![James Lewis](https://profiles-cardiff.imgix.net/attachments/5980?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Professor James Lewis
(he/him)
- Available for postgraduate supervision
Teams and roles for James Lewis
Professor
Overview
I am a professor in the School of Social Sciences and the Centre for the Development, Evaluation, Complexity and Implementation in Public Health Improvement (DECIPHer). I serve on DECIPHer's Executive Management team and I am a co-investigator on our HCRW Sustainability Funding 2025-30 (£2.9m), and lead on our International work. I am also a co-investigator on our Centre for Adult Social Care (HCRW funded, £3m), and the Local Policy and Innovation Partnership for Rural Wales (ESRC funded, £5m). My research is focused on better understanding public health challenges and designing and evaluating relevant interventions.
From March 2018 to September 2023 I was the director of Cardiff University's Y Lab - the Public Services Innovation Lab for Wales. At Y Lab we supported and promoted experimentation and innovation in public services in Wales, and conducted research on the hows and whys of public services innovation. We brought in £12m of funding, including £10m to Cardiff University. We were honoured to win Cardiff University’s Celebrating Excellence Award in the Excellence in Innovation and Enterprise category in 2022.
Prior to this, I worked as a statistician and epidemiologist at the London School of Hygiene & Tropical Medicine for 12 years. I conducted research in global health, focusing on pragmatic evaluations of health system innovations across a range of disease areas and geographies. I lived in Johannesburg for seven years.
Publication
2025
- Donaldson, C. et al. 2025. Associations of perceived school and year group climate with mental health among children aged 7-to-11 years. Child Indicators Research 18 (2), pp.885-904. (10.1007/s12187-024-10213-7)
2024
- Khan, P. Y. et al., 2024. Insights into tuberculosis burden in Karachi, Pakistan: A concurrent adult tuberculosis prevalence and child Mycobacterium tuberculosis infection survey. PLOS Global Public Health 4 (8) e0002155. (10.1371/journal.pgph.0002155)
- O'Connor, C. et al., 2024. Changes in adherence and viral load suppression among people with HIV in Manila: Outcomes of the Philippines Connect for Life Study. AIDS and Behavior 28 (3), pp.837-853. (10.1007/s10461-023-04190-1)
2023
- Irfan, M. et al. 2023. Mapping social capital across Wales (UK) using secondary data and spatial analysis. SN Social Sciences 3 56. (10.1007/s43545-023-00639-1)
- Mutale, W. et al., 2023. Protocol-driven primary care and community linkage to reduce all-cause mortality in rural Zambia: a stepped-wedge cluster randomized trial. Frontiers in Public Health 11 1214066. (10.3389/fpubh.2023.1214066)
2022
- Hardyman, W. et al. 2022. Enhancing public service innovation through value co-creation: capacity building and the 'innovative imagination’. Public Money and Management 42 (5), pp.332-340.
- O'Connor, C. et al., 2022. Delivering an mHealth adherence support intervention for patients with HIV: Mixed methods process evaluation of the Philippines connect for life study. JMIR Formative Research 6 (8) e37163. (10.2196/37163)
- O'Connor, C. et al., 2022. Interactive mobile phone HIV adherence support for men who have sex with men in the Philippines connect for life study: mixed methods approach to intervention development and pilot testing. JMIR Formative Research 6 (2) e30811. (10.2196/30811)
2021
- O’Connor, C. et al., 2021. Risk factors affecting adherence to antiretroviral therapy among HIV patients in Manila, Philippines: a baseline cross-sectional analysis of the Philippines Connect for Life Study. Sexual Health 18 (1), pp.95-103. (10.1071/SH20028)
- Sarrassat, S. et al., 2021. An Integrated eDiagnosis Approach (IeDA) versus standard IMCI for assessing and managing childhood illness in Burkina Faso: a stepped-wedge cluster randomised trial. BMC Health Services Research 21 354. (10.1186/s12913-021-06317-3)
- Velen, K. et al., 2021. Performance of GeneXpert MTB/RIF for diagnosing tuberculosis among symptomatic household contacts of index patients in South Africa. Open Forum Infectious Diseases 8 (4) ofab025. (10.1093/ofid/ofab025)
2020
- Izzo, A. A. et al., 2020. An ecological study to evaluate the association of Bacillus Calmette-Guerin (BCG) vaccination on cases of SARS-CoV2 infection and mortality from COVID-19. PLoS ONE 15 (12) e0243707. (10.1371/journal.pone.0243707)
- Stagg, H. R. et al., 2020. Temporal factors and missed doses of tuberculosis treatment: a causal associations approach to analyses of digital adherence data. Annals of the American Thoracic Society 17 (4), pp.438-449. (10.1513/AnnalsATS.201905-394OC)
2019
- Hargreaves, J. R. et al., 2019. Five challenges in the design and conduct of IS trials for HIV prevention and treatment. Journal of Acquired Immune Deficiency Syndromes 82 , pp.S261-S270. (10.1097/QAI.0000000000002192)
- Hensen, B. et al., 2019. Application of an HIV prevention cascade to identify gaps in increasing coverage of voluntary medical male circumcision services in 42 rural Zambian communities. AIDS and Behavior 23 (5), pp.1095-1103. (10.1007/s10461-019-02407-w)
- Williams, A. et al. 2019. Evaluation of the clinical effectiveness of a work-based mentoring programme to develop clinical reasoning on patient outcome: A stepped wedge cluster randomised controlled trial. PLoS ONE 14 (7) e0220110. (10.1371/journal.pone.0220110)
2018
- Lewis, J. J. et al. 2018. Evaluation of a medication monitor-based treatment strategy for drug-sensitive tuberculosis patients in China: study protocol for a cluster randomised controlled trial. Trials 19 , pp.-. 398. (10.1186/s13063-018-2650-3)
- Page-Shipp, L. et al., 2018. Household point of care CD4 testing and isoniazid preventive therapy initiation in a household TB contact tracing programme in two districts of South Africa. PLoS ONE 13 (3) e0192089. (10.1371/journal.pone.0192089)
2017
- Mastropasqua, R. et al., 2017. Black patients sustain vision loss while White and South Asian patients gain vision following delamination or segmentation surgery for tractional complications associated with proliferative diabetic retinopathy. Eye 31 (10), pp.1468-1474. (10.1038/eye.2017.95)
- Wingfield, T. et al., 2017. A randomized controlled study of socioeconomic support to enhance tuberculosis prevention and treatment, Peru. Bulletin of the World Health Organization 95 , pp.270-280. (10.2471/BLT.16.170167)
- Wingfield, T. et al., 2017. Socioeconomic support to improve initiation of tuberculosis preventive therapy and increase tuberculosis treatment success in Peru: a household-randomised, controlled evaluation. Lancet 389 , pp.16-16.
