Dr Arthur Morris
Research Associate (Computational Biologist)
School of Biosciences
- MorrisA28@cardiff.ac.uk
- Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX
Overview
My research covers a wide sweep of bioinformatics and genomics pertaining to pathogens of medical significance. My current work includes:
- User acceptance and module testing for the Scalable Pathogen Pipeline Platform (SP3).
- Development of a novel, clincally validated genomics pipelines for facilitating the analysis of pathogen genomes in clinical labs.
- Bioinformatic analysis of environmentally collected waste water.
- Comparative and evolutionary genomics of Welsh SARS-CoV2 genomes.
My primary focus is in attempting to leverage computational algorithms to facilitate the analysis of pathogen genomes, and working closely with teams within Public Health Wales to allow for seamless integration of novel methodologies and software into clinical use.
Publication
2023
- Cotton, S. et al. 2023. Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes. Journal of Hospital Infection 135, pp. 28-36. (10.1016/j.jhin.2023.02.010)
2022
- Willett, B. J. et al. 2022. SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. Nature Microbiology 7, pp. 1161-1179. (10.1038/s41564-022-01143-7)
- Eales, O. et al. 2022. SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2. BMC Infectious Diseases 22(1), article number: 647. (10.1186/s12879-022-07628-4)
- Nickbakhsh, S. et al. 2022. Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning. Scientific Reports 12(1), article number: 11735. (10.1038/s41598-022-15661-1)
- Kläser, K. et al. 2022. COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study. Scientific Reports 12(1), article number: 10904. (10.1038/s41598-022-14016-0)
2021
- Vöhringer, H. S. et al. 2021. Genomic reconstruction of the SARS-CoV-2 epidemic in England. Nature 600(7889), pp. 506-511. (10.1038/s41586-021-04069-y)
2020
- Morris, A., Pachebat, J., Tyson, G., Robinson, G., Chalmers, R. and Swain, M. 2020. Generating reliable genome assemblies of intestinal protozoans from clinical samples for the purpose of biomarker discovery. Presented at: Biomedical Engineering Systems and Technologies BIOSTEC 2019, Prague, Czech Republic, 22-24 February 2019 Presented at Roque, A. et al. eds.Communications in Computer and Information Science, Vol. 1211. Springer, Cham pp. 216-241., (10.1007/978-3-030-46970-2_11)
2019
- Morris, A., Robinson, G., Swain, M. T. and Chalmers, R. M. 2019. Direct sequencing of Cryptosporidium in stool samples for public health. Frontiers in Public Health 7 (10.3389/fpubh.2019.00360)
- Swain, M., Chalmers, R., Robinson, G., Pachebat, J. and Morris, A. 2019. Identifying and resolving genome misassembly issues important for biomarker discovery in the protozoan parasite, cryptosporidium. Presented at: 12th International Joint Conference on Biomedical Engineering Systems and Technologies, Prague, Czech Republic, 22–24 February 2019Proceedings of the 12th International Joint Conference on Biomedical Engineering Systems and Technologies, Vol. 3. pp. 90-100., (10.5220/0007397200900100)
2017
- Castro, P. D. J. and Morris, A. V. 2017. Burrowing mites in companion animals. UK-VET Companion animal 22(8), pp. 446-452. (10.12968/coan.2017.22.8.446)
2016
- Castro, P. D. J. and Morris, A. V. 2016. Feline lungworm: biology, epidemiology, diagnosis and treatment. The Veterinary Nurse 7(9), pp. 508-513. (10.12968/vetn.2016.7.9.508)
Articles
- Cotton, S. et al. 2023. Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes. Journal of Hospital Infection 135, pp. 28-36. (10.1016/j.jhin.2023.02.010)
- Willett, B. J. et al. 2022. SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. Nature Microbiology 7, pp. 1161-1179. (10.1038/s41564-022-01143-7)
- Eales, O. et al. 2022. SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2. BMC Infectious Diseases 22(1), article number: 647. (10.1186/s12879-022-07628-4)
- Nickbakhsh, S. et al. 2022. Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning. Scientific Reports 12(1), article number: 11735. (10.1038/s41598-022-15661-1)
- Kläser, K. et al. 2022. COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study. Scientific Reports 12(1), article number: 10904. (10.1038/s41598-022-14016-0)
- Vöhringer, H. S. et al. 2021. Genomic reconstruction of the SARS-CoV-2 epidemic in England. Nature 600(7889), pp. 506-511. (10.1038/s41586-021-04069-y)
- Morris, A., Robinson, G., Swain, M. T. and Chalmers, R. M. 2019. Direct sequencing of Cryptosporidium in stool samples for public health. Frontiers in Public Health 7 (10.3389/fpubh.2019.00360)
- Castro, P. D. J. and Morris, A. V. 2017. Burrowing mites in companion animals. UK-VET Companion animal 22(8), pp. 446-452. (10.12968/coan.2017.22.8.446)
- Castro, P. D. J. and Morris, A. V. 2016. Feline lungworm: biology, epidemiology, diagnosis and treatment. The Veterinary Nurse 7(9), pp. 508-513. (10.12968/vetn.2016.7.9.508)
Conferences
- Morris, A., Pachebat, J., Tyson, G., Robinson, G., Chalmers, R. and Swain, M. 2020. Generating reliable genome assemblies of intestinal protozoans from clinical samples for the purpose of biomarker discovery. Presented at: Biomedical Engineering Systems and Technologies BIOSTEC 2019, Prague, Czech Republic, 22-24 February 2019 Presented at Roque, A. et al. eds.Communications in Computer and Information Science, Vol. 1211. Springer, Cham pp. 216-241., (10.1007/978-3-030-46970-2_11)
- Swain, M., Chalmers, R., Robinson, G., Pachebat, J. and Morris, A. 2019. Identifying and resolving genome misassembly issues important for biomarker discovery in the protozoan parasite, cryptosporidium. Presented at: 12th International Joint Conference on Biomedical Engineering Systems and Technologies, Prague, Czech Republic, 22–24 February 2019Proceedings of the 12th International Joint Conference on Biomedical Engineering Systems and Technologies, Vol. 3. pp. 90-100., (10.5220/0007397200900100)