo, A. A., Chimoyi, L., Velen, K., Churchyard, G. J., Wallis, R., Lewis, J. J. and Charalambous, S. 2020. An ecological study to evaluate the association of Bacillus Calmette-Guerin (BCG) vaccination on cases of SARS-CoV2 infection and mortality from COVID-19. PLoS ONE 15(12), article number: e0243707. (10.1371/journal.pone.0243707)
- Stagg, H. R., Lewis, J. J., Liu, X., Huan, S., Jiang, S., Chin, D. P. and Fielding, K. L. 2020. Temporal factors and missed doses of tuberculosis treatment: a causal associations approach to analyses of digital adherence data. Annals of the American Thoracic Society 17(4), pp. 438-449. (10.1513/AnnalsATS.201905-394OC)
- Hargreaves, J. R., Hassan, S., Schellenberg, J., Hayes, R., Webster, J. and Lewis, J. J. 2019. Five challenges in the design and conduct of IS trials for HIV prevention and treatment. Journal of Acquired Immune Deficiency Syndromes 82, pp. S261-S270. (10.1097/QAI.0000000000002192)
- Williams, A., Rushton, A., Lewis, J. and Phillips, C. 2019. Evaluation of the clinical effectiveness of a work-based mentoring programme to develop clinical reasoning on patient outcome: A stepped wedge cluster randomised controlled trial. PLoS ONE 14(7), article number: e0220110. (10.1371/journal.pone.0220110)
- Hensen, B. et al. 2019. Application of an HIV prevention cascade to identify gaps in increasing coverage of voluntary medical male circumcision services in 42 rural Zambian communities. AIDS and Behavior 23(5), pp. 1095-1103. (10.1007/s10461-019-02407-w)
- Lewis, J. J. et al. 2018. Evaluation of a medication monitor-based treatment strategy for drug-sensitive tuberculosis patients in China: study protocol for a cluster randomised controlled trial. Trials 19, pp. -., article number: 398. (10.1186/s13063-018-2650-3)
- Page-Shipp, L. et al. 2018. Household point of care CD4 testing and isoniazid preventive therapy initiation in a household TB contact tracing programme in two districts of South Africa. PLoS ONE 13(3), article number: e0192089. (10.1371/journal.pone.0192089)
- Mastropasqua, R., Luo, Y. H., Cheah, Y. S., Egan, C., Lewis, J. J. and da Cruz, L. 2017. Black patients sustain vision loss while White and South Asian patients gain vision following delamination or segmentation surgery for tractional complications associated with proliferative diabetic retinopathy. Eye 31(10), pp. 1468-1474. (10.1038/eye.2017.95)
- Wingfield, T. et al. 2017. Socioeconomic support to improve initiation of tuberculosis preventive therapy and increase tuberculosis treatment success in Peru: a household-randomised, controlled evaluation. Lancet 389, pp. 16-16.
- Wingfield, T. et al. 2017. A randomized controlled study of socioeconomic support to enhance tuberculosis prevention and treatment, Peru. Bulletin of the World Health Organization 95, pp. 270-280. (10.2471/BLT.16.170167)
- Greenland, K. et al. 2016. Multiple behaviour change intervention for diarrhoea control in Lusaka, Zambia: a cluster randomised trial. Lancet Global Health 4(12), pp. e966-e977. (10.1016/S2214-109X(16)30262-5)
- Kliemann, B. S., Levin, A. S., Luisa Moura, M., Boszczowski, I. and Lewis, J. J. 2016. Socioeconomic determinants of antibiotic consumption in the state of Sao Paulo, Brazil: The effect of restricting over-the-counter sales. PLoS ONE 11(12), pp. -., article number: e0167885. (10.1371/journal.pone.0167885)
- Wingfield, T. et al. 2016. The economic effects of supporting tuberculosis-affected households in Peru. European Respiratory Journal 48(5), pp. 1396-1410. (10.1183/13993003.00066-2016)
- Blanchet, K. et al. 2016. A mixed methods protocol to evaluate the effect and cost-effectiveness of an Integrated electronic Diagnosis Approach (IeDA) for the management of childhood illnesses at primary health facilities in Burkina Faso. Implementation Science 11, pp. -., article number: 111. (10.1186/s13012-016-0476-5)
- Jha, S. et al. 2016. Cost-effectiveness of automated digital microscopy for diagnosis of active tuberculosis. PLoS ONE 11(6), pp. -., article number: e0157554. (10.1371/journal.pone.0157554)
