![Fiona Ruge](https://profiles-cardiff.imgix.net/attachments/2591?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Overview
After graduating with a BSc in Applied Biology from the University of East London, I joined the Department of Anatomy at Guy's Hospital, London. It was there that my passion and interest in histology started. Since joining Cardiff University in 1996, I have worked in Departments of Wound Healing, Dermatology and CCMRC. In this role I am involved in several research projects supporting academics, postdoctoral fellows and postgraduate students. My area of expertise is processing and sectioning of frozen and paraffin embedded tissue, and subsequent histology, immunofluorescence and immunoperoxidase staining. I am also Deputy DSO for CCMRC.
Publication
2024
- Fang, Z. et al. 2024. Implication of capillary morphogenesis gene 2 (CMG2) in the disease progression and peritoneal metastasis of pancreatic cancer. Cancers 16(16), article number: 2893. (10.3390/cancers16162893)
- Li, A. X. et al. 2024. Metastatic Lymph Node 64 (MLN64) expression in gastric cancer, the clinical and molecular implications in drug resistance. Cancer Genomics & Proteomics 21(1), pp. 30-40. (10.21873/cgp.20427)
2023
- Cai, S. et al. 2023. Kinase D-interacting substrate of 220kDa is overexpressed in gastric cancer and associated with local invasion. Cancer Genomics & Proteomics 20(6suppl), pp. 735-743. (10.21873/cgp.20420)
- Zhuang, X. et al. 2023. Expression of Claudin-9 (CLDN9) in breast cancer, the clinical significance in connection with its subcoat anchorage proteins ZO-1 and ZO-3 and impact on drug resistance. Biomedicines 11(12), article number: 3136. (10.3390/biomedicines11123136)
- Zhuang, X. et al. 2023. Claudin-10 in the blood brain barrier function of cerebral endothelial cells and transendothelial invasion of breast cancer cells. Anticancer Research 43(9), pp. 3923-3934. (10.21873/anticanres.16580)
- Lohana, P. et al. 2023. Role of enzymic antioxidants in mediating oxidative stress and contrasting wound healing capabilities in oral mucosal/skin fibroblasts and tissues. Antioxidants 12(7), article number: 1374. (10.3390/antiox12071374)
- Fang, Z., Zeng, J. J., Yang, Y., Ruge, F., Lane, J., Hargest, R. and Jiang, W. 2023. Expression of ALCAM in clinical colon cancer and relationship with patients' treatment responses. In Vivo 37(3), pp. 1117-1128. (10.21873/invivo.13187)
- Ming Yang, Y. et al. 2023. ALCAM, Activated leukocyte cell adhesion molecule, in clinical gastric cancer and patient's response to chemotherapies. Anticancer Research 43(4), pp. 1463-1475. (10.21873/anticanres.16295)
- Frugtniet, B. A., Ruge, F., Sanders, A. J., Owen, S., Harding, K. G., Jiang, W. G. and Martin, T. A. 2023. nWASP inhibition increases wound healing via TrKb/PLCγ signalling. Biomolecules 13(2), article number: 379. (10.3390/biom13020379)
- Yang, Y. M. et al. 2023. Activated leukocyte cell adhesion molecule (alcam), a potential 'seed' and 'soil' receptor in the peritoneal metastasis of gastrointestinal cancers. International Journal of Molecular Sciences 24(1), article number: 876. (10.3390/ijms24010876)
- Li, A. X. et al. 2023. Striatins and the STRIPAK complex partners in the clinical outcome of patients with breast cancer and responses to drug treatment. Chinese Journal of Cancer Research 35, pp. 365-385. (10.21147/j.issn.1000-9604.2023.04.04)
2022
- Zeng, J., Sanders, A. J., Lin, Y., Hargest, R., Ruge, F. and Jiang, W. G. 2022. EPLIN, a putative tumour suppressor in colorectal cancer, implications in drug resistance. International Journal of Molecular Sciences 23(23), article number: 15232. (10.3390/ijms232315232)
- Fang, Z. et al. 2022. Sex hormone-regulatedcmg2is involved in breast and prostate cancer progression. Cancer Genomics & Proteomics 19(6), pp. 703-710. (10.21873/cgp.20353)
- Fang, Z. et al. 2022. Sex hormone-regulated CMG2 is involved in breast and prostate cancer progression. Cancer Genomics & Proteomics 19, pp. 703-710.
