Publication
2017
- Chen, G. et al. 2017. The downstream of tyrosine kinase 7 is reduced in lung cancer and is associated with poor survival of patients with lung cancer. Oncology Reports 37(5), pp. 2695-2701. (10.3892/or.2017.5538)
- Liu, Y. et al. 2017. Psoriasin promotes invasion, aggregation and survival of pancreatic cancer cells; association with disease progression. International Journal of Oncology 50(5), pp. 1491-1500. (10.3892/ijo.2017.3953)
- Cai, S. et al. 2017. Expression of phospholipase C isozymes in human breast cancer and their clinical significance. Oncology Reports 37(3), pp. 1707-1715. (10.3892/or.2017.5394)
- Li, J. et al. 2017. Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells. Oncotarget (10.18632/oncotarget.15439)
- Satherley, L. 2017. The role of DOK7 and its variants in colorectal cancer. PhD Thesis, Cardiff University.
2016
- Malik, M. F. A., Satherley, L., Davies, E., Ye, L. and Jiang, W. G. 2016. Expression of semaphorin 3C in breast cancer and its impact on adhesion and invasion of breast cancer cells. Anticancer Research 36(3), pp. 1281-1286.
- Shao, S. et al. 2016. Reduced RanBPM expression is associated with distant metastasis in gastric cancer and chemoresistance. Anticancer Research 36(3), pp. 1295-1304.
- Satherley, L., Sun, P. H., Ke, J., Mason, M. D., Hargest, R., Jiang, W. G. and Ye, L. 2016. Prostate Apoptosis Response-4 (PAR4) suppresses growth and invasion of breast cancer cells and is positively associated with patient survival. Anticancer Research 36(3), pp. 1227-1236.
- Jiang, W. G. et al. 2016. Effects of YangZheng XiaoJi on the migration and growth of lung cancer cells, by targeting the Hepatocyte Growth Factor Receptor-Epidermal Growth Factor Receptor (HGFR-EGFR) transactivation [Abstract]. European Journal of Cancer 51(S3), pp. S642-S642., article number: 3117. (10.1016/S0959-8049(16)31758-0)
2015
- Li, J., Ye, L., Sun, P., Satherley, L., Hargest, R., Zhang, Z. and Jiang, W. G. 2015. MTA1 is up-regulated in colorectal cancer and is inversely correlated with lymphatic metastasis. Cancer Genomics and Proteomics 12(6), pp. 339-346.
- Satherley, L., Ye, L., Hargest, R. and Jiang, W. G. 2015. Downstream of tyrosine kinase 7 (DOK7) variant expression and function in human colorectal cancer [Abstract]. European Journal of Cancer 51(S3), pp. S27. (10.1016/S0959-8049(15)30004-6)
- Jiang, W. G. et al. 2015. 3117 Effects of YangZheng XiaoJi on the migration and growth of lung cancer cells, by targeting the Hepatocyte Growth Factor Receptor-Epidermal Growth Factor Receptor (HGFR-EGFR) transactivation. European Journal of Cancer 51(Supp 1), pp. S642. (10.1016/S0959-8049(16)31758-0)
- Jiang, W. G. et al. 2015. YangZheng XiaoJi exerts anti-tumour growth effects by antagonising the effects of HGF and its receptor, cMET, in human lung cancer cells. Journal of Translational Medicine 13, article number: 280. (10.1186/s12967-015-0639-1)
- Jiang, W. et al. 2015. Expression of Sonic Hedgehog (SHH) in human lung cancer and the impact of YangZheng XiaoJi on SHH-mediated biological function of lung cancer cells and tumor growth.. Anticancer Research 35(3), pp. 1321-1331.
- Satherley, L., Jiang, W. G., Hargest, R., Torkington, J. and Davies, M. 2015. Expression of lymphangiogenic factors Vegf-C and Vegf-D and impact of Vegf-D knockout on tubule formation in human colorectal cancer [Abstract]. British Journal of Surgery 102(s1), pp. 8-8., article number: 700. (10.1002/bjs.9735)
2014
- Satherley, L., Ye, L., Hargest, R. and Jiang, W. G. 2014. DOK7 expression in colorectal cancer cells and association with clinical and prognostic outcome [Abstract]. British Journal of Surgery 101(S4), pp. 12., article number: O34. (10.1002/bjs.9508)
Articles
- Chen, G. et al. 2017. The downstream of tyrosine kinase 7 is reduced in lung cancer and is associated with poor survival of patients with lung cancer. Oncology Reports 37(5), pp. 2695-2701. (10.3892/or.2017.5538)
- Liu, Y. et al. 2017. Psoriasin promotes invasion, aggregation and survival of pancreatic cancer cells; association with disease progression. International Journal of Oncology 50(5), pp. 1491-1500. (10.3892/ijo.2017.3953)
- Cai, S. et al. 2017. Expression of phospholipase C isozymes in human breast cancer and their clinical significance. Oncology Reports 37(3), pp. 1707-1715. (10.3892/or.2017.5394)
- Li, J. et al. 2017. Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells. Oncotarget (10.18632/oncotarget.15439)
- Malik, M. F. A., Satherley, L., Davies, E., Ye, L. and Jiang, W. G. 2016. Expression of semaphorin 3C in breast cancer and its impact on adhesion and invasion of breast cancer cells. Anticancer Research 36(3), pp. 1281-1286.