- Velen, K., Lewis, J. J., Charalambous, S., Page-Shipp, L., Popane, F., Churchyard, G. J. and Hoffmann, C. J. 2016. Household HIV testing uptake among contacts of TB patients in South Africa. PLoS ONE 11(5), pp. -., article number: e0155688. (10.1371/journal.pone.0155688)
- Hermans, S. M., Grant, A. D., Chihota, V., Lewis, J. J., Vynnycky, E., Churchyard, G. J. and Fielding, K. L. 2016. The timing of tuberculosis after isoniazid preventive therapy among gold miners in South Africa: a prospective cohort study. BMC Medicine 14, pp. -., article number: 45. (10.1186/s12916-016-0589-3)
- Ononge, S., Campbell, O. M. R., Kaharuza, F., Lewis, J. J., Fielding, K. and Mirembe, F. 2015. Effectiveness and safety of misoprostol distributed to antenatal women to prevent postpartum haemorrhage after child-births: a stepped-wedge cluster-randomized trial. BMC Pregnancy and Childbirth 15, pp. -., article number: 315. (10.1186/s12884-015-0750-6)
- Hensen, B. et al. 2015. Frequency of HIV-testing and factors associated with multiple lifetime HIV-testing among a rural population of Zambian men. BMC Public Health 15, article number: 960. (10.1186/s12889-015-2259-3)
- Liu, X. et al. 2015. Effectiveness of electronic reminders to improve medication adherence in tuberculosis patients: a cluster-randomised trial. PLoS Medicine 12(9), article number: e1001876. (10.1371/journal.pmed.1001876)
- van Halsema, C. L., Fielding, K. L., Chihota, V. N., George, E. C., Lewis, J. J., Churchyard, G. J. and Grant, A. D. 2015. The effect of antiretroviral therapy and CD4 count on markers of infectiousness in HIV-associated tuberculosis. Journal of Acquired Immune Deficiency Syndromes 70(1), pp. 104-108. (10.1097/QAI.0000000000000684)
- Wingfield, T. et al. 2015. Designing and implementing a socioeconomic intervention to enhance TB control: operational evidence from the CRESIPT project in Peru. BMC Public Health 15, pp. -., article number: 810. (10.1186/s12889-015-2128-0)
- Hargreaves, J. R. et al. 2015. Five questions to consider before conducting a stepped wedge trial. Trials 16, article number: 350. (10.1186/s13063-015-0841-8)
- Copas, A. J., Lewis, J. J., Thompson, J. A., Davey, C., Baio, G. and Hargreaves, J. R. 2015. Designing a stepped wedge trial: three main designs, carry-over effects and randomisation approaches. Trials 16, article number: 352. (10.1186/s13063-015-0842-7)
- Prost, A. et al. 2015. Logistic, ethical, and political dimensions of stepped wedge trials: critical review and case studies. Trials 16, pp. -., article number: 351. (10.1186/s13063-015-0837-4)
- Beard, E. et al. 2015. Stepped wedge randomised controlled trials: systematic review of studies published between 2010 and 2014. Trials 16, pp. -., article number: 353. (10.1186/s13063-015-0839-2)
- Davey, C., Hargreaves, J., Thompson, J. A., Copas, A. J., Beard, E., Lewis, J. J. and Fielding, K. L. 2015. Analysis and reporting of stepped wedge randomised controlled trials: synthesis and critical appraisal of published studies, 2010 to 2014. Trials 16, pp. -., article number: 358. (10.1186/s13063-015-0838-3)
- Ismail, N. A. et al. 2015. Performance of a novel algorithm using automated digital microscopy for diagnosing tuberculosis. American Journal of Respiratory and Critical Care Medicine 191(12), pp. 1443-1449. (10.1164/rccm.201502-0390OC)
- Vynnycky, E. et al. 2015. Tuberculosis control in South African gold mines: Mathematical modeling of a trial of community-wide isoniazid preventive therapy. American Journal of Epidemiology 181(8), pp. 619-632. (10.1093/aje/kwu320)
- Hensen, B. et al. 2015. Factors associated with HIV-testing and acceptance of an offer of home-based testing by men in rural Zambia. AIDS and Behavior 19(3), pp. 492-504. (10.1007/s10461-014-0866-0)
- Mathema, B. et al. 2015. Molecular epidemiology of Mycobacterium tuberculosis among South African gold miners. Annals of the American Thoracic Society 12(1), pp. 12-20. (10.1513/AnnalsATS.201404-150OC)
- van Halsema, C. L. et al. 2015. Clinical relevance of nontuberculous mycobacteria isolated from sputum in a gold mining workforce in South Africa: an observational, clinical study. BioMed Research International 2015, article number: 959107. (10.1155/2015/959107)
