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Dr Catharine Porter
Research Associate - Statistics
- PorterC3@cardiff.ac.uk
- Neuadd Meirionnydd, Room 514, University Hospital of Wales, Heath Park, Cardiff, CF14 4YS
Overview
I am a Research Associate in Statistics in the Centre for Trials Research at Cardiff University where I have worked since September 2014. My main areas of interest are solid tumour and haematology trials. I have previously worked for many years as a Data Manager in Clinical Haematology and have extensive experience of Haematology Clinical trials.
I am a PhD in Biochemistry (University of Birmingham) and Master in Public Health (Cardiff University).
Publication
2022
- Fennell, D. A. et al. 2022. Olaparib maintenance versus placebo monotherapy in patients with advanced non-small cell lung cancer (PIN): A multicentre, randomised, controlled, phase 2 trial. EClinicalMedicine 52, article number: 101595. (10.1016/j.eclinm.2022.101595)
- Fennell, D. A. et al. 2022. Active symptom control with or without oral vinorelbine in patients with relapsed malignant pleural mesothelioma (VIM): A randomised, phase 2 trial. eClinicalMedicine 48, article number: 101432. (10.1016/j.eclinm.2022.101432)
2021
- Byrne, A., Adamson, D., Porter, C. and Hurt, C. 2021. Stent insertion for incurable oesophageal carcinoma: what is the optimal treatment? - authors' reply. The Lancet Gastroenterology & Hepatology 6(7), article number: 525. (10.1016/S2468-1253(21)00174-6)
- Adamson, D. et al. 2021. Palliative radiotherapy combined with stent insertion to reduce recurrent dysphagia in oesophageal cancer patients: the ROCS RCT. Health Technology Assessment 25(31) (10.3310/hta25310)
- Adamson, D. et al. 2021. Palliative radiotherapy after oesophageal cancer stenting (ROCS): a multicentre, open-label, phase 3 randomised controlled trial. Lancet Gastroenterology and Hepatology 6(4), pp. 292-303. (10.1016/S2468-1253(21)00004-2)
2020
- Byrne, A. T. et al. 2020. Radiotherapy after esophageal cancer stenting (ROCS): A pragmatic randomized controlled trial evaluating the role of palliative radiotherapy in maintaining swallow.. Journal of Clinical Oncology 38(15_sup), article number: 4569. (10.1200/JCO.2020.38.15_suppl.4569)
2019
- Hurt, C. et al. 2019. Feasibility and economic assessment of chromocolonoscopy for detection of proximal serrated neoplasia within a population-based colorectal cancer screening programme (CONSCOP): an open-label, randomised controlled non-inferiority trial. Lancet Gastroenterology and Hepatology 4(5), pp. 364-375. (10.1016/S2468-1253(19)30035-4)
2018
- Prout, H. C. et al. 2018. Patient understanding and acceptability of an early lung cancer diagnosis trial: a qualitative study. Trials 19, article number: 419. (10.1186/s13063-018-2803-4)
2017
- Neal, R. D. et al. 2017. Immediate chest X-ray for patients at risk of lung cancer presenting in primary care: randomised controlled feasibility trial. British Journal of Cancer 116(3), pp. 293-302. (10.1038/bjc.2016.414)
Articles
- Fennell, D. A. et al. 2022. Olaparib maintenance versus placebo monotherapy in patients with advanced non-small cell lung cancer (PIN): A multicentre, randomised, controlled, phase 2 trial. EClinicalMedicine 52, article number: 101595. (10.1016/j.eclinm.2022.101595)
- Fennell, D. A. et al. 2022. Active symptom control with or without oral vinorelbine in patients with relapsed malignant pleural mesothelioma (VIM): A randomised, phase 2 trial. eClinicalMedicine 48, article number: 101432. (10.1016/j.eclinm.2022.101432)
- Byrne, A., Adamson, D., Porter, C. and Hurt, C. 2021. Stent insertion for incurable oesophageal carcinoma: what is the optimal treatment? - authors' reply. The Lancet Gastroenterology & Hepatology 6(7), article number: 525. (10.1016/S2468-1253(21)00174-6)
- Adamson, D. et al. 2021. Palliative radiotherapy combined with stent insertion to reduce recurrent dysphagia in oesophageal cancer patients: the ROCS RCT. Health Technology Assessment 25(31) (10.3310/hta25310)
- Adamson, D. et al. 2021. Palliative radiotherapy after oesophageal cancer stenting (ROCS): a multicentre, open-label, phase 3 randomised controlled trial. Lancet Gastroenterology and Hepatology 6(4), pp. 292-303. (10.1016/S2468-1253(21)00004-2)
- Byrne, A. T. et al. 2020. Radiotherapy after esophageal cancer stenting (ROCS): A pragmatic randomized controlled trial evaluating the role of palliative radiotherapy in maintaining swallow.. Journal of Clinical Oncology 38(15_sup), article number: 4569. (10.1200/JCO.2020.38.15_suppl.4569)
- Hurt, C. et al. 2019. Feasibility and economic assessment of chromocolonoscopy for detection of proximal serrated neoplasia within a population-based colorectal cancer screening programme (CONSCOP): an open-label, randomised controlled non-inferiority trial. Lancet Gastroenterology and Hepatology 4(5), pp. 364-375. (10.1016/S2468-1253(19)30035-4)
- Prout, H. C. et al. 2018. Patient understanding and acceptability of an early lung cancer diagnosis trial: a qualitative study. Trials 19, article number: 419. (10.1186/s13063-018-2803-4)
- Neal, R. D. et al. 2017. Immediate chest X-ray for patients at risk of lung cancer presenting in primary care: randomised controlled feasibility trial. British Journal of Cancer 116(3), pp. 293-302. (10.1038/bjc.2016.414)
Research
My research interests are clinical trials in oncology, both solid tumours and haematology.
As a trial statistician I am involved in clinical trials from trial design through to final analysis and publication, producing interim analysis for data monitoring committees and central monitoring of data.
I am currently working on Phase 1-3 trials in acute lymphoblastic leukaemia, anal cancer, pleural mesothelioma, lung cancer, oesophageal cancer and endometrial cancer.
I am also involved as an Independent member on Data Monitoring Committees.
Biography
Education and Qualifications
- 2014: Masters In Public Health, Cardiff University, UK
- 1989: PhD (Biochemistry), Birmingham University, UK
- 1985: BSc (Hons) Biological Sciences, University of East Anglia
Career overview
- January 2019 to present: Research Associate (Statistics), Centre for Trials Research, Cardiff University
- October 2017-January 2019: Acting Research Associate (Statistics), Centre for Trials Research, Cardiff University
- 2014-October 2017: Research Assistant (Statistics), Wales Cancer Trials Unit, Cardiff University
- 2001-2005: Data Coordinator, Clinical Haematology and Bone Marrow Transplant Unit, University Hospital Birmingham
- 1998-2001: Data Manager, Clinical Haematology and Bone Marrow Transplant Unit, Birmingham Heartlands Hospital
Academic positions
- 1989-1993: Post-doctoral Research Fellow, School of Biological Sciences, Birmingham University