- Sui, L. et al. 2022. Death associated protein-3 (DAP3) and DAP3 binding cell death enhancer-1 (DELE1) in human colorectal cancer, and their impacts on clinical outcome and chemoresistance. International Journal of Oncology 62(1), article number: 7. (10.3892/ijo.2022.5455)
- Telford, E. A., Sanders, A. J., Owen, S., Ruge, F., Harrison, G. M., Jiang, W. G. and Martin, T. A. 2022. Hepatitis A virus cellular receptor 1 (HAVcr-1) initiates prostate cancer progression in human cells via hepatocyte growth factor (HGF)-induced changes in junctional integrity. Biomolecules 12(2), article number: 338. (10.3390/biom12020338)
2021
- Bosanquet, D. C. et al. 2021. Sensitivity of the wound edge gene signature "WD14" in responding to clinical change: a longitudinal cohort study. International Journal of Lower Extremity Wounds (10.1177/15347346211056786)
- Xin, L. et al. 2021. SIKs suppress tumor function and regulate drug resistance in breast cancer. American Journal of Cancer Research 11(7), pp. 3537-3557.
- Yang, Y. et al. 2021. Activated leukocyte cell adhesion molecule (ALCAM)/CD166 in pancreatic cancer, a pivotal link to clinical outcome and vascular embolism. American Journal of Cancer Research 11(12), pp. 5917-5932.
- Cui, Y., Hunt, A., Li, Z., Birkin, E., Lane, J., Ruge, F. and Jiang, W. G. 2021. Lead DEAD/H box helicase biomarkers with the therapeutic potential identified by integrated bioinformatic approaches in lung cancer. Computational and Structural Biotechnology Journal 19, pp. 261-278. (10.1016/j.csbj.2020.12.007)
2020
- Cong, Y. et al. 2020. Calcium-binding protein S100P promotes tumor progression but enhances chemosensitivity in breast cancer. Frontiers in Oncology 10, article number: 566302. (10.3389/fonc.2020.566302)
- Sun, Z. et al. 2020. Noggin is associated with a poor prognosis of gastric cancer by promoting the proliferation of gastric cancer cells via the upregulation of EGFR. International Journal of Oncology 57(3), pp. 813-824. (10.3892/ijo.2020.5081)
- Liu, J. et al. 2020. Increased expression of Psoriasin is correlated with poor prognosis of bladder transitional cell carcinoma by promoting invasion and proliferation. Oncology Reports 43(2), pp. 562-570. (10.3892/or.2019.7445)
2019
- Sanders, A. et al. 2019. Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination. Oncotarget 10(59), pp. 6362-6377. (10.18632/oncotarget.27279)
- Bosanquet, D. C., Sanders, A. J., Ruge, F., Lane, J., Morris, C. A., Jiang, W. G. and Harding, K. G. 2019. Development and validation of a gene expression test to identify hard-to-heal chronic venous leg ulcers. British Journal of Surgery 106(8), pp. 1035-1042. (10.1002/bjs.11161)
2018
- Collins, R., Morgan, L., Owen, S., Ruge, F., Jiang, W. and Sanders, A. 2018. Mechanistic insights of epithelial protein lost in neoplasm in prostate cancer metastasis. International Journal of Cancer 143(10), pp. 2537-2550. (10.1002/ijc.31786)
- Harries, R. L. et al. 2018. Impact of pigment epithelium-derived factor on colorectal cancer in vitro and in vivo. Oncotarget 9(27), pp. 19192-19202. (10.18632/oncotarget.24953)
2017
- Lopes-Bastos, B. et al. 2017. Association of breast carcinoma growth with a non-canonical axis of IFNγ/IDO1/TSP1. Oncotarget (10.18632/oncotarget.18781)
- Yang, W., Cai, J., Zabkiewicz, C., Zhang, H., Ruge, F. and Jiang, W. 2017. The effects of anesthetics on recurrence and metastasis of cancer, and clinical implications. World Journal of Oncology 8(3), pp. 63-70. (10.14740/wjon1031e)
- Owen, S. et al. 2017. The clinical and biological implications of the focal adhesion kinase pathway in ShenLingLan mediated suppression of cellular migration of ovarian cancer cells. Journal of Cancer Research & Therapy 5, pp. 24-31. (10.14312/2052-4994.2017-5)
- Cai, S. et al. 2017. Expression of phospholipase C isozymes in human breast cancer and their clinical significance. Oncology Reports 37(3), pp. 1707-1715. (10.3892/or.2017.5394)
- Owen, S. et al. 2017. ShenLingLan influences the attachment and migration of ovarian cancer cells potentially through the GSK3 pathway. Medicines 7, pp. 1-11.