- Mutale, W. et al. 2014. Application of balanced scorecard in the evaluation of a complex health system intervention: 12 months post intervention findings from the BHOMA intervention: A cluster randomised trial in Zambia. PLoS ONE 9(4), article number: e93977. (10.1371/journal.pone.0093977)
- Ferguson, L. et al. 2014. Linking women who test HIV-positive in pregnancy-related services to HIV care and treatment services in Kenya: a mixed methods prospective cohort study. PLoS ONE 9(3), article number: e89764. (10.1371/journal.pone.0089764)
- Wingfield, T. et al. 2014. The seasonality of tuberculosis, sunlight, vitamin D, and household crowding. The Journal of Infectious Diseases 210(5), pp. 774-783. (10.1093/infdis/jiu121)
- Smith, J. et al. 2014. The distribution of sex acts and condom use within partnerships in a rural sub-Saharan African population. PLoS ONE 9(2), article number: e88378. (10.1371/journal.pone.0088378)
- Churchyard, G. J. et al. 2014. A trial of mass isoniazid preventive therapy for tuberculosis control. New England Journal of Medicine 370(4), pp. 301-310. (10.1056/NEJMoa1214289)
- Marais, E. et al. 2013. Treatment outcomes of multidrug-resistant tuberculosis patients in Gauteng, South Africa. Infection 42(2), pp. 405-413. (10.1007/s15010-013-0572-2)
- Lewis, J. J. et al. 2013. Eligibility for isoniazid preventive therapy in South African gold mines. PLoS ONE 8(11), article number: e81376. (10.1371/journal.pone.0081376)
- Letang, E. et al. 2013. Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma. AIDS 27(10), pp. 1603-1613. (10.1097/qad.0b013e328360a5a1)
- Hensen, B., Taoka, S., Lewis, J. J., Weiss, H. A. and Hargreaves, J. 2013. Systematic review of strategies to increase men's HIV-testing in sub-Saharan Africa. AIDS 28(14), pp. 2133-2145. (10.1097/QAD.0000000000000395)
- Velen, K., Lewis, J. J., Charalambous, S., Grant, A. D., Churchyard, G. J. and Hoffmann, C. J. 2013. Comparison of Tenofovir, Zidovudine, or Stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study. PLoS ONE 8(5), article number: e64459. (10.1371/journal.pone.0064459)
- Hoffmann, C. J. et al. 2013. Mortality associated with delays between clinic entry and ART initiation in resource-limited settings. Journal of Acquired Immune Deficiency Syndromes 63(1), pp. 105-111. (10.1097/QAI.0b013e3182893fb4)
- Lewis, J. J. et al. 2012. "Proof-of-concept" Evaluation of an automated sputum smear microscopy system for tuberculosis diagnosis. PLoS ONE 7(11) (10.1371/journal.pone.0050173)
- Dorman, S. E. et al. 2012. Performance characteristics of the Cepheid Xpert MTB/RIF test in a tuberculosis prevalence survey. PLoS ONE 7(8), article number: e43307. (10.1371/journal.pone.0043307)
- Ferguson, L., Lewis, J., Grant, A. D., Watson-Jones, D., Vusha, S., Ong'ech, J. O. and Ross, D. A. 2012. Patient attrition between diagnosis with HIV in pregnancy-related services and long-term HIV care and treatment services in Kenya. Journal of Acquired Immune Deficiency Syndrome 60(3), pp. e90-e97. (10.1097/QAI.0b013e318253258a)
- van Halsema, C. L., Fielding, K. L., Chihota, V. N., Lewis, J. J., Churchyard, G. J. and Grant, A. D. 2012. Trends in drug-resistant tuberculosis in a gold-mining workforce in South Africa, 2002-2008. International Journal of Tuberculosis and Lung Disease 16(7), pp. 967-973. (10.5588/ijtld.11.0122)
- Dorman, S. E. et al. 2012. Genotype MTBDR plus for direct detection of mycobacterium tuberculosis and drug resistance in strains from gold miners in South Africa. Journal of Clinical Microbiology 50(4), pp. 1189-1194. (10.1128/JCM.05723-11)
- Kranzer, K. et al. 2011. Antiretroviral treatment cohort analysis using time-updated CD4 counts: assessment of bias with different analytic methods. PLoS ONE 6(11), article number: e27763. (10.1371/journal.pone.0027763)
- Grant, A. D. et al. 2010. 'Team up against TB': promoting involvement in Thibela TB, a trial of community-wide tuberculosis preventive therapy. AIDS 24(Suppl), pp. s37-s44. (10.1097/01.aids.0000391020.10661.eb)
