Professor Sir Michael Owen

BSc, MB ChB, PhD, FRCPsych, FMedSci, FLSW

2025

• Dennison, C. A. et al. 2025. Early manifestations of neurodevelopmental copy number variants in children: A population-based investigation. Biological Psychiatry (10.1016/j.biopsych.2025.03.004)
• Ali, N. M. et al. 2025. Comparison of autism domains across thirty rare variant genotypes. EBioMedicine 112, article number: 105521. (10.1016/j.ebiom.2024.105521)
• O'Connell, K. et al. 2025. Genomics yields biological and phenotypic insights into bipolar disorder. Biological Psychiatry (10.1038/s41586-024-08468-9)
• Panagiotaropoulou, G. et al. 2025. Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analyses.. The British Journal of Psychiatry (10.1192/bjp.2024.125)
• Owen, M., Bray, N., Walters, J. and O'Donovan, M. 2025. Genomics of major mental illness. Nature Reviews Genetics
• Katzourou, I. et al. 2025. The contributions of common and rare genetic variation to different measures of mood and anxiety disorder in UK Biobank. BJPsych Open

2024

• Woolway, G. E. et al. 2024. Assessing the validity of a self-reported clinical diagnosis of schizophrenia. Schizophrenia 10(1), article number: 99. (10.1038/s41537-024-00526-5)
• Benger, L., LINC Consortium, ., Holmans, P., Owen, M., Mon-Williams, M., Katzourou, I. and Van den Bree, M. 2024. Adverse childhood experiences and multimorbidity of internalising and cardiometabolic conditions in an older-age population. Presented at: International Population Data Linkage Conference, Chicago, USA, 15-18 September 2025Conference Proceedings for International Population Data Linkage Conference, Vol. 9. Vol. 5. Swansea University pp. 133., (10.23889/ijpds.v9i5.2617)
• Legge, S. E. et al. 2024. Genetic and phenotypic features of Schizophrenia in the UK Biobank. JAMA Psychiatry 81, pp. 681-690. (10.1001/jamapsychiatry.2024.0200)
• Trastulla, L. et al. 2024. Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nature Communications 15, article number: 5534. (10.1038/s41467-024-49338-2)
• Hall, J. H. et al. 2024. Irritability in young people with copy number variants associated with neurodevelopmental disorders (ND-CNVs). Translational Psychiatry 14(1), article number: 259. (10.1038/s41398-024-02975-z)
• Stevenson-Hoare, J. et al. 2024. Severe psychiatric disorders are associated with increased risk of dementia. BMJ Mental Health 27(1), article number: e301097. (10.1136/bmjment-2024-301097)
• Haddon, J. E. et al. 2024. Linking haploinsufficiency of the autism- and schizophrenia-associated gene Cyfip1 with striatal-limbic-cortical network dysfunction and cognitive inflexibility. Translational Psychiatry 14(1), article number: 256. (10.1038/s41398-024-02969-x)
• Cabezas De La Fuente, D. et al. 2024. Impaired oxysterol-liver X receptor signaling underlies aberrant cortical neurogenesis in a human stem cell model of neurodevelopmental disorder. Cell Reports 43(3), article number: 113946. (10.1016/j.celrep.2024.113946)
• Kopal, J. et al. 2024. Using rare genetic mutations to revisit structural brain asymmetry. Nature Communications 15(1), article number: 2639. (10.1038/s41467-024-46784-w)
• Kappel, D. et al. 2024. Rare variants in pharmacogenes influence clozapine metabolism in individuals with schizophrenia. European Neuropsychopharmacology 80, pp. 47-54. (10.1016/j.euroneuro.2023.12.007)
• Tandon, R. et al. 2024. The schizophrenia syndrome, circa 2024: What we know and how that informs its nature. Schizophrenia Research 264, pp. 1-28. (10.1016/j.schres.2023.11.015)
• Doherty, J. L. et al. 2024. Atypical cortical networks in children at high-genetic risk of psychiatric and eurodevelopmental disorders. Neuropsychopharmacology 49, pp. 368-376. (10.1038/s41386-023-01628-x)
• Boen, R. et al. 2024. Beyond the global brain differences: Intra-individual variability differences in 1q21.1 distal and 15q11.2 BP1-BP2 deletion carriers. Biological Psychiatry 95(2), pp. 147-160. (10.1016/j.biopsych.2023.08.018)
• Peall, K. J., Owen, M. J. and Hall, J. 2024. Rare genetic brain disorders with overlapping neurological and psychiatric phenotypes. Nature Reviews Neurology 20(1), pp. 7-21. (10.1038/s41582-023-00896-x)
• Ge, R. et al. 2024. Source‐based morphometry reveals structural brain pattern abnormalities in 22q11.2 deletion syndrome. Human Brain Mapping 45(1), article number: e26553. (10.1002/hbm.26553)
• Owen, M. J. and O'Donovan, M. C. 2024. The genetics of cognition in schizophrenia. Genomic Psychiatry (10.61373/gp024i.0040)

2023

• Wang, S. et al. 2023. Rare X-linked variants carry predominantly male risk in Autism, Tourette Syndrome, and ADHD. Nature Communications 14, article number: 8077. (10.1038/s41467-023-43776-0)
• Chilvers, C. and Owen, M. J. 2023. Mental Health Research, shared goals. Journal of Mental Health 32, article number: 1017. (10.1080/09638237.2021.1898562)
• Caseras, X., Legge, S., Bracher-Smith, M., Anney, R., Owen, M., Escott-Price, V. and Kirov, G. 2023. Copy Number Variants increasing risk for schizophrenia: shared and distinct effects on brain morphometry and cognitive performance. Biological Psychiatry: Global Open Science 3(4), pp. 902-911. (10.1016/j.bpsgos.2022.10.006)
• Lock, S. K. et al. 2023. Mediation and longitudinal analysis to interpret the association between clozapine pharmacokinetics, pharmacogenomics, and absolute neutrophil count. Schizophrenia 9, article number: 74. (10.1038/s41537-023-00404-6)
• Doherty, A., O'Donovan, M., Hamshere, M., Jones, I., Owen, M. and Walters, J. 2023. Genome-wide association study meta-analysis of suicide attempt identifies twelve genome-wide significant loci and implicates genetic risks for specific health factors. The American Journal of Psychiatry 180(10), pp. 723-738. (10.1176/appi.ajp.21121266)
• Owen, M., Legge, S., Rees, E., Walters, J. and O'Donovan, M. 2023. Genomic findings in schizophrenia and their implications. Molecular Psychiatry 28, pp. 3638-3647. (10.1038/s41380-023-02293-8)
• Kumar, K. et al. 2023. Subcortical brain alterations in carriers of genomic copy number variants. The American Journal of Psychiatry 180(9), pp. 685-698. (10.1176/appi.ajp.20220304)
• Le Guen, Y. et al. 2023. Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes. Proceedings of the National Academy of Sciences 120(36), article number: e2302720120. (10.1073/pnas.2302720120)
• Ollà, I. et al. 2023. Pathogenic mis-splicing of CPEB4 in schizophrenia. Biological Psychiatry 94(4), pp. 341-351. (10.1016/j.biopsych.2023.03.010)
• Zhao, Y. et al. 2023. Chromatin regulators in the TBX1 network confer risk for conotruncal heart defects in 22q11.2DS. npj Genomic Medicine 8(1), article number: 17. (10.1038/s41525-023-00363-y)
• Allardyce, J. et al. 2023. Specificity of polygenic signatures across symptom dimensions in bipolar disorder: an analysis of UK Bipolar Disorder Research Network data. The Lancet Psychiatry 10(8), pp. 623-631. (10.1016/S2215-0366(23)00186-4)
• Kopal, J. et al. 2023. Rare CNVs and phenome-wide profiling highlight brain structural divergence and phenotypical convergence. Nature Human Behaviour 7, pp. 1001-1007. (10.1038/s41562-023-01541-9)
• Chawner, S. J. et al. 2023. Neurodevelopmental dimensional assessment of young children at high genomic risk of neuropsychiatric conditions. JCPP Advances 3(2), article number: e12162. (10.1002/jcv2.12162)
• Niarchou, M. et al. 2023. Psychopathology in mothers of children with pathogenic copy number variants. Journal of Medical Genetics 60, pp. 706-711. (10.1136/jmg-2022-108752)
• Rogdaki, M. et al. 2023. Striatal dopaminergic alterations in individuals with copy number variants at the 22q11.2 genetic locus and their implications for psychosis risk: a [18F]-DOPA PET study. Molecular Psychiatry 28, pp. 1995-2006. (10.1038/s41380-021-01108-y)
• Adams, R. L. et al. 2023. Psychopathology in adults with copy number variants. Psychological Medicine 53(7), pp. 3142-3149. (10.1017/S0033291721005201)
• Lin, J. et al. 2023. Rare coding variants as risk modifiers of the 22q11.2 deletion implicate postnatal cortical development in syndromic schizophrenia. Molecular Psychiatry 28, pp. 2071-2080. (10.1038/s41380-023-02009-y)
• Chen, Z. et al. 2023. The contribution of Neanderthal introgression and natural selection to neurodegenerative diseases. Neurobiology of Disease 180, article number: 106082. (10.1016/j.nbd.2023.106082)
• Moreau, C. A. et al. 2023. Brain functional connectivity mirrors genetic pleiotropy in psychiatric conditions. Brain 146(4), pp. 1686-1696. (10.1093/brain/awac315)
• Lynham, A. J. et al. 2023. DRAGON-Data: A platform and protocol for integrating genomic and phenotypic data across large psychiatric cohorts. BJPsych Open 9(2), article number: e32. (10.1192/bjo.2022.636)
• Pardinas, A. F. et al. 2023. Pharmacokinetics and pharmacogenomics of clozapine in an ancestrally diverse sample: a longitudinal analysis and genome-wide association study using UK clinical monitoring data. The Lancet Psychiatry 10(3), pp. 209-219. (10.1016/S2215-0366(23)00002-0)
• Rammos, A., Kirov, G., Hubbard, L., Walters, J., Holmans, P., Owen, M. and Rees, E. 2023. Family-based analysis of the contribution of rare and common genetic variants to school performance in schizophrenia. Molecular Psychiatry 28, pp. 2081-2087. (10.1038/s41380-023-02013-2)
• Dimitriadis, S. I. et al. 2023. Genetic risk for schizophrenia is associated with increased proportion of indirect connections in brain networks revealed by a semi-metric analysis: evidence from population sample stratified for polygenic risk. Cerebral Cortex 33(6), pp. 2997-3011. (10.1093/cercor/bhac256)
• Liu, D. et al. 2023. Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations. Nature Genetics 55, pp. 369-376. (10.1038/s41588-023-01305-1)
• Owen, M. J. 2023. Genomic insights into schizophrenia. Royal Society Open Science 10(2), article number: 230125. (10.1098/rsos.230125)
• Moreau, C. A. et al. 2023. Genetic heterogeneity shapes brain connectivity in psychiatry. Biological Psychiatry 93(1), pp. 45-58. (10.1016/j.biopsych.2022.08.024)
• Kappel, D. B. et al. 2023. Genomic stratification of clozapine prescription patterns using schizophrenia polygenic scores. Biological Psychiatry 93, pp. 149-156. (10.1016/j.biopsych.2022.07.014)
• Wolstencroft, J. et al. 2023. Mental health impact of autism on families of children with intellectual and developmental disabilities of genetic origin. JCPP Advances, article number: e12128. (10.1002/jcv2.12128)
• Chawner, S. J. R. A., Evans, A., IMAGINE-ID consortium, ., Williams, N., Owen, M. J., Hall, J. and van den Bree, M. B. M. 2023. Sleep disturbance as a transdiagnostic marker of psychiatric risk in children with neurodevelopmental risk genetic conditions. Translational Psychiatry 13, article number: 7. (10.1038/s41398-022-02296-z)

2022

• Owen, M. J. 2022. The contribution of the Rüdin school to psychiatric genetics: the light and the darkness. Schizophrenia Bulletin: The Journal of Psychoses and Related Disorders 48(Supple), pp. S1-S3. (10.1093/schbul/sbac119)
• Alsaqati, M. et al. 2022. NRSF/REST lies at the intersection between epigenetic regulation, miRNA-mediated gene control and neurodevelopmental pathways associated with Intellectual disability (ID) and Schizophrenia. Translational Psychiatry 12, article number: 438. (10.1038/s41398-022-02199-z)
• Woolway, G. et al. 2022. Schizophrenia polygenic risk and experiences of childhood adversity: a systematic review and meta-analysis. Schizophrenia Bulletin 48(5), pp. 967-980. (10.1093/schbul/sbac049)
• Chawner, S. and Owen, M. 2022. Autism: a model of neurodevelopmental diversity informed by genomics. Frontiers in Psychiatry 13, article number: 981691. (10.3389/fpsyt.2022.981691)
• Wolstencroft, J. et al. 2022. Neuropsychiatric risk in children with intellectual disability of genetic origin: IMAGINE, a UK national cohort study. The Lancet Psychiatry 9(9), pp. 715-724. (10.1016/S2215-0366(22)00207-3)
• Bracher-Smith, M. et al. 2022. Machine learning for prediction of schizophrenia using genetic and demographic factors in the UK Biobank. Schizophrenia Research 246, pp. 156-164. (10.1016/j.schres.2022.06.006)
• Richards, A. et al. 2022. Genetic liabilities differentiating bipolar disorder, schizophrenia and major depression and phenotypic heterogeneity in bipolar disorder. JAMA Psychiatry 79(10), pp. 1032-1039. (10.1001/jamapsychiatry.2022.2594)
• Donnelly, N. A. et al. 2022. Sleep EEG in young people with 22q11.2 deletion syndrome: A cross-sectional study of slow-waves, spindles and correlations with memory and neurodevelopmental symptoms. eLife 11, article number: e75482. (10.7554/elife.75482)
• Creeth, H. D. J. et al. 2022. Ultrarare coding variants and cognitive function in schizophrenia. JAMA Psychiatry 79(10), pp. 963-970. (10.1001/jamapsychiatry.2022.2289)
• Fiksinski, A. M. et al. 2022. A normative chart for cognitive development in a genetically selected population. Neuropsychopharmacology 47(7), pp. 1379–1386. (10.1038/s41386-021-00988-6)
• Palmer, D. et al. 2022. Exome sequencing in bipolar disorder reveals AKAP11 as a risk gene shared with schizophrenia. Nature Genetics (10.1038/s41588-022-01034-x)
• Owen, M. and Legge, S. 2022. The nature of schizophrenia: as broad as it is long. Schizophrenia Research 242, pp. 109-112. (10.1016/j.schres.2021.10.012)
• Bellenguez, C. et al. 2022. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature Genetics 54(4), pp. 412-436. (10.1038/s41588-022-01024-z)
• Trubetskoy, V. et al. 2022. Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia. Nature 604, pp. 502-508. (10.1038/s41586-022-04434-5)
• Singh, T., Schizophrenia Exome Meta-Analysis (SCHEMA) Consortium, ., Kirov, G., Rees, E., Walters, J., Owen, M. and O'Donovan, M. 2022. Rare coding variants in ten genes confer substantial risk for schizophrenia. Nature 604, pp. 509-516. (10.1038/s41586-022-04556-w)
• Cunningham, A. C., Hall, J., Owen, M. and van den Bree, M. B. M. 2022. Assessment of emotions and behaviour by the Developmental Behaviour Checklist in young people with neurodevelopmental CNVs. Psychological Medicine 52(3), pp. 574-586. (10.1017/S0033291720002330)
• Chapman, G. et al. 2022. Using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion and duplication syndrome. Molecular Psychiatry 27, pp. 819-830. (10.1038/s41380-021-01182-2)
• Wolstencroft, J. et al. 2022. Neuropsychiatric risk in children with intellectual disability of genetic origin: IMAGINE - The UK National Cohort Study. [Online]. papers.SSRN.com: Elsevier. (10.2139/ssrn.4028542) Available at: http://dx.doi.org/10.2139/ssrn.4028542
• Mullins, N. et al. 2022. Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors. Biological Psychiatry 91(3), pp. 313-327. (10.1016/j.biopsych.2021.05.029)
• Jones, H. J. et al. 2022. Examining pathways between genetic liability for schizophrenia and patterns of tobacco and cannabis use in adolescence. Psychological Medicine 52(1), pp. 132-139. (10.1017/S0033291720001798)
• Vassos, E. et al. 2022. Lack of support for the genes by early environment interaction hypothesis in the pathogenesis of schizophrenia. Schizophrenia Bulletin 48(1), pp. 20-26. (10.1093/schbul/sbab052)
• Westacott, L. J. et al. 2022. Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder. Brain, Behavior, and Immunity 99, pp. 70-82. (10.1016/j.bbi.2021.09.005)
• Sanders, B. et al. 2022. Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants. Nature Communications 13(1), article number: 27. (10.1038/s41467-021-27601-0)
• Pardinas, A. et al. 2022. Interaction testing and polygenic risk scoring to estimate the contribution of common genetic variants to treatment resistance in schizophrenia. JAMA Psychiatry 79(3), pp. 260-269. (10.1001/jamapsychiatry.2021.3799)

2021

• Dimitriadis, S. I. et al. 2021. Global brain flexibility during working memory is reduced in a high genetic risk group for schizophrenia. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 6(12), pp. 1176-1184. (10.1016/j.bpsc.2021.01.007)
• Di Florio, A. et al. 2021. Post-partum psychosis and its association with bipolar disorder in the UK: a case-control study using polygenic risk scores. The Lancet Psychiatry 8(12), pp. 1045-1052. (10.1016/S2215-0366(21)00253-4)
• Kalman, J. L. et al. 2021. Characterisation of age and polarity at onset in bipolar disorder. The British Journal of Psychiatry 219(6), pp. 659-669. (10.1192/bjp.2021.102)
• Pardinas, A. F., Owen, M. J. and Walters, J. T. 2021. Pharmacogenomics: A road ahead for precision medicine in psychiatry. Neuron 109(24), pp. 3914-3929. (10.1016/j.neuron.2021.09.011)
• Dimitriadis, S. I. et al. 2021. Genetic risk for schizophrenia is associated with altered visually-induced gamma band activity: evidence from a population sample stratified polygenic risk. Translational Psychiatry 11, article number: 592. (10.1038/s41398-021-01678-z)
• Jia, X. et al. 2021. Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. Molecular Psychiatry 26, pp. 5239-5250. (10.1038/s41380-020-01006-9)
• Dennison, C. et al. 2021. Risk factors, clinical features, and polygenic risk scores in schizophrenia and schizoaffective disorder depressive-type. Schizophrenia Bulletin 47(5), pp. 1375-1384. (10.1093/schbul/sbab036)
• Clifton, N. E. et al. 2021. Developmental profile of psychiatric risk associated with voltage-gated cation channel activity. Biological Psychiatry 90(6) (10.1016/j.biopsych.2021.03.009)
• Rees, E. et al. 2021. Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations. Nature Communications 12, article number: 5353. (10.1038/s41467-021-25532-4)
• Cleynen, I. et al. 2021. Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion. Molecular Psychiatry, pp. 4496-4510. (10.1038/s41380-020-0654-3)
• Legge, S. et al. 2021. Associations between schizophrenia polygenic liability, symptom dimensions, and cognitive ability in schizophrenia. JAMA Psychiatry 78(10), pp. 1143-1151. (10.1001/jamapsychiatry.2021.1961)
• Clifton, N. E. et al. 2021. Genetic association of FMRP targets with psychiatric disorders. Molecular Psychiatry 26, pp. 2977-2990. (10.1038/s41380-020-00912-2)
• Forsyth, J. K. et al. 2021. Prioritizing genetic contributors to cortical alterations in 22q11.2 deletion syndrome using imaging transcriptomics. Cerebral Cortex 31(7), pp. 3285-3298. (10.1093/cercor/bhab008)
• Modenato, C. et al. 2021. Effects of eight neuropsychiatric copy number variants on human brain structure. Translational Psychiatry 11(1), article number: 399. (10.1038/s41398-021-01490-9)
• Hubbard, L. et al. 2021. Rare copy number variations are associated with poorer cognition in schizophrenia. Biological Psychiatry 90(1), pp. 28-34. (10.1016/j.biopsych.2020.11.025)
• Byrne, E. et al. 2021. Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders. Molecular Psychiatry 26, pp. 2070-2081. (10.1038/s41380-020-0705-9)
• Hall, L. S. et al. 2021. Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders. Molecular Psychiatry 26, pp. 2082-2088. (10.1038/s41380-020-0743-3)
• Amare, A. T. et al. 2021. Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular Psychiatry 26, pp. 2457-2470. (10.1038/s41380-020-0689-5)
• Tigaret, C. M. et al. 2021. Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by hemizygosity of the psychiatric risk gene Cacna1c. Molecular Psychiatry 26, pp. 1748-1760. (10.1038/s41380-020-01001-0)
• Mullins, N. et al. 2021. Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics 53, pp. 817-829. (10.1038/s41588-021-00857-4)
• Owen, M. J. and Williams, N. M. 2021. Explaining the missing heritability of psychiatric disorders. World Psychiatry 20(2), pp. 294-295. (10.1002/wps.20870)
• Peterson, R. E. et al. 2021. Genome-wide analyses of smoking behaviors in schizophrenia: findings from the Psychiatric Genomics Consortium. Journal of Psychiatric Research 137, pp. 215-225. (10.1016/j.jpsychires.2021.02.027)
• Haan, N., Westacott, L. J., Carter, J., Owen, M. J., Gray, W. P., Hall, J. and Wilkinson, L. S. 2021. Haploinsufficiency of the schizophrenia and autism risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms. Translational Psychiatry 11(1), article number: 313. (10.1038/s41398-021-01415-6)
• Willcocks, I. et al. 2021. Clozapine metabolism is associated with absolute neutrophil count in individuals with treatment-resistant schizophrenia. Frontiers in Pharmacology 12, article number: 658734. (10.3389/fphar.2021.658734)
• Dennison, C. A. et al. 2021. Association of genetic liability for psychiatric disorders with accelerometer-assessed physical activity in the UK Biobank. PLoS ONE 16(3), article number: e0249189. (10.1371/journal.pone.0249189)
• Linden, S. C. et al. 2021. The psychiatric phenotypes of 1q21 distal deletion and duplication. Translational Psychiatry 11, article number: 105. (10.1038/s41398-021-01226-9)
• Cunningham, A., Hall, J., Owen, M. and Van den Bree, M. 2021. Coordination difficulties, IQ and psychopathology in children with high-risk Copy Number Variants. Psychological Medicine 51(2), pp. 290-299. (10.1017/S0033291719003210)
• Owen, M. J. and O'Donovan, M. C. 2021. Large-scale genomics: a paradigm shift in psychiatry?. Biological Psychiatry 89, pp. 5-7. (10.1016/j.biopsych.2020.01.017)
• Chawner, S. et al. 2021. A genetics-first approach to dissecting the heterogeneity of autism: phenotypic comparison of autism risk copy number variants. American Journal of Psychiatry 178(1), pp. 77-86. (10.1176/appi.ajp.2020.20010015)
• Sønderby, I. E., Hall, J., Owen, M., Van Den Bree, M., Linden, D., Silva, A. and Doherty, J. 2021. 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans. Translational Psychiatry 11, article number: 182. (10.1038/s41398-021-01213-0)

