![Lucy Satherley](https://profiles-cardiff.imgix.net/attachments/437?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Publication
2017
- Cai, S. et al. 2017. Expression of phospholipase C isozymes in human breast cancer and their clinical significance. Oncology Reports 37 (3), pp.1707-1715. (10.3892/or.2017.5394)
- Chen, G. et al., 2017. The downstream of tyrosine kinase 7 is reduced in lung cancer and is associated with poor survival of patients with lung cancer. Oncology Reports 37 (5), pp.2695-2701. (10.3892/or.2017.5538)
- Li, J. et al., 2017. Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells. Oncotarget (10.18632/oncotarget.15439)
- Liu, Y. et al. 2017. Psoriasin promotes invasion, aggregation and survival of pancreatic cancer cells; association with disease progression. International Journal of Oncology 50 (5), pp.1491-1500. (10.3892/ijo.2017.3953)
- Satherley, L. 2017. The role of DOK7 and its variants in colorectal cancer. PhD Thesis , Cardiff University.
2016
- Jiang, W. G. et al. 2016. Effects of YangZheng XiaoJi on the migration and growth of lung cancer cells, by targeting the Hepatocyte Growth Factor Receptor-Epidermal Growth Factor Receptor (HGFR-EGFR) transactivation [Abstract]. European Journal of Cancer 51 (S3), pp.S642-S642. 3117. (10.1016/S0959-8049(16)31758-0)
- Malik, M. F. A. et al., 2016. Expression of semaphorin 3C in breast cancer and its impact on adhesion and invasion of breast cancer cells. Anticancer Research 36 (3), pp.1281-1286.
- Satherley, L. et al. 2016. Prostate Apoptosis Response-4 (PAR4) suppresses growth and invasion of breast cancer cells and is positively associated with patient survival. Anticancer Research 36 (3), pp.1227-1236.
- Shao, S. et al., 2016. Reduced RanBPM expression is associated with distant metastasis in gastric cancer and chemoresistance. Anticancer Research 36 (3), pp.1295-1304.
2015
- Jiang, W. et al. 2015. Expression of Sonic Hedgehog (SHH) in human lung cancer and the impact of YangZheng XiaoJi on SHH-mediated biological function of lung cancer cells and tumor growth.. Anticancer Research 35 (3), pp.1321-1331.
- Jiang, W. G. et al. 2015. YangZheng XiaoJi exerts anti-tumour growth effects by antagonising the effects of HGF and its receptor, cMET, in human lung cancer cells. Journal of Translational Medicine 13 280. (10.1186/s12967-015-0639-1)
- Jiang, W. G. et al. 2015. 3117 Effects of YangZheng XiaoJi on the migration and growth of lung cancer cells, by targeting the Hepatocyte Growth Factor Receptor-Epidermal Growth Factor Receptor (HGFR-EGFR) transactivation. European Journal of Cancer 51 (Supp 1), pp.S642. (10.1016/S0959-8049(16)31758-0)
- Li, J. et al. 2015. MTA1 is up-regulated in colorectal cancer and is inversely correlated with lymphatic metastasis. Cancer Genomics and Proteomics 12 (6), pp.339-346.
- Satherley, L. et al. 2015. Expression of lymphangiogenic factors Vegf-C and Vegf-D and impact of Vegf-D knockout on tubule formation in human colorectal cancer [Abstract]. British Journal of Surgery 102 (s1), pp.8-8. 0700. (10.1002/bjs.9735)
- Satherley, L. et al. 2015. Downstream of tyrosine kinase 7 (DOK7) variant expression and function in human colorectal cancer [Abstract]. European Journal of Cancer 51 (S3), pp.S27. (10.1016/S0959-8049(15)30004-6)
2014
- Satherley, L. et al. 2014. DOK7 expression in colorectal cancer cells and association with clinical and prognostic outcome [Abstract]. British Journal of Surgery 101 (S4), pp.12. O34. (10.1002/bjs.9508)
Articles
- Cai, S. et al. 2017. Expression of phospholipase C isozymes in human breast cancer and their clinical significance. Oncology Reports 37 (3), pp.1707-1715. (10.3892/or.2017.5394)
- Chen, G. et al., 2017. The downstream of tyrosine kinase 7 is reduced in lung cancer and is associated with poor survival of patients with lung cancer. Oncology Reports 37 (5), pp.2695-2701. (10.3892/or.2017.5538)
- Jiang, W. et al. 2015. Expression of Sonic Hedgehog (SHH) in human lung cancer and the impact of YangZheng XiaoJi on SHH-mediated biological function of lung cancer cells and tumor growth.. Anticancer Research 35 (3), pp.1321-1331.