2016
- Blanchet, K. et al., 2016. A mixed methods protocol to evaluate the effect and cost-effectiveness of an Integrated electronic Diagnosis Approach (IeDA) for the management of childhood illnesses at primary health facilities in Burkina Faso. Implementation Science 11 , pp.-. 111. (10.1186/s13012-016-0476-5)
- Greenland, K. et al., 2016. Multiple behaviour change intervention for diarrhoea control in Lusaka, Zambia: a cluster randomised trial. Lancet Global Health 4 (12), pp.e966-e977. (10.1016/S2214-109X(16)30262-5)
- Hermans, S. M. et al., 2016. The timing of tuberculosis after isoniazid preventive therapy among gold miners in South Africa: a prospective cohort study. BMC Medicine 14 , pp.-. 45. (10.1186/s12916-016-0589-3)
- Jha, S. et al., 2016. Cost-effectiveness of automated digital microscopy for diagnosis of active tuberculosis. PLoS ONE 11 (6), pp.-. e0157554. (10.1371/journal.pone.0157554)
- Kliemann, B. S. et al., 2016. Socioeconomic determinants of antibiotic consumption in the state of Sao Paulo, Brazil: The effect of restricting over-the-counter sales. PLoS ONE 11 (12), pp.-. e0167885. (10.1371/journal.pone.0167885)
- Velen, K. et al., 2016. Household HIV testing uptake among contacts of TB patients in South Africa. PLoS ONE 11 (5), pp.-. e0155688. (10.1371/journal.pone.0155688)
- Wingfield, T. et al., 2016. The economic effects of supporting tuberculosis-affected households in Peru. European Respiratory Journal 48 (5), pp.1396-1410. (10.1183/13993003.00066-2016)
2015
- Beard, E. et al., 2015. Stepped wedge randomised controlled trials: systematic review of studies published between 2010 and 2014. Trials 16 , pp.-. 353. (10.1186/s13063-015-0839-2)
- Copas, A. J. et al., 2015. Designing a stepped wedge trial: three main designs, carry-over effects and randomisation approaches. Trials 16 352. (10.1186/s13063-015-0842-7)
- Davey, C. et al., 2015. Analysis and reporting of stepped wedge randomised controlled trials: synthesis and critical appraisal of published studies, 2010 to 2014. Trials 16 , pp.-. 358. (10.1186/s13063-015-0838-3)
- Hargreaves, J. R. et al., 2015. Five questions to consider before conducting a stepped wedge trial. Trials 16 350. (10.1186/s13063-015-0841-8)
- Hensen, B. et al., 2015. Factors associated with HIV-testing and acceptance of an offer of home-based testing by men in rural Zambia. AIDS and Behavior 19 (3), pp.492-504. (10.1007/s10461-014-0866-0)
- Hensen, B. et al., 2015. Frequency of HIV-testing and factors associated with multiple lifetime HIV-testing among a rural population of Zambian men. BMC Public Health 15 960. (10.1186/s12889-015-2259-3)
- Ismail, N. A. et al., 2015. Performance of a novel algorithm using automated digital microscopy for diagnosing tuberculosis. American Journal of Respiratory and Critical Care Medicine 191 (12), pp.1443-1449. (10.1164/rccm.201502-0390OC)
- Liu, X. et al., 2015. Effectiveness of electronic reminders to improve medication adherence in tuberculosis patients: a cluster-randomised trial. PLoS Medicine 12 (9) e1001876. (10.1371/journal.pmed.1001876)
- Mathema, B. et al., 2015. Molecular epidemiology of Mycobacterium tuberculosis among South African gold miners. Annals of the American Thoracic Society 12 (1), pp.12-20. (10.1513/AnnalsATS.201404-150OC)
- Ononge, S. et al., 2015. Effectiveness and safety of misoprostol distributed to antenatal women to prevent postpartum haemorrhage after child-births: a stepped-wedge cluster-randomized trial. BMC Pregnancy and Childbirth 15 , pp.-. 315. (10.1186/s12884-015-0750-6)
- Prost, A. et al., 2015. Logistic, ethical, and political dimensions of stepped wedge trials: critical review and case studies. Trials 16 , pp.-. 351. (10.1186/s13063-015-0837-4)
- van Halsema, C. L. et al., 2015. Clinical relevance of nontuberculous mycobacteria isolated from sputum in a gold mining workforce in South Africa: an observational, clinical study. BioMed Research International 2015 959107. (10.1155/2015/959107)
- van Halsema, C. L. et al., 2015. The effect of antiretroviral therapy and CD4 count on markers of infectiousness in HIV-associated tuberculosis. Journal of Acquired Immune Deficiency Syndromes 70 (1), pp.104-108. (10.1097/QAI.0000000000000684)
- Vynnycky, E. et al., 2015. Tuberculosis control in South African gold mines: Mathematical modeling of a trial of community-wide isoniazid preventive therapy. American Journal of Epidemiology 181 (8), pp.619-632. (10.1093/aje/kwu320)
- Wingfield, T. et al., 2015. Designing and implementing a socioeconomic intervention to enhance TB control: operational evidence from the CRESIPT project in Peru. BMC Public Health 15 , pp.-. 810. (10.1186/s12889-015-2128-0)
2014