2020

• Davies, R. et al. 2020. Using common genetic variation to examine phenotypic expression and risk prediction in 22q11.2 Deletion Syndrome. Nature Medicine 26, pp. 1912-1918. (10.1038/s41591-020-1103-1)
• Villalon-Reina, J. et al. 2020. Altered white matter microstructure in 22q11.2 deletion syndrome: a multi-site diffusion tensor imaging study. Molecular Psychiatry 25, pp. 2818-2831. (10.1038/s41380-019-0450-0)
• Kendall, K. M. et al. 2020. Impact of schizophrenia genetic liability on the association between schizophrenia and physical illness: a data linkage study. BJPsych Open 6(6), article number: e139. (10.1192/bjo.2020.42)
• Legge, S. E. et al. 2020. The Duffy-null genotype and risk of infection. Human Molecular Genetics 29(20), pp. 3341-3349. (10.1093/hmg/ddaa208)
• Jones, H. J. et al. 2020. A Mendelian randomization study of the causal association between anxiety phenotypes and schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 183(6), pp. 360-369. (10.1002/ajmg.b.32808)
• Dima, D. C. et al. 2020. Electrophysiological network alterations in adults with copy number variants associated with high neurodevelopmental risk. Translational Psychiatry 10, article number: 324. (10.1038/s41398-020-00998-w)
• Sun, D. et al. 2020. Large-scale mapping of cortical alterations in 22q11.2 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size. Molecular Psychiatry 25, pp. 1822-1834. (10.1038/s41380-018-0078-5)
• Coleman, J. R. I. et al. 2020. Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Molecular Psychiatry 25, pp. 1430-1446. (10.1038/s41380-019-0546-6)
• Cunningham, A., Fung, W., Massey, T., Hall, J., Owen, M., Van Den Bree, M. and Peall, K. 2020. Movement disorder phenotypes in children with 22q11.2 deletion syndrome. Movement Disorders 35(7), pp. 1272-1274. (10.1002/mds.28078)
• Akingbuwa, W. A. et al. 2020. Genetic associations between childhood psychopathology and adult depression and associated traits in 42 998 individuals. JAMA Psychiatry 77(7), pp. 715-728. (10.1001/jamapsychiatry.2020.0527)
• Ching, C. R. et al. 2020. Mapping subcortical brain alterations in 22q11.2 deletion syndrome: effects of seletion size and convergence with idiopathic neuropsychiatric illness. American Journal of Psychiatry 177(7), pp. 589-600. (10.1176/appi.ajp.2019.19060583)
• Lee, S. C. et al. 2020. Area deprivation, urbanicity, severe mental illness and social drift — a population-based linkage study using routinely collected primary and secondary care data. Schizophrenia Research 220, pp. 130-140. (10.1016/j.schres.2020.03.044)
• Legge, S. et al. 2020. Clinical indicators of treatment-resistant psychosis. British Journal of Psychiatry 216(5), pp. 259-266. (10.1192/bjp.2019.120)
• Martin, J. et al. 2020. A brief report: de novo copy number variants in children with attention deficit hyperactivity disorder. Translational Psychiatry 10, article number: 135. (10.1038/s41398-020-0821-y)
• Moulding, H., Bartsch, U., Hall, J., Jones, M., Linden, D., Owen, M. and Van Den Bree, M. 2020. Sleep problems and associations with psychopathology and cognition in young people with 22q11.2 deletion syndrome (22q11.2DS). Psychological Medicine 50, pp. 1191-1202. (10.1017/S0033291719001119)
• Foley, C. et al. 2020. Identifying schizophrenia patients who carry pathogenic genetic copy number variants using standard clinical assessment: retrospective cohort study. British Journal of Psychiatry 216(5), pp. 275-279. (10.1192/bjp.2019.262)
• van der Meer, D. et al. 2020. Association of copy number variation of the 15q11.2 BP1-BP2 region with cortical and subcortical morphology and cognition. JAMA Psychiatry 77(4), pp. 420-430. (10.1001/jamapsychiatry.2019.3779)
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2019

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2018

• Brieva, J. et al. 2018. Alternative diffusion anisotropy measures for the investigation of white matter alterations in 22q11.2 deletion syndrome. Presented at: 14th International Symposium on Medical Information Processing and Analysis,, Mazatlán, Mexico, 24-26 October 2018 Presented at Romero, E., Lepore, N. and Brieva, J. eds.14th International Symposium on Medical Information Processing and Analysis, Vol. 10975. Proceedings of SPIE Bellingham, Washington: SPIE pp. 51., (10.1117/12.2513788)
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2017

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2016

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2015

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• Green, E. K. et al. 2015. Copy number variation in bipolar disorder. Molecular Psychiatry 21(1), pp. 89-93. (10.1038/mp.2014.174)
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• Tansey, K. E., Owen, M. J. and O'Donovan, M. C. 2015. Schizophrenia genetics: Building the foundations of the future. Schizophrenia Bulletin 41(1), pp. 15-19. (10.1093/schbul/sbu162)
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2014

• Peall, K. J. et al. 2014. SGCE and myoclonus dystonia: motor characteristics, diagnostic criteria and clinical predictors of genotype. Journal of Neurology 261(12), pp. 2296-2304. (10.1007/s00415-014-7488-3)
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• Niarchou, M., Zammit, S., van Goozen, S. H. M., Thapar, A., Tierling, H. M., Owen, M. J. and van den Bree, M. B. M. 2014. Psychopathology and cognition in children with 22q11.2 deletion syndrome. British Journal of Psychiatry 204(1), pp. 46-54. (10.1192/bjp.bp.113.132324)

2013

• Green, E. K. et al. 2013. Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample. Molecular Psychiatry 18(12), pp. 1302-1307. (10.1038/mp.2012.142)
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• Niarchou, M., Zammit, S., Walters, J. T. R., Lewis, G., Owen, M. J. and van den Bree, M. B. 2013. Defective processing speed and nonclinical psychotic experiences in children: longitudinal analyses in a large birth cohort. American Journal of Psychiatry 170(5), pp. 550-557. (10.1176/appi.ajp.2012.12060792)
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2012

• Hollingworth, P. et al. 2012. Genome-wide association study of Alzheimer's disease with psychotic symptoms. Molecular Psychiatry 17(12), pp. 1316-1327. (10.1038/mp.2011.125)
• Eyre, S. et al. 2012. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nature Genetics 44(12), pp. 1336-1340. (10.1038/ng.2462)
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• Williams, H. J., Georgieva, L., Dwyer, S. L., Kirov, G., Owen, M. J. and O'Donovan, M. C. 2012. Absence of de novo point mutations in exons of GRIN2B in a large schizophrenia trio sample [Letter]. Schizophrenia Research 141(2-3), pp. 274-276. (10.1016/j.schres.2012.08.024)
• O'Donovan, M. C., Owen, M. J., Walters, J. T. R., Irish Schizophrenia Genomics Consortium, . and Wellcome Trust Case Control Consortium 2, . 2012. Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia. Biological psychiatry 72(8), pp. 620-628. (10.1016/j.biopsych.2012.05.035)
• Sellers, R. et al. 2012. Risk of psychopathology in adolescent offspring of mothers with psychopathology and recurrent depression. British Journal of Psychiatry 202(2), pp. 108-114. (10.1192/bjp.bp.111.104984)
• Fromer, M. et al. 2012. Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth. American Journal of Human Genetics 91(4), pp. 597-607. (10.1016/j.ajhg.2012.08.005)
• Power, R. A. et al. 2012. Dissecting the genetic heterogeneity of depression through age at onset. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 159B(7), pp. 859-868. (10.1002/ajmg.b.32093)
• Levinson, D. F. et al. 2012. Genome-wide association study of multiplex schizophrenia pedigrees. American Journal of Psychiatry 169(9), pp. 963-973. (10.1176/appi.ajp.2012.11091423)
• Hamilton, G. et al. 2012. The role of ECE1 variants in cognitive ability in old age and Alzheimer's disease risk. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 159B(6), pp. 696-709. (10.1002/ajmg.b.32073)
• Thapar, A. K., Heron, J., Bevan Jones, R., Owen, M. J., Lewis, G. and Zammit, S. 2012. Trajectories of change in self-reported psychotic-like experiences in childhood and adolescence. Schizophrenia Research 140(1-3), pp. 104-109. (10.1016/j.schres.2012.06.024)
• Owen, M. J. 2012. Implications of genetic findings for understanding schizophrenia. Schizophrenia Bulletin 38(5), pp. 904-907. (10.1093/schbul/sbs103)
• Owen, M. J. 2012. The origins of schizophrenia [Review]. British Journal of Psychiatry 201(2), pp. 162. (10.1192/bjp.bp.111.107300)
• Shi, H. et al. 2012. Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS). Neurobiology of Aging 33(8), article number: 1849.e5. (10.1016/j.neurobiolaging.2012.02.014)
• Hamilton, G. et al. 2012. Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus. Neurobiology of Aging 33(8), article number: 1848.e1. (10.1016/j.neurobiolaging.2012.02.005)
• Escott-Price, V., Schmidt, K. M., Vedernikov, A., Owen, M. J., Craddock, N. J., Holmans, P. A. and O'Donovan, M. C. 2012. Permutation-based approaches do not adequately allow for linkage disequilibrium in gene-wide multi-locus association analysis. European Journal of Human Genetics 20(8), pp. 890-896. (10.1038/ejhg.2012.8)
• Derks, E. M. et al. 2012. Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: A polygenic risk score analysis. PLoS ONE 7(6), article number: e37852. (10.1371/journal.pone.0037852)
• Peall, K. J. et al. 2012. Myoclonus dystonia syndrome: SGCE mutations and psychiatric disease [Abstract]. Journal of Neurology 259, pp. S30-S30.
• Fowler, T., Zammit, S., Owen, M. J. and Rasmussen, F. 2012. A population-based study of shared genetic variation between premorbid IQ and psychosis among male twin pairs and sibling pairs from Sweden. Archives of General Psychiatry 69(5), pp. 460-466. (10.1001/archgenpsychiatry.2011.1370)
• Rees, E., Kirov, G., O'Donovan, M. C. and Owen, M. J. 2012. De Novo mutation in schizophrenia. Schizophrenia Bulletin 38(3), pp. 377-381. (10.1093/schbul/sbs047)
• Hudson, G. et al. 2012. No consistent evidence for association between mtDNA variants and Alzheimer disease. Neurology 78(14), pp. 1038-1042. (10.1212/WNL.0b013e31824e8f1d)
• Owen, M. J. 2012. Intellectual disability and major psychiatric disorders: a continuum of neurodevelopmental causality. British Journal of Psychiatry 200(4), pp. 268-269. (10.1192/bjp.bp.111.105551)
• Keller, M. C. et al. 2012. Runs of homozygosity implicate autozygosity as a schizophrenia risk factor. Plos Genetics 8(4), article number: e1002656. (10.1371/journal.pgen.1002656)
• Håvik, B. et al. 2012. DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder. PLoS ONE 7(4), pp. e35424. (10.1371/journal.pone.0035424)
• Grozeva, D. et al. 2012. Independent estimation of the frequency of rare CNVs in the UK population confirms their role in schizophrenia. Schizophrenia Research 135(1-3), pp. 1-7. (10.1016/j.schres.2011.11.004)
• Lambert, J. C. et al. 2012. Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease. Molecular Psychiatry 18, pp. 461-470. (10.1038/mp.2012.14)
• Economou, A. et al. 2012. The health informatics cohort enhancement project (HICE): using routinely collected primary care data to identify people with a lifetime diagnosis of psychotic disorder. BMC Research Notes 5(1), pp. 95-100. (10.1186/1756-0500-5-95)
• Kirov, G. et al. 2012. De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Molecular Psychiatry 17(2), pp. 142-153. (10.1038/mp.2011.154)
• Jia, P. et al. 2012. A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia. Journal of Medical Genetics 49(2), pp. 96-103. (10.1136/jmedgenet-2011-100397)
• Richards, A. et al. 2012. Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain. Molecular Psychiatry 17(2), pp. 193-201. (10.1038/mp.2011.11)
• Stergiakouli, E. et al. 2012. Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD. American Journal of Psychiatry 169(2), pp. 186-194. (10.1176/appi.ajp.2011.11040551)
• Williams, N. M. et al. 2012. Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3. American Journal of Psychiatry 169(2), pp. 195-204. (10.1176/appi.ajp.2011.11060822)
• Gerrish, A. et al. 2012. The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's Disease. Journal of Alzheimer's Disease 28(2), pp. 377-387. (10.3233/JAD-2011-110824)
• Sullivan, P., Craddock, N. J., O'Donovan, M. C. and Owen, M. J. 2012. Don't give up on GWAS [Letter]. Molecular Psychiatry 17(1), pp. 2-3. (10.1038/mp.2011.94)
• Proitsi, P. et al. 2012. Association of serotonin and dopamine gene pathways with behavioral subphenotypes in dementia. Neurobiology of Aging 33(4), pp. 791-803. (10.1016/j.neurobiolaging.2010.06.011)
• Fisher, H. L. et al. 2012. Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depression. Journal of Affective Disorders 136(1-2), pp. 189-193. (10.1016/j.jad.2011.09.016)
• Doherty, J. L., O'Donovan, M. C. and Owen, M. J. 2012. Recent genomic advances in schizophrenia. Clinical Genetics 81(2), pp. 103-109. (10.1111/j.1399-0004.2011.01773.x)
• Baig, S., Palmer, L. E., Owen, M. J., Williams, J., Kehoe, P. G. and Love, S. 2012. Clusterin mRNA and protein in Alzheimer's disease. Journal of Alzheimer's Disease 28(2), pp. 337-344. (10.3233/JAD-2011-110473)

2011

• Hinney, A. et al. 2011. Genome-wide association study in German patients with attention deficit/hyperactivity disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156(8), pp. 888-897. (10.1002/ajmg.b.31246)
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• Rees, E., Escott-Price, V., Owen, M. J., O'Donovan, M. C. and Kirov, G. 2011. De novo rates and selection of schizophrenia-associated copy number variants. Biological Psychiatry 70(12), pp. 1109-1114. (10.1016/j.biopsych.2011.07.011)
• Zammit, S., Owen, M. J., Evans, J., Heron, J. and Lewis, G. 2011. Cannabis, COMT and psychotic experiences. British Journal of Psychiatry 199(5), pp. 380-385. (10.1192/bjp.bp.111.091421)
• Sklar, P. et al. 2011. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 [Letter]. Nature Genetics 43(10), pp. 977-983. (10.1038/ng.943)
• Ripke, S. et al. 2011. Genome-wide association study identifies five new schizophrenia loci [Letter]. Nature Genetics 43(10), pp. 969-976. (10.1038/ng.940)
• Chen, J. et al. 2011. Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia. Schizophrenia Research 131(1-3), pp. 43-51.
• Escott-Price, V. et al. 2011. An examination of single nucleotide polymorphism selection prioritization strategies for tests of gene-gene interaction. Biological Psychiatry 70(2), pp. 198-203. (10.1016/j.biopsych.2011.01.034)
• Chen, J. et al. 2011. Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia. Schizophrenia Research 131(1-3), pp. 43-51. (10.1016/j.schres.2011.06.023)
• Hollingworth, P. et al. 2011. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nature Genetics 43(5), pp. 429-435. (10.1038/ng.803)
• Williams, H. J. et al. 2011. Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. Molecular Psychiatry 16(4), pp. 429-441. (10.1038/mp.2010.36)
• Stergiakouli, E. et al. 2011. Steroid sulfatase is a potential modifier of cognition in attention deficit hyperactivity disorder. Genes Brain and Behavior 10(3), pp. 334-344. (10.1111/j.1601-183x.2010.00672.x)
• Ingason, A. et al. 2011. Maternally derived microduplications at 15q11-q13: Implication of imprinted genes in psychotic illness. American Journal of Psychiatry 168(4), pp. 408-417. (10.1176/appi.ajp.2010.09111660)
• Ikeda, M. et al. 2011. Genome-Wide Association Study of Schizophrenia in a Japanese Population. Biological Psychiatry 69(5), pp. 472-478. (10.1016/j.biopsych.2010.07.010)
• O'Dushlaine, C. et al. 2011. Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility. Molecular Psychiatry 16(3), pp. 286-292. (10.1038/mp.2010.7)
• Owen, M. J. 2011. Is there a schizophrenia to diagnose? [Editorial]. World Psychiatry 10(1), pp. 34-35. (10.1002/j.2051-5545.2011.tb00007.x)
• Belbin, O. et al. 2011. A multi-center study of ACE and the risk of late-onset Alzheimer's disease. Journal of Alzheimer's Disease 24(3), pp. 587-597. (10.3233/JAD-2011-101914)
• Zuliani, R. et al. 2011. Genetic variants in the ErbB4 gene are associated with white matter integrity. Psychiatry Research: Neuroimaging 191(2), pp. 133-137. (10.1016/j.pscychresns.2010.11.001)
• Reilly, M. P. et al. 2011. Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. The Lancet 377(9763), pp. 383-392. (10.1016/S0140-6736(10)61996-4)
• Williams, H. J. et al. 2011. Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries. Human Molecular Genetics 20(2), pp. 387-391. (10.1093/hmg/ddq471)
• Bridges, M. et al. 2011. Genetic classification of populations using supervised learning. PLoS ONE 6(5), article number: e14802. (10.1371/journal.pone.0014802)
• Hamshere, M. L. et al. 2011. Polygenic dissection of the bipolar phenotype. British Journal of Psychiatry 198(4), pp. 284-288. (10.1192/bjp.bp.110.087866)
• Schosser, A. et al. 2011. P02-217 - COMT in major depression - UK candidate gene association study [Meeting Abstract]. European Psychiatry 26, pp. 813. (10.1016/S0924-9338(11)72518-4)
• Williams, N. M., O'Donovan, M. C., Owen, M. J. and Thapar, A. 2011. Structural variations in attention-deficit hyperactivity disorder - Authors' reply [Letter]. The Lancet 377(9763), pp. 378. (10.1016/S0140-6736(11)60121-9)
• Reitz, C. et al. 2011. Meta-analysis of the association between variants in SORL1 and Alzheimer Disease. Archives of Neurology 68(1), pp. 99-106. (10.1001/archneurol.2010.346)
• Green, E. K. et al. 2011. DISC1 exon 11 rare variants found more commonly in schizoaffective spectrum cases than controls. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156B(4), pp. 490-492. (10.1002/ajmg.b.31187)
• Smith, R. L. et al. 2011. Analysis of neurogranin (NRGN) in schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156B(5), pp. 532-535. (10.1002/ajmg.b.31191)
• Schosser, A. et al. 2011. A follow-up case-control association study of tractable (druggable) genes in recurrent major depression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156(6), pp. 640-650. (10.1002/ajmg.b.31204)
• Sims, R. et al. 2011. No evidence that extended tracts of homozygosity are associated with Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156(7), pp. 764-771. (10.1002/ajmg.b.31216)
• Williams, H. J., Escott-Price, V., Smith, R. L., Dwyer, S. L., Russo, G., Owen, M. J. and O'Donovan, M. C. 2011. Association between TCF4 and schizophrenia does not exert its effect by common nonsynonymous variation or by influencing cis-acting regulation of mRNA expression in adult human brain. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156(7), pp. 781-784. (10.1002/ajmg.b.31219)
• Carroll, L. S., Williams, H. J., Walters, J. T. R., Kirov, G., O'Donovan, M. C. and Owen, M. J. 2011. Mutation screening of the 3q29 microdeletion syndrome candidate genes DLG1 and PAK2 in schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156(7), pp. 844-849. (10.1002/ajmg.b.31231)
• Hamshere, M. L. et al. 2011. Phenotype evaluation and genomewide linkage study of clinical variables in schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156(8), pp. 929-940. (10.1002/ajmg.b.31240)
• Peall, K. J., Waite, A. J., Blake, D. J., Owen, M. J. and Morris, H. R. 2011. Psychiatric disorders, myoclonus dystonia, and the epsilon-sarcoglycan gene: a systematic review. Movement Disorders 26(10), pp. 1939-1942. (10.1002/mds.23791)
• Boot, E. et al. 2011. COMT Val158met genotype and striatal D2/3 receptor binding in adults with 22q11 deletion syndrome. Synapse 65(9), pp. 967-970. (10.1002/syn.20932)
• Cichon, S. et al. 2011. Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. American Journal of Human Genetics 88(3), pp. 372-381. (10.1016/j.ajhg.2011.01.017)
• Hansen, T. et al. 2011. At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia. Biological Psychiatry 70(1), pp. 59-63. (10.1016/j.biopsych.2011.01.031)
• Donohoe, G. et al. 2011. A neuropsychological investigation of the genome wide associated schizophrenia risk variant NRGN rs12807809 [Letter]. Schizophrenia Research 125(2-3), pp. 304-306. (10.1016/j.schres.2010.10.019)
• Proitsi, P. et al. 2011. A Multiple Indicators Multiple Causes (MIMIC) model of Behavioural and Psychological Symptoms in Dementia (BPSD). Neurobiology of Aging 32(3), pp. 434-442. (10.1016/j.neurobiolaging.2009.03.005)
• Steinberg, S. et al. 2011. Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Human Molecular Genetics 20(20), pp. 4076-4081. (10.1093/hmg/ddr325)
• Yosifova, A. et al. 2011. Genome-wide association study on bipolar disorder in the Bulgarian population. Genes, Brain and Behavior 10(7), pp. 789-797. (10.1111/j.1601-183X.2011.00721.x)
• Samaan, Z. et al. 2011. Methylenetetrahydrofolate reductase gene variant (MTHFR C677T) and migraine: a case control study and meta-analysis. BMC Neurology 11, pp. 66-74. (10.1186/1471-2377-11-66)
• Breen, G. et al. 2011. A genome-wide significant linkage for severe depression on chromosome 3: the depression network study. American Journal of Psychiatry 168(8), pp. 840-847. (10.1176/appi.ajp.2011.10091342)
• Schosser, A. et al. 2011. Genomewide association scan of suicidal thoughts and behaviour in major depression. PLoS ONE 6(7), article number: e20690. (10.1371/journal.pone.0020690)
• Owen, M. J., O'Donovan, M. C., Thapar, A. and Craddock, N. J. 2011. Neurodevelopmental hypothesis of schizophrenia. British Journal of Psychiatry 198(3), pp. 173-175. (10.1192/bjp.bp.110.084384)
• Langley, K. et al. 2011. Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants. British Journal of Psychiatry 199(5), pp. 398-403.
• Dwyer, S. L. et al. 2011. Investigation of rare non-synonymous variants at ABCA13 in schizophrenia and bipolar disorder [letter]. Molecular Psychiatry 16(8), pp. 790-791. (10.1038/mp.2011.2)
• Ruderfer, D. M. et al. 2011. A family-based study of common polygenic variation and risk of schizophrenia [Letter]. Molecular Psychiatry 16(9), pp. 887-888. (10.1038/mp.2011.34)
• Rivera, M. et al. 2011. Depressive disorder moderates the effect of the FTO gene on body mass index. Molecular Psychiatry 17(6), pp. 604-611. (10.1038/mp.2011.45)
• Rietschel, M. et al. 2011. Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe. Molecular Psychiatry, pp. 1-12. (10.1038/mp.2011.80)