- Li, J. et al. 2017. Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells. Oncotarget (10.18632/oncotarget.15439)
- Feng, Y., Sanders, A. J., Morgan, L. D., Owen, S., Ruge, F., Harding, K. G. and Jiang, W. G. 2017. In vitro significance of SOCS-3 and SOCS-4 and potential mechanistic links to wound healing. Scientific Reports 7(1), article number: 6715. (10.1038/s41598-017-06886-6)
2016
- Feng, Y., Sanders, A., Ruge, F., Morris, C., Harding, K. and Jiang, W. 2016. Expression of the SOCS family in human chronic wound tissues: Potential implications for SOCS in chronic wound healing. International Journal of Molecular Medicine 38(5), pp. 1349-1358. (10.3892/ijmm.2016.2733)
- Owen, S. et al. 2016. Heat shock protein 27 is a potential indicator for response to YangZheng XiaoJi and chemotherapy agents in cancer cells. International Journal of Oncology 49, pp. 1839-1847. (10.3892/ijo.2016.3685)
- Jones, A. M., Griffiths, J. L., Sanders, A. J., Owen, S., Ruge, F., Harding, K. and Jiang, W. G. 2016. The clinical significance and impact of interleukin 15 on keratinocyte cell growth and migration. International Journal of Molecular Medicine 38, pp. 679-686. (10.3892/ijmm.2016.2687)
- Bartlett, A., Sanders, A. J., Ruge, F., Harding, K. G. and Jiang, W. G. 2016. Potential implications of interleukin-7 in chronic wound healing. Experimental and Therapeutic Medicine 12(1), pp. 33-40. (10.3892/etm.2016.3263)
- Liu, R., Martin, T. A., Jordan, N., Ruge, F., Ye, L. and Jiang, W. G. 2016. Epithelial protein lost in neoplasm-α (EPLIN-α) is a potential prognostic marker for the progression of epithelial ovarian cancer. International Journal of Oncology 48(6), pp. 2488-2496. (10.3892/ijo.2016.3462)
- Zhao, H. et al. 2016. The clinical implications of RSK1-3 in human breast cancer. Anticancer Research 36(3), pp. 1267-1274.
- Jiang, W. G. et al. 2016. Effects of YangZheng XiaoJi on the migration and growth of lung cancer cells, by targeting the Hepatocyte Growth Factor Receptor-Epidermal Growth Factor Receptor (HGFR-EGFR) transactivation [Abstract]. European Journal of Cancer 51(S3), pp. S642-S642., article number: 3117. (10.1016/S0959-8049(16)31758-0)
- Wang, S., Ye, L., Sanders, A. J., Ruge, F., Harding, K. G. and Jiang, W. G. 2016. Tumour endothelial marker-8 in wound healing and its impact on the proliferation and migration of keratinocytes. International Journal of Molecular Medicine 37(2), pp. 293-298. (10.3892/ijmm.2015.2434)
2015
- Zhang, L. et al. 2015. Reversal of pathological features of Graves' orbitopathy by activation of forkhead transcription factors, FOXOs. Journal of Clinical Endocrinology & Metabolism 101(1), pp. 114-122. (10.1210/jc.2015-2932)
- Wang, L., Cui, Y., Ruge, F. and Jiang, W. G. 2015. Interleukin 21 and its receptor play a role in proliferation, migration and invasion of breast cancer cells. Cancer Genomics and Proteomics 12(5), pp. 211-221.
- Tan, Y., Sanders, A. J., Xie, Y., Martin, T. A., Owen, S., Ruge, F. and Jiang, W. G. 2015. Interleukin-24 (IL-24) expression and biological impact on HECV endothelial cells.. Cancer Genomics and Proteomics 12(5), pp. 243-250.