- Churchyard, G. J. et al., 2014. A trial of mass isoniazid preventive therapy for tuberculosis control. New England Journal of Medicine 370 (4), pp.301-310. (10.1056/NEJMoa1214289)
- Ferguson, L. et al., 2014. Linking women who test HIV-positive in pregnancy-related services to HIV care and treatment services in Kenya: a mixed methods prospective cohort study. PLoS ONE 9 (3) e89764. (10.1371/journal.pone.0089764)
- Mutale, W. et al., 2014. Application of balanced scorecard in the evaluation of a complex health system intervention: 12 months post intervention findings from the BHOMA intervention: A cluster randomised trial in Zambia. PLoS ONE 9 (4) e93977. (10.1371/journal.pone.0093977)
- Smith, J. et al., 2014. The distribution of sex acts and condom use within partnerships in a rural sub-Saharan African population. PLoS ONE 9 (2) e88378. (10.1371/journal.pone.0088378)
- Wingfield, T. et al., 2014. The seasonality of tuberculosis, sunlight, vitamin D, and household crowding. The Journal of Infectious Diseases 210 (5), pp.774-783. (10.1093/infdis/jiu121)
2013
- Hensen, B. et al., 2013. Systematic review of strategies to increase men's HIV-testing in sub-Saharan Africa. AIDS 28 (14), pp.2133-2145. (10.1097/QAD.0000000000000395)
- Hoffmann, C. J. et al., 2013. Mortality associated with delays between clinic entry and ART initiation in resource-limited settings. Journal of Acquired Immune Deficiency Syndromes 63 (1), pp.105-111. (10.1097/QAI.0b013e3182893fb4)
- Letang, E. et al., 2013. Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma. AIDS 27 (10), pp.1603-1613. (10.1097/qad.0b013e328360a5a1)
- Lewis, J. J. et al. 2013. Eligibility for isoniazid preventive therapy in South African gold mines. PLoS ONE 8 (11) e81376. (10.1371/journal.pone.0081376)
- Marais, E. et al., 2013. Treatment outcomes of multidrug-resistant tuberculosis patients in Gauteng, South Africa. Infection 42 (2), pp.405-413. (10.1007/s15010-013-0572-2)
- Velen, K. et al., 2013. Comparison of Tenofovir, Zidovudine, or Stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study. PLoS ONE 8 (5) e64459. (10.1371/journal.pone.0064459)
2012
- Dorman, S. E. et al., 2012. Genotype MTBDR plus for direct detection of mycobacterium tuberculosis and drug resistance in strains from gold miners in South Africa. Journal of Clinical Microbiology 50 (4), pp.1189-1194. (10.1128/JCM.05723-11)
- Dorman, S. E. et al., 2012. Performance characteristics of the Cepheid Xpert MTB/RIF test in a tuberculosis prevalence survey. PLoS ONE 7 (8) e43307. (10.1371/journal.pone.0043307)
- Ferguson, L. et al., 2012. Patient attrition between diagnosis with HIV in pregnancy-related services and long-term HIV care and treatment services in Kenya. Journal of Acquired Immune Deficiency Syndrome 60 (3), pp.e90-e97. (10.1097/QAI.0b013e318253258a)
- Lewis, J. J. et al. 2012. "Proof-of-concept" Evaluation of an automated sputum smear microscopy system for tuberculosis diagnosis. PLoS ONE 7 (11)(10.1371/journal.pone.0050173)
- van Halsema, C. L. et al., 2012. Trends in drug-resistant tuberculosis in a gold-mining workforce in South Africa, 2002-2008. International Journal of Tuberculosis and Lung Disease 16 (7), pp.967-973. (10.5588/ijtld.11.0122)
2011
- Kranzer, K. et al., 2011. Antiretroviral treatment cohort analysis using time-updated CD4 counts: assessment of bias with different analytic methods. PLoS ONE 6 (11) e27763. (10.1371/journal.pone.0027763)
2010
- Churchyard, G. J. et al., 2010. Symptom and chest radiographic screening for infectious tuberculosis prior to starting isoniazid preventive therapy: yield and proportion missed at screening. AIDS 24 (Suppl), pp.S19-S27. (10.1097/01.aids.0000391018.72542.46)
- Grant, A. D. et al., 2010. 'Team up against TB': promoting involvement in Thibela TB, a trial of community-wide tuberculosis preventive therapy. AIDS 24 (Suppl), pp.s37-s44. (10.1097/01.aids.0000391020.10661.eb)
- Kranzer, K. et al., 2010. Treatment interruption in a primary care antiretroviral therapy program in South Africa: cohort analysis of trends and risk factors. Journal of Acquired Immune Deficiency Syndrome 55 (3), pp.e17-e23. (10.1097/QAI.0b013e3181f275fd)
- Lawn, S. D. et al., 2010. Antiretrovirals and isoniazid preventive therapy in the prevention of HIV-associated tuberculosis in settings with limited health-care resources. The Lancet Infectious Diseases 10 (7), pp.489-498. (10.1016/S1473-3099(10)70078-5)
- van Halsema, C. L. et al., 2010. Tuberculosis outcomes and drug susceptibility in individuals exposed to isoniazid preventive therapy in a high HIV prevalence setting. AIDS 24 (7), pp.1051-1055. (10.1097/QAD.0b013e32833849df)
2009
- Hanifer, Y. et al., 2009. Prevalence of latent tuberculosis infection among gold miners in South Africa. International Journal of Tuberculosis and Lung Disease 13 (1), pp.39-46.