2010

• Langley, K., Heron, J., O'Donovan, M. C., Owen, M. J. and Thapar, A. 2010. Genotype link with extreme antisocial behavior: The contribution of cognitive pathways. Archives of General Psychiatry 67(12), pp. 1317-1323. (10.1001/archgenpsychiatry.2010.163)
• Carroll, L. S. et al. 2010. Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha. Molecular Psychiatry 15(11), pp. 1101-1111. (10.1038/mp.2009.96)
• Craddock, N. J. et al. 2010. Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype [Corrigendum]. Molecular Psychiatry 15(11), pp. 1121-1121. (10.1038/mp.2010.62)
• Jones, L. et al. 2010. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. PLoS ONE 5(11), article number: e13950. (10.1371/journal.pone.0013950)
• Williams, N. M. et al. 2010. Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis. The Lancet 376(9750), pp. 1401-1408. (10.1016/S0140-6736(10)61109-9)
• Green, E. K. et al. 2010. The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Molecular Psychiatry 15(10), pp. 1016-1022. (10.1038/mp.2009.49)
• Nishikawa, K. et al. 2010. Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation. The Journal of Clinical Investigation 120(10), pp. 3455-3465. (10.1172/JCI42528)
• Allison, D. B. et al. 2010. Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function. PLoS Genetics 6(9), article number: e1001097. (10.1371/journal.pgen.1001097)
• Zammit, S., Owen, M. J. and Lewis, G. 2010. Misconceptions about gene-environment interactions in psychiatry. Evidence Based Mental Health 13(3), pp. 65-68. (10.1136/ebmh.13.3.65)
• Escott-Price, V. et al. 2010. Genetic differences between five European populations. Human Heredity 70(2), pp. 141-149. (10.1159/000313854)
• Walters, J. T. R. et al. 2010. Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia. Archives of General Psychiatry 67(7), pp. 692-700. (10.1001/archgenpsychiatry.2010.81)
• Seshadri, S. et al. 2010. Genome-wide analysis of genetic loci associated with Alzheimer Disease. JAMA - The Journal of the American Medical Association 303(18), pp. 1832-1840. (10.1001/jama.2010.574)
• Grozeva, D. et al. 2010. Rare copy number variants: A point of rarity in genetic risk for bipolar disorder and schizophrenia. Archives of General Psychiatry 67(4), pp. 318-327. (10.1001/archgenpsychiatry.2010.25)
• Craddock, N. J. et al. 2010. Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature 464(7289), pp. 713-720. (10.1038/nature08979)
• Langley, K. et al. 2010. Adolescent clinical outcomes for young people with attention-deficit hyperactivity disorder. British Journal of Psychiatry 196(3), pp. 235-240. (10.1192/bjp.bp.109.066274)
• Craddock, N. J. et al. 2010. Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype. Molecular Psychiatry 15(2), pp. 146-153. (10.1038/mp.2008.66)
• Ikeda, M. et al. 2010. Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches. Biological psychiatry 67(3), pp. 263-269. (10.1016/j.biopsych.2009.08.030)
• Ikeda, M. et al. 2010. Copy number variation in schizophrenia in the Japanese population. Biological Psychiatry 67(3), pp. 283-286. (10.1016/j.biopsych.2009.08.034)
• Schosser, A. et al. 2010. Genome wide association scan of co-morbid anxiety in major depressive disorder (MDD) [Abstract]. International Journal of Psychiatry in Clinical Practice 14(S1), pp. 37.
• Owen, M. J., Craddock, N. J. and O'Donovan, M. C. 2010. Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia. Archives of General Psychiatry 67(7), pp. 667-673. (10.1001/archgenpsychiatry.2010.69)
• Ikeda, M. et al. 2010. Failure to confirm association between PIK4CA and psychosis in 22q11.2 deletion syndrome. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153B(4), pp. 980-982. (10.1002/ajmg.b.31060)
• Cohen-Woods, S. et al. 2010. The Bipolar Association Case-Control Study (BACCS) and meta-analysis: No association with the 5,10-Methylenetetrahydrofolate reductase gene and bipolar disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153B(7), pp. 1298-1304. (10.1002/ajmg.b.31101)
• Green, E. K. et al. 2010. Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153B(7), pp. 1347-1349. (10.1002/ajmg.b.31108)
• Dwyer, S. L., Williams, H., Holmans, P. A., Escott-Price, V., Craddock, N. J., Owen, M. J. and O'Donovan, M. C. 2010. No evidence that rare coding variants in ZNF804A confer risk of schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153B(8), pp. 1411-1416. (10.1002/ajmg.b.31117)
• Talkowski, M. E. et al. 2010. Fine-mapping reveals novel alternative splicing of the dopamine transporter. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153B(8), pp. 1434-1447. (10.1002/ajmg.b.31125)
• Butler, A. W. et al. 2010. A genomewide linkage study on suicidality in major depressive disorder confirms evidence for linkage to 2p12. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153B(8), pp. 1465-1473. (10.1002/ajmg.b.31127)
• Hollingworth, P., Harold, D., Jones, L., Owen, M. J. and Williams, J. 2010. Alzheimer's disease genetics: current knowledge and future challenges. International Journal of Geriatric Psychiatry 26(8), pp. 793-802. (10.1002/gps.2628)
• Lupton, M. K. et al. 2010. Education, occupation and retirement age effects on the age of onset of Alzheimer's disease. International Journal of Geriatric Psychiatry 25(1), pp. 30-36. (10.1002/gps.2294)
• Neale, B. M. et al. 2010. Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder. Journal of the American Academy of Child & Adolescent Psychiatry 49(9), pp. 884-897. (10.1016/j.jaac.2010.06.008)
• Blake, D. J., Forrest, M., Chapman, R. M., Tinsley, C. L., O'Donovan, M. C. and Owen, M. J. 2010. TCF4, Schizophrenia, and Pitt-Hopkins Syndrome. Schizophrenia Bulletin 36(3), pp. 443-447. (10.1093/schbul/sbq035)
• Liu, Y. et al. 2010. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder [Letter]. Molecular Psychiatry 16(1), pp. 2-4. (10.1038/mp.2009.107)
• Craddock, N. J. and Owen, M. J. 2010. Authors' reply:. British Journal of Psychiatry 196(6), pp. 495-496. (10.1192/bjp.196.6.495a)
• Craddock, N. J. and Owen, M. J. 2010. Molecular genetics and the relationship between epilepsy and psychosis [Letter]. British Journal of Psychiatry 197(1), pp. 75-76. (10.1192/bjp.197.1.75a)
• Craddock, N. J. and Owen, M. J. 2010. Data and clinical utility should be the drivers of changes to psychiatric classification [Letter]. British Journal of Psychiatry 197(2), pp. 158. (10.1192/bjp.197.2.158)
• Lewis, C. M. et al. 2010. Genome-wide association study of major recurrent depression in the U.K. population. American Journal of Psychiatry 167(8), pp. 949-957. (10.1176/appi.ajp.2010.09091380)
• Cruchaga, C. et al. 2010. SNPS associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease. PLoS Genetics 6(9), article number: e1001101. (10.1371/journal.pgen.1001101)
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2009

• Fowler, T. A. et al. 2009. Psychopathy trait scores in adolescents with childhood ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity. Psychiatric Genetics 19(6), pp. 312-319. (10.1097/YPG.0b013e3283328df4)
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• Raychaudhuri, S. et al. 2009. Identifying relationships among genomic disease regions: Predicting genes at pathogenic SNP associations and rare deletions. Plos Genetics 5(6), pp. -. (10.1371/journal.pgen.1000534)
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• Harold, D. et al. 2009. Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease [Corrigendum]. Nature Genetics 41(10), pp. 1156. (10.1038/ng1009-1156d)
• Purcell, S. M. et al. 2009. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460(7256), pp. 748-752. (10.1038/nature08185)
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• Owen, M. J. and Craddock, N. J. 2009. Diagnosis of functional psychoses: time to face the future [Comment]. The Lancet 373(9659), pp. 190-191. (10.1016/S0140-6736(09)60053-2)
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• Langley, K. et al. 2009. Molecular genetic contribution to the developmental course of attention-deficit hyperactivity disorder. European Child & Adolescent Psychiatry 18(1), pp. 26-32. (10.1007/s00787-008-0698-4)
• Morgan, A. R. et al. 2009. Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B(1), pp. 61-64. (10.1002/ajmg.b.30768)
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• Carroll, L. S., Kendall, K., O'Donovan, M. C., Owen, M. J. and Williams, N. M. 2009. Evidence that putative ADHD low risk alleles atSNAP25may increase the risk of schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B(7), pp. 893-899. (10.1002/ajmg.b.30915)
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• O'Donovan, M. C. and Owen, M. J. 2009. Genetics and the brain: many pathways to enlightenment [Editorial]. Human Genetics 126(1), pp. 1-2. (10.1007/s00439-009-0705-y)
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• Smith, D. J., Owen, M. J. and Craddock, N. J. 2009. Bipolar disorder and unipolar depression: what is the genetic relationship?. In: Pariante, C. M. et al. eds. Understanding Depression: a Translational Approach. Oxford: Oxford University Press, pp. 67-76.
• Owen, M. J., Williams, H. J. and O'Donovan, M. C. 2009. Schizophrenia genetics: advancing on two fronts. Current Opinion in Genetics & Development 19(3), pp. 266-270. (10.1016/j.gde.2009.02.008)
• Gerrish, A., Williams, H. J., Escott-Price, V., Owen, M. J., O'Donovan, M. C. and Williams, N. M. 2009. An examination of MUTED as a schizophrenia susceptibility gene [Letter]. Schizophrenia Research 107(1), pp. 110-111. (10.1016/j.schres.2008.08.011)
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• Yosifova, A. et al. 2009. Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. Journal of Affective Disorders 117(1-2), pp. 87-97. (10.1016/j.jad.2008.12.021)
• Cohen-Woods, S. et al. 2009. Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder. Human Molecular Genetics 18(8), pp. 1504-1509. (10.1093/hmg/ddp051)
• Kirov, G. and Owen, M. J. 2009. Genetics of schizophrenia. In: Sadock, B. J., Sadock, V. A. and Ruiz, P. eds. Kaplan and Sadock’s Comprehensive Textbook of Psychiatry. 9th ed.., Vol. 1. Philadelphia: Lippincott Williams and Wilkins, pp. 1462-1474.
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• Craddock, N. J., O'Donovan, M. C. and Owen, M. J. 2009. Psychosis genetics: modeling the relationship between Schizophrenia, Bipolar Disorder, and Mixed (or "Schizoaffective") Psychoses. Schizophrenia Bulletin 35(3), pp. 482-490. (10.1093/schbul/sbp020)
• Kirov, G., Rujescu, D., Ingason, A., Collier, D. A., O'Donovan, M. C. and Owen, M. J. 2009. Neurexin 1 (NRXN1) deletions in Schizophrenia. Schizophrenia Bulletin 35(5), pp. 851-854. (10.1093/schbul/sbp079)
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• Samaan, Z., Farmer, A., Craddock, N. J., Jones, L., Korszun, A., Owen, M. J. and McGuffin, P. 2009. Migraine in recurrent depression: case-control study (Paper). British Journal of Psychiatry 194(4), pp. 350-354. (10.1192/bjp.bp.108.054049)
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2008

• Barton, A. et al. 2008. Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Nature Genetics 40(10), pp. 1156-1159. (10.1038/ng.218)
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• Richards, A. L., Holmans, P. A., O'Donovan, M. C., Owen, M. J. and Jones, L. 2008. A comparison of four clustering methods for brain expression microarray data. BMC Bioinformatics 9, article number: 490. (10.1186/1471-2105-9-490)

2007

• Nejentsev, S. et al. 2007. Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature 450(7171), pp. 887-892. (10.1038/nature06406)
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• Zammit, S., Spurlock, G., Williams, H., Norton, N., Williams, N. M., O'Donovan, M. C. and Owen, M. J. 2007. Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use. British Journal of Psychiatry 191(5), pp. 402-407. (10.1192/bjp.bp.107.036129)
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• Nicholas, B., Rudrasingham, V., Nash, S., Kirov, G., Owen, M. J. and Wimpory, D. C. 2007. Association of Per1 and Npas2 with autistic disorder: support for the clock genes/social timing hypothesis. Molecular Psychiatry 12(6), pp. 581-592. (10.1038/sj.mp.4001953)
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• Gaughran, F., Blizard, R., Mohan, R., Zammit, S. and Owen, M. J. 2007. Birth order and the severity of illness in schizophrenia. Psychiatry Research 150(2), pp. 205-210. (10.1016/j.psychres.2006.05.012)
• Le Hellard, S. et al. 2007. Haplotype Analysis and a Novel Allele-Sharing Method Refines a Chromosome 4p Locus Linked to Bipolar Affective Disorder. Biological psychiatry 61(6), pp. 797-805. (10.1016/j.biopsych.2006.06.029)
• O'Donovan, M. C. et al. 2007. Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia [Conference Abstract]. Schizophrenia bulletin 33(2), pp. 311-312. (10.1093/schbul/sbm004)
• Grupe, A. et al. 2007. Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Human Molecular Genetics 16(8), pp. 865-873. (10.1093/hmg/ddm031)
• Gunnell, D. et al. 2007. IGF1, growth pathway polymorphisms and schizophrenia: A pooling study. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 144B(1), pp. 117-120. (10.1002/ajmg.b.30396)
• Hamilton, G., Proitsi, P., Williams, J., O'Donovan, M. C., Owen, M. J., Powell, J. and Lovestone, S. 2007. Complement factor H Y402H polymorphism is not associated with late-onset Alzheimer's disease. Neuromolecular Medicine 9(4), pp. 331-334. (10.1007/s12017-007-8013-y)
• Burton, P. R. et al. 2007. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nature Genetics 39(11), pp. 1329-1337. (10.1038/ng.2007.17)
• Craddock, N. J., O'Donovan, M. C. and Owen, M. J. 2007. Symptom dimensions and the Kraepelinian dichotomy. British Journal of Psychiatry 190(4), pp. 361. (10.1192/bjp.190.4.361)
• Craddock, N. J., O'Donovan, M. C. and Owen, M. J. 2007. Phenotypic and genetic complexity of psychosis Invited commentary on .. Schizophrenia: a common disease caused by multiple rare alleles. British Journal of Psychiatry 190(3), pp. 200-203. (10.1192/bjp.bp.106.033761)
• Rice, F. et al. 2007. Agreement between maternal report and antenatal records for a range of pre and peri-natal factors: The influence of maternal and child characteristics. Early Human Development 83(8), pp. 497-504. (10.1016/j.earlhumdev.2006.09.015)
• Morgan, A. et al. 2007. Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B(6), pp. 727-731. (10.1002/ajmg.b.30670)
• Talkowski, M. E. et al. 2007. A network of dopaminergic gene variations implicated as risk factors for schizophrenia. Human Molecular Genetics 17(5), pp. 747-758. (10.1093/hmg/ddm347)
• Thapar, A. et al. 2007. Promoting Measured Genes and Measured Environments: On the Importance of Careful Statistical Analyses and Biological Relevance—Reply [Letter]. Archives of General Psychiatry 64(3), pp. 378-379. (10.1001/archpsyc.64.3.378-b)

2006

• van Amelsvoort, T. et al. 2006. Processing facial emotions in adults with velo-cardio-facial syndrome: functional magnetic resonance imaging. British Journal of Psychiatry 189(6), pp. 560-561. (10.1192/bjp.bp.105.019876)
• Harold, D. et al. 2006. Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia. Molecular Psychiatry 11(12), pp. 1085-91. (10.1038/sj.mp.4001904)
• O'Donovan, M. et al. 2006. Genetic dissection of behavioural abnormalities in mouse models of DiGeorge/velocardiofacial syndrome. Journal of intellectual disability research 50(11), pp. 781 -781.
• Glaser, B. et al. 2006. Analysis of ProDH, COMT and ZDHHC8 risk variants does not support individual or interactive effects on schizophrenia susceptibility. Schizophrenia Research 87(1-3), pp. 21. (10.1016/j.schres.2006.05.024)
• Zammit, S. et al. 2006. Phenotypic variation between parent-offspring trios and non-trios in genetic studies of schizophrenia. Journal of Psychiatric Research 40(7), pp. 622-626. (10.1016/j.jpsychires.2005.05.006)
• Bray, N. J. et al. 2006. Cis- and trans-acting loci influence expression of DTNBP1, a susceptibility gene for schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 141B(7), pp. 723-724.
• Hollingworth, P. et al. 2006. Four Components Describe Behavioral Symptoms in 1,120 Individuals with Late-Onset Alzheimer's Disease. Journal of the American Geriatrics Society 54(9), pp. 1348-1354. (10.1111/j.1532-5415.2006.00854.x)
• Li, Y. et al. 2006. DAPK1 variants are associated with Alzheimer's disease and allele-specific expression. Human Molecular Genetics 15(17), pp. 2560-2568. (10.1093/hmg/ddl178)
• Georgieva, L. et al. 2006. Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia. Proceedings of the National Academy of Sciences of the United States of America (PNAS) ISSN 1091-6490 103(33), pp. 12469-12474. (10.1073/pnas.0603029103)
• Owen, M. J. 2006. Genes and behavior: nature-nurture interplay explained. British Journal of Psychiatry 189(2), pp. 192-193. (10.1192/bjp.189.2.192)
• Thapar, A., Langley, K., O'Donovan, M. C. and Owen, M. J. 2006. Refining the attention deficit hyperactivity disorder phenotype for molecular genetic studies. Molecular Psychiatry 11(8), pp. 714-20. (10.1038/sj.mp.4001831)
• Li, D., Owen, M. J., Sham, P. C. and Lin, H. 2006. Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Human Molecular Genetics 15(14), pp. 2276-2284. (10.1093/hmg/ddl152)
• Talkowski, M. E. et al. 2006. Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples. Biological psychiatry 60(2), pp. 152-162. (10.1016/j.biopsych.2006.02.015)
• Rees, M. I. et al. 2006. Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease. Nature genetics 38(7), pp. 801-806. (10.1038/ng1814)
• Hamilton, G. et al. 2006. Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease. Neuroscience Letters 401(1-2), pp. 77-80. (10.1016/j.neulet.2006.03.021)
• Paylor, R. et al. 2006. Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: Implications for 22q11 deletion syndrome. Proceedings of the National Academy of Sciences of the United States of America 103(20), pp. 7729-7734. (10.1073/pnas.0600206103)
• Williams, N. M. et al. 2006. Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder. Archives of General Psychiatry 63(4), pp. 366-373. (10.1001/archpsyc.63.4.366)
• Escott-Price, V., Craddock, N. J., Holmans, P. A., Owen, M. J. and O'Donovan, M. C. 2006. Effects of differential genotyping error rate on the Type 1 error probability of case-control studies. Human heredity 61(1), pp. 55-64. (10.1159/000092553)
• Norton, N., Williams, H. J. and Owen, M. J. 2006. An update on the genetics of schizophrenia. Current Opinion in Psychiatry 19(2), pp. 158-164. (10.1097/01.yco.0000214341.52249.59)
• Kirov, G., Nikolov, I., Georgieva, L., Escott-Price, V., Owen, M. J. and O'Donovan, M. C. 2006. Pooled DNA genotyping on Affymetrix SNP genotyping arrays. BMC Genomics 7(1), pp. 27-37. (10.1186/1471-2164-7-27)
• Harold, D. et al. 2006. A single nucleotide polymorphism in CHAT influences response to acetylcholinesterase inhibitors in Alzheimer's disease. Pharmacogenetics and genomics 16(2), pp. 75-77.
• Williams, N. M., O'Donovan, M. C. and Owen, M. J. 2006. Chromosome 22 deletion syndrome and schizophrenia. International Review of Neurobiology 73, pp. 1-27. (10.1016/S0074-7742(06)73001-X)
• Smemo, S. et al. 2006. Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease. Annals of Neurology 59(1), pp. 21-26. (10.1002/ana.20673)
• Grupe, A. et al. 2006. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. The American Journal of Human Genetics 78(1), pp. 78-88.
• Peirce, T. R. et al. 2006. Convergent evidence for 2',3'-cyclic nucleotide 3'-phosphodiesterase as a possible susceptibility gene for schizophrenia. Archives of general psychiatry 63(1), pp. 18-24. (10.1001/archpsyc.63.1.18)
• Peirce, T. et al. 2006. Convergent evidence for 2 ',3 '-cyclic nucleotide 3 '-phosphodiesterase as a possible susceptibility gene for schizophrenia. Archives of General Psychiatry 63(1), pp. 18-24.
• Norton, N. et al. 2006. Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 141B(1), pp. 96-101. (10.1002/ajmg.b.30236)
• Lambert, D. et al. 2006. Stage 2 of the Wellcome Trust UK–Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16–q21, 4q12–q21, 9p21, 10p14–p12 and 18q22 - Corrigendum. Molecular Psychiatry 11(12), pp. 1140-1143. (10.1038/sj.mp.4001917)
• Green, E. K. et al. 2006. Evidence that a DISC1 frame-shift deletion associated with psychosis in a single family may not be a pathogenic mutation. Molecular Psychiatry 11(9), pp. 798-799. (10.1038/sj.mp.4001853)
• Hamshere, M. L. et al. 2006. Genome wide significant linkage in schizophrenia conditioning on occurrence of depressive episodes. Journal of Medical Genetics 43(7), pp. 563-567. (10.1136/jmg.2005.035345)
• Craddock, N. J., Owen, M. J. and O'Donovan, M. C. 2006. The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons. Molecular Psychiatry 11(5), pp. 446-458. (10.1038/sj.mp.4001808)
• Blair, I. P. et al. 2006. Positional cloning, association analysis and expression studies provide convergent evidence that the cadherin gene FAT contains a bipolar disorder susceptibility allele. Molecular Psychiatry 11(4), pp. 372-383. (10.1038/sj.mp.4001784)
• Green, E. K. et al. 2006. Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK. British Journal of Psychiatry 188(1), pp. 21-25. (10.1192/bjp.bp.105.009969)

