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Majd Protty MBChB (Hons), PgDip, MSc, PhD, MRCP (UK), MAcadMEd, FRCP, FESC, FACC

Dr Majd Protty

MBChB (Hons), PgDip, MSc, PhD, MRCP (UK), MAcadMEd, FRCP, FESC, FACC

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Available for postgraduate supervision

Teams and roles for Majd Protty

Overview

Dr Protty is an interventional cardiologist with research interests in inflammation (bodily reaction to damaging irritants), thrombosis and haemostasis (clot formation in health and disease), as it relates to patients suffering from heart conditions.

He completed his PhD at the Cardiff Lipidomics Group in 2021, funded by the Wellcome Trust GW4CAT fellowship. Following this, He was awarded a Starter Grant for Clinical Lecturers from the Academy of Medical Sciences to investigate the role that inflammatory procoagulant phospholipids play in arterial thrombosis (e.g. heart attacks). Alongside this, Dr Protty actively participates in data-driven research investigating the outcomes of percutaneous coronary intervention (PCI), with a focus on complex procedures, using national and multicentre datasets. 

As of March 2025, Dr Protty's clinical work is based at the University Hospital of Wales as a consultant interventional cardiologist. 

Publication

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2013

2009

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2007

Articles

Book sections

Conferences

Thesis

Research

Cardiovascular (heart) disease is the number one cause of death in the UK. Patients with heart disease who experience a heart attack are at a higher risk of suffering another heart attack, stroke or death. Heart attacks happen as a result of blockages in heart arteries. These blockages are caused by inflammation (a reaction to a damaging irritant) and lead to activation of blood cells such as white cells (responsible for wound healing) and platelets (responsible for blood clotting) which in turn lead to abnormal clotting and blockages in arteries. Treatment for these conditions include anti-thrombotic therapy (such as aspirin) and procedures to open blockages in coronary arteries (such as angioplasty and stenting).

 

Theme 1: Inflammation, Lipids and Thrombosis

Blood clotting happens through interactions of blood proteins with particular fats (phospholipids) that are present on the surface of blood cells and are linked to inflammation.  Their potential role in driving abnormal clotting events in heart attacks is unknown. If identified, it may serve as a potential new treatment. This is important since one in ten patients who experience a heart attack remain at risk of developing another heart attack, a stroke, or dying despite current treatment.

Dr Protty's research within this theme is focused on the phospholipid profile generated by blood cells in patients with heart disease, with the aim of identifying the drivers of clotting in these patients, and developing new treatment targets.

 

Theme 2: Data-driven research into cardiovascular multimorbidity and outcomes

Dr Protty actively participates in data-driven research investigating the outcomes of percutaneous coronary intervention (PCI), with a focus on complex procedures, using national and multicentre datasets. 

This theme has enabled Dr Protty to contribute to the field by developing risk-stratification tools (such as UK-BCIS CHIP Score) and study rare complications of angioplasty which would otherwise not be possible without the use of large databases of coronary interventions and outcomes. This work is part of a larger collaboration involving colleagues in Wales, the UK and Globally.

Teaching

  • Mentor/Supervisor for FUSIC Heart Echocardiography (FICE/FUSIC) (2018-)
  • Advanced Life Support (ALS) Instructor, Resus Council (UK) (2017-)
  • Associate College (RCP) Tutor, Aneurin Bevan University Healthboard (2015-17)
  • Member of the Question Writing Group (Year 1/2) and Exam Scrutiny Board (Year 3), Cardiff University (2013-14)

Biography

Dr Protty's commitment to academia began when he was 18 years old. He deferred his offer to study medicine for three years to work with Dr Mike Tomlinson (Birmingham) in a world-leading cardiovascular sciences laboratory led by British Heart Foundation (BHF) Professor Steve Watson (Birmingham). Within this time, Dr Protty investigated the intricate signalling pathways of platelets and the role they play in thrombotic and bleeding disorders.

Following this, Dr Protty started his medical training at the University of Birmingham during which he continued to pursue research opportunities. This is best exemplified by being awarded a Wellcome Trust Biomedical Vacation Scholarship to carry out research on anti-HIV RNA aptamers at the University of Oxford (Prof William James). Dr Protty graduated the MBChB (clinical medicine) course in 2013 with honours, three distinctions and 15 national and local prizes.