- Lewis, J. J. et al. 2009. HIV infection does not affect active case finding of tuberculosis in South African gold miners. American Journal of Respiratory and Critical Care Medicine 180 (12), pp.1165-1281. (10.1164/rccm.200806-846OC)
2007
- Hallett, T. B. et al., 2007. Behaviour change in generalised HIV epidemics: impact of reducing cross-generational sex and delaying age at sexual debut. Sexually Transmitted Infections 83 (suppl), pp.i50-i54. (10.1136/sti.2006.023606)
- Hallett, T. B. et al., 2007. Age at first sex and HIV infection in rural Zimbabwe. Studies in Family Planning 38 (1), pp.1-10. (10.1111/j.1728-4465.2007.00111.x)
- Hanifa, Y. et al., 2007. Evaluation of the Arkansas method of urine testing for isoniazid in South Africa. International Journal of Tuberculosis and Lung Disease 11 (11), pp.1232-1236.
- Lewis, J. J. C. et al. 2007. Evaluating the proximate determinants framework for HIV infection in rural Zimbabwe. Sexually Transmitted Infections 83 (suppl), pp.i61-i69. (10.1136/sti.2006.023671)
- Lopman, B. et al., 2007. HIV incidence and poverty in Manicaland, Zimbabwe: is HIV becoming a disease of the poor?. AIDS 21 (Suppl), pp.S57-S66. (10.1097/01.aids.0000300536.82354.52)
2006
- Gregson, S. et al., 2006. HIV decline associated with behavior change in Eastern Zimbabwe. Science 311 (5761), pp.664-666. (10.1126/science.1121054)
2005
- Lewis, J. J. C. et al. 2005. Patterns of uptake of treatment for self reported sexually transmitted infection symptoms in rural Zimbabwe. Sexually Transmitted Infections 81 (4), pp.326-332. (10.1136/sti.2004.012773)
- Lewis, J. J. et al. 2005. Beer halls as a focus for HIV prevention activities in rural Zimbabwe. Sexually Transmitted Diseases 32 (6), pp.364-369. (10.1097/01.olq.0000154506.84492.61)
2004
- Grassly, N. et al., 2004. Comparison of household-survey estimates with projections of mortality and orphan numbers in sub-Saharan Africa in the era of HIV/AIDS. Population Studies 58 (2), pp.207-217. (10.1080/0032472042000224431)
- Lewis, J. J. et al. 2004. The population impact of HIV on fertility in sub-Saharan Africa. AIDS 18 (Supp), pp.S35-S43. (10.1097/00002030-200406002-00005)
- Salek, M. et al. 2004. Quality of life improvement in treatment of psoriasis with intermittent short course Cyclosporin (Neoral®). Quality of Life Research 13 (1), pp.91-95. (10.1023/B:QURE.0000015293.69661.ff)
2003
- Becker, N. G. et al., 2003. Age-specific back-projection of HIV diagnosis data. Statistics in Medicine 22 (13), pp.2177-2190. (10.1002/sim.1406)
1995
- Gregson, S. et al., 1995. HIV infection and reproductive health in teenage women orphaned and made vulnerable by AIDS in Zimbabwe. AIDS Care 17 (7), pp.785-794. (10.1080/09540120500258029)
Articles
- Beard, E. et al., 2015. Stepped wedge randomised controlled trials: systematic review of studies published between 2010 and 2014. Trials 16 , pp.-. 353. (10.1186/s13063-015-0839-2)
- Becker, N. G. et al., 2003. Age-specific back-projection of HIV diagnosis data. Statistics in Medicine 22 (13), pp.2177-2190. (10.1002/sim.1406)
- Blanchet, K. et al., 2016. A mixed methods protocol to evaluate the effect and cost-effectiveness of an Integrated electronic Diagnosis Approach (IeDA) for the management of childhood illnesses at primary health facilities in Burkina Faso. Implementation Science 11 , pp.-. 111. (10.1186/s13012-016-0476-5)
- Churchyard, G. J. et al., 2014. A trial of mass isoniazid preventive therapy for tuberculosis control. New England Journal of Medicine 370 (4), pp.301-310. (10.1056/NEJMoa1214289)
- Churchyard, G. J. et al., 2010. Symptom and chest radiographic screening for infectious tuberculosis prior to starting isoniazid preventive therapy: yield and proportion missed at screening. AIDS 24 (Suppl), pp.S19-S27. (10.1097/01.aids.0000391018.72542.46)
- Copas, A. J. et al., 2015. Designing a stepped wedge trial: three main designs, carry-over effects and randomisation approaches. Trials 16 352. (10.1186/s13063-015-0842-7)
- Davey, C. et al., 2015. Analysis and reporting of stepped wedge randomised controlled trials: synthesis and critical appraisal of published studies, 2010 to 2014. Trials 16 , pp.-. 358. (10.1186/s13063-015-0838-3)
- Donaldson, C. et al. 2025. Associations of perceived school and year group climate with mental health among children aged 7-to-11 years. Child Indicators Research 18 (2), pp.885-904. (10.1007/s12187-024-10213-7)
- Dorman, S. E. et al., 2012. Genotype MTBDR plus for direct detection of mycobacterium tuberculosis and drug resistance in strains from gold miners in South Africa. Journal of Clinical Microbiology 50 (4), pp.1189-1194. (10.1128/JCM.05723-11)
- Dorman, S. E. et al., 2012. Performance characteristics of the Cepheid Xpert MTB/RIF test in a tuberculosis prevalence survey. PLoS ONE 7 (8) e43307. (10.1371/journal.pone.0043307)
- Ferguson, L. et al., 2014. Linking women who test HIV-positive in pregnancy-related services to HIV care and treatment services in Kenya: a mixed methods prospective cohort study. PLoS ONE 9 (3) e89764. (10.1371/journal.pone.0089764)