2005

• Langley, K. et al. 2005. No support for association between the dopamine transporter (DAT1) gene and ADHD. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 139B(1), pp. 7-10. (10.1002/ajmg.b.30206)
• Craddock, N. J. and Owen, M. J. 2005. Kraepelinian dichotomy - Author's reply. British Journal of Psychiatry 187, pp. 485-486.
• Thapar, A. et al. 2005. Catechol O-methyltransferase gene variant and birth weight predict early-onset antisocial behavior in children with attention-deficit/hyperactivity disorder. Archives of General Psychiatry 62(11), pp. 1275-1278. (10.1001/archpsyc.62.11.1275)
• Thapar, A., O'Donovan, M. C. and Owen, M. J. 2005. The genetics of attention deficit hyperactivity disorder. Human Molecular Genetics 14(2), pp. 275-282. (10.1093/hmg/ddi263)
• Williams, N. M., O'Donovan, M. C. and Owen, M. J. 2005. Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia?. Schizophrenia Bulletin 31(4), pp. 800-805. (10.1093/schbul/sbi061)
• Hamshere, M. L. et al. 2005. Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13. Archives of general psychiatry 62(10), pp. 1081-1088. (10.1001/archpsyc.62.10.1081)
• Li, Y. et al. 2005. The BDNF Val66Met polymorphism is not associated with late onset Alzheimer's disease in three case-control samples. Molecular Psychiatry 10(9), pp. 809-810. (10.1038/sj.mp.4001702)
• Williams, H. J. et al. 2005. No association between schizophrenia and polymorphisms in COMT in two large samples. American Journal of Psychiatry 162(9), pp. 1736-1738. (10.1176/appi.ajp.162.9.1736)
• Ahuja, A., Thapar, A. and Owen, M. J. 2005. Genetics of mental retardation. Indian Journal of Medical Sciences 59(9), pp. 407-417. (10.4103/0019-5359.16820)
• Kirov, G., Tredget, J., John, R., Owen, M. J. and Lazarus, J. H. 2005. A cross-sectional and a prospective study of thyroid disorders in lithium-treated patients. Journal of affective disorders 87(2-3), pp. 313-317. (10.1016/j.jad.2005.03.010)
• Glaser, B. et al. 2005. No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples. Biological psychiatry 58(1), pp. 78-80.
• Kirov, G., O'Donovan, M. C. and Owen, M. J. 2005. Finding schizophrenia genes. The Journal of Clinical Investigation 115(6), pp. 1440-1448. (10.1172/JCI24759)
• Turic, D. et al. 2005. A family based study implicates solute carrier family 1-member 3 (SLC1A3) gene in attention-deficit/hyperactivity disorder. Biological psychiatry 57(11), pp. 1461-1466. (10.1016/j.biopsych.2005.03.025)
• Green, E. K. et al. 2005. Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder. Archives of general psychiatry 62(6), pp. 642-648. (10.1001/archpsyc.62.6.642)
• Norton, N. et al. 2005. No evidence for association between polymorphisms in GRM3 and schizophrenia. BMC Psychiatry 5, article number: 23. (10.1186/1471-244X-5-23)
• Holmans, P. A. et al. 2005. Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 135B(1), pp. 24-32. (10.1002/ajmg.b.30114)
• Lambert, D. et al. 2005. Stage 2 of the Wellcome Trust UK-Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16-q21, 4q12-q21, 9p21, 10p14-p12 and 18q22. Molecular psychiatry 10(9), pp. 831-841. (10.1038/sj.mp.4001684)
• Bray, N. J., Preece, A. C., Williams, N. M., Escott-Price, V., Buckland, P. R., Owen, M. J. and O'Donovan, M. C. 2005. Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression. Human Molecular Genetics 14(14), pp. 1947-1954. (10.1093/hmg/ddi199)
• Cope, N. A. et al. 2005. Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia. American Journal of Human Genetics 76(4), pp. 581-591. (10.1086/429131)
• Escott-Price, V., Norton, N., Williams, N. M., Holmans, P. A., Owen, M. J. and O'Donovan, M. C. 2005. Streamlined analysis of pooled genotype data in SNP-based association studies. Genetic Epidemiology 28(3), pp. 273-282. (10.1002/gepi.20062)
• Li, Y. et al. 2005. Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease. Human Mutation 25(3), pp. 270-277. (10.1002/humu.20138)
• Owen, M. J. 2005. Linkage studies in schizophrenia: New findings promise new insights. European Psychiatry 20(1), pp. S36-S36.
• Cope, N. A. et al. 2005. No support for association between dyslexia susceptibility 1 candidate 1 and developmental dyslexia. Molecular Psychiatry 10(3), pp. 237-238. (10.1038/sj.mp.4001596)
• Turic, D., Williams, H., Langley, K., Owen, M. J., Thapar, A. and O'Donovan, M. C. 2005. A family based study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD).. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 133B(1), pp. 64-67. (10.1002/ajmg.b.30123)
• Owen, M. J., O'Donovan, M. C. and Harrison, P. J. 2005. Schizophrenia: a genetic disorder of the synapse?. British Medical Journal (BMJ) 330(7484), pp. 158-159. (10.1136/bmj.330.7484.158)
• Glaser, B., Kirov, G., Green, E., Craddock, N. J. and Owen, M. J. 2005. Linkage disequilibrium mapping of bipolar affective disorder at 12q23-q24 provides evidence for association at CUX2 and FLJ32356. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 132B(1), pp. 38-45. (10.1002/ajmg.b.30081)
• Owen, M. J. 2005. Genomic approaches to schizophrenia. Clinical Therapeutics 27(A), pp. S2-S7.
• Dimitrova, A., Milanova, V., Krastev, S., Nikolov, I., Toncheva, D., Owen, M. J. and Kirov, G. 2005. Association study of myo-inositol monophosphatase 2 (IMPA2) polymorphisms with bipolar affective disorder and response to lithium treatment.. The Pharmacogenomics Journal 5(1), pp. 35-41. (10.1038/sj.tpj.6500273)
• Norton, N. and Owen, M. J. 2005. HTR2A: association and expression studies in neuropsychiatric genetics. Annals of Medicine 37(2), pp. 121-129.
• Craddock, N. J., O'Donovan, M. C. and Owen, M. J. 2005. Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophrenia Bulletin 32(1), pp. 9-16. (10.1093/schbul/sbj033)
• McGuffin, P. et al. 2005. Whole genome linkage scan of recurrent depressive disorder from the depression network study. Human Molecular Genetics 14(22), pp. 3337-3345. (10.1093/hmg/ddi363)
• Kent, L. et al. 2005. Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD. Molecular Psychiatry 10(10), pp. 939-943. (10.1038/sj.mp.4001696)
• Glaser, B., Kirov, G., Bray, N. J., Green, E., O'Donovan, M. C., Craddock, N. J. and Owen, M. J. 2005. Identification of a potential Bipolar risk haplotype in the gene encoding the winged-helix transcription factor RFX4. Molecular Psychiatry 10(10), pp. 920-927. (10.1038/sj.mp.4001689)
• Owen, M. J., Craddock, N. J. and O'Donovan, M. C. 2005. Schizophrenia: genes at last?. Trends in Genetics 21(9), pp. 518-525. (10.1016/j.tig.2005.06.011)
• Raybould, R. et al. 2005. Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1). Biological psychiatry 57(7), pp. 696-701. (10.1016/j.biopsych.2005.01.018)
• Craddock, N. J., O'Donovan, M. C. and Owen, M. J. 2005. The genetics of schizophrenia and bipolar disorder: dissecting psychosis. Journal of Medical Genetics 42(3), pp. 193-204. (10.1136/jmg.2005.030718)
• Green, E. et al. 2005. Localization of bipolar susceptibility locus by molecular genetic analysis of the chromosome 12q23-q24 region in two pedigrees with bipolar disorder and Darier's disease. American Journal of Psychiatry 162(1), pp. 35-42. (10.1176/appi.ajp.162.1.35)

2004

• Farmer, A. et al. 2004. The Depression Network (DeNT) Study: methodology and sociodemographic characteristics of the first 470 affected sibling pairs from a large multi-site linkage genetic study. BMC Psychiatry 4, article number: 42. (10.1186/1471-244X-4-42)
• Jones, G. and Owen, M. J. 2004. Genetics: The implications for forensic psychiatry. Journal of Forensic Psychiatry & Psychology 15(4), pp. 696-704. (10.1080/14789940410001729509)
• Li, Y. et al. 2004. Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family. Proceedings of the National Academy of Sciences 101(44), pp. 15688-15693. (10.1073/pnas.0403535101)
• van Amelsvoort, T. et al. 2004. Brain anatomy in adults with velocardiofacial syndrome with and without schizophrenia: preliminary results of a structural magnetic resonance imaging study. Archives of General Psychiatry 61(11), pp. 1085-1096. (10.1001/archpsyc.61.11.1085)
• van Amelsvoort, T., Henry, J., Morris, R., Owen, M. J., Linszen, D., Murphy, K. and Murphy, D. 2004. Cognitive deficits associated with schizophrenia in velo-cardio-facial syndrome. Schizophrenia Research 70(2-3), pp. 223-232. (10.1016/j.schres.2003.10.004)
• Fowler, T. A. et al. 2004. Early onset antisocial behaviour in children with ADHD is associated with a functional variant in the catechol-O-methyltransferase (COMT) gene [Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B(1), pp. 98-98. (10.1002/ajmg.b.30101)
• Bray, N. J. et al. 2004. Allelic variation in the expression of neuropsychiatric candidate genes [Conference Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B(1), pp. 25-25.
• Peirce, T. R. et al. 2004. Convergent functional genomics, association and linkage analysis suggests 2 ',3 '-cyclic nucleotide 3 '-phosphodiesterase (CNP) as a potential susceptibility gene for schizophrenia [Conference Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B(1), pp. 81-81. (10.1002/ajmg.b.30101)
• Farbrother, J. E., Kirov, G., Owen, M. J. and Guggenheim, J. A. 2004. Family aggregation of high myopia: estimation of the sibling recurrence risk ratio. Investigative Ophthalmology and Visual Science 45(9), pp. 2873-2878. (10.1167/iovs.03-1155)
• Farbrother, J. E., Kirov, G., Owen, M. J., Pong-Wong, R., Haley, C. S. and Guggenheim, J. A. 2004. Linkage analysis of the genetic loci for high myopia on chromosomes 18p, 12q and 17q in 51 UK families. Investigative Ophthalmology and Visual Science 45(9), pp. 2879-2885. (10.1167/iovs.03-1156)
• Bray, N. J., Jehu, L., Escott-Price, V., Buckland, P. R., Williams, J., Owen, M. J. and O'Donovan, M. C. 2004. Allelic expression of APOE in brain [Conference Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B(1), pp. 61-61.
• Norton, N. et al. 2004. Interaction between neuregulin 1 and its receptor ERBB4 increases susceptibility to schizophrenia [Conference Abstract]. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 130B(1), pp. 18-18.
• Li, Y. et al. 2004. Association of ABCA1 with late-onset Alzheimer?s disease is not observed in a case-control study. Neuroscience Letters 366(3), pp. 268-271. (10.1016/j.neulet.2004.05.047)
• Mowry, B. J. et al. 2004. Multicenter linkage study of schizophrenia loci on chromosome 22q. Molecular Psychiatry 9(8), pp. 784-795. (10.1038/sj.mp.4001481)
• Morris, D. et al. 2004. Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1-15.3 region associated with reading disability. American Journal Of Medical Genetics Part A 129B(1), pp. 97-103. (10.1002/ajmg.b.30033)
• Zammit, S. et al. 2004. Polymorphisms in the MAOA, MAOB, and COMT genes and aggressive behavior in schizophrenia. American Journal of Medical Genetics 128B(1), pp. 19-20. (10.1002/ajmg.b.30021)
• Bray, N. J., Jehu, L., Escott-Price, V., Buckland, P. R., Owen, M. J., Williams, J. and O'Donovan, M. C. 2004. P4-101 Allelic expression of APOE in brain [Conference Abstract]. Neurobiology of Aging 25, pp. S503-S503. (10.1016/S0197-4580(04)81659-2)
• Harvey, K. et al. 2004. The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering. Journal of neuroscience 24(25), pp. 5816-5826. (10.1523/JNEUROSCI.1184-04.2004)
• Reid, S. J. et al. 2004. TBP, a polyglutamine tract containing protein, accumulates in Alzheimer's disease. Molecular Brain Research 125(1-2), pp. 120-128. (10.1016/j.molbrainres.2004.03.018)
• Mills, S. et al. 2004. No evidence of association between Catechol-O-Methyltransferase (COMT) Val(158)Met genotype and performance on neuropsychological tasks in children with ADHD: A case-control study. BMC Psychiatry 4, pp. 15-15. (10.1186/1471-244X-4-15)
• Plomin, R. et al. 2004. A functional polymorphism in the succinate-semialdehyde dehydrogenase (aldehyde dehydrogenase 5 family, member A1) gene is associated with cognitive ability. Molecular Psychiatry 9(6), pp. 582-586. (10.1038/sj.mp.4001441)
• Zammit, S., Allebeck, P., Dalman, C., Lundberg, I., Hemmingson, T., Owen, M. J. and Lewis, G. 2004. Parental age difference and schizophrenia - Reply. British Journal of Psychiatry 184, pp. 540-541.
• Williams, N. M. and Owen, M. J. 2004. Genetic abnormalities of chromosome 22 and the development of psychosis. Current Psychiatry Reports 6(3), pp. 176-182. (10.1007/s11920-004-0062-4)
• Kirov, G. et al. 2004. Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria. Biological psychiatry 55(10), pp. 971-975. (10.1016/j.biopsych.2004.01.025)
• Turic, D., Langley, K., Kirov, G., Owen, M. J., Thapar, A. and O'Donovan, M. C. 2004. Direct analysis of the genes encoding G proteins G alpha T2, G alpha o, G alpha Z in ADHD. American Journal of Medical Genetics 127B(1), pp. 68-72. (10.1002/ajmg.b.20173)
• Korszun, A. et al. 2004. Familiarity of symptom dimensions in depression. Archives of General Psychiatry 61(5), pp. 468-474. (10.1001/archpsyc.61.5.468)
• Owen, M. J., Williams, N. M. and O'Donovan, M. C. 2004. Dysbindin-1 and schizophrenia: from genetics to neuropathology. The Journal of Clinical Investigation 113(9), pp. 1255-1257. (10.1172/JCI200421470)
• Fekadu, A., Shibre, T., Alem, A., Kebede, D., Kebreab, S., Negash, A. and Owen, M. J. 2004. Bipolar disorder among an isolated island community in Ethiopia. Journal of affective disorders 80(1), pp. 1-10. (10.1016/S0165-0327(02)00345-2)
• Murphy, K., Williams, H., Owen, M. J. and O'Donovan, M. C. 2004. What can velo-cardio-facial syndrome tell us about the genetics of schizophrenia?. European Psychiatry 19(Supp1), pp. 96S-96S.
• Williams, N. M. et al. 2004. Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1). Archives of General Psychiatry 61(4), pp. 336-344. (10.1001/archpsyc.61.4.336)
• Cook, L. J. et al. 2004. Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease. Neuroscience Letters 358(2), pp. 142-146. (10.1016/j.neulet.2004.01.016)
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• Owen, M. J., Williams, N. M. and O'Donovan, M. C. 2004. The molecular genetics of schizophrenia: new findings promise new insights. Molecular Psychiatry 9(1), pp. 14-27. (10.1038/sj.mp.4001444)
• Myers, A. J. et al. 2004. Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD. American Journal of Medical Genetics 124B(1), pp. 29-37. (10.1002/ajmg.b.20036)
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• Busby, V. et al. 2004. Alpha-T-Catenin Is Expressed in Human Brain and Interacts With the Wnt Signaling Pathway But Is Not Responsible for Linkage to Chromosome 10 in Alzheimer's Disease. Neuromolecular Medicine 5(2), pp. 133-146. (10.1385/NMM:5:2:133)
• Bray, N. J., Buckland, P. R., Hall, H., Owen, M. J. and O'Donovan, M. C. 2004. The serotonin-2A receptor gene locus does not contain common polymorphism affecting mRNA levels in adult brain. Molecular Psychiatry 9(1), pp. 109-114. (10.1038/sj.mp.4001366)
• Bray, N. J. et al. 2004. Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes. Human Molecular Genetics 13(22), pp. 2885-2892. (10.1093/hmg/ddh299)
• Cichon, S. et al. 2004. Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin. Nature Genetics 36(8), pp. 783-784. (10.1038/ng0804-783)
• Turic, D. et al. 2004. Follow-up of genetic linkage findings on chromosome 16p13: evidence of association of N-methyl-D aspartate glutamate receptor 2A gene polymorphism with ADHD. Molecular Psychiatry 9(2), pp. 169-173. (10.1038/sj.mp.4001387)

2003

• Williams, N. M. et al. 2003. A systematic genomewide linkage study in 353 sib pairs with schizophrenia. The American journal of human genetics 73(6), pp. 1355-1367. (10.1086/380206)
• Marchbanks, R., Ryan, M., Day, I., Owen, M. J., McGuffin, P. and Whatley, S. 2003. A mitochondrial DNA sequence variant associated with schizophrenia and oxidative stress. Schizophrenia Research 65(1), pp. 33-38. (10.1016/S0920-9964(03)00011-2)
• Ivanov, D. et al. 2003. Chromosome 22q11 deletions, velo-cardio-facial syndrome and early-onset psychosis: Molecular genetic study. The British Journal of Psychiatry 183(5), pp. 409-413. (10.1192/bjp.183.5.409)
• Zammit, S., Allebeck, P., Dalman, C., Lundberg, I., Hemmingson, T., Owen, M. J. and Lewis, G. 2003. Paternal age and risk for schizophrenia. British Journal of Psychiatry 183(5), pp. 405-408. (10.1192/bjp.183.5.405)
• Thapar, A., Langley, K., Marshall, L., van den Bree, M. B., Thomas, H. V., Owen, M. J. and O'Donovan, M. C. 2003. ADHD children with and without the dopamine D4 receptor 7-repeat allele: Evidence of differences in performance on neuropsychological tests. Behavior Genetics 33(6), pp. 721-721.
• O'Donovan, M. C., Williams, N. M. and Owen, M. J. 2003. Recent advances in the genetics of schizophrenia. Human Molecular Genetics 12(suppl), pp. R125-R133. (10.1093/hmg/ddg302)
• Kirov, G. et al. 2003. Variation in the protocadherin - A gene cluster?. Genomics 82(4), pp. 433-440. (10.1016/S0888-7543(03)00167-8)
• Payton, A. et al. 2003. No evidence of association between HLA-DRB1 and attention deficit hyperactivity disorder.. Psychiatric Genetics 13(3), pp. 183-185.
• Harold, D. et al. 2003. Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease. Human Genetics 113(3), pp. 258-267. (10.1007/s00439-003-0960-2)
• Rees, M. I. et al. 2003. Isoform heterogeneity of the human gephyrin gene (GPHN), binding domains to the glycine receptor, and mutation analysis in hyperekplexia. Journal of Biological Chemistry 278(27), pp. 24688-24696. (10.1074/jbc.M301070200)
• Norton, N. et al. 2003. Mutation screening of the Homer gene family and association analysis in schizophrenia. American Journal of Medical Genetics 120B(1), pp. 18-21. (10.1002/ajmg.b.20032)
• Williams, H. et al. 2003. Detailed analysis of PRODH and PsPRODH reveals no association with schizophrenia. American Journal of Medical Genetics 120B(1), pp. 42-46. (10.1002/ajmg.b.20049)
• Williams, H. J. et al. 2003. Association between PRODH and schizophrenia is not confirmed. Molecular Psychiatry 8(7), pp. 644-645. (10.1038/sj.mp.4001276)
• Lewis, C. M. et al. 2003. Genome scan meta-analysis of schizophrenia and bipolar disorder, Part II: schizophrenia. American Journal of Human Genetics 73(1), pp. 34-48. (10.1086/376549)
• Bray, N. B., Buckland, P. R., Owen, M. J. and O'Donovan, M. C. 2003. Cis-acting variation in the expression of a high proportion of genes in human brain. Human Genetics 113(2), pp. 149-153. (10.1007/s00439-003-0956-y)
• Bray, N. J., Buckland, P. R., Williams, N. M., Williams, H. J., Norton, N., Owen, M. J. and O'Donovan, M. C. 2003. A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain. The American Journal of Human Genetics 73(1), pp. 152-161. (10.1086/376578)
• Langley, K. et al. 2003. No evidence of association of two 5HT transporter gene polymorphisms and attention deficit hyperactivity disorder. Psychiatric Genetics 13(2), pp. 107-110. (10.1097/01.ypg.0000056177.32550.a5)
• Edwards, D., Burnard, P., Owen, M. J., Hannigan, B., Fothergill, A. and Coyle, D. 2003. A systematic review of the effectiveness of stress-management interventions for mental health professionals. Journal of Psychiatric and Mental Health Nursing 10(3), pp. 370-371. (10.1046/j.1365-2850.2003.00606.x)
• Reid, S. J. et al. 2003. Molecular investigation of TBP allele length:. Neurobiology of Disease 13(1), pp. 37-45. (10.1016/S0969-9961(03)00014-7)
• Georgieva, L., Nikolov, I., Poriazova, N., Jones, G., Toncheva, D., Kirov, G. and Owen, M. J. 2003. Genetic variation in the seven-pass transmembrane cadherin CELSR1. Psychiatric Genetics 13(2), pp. 103-106. (10.1097/01.ypg.0000057486.14812.03)
• Jönsson, E. G. et al. 2003. Association between a promoter variant in the monoamine oxidase A gene and schizophrenia. Schizophrenia Research 61(1), pp. 31-37. (10.1016/S0920-9964(02)00224-4)
• Williams, N. M. et al. 2003. Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia. Molecular Psychiatry 8(5), pp. 485-487. (10.1038/sj.mp.4001348)
• Kirov, G. et al. 2003. Association analysis of the HOPA12bp polymorphism in schizophrenia and manic depressive illness. American Journal of Medical Genetics 118B(1), pp. 16-19. (10.1002/ajmg.b.10065)
• Jordan, N., Williams, N. M., Gregory, J. W., Evans, C., Owen, M. J. and Ludgate, M. E. 2003. The W546X mutation of the thyrotropin receptor gene: potential major contributor to thyroid dysfunction in a Caucasian population. Journal of Clinical Endocrinology & Metabolism 88(3), pp. 1002-5. (10.1210/jc.2002-021301)
• Harrison, P. J. and Owen, M. J. 2003. Genes for schizophrenia? Recent findings and their pathophysiological implications. The Lancet 361(9355), pp. 417-419. (10.1016/S0140-6736(03)12379-3)
• Rice, F., Abraham, R., Rudrasingham, V., Owen, M. J. and Williams, J. 2003. Memory for new information as a cognitive marker of liability to Alzheimer's disease in a high risk group: a research note. International Journal of Geriatric Psychiatry 18(2), pp. 155-160. (10.1002/gps.808)
• Turic, D. et al. 2003. Linkage disequilibrium mapping provides further evidence of a gene for reading disability on chromosome 6p21.3-22. Molecular Psychiatry 8(2), pp. 176-185. (10.1038/sj.mp.4001216)
• Lawson, D. C. et al. 2003. Association analysis of monoamine oxidase a and attention deficit hyperactivity disorder. American Journal of Medical Genetics 116B(1), pp. 84-89. (10.1002/ajmg.b.10002)
• van den Bree, M. B. and Owen, M. J. 2003. The future of psychiatric genetics. Annals of Medicine 35(2), pp. 122-134. (10.1080/07853890310010023)
• Farbrother, J. E., Kirov, G., Owen, M. J. and Guggenheim, J. A. 2003. Linkage analysis of 18p, 12q and 17q high myopia loci in 51 UK families. Investigative ophthalmology & visual science 44(E-Abst)
• O'Donovan, M. C. and Owen, M. J. 2003. Genetic findings in psychotic disorders. In: Soares, J. C. and Gershon, S. eds. Handbook of Medical Psychiatry. New York: Marcel Dekker, pp. 417-432.
• Owen, M. J. and O'Donovan, M. C. 2003. Schizophrenia and genetics. In: Plomin, R. et al. eds. Behavioral Genetics in the Postgenomic Era. Washington, DC: APA Books, pp. 463-480., (10.1037/10480-023)
• Green, E. K., Elvidge, G. P., Owen, M. J. and Craddock, N. J. 2003. Mutational analysis of two positional candidate susceptibility genes for bipolar disorder on chromosome 12q23-q24: phenylalanine hydroxylase and human LIM-homeobox LHX5. Psychiatric Genetics 13(2), pp. 97-101. (10.1097/01.ypg.0000057882.80011.9e)
• Børglum, A. et al. 2003. Possible parent-of-origin effect of Dopa decarboxylase in susceptibility to bipolar affective disorder. American Journal of Medical Genetics 117B(1), pp. 18-22. (10.1002/ajmg.b.10030)
• Heron, J., Jones, I. R., Williams, J., Owen, M. J., Craddock, N. J. and Jones, L. 2003. Self-reported schizotypy and bipolar disorder: demonstration of a lack of specificity of the Kings Schizotypy Questionnaire. Schizophrenia Research 65(2-3), pp. 153-158. (10.1016/S0920-9964(03)00004-5)