- Jiang, W. G. et al. 2015. YangZheng XiaoJi exerts anti-tumour growth effects by antagonising the effects of HGF and its receptor, cMET, in human lung cancer cells. Journal of Translational Medicine 13 280. (10.1186/s12967-015-0639-1)
- Jiang, W. G. et al. 2015. 3117 Effects of YangZheng XiaoJi on the migration and growth of lung cancer cells, by targeting the Hepatocyte Growth Factor Receptor-Epidermal Growth Factor Receptor (HGFR-EGFR) transactivation. European Journal of Cancer 51 (Supp 1), pp.S642. (10.1016/S0959-8049(16)31758-0)
- Jiang, W. G. et al. 2016. Effects of YangZheng XiaoJi on the migration and growth of lung cancer cells, by targeting the Hepatocyte Growth Factor Receptor-Epidermal Growth Factor Receptor (HGFR-EGFR) transactivation [Abstract]. European Journal of Cancer 51 (S3), pp.S642-S642. 3117. (10.1016/S0959-8049(16)31758-0)
- Li, J. et al. 2015. MTA1 is up-regulated in colorectal cancer and is inversely correlated with lymphatic metastasis. Cancer Genomics and Proteomics 12 (6), pp.339-346.
- Li, J. et al., 2017. Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells. Oncotarget (10.18632/oncotarget.15439)
- Liu, Y. et al. 2017. Psoriasin promotes invasion, aggregation and survival of pancreatic cancer cells; association with disease progression. International Journal of Oncology 50 (5), pp.1491-1500. (10.3892/ijo.2017.3953)
- Malik, M. F. A. et al., 2016. Expression of semaphorin 3C in breast cancer and its impact on adhesion and invasion of breast cancer cells. Anticancer Research 36 (3), pp.1281-1286.
- Satherley, L. et al. 2015. Expression of lymphangiogenic factors Vegf-C and Vegf-D and impact of Vegf-D knockout on tubule formation in human colorectal cancer [Abstract]. British Journal of Surgery 102 (s1), pp.8-8. 0700. (10.1002/bjs.9735)
- Satherley, L. et al. 2016. Prostate Apoptosis Response-4 (PAR4) suppresses growth and invasion of breast cancer cells and is positively associated with patient survival. Anticancer Research 36 (3), pp.1227-1236.
- Satherley, L. et al. 2014. DOK7 expression in colorectal cancer cells and association with clinical and prognostic outcome [Abstract]. British Journal of Surgery 101 (S4), pp.12. O34. (10.1002/bjs.9508)
- Satherley, L. et al. 2015. Downstream of tyrosine kinase 7 (DOK7) variant expression and function in human colorectal cancer [Abstract]. European Journal of Cancer 51 (S3), pp.S27. (10.1016/S0959-8049(15)30004-6)
- Shao, S. et al., 2016. Reduced RanBPM expression is associated with distant metastasis in gastric cancer and chemoresistance. Anticancer Research 36 (3), pp.1295-1304.
Thesis
- Satherley, L. 2017. The role of DOK7 and its variants in colorectal cancer. PhD Thesis , Cardiff University.
Research
I am a Registrar in General Surgery and have taken time out of my clinical training to undertake a PhD investigating the role of Dok proteins in colorectal cancer. I graduated from UWCM in 2005 with MBBCh and an intercalated BSc in Exercise Sciences. Since joining CCMRC in 2013, I have gained experience in a wide range of laboratory techniques, completed a PGCert in Biomedical Research, presented my research at national and international conferences and spent six weeks on a clinical and academic exchange trip to Beijing. I have really enjoyed working in the Institute alongside scientists and clinicians from all over the world and have found everyone to be very supportive and friendly.