- Ferguson, L. et al., 2012. Patient attrition between diagnosis with HIV in pregnancy-related services and long-term HIV care and treatment services in Kenya. Journal of Acquired Immune Deficiency Syndrome 60 (3), pp.e90-e97. (10.1097/QAI.0b013e318253258a)
- Grant, A. D. et al., 2010. 'Team up against TB': promoting involvement in Thibela TB, a trial of community-wide tuberculosis preventive therapy. AIDS 24 (Suppl), pp.s37-s44. (10.1097/01.aids.0000391020.10661.eb)
- Grassly, N. et al., 2004. Comparison of household-survey estimates with projections of mortality and orphan numbers in sub-Saharan Africa in the era of HIV/AIDS. Population Studies 58 (2), pp.207-217. (10.1080/0032472042000224431)
- Greenland, K. et al., 2016. Multiple behaviour change intervention for diarrhoea control in Lusaka, Zambia: a cluster randomised trial. Lancet Global Health 4 (12), pp.e966-e977. (10.1016/S2214-109X(16)30262-5)
- Gregson, S. et al., 1995. HIV infection and reproductive health in teenage women orphaned and made vulnerable by AIDS in Zimbabwe. AIDS Care 17 (7), pp.785-794. (10.1080/09540120500258029)
- Gregson, S. et al., 2006. HIV decline associated with behavior change in Eastern Zimbabwe. Science 311 (5761), pp.664-666. (10.1126/science.1121054)
- Hallett, T. B. et al., 2007. Behaviour change in generalised HIV epidemics: impact of reducing cross-generational sex and delaying age at sexual debut. Sexually Transmitted Infections 83 (suppl), pp.i50-i54. (10.1136/sti.2006.023606)
- Hallett, T. B. et al., 2007. Age at first sex and HIV infection in rural Zimbabwe. Studies in Family Planning 38 (1), pp.1-10. (10.1111/j.1728-4465.2007.00111.x)
- Hanifa, Y. et al., 2007. Evaluation of the Arkansas method of urine testing for isoniazid in South Africa. International Journal of Tuberculosis and Lung Disease 11 (11), pp.1232-1236.
- Hanifer, Y. et al., 2009. Prevalence of latent tuberculosis infection among gold miners in South Africa. International Journal of Tuberculosis and Lung Disease 13 (1), pp.39-46.
- Hardyman, W. et al. 2022. Enhancing public service innovation through value co-creation: capacity building and the 'innovative imagination’. Public Money and Management 42 (5), pp.332-340.
- Hargreaves, J. R. et al., 2015. Five questions to consider before conducting a stepped wedge trial. Trials 16 350. (10.1186/s13063-015-0841-8)
- Hargreaves, J. R. et al., 2019. Five challenges in the design and conduct of IS trials for HIV prevention and treatment. Journal of Acquired Immune Deficiency Syndromes 82 , pp.S261-S270. (10.1097/QAI.0000000000002192)
- Hensen, B. et al., 2015. Factors associated with HIV-testing and acceptance of an offer of home-based testing by men in rural Zambia. AIDS and Behavior 19 (3), pp.492-504. (10.1007/s10461-014-0866-0)
- Hensen, B. et al., 2015. Frequency of HIV-testing and factors associated with multiple lifetime HIV-testing among a rural population of Zambian men. BMC Public Health 15 960. (10.1186/s12889-015-2259-3)
- Hensen, B. et al., 2019. Application of an HIV prevention cascade to identify gaps in increasing coverage of voluntary medical male circumcision services in 42 rural Zambian communities. AIDS and Behavior 23 (5), pp.1095-1103. (10.1007/s10461-019-02407-w)
- Hensen, B. et al., 2013. Systematic review of strategies to increase men's HIV-testing in sub-Saharan Africa. AIDS 28 (14), pp.2133-2145. (10.1097/QAD.0000000000000395)
- Hermans, S. M. et al., 2016. The timing of tuberculosis after isoniazid preventive therapy among gold miners in South Africa: a prospective cohort study. BMC Medicine 14 , pp.-. 45. (10.1186/s12916-016-0589-3)
- Hoffmann, C. J. et al., 2013. Mortality associated with delays between clinic entry and ART initiation in resource-limited settings. Journal of Acquired Immune Deficiency Syndromes 63 (1), pp.105-111. (10.1097/QAI.0b013e3182893fb4)
- Irfan, M. et al. 2023. Mapping social capital across Wales (UK) using secondary data and spatial analysis. SN Social Sciences 3 56. (10.1007/s43545-023-00639-1)
- Ismail, N. A. et al., 2015. Performance of a novel algorithm using automated digital microscopy for diagnosing tuberculosis. American Journal of Respiratory and Critical Care Medicine 191 (12), pp.1443-1449. (10.1164/rccm.201502-0390OC)
- Izzo, A. A. et al., 2020. An ecological study to evaluate the association of Bacillus Calmette-Guerin (BCG) vaccination on cases of SARS-CoV2 infection and mortality from COVID-19. PLoS ONE 15 (12) e0243707. (10.1371/journal.pone.0243707)
- Jha, S. et al., 2016. Cost-effectiveness of automated digital microscopy for diagnosis of active tuberculosis. PLoS ONE 11 (6), pp.-. e0157554. (10.1371/journal.pone.0157554)
- Khan, P. Y. et al., 2024. Insights into tuberculosis burden in Karachi, Pakistan: A concurrent adult tuberculosis prevalence and child Mycobacterium tuberculosis infection survey. PLOS Global Public Health 4 (8) e0002155. (10.1371/journal.pgph.0002155)