- Shao, S. et al. 2016. Reduced RanBPM expression is associated with distant metastasis in gastric cancer and chemoresistance. Anticancer Research 36(3), pp. 1295-1304.
- Satherley, L., Sun, P. H., Ke, J., Mason, M. D., Hargest, R., Jiang, W. G. and Ye, L. 2016. Prostate Apoptosis Response-4 (PAR4) suppresses growth and invasion of breast cancer cells and is positively associated with patient survival. Anticancer Research 36(3), pp. 1227-1236.
- Jiang, W. G. et al. 2016. Effects of YangZheng XiaoJi on the migration and growth of lung cancer cells, by targeting the Hepatocyte Growth Factor Receptor-Epidermal Growth Factor Receptor (HGFR-EGFR) transactivation [Abstract]. European Journal of Cancer 51(S3), pp. S642-S642., article number: 3117. (10.1016/S0959-8049(16)31758-0)
- Li, J., Ye, L., Sun, P., Satherley, L., Hargest, R., Zhang, Z. and Jiang, W. G. 2015. MTA1 is up-regulated in colorectal cancer and is inversely correlated with lymphatic metastasis. Cancer Genomics and Proteomics 12(6), pp. 339-346.
- Satherley, L., Ye, L., Hargest, R. and Jiang, W. G. 2015. Downstream of tyrosine kinase 7 (DOK7) variant expression and function in human colorectal cancer [Abstract]. European Journal of Cancer 51(S3), pp. S27. (10.1016/S0959-8049(15)30004-6)
- Jiang, W. G. et al. 2015. 3117 Effects of YangZheng XiaoJi on the migration and growth of lung cancer cells, by targeting the Hepatocyte Growth Factor Receptor-Epidermal Growth Factor Receptor (HGFR-EGFR) transactivation. European Journal of Cancer 51(Supp 1), pp. S642. (10.1016/S0959-8049(16)31758-0)
- Jiang, W. G. et al. 2015. YangZheng XiaoJi exerts anti-tumour growth effects by antagonising the effects of HGF and its receptor, cMET, in human lung cancer cells. Journal of Translational Medicine 13, article number: 280. (10.1186/s12967-015-0639-1)
- Jiang, W. et al. 2015. Expression of Sonic Hedgehog (SHH) in human lung cancer and the impact of YangZheng XiaoJi on SHH-mediated biological function of lung cancer cells and tumor growth.. Anticancer Research 35(3), pp. 1321-1331.
- Satherley, L., Jiang, W. G., Hargest, R., Torkington, J. and Davies, M. 2015. Expression of lymphangiogenic factors Vegf-C and Vegf-D and impact of Vegf-D knockout on tubule formation in human colorectal cancer [Abstract]. British Journal of Surgery 102(s1), pp. 8-8., article number: 700. (10.1002/bjs.9735)
- Satherley, L., Ye, L., Hargest, R. and Jiang, W. G. 2014. DOK7 expression in colorectal cancer cells and association with clinical and prognostic outcome [Abstract]. British Journal of Surgery 101(S4), pp. 12., article number: O34. (10.1002/bjs.9508)
Thesis
- Satherley, L. 2017. The role of DOK7 and its variants in colorectal cancer. PhD Thesis, Cardiff University.
Research
I am a Registrar in General Surgery and have taken time out of my clinical training to undertake a PhD investigating the role of Dok proteins in colorectal cancer. I graduated from UWCM in 2005 with MBBCh and an intercalated BSc in Exercise Sciences. Since joining CCMRC in 2013, I have gained experience in a wide range of laboratory techniques, completed a PGCert in Biomedical Research, presented my research at national and international conferences and spent six weeks on a clinical and academic exchange trip to Beijing. I have really enjoyed working in the Institute alongside scientists and clinicians from all over the world and have found everyone to be very supportive and friendly.