2002

• Levinson, D. et al. 2002. Is schizophrenia linked to chromosome 1q? Response. Science 298(5602), pp. 2277-2279.
• Sham, P., Bader, J. S., Craig, I., O'Donovan, M. C. and Owen, M. J. 2002. DNA Pooling: a tool for large-scale association studies. Nature Reviews Genetics 3(11), pp. 862-871. (10.1038/nrg930)
• Bray, N. J. et al. 2002. Screening the protocadherin 8 (PCDH8) gene in schizophrenia [Conference Abstract]. American Journal of Medical Genetics 114(7), pp. 844-844.
• Bray, N. J., Buckland, P. R., Williams, H., Norton, N., Williams, N. M., Owen, M. J. and O'Donovan, M. C. 2002. Detection of cis-acting polymorphisms and epigenetic modification affecting gene expression [Conference Abstracts]. American Journal of Medical Genetics 114(7), pp. 750-750. (10.1002/ajmg.10971)
• Dimitrova, A. et al. 2002. Major psychiatric disorders and the serotonin transporter gene (SLC6A4): family-based association studies. Psychiatric Genetics 12(3), pp. 137-141. (10.1097/00041444-200209000-00004)
• Richards, A. J. et al. 2002. Vitreoretinopathy with phalangeal epiphyseal dysplasia, a type II collagenopathy resulting from a novel mutation in the C-propeptide region of the molecule. Journal of Medical Genetics 39(9), pp. 661-665. (10.1136/jmg.39.9.661)
• Wickham, H. et al. 2002. Familiality of clinical characteristics in schizophrenia. Journal of Psychiatric Research 36(5), pp. 325-329. (10.1016/S0022-3956(02)00008-0)
• Bray, N. J. et al. 2002. Screening the human protocadherin 8 (PCDH8) gene in schizophrenia. Genes, Brain and Behavior 1(3), pp. 187-191. (10.1034/j.1601-183X.2002.10307.x)
• Norton, N. et al. 2002. Schizophrenia and functional polymorphisms in the MAOA and COMT genes: No evidence for association or epistasis. American Journal Of Medical Genetics Part A 114(5), pp. 491-496. (10.1002/ajmg.10517)
• Walter, S. et al. 2002. The retained ability to display affection and emotion in Alzheimer's disease. Neurobiology of Aging 23(1), pp. S44-S45.
• Archer, N. et al. 2002. Delusions in dementia - An investigation into their persistence and predictive value. Neurobiology of Aging 23(1), pp. S156-S156.
• Vrieze, F. W. D., Hardy, J., Rudrasingham, V., Owen, M. J. and Lahiri, D. 2002. APP promotor variability as a risk factor for AD. Neurobiology of Aging 23(1), pp. S299-S299.
• Georgieva, L. et al. 2002. Dopamine transporter gene (DAT1) VNTR polymorphism in major psychiatric disorders: family-based association study in the Bulgarian population. Acta Psychiatrica Scandinavica 105(5), pp. 396-399. (10.1034/j.1600-0447.2002.1o174.x)
• Sedvall, O. et al. 2002. The Swedish HUBIN Project on Schizophrenia. European Psychiatry 17(1), pp. 4S-5S. (10.1016/S0924-9338(02)80018-9)
• Jönsson, E. et al. 2002. Association between a functional promoter MAOA variant and schizophrenia. European Psychiatry 17(1), pp. 182S-182S. (10.1016/S0924-9338(02)80781-7)
• Norton, N. et al. 2002. Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools. Human Genetics 110(5), pp. 471-478. (10.1007/s00439-002-0706-6)
• Levinson, D. F. et al. 2002. No major schizophrenia locus detected on chromosome 1q in a large multicenter sample. Science 296(5568), pp. 739-741. (10.1126/science.1069914)
• Myers, A. et al. 2002. Full genome screen for Alzheimer disease: Stage II analysis. American Journal Of Medical Genetics Part A 114(2), pp. 235-244. (10.1002/ajmg.10183)
• Williams, N. M., O'Donovan, M. C. and Owen, M. J. 2002. Genome scans and microarrays: converging on genes for schizophrenia?. Genome Biology 3(4), pp. Reviews1011-Reviews1011.5.
• Garpenstrand, H. et al. 2002. A regulatory monoamine oxidase a promoter polymorphism and personality traits. Neuropsychobiology 46(4), pp. 190-193. (10.1159/000067804)
• Jones, I. R., Jacobsen, N., Green, E. K., Elvidge, G. P., Owen, M. J. and Craddock, N. J. 2002. Evidence for familial cosegregation of major affective disorder and genetic markers flanking the gene for Darier's disease. Molecular Psychiatry 7(4), pp. 424-427.
• Henry, J. C., van Amelsvoort, T., Morris, R. G., Owen, M. J., Murphy, D. G. M. and Murphy, K. C. 2002. An investigation of the neuropsychological profile in adults with velo-cardio-facial syndrome (VCFS). Neuropsychologia 40(5), pp. 471-478. (10.1016/S0028-3932(01)00136-1)
• Anney, R. et al. 2002. Characterisation, mutation detection, and association analysis of alternative promoters and 5' UTRs of the human dopamine D3 receptor gene in schizophrenia. Molecular psychiatry 7(5), pp. 493-502. (10.1038/sj.mp.4001003)
• Jones, I. R., Jacobsen, N. J. O., Green, E. K., Elvidge, G. P., Owen, M. J. and Craddock, N. J. 2002. Evidence for familial cosegregation of major affective disorder and genetic markers flanking the gene for Darier's disease. Molecular psychiatry 7(4), pp. 424-427. (10.1038/sj.mp.4000989)
• Williams, N. M. et al. 2002. Mutation screening and LD mapping in the VCFS deleted region of chromosome 22q11 in schizophrenia using a novel DNA pooling approach. Molecular Psychiatry 7(10), pp. 1092-1100. (10.1038/sj.mp.4001188)
• Rees, M. I. et al. 2002. Hyperekplexia associated with compound heterozygote mutations in the β-subunit of the human inhibitory glycine receptor (GLRB). Human Molecular Genetics 11(7), pp. 853-860. (10.1093/hmg/11.7.853)
• Williams, N. M. et al. 2002. Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor. Molecular Psychiatry 7(5), pp. 508-514. (10.1038/sj.mp.4001030)
• Thapar, A. and Scourfield, J. 2002. Childhood disorders. In: McGuffin, P., Owen, M. J. and Gottesman, I. I. eds. Psychiatric Genetics and Genomics. Oxford Medical Publications Oxford: Oxford University Press, pp. 147-181.
• Scourfield, J. and Owen, M. J. 2002. Genetic counselling. In: McGuffin, P., Owen, M. J. and Gottesman, I. I. eds. Psychiatric Genetics and Genomics. Oxford Medical Publications Oxford: Oxford University Press, pp. 415-424.
• Zammit, S., O'Donovan, M. C. and Owen, M. J. 2002. Neurogenetics of schizophrenia. In: D'haenen, H., den Boer, J. A. and Willner, P. eds. Biological Psychiatry. Chichester: Wiley, pp. 663-671., (10.1002/0470854871.chxvii9)
• Tsuang, M. T. and Owen, M. J. 2002. Molecular and population genetics of schizophrenia. In: Davis, K. L. et al. eds. Neuropsychopharmacology - 5th Generation of Progress. Philadelphia, PA: Lippincott, Williams and Wilkins, pp. 671-687.
• West, A. et al. 2002. Evidence to suggest biased phenotypes in children with Attention Deficit Hyperactivity Disorder from completely ascertained trios. Molecular Psychiatry 7(9), pp. 962-966. (10.1038/sj.mp.4001129)
• Sklar, P. et al. 2002. Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Molecular Psychiatry 7(6), pp. 579. (10.1038/sj.mp.4001058)
• Bennett, P. et al. 2002. The Wellcome trust UK-Irish bipolar affective disorder sibling-pair genome screen: first stage report. Molecular Psychiatry 7(2), pp. 189-200. (10.1038/sj.mp.4000957)
• Holmes, J. et al. 2002. Association of DRD4 in children with ADHD and comorbid conduct problems. American Journal of Medical Genetics 114(2), pp. 150-153. (10.1002/ajmg.10149)
• Hawi, Z. et al. 2002. Serotonergic system and attention deficit hyperactivity disorder (ADHD): a potential susceptibility locus at the 5-HT(1B) receptor gene in 273 nuclear families from a multi-centre sample. Molecular Psychiatry 7(7), pp. 718-725. (10.1038/sj.mp.4001048)

2001

• Payton, A. et al. 2001. Susceptibility genes for a trait measure of attention deficit hyperactivity disorder: a pilot study in a non-clinical sample of twins. Psychiatry Research 105(3), pp. 273 -278. (10.1016/S0165-1781(01)00342-0)
• Jurewicz, I., Owen, R., O'Donovan, M. C. and Owen, M. J. 2001. Searching for susceptibility genes in schizophrenia. European Neuropsychopharmacology 11(6), pp. 395-398. (10.1016/S0924-977X(01)00116-X)
• Abraham, R. et al. 2001. Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease. Human Genetics 109(6), pp. 646-652. (10.1007/s00439-001-0614-1)
• Plomin, R. et al. 2001. A genome-wide scan of 1842 DNA markers for allelic associations with general cognitive ability: a five-stage design using DNA pooling and extreme selected groups. Behaviour Genetics 31(6), pp. 497-509. (10.1023/A:1013385125887)
• Murphy, K. C. and Owen, M. J. 2001. Velo-cardio-facial syndrome: a model for understanding the genetics and pathogenesis of schizophrenia. British Journal of Psychiatry 179(5), pp. 397-402. (10.1192/bjp.179.5.397)
• Jones, R. G., Morley-Canellas, J., Owen, M. J. and Murphy, K. C. 2001. Chromosome 22q11 deletions and severe learning disability [comment]. The British Journal of Psychiatry 179(5), pp. 466-467. (10.1192/bjp.179.5.466-a)
• Kirov, G., Lowry, C. A., Stephens, M., Oldfield, S., O'Donovan, M. C., Lightman, S. L. and Owen, M. J. 2001. Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder. Molecular Psychiatry 6(6), pp. 671-677. (10.1038/sj.mp.4000899)
• Stephens, M., Kirov, G. and Owen, M. J. 2001. ADARB1, a brain specific member of the RNA-specific adenosine deaminase family and bipolar affective disorder. American Journal of Medical Genetics 105(7), pp. 622-622.
• Kirov, G., Stehens, M. and Owen, M. J. 2001. Screening of three candidate genes in the bipolar candidate region on chromosome 21q22.3. American Journal of Medical Genetics 105(7), pp. 612-612.
• Green, E. K., Elvidge, G., Jones, I. R., Owen, M. J. and Craddock, N. J. 2001. Mutational analysis of 2 positional candidate susceptibility genes for bipolar disorder: PAH and LHX5. American Journal of Medical Genetics 105(7), pp. 610-611.
• Williams, H., Kirov, G., Meyer, J., Lesch, K. P. and Owen, M. J. 2001. Further analysis of KIAA0027 in schizophrenic patients. American Journal of Medical Genetics 105(7), pp. 561-561.
• Reid, S. J. et al. 2001. Expression and population studies of the TATA-box binding protein polyglutamine region at normal and expanded lengths.. American Journal of Human Genetics 69(4), pp. 424-424.
• Hamshere, M. L., Giles, P., Krawczak, M. and Owen, M. J. 2001. Statistical analysis of genotypic association data with HAPMAXII. AMERICAN JOURNAL OF HUMAN GENETICS 69(4), pp. 390-390.
• Rees, M. I. et al. 2001. A missense mutation of human Gephyrin (GPHN) is associated with Hyperekplexia and transcript isoform analysis re-defines the genomic structure of GPHN. American Journal of Human Genetics 69(4), pp. 627-627.
• Jones, G. et al. 2001. Aggressive behaviour in patients with schizophrenia is associated with catechol-O-methyltransferase genotype. British Journal of Psychiatry 179(4), pp. 351-355. (10.1192/bjp.179.4.351)
• Rees, M. I. et al. 2001. Compound heterozygosity and nonsense mutations in the alpha(1)-subunit of the inhibitory glycine receptor in hyperekplexia. Hum Genet 109(3), pp. 267-270.
• Owen, M. J. 2001. Simple and complex genetics of Alzheimer's disease. Journal of Medical Genetics 38, pp. S29-S29.
• 2001. Evidence of association between DRD4 and ADHD with conduct disturbance. Presented at: Behavior Genetics Association Meeting, Cambridge, 11 July 2001 Presented at Thapar, A. et al. eds.Behavior Genetics, Vol. 31. Behavior Genetics Association Meeting Abstracts Vol. 5. Springer Verlag pp. 470-471.
• Campbell, L. E. et al. 2001. Neuropsychological profile of children with Velo-cardio-facial syndrome (VCFS). Journal of Medical Genetics 38, pp. S39-S39.
• Liddell, M., Lovestone, S. and Owen, M. J. 2001. Advising relatives of risk of Alzheimer's disease - Authors' reply. British Journal of Psychiatry 179(1), pp. 73-74. (10.1192/bjp.179.1.73)
• Payton, A. et al. 2001. Examining for association between candidate gene polymorphisms in the dopamine pathway and attention-deficit hyperactivity disorder: a family-based study. Neuroscience Letters 105(5), pp. 464-470. (10.1002/ajmg.1407)
• Bowen, T. et al. 2001. Mutation screening of the KCNN3 gene reveals a rare frameshift mutation [Letter]. Molecular Psychiatry 6(3), pp. 259-260. (10.1038/sj.mp.4000128)
• van Amelsvoort, T. et al. 2001. Structural brain abnormalities associated with deletion at chromosome 22q11. British Journal of Psychiatry(178), pp. 412-419. (10.1192/bjp.178.5.412)
• Wang, E. C. Y., Thern, A., Denzel, A., Kitson, J., Farrow, S. N. and Owen, M. J. 2001. DR3 regulates negative selection during thymocyte development. Molecular and cellular biology 21(10), pp. 3451-61. (10.1128/MCB.21.10.3451-3461.2001)
• Williams, H. J., Murphy, K. C., Spurlock, G. and Owen, M. J. 2001. No association between a promoter polymorphism of the UFD1L gene and schizophrenia in individuals with or without velo-cardio-facial syndrome (VCFS). Schizophrenia Research 49, pp. 81-81.
• Bray, N. J. and Owen, M. J. 2001. Searching for schizophrenia genes. Trends in Molecular Medicine 7(4), pp. 169-174.
• Jones, L. A., Cardno, A. G., Sanders, R. D., Owen, M. J. and Williams, J. 2001. Sustained and selective attention as measures of genetic liability to schizophrenia. Schizophrenia Research 48(2-3), pp. 263-267.
• Wickham, H. et al. 2001. Familiality of symptom dimensions in schizophrenia. Schizophrenia Research 47(2-3), pp. 223-232. (10.1016/S0920-9964(00)00098-0)
• Turic, D., Fisher, P. J., Plomin, R. and Owen, M. J. 2001. No association between apolipoprotein E polymorphisms and general cognitive ability in children. Neuroscience Letters 299(1-2), pp. 97-100. (10.1016/S0304-3940(00)01789-4)
• Wang, E. C. Y., Kitson, J., Thern, A., Williamson, J., Farrow, S. N. and Owen, M. J. 2001. Genomic structure, expression, and chromosome mapping of the mouse homologue for the WSL-1 (DR3, Apo3, TRAMP, LARD, TR3, TNFRSF12) gene. Immunogenetics 53(1), pp. 59-63. (10.1007/s002510000290)
• Liddell, M. B., Lovestone, S. and Owen, M. J. 2001. Genetic risk of Alzheimer's disease: advising relatives. British Journal of Psychiatry 178(1), pp. 7-11. (10.1192/bjp.178.1.7)
• Jacobsen, N. J. O., Elvidge, G., Franks, E. K. E., O'Donovan, M. C., Craddock, N. J. and Owen, M. J. 2001. CUX2, a potential regulator of NCAM expression: Genomic characterization and analysis as a positional candidate susceptibility gene for bipolar disorder. American Journal of Medical Genetics 105(3), pp. 295-300. (10.1002/ajmg.1325)
• Elvidge, G., Jones, I. R., McCandless, F., Asherson, P., Owen, M. J. and Craddock, N. J. 2001. Allelic variation of aBalI polymorphism in the DRD3 gene does not influence susceptibility to bipolar disorder: Results of analysis and meta-analysis. American Journal of Medical Genetics 105(4), pp. 307-311. (10.1002/ajmg.1353)
• Jacobsen, N. J. O. et al. 2001. Exclusion of the Darier's disease gene, ATP2A2, as a common susceptibility gene for bipolar disorder. Molecular Psychiatry 6(1), pp. 92-97. (10.1038/sj.mp.4000774)
• Williams, N. et al. 2001. Screening of candidate genes related to myelination for mutations associated with schizophrenia. American Journal of Medical Genetics - Neuropsychiatric Genetics 105(7), pp. 589.