- Liu, R., Martin, T. A., Jordan, N. J., Ruge, F., Ye, L. and Jiang, W. G. 2015. Metastasis suppressor 1 expression in human ovarian cancer: the impact on cellular migration and metastasis. International Journal of Oncology 47(4), pp. 1429-1439. (10.3892/ijo.2015.3121)
- Jiang, W. G. et al. 2015. 3117 Effects of YangZheng XiaoJi on the migration and growth of lung cancer cells, by targeting the Hepatocyte Growth Factor Receptor-Epidermal Growth Factor Receptor (HGFR-EGFR) transactivation. European Journal of Cancer 51(Supp 1), pp. S642. (10.1016/S0959-8049(16)31758-0)
- Jiang, W. G. et al. 2015. YangZheng XiaoJi exerts anti-tumour growth effects by antagonising the effects of HGF and its receptor, cMET, in human lung cancer cells. Journal of Translational Medicine 13, article number: 280. (10.1186/s12967-015-0639-1)
- Liu, R., Jordan, N., Martin, T. A., Ruge, F., Ye, L. and Jiang, W. G. 2015. Metastasis suppressor 1 (MTSS1) expression in human ovarian cancer; the impact on cellular migration and metastasis [Abstract]. Anticancer Research 35(7), pp. 4342-4342.
- Jiang, W. et al. 2015. Expression of Sonic Hedgehog (SHH) in human lung cancer and the impact of YangZheng XiaoJi on SHH-mediated biological function of lung cancer cells and tumor growth.. Anticancer Research 35(3), pp. 1321-1331.
- Glasbey, J., Sanders, A. J., Bosanquet, D. C., Ruge, F., Harding, K. G. and Jiang, W. 2015. Expression of hepatocyte growth factor-like protein in human wound tissue and its biological functionality in human keratinocytes. Biomedicines 3(1), pp. 110-123. (10.3390/biomedicines3010110)
- Men, W., Martin, T. A., Ruge, F., Zhang, N., Du, P., Yang, Y. and Jiang, W. G. 2015. Expression of claudins in human clear cell renal cell carcinoma. Cancer Genomics and Proteomics 12(1), pp. 1-8.
2014
- Jones, A. M., Sanders, A. J., Ruge, F., Harding, K. G. and Jiang, W. G. 2014. The expression of interleukin 17c (IL-17c) in chronic wounds and its effect on an in vitro model of keratinocyte cell migration [Abstract]. Wound Repair and Regeneration 22(5), pp. A85-A85. (10.1111/wrr.12218)
- Jiang, W. G., Sanders, A. J., Cox, E. D., Bosanquet, D. C., Ruge, F., Lane, J. and Harding, K. G. 2014. A gene expression signature that predicted the clinical outcome of chronic wounds [Abstract]. Wound Repair and Regeneration 22(5), pp. A84-A84. (10.1111/wrr.12218)
- Martin, T. A., Ruge, F., Harding, K. G. and Jiang, W. G. 2014. Brain-derived neurotrophic factor (bdnf) is a novel therapeutic agent in human wound healing [Abstract]. Wound Repair and Regeneration 22(5), pp. A91. (10.1111/wrr.12218)
- Jones, A. M., Sanders, A. J., Griffiths, J. L., Ruge, F., Harding, K. G. and Jiang, W. G. 2014. The effect of interleukin 15 on an in vitro model of human keratinocyte cell migration in wound healing. British Journal of Surgery 101(S4), pp. 25., article number: O86. (10.1002/bjs.9508)
- Jia, S. et al. 2014. Down-regulation of WAVE2, WASP family verprolin-homologous protein 2, in gastric cancer indicates lymph node metastasis and cell migration.. Anticancer Research 34(5), pp. 2185-2194.
- Jones, A. M., Sanders, A. J., Ruge, F., Harding, K. G. and Jiang, W. G. 2014. The effect of interleukin-17B on an in vitro model of human keratinocyte cell migration during wound healing. British Journal of Surgery 101(s4), pp. 28., article number: O97. (10.1002/bjs.9508)
- Jia, Y. et al. 2014. Death associated protein 1 is correlated with the clinical outcome of patients with colorectal cancer and has a role in the regulation of cell death. Oncology Reports 31(1), pp. 175-182. (10.3892/or.2013.2866)
- Feng, Y., Sanders, A. J., Ruge, F., Harding, K. G. and Jiang, W. G. 2014. Expression of the suppressor of cytokine signalling (SOCS) family members in chronic wound tissue. Wound Repair and Regeneration 22(5), pp. A79-A79. (10.1111/wrr.12218)
- Ji, K., Ye, L., Ruge, F., Hargest, R., Mason, M. D. and Jiang, W. G. 2014. Implication of metastasis suppressor gene, Kiss-1 and its receptor Kiss-1R in colorectal cancer. BMC Cancer 14, article number: 723. (10.1186/1471-2407-14-723)
2013
- Jiang, W. G., Ye, L., Sanders, A. J., Ruge, F., Kynaston, H., Ablin, R. J. and Mason, M. D. 2013. Prostate transglutaminase (TGase-4, TGaseP) enhances the adhesion of prostate cancer cells to extracellular matrix, the potential role of TGase-core domain. Journal of Translational Medicine 11, article number: 269. (10.1186/1479-5876-11-269)
- Sobkowicz, A., Sanders, A. J., Ruge, F. and Jiang, W. G. 2013. Expression profile of amphyphysin I in normal and breast cancer specimens. European Journal of Cancer 49, pp. S198-S198.