Subsequently, Dr Protty moved to Wales following his appointment to the highly competitive academic foundation programme in Cardiff. During this time, he continued his journey in academic cardiology and was awarded an MSc degree (Cardiff University) in therapeutics with distinction, studying the use of lipid lowering therapy in patients suffering from cardiovascular disease in Wales.

Dr Protty started his specialist cardiology training after being appointed to the Wales Clinical Academic Track (WCAT) scheme in 2015. As part of this scheme, Dr Protty developed links with the Cardiff Lipidomics group (Prof Valerie O'Donnell/Prof Peter Collins) and successfully applied to the Wellcome Trust GW4CAT scheme to pursue a PhD degree (Awarded 2021). 

Post-doctorally, Dr Protty continued on the WCAT scheme as a clnical academic cardiology registrar, focusing on the role of procoagulant phospholipids in arterial thrombosis with the aim of identifying novel anti-thrombotic therapeutic targets to improve the care of patients with cardiovascular disease. Alongside this, Dr Protty actively participates in data-driven research investigating the outcomes of percutaneous coronary intervention (PCI), with a focus on complex procedures, using national and multicentre datasets. 

As of March 2025, Dr Protty's clinical work is based at the University Hospital of Wales as a consultant interventional cardiologist. He was elected as a fellow of the Royal College of Physicians of Edinburgh (FRCP) and of the European Society of Cardiology (FESC) in recognition of his achievements to date.

Honours and awards

  • 2017 Highest Ranking Abstract in ACS category, British Cardiovascular Society Annual Conference
  • 2017 W T Edwards Research Prize, Cardiff Medical Society, Apr 2017
  • 2017 Young Investigator Award, International Liver Congress 2017, EASL
  • 2013 Chancellor’s Prize winner – this highly prestigious prize is awarded annually to a mature student whose academic progress and performance throughout the course have been outstanding and who has also made an outstanding contribution to the general life of the University as a whole, University of Birmingham.
  • 2013 BPS Undergraduate prize in Clinical Pharmacology, British Pharmacological Society
  • 2013 Arthur Foxwell Memorial Prize in Medicine winner – awarded to the highest scoring student in Clinical Medicine, University of Birmingham
  • 2013 The Medical Society Cup, University of Birmingham
  • 2012 British Medical and Dental Students Trust (BMDST) Elective Travel Scholarship
  • 2012 Arthur Thomson Trust Elective Travel Scholarship, University of Birmingham
  • 2011 First Prize for the Leith Neumann prize in Pathological studies, University of Birmingham
  • 2011 Prize for best oral presentation in the immunology session at the LIMSC International Conference, Leiden University, NL
  • 2010 The Wellcome Trust Biomedical Vacation Scholarship, to fund a research project at the University of Oxford.

Professional memberships

  • Fellow of the European Society of Cardiology (FESC)
  • Fellow of the Royal College of Physicians of Edinburgh (FRCP)
  • European Association of PCI (EAPCI) certified interventional cardiologist
  • British Cardiovascular Society (BCS)
  • British Society of Echocardiography (BSE) - Full accreditation in transthoracic echocardiography
  • British Cardiovascular Intervention Society (BCIS) - Fellow editor
  • British Medical Association (BMA)
  • General Medical Council (GMC)
  • Member of the Royal College of Physicians (MRCP London)
  • Member of the Academy of Medical Educators (MAcadMEd)

Academic positions

  • PhD Viva External Examiner (2025-)

Committees and reviewing

  • Member of the BMA Medical Academic Staff Committee (MASC), 2019-2021
  • Wales Representative to the British Junior Cardiologists Association (BJCA), 2020-
  • Grant Reviewer - MRC, Wellcome 2018-
  • Journal Reviewer - Platelets, EHJ QCCO, BMJ Open, JACC, IJCP, Function, ICR3
  • Education committee for Physician trainees, Aneurin Bevan University Health Board 2015-2017

Contact Details

Email [email protected]

Campuses Sir Geraint Evans Cardiovascular Research Building, University Hospital of Wales, Heath Park, Cardiff, CF14 4XN

Research themes

Specialisms

  • Cardiology
  • Cardiovascular diseases
  • Lipids
  • Thrombosis
  • Platelets

External profiles