2000

• Myers, A. et al. 2000. Susceptibility locus for Alzheimer's disease on chromosome 10. Science 290(5500), pp. 2304-2305. (10.1126/science.290.5500.2304)
• Vincent, J. B. et al. 2000. Long repeat tracts at SCA8 in major psychosis. American Journal of Medical Genetics 96(6), pp. 873-876. (10.1002/1096-8628(20001204)96:6<873::AID-AJMG37>3.0.CO;2-9)
• Sham, P. C. et al. 2000. GENESiS: creating a composite index of the vulnerability to anxiety and depression in a community-based sample of siblings. Twin Research 3(4), pp. 316-322. (10.1375/136905200320565292)
• Bowen, T. et al. 2000. No evidence of association from transmission disequilibrium analysis of the hKCa3 gene in bipolar disorder. Bipolar Disorders 2(4), pp. 328-331. (10.1034/j.1399-5618.2000.020406.x)
• Deb, S., Williams, J. and Owen, M. J. 2000. Apolipoprotein E, Alzheimer's disease and Down's syndrome - Reply. British Journal of Psychiatry 177, pp. 469-470.
• Jones, L. A. et al. 2000. The kings schizotypy questionnaire as a quantitative measure of schizophrenia liability. Schizophrenia Research 45(3), pp. 213-221. (10.1016/S0920-9964(99)00183-8)
• Snell, R. G., Miller, J., Owen, M. J. and Rees, M. I. 2000. Genomic structure of postsynaptic organizational protein, Gephyrin, and mutation analysis in hyperekplexia and startle phenotypes. American Journal of Human Genetics 67(4), pp. 385-385.
• Rees, M. I., Lewis, T. M., Mortier, G., Snell, R. G., Schofield, P. R. and Owen, M. J. 2000. A transient hyperekplexia phenotype associated with compound heterozygote mutations in the human beta-subunit of the inhibitory glycine receptor (GLRB). American Journal of Human Genetics 67(4), pp. 391-391.
• Austin, J. et al. 2000. The high affinity neurotensin receptor gene (NTSR1): comparative sequencing and association studies in schizophrenia. Molecular Psychiatry 5(5), pp. 552-557. (10.1038/sj.mp.4000761)
• Murphy, K. C. et al. 2000. Chromosome 22q, velo-cardio-facial syndrome (VCFS) and schizophrenia. Journal of Medical Genetics 37, pp. S58-S58.
• van Amelsvoort, T. et al. 2000. Brain abnormalities associated with deletions at 22q11: Implications for psychosis. Journal of Medical Genetics 37, pp. S26-S26.
• Holmes, J. et al. 2000. A family-based and case-control association study of the dopamine D4 receptor gene and dopamine transporter gene in attention deficit hyperactivity disorder. Molecular Psychiatry 5(5), pp. 523-530. (10.1038/sj.mp.4000751)
• Levinson, D. F. et al. 2000. Multicenter linkage study of schizophrenia candidate regions on chromosomes 5q, 6q, 10p, and 13q: schizophrenia linkage collaborative group III. American Journal of Human Genetics 67(3), pp. 652-663. (10.1086/303041)
• Williams, H., Murphy, K., Spurlock, G., O'Donovan, M. and Owen, M. 2000. No association of the -277A variant allele of the UFD1L promoter polymorphism and schizophrenia. American Journal of Medical Genetics - Neuropsychiatric Genetics 96(4), pp. 533-534.
• Van Amelsvoort, T. et al. 2000. Brain abnormalities associated with deletions at 22q11: Implicatons for psychosis. American Journal of Medical Genetics 96(4), pp. 551-551.
• Kirov, G., Stephens, M. and Owen, M. J. 2000. Examining the 4p16 region for association with bipolar disorder using DNA pooling. American Journal of Medical Genetics 96(4), pp. 548-548.
• Walters, S. E., Williams, N. M., Spurlock, G., Sanders, R. D., McCarthy, G. M., Cardno, A. G. and Owen, M. J. 2000. Identification of a polymorphism in the human NURR1 gene and investigation of an association with schizophrenia. American Journal of Medical Genetics 96(4), pp. 535-535.
• Payton, A. et al. 2000. A family based candidate gene association study of Attention Deficit Hyperactivity Disorder. American Journal of Medical Genetics 96(4), pp. 489-489.
• Murphy, K. C. and Owen, M. J. 2000. Evidence for association between polymorphisms of the catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO) genes and schizophrenia in adults with velo-cardio-facial syndrome.. American Journal of Medical Genetics 96(4), pp. 476-476.
• Henry, J. C., van Amelsvoort, T., Morris, R. G., Owen, M. J., Murphy, K. C. and Murphy, D. G. M. 2000. The neuropsychological profile in adults with velo-cardio-facial syndrome (VCFS).. American Journal of Medical Genetics 96(4), pp. 474-474.
• McCarthy, G. M. et al. 2000. Investigating familiality of subtypes in schizophrenia. American Journal of Medical Genetics 96(4), pp. 473-474.
• Bray, N. J., Jacobsen, N., Spurlock, G., Austin, J., Williams, H. and Owen, M. J. 2000. A functional and positional candidate gene for schizophrenia. American Journal of Medical Genetics 96(4), pp. 461-462.
• Elvidge, G. P., Owen, M. J. and Craddock, N. J. 2000. Mutational analysis of purinergic receptor, P2X4: A positional candidate susceptibility gene for bipolar disorder.. American Journal of Medical Genetics 96(4), pp. 493-493.
• Jacobsen, N. J., Franks, E. K., Craddock, N. J. and Owen, M. J. 2000. Genomic characterisation and mutational analysis of CUX2, a potential regulator of NCAM expression, mapping to chromosome 12q23-q24.1.. American Journal of Medical Genetics 96(4), pp. 493-494.
• Fitzpatrick, E., Spurlock, G., Coleman, S. L., Owen, M. J. and Buckland, P. R. 2000. Association studies of polymorphisms in the promoter region of the dopamine D4 receptor and the D2 receptor [Abstract]. American Journal of Medical Genetics 96(4), pp. 530-530. (10.1002/1096-8628(20000807)96:4<515::AID-AJMG6>3.0.CO;2-U)
• Bray, N. J. et al. 2000. No evidence for association between a non-synonymous polymorphism in the gene encoding human metabotropic glutamate receptor 7 and schizophrenia. Psychiatric Genetics 10(2), pp. 83-86. (10.1097/00041444-200010020-00005)
• Jonsson, E. G., Norton, N., Gustavsson, J. P., Oreland, L., Owen, M. J. and Sedvall, G. C. 2000. A promoter polymorphism in the monoamine oxidase A gene and its relationships to monoamine metabolite concentrations in CSF of healthy volunteers. Journal of Psychiatric Research 34(3), pp. 239-244. (10.1016/S0022-3956(00)00013-3)
• Deb, S., Braganza, J., Norton, N., Williams, H., Kehoe, P. G., Williams, J. and Owen, M. J. 2000. APOE epsilon 4 influences the manifestation of Alzheimer's disease in adults with Down's syndrome. British Journal of Psychiatry 176, pp. 468-472. (10.1192/bjp.176.5.468)
• Middle, F. et al. 2000. Bipolar disorder and variation at a common polymorphism (A1832G) within exon 8 of the Wolfram gene. American Journal of Medical Genetics 96(2), pp. 154-157. (10.1002/(sici)1096-8628(20000403)96:2%3C154::aid-ajmg5%3E3.0.co;2-f)
• Morris, D. W. et al. 2000. Family-based association mapping provides evidence for a gene for reading disability on chromosome 15q. Human Molecular Genetics 9(5), pp. 843-848. (10.1093/hmg/9.5.843)
• Owen, M. J. 2000. Molecular genetic studies of schizophrenia. Brain research. Brain research reviews 31(2-3), pp. 179-186. (10.1016/S0165-0173(99)00035-1)
• Austin, J. et al. 2000. Association analysis of the proneurotensin gene and bipolar disorder. Psychiatric Genetics 10(1), pp. 51-54. (10.1097/00041444-200010010-00009)
• Austin, J. et al. 2000. Comparative sequencing of the proneurotensin gene and association studies in schizophrenia. Molecular Psychiatry 5(2), pp. 208-212. (10.1038/sj.mp.4000693)
• Bowen, T. et al. 2000. Repeat sizes at CAG/CTG loci CTG18.1, ERDA1 and TGC13-7a in schizophrenia. Psychiatric Genetics 10(1), pp. 33-37. (10.1097/00041444-200010010-00006)
• Farmer, A. E., Owen, M. J. and McGuffin, P. 2000. Bioethics and genetic research in psychiatry. British Journal of Psychiatry 176, pp. 105-108. (10.1192/bjp.176.2.105)
• Rees, M. I., Watts, P., Fenton, I., Clarke, A., Snell, R. G., Owen, M. J. and Gray, J. 2000. Further evidence of autosomal dominant congenital zonular pulverulent cataracts linked to 13q11 (CZP3) and a novel mutation in connexin 46 (GJA3).. Human Genetics 106(2), pp. 206-209. (10.1007/s004390051029)
• Tunstall, N. et al. 2000. Familial influence on variation in age of onset and behavioural phenotype in Alzheimer's disease. British Journal of Psychiatry 176, pp. 156-159. (10.1192/bjp.176.2.156)
• Buckland, J., Pennington, D. J., Bruno, L. and Owen, M. J. 2000. Co-ordination of the expression of the protein tyrosine kinase p56(lck) with the pre-T cell receptor during thymocyte development. European Journal of Immunology 30(1), pp. 8-18. (10.1002/1521-4141(200001)30:1<8::AID-IMMU8>3.0.CO;2-8)
• Owen, M. J., Cardno, A. G. and O'Donovan, M. C. 2000. Psychiatric genetics: back to the future. Molecular Psychiatry 5(1), pp. 22-31. (10.1038/sj.mp.4000702)
• Kirov, G., Stephens, M., Williams, N. M., O'Donovan, M. C. and Owen, M. J. 2000. Automated genotyping of single-nucleotide polymorphisms by extension of fluorescently labelled primers: analysis of individual and pooled DNA samples. Balkan Journal of Medical Genetics 3, pp. 23-28.
• Cardno, A. G., O'Donovan, M. C. and Owen, M. J. 2000. Genetic risk factors for schizophrenia. International Journal of Mental Health 29(3), pp. 13-38.
• Deb, S., Braganza, J., Norton, N., Williams, H., Kehoe, P. G., Williams, J. and Owen, M. J. 2000. Presence of the Apolipoprotein E e4 allele is associated with the manifestation of Alzheimer dementia in adults with Down syndrome. Journal of Intellectual Disability Research 44, pp. 259-259.
• Murphy, K. and Owen, M. J. 2000. No association between polymorphisms of catechol-o-methyltransferase (COMT) or monoamine oxidase (MAO) genes and schizophrenia in adults with velo-cardio-facial syndrome. Schizophrenia Research 41(1), pp. 96. (10.1016/S0920-9964(00)90531-0)
• Murphy, K., Jones, L. and Owen, M. J. 2000. High rates of schizophrenia in adults with velo-cardio-facial syndrome (VCFS). Schizophrenia Research 41(1), pp. 29-29. (10.1016/S0920-9964(00)90364-5)
• Kirov, G., Williams, N. M., Sham, P., Craddock, N. J. and Owen, M. J. 2000. Pooled genotyping of microsatellite markers in parent-offspring trios. Genome Research 10(1), pp. 105-115.
• Speight, G. et al. 2000. Comparative sequencing and association studies of aromatic L-amino acid decarboxylase in schizophrenia and bipolar disorder. Molecular Psychiatry 5(3), pp. 327-331. (10.1038/sj.mp.4000717)
• Hoogendoorn, B. et al. 2000. Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools. Human Genetics 107(5), pp. 488-493. (10.1007/s004390000397)
• Watts, P., Rees, M. I., Clarke, A. J., Beck, L., Lane, C. M., Owen, M. J. and Gray, J. 2000. Linkage analysis in an autosomal dominant 'zonular nuclear pulverulent' congenital cataract, mapped to chromosome 13q11-13. Eye 14(2), pp. 172-175. (10.1038/eye.2000.48)
• Williams, N. et al. 2000. Identification and characterisation of SNPs in candidate genes for schizophrenia. American Journal of Medical Genetics - Neuropsychiatric Genetics 96(4), pp. 462.
• Williams, N. et al. 2000. Linkage disequilibrium mapping and candidate gene screening of the VCFS deleted region for mutations associated with schizophrenia. American Journal of Medical Genetics - Neuropsychiatric Genetics 96(4), pp. 475.

1999

• Kirov, G., Norton, N., Jones, I. R., McCandless, F., Craddock, N. J. and Owen, M. J. 1999. A functional polymorphism in the promoter of monoamine oxidase A gene and bipolar affective disorder. International Journal of Neuropsychopharmacology 2(4), pp. 293-298. (10.1017/s1461145799001601)
• Kirov, G., Jones, I. R., McCandless, F., Craddock, N. J. and Owen, M. J. 1999. Family-based association studies of bipolar disorder with candidate genes involved in dopamine neurotransmission: DBH, DAT1, COMT, DRD2, DRD3 and DRD5. Molecular Psychiatry 4(6), pp. 558-565.
• Willliams, H., Bray, N. J., Murphy, K. C., Cardno, A. G., Jones, L. A. and Owen, M. J. 1999. No evidence for allelic association between schizophrenia and a functional variant of the human dopamine beta-hydroxylase gene (DBH).. American Journal Of Medical Genetics Part A 88(5), pp. 557-559. (10.1002/(SICI)1096-8628(19991015)88:5<557::AID-AJMG22>3.0.CO;2-F)
• Murphy, K. C., Jones, L. A. and Owen, M. J. 1999. High rates of schizophrenia in adults with velo-cardio-facial syndrome. Archives of General Psychiatry 56(10), pp. 940-945. (10.1001/archpsyc.56.10.940)
• Kirov, G. and Owen, M. J. 1999. Identification of new microsatellite markers on chromosome 4p16. American Journal of Human Genetics 65(4), pp. A257-A257.
• Murphy, K. C., Jones, L. A. and Owen, M. J. 1999. High rates of schizophrenia in velo-cardio-facial syndrome. American Journal of Human Genetics 65(4), pp. A336-A336.
• Bowen, T. et al. 1999. Linkage studies of bipolar disorder with chromosome 18 markers. American Journal of Medical Genetics 15(88), pp. 503-509. (10.1002/(SICI)1096-8628(19991015)88:5<503::AID-AJMG13>3.0.CO;2-U)
• McCarthy, G. et al. 1999. Intra-pair correlations of symptom dimensions in a sibling pair study of schizophrenia. Molecular Psychiatry 4, pp. S26-S27.
• Fisher, P. J. et al. 1999. A high resolution genome scan made possible with DNA pooling. Molecular Psychiatry 4(1), pp. S10-S10.
• Owen, M. J. 1999. Evidence of novel loci in late onset Alzheimer's disease. Molecular Psychiatry 4(1), pp. S9-S9.
• Murphy, K. C. and Owen, M. J. 1999. No association between polymorphisms of catechol-O-methyltransferase (COMT) or monoamine oxidase (MAO) genes and schizophrenia in adults with velo-cardio-facial syndrome. Journal of Medical Genetics 36, pp. S78-S78.
• Murphy, K., Thompson, P. W., Davies, S. J., Groves, P., Owen, M. J. and Stuart, G. 1999. The prevalence of chromosome 22q11 deletions in an adult congenital heart disease population. Journal of Medical Genetics 36, pp. S59-S59.
• Jones, L. A., Sanders, R. D., Cardno, A. G., Owen, M. J. and Williams, J. 1999. Sustained and selective attention as quantitative measures of schizophrenia liability. Molecular Psychiatry 4, pp. S117-S117.
• Emilien, G., Maloteaux, J., Geurts, M. and Owen, M. J. 1999. Dopamine receptors and schizophrenia: contribution of molecular genetics and clinical neuropsychology. The International Journal of Neuropsychopharmacology 2(3), pp. 197. (10.1017/S1461145799001479)
• Williams, H. J. et al. 1999. Characterization, mutational analysis, and association of the human proline oxidase gene: A candidate gene for schizophrenia.. Molecular Psychiatry 4, pp. S115-S115.
• Sanders, R. D., Norton, N., Williams, J. and Owen, M. J. 1999. Pre-pulse inhibition in the functional psychoses. Molecular Psychiatry 4, pp. S121-S121.
• Hill, L. et al. 1999. IGF2R and cognitive ability. Molecular Psychiatry 4, pp. S108-S108.
• Jonsson, E. G., Norton, N., Gustavsson, J. P., Oreland, L., Owen, M. J. and Sedvall, G. C. 1999. Monoamine oxidase a promoter polymorphism and relationships to monoamine metabolite concentrations in CSF. Molecular Psychiatry 4, pp. S97-S98.
• Norton, N. et al. 1999. No evidence for association between schizophrenia and MAO-A promoter polymorphism. Molecular Psychiatry 4, pp. S96-S96.
• Middle, F. A. et al. 1999. Association studies between bipolar disorder and a polymorphism in the Wolfram gene. Molecular Psychiatry 4, pp. S76-S76.
• Jones, I. R., Owen, M. J. and Craddock, N. J. 1999. Further evidence of familial cosegregation of major affective disorder and Darier's disease. Molecular Psychiatry 4, pp. S73-S73.
• Thapar, A. et al. 1999. A quantitative trait loci study of attention deficit hyperactivity disorder. Molecular Psychiatry 4, pp. S52-S53.
• McCarthy, G. et al. 1999. Familial aggregation of clinical variables in a sibling pair study of schizophrenia. Molecular Psychiatry 4, pp. S121-S121.
• Williams, N. M. et al. 1999. A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs. Human Molecular Genetics 8(9), pp. 1729-1739. (10.1093/hmg/8.9.1729)
• O'Donovan, M. C. and Owen, M. J. 1999. Candidate-gene association studies of schizophrenia. American Journal of Human Genetics 65(3), pp. 587-592. (10.1086/302560)
• Bray, N. J., Cardno, A. G., Fitzpatrick, E. R., Buckland, P. R. and Owen, M. J. 1999. Embryonic NCAM and schizophrenia: Genetic analysis of regulatory enzymes. Molecular Psychiatry 4, pp. S32-S32.
• Jacobsen, N. J. et al. 1999. ATP2A2 mutations in Darier's disease and their relationship to neuropsychiatric phenotypes. Human Molecular Genetics 8(9), pp. 1631-1636. (10.1093/hmg/8.9.1631)
• Kirov, G., Rees, M., Jones, I. R., McCandless, F., Owen, M. J. and Craddock, N. J. 1999. Bipolar disorder and the serotonin transporter gene: a family-based association study. Psychological Medicine -London- 29(5), pp. 1249-1254. (10.1017/s003329179900882x)
• Williams, N. M., Bowen, T., Kirov, G., Williams, H., Hoogendorn, B., Asherson, P. and Owen, M. J. 1999. Polymorphism screening and association studies of the Wolfram syndrome gene in schizophrenia. Molecular Psychiatry 4(supp1), pp. S42-S42.
• Guy, C., Bowen, T., Jones, I. R., McCandless, F., Owen, M. J., Craddock, N. J. and O'Donovan, M. C. 1999. CTG18.1 and ERDA-1 CAG/CTG repeat size in bipolar disorder. Neurobiology of Disease 6(4), pp. 302-307. (10.1006/nbdi.1999.0249)
• Wavrant-De Vrieze, F. et al. 1999. Genetic variability at the amyloid-beta precursor protein locus may contribute to the risk of late-onset Alzheimer's disease. Neuroscience Letters 269(2), pp. 67-70.
• Owen, M. J. and Cardno, A. G. 1999. Psychiatric genetics: progress, problems, and potential. The Lancet 354(1), pp. SI11-SI14. (10.1016/S0140-6736(99)90242-8)
• Rees, M. I. et al. 1999. Autosome search for schizophrenia susceptibility genes in multiply affected families. Molecular Psychiatry 4(4), pp. 353-359. (10.1038/sj.mp.4000521)
• Cardno, A. G. et al. 1999. CAG repeat length in the hKCa3 gene and symptom dimensions in schizophrenia. Biological Psychiatry 45(12), pp. 1592-1596. (10.1016/s0006-3223(99)00033-5)
• Williams, J., Kehoe, P. G. and Owen, M. J. 1999. Case-control study of presenelin-1 intronic polymorphism. Journal of Neurology, Neurosurgery & Psychiatry 66(6), pp. 702. (10.1136/jnnp.66.6.702)
• Fisher, P. J. et al. 1999. DNA pooling identifies QTLs on chromosome 4 for general cognitive ability in children. Human Molecular Genetics 8(5), pp. 915-922. (10.1093/hmg/8.5.915)
• Jacobsen, N. J., Franks, E. K., Owen, M. J. and Craddock, N. J. 1999. Mutational analysis of phospholipase A2A: a positional candidate susceptibility gene for bipolar disorder. Molecular Psychiatry 4(3), pp. 274-279. (10.1038/sj.mp.4000476)
• Amelsvoort, T. V. et al. 1999. An MRI and fMRI study on the effect of deletions on chromosome 22 on brain. Biological psychiatry 45(8), pp. 110S-111S.
• Hill, L. et al. 1999. DNA pooling and dense marker maps: a systematic search for genes for cognitive ability. NeuroReport 10(4), pp. 843-848. (10.1097/00001756-199903170-00032)
• Wavrant-DeVrieze, F. et al. 1999. No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease. Neuroscience Letters 262(2), pp. 137-139. (10.1016/S0304-3940(99)00035-X)
• Sakuntabhai, A. et al. 1999. Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease. Nature Genetics 21(3), pp. 271-277.
• Franks, E., Guy, C., Jacobsen, N., Bowen, T., Owen, M. J., O'Donovan, M. C. and Craddock, N. J. 1999. Eleven trinucleotide repeat loci that map to chromosome 12 excluded from involvement in the pathogenesis of bipolar disorder. American Journal of Medical Genetics 88(1), pp. 67-70. (10.1002/(SICI)1096-8628(19990205)88:1<67::AID-AJMG12>3.0.CO;2-#)
• Guy, C. et al. 1999. No association between a polymorphic CAG repeat in the human potassium channel gene hKCa3 and bipolar disorder. American Journal of Medical Genetics 88(1), pp. 57-60. (10.1002/(sici)1096-8628(19990205)88:1%3C57::aid-ajmg10%3E3.0.co;2-6)
• Kehoe, P. et al. 1999. A full genome scan for late onset Alzheimer's disease. Human Molecular Genetics 8(2), pp. 237-245. (10.1093/hmg/8.2.237)
• Kehoe, P., Krawczak, M., Harper, P. S., Owen, M. J. and Jones, L. 1999. Age of onset in Huntington disease: sex specific influence of apolipoprotein E genotype and normal CAG repeat length. Journal of Medical Genetics 36(2), pp. 108-111. (10.1136/jmg.36.2.108)
• Kehoe, P. G. et al. 1999. Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. Nature Genetics 21(1), pp. 71-72. (10.1038/5009)
• Kerwin, R. and Owen, M. J. 1999. Genetics of novel therapeutic targets in schizophrenia. The British journal of psychiatry. Supplement. 38, pp. 1-4.
• Hoogendoorn, B., Owen, M. J., Oefner, P. J., Williams, N. M., Austin, J. and O'Donovan, M. C. 1999. Genotyping single nucleotide polymorphisms by primer extension and high performance liquid chromatography. Human Genetics 104(1), pp. 89-93. (10.1007/s004390050915)
• Cardno, A. G., Jones, L. A., Murphy, K. C., Sanders, R. D., Asherson, P., Owen, M. J. and McGuffin, P. 1999. Dimensions of psychosis in affected sibling pairs. Schizophrenia Bulletin 25(4), pp. 841-850.
• Kirov, G., Owen, M. J., Jones, I., McCandless, F. and Craddock, N. J. 1999. Tryptophan hydroxylase gene and manic-depressive illness [letter]. Archives of General Psychiatry 56(1), pp. 98-99. (10.1001/archpsyc.56.1.98)