- Kliemann, B. S. et al., 2016. Socioeconomic determinants of antibiotic consumption in the state of Sao Paulo, Brazil: The effect of restricting over-the-counter sales. PLoS ONE 11 (12), pp.-. e0167885. (10.1371/journal.pone.0167885)
- Kranzer, K. et al., 2010. Treatment interruption in a primary care antiretroviral therapy program in South Africa: cohort analysis of trends and risk factors. Journal of Acquired Immune Deficiency Syndrome 55 (3), pp.e17-e23. (10.1097/QAI.0b013e3181f275fd)
- Kranzer, K. et al., 2011. Antiretroviral treatment cohort analysis using time-updated CD4 counts: assessment of bias with different analytic methods. PLoS ONE 6 (11) e27763. (10.1371/journal.pone.0027763)
- Lawn, S. D. et al., 2010. Antiretrovirals and isoniazid preventive therapy in the prevention of HIV-associated tuberculosis in settings with limited health-care resources. The Lancet Infectious Diseases 10 (7), pp.489-498. (10.1016/S1473-3099(10)70078-5)
- Letang, E. et al., 2013. Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma. AIDS 27 (10), pp.1603-1613. (10.1097/qad.0b013e328360a5a1)
- Lewis, J. J. C. et al. 2007. Evaluating the proximate determinants framework for HIV infection in rural Zimbabwe. Sexually Transmitted Infections 83 (suppl), pp.i61-i69. (10.1136/sti.2006.023671)
- Lewis, J. J. C. et al. 2005. Patterns of uptake of treatment for self reported sexually transmitted infection symptoms in rural Zimbabwe. Sexually Transmitted Infections 81 (4), pp.326-332. (10.1136/sti.2004.012773)
- Lewis, J. J. et al. 2009. HIV infection does not affect active case finding of tuberculosis in South African gold miners. American Journal of Respiratory and Critical Care Medicine 180 (12), pp.1165-1281. (10.1164/rccm.200806-846OC)
- Lewis, J. J. et al. 2012. "Proof-of-concept" Evaluation of an automated sputum smear microscopy system for tuberculosis diagnosis. PLoS ONE 7 (11)(10.1371/journal.pone.0050173)
- Lewis, J. J. et al. 2013. Eligibility for isoniazid preventive therapy in South African gold mines. PLoS ONE 8 (11) e81376. (10.1371/journal.pone.0081376)
- Lewis, J. J. et al. 2018. Evaluation of a medication monitor-based treatment strategy for drug-sensitive tuberculosis patients in China: study protocol for a cluster randomised controlled trial. Trials 19 , pp.-. 398. (10.1186/s13063-018-2650-3)
- Lewis, J. J. et al. 2005. Beer halls as a focus for HIV prevention activities in rural Zimbabwe. Sexually Transmitted Diseases 32 (6), pp.364-369. (10.1097/01.olq.0000154506.84492.61)
- Lewis, J. J. et al. 2004. The population impact of HIV on fertility in sub-Saharan Africa. AIDS 18 (Supp), pp.S35-S43. (10.1097/00002030-200406002-00005)
- Liu, X. et al., 2015. Effectiveness of electronic reminders to improve medication adherence in tuberculosis patients: a cluster-randomised trial. PLoS Medicine 12 (9) e1001876. (10.1371/journal.pmed.1001876)
- Lopman, B. et al., 2007. HIV incidence and poverty in Manicaland, Zimbabwe: is HIV becoming a disease of the poor?. AIDS 21 (Suppl), pp.S57-S66. (10.1097/01.aids.0000300536.82354.52)
- Marais, E. et al., 2013. Treatment outcomes of multidrug-resistant tuberculosis patients in Gauteng, South Africa. Infection 42 (2), pp.405-413. (10.1007/s15010-013-0572-2)
- Mastropasqua, R. et al., 2017. Black patients sustain vision loss while White and South Asian patients gain vision following delamination or segmentation surgery for tractional complications associated with proliferative diabetic retinopathy. Eye 31 (10), pp.1468-1474. (10.1038/eye.2017.95)
- Mathema, B. et al., 2015. Molecular epidemiology of Mycobacterium tuberculosis among South African gold miners. Annals of the American Thoracic Society 12 (1), pp.12-20. (10.1513/AnnalsATS.201404-150OC)
- Mutale, W. et al., 2023. Protocol-driven primary care and community linkage to reduce all-cause mortality in rural Zambia: a stepped-wedge cluster randomized trial. Frontiers in Public Health 11 1214066. (10.3389/fpubh.2023.1214066)
- Mutale, W. et al., 2014. Application of balanced scorecard in the evaluation of a complex health system intervention: 12 months post intervention findings from the BHOMA intervention: A cluster randomised trial in Zambia. PLoS ONE 9 (4) e93977. (10.1371/journal.pone.0093977)
- O’Connor, C. et al., 2021. Risk factors affecting adherence to antiretroviral therapy among HIV patients in Manila, Philippines: a baseline cross-sectional analysis of the Philippines Connect for Life Study. Sexual Health 18 (1), pp.95-103. (10.1071/SH20028)
- O'Connor, C. et al., 2024. Changes in adherence and viral load suppression among people with HIV in Manila: Outcomes of the Philippines Connect for Life Study. AIDS and Behavior 28 (3), pp.837-853. (10.1007/s10461-023-04190-1)
- O'Connor, C. et al., 2022. Delivering an mHealth adherence support intervention for patients with HIV: Mixed methods process evaluation of the Philippines connect for life study. JMIR Formative Research 6 (8) e37163. (10.2196/37163)