- Jiang, W. G. et al. 2013. Antitumour effects of Yangzheng Xiaoji in human osteosarcoma: The pivotal role of focal adhesion kinase signalling. Oncology Reports 30(3), pp. 1405-1413. (10.3892/or.2013.2586)
2012
- Bosanquet, D. C., Harding, K. G., Ruge, F., Sanders, A. J. and Jiang, W. G. 2012. Expression of IL-24 and IL-24 receptors in human wound tissues and the biological implications of IL-24 on keratinocytes. Wound Repair and Regeneration 20(6), pp. 896-903. (10.1111/j.1524-475X.2012.00840.x)
- Du, P., Ye, L., Ruge, F., Yang, Y. and Jiang, W. G. 2012. Loss of expression of growth differentiation factor-9 (GDF9) in human kidney cancer and regulation of growth and migration of kidney cancer cells by GDF9. Anticancer Research 32(10), pp. 4375-4383.
- Ji, K. et al. 2012. Expression of signal-induced proliferation-associated gene 1 (SIPA1), a rapGTPase-activating protein, is increased in colorectal cancer and has diverse effects on functions of colorectal cancer cells. Cancer Genomics and Proteomics 9(5), pp. 321-327.
- Jiang, W. G., Sanders, A. J., Ruge, F. and Harding, K. G. 2012. Influence of interleukin-8 (IL-8) and IL-8 receptors on the migration of human keratinocytes, the role of PLC-γ and potential clinical implications. Experimental and Therapeutic Medicine 3(2), pp. 231-236. (10.3892/etm.2011.402)
- Du, P., Ye, L., Li, H., Ruge, F., Yang, Y. and Jiang, W. G. 2012. Growth differentiation factor-9 expression is inversely correlated with an aggressive behaviour in human bladder cancer cells. International Journal of Molecular Medicine 29(3), pp. 428-434. (10.3892/ijmm.2011.858)
2011
- Ruge, F. et al. 2011. Delineating immune-mediated mechanisms underlying hair follicle destruction in the mouse mutant defolliculated. Journal of Investigative Dermatology 131(3), pp. 572-579. (10.1038/jid.2010.379)
- Du, P., Ye, L., Ruge, F., Yang, Y. and Jiang, W. G. 2011. Metastasis suppressor-1, MTSS1, acts as a putative tumour suppressor in human bladder cancer. Anticancer Research 31(10), pp. 3205-3212.