1998

• Kehoe, P. G., Williams, H., Holmans, P. A., Wilcock, G., Cairns, N. J., Neal, J. and Owen, M. J. 1998. The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease. Journal of Medical Genetics 35(12), pp. 1034-1035. (10.1136/jmg.35.12.1034)
• Spurlock, G., Williams, N. M., Williams, H. and Owen, M. J. 1998. Polymorphism screening of the human type 1 sigma (sigma) receptor (a candidate gene for schizophrenia) using a modified dideoxy fingerprinting technique.. American Journal of Medical Genetics 81(6), pp. 525-526.
• Poulton, K. et al. 1998. A molecular genetic study of hyperkinetic disorder/attention deficit hyperactivity disorder. American Journal of Medical Genetics 81(6), pp. 458-458.
• Williams, N. M., Fenton, I. and Owen, M. J. 1998. PsycheMap - An interactive Internet-based database of psychiatric genetics linkage, association, and genome mapping projects. American Journal of Medical Genetics 81(6), pp. 463-464.
• Fisher, P. J. et al. 1998. DNA pooling for genomic scanning - Application to an association study. American Journal of Medical Genetics 81(6), pp. 469-469.
• Kirov, G., Jones, I. R., McCandless, F., Craddock, N. J. and Owen, M. J. 1998. Family-based association studies of candidate genes in bipolar disorder. American Journal of Medical Genetics 81(6), pp. 476-477.
• Williams, N. M., Kirov, G., Craddock, N. J. and Owen, M. J. 1998. Screening the critical region on chromosome 4p with DNA pooling for association with bipolar disorder. American Journal of Medical Genetics 81(6), pp. 486-486.
• Bennett, P., Mulcahy, T., Owen, M. J., Craddock, N. J. and Gill, M. 1998. The Wellcome Trust UK-Irish Bipolar Sib-pair Study: Chromosome 21. American Journal of Medical Genetics 81(6), pp. 541-541.
• Hill, L. et al. 1998. QTLs for general cognitive ability in children: DNA pooling for chromosome 22. American Journal of Medical Genetics 81(6), pp. 486-486.
• Spurlock, G., Williams, N., Williams, H. and Owen, M. 1998. Polymorphism screening of the human type 1 Sigma (σ) receptor (a candidate gene for schizophrenia) using a modified dideoxy fingerprinting technique. American Journal of Medical Genetics - Neuropsychiatric Genetics 81(6), pp. 525-526.
• Deb, S., Braganza, J., Owen, M. J., Kehoe, P., Williams, H. and Norton, N. 1998. No significant association between a PS-1 intronic polymorphism and dementia in Down's syndrome. Alzheimers Reports 1(6), pp. 365-368.
• Murphy, K. C. and Owen, M. J. 1998. Chromosome 22qII deletions and aggressive behaviour. British Journal of Psychiatry 173, pp. 353-354. (10.1192/bjp.173.4.353b)
• Wu, W. S. et al. 1998. Genetic studies on chromosome 12 in late-onset Alzheimer disease. JAMA - The Journal of the American Medical Association 280(7), pp. 619-622. (10.1001/jama.280.7.619)
• Straub, R. E. et al. 1998. A transmission disequilibrium and linkage analysis of D22S278 marker alleles in 574 families: further support for a susceptibility locus for schizophrenia at 22q12. Schizophrenia Collaborative Linkage Group for Chromosome 22. Schizophrenia Research 32(2), pp. 115-121. (10.1016/S0920-9964(98)00048-6)
• Wright, P. et al. 1998. A transmission/disequilibrium study of the DRB1*04 gene locus on chromosome 6p21.3 with schizophrenia. Schizophrenia Research 32(2), pp. 75-80. (10.1016/S0920-9964(98)00050-4)
• Cardno, A. G., Jones, L. A., Murphy, K. C., Sanders, R. D., Asherson, P., Owen, M. J. and McGuffin, P. 1998. Sibling pairs with schizophrenia or schizoaffective disorder: associations of subtypes, symptoms and demographic variables. Psychological Medicine 28(4), pp. 815-823. (10.1017/S0033291798006783)
• Owen, M. J. and Craddock, N. J. 1998. Chromosome 11 workshop. Psychiatric Genetics 8(2), pp. 89-92.
• Owen, M. J. and McGuffin, P. 1998. The programmed alliance of two disciplines. La Recherche 311, pp. 38-39.
• Asherson, P. et al. 1998. A study of chromosome 4p markers and dopamine D5 receptor gene in schizophrenia and bipolar disorder. Molecular Psychiatry 3(4), pp. 310-320. (10.1038/sj.mp.4000399)
• Kirov, G. et al. 1998. Low activity allele of catechol-O-methyltransferase gene associated with rapid cycling bipolar disorder. Molecular Psychiatry 3(4), pp. 342-345. (10.1038/sj.mp.4000385)
• Daniels, J., Holmans, P. A., Williams, N. M., Turic, D., McGuffin, P., Plomin, R. and Owen, M. J. 1998. A simple method for analyzing microsatellite allele image patterns generated from DNA pools and its application to allelic association studies. American Journal of Human Genetics 62(5), pp. 1189-1197. (10.1086/301816)
• Chorney, M. et al. 1998. A Quantitative Trait Locus Associated With Cognitive Ability in Children. Psychological Science 9(3), pp. 159-166. (10.1111/1467-9280.00032)
• Bowen, T. et al. 1998. Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia. Molecular Psychiatry 3(3), pp. 266-269. (10.1038/sj.mp.4000400)
• Daniels, J., McGuffin, P., Owen, M. J. and Plomin, R. 1998. Molecular genetic studies of cognitive ability. Human Biology 70(2), pp. 281-296.
• Williams, J. et al. 1998. A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia. Molecular Psychiatry 3(2), pp. 141-149.
• Spurlock, G. et al. 1998. European Multicentre Association Study of Schizophrenia: a study of the DRD2 Ser311Cys and DRD3 Ser9Gly polymorphisms. American Journal of Medical Genetics 81(1), pp. 24-28. (10.1002/(SICI)1096-8628(19980207)81:1<24::AID-AJMG5>3.0.CO;2-N)
• Cardno, A. G., Murphy, K. C., Jones, L. A., Cobb, A. M., Gray, J., McGuffin, P. and Owen, M. J. 1998. Polydactyly and psychosis. Five cases of co-occurrence. British Journal of Psychiatry 172, pp. 184-185. (10.1192/bjp.172.2.184)
• Murphy, K. C., Jones, R. G., Griffiths, E., Thompson, P. W. and Owen, M. J. 1998. Chromosome 22qII deletions. An under-recognised cause of idiopathic learning disability. British Journal of Psychiatry 172, pp. 180-183. (10.1192/bjp.172.2.180)
• Ball, D. et al. 1998. Dopamine markers and general cognitive ability. NeuroReport 9(2), pp. 347-349. (10.1097/00001756-199801260-00031)
• Arranz, M. J. et al. 1998. Evidence for association between polymorphisms in the promoter and coding regions of the 5-HT2A receptor gene and response to clozapine. Molecular Psychiatry 3(1), pp. 61-66. (10.1038/sj.mp.4000348)
• Owen, M. J. 1998. Psychiatric disorders in Wolfram syndrome heterozygotes. Molecular Psychiatry 3(1), pp. 12-13.
• Murphy, K. C. and Owen, M. J. 1998. The behavioural phenotype in velo-cardio-facial syndrome. Schizophrenia Research 29(1-2), pp. 132-132.
• Murphy, K. C., Williams, N. M., Cardno, A. G., Jones, L. A., Holmans, P. A., McGuffin, P. and Owen, M. J. 1998. A linkage study of chromosome 22q in SIB-pairs with schizophrenia. Schizophrenia Research 29(1-2), pp. 131-132. (10.1016/S0920-9964(97)88632-X)
• Murphy, K. C., Jones, R. G., Griffiths, E., Thompson, P. W. and Owen, M. J. 1998. Chromosome 22q11 deletions - An under-recognized cause of idiopathic learning disability?. Schizophrenia Research 29(1-2), pp. 132-132. (10.1016/S0920-9964(97)88634-3)
• Bowen, T. et al. 1998. Linked polymorphisms upstream of exons 1 and 2 of the human cholecystokinin gene are not associated with schizophrenia or bipolar disorder. Molecular Psychiatry 3(1), pp. 67-71. (10.1038/sj.mp.4000293)
• Spurlock, G. et al. 1998. A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter. Molecular Psychiatry 3(1), pp. 42-49. (10.1038/sj.mp.4000342)
• Cardno, A. G. et al. 1998. Association between functional psychosis and expanded CAG/CTG repeats is not explained by health stratification [comparative study]. Psychiatric Genetics 8(1), pp. 29-32. (10.1097/00041444-199800810-00005)
• Vallada, H. P. et al. 1998. Linkage analysis between bipolar affective disorder and markers on chromosome X. Psychiatric Genetics 8(3), pp. 183-186. (10.1097/00041444-199800830-00008)

1997

• Jones, L. et al. 1997. No evidence for expanded polyglutamine sequences in bipolar disorder and schizophrenia. Molecular Psychiatry 2(6), pp. 478-482. (10.1038/sj.mp.4000297)
• Williams, J., McGuffin, P., Nothen, . and Owen, M. J. 1997. A meta analysis of association between the 5-HT2a receptor, T102C polymorphism and schizophrenia. American Journal of Medical Genetics 74(6), pp. 612-612.
• Murphy, K. C., Jones, R. G., Griffiths, E., Thompson, P. W. and Owen, M. J. 1997. Chromosome 22q11 deletions: An underrecognized cause of idiopathic learning disability?. American Journal of Medical Genetics 74(6), pp. 567-567.
• Murphy, K. C. and Owen, M. J. 1997. The behavioral phenotype in velo-cardio-facial syndrome. American Journal of Medical Genetics 74(6), pp. 660-660.
• Vallada, H. P. et al. 1997. Linkage studies in bipolar affective disorder with markers on chromosome Xq25-27. American Journal of Medical Genetics 74(6), pp. 679-680.
• Craddock, N. J. et al. 1997. Expanded CAG/CTG repeats in bipolar disorder: no correlation with phenotypic measures of illness severity. Biological psychiatry 42(10), pp. 876-881. (10.1016/s0006-3223(96)00516-1)
• Kunugi, H. et al. 1997. Catechol-O-methyltransferase polymorphisms and schizophrenia: a transmission disequilibrium study in multiply affected families. Psychiatric Genetics 7(3), pp. 97-101. (10.1097/00041444-199723000-00001)
• Davies, S. J., Norton, N., Daniels, J. K. and Owen, M. J. 1997. Parietal foramina and multiple exostoses - familial inheritance of a molecular deletion. American Journal of Human Genetics 61(4), pp. A95-A95.
• Owen, M. J. and McGuffin, P. 1997. Genetics and psychiatry. British Journal of Psychiatry 171, pp. 201-202. (10.1192/bjp.171.3.201)
• Rees, M. et al. 1997. Association studies of bipolar disorder at the human serotonin transporter gene (hSERT; 5HTT). Molecular Psychiatry 2(5), pp. 398-402. (10.1038/sj.mp.4000256)
• Guy, C. et al. 1997. Exclusion of expansion of 50 CAG/CTG trinucleotide repeats in bipolar disorder. American Journal of Psychiatry 154(8), pp. 1146-1147.
• Williams, N. M., Cardno, A. G., Murphy, K. C., Jones, L. A., Asherson, P., McGuffin, P. and Owen, M. J. 1997. Association between schizophrenia and a microsatellite polymorphism at the dopamine D5 receptor gene. Psychiatric Genetics 7(2), pp. 83-85. (10.1097/00041444-199722000-00005)
• Owen, M. J., Holmans, P. A. and McGuffin, P. 1997. Association studies in psychiatric genetics. Molecular Psychiatry 2(4), pp. 270-273. (10.1038/sj.mp.4000292)
• Daniels, J. K. et al. 1997. Linkage study of chromosome 6p in sib-pairs with schizophrenia. American Journal of Medical Genetics 74(3), pp. 319-323. (10.1002/(SICI)1096-8628(19970531)74:3<319::AID-AJMG14>3.0.CO;2-R)
• Williams, J., McGuffin, P., Nothen, M. and Owen, M. J. 1997. Meta-analysis of association between the 5-HT2a receptor T102C polymorphism and schizophrenia.. The Lancet 349(9060), pp. 1221. (10.1016/S0140-6736(05)62413-0)
• Speight, G. et al. 1997. Exclusion of CAG/CTG trinucleotide repeat loci which map to chromosome 4 in bipolar disorder and schizophrenia. American Journal of Medical Genetics 74(2), pp. 204-206. (10.1002/(SICI)1096-8628(19970418)74:2<204::AID-AJMG19>3.0.CO;2-M)
• Spurlock, G. et al. 1997. Meta-analysis of association studies between schizophrenia and polymorphisms of the 5-hydroxytryptamine type 2A receptor gene. Schizophrenia Research 24(1-2), pp. 91. (10.1016/S0920-9964(97)82247-5)
• Arranz, M. et al. 1997. Polymorphisms in the 5-HT2A receptor gene and promoter region associated with clozapine response. Schizophrenia Research 24(1-2), pp. 90. (10.1016/S0920-9964(97)82243-8)
• Williams, N. M. et al. 1997. No evidence for an allelic association between schizophrenia and markers D22S278 and D22S283. American Journal of Medical Genetics 74(1), pp. 37-39. (10.1002/(SICI)1096-8628(19970221)74:1<37::AID-AJMG8>3.0.CO;2-S)
• Andrew, M. and Owen, M. J. 1997. Hyperekplexia: abnormal startle response due to glycine receptor mutations. British Journal of Psychiatry 170, pp. 106-108. (10.1192/bjp.170.2.106)
• Petrill, S. A. et al. 1997. No association between general cognitive ability and the A1 allele of the D2 dopamine receptor gene. Behavior Genetics 27(1), pp. 29-31. (10.1023/A:1025659124405)
• Jonsson, E. G. et al. 1997. Tryptophan hydroxylase and catechol-O-methyltransferase gene polymorphisms: relationships to monoamine metabolite concentrations in CSF of healthy volunteers. European Archives of Psychiatry and Clinical Neuroscience 247(6), pp. 297-230. (10.1007/BF02922258)
• Thomas, N. S. T. et al. 1997. Molecular genetic studies in familial Rett syndrome. European Child & Adolescent Psychiatry 6(Supp 1), pp. 94-94.
• Petrill, S. A. et al. 1997. Failure to replicate a QTL association between a DNA marker identified by EST00083 and IQ. Intelligence 25(3), pp. 179-184. (10.1016/S0160-2896(97)90041-6)

1996

• Craddock, N. J., O'Donovan, M. C. and Owen, M. J. 1996. Introducing Selfcite 2.0--career enhancing software. BMJ 313(7072), pp. 1659-1660. (10.1136/bmj.313.7072.1659)
• Cardno, A. G. et al. 1996. Factor analysis of schizophrenic symptoms using the OPCRIT checklist. Schizophrenia Research 22(3), pp. 233-239. (10.1016/S0920-9964(96)00060-6)
• Craddock, N. J. and Owen, M. J. 1996. Candidate gene association studies in psychiatric genetics: a SERTain future?. Molecular Psychiatry 1(6), pp. 434-436.
• Cardno, A. G. et al. 1996. Expanded CAG/CTG repeats in schizophrenia. A study of clinical correlates. British Journal of Psychiatry 169(6), pp. 766-771. (10.1192/bjp.169.6.766)
• O'Donovan, M. C., Craddock, N. J., Guy, C., McGuffin, P. and Owen, M. J. 1996. Involvement of expanded trinucleotide repeats in common diseases. The Lancet 348(9043), pp. 1739-1740. (10.1016/s0140-6736(05)65870-9)
• Vallada, H. et al. 1996. Linkage studies in bipolar affective disorder with markers on chromosome 21. Journal of affective disorders 41(3), pp. 217-221. (10.1016/s0165-0327(96)00055-9)
• O'Donovan, M. C. et al. 1996. Confirmation of association between expanded CAG/CTG repeats and both schizophrenia and bipolar disorder. Psychological Medicine -London- 26(6), pp. 1145-1153. (10.1017/s0033291700035868)
• Levinson, D. F. et al. 1996. Additional support for schizophrenia linkage on chromosomes 6 and 8: a multicenter study. Schizophrenia Linkage Collaborative Group for Chromosomes 3, 6 and 8. American Journal of Medical Genetics 67(6), pp. 580-594. (10.1002/(SICI)1096-8628(19961122)67:6<580::AID-AJMG11>3.0.CO;2-P)
• Petrill, S. A. et al. 1996. DNA markers associated with general and specific cognitive abilities. Intelligence 23(3), pp. 191. (10.1016/S0160-2896(96)90003-3)
• Kunugi, H. et al. 1996. A linkage study of schizophrenia with DNA markers from chromosome 8p21-p22 in 25 multiplex families. Schizophrenia Research 22(1), pp. 61-68. (10.1016/0920-9964(96)00048-5)
• Daniels, J., McGuffin, P. and Owen, M. J. 1996. Molecular genetic research on IQ: can it be done? Should it be done?. Journal of Biosocial Science 28(4), pp. 491-507. (10.1017/S0021932000022550)
• Bowen, T. et al. 1996. Expansion of 50 CAG/CTG repeats excluded in schizophrenia by application of a highly efficient approach using repeat expansion detection and a PCR screening set. American Journal of Human Genetics 59(4), pp. 912-917.
• Kehoe, P. et al. 1996. Association between a PS-1 intronic polymorphism and late onset Alzheimer's disease. NeuroReport 7(13), pp. 2155-2158. (10.1097/00001756-199609020-00019)
• Owen, M. J., Kehoe, P. and Williams, J. 1996. Presenilin-1 polymorphism and Alzheimer's disease. The Lancet 348(9024), pp. 414. (10.1016/S0140-6736(05)65041-6)
• Farmer, A. and Owen, M. J. 1996. Genomics: the next psychiatric revolution?. British Journal of Psychiatry 169(2), pp. 135-138. (10.1192/bjp.169.2.135)
• Ashworth, A. et al. 1996. Linkage analysis of the fragile X gene FMR-1 and schizophrenia: no evidence for linkage but report of a family with schizophrenia and an unstable triplet repeat. Psychiatric Genetics 6(2), pp. 81-86. (10.1097/00041444-199622000-00008)
• Parfitt, E. et al. 1996. No evidence for linkage between schizophrenia and eight microsatellite markers on chromosome 19. Human Heredity 46(4), pp. 191-196. (10.1159/000154352)
• Craddock, N. J., Asherson, P., Owen, M. J., Williams, J., McGuffin, P. and Farmer, A. E. 1996. Concurrent validity of the OPCRIT diagnostic system. Comparison of OPCRIT diagnoses with consensus best-estimate lifetime diagnoses. British Journal of Psychiatry 169(1), pp. 58-63. (10.1192/bjp.169.1.58)
• Craddock, N. J. and Owen, M. J. 1996. Modern molecular genetic approaches to psychiatric disease. British Medical Bulletin 52(3), pp. 434-452. (10.1093/oxfordjournals.bmb.a011558)
• Williams, J. et al. 1996. Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene. European Multicentre Association Study of Schizophrenia (EMASS) Group. The Lancet 347(9011), pp. 1294-1296. (10.1016/S0140-6736(96)90939-3)
• Asherson, P. et al. 1996. Linkage, association and mutational analysis of the dopamine D3 receptor gene in schizophrenia. Molecular Psychiatry 1(2), pp. 125-132.
• Kehoe, P., Williams, J., Lovestone, S., Wilcock, G. and Owen, M. J. 1996. Presenilin-1 polymorphism and Alzheimer's disease. The UK Alzheimer's Disease Collaborative Group. The Lancet 347(9009), pp. 1185.
• Murphy, K. C. and Owen, M. J. 1996. Schizophrenia, CATCH 22 and FISH. British Journal of Psychiatry 168(4), pp. 397-398.
• Craddock, N. J., Daniels, J., Holmans, P. A., Williams, N. M. and Owen, M. J. 1996. Increasing the efficiency of genomic searches for linkage in complex disorders by DNA pooling of affected sib-pairs. Molecular Psychiatry 1(1), pp. 59-64.
• Owen, M. J. and Craddock, N. J. 1996. Modern molecular genetic approaches to complex traits: implications for psychiatric disorders [review]. Molecular Psychiatry 1(1), pp. 21-26.
• Lim, L. C. C. et al. 1996. Assessing the statistical power to detect linkage in a sample of 51 bipolar affective disorder pedigrees. Behavior Genetics 26(2), pp. 113-122. (10.1007/bf02359889)
• Gill, M. et al. 1996. A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22).. American Journal of Medical Genetics 67(1), pp. 40-45. (10.1002/(SICI)1096-8628(19960216)67:1<40::AID-AJMG6>3.0.CO;2-W)
• Cardno, A., Holmans, P. A., Harvey, I., Williams, M. B., Owen, M. J. and McGuffin, P. 1996. Factor-derived subsyndromes of schizophrenia and familial morbid risks. Schizophrenia Research 18(2-3), pp. IVA2-IVA2.
• Murphy, K. C. and Owen, M. J. 1996. Minor physical anomalies and their relationship to the aetiology of schizophrenia. British Journal of Psychiatry 168(2), pp. 139-142. (10.1192/bjp.168.2.139)
• Daniels, J. K. et al. 1996. No evidence for allelic association between schizophrenia and a polymorphism determining high or low catechol O-methyltransferase activity. American Journal of Psychiatry 153(2), pp. 268-270. (10.1176/ajp.153.2.268)
• O'Donovan, M. C. and Owen, M. J. 1996. Dynamic mutations and psychiatric genetics. Psychological Medicine 26(1), pp. 1-6. (10.1017/S0033291700033663)
• Lin, M. W. et al. 1996. Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1-q32. Cytogenetics and Cell Genetics 75, pp. 2-3.
• Jacobsen, N. et al. 1996. Association study of bipolar disorder at the phospholipase A2 gene (PLA2A) in the Darier's disease (DAR) region of chromosome 12q23-q24.1. Psychiatric Genetics 6(4), pp. 195-199. (10.1097/00041444-199624000-00005)