- O'Connor, C. et al., 2022. Interactive mobile phone HIV adherence support for men who have sex with men in the Philippines connect for life study: mixed methods approach to intervention development and pilot testing. JMIR Formative Research 6 (2) e30811. (10.2196/30811)
- Ononge, S. et al., 2015. Effectiveness and safety of misoprostol distributed to antenatal women to prevent postpartum haemorrhage after child-births: a stepped-wedge cluster-randomized trial. BMC Pregnancy and Childbirth 15 , pp.-. 315. (10.1186/s12884-015-0750-6)
- Page-Shipp, L. et al., 2018. Household point of care CD4 testing and isoniazid preventive therapy initiation in a household TB contact tracing programme in two districts of South Africa. PLoS ONE 13 (3) e0192089. (10.1371/journal.pone.0192089)
- Prost, A. et al., 2015. Logistic, ethical, and political dimensions of stepped wedge trials: critical review and case studies. Trials 16 , pp.-. 351. (10.1186/s13063-015-0837-4)
- Salek, M. et al. 2004. Quality of life improvement in treatment of psoriasis with intermittent short course Cyclosporin (Neoral®). Quality of Life Research 13 (1), pp.91-95. (10.1023/B:QURE.0000015293.69661.ff)
- Sarrassat, S. et al., 2021. An Integrated eDiagnosis Approach (IeDA) versus standard IMCI for assessing and managing childhood illness in Burkina Faso: a stepped-wedge cluster randomised trial. BMC Health Services Research 21 354. (10.1186/s12913-021-06317-3)
- Smith, J. et al., 2014. The distribution of sex acts and condom use within partnerships in a rural sub-Saharan African population. PLoS ONE 9 (2) e88378. (10.1371/journal.pone.0088378)
- Stagg, H. R. et al., 2020. Temporal factors and missed doses of tuberculosis treatment: a causal associations approach to analyses of digital adherence data. Annals of the American Thoracic Society 17 (4), pp.438-449. (10.1513/AnnalsATS.201905-394OC)
- van Halsema, C. L. et al., 2012. Trends in drug-resistant tuberculosis in a gold-mining workforce in South Africa, 2002-2008. International Journal of Tuberculosis and Lung Disease 16 (7), pp.967-973. (10.5588/ijtld.11.0122)
- van Halsema, C. L. et al., 2015. Clinical relevance of nontuberculous mycobacteria isolated from sputum in a gold mining workforce in South Africa: an observational, clinical study. BioMed Research International 2015 959107. (10.1155/2015/959107)
- van Halsema, C. L. et al., 2015. The effect of antiretroviral therapy and CD4 count on markers of infectiousness in HIV-associated tuberculosis. Journal of Acquired Immune Deficiency Syndromes 70 (1), pp.104-108. (10.1097/QAI.0000000000000684)
- van Halsema, C. L. et al., 2010. Tuberculosis outcomes and drug susceptibility in individuals exposed to isoniazid preventive therapy in a high HIV prevalence setting. AIDS 24 (7), pp.1051-1055. (10.1097/QAD.0b013e32833849df)
- Velen, K. et al., 2013. Comparison of Tenofovir, Zidovudine, or Stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study. PLoS ONE 8 (5) e64459. (10.1371/journal.pone.0064459)
- Velen, K. et al., 2016. Household HIV testing uptake among contacts of TB patients in South Africa. PLoS ONE 11 (5), pp.-. e0155688. (10.1371/journal.pone.0155688)
- Velen, K. et al., 2021. Performance of GeneXpert MTB/RIF for diagnosing tuberculosis among symptomatic household contacts of index patients in South Africa. Open Forum Infectious Diseases 8 (4) ofab025. (10.1093/ofid/ofab025)
- Vynnycky, E. et al., 2015. Tuberculosis control in South African gold mines: Mathematical modeling of a trial of community-wide isoniazid preventive therapy. American Journal of Epidemiology 181 (8), pp.619-632. (10.1093/aje/kwu320)
- Williams, A. et al. 2019. Evaluation of the clinical effectiveness of a work-based mentoring programme to develop clinical reasoning on patient outcome: A stepped wedge cluster randomised controlled trial. PLoS ONE 14 (7) e0220110. (10.1371/journal.pone.0220110)
- Wingfield, T. et al., 2014. The seasonality of tuberculosis, sunlight, vitamin D, and household crowding. The Journal of Infectious Diseases 210 (5), pp.774-783. (10.1093/infdis/jiu121)
- Wingfield, T. et al., 2015. Designing and implementing a socioeconomic intervention to enhance TB control: operational evidence from the CRESIPT project in Peru. BMC Public Health 15 , pp.-. 810. (10.1186/s12889-015-2128-0)
- Wingfield, T. et al., 2017. A randomized controlled study of socioeconomic support to enhance tuberculosis prevention and treatment, Peru. Bulletin of the World Health Organization 95 , pp.270-280. (10.2471/BLT.16.170167)
- Wingfield, T. et al., 2017. Socioeconomic support to improve initiation of tuberculosis preventive therapy and increase tuberculosis treatment success in Peru: a household-randomised, controlled evaluation. Lancet 389 , pp.16-16.
- Wingfield, T. et al., 2016. The economic effects of supporting tuberculosis-affected households in Peru. European Respiratory Journal 48 (5), pp.1396-1410. (10.1183/13993003.00066-2016)
Research
I have been an investigator on grants worth £29m, including £6.5m as principal investigator and £3.7m for international research.