- Churchyard, G. J., Fielding, K. L., Lewis, J. J., Chihota, V. N., Hanifa, Y. and Grant, A. D. 2010. Symptom and chest radiographic screening for infectious tuberculosis prior to starting isoniazid preventive therapy: yield and proportion missed at screening. AIDS 24(Suppl), pp. S19-S27. (10.1097/01.aids.0000391018.72542.46)
- Kranzer, K. et al. 2010. Treatment interruption in a primary care antiretroviral therapy program in South Africa: cohort analysis of trends and risk factors. Journal of Acquired Immune Deficiency Syndrome 55(3), pp. e17-e23. (10.1097/QAI.0b013e3181f275fd)
- Lawn, S. D., Wood, R., De Cock, K. M., Kranzer, K., Lewis, J. J. and Churchyard, G. J. 2010. Antiretrovirals and isoniazid preventive therapy in the prevention of HIV-associated tuberculosis in settings with limited health-care resources. The Lancet Infectious Diseases 10(7), pp. 489-498. (10.1016/S1473-3099(10)70078-5)
- van Halsema, C. L., Fielding, K. L., Chihota, V. N., Russell, E. C., Lewis, J. J., Churchyard, G. J. and Grant, A. D. 2010. Tuberculosis outcomes and drug susceptibility in individuals exposed to isoniazid preventive therapy in a high HIV prevalence setting. AIDS 24(7), pp. 1051-1055. (10.1097/QAD.0b013e32833849df)
- Lewis, J. J. et al. 2009. HIV infection does not affect active case finding of tuberculosis in South African gold miners. American Journal of Respiratory and Critical Care Medicine 180(12), pp. 1165-1281. (10.1164/rccm.200806-846OC)
- Hanifer, Y., Grant, A., Lewis, J., Corbett, E., Fielding, K. and Churchyard, G. 2009. Prevalence of latent tuberculosis infection among gold miners in South Africa. International Journal of Tuberculosis and Lung Disease 13(1), pp. 39-46.
- Lopman, B., Lewis, J., Nyamukapa, C., Mushati, P., Chandiwana, S. and Gregson, S. 2007. HIV incidence and poverty in Manicaland, Zimbabwe: is HIV becoming a disease of the poor?. AIDS 21(Suppl), pp. S57-S66. (10.1097/01.aids.0000300536.82354.52)
- Hanifa, Y., Mngadi, K., Lewis, J., Fielding, K., Churchyard, G. and Grant, A. 2007. Evaluation of the Arkansas method of urine testing for isoniazid in South Africa. International Journal of Tuberculosis and Lung Disease 11(11), pp. 1232-1236.
- Hallett, T. B. et al. 2007. Age at first sex and HIV infection in rural Zimbabwe. Studies in Family Planning 38(1), pp. 1-10. (10.1111/j.1728-4465.2007.00111.x)
- Hallett, T. B., Gregson, S., Lewis, J. J. C., Lopman, B. A. and Garnett, G. P. 2007. Behaviour change in generalised HIV epidemics: impact of reducing cross-generational sex and delaying age at sexual debut. Sexually Transmitted Infections 83(suppl), pp. i50-i54. (10.1136/sti.2006.023606)
- Lewis, J. J. C., Donnelly, C. A., Mare, P., Mupambireyi, Z., Garnett, G. P. and Gregson, S. 2007. Evaluating the proximate determinants framework for HIV infection in rural Zimbabwe. Sexually Transmitted Infections 83(suppl), pp. i61-i69. (10.1136/sti.2006.023671)
- Gregson, S. et al. 2006. HIV decline associated with behavior change in Eastern Zimbabwe. Science 311(5761), pp. 664-666. (10.1126/science.1121054)
- Lewis, J. J. C., Garnett, G. P., Nyamukapa, C. A., Donnelly, C. A., Mason, P. R. and Gregson, S. 2005. Patterns of uptake of treatment for self reported sexually transmitted infection symptoms in rural Zimbabwe. Sexually Transmitted Infections 81(4), pp. 326-332. (10.1136/sti.2004.012773)
- Lewis, J. J., Garnett, G. P., Mhlanga, S., Nyamukapa, C. A., Donnelly, C. A. and Gregson, S. 2005. Beer halls as a focus for HIV prevention activities in rural Zimbabwe. Sexually Transmitted Diseases 32(6), pp. 364-369. (10.1097/01.olq.0000154506.84492.61)
- Lewis, J. J., Ronsmans, C., Ezeh, A. and Gregson, S. 2004. The population impact of HIV on fertility in sub-Saharan Africa. AIDS 18(Supp), pp. S35-S43. (10.1097/00002030-200406002-00005)
- Salek, M., Finlay, A., Lewis, J. and Sumner, M. 2004. Quality of life improvement in treatment of psoriasis with intermittent short course Cyclosporin (Neoral®). Quality of Life Research 13(1), pp. 91-95. (10.1023/B:QURE.0000015293.69661.ff)