1995

• Roberts, A. G. et al. 1995. Partial characterization and assignment of the gene for protoporphyrinogen oxidase and variegate porphyria to human chromosome 1q23. Human Molecular Genetics 4(12), pp. 2387-2390. (10.1093/hmg/4.12.2387)
• Arranz, M. et al. 1995. Schizophrenia and the androgen receptor gene: report of a sibship showing co-segregation with Reifenstein syndrome but no evidence for linkage in 23 multiply affected families. American Journal of Medical Genetics 60(5), pp. 377-381. (10.1002/ajmg.1320600506)
• Dawson, E. et al. 1995. Systematic search for major genes in schizophrenia: methodological issues and results from chromosome 12. American Journal of Medical Genetics 60(5), pp. 424-433. (10.1002/ajmg.1320600513)
• Okoro, C. et al. 1995. No evidence for linkage between the X-chromosome marker DXS7 and schizophrenia. American Journal of Medical Genetics 60(5), pp. 461-464. (10.1002/ajmg.1320600520)
• Lin, M. W. et al. 1995. Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1-q32. Psychiatric Genetics 5(3), pp. 117-126. (10.1097/00041444-199505030-00004)
• Vallada, H. et al. 1995. Chromosome 22 markers demonstrate transmission disequilibrium with schizophrenia. Psychiatric Genetics 5(3), pp. 127-130. (10.1097/00041444-199505030-00005)
• McGuffin, P., Owen, M. J. and Farmer, A. E. 1995. Genetic basis of schizophrenia. The Lancet 346(8976), pp. 678-682. (10.1016/S0140-6736(95)92285-7)
• Craddock, N. J., Daniels, J., Roberts, E., Rees, M., McGuffin, P. and Owen, M. J. 1995. No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms. American Journal of Medical Genetics 60(4), pp. 322-324. (10.1002/ajmg.1320600412)
• O'Donovan, M. C. et al. 1995. Expanded CAG repeats in schizophrenia and bipolar disorder [letter]. Nature Genetics 10(4), pp. 380-381. (10.1038/ng0895-380)
• Skuder, P. et al. 1995. A polymorphism in mitochondrial DNA associated with IQ?. Intelligence 21(1), pp. 1-11. (10.1016/0160-2896(95)90035-7)
• Liddell, M. B., Bayer, A. J. and Owen, M. J. 1995. No evidence that common allelic variation in the Amyloid Precursor Protein (APP) gene confers susceptibility to Alzheimer's disease. Human Molecular Genetics 4(5), pp. 853-858. (10.1093/hmg/4.5.853)
• Vallada, H. P. et al. 1995. Linkage studies on chromosome 22 in familial schizophrenia. American Journal of Medical Genetics 60(2), pp. 139-146. (10.1002/ajmg.1320600210)
• Dawson, E. et al. 1995. Linkage studies of bipolar disorder in the region of the Darier's disease gene on chromosome 12q23-24.1. American Journal of Medical Genetics 60(2), pp. 94-102. (10.1002/ajmg.1320600203)
• Mullan, M. et al. 1995. Clinical features of early onset, familial Alzheimer's disease linked to chromosome 14. American Journal of Medical Genetics 60(1), pp. 44-52. (10.1002/ajmg.1320600109)
• Daniels, J., Williams, J., Asherson, P., McGuffin, P. and Owen, M. J. 1995. No association between schizophrenia and polymorphisms within the genes for debrisoquine 4-hydroxylase (CYP2D6) and the dopamine transporter (DAT).. American Journal of Medical Genetics 60(1), pp. 85-87. (10.1002/ajmg.1320600115)
• Plomin, R. et al. 1995. Allelic associations between 100 DNA markers and high versus low IQ. Intelligence 21(1), pp. 31. (10.1016/0160-2896(95)90037-3)
• Craddock, N. J., Roberts, Q., Williams, N. M., McGuffin, P. and Owen, M. . J. 1995. Association study of bipolar disorder using a functional polymorphism (Ser311-->Cys) in the dopamine D2 receptor gene. Psychiatric Genetics 5(2), pp. 63-65.

1994

• Rees, M. I., Andrew, M., Jawad, S. and Owen, M. J. 1994. Evidence for recessive as well as dominant forms of startle disease (hyperekplexia) caused by mutations in the alpha 1 subunit of the inhibitory glycine receptor. Human Molecular Genetics 3(12), pp. 2175-2179. (10.1093/hmg/3.12.2175)
• Craddock, N. J. and Owen, M. J. 1994. Is there an inverse relationship between Down's syndrome and bipolar affective disorder? literature review and genetic implications [Review]. Journal of Intellectual Disability Research 38(6), pp. 613-620. (10.1111/j.1365-2788.1994.tb00462.x)
• McGuffin, P., Owen, M. J., Asherson, P. and Farmer, A. E. 1994. Genetics, chance and dysmorphogenesis in schizophrenia. British Journal of Psychiatry 165, pp. 694-695. (10.1192/bjp.165.5.693b)
• Daniels, J., Williams, J., Mant, R., Asherson, P., McGuffin, P. and Owen, M. J. 1994. Repeat length variation in the dopamine D4 receptor gene shows no evidence of association with schizophrenia. American Journal of Medical Genetics 54(3), pp. 256-258. (10.1002/ajmg.1320540313)
• Craddock, N. J., McGuffin, P. and Owen, M. J. 1994. Darier's disease cosegregating with affective disorder [letter]. British Journal of Psychiatry 165(2), pp. 272-272. (10.1192/bjp.165.2.272a)
• Plomin, R., Owen, M. J. and McGuffin, P. 1994. The genetic basis of complex human behaviors. Science 264(5166), pp. 1733-1739. (10.1126/science.8209254)
• Craddock, N. J., Daniels, J., McGuffin, P. and Owen, M. J. 1994. Variation at the fragile X locus does not influence susceptibility to bipolar disorder. American Journal of Medical Genetics 54(2), pp. 141-143. (10.1002/ajmg.1320540209)
• Thapar, A., Gottesman, I. I., Owen, M. J., O'Donovan, M. C. and McGuffin, P. 1994. The genetics of mental retardation. The British Journal of Psychiatry 164(6), pp. 747. (10.1192/bjp.164.6.747)
• James, C. M., Daniels, J., Wiles, C. M. and Owen, M. J. 1994. Debrisoquine hydroxylase gene polymorphism in motor-neuron disease. Neurodegeneration 3(2), pp. 149-152.
• McGuffin, P., Asherson, P., Owen, M. J. and Farmer, A. 1994. The strength of the genetic effect. Is there room for an environmental influence in the aetiology of schizophrenia?. British Journal of Psychiatry 164(5), pp. 593-599. (10.1192/bjp.164.5.593)
• Asherson, P. et al. 1994. Imprinting and anticipation. Are they relevant to genetic studies of schizophrenia?. The British Journal of Psychiatry 164(5), pp. 619-624. (10.1192/bjp.164.5.619)
• Craddock, N. J. and Owen, M. J. 1994. Chromosomal aberrations and bipolar affective disorder [review]. British Journal of Psychiatry 164(4), pp. 507-512. (10.1192/bjp.164.4.507)
• Asherson, P., Williams, N. M., Roberts, E., McGuffin, M. and Owen, M. J. 1994. DRD2 Ser311/Cys311 polymorphism in schizophrenia. The Lancet 343(8904), pp. 1045-1045.
• Craddock, N. J., Brockington, I., Mant, R., Parfitt, E., McGuffin, P. and Owen, M. J. 1994. Bipolar affective puerperal psychosis associated with consanguinity. British Journal of Psychiatry 164(3), pp. 359-364. (10.1192/bjp.164.3.359)
• Craddock, N. J., Owen, M. J., Burge, S., Kurian, B., Thomas, P. and McGuffin, P. 1994. Familial cosegregation of major affective disorder and Darier's disease (keratosis follicularis). British Journal of Psychiatry 164(3), pp. 355-358. (10.1192/bjp.164.3.355)
• Pulver, A. E. et al. 1994. Follow-up of a report of a potential linkage for schizophrenia on chromosome 22q12-q13.1: Part 2. American Journal of Medical Genetics 54(1), pp. 44-50. (10.1002/ajmg.1320540109)
• Shaikh, S. et al. 1994. Failure to find linkage between a functional polymorphism in the dopamine D4 receptor gene and schizophrenia. American Journal of Medical Genetics 54(1), pp. 8-11. (10.1002/ajmg.1320540104)
• Mant, R., Williams, J., Asherson, P., Parfitt, E., McGuffin, P. and Owen, M. J. 1994. Relationship between homozygosity at the dopamine D3 receptor gene and schizophrenia. American Journal of Medical Genetics 54(1), pp. 21-26. (10.1002/ajmg.1320540106)
• Owen, M. J., Liddell, M. and McGuffin, P. 1994. Alzheimer's disease. British Medical Journal (BMJ) 308(6930), pp. 672-673. (10.1136/bmj.308.6930.672)
• Plomin, R. et al. 1994. DNA markers associated with high versus low IQ: The IQ quantitative trait loci (QTL) project. Behavior Genetics 24(2), pp. 107-118. (10.1007/BF01067815)
• Liddell, M. B., Williams, J., Bayer, A. J., Kaiser, F. and Owen, M. J. 1994. Confirmation of association between the e4 allele of apolipoprotein E and Alzheimer's disease. Journal of Medical Genetics 31(3), pp. 197-200. (10.1136/jmg.31.3.197)
• Asherson, P. and Owen, M. J. 1994. Anticipation in mental illness. The American Journal of Human Genetics 54(2), pp. 386-387.
• Parfitt, E. et al. 1994. The gene for Darier's disease maps between D12S78 and D12S79. Human Molecular Genetics 3(1), pp. 35-38. (10.1093/hmg/3.1.35)
• Vallada, H., Gill, M., Nanko, S., Owen, M. J., Murray, R. and Collier, C. 1994. Is there a major gene for schizophrenia on chromosome-22. Schizophrenia Research 11(2), pp. 147-147.
• Korner, J. et al. 1994. Association and haplotype analysis at the tyrosine hydroxylase locus in a combined German-British sample of manic depressive patients and controls. Psychiatric Genetics 4(3), pp. 167-175. (10.1097/00041444-199400430-00007)
• Owen, M. J. 1994. The molecular genetics of Alzheimer's disease. Molecular and Cell Biology of Human Diseases Series 1994(4), pp. 92-109.
• McGuffin, P., Owen, M. J., O'Donovan, M. C., Thapar, A. and Gottesman, I. I. 1994. Seminars in psychiatric genetics. Gaskell, Royal College of Psychiatrists.
• Daniels, J. et al. 1994. IQ and variation in the number of fragile X CGG repeats: No association in a normal sample. Intelligence 19(1), pp. 45-50. (10.1016/0160-2896(94)90052-3)

1993

• Craddock, N. J. et al. 1993. The gene for Darier's disease maps to chromosome 12q23-q24.1. Human Molecular Genetics 2(11), pp. 1941-1943. (10.1093/hmg/2.11.1941)
• McGuffin, P. and Owen, M. J. 1993. Molecular-genetics and schizophrenia - the current picture. Behavior Genetics 23(6), pp. 558-558.
• Saudino, K. J. et al. 1993. Applying a QTL association approach to temperament. Behavior Genetics 23(6), pp. 564-564.
• Asherson, P. et al. 1993. Failure to find linkage between schizophrenia and genetic markers on chromosome 21. American Journal of Medical Genetics 48(3), pp. 161-165. (10.1002/ajmg.1320480310)
• Mant, R., Williams, J., Asherson, P., Parfitt, E., McGuffin, P. and Owen, M. J. 1993. Susceptibility to schizophrenia and the dopamine d3 receptor gene. American Journal of Human Genetics 53(3), pp. 1654-1654.
• Owen, M. J. and McGuffin, P. 1993. Association and linkage: complementary strategies for complex disorders.. Journal of Medical Genetics 30(8), pp. 638-639. (10.1136/jmg.30.8.638)
• Shaikh, S. et al. 1993. The dopamine D3 receptor gene: no association with bipolar affective disorder. Journal of Medical Genetics 30(4), pp. 308-309. (10.1136/jmg.30.4.308)
• Gill, M. et al. 1993. A linkage study of schizophrenia with DNA markers from the long arm of chromosome 11. Psychological Medicine 23(1), pp. 27-44. (10.1017/S0033291700038824)
• Jones, P. B., Owen, M. J., Lewis, S. W. and Murray, R. M. 1993. A case-control study of family history and cerebral cortical abnormalities in schizophrenia. Acta Psychiatrica Scandinavica 87(1), pp. 6-12. (10.1111/j.1600-0447.1993.tb03322.x)
• Craddock, N. J., Burge, S., Parfitt, L. and Owen, M. J. 1993. Linkage is excluded between Darier's disease and the Duffy blood group locus in five British families. Annales de Genetique 36(4), pp. 211-213.

1992

• Owen, M. J. and Liddell, M. 1992. Role of amyloid beta-protein in Alzheimer's disease. The Lancet 340(8823), pp. 851-851.
• Owen, M. J. and McGuffin, P. 1992. The molecular genetics of schizophrenia.. British Medical Journal (BMJ) 305(6855), pp. 664-665. (10.1136/bmj.305.6855.664)
• Mant, R., Asherson, P., Gill, M., McGuffin, P. and Owen, M. J. 1992. Schizophrenia scepticism. Nature Genetics 2(1), pp. 12-12. (10.1038/ng0992-12)
• Owen, M. J. et al. 1992. No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia. Human Genetics 90(1-2), pp. 131-132. (10.1007/BF00210756)
• Vallada, H., Collier, D., Dawson, E., Owen, M. J., Nanko, S., Murray, R. and Gill, M. 1992. Debrisoquine 4-hydroxylase (CYP2D) locus and possible susceptibility to schizophrenia. The Lancet 340(8812), pp. 181-182. (10.1016/0140-6736(92)93266-P)
• Asherson, P. et al. 1992. No evidence for a pseudoautosomal locus for schizophrenia. Linkage analysis of multiply affected families. British Journal of Psychiatry 161(1), pp. 63-68. (10.1192/bjp.161.1.63)
• O'Donovan, M. C. and Owen, M. J. 1992. Advances and Retreats in the Molecular Genetics of Major Mental Illness. Annals of Medicine 24(3), pp. 171-177. (10.3109/07853899209147816)
• Craddock, N. J. and Owen, M. J. 1992. Christmas disease and major affective disorder [letter]. British Journal of Psychiatry 160, pp. 715-715. (10.1192/bjp.160.5.715a)
• Nanko, S., Gill, M., Owen, M. J., Takazawa, N., Moridaira, J. and Kazamatsuri, H. 1992. Linkage Study of Schizophrenia with Markers on Chromosome 11 in Two Japanese Pedigrees. Psychiatry and Clinical Neurosciences 46(1), pp. 155-159. (10.1111/j.1440-1819.1992.tb00828.x)
• Shaikh, S., Owen, M. J. and Gill, M. 1992. DRD2 (TGn) repeat polymorphism in a large family data set. Schizophrenia Research 6(2), pp. 91-91. (10.1016/0920-9964(92)90088-M)
• Dawson, E. et al. 1992. Genetic linkage analysis of schizophrenia using microsatellite repeat polymorphisms on chromosome 12. Schizophrenia Research 6(2), pp. 90-90. (10.1016/0920-9964(92)90086-K)
• Collier, D., Gill, M., Nanko, S., Owen, M. J. and Vallada, H. 1992. Linkage analysis of schizophrenia on chromosome 22. Schizophrenia Research 6(2), pp. 89-90. (10.1016/0920-9964(92)90085-J)
• Owen, M. J. and GILL, M. 1992. Looking for genes in schizophrenia. Clinical Neuropharmacology 15(Suppl1), pp. 222A-223A. (10.1097/00002826-199201001-00116)

1991

• Upadhyaya, M., Lunt, P. W., Sarfarazi, M., Broadhead, W., Daniels, J., Owen, M. J. and Harper, P. S. 1991. A closely linked DNA marker for facioscapulohumeral disease on chromosome 4q.. Journal of Medical Genetics 28(10), pp. 665-671. (10.1136/jmg.28.10.665)
• Owen, M. J. et al. 1991. Linkage studies of schizophrenia with markers of chromosome-11q. American Journal of Human Genetics 49(4), pp. 354-354.
• Mant, R., Parfitt, E., Hardy, J. and Owen, M. J. 1991. Mononucleotide repeat polymorphism in the APP gene. Nucleic Acids Research 19(16), pp. 4572-4572. (10.1093/nar/19.16.4572-a)
• Owen, M. J., Goate, A. and Hardy, J. 1991. A polymorphic microsatellite repeat sequence on chromosome 21 (D21S80). Nucleic Acids Research 19(16), pp. 4574-4571. (10.1093/nar/19.16.4574)
• Foerster, A., Lewis, S. W., Owen, M. J. and Murray, R. M. 1991. Low birth weight and a family history of schizophrenia predict poor premorbid functioning in psychosis. Schizophrenia Research 5(1), pp. 13-20. (10.1016/0920-9964(91)90049-W)
• Goate, A. et al. 1991. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349(6311), pp. 704-706. (10.1038/349704a0)
• Foerster, A., Lewis, S., Owen, M. J. and Murray, R. 1991. Pre-morbid adjustment and personality in psychosis. Effects of sex and diagnosis. British Journal of Psychiatry 158(2), pp. 171-176. (10.1192/bjp.158.2.171)
• Owen, M. J. and McGuffin, P. 1991. DNA-and classical genetic markers in schizophrenia. European Archives of Psychiatry and Clinical Neuroscience 240(3), pp. 197-203. (10.1007/BF02190764)
• McGuffin, P. and Owen, M. J. 1991. The molecular genetics of schizophrenia: An overview and forward view. European Archives of Psychiatry and Clinical Neuroscience 240(3), pp. 169-173. (10.1007/BF02190759)
• Mant, R. et al. 1991. Exclusion of close linkage between GABA a receptor subunit 1a gene and schizophrenia using a microsatellite repeat marker. Cytogenetics and Cell Genetics 58(3-4), pp. 1900-1991.

1990

• Upadhyaya, M., Lunt, P., Sarfarazi, M., Broadhead, W., Daniels, J., Owen, M. J. and Harper, P. 1990. DNA marker applicable to presymptomatic and prenatal diagnosis of facioscapulohumeral disease. The Lancet 336(8726), pp. 1320-1321. (10.1016/0140-6736(90)93005-A)
• St George-Hyslop, P. H. et al. 1990. Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder. Nature 347(6289), pp. 194-197. (10.1038/347194a0)
• Owen, M. J., McGuffin, P. and Andrews, R. 1990. Obstetric complications and schizophrenia. The Lancet 336(8707), pp. 122-122. (10.1016/0140-6736(90)91643-O)
• Owen, M. J., Craufurd, D. and St Clair, D. 1990. Localisation of a susceptibility locus for schizophrenia on chromosome 5. British Journal of Psychiatry 157(1), pp. 123-127. (10.1192/bjp.157.1.123)
• Owen, M. J., James, L., Hardy, J., Williamson, R. and Goate, A. 1990. Physical mapping around the Alzheimer disease locus on the proximal long arm of chromosome 21.. American Journal of Human Genetics 46(2), pp. 316-322.
• Owen, M. J. and Mullan, M. J. 1990. Molecular genetic studies of manic-depression and schizophrenia. Trends in Neurosciences 13(1), pp. 29-31. (10.1016/0166-2236(90)90059-J)
• Goate, A. et al. 1990. Genetics of Alzheimer's disease. Advances in Neurology -New York- Raven Press- 51, pp. 197-198.

1989

• Hardy, J., Goate, A., Owen, M. J. and Rossor, M. 1989. Presenile dementia associated with mosaic trisomy 21 in a patient with a down syndrome child. The Lancet 334(8665), pp. 743-743. (10.1016/S0140-6736(89)90805-2)
• Hardy, J., Goate, A., Owen, M. J., Mullan, M., Rossor, M. and Pearson, R. 1989. Modelling the occurrence and pathology of Alzheimer's disease. Neurobiology of Aging 10(5), pp. 429-431. (10.1016/0197-4580(89)90084-5)
• Owen, M. J., Lewis, S. W. and Murray, R. M. 1989. Family history and cerebral ventricular enlargement in schizophrenia. A case control study. British Journal of Psychiatry 154(5), pp. 629-634. (10.1192/bjp.154.5.629)
• Goate, A. et al. 1989. Predisposing locus for Alzheimer's disease on chromosome 21. The Lancet 333(8634), pp. 352-355. (10.1016/S0140-6736(89)91725-X)
• HARDY, J. A. et al. 1989. Molecular genetics of Alzheimer's disease. Biochemical Society Transactions 17(1), pp. 75-76. (10.1042/bst0170075)

1988

• Owen, M. J. and Murray, R. 1988. Blue genes. British Medical Journal (BMJ) 297(6653), pp. 871-872.
• Owen, M. J. and Lewis, S. W. 1988. Risk factors in schizophrenia. British Journal of Psychiatry 153(3), pp. 407-407. (10.1192/bjp.153.3.407a)
• Owen, M. J. and Whatley, S. 1988. Polymorphic DNA markers and mental disease. Psychological Medicine 18(3), pp. 529-533.
• Owen, M. J., Lewis, S. W. and Murray, R. M. 1988. Obstetric complications and schizophrenia: a computed tomographic study. Psychological Medicine 18(2), pp. 331-339. (10.1017/S003329170000787X)

1987

• Owen, M. J. and Nimgaonkar, V. 1987. The continuum of psychosis and the gene. British Journal of Psychiatry 150, pp. 566-567.

1986

• Owen, M. J. and Lweis, S. 1986. Lateral ventricular size in schizophrenia. The Lancet 2(8500), pp. 223-224.

1984

• Owen, M. J. and Butler, S. 1984. Does amnesia after transection of the fornix in monkeys reflect abnormal sensitivity to proactive interference?. Behavioural Brain Research 14(3), pp. 183-192.
• Gaffan, D., Saunders, R., Gaffan, E., Harrison, S., Shields, C. and Owen, M. J. 1984. Effects of fornix transection upon associative memory in monkeys: role of the hippocampus in learned action. Quarterly Journal of Experimental Psychology 36(3), pp. 173-221.

1981

• Owen, M. J. and Butler, S. 1981. Amnesia after transection of the fornix in monkeys: Long-term memory impaired, short-term memory intact. Behavioural Brain Research 3(1), pp. 115-123. (10.1016/0166-4328(81)90032-2)

1980

• Owen, M. J. and Butler, S. 1980. Effects of fornix lesions on recognition memory in the monkey. Journal of Anatomy 131(DEC), pp. 771-771.
• Owen, M. J. and Butler, S. 1980. The effects of fornix lesions on latent learning in the rat. Physiology & Behavior 24(5), pp. 817-822. (10.1016/0031-9384(80)90133-X)