Grant funding
2025-30, DECIPHer Sustainability Infrastructure Funding, £2.9m, HCRW
2024-26, Cymru Wledig LPIP Rural Wales - the Local Policy and Innovation Partnership for Rural Wales, £5m, ESRC
2024-29, Centre for Adult social care REsearch (CARE), £3m, HCRW
2020-24, Cardiff Capital Region Challenge Fund, £1.2m, Cardiff Capital Region City Deal
2020-23, Infuse: Innovative Future Services in the Cardiff Capital Region, £5.6m, Welsh European Funding Office
2021-22, Keeping Wales Safe: COVID behaviours, £300k, Welsh Government
2022, Understanding user needs for support for innovation in social care in Wales, £10k, Social Care Wales
2022, Being Black in Academia: Curation of a Black History Month events series that builds on an ESRC-funded PhD into Black Faculty Experience within Higher Education, £3k, ESRC-AHRC IAA
2019-21, Health,Arts,Research,People (HARP): innovation sprints to increase use of arts for wellbeing in Wales, £650k, Arts Council of Wales
2019-20, Impact of gender on the innovation funding process, £12k, Nesta
2019-20, Co-producing sustainable development through Rule of Law: a Lesotho case-study, £20k, ESRC IAA
2017-20, Innovate to Save: supporting public service teams to improve services & generate cashable savings, £6.5m, Welsh Government
2017-19, iSaathiya: Evaluating Peer Educator Component of India's National Adolescent Health Programme, £660k, MRC and DfID
2016-18, Cluster randomised trial of medication monitors for tuberculosis medication adherence in China, US$629k, Bill and Melinda Gates Foundation
2013-17, Adherence to, and diagnostic outcomes, from e-assessment tool for child health in Burkina Faso, US$670k, Bill and Melinda Gates Foundation
2013-15, INHIBIT-TB: Assessment of household TB preventive therapy and CD4 testing in South Africa, £60k, Sanofi-Aventis
2012-18, Community Randomised Evaluation of Socioeconomic Intervention to Prevent Tuberculosis in Lima, Peru, £1.9m, Joint Global Health Trials consortium and the World Bank
Teaching
Management
I am the teaching team lead for our Social Policy programme
Current Teaching
Knowing the Social World: Online and Offline Surveys (Year 2, Module Convenor)
Evaluating Social Policy, Practice and Innovation (Year 2, Module Convenor)
Quantitative Research Methods (MSc, Module Convenor)
Evaluation: Developing and Evaluating Interventions in Complex Social Systems (Professional Doctorate, Module Convenor)
Undergraduate and postgraduate dissertation supervisor
Recent teaching
Lies, Damned Lies, and Statistics (Year 1, Module Convener 2023-4)
Evaluation: Developing and Evaluating Interventions in Complex Social Systems (MSc, Teaching 2023-4)
Biography
Education
2001 –2005: PhD in Epidemiology at Imperial College London. “Behavioural, demographic and social risk factors for HIV infection in rural Zimbabwe.” Received MRC funding.
1999 –2000: MSc in Applied Statistics at the University of Oxford. Grade: Distinction. Gutierrez Toscano prize for joint top result. Received EPSRC funding.
1996 – 1999: BA (Hons) in Mathematics at the University of Cambridge. Class: 2:1.
Honours and awards
2022 - won Cardiff University’s Celebrating Excellence Award in the Excellence in Innovation and Enterprise category
Professional memberships
Fellow of the Royal Geographical Society
Academic positions
2016 – 2018: Associate Professor, London School of Hygiene & Tropical Medicine. Based in London.
2013 – 2018: Deputy Director, Centre for Evaluation, London School of Hygiene & Tropical Medicine.
2013 – 2016: Senior Lecturer, London School of Hygiene & Tropical Medicine. Based in London.
2012 – 2013: Lecturer, London School of Hygiene & Tropical Medicine. Based in London.
2007 – 2012: Lecturer, London School of Hygiene & Tropical Medicine. Based at Aurum Institute, Johannesburg.
2005 – 2007: Research Fellow, London School of Hygiene & Tropical Medicine. Based at Aurum Institute, Johannesburg.
2001: Research assistant, National Centre for Epidemiology and Population Health, Australian National University, Canberra.
2000 – 2001: Research assistant, Centre for Socioeconomic Research, Welsh School of Pharmacy, University of Wales, Cardiff.
Committees and reviewing
Current work
Committee member reviewing grants for the NIHR Programme Grants for Applied Research scheme
Committee member conducting interviews for the Wellcome Trust Career Development Award scheme
Member of the School Board for the School of Social Sciences
Chair of the Health & Wellbeing Steering Group for the Wales Innovation Network
Member of the Welsh Government's Innovation Advisory Council for Wales
Statistical reviewer for the Lancet journals
Member of two Trial Steering Committees - one for Johns Hopkins University and one for Exeter University
Recent work
Chaired two grant interview panels and one bid review panel for the ESRC in 2022-3
Grant reviewer and/or panel member for the NIHR, ESRC, Wellcome Trust, MRC, UKRI and the EDCTP
I have been the statistical member on four completed Trial Steering Committees - three for Johns Hopkins University and one for Oxford University
Supervisions
I am interested in supervising PhD and Professional Doctorate students in the areas of public health evaluations, epidemiology, quantitative public health, public services innovation and social innovation.
Current supervision
Past projects
- Kavi Velen's PhD on "GOOD to GREAT: Strategies to improve the detection of TB amongst household contacts in South Africa"
- Cara O'Connor's PhD on "Mobile Phone Adherence Support for HIV Patients in Manila, Philippines"
- Becky Parish's professional doctorate on "Informed Choice or Informed Voice? A consideration of the impact of proposed NHS service developments on divided communities"
I was a statistical advisor for six PhD students at LSHTM, a role similar to that of co-supervisor.
Contact Details
[email protected]
+44 29208 79874
sbarc|spark, Room 03.14, Maindy Road, Cathays, Cardiff, CF24 4HQ
Glamorgan Building, Room 2.41A, King Edward VII Avenue, Cardiff, CF10 3WA
+44 29208 79874
sbarc|spark, Room 03.14, Maindy Road, Cathays, Cardiff, CF24 4HQ
Glamorgan Building, Room 2.41A, King Edward VII Avenue, Cardiff, CF10 3WA