- Grassly, N., Lewis, J., Mahy, M., Walker, N. and Timæus, I. 2004. Comparison of household-survey estimates with projections of mortality and orphan numbers in sub-Saharan Africa in the era of HIV/AIDS. Population Studies 58(2), pp. 207-217. (10.1080/0032472042000224431)
- Becker, N. G., Lewis, J. J. C., Li, Z. and McDonald, A. 2003. Age-specific back-projection of HIV diagnosis data. Statistics in Medicine 22(13), pp. 2177-2190. (10.1002/sim.1406)
- Gregson, S. et al. 1995. HIV infection and reproductive health in teenage women orphaned and made vulnerable by AIDS in Zimbabwe. AIDS Care 17(7), pp. 785-794. (10.1080/09540120500258029)
Research
@ylabwales we conducted research on public service innovation, including through several of our programmes, including:
- Innovate to Save
- Health, Arts, Research, People (HARP)
- Innovative Future Services (Infuse)
- Cardiff Capital Region Challenge Fund
The primary evaluation methodologies I have applied in global health have been cluster randomised trials and stepped wedge trials, always in interdisciplinary teams. I lived and worked in Johannesburg for seven years and I have also worked on projects in Peru, Burkina Faso, India, China, Zimbabwe and Zambia.
Teaching
Undergraduate
Lies, Damned Lies, and Statistics (Year 1, Module Convener 2023)
Knowing the Social World: Online and Offline Surveys (Year 2, Module Convener 2024)
Postgraduate
Evaluation: Developing and Evaluating Interventions in Complex Social Systems (MSc, Teaching 2023)
Biography
Education
2001 –2005: PhD in Epidemiology at Imperial College London. “Behavioural, demographic and social risk factors for HIV infection in rural Zimbabwe.” Received MRC funding.
1999 –2000: MSc in Applied Statistics at the University of Oxford. Grade: Distinction. Gutierrez Toscano prize for joint top result. Received EPSRC funding.
1996 – 1999: BA (Hons) in Mathematics at the University of Cambridge. Class: 2:1.
Professional memberships
Fellow of the Royal Geographical Society
Academic positions
2016 – 2018: Associate Professor, London School of Hygiene & Tropical Medicine. Based in London.
2013 – 2018: Deputy Director, Centre for Evaluation, London School of Hygiene & Tropical Medicine.
2013 – 2016: Senior Lecturer, London School of Hygiene & Tropical Medicine. Based in London.
2012 – 2013: Lecturer, London School of Hygiene & Tropical Medicine. Based in London.
2007 – 2012: Lecturer, London School of Hygiene & Tropical Medicine. Based at Aurum Institute, Johannesburg.
2005 – 2007: Research Fellow, London School of Hygiene & Tropical Medicine. Based at Aurum Institute, Johannesburg.
2001: Research assistant, National Centre for Epidemiology and Population Health, Australian National University, Canberra.
2000 – 2001: Research assistant, Centre for Socioeconomic Research, Welsh School of Pharmacy, University of Wales, Cardiff.
Committees and reviewing
Member of the Welsh Government's Innovation Advisory Council for Wales
Statistical reviewer for the Lancet journals
Supervisions
I am interested in supervising PhD and Professional Doctorate students in the areas of public health evaluations, epidemiology, quantitative public health, public services innovation and social innovation.
Current supervision
Becky Parish
Research student
Past projects
- Kavi Velen's PhD on "GOOD to GREAT: Strategies to improve the detection of TB amongst household contacts in South Africa"
- Cara O'Connor's PhD on "Mobile Phone Adherence Support for HIV Patients in Manila, Philippines"
- Becky Parish's professional doctorate on "Informed Choice or Informed Voice? A consideration of the impact of proposed NHS service developments on divided communities"
I was a statistical advisor for six PhD students at LSHTM, a role similar to that of co-supervisor.
Contact Details
LewisJ78@cardiff.ac.uk
+44 29208 79874
sbarc|spark, Room 03.14, Maindy Road, Cathays, Cardiff, CF24 4HQ
Glamorgan Building, Room 2.41A, King Edward VII Avenue, Cardiff, CF10 3WA
+44 29208 79874
sbarc|spark, Room 03.14, Maindy Road, Cathays, Cardiff, CF24 4HQ
Glamorgan Building, Room 2.41A, King Edward VII Avenue, Cardiff, CF10 3WA