- Minhas, U., Martin, T. A., Ruge, F., Harding, K. G. and Jiang, W. G. 2011. Pattern of expression of CCN family members Cyr61, CTGF and NOV in human acute and chronic wounds. Experimental and Therapeutic Medicine 2(4), pp. 641-645. (10.3892/etm.2011.256)
2007
- Conway, K. P., Ruge, F., Price, P. E., Harding, K. G. and Jiang, W. G. 2007. Hepatocyte growth factor regulation: an integral part of why wounds become chronic. Wound Repair and Regeneration 15(5), pp. 683-692. (10.1111/j.1524-475X.2007.00296.x)
Erthyglau
- Fang, Z. et al. 2024. Implication of capillary morphogenesis gene 2 (CMG2) in the disease progression and peritoneal metastasis of pancreatic cancer. Cancers 16(16), article number: 2893. (10.3390/cancers16162893)
- Li, A. X. et al. 2024. Metastatic Lymph Node 64 (MLN64) expression in gastric cancer, the clinical and molecular implications in drug resistance. Cancer Genomics & Proteomics 21(1), pp. 30-40. (10.21873/cgp.20427)
- Cai, S. et al. 2023. Kinase D-interacting substrate of 220kDa is overexpressed in gastric cancer and associated with local invasion. Cancer Genomics & Proteomics 20(6suppl), pp. 735-743. (10.21873/cgp.20420)
- Zhuang, X. et al. 2023. Expression of Claudin-9 (CLDN9) in breast cancer, the clinical significance in connection with its subcoat anchorage proteins ZO-1 and ZO-3 and impact on drug resistance. Biomedicines 11(12), article number: 3136. (10.3390/biomedicines11123136)
- Zhuang, X. et al. 2023. Claudin-10 in the blood brain barrier function of cerebral endothelial cells and transendothelial invasion of breast cancer cells. Anticancer Research 43(9), pp. 3923-3934. (10.21873/anticanres.16580)
- Lohana, P. et al. 2023. Role of enzymic antioxidants in mediating oxidative stress and contrasting wound healing capabilities in oral mucosal/skin fibroblasts and tissues. Antioxidants 12(7), article number: 1374. (10.3390/antiox12071374)
- Fang, Z., Zeng, J. J., Yang, Y., Ruge, F., Lane, J., Hargest, R. and Jiang, W. 2023. Expression of ALCAM in clinical colon cancer and relationship with patients' treatment responses. In Vivo 37(3), pp. 1117-1128. (10.21873/invivo.13187)
- Ming Yang, Y. et al. 2023. ALCAM, Activated leukocyte cell adhesion molecule, in clinical gastric cancer and patient's response to chemotherapies. Anticancer Research 43(4), pp. 1463-1475. (10.21873/anticanres.16295)
- Frugtniet, B. A., Ruge, F., Sanders, A. J., Owen, S., Harding, K. G., Jiang, W. G. and Martin, T. A. 2023. nWASP inhibition increases wound healing via TrKb/PLCγ signalling. Biomolecules 13(2), article number: 379. (10.3390/biom13020379)
- Yang, Y. M. et al. 2023. Activated leukocyte cell adhesion molecule (alcam), a potential 'seed' and 'soil' receptor in the peritoneal metastasis of gastrointestinal cancers. International Journal of Molecular Sciences 24(1), article number: 876. (10.3390/ijms24010876)
- Li, A. X. et al. 2023. Striatins and the STRIPAK complex partners in the clinical outcome of patients with breast cancer and responses to drug treatment. Chinese Journal of Cancer Research 35, pp. 365-385. (10.21147/j.issn.1000-9604.2023.04.04)
- Zeng, J., Sanders, A. J., Lin, Y., Hargest, R., Ruge, F. and Jiang, W. G. 2022. EPLIN, a putative tumour suppressor in colorectal cancer, implications in drug resistance. International Journal of Molecular Sciences 23(23), article number: 15232. (10.3390/ijms232315232)
- Fang, Z. et al. 2022. Sex hormone-regulatedcmg2is involved in breast and prostate cancer progression. Cancer Genomics & Proteomics 19(6), pp. 703-710. (10.21873/cgp.20353)
- Fang, Z. et al. 2022. Sex hormone-regulated CMG2 is involved in breast and prostate cancer progression. Cancer Genomics & Proteomics 19, pp. 703-710.
- Sui, L. et al. 2022. Death associated protein-3 (DAP3) and DAP3 binding cell death enhancer-1 (DELE1) in human colorectal cancer, and their impacts on clinical outcome and chemoresistance. International Journal of Oncology 62(1), article number: 7. (10.3892/ijo.2022.5455)
- Telford, E. A., Sanders, A. J., Owen, S., Ruge, F., Harrison, G. M., Jiang, W. G. and Martin, T. A. 2022. Hepatitis A virus cellular receptor 1 (HAVcr-1) initiates prostate cancer progression in human cells via hepatocyte growth factor (HGF)-induced changes in junctional integrity. Biomolecules 12(2), article number: 338. (10.3390/biom12020338)
- Bosanquet, D. C. et al. 2021. Sensitivity of the wound edge gene signature "WD14" in responding to clinical change: a longitudinal cohort study. International Journal of Lower Extremity Wounds (10.1177/15347346211056786)
- Xin, L. et al. 2021. SIKs suppress tumor function and regulate drug resistance in breast cancer. American Journal of Cancer Research 11(7), pp. 3537-3557.
- Yang, Y. et al. 2021. Activated leukocyte cell adhesion molecule (ALCAM)/CD166 in pancreatic cancer, a pivotal link to clinical outcome and vascular embolism. American Journal of Cancer Research 11(12), pp. 5917-5932.
- Cui, Y., Hunt, A., Li, Z., Birkin, E., Lane, J., Ruge, F. and Jiang, W. G. 2021. Lead DEAD/H box helicase biomarkers with the therapeutic potential identified by integrated bioinformatic approaches in lung cancer. Computational and Structural Biotechnology Journal 19, pp. 261-278. (10.1016/j.csbj.2020.12.007)
- Cong, Y. et al. 2020. Calcium-binding protein S100P promotes tumor progression but enhances chemosensitivity in breast cancer. Frontiers in Oncology 10, article number: 566302. (10.3389/fonc.2020.566302)
- Sun, Z. et al. 2020. Noggin is associated with a poor prognosis of gastric cancer by promoting the proliferation of gastric cancer cells via the upregulation of EGFR. International Journal of Oncology 57(3), pp. 813-824. (10.3892/ijo.2020.5081)
- Liu, J. et al. 2020. Increased expression of Psoriasin is correlated with poor prognosis of bladder transitional cell carcinoma by promoting invasion and proliferation. Oncology Reports 43(2), pp. 562-570. (10.3892/or.2019.7445)
- Sanders, A. et al. 2019. Importance of activated leukocyte cell adhesion molecule (ALCAM) in prostate cancer progression and metastatic dissemination. Oncotarget 10(59), pp. 6362-6377. (10.18632/oncotarget.27279)
- Bosanquet, D. C., Sanders, A. J., Ruge, F., Lane, J., Morris, C. A., Jiang, W. G. and Harding, K. G. 2019. Development and validation of a gene expression test to identify hard-to-heal chronic venous leg ulcers. British Journal of Surgery 106(8), pp. 1035-1042. (10.1002/bjs.11161)
- Collins, R., Morgan, L., Owen, S., Ruge, F., Jiang, W. and Sanders, A. 2018. Mechanistic insights of epithelial protein lost in neoplasm in prostate cancer metastasis. International Journal of Cancer 143(10), pp. 2537-2550. (10.1002/ijc.31786)
- Harries, R. L. et al. 2018. Impact of pigment epithelium-derived factor on colorectal cancer in vitro and in vivo. Oncotarget 9(27), pp. 19192-19202. (10.18632/oncotarget.24953)
- Lopes-Bastos, B. et al. 2017. Association of breast carcinoma growth with a non-canonical axis of IFNγ/IDO1/TSP1. Oncotarget (10.18632/oncotarget.18781)
- Yang, W., Cai, J., Zabkiewicz, C., Zhang, H., Ruge, F. and Jiang, W. 2017. The effects of anesthetics on recurrence and metastasis of cancer, and clinical implications. World Journal of Oncology 8(3), pp. 63-70. (10.14740/wjon1031e)
- Owen, S. et al. 2017. The clinical and biological implications of the focal adhesion kinase pathway in ShenLingLan mediated suppression of cellular migration of ovarian cancer cells. Journal of Cancer Research & Therapy 5, pp. 24-31. (10.14312/2052-4994.2017-5)
- Cai, S. et al. 2017. Expression of phospholipase C isozymes in human breast cancer and their clinical significance. Oncology Reports 37(3), pp. 1707-1715. (10.3892/or.2017.5394)
- Owen, S. et al. 2017. ShenLingLan influences the attachment and migration of ovarian cancer cells potentially through the GSK3 pathway. Medicines 7, pp. 1-11.
- Li, J. et al. 2017. Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells. Oncotarget (10.18632/oncotarget.15439)
- Feng, Y., Sanders, A. J., Morgan, L. D., Owen, S., Ruge, F., Harding, K. G. and Jiang, W. G. 2017. In vitro significance of SOCS-3 and SOCS-4 and potential mechanistic links to wound healing. Scientific Reports 7(1), article number: 6715. (10.1038/s41598-017-06886-6)
- Feng, Y., Sanders, A., Ruge, F., Morris, C., Harding, K. and Jiang, W. 2016. Expression of the SOCS family in human chronic wound tissues: Potential implications for SOCS in chronic wound healing. International Journal of Molecular Medicine 38(5), pp. 1349-1358. (10.3892/ijmm.2016.2733)
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