Dr Melissa Wright
(she/her)
Postdoctoral Research Associate
School of Physics and Astronomy
- WrightME@cardiff.ac.uk
- Cardiff University Brain Research Imaging Centre, Maindy Road, Cardiff, CF24 4HQ
- Available for postgraduate supervision
Overview
Research Overview
My research focuses on vascular health and functioning across the brain and eye and how this interacts with hormonal profile. In particular, I am interested in woman's health and under-researched groups. My current projects focus on understanding how the fluctuations of hormones across a menstrual cycle influence vascular health, and how vascular functioning is impacted in conditions such as Polycystic Ovary Syndrome (PCOS).
Publication
2023
- Talbot, J. S. et al. 2023. Cerebral blood flow and cerebrovascular reactivity are modified by maturational stage and exercise training status during youth. Experimental Physiology 108(12), pp. 1500-1515. (10.1113/ep091279)
- Wright, M. E. and Murphy, K. 2023. A mini-review of the evidence for cerebrovascular changes following gender-affirming hormone replacement therapy and a call for increased focus on cerebrovascular transgender health. Frontiers in Human Neuroscience 17, article number: 1303871. (10.3389/fnhum.2023.1303871)
2021
- Wright, M. 2021. An investigation into the contribution of receptive fields in the visual cortex to altered perimetric spatial summation in glaucoma. PhD Thesis, Cardiff University.
2020
- Wright, M. E. 2020. Busting the myths of functional magnetic resonance imaging (fMRI). PsyPAG Quarterly 1(114) (10.53841/bpspag.2020.1.114.9)
2018
- Wright, M. E. and Wise, R. G. 2018. Can blood oxygenation level dependent functional magnetic resonance imaging be used accurately to compare older and younger populations? A mini literature review. Frontiers in Aging Neuroscience 10, article number: 371. (10.3389/fnagi.2018.00371)
Articles
- Talbot, J. S. et al. 2023. Cerebral blood flow and cerebrovascular reactivity are modified by maturational stage and exercise training status during youth. Experimental Physiology 108(12), pp. 1500-1515. (10.1113/ep091279)
- Wright, M. E. and Murphy, K. 2023. A mini-review of the evidence for cerebrovascular changes following gender-affirming hormone replacement therapy and a call for increased focus on cerebrovascular transgender health. Frontiers in Human Neuroscience 17, article number: 1303871. (10.3389/fnhum.2023.1303871)
- Wright, M. E. 2020. Busting the myths of functional magnetic resonance imaging (fMRI). PsyPAG Quarterly 1(114) (10.53841/bpspag.2020.1.114.9)
- Wright, M. E. and Wise, R. G. 2018. Can blood oxygenation level dependent functional magnetic resonance imaging be used accurately to compare older and younger populations? A mini literature review. Frontiers in Aging Neuroscience 10, article number: 371. (10.3389/fnagi.2018.00371)
Thesis
- Wright, M. 2021. An investigation into the contribution of receptive fields in the visual cortex to altered perimetric spatial summation in glaucoma. PhD Thesis, Cardiff University.
Research
My postdoctoral research focuses on vascular health and functioning across the brain and eye and how this interacts with the hormonal profile (e.g., levels of oestrogen, progesterone, testosterone). In particular, I am interested in woman's health and under-researched groups. My current projects focus on understanding how the fluctuations of hormones across a menstrual cycle influence vascular health, and how vascular functioning is impacted in conditions such as Polycystic Ovary Syndrome (PCOS).
I am currently working within Professor Kevin Murphy's lab, but also work with collaborators in Cardiff Metropolitan University, The University of Edinburgh, and the University of California, Los Angeles.
Funding and Awards
- ITPA - Translational Knowledge Exchange and Training Award (TKET) 2022 - £1281
- Guarantors of Brain travel grant (for travel to OHBM 2022) - £500
- PsyPAG research grant 2019 (for participant and equipment costs) - £300
- Guarantors of Brain travel grant (for travel to OHBM 2019) - £465
- British Chapter ISMRM Student Stipend 2018 - £75
- Imaging and Perimetry Society (IPS) 2018 travel grant - $1,000
- Masters Excellence Scholarship 2015; Cardiff University - £3,000 tuition discount
- British Psychological Society Prize for highest graded dissertation 2015; Aston University
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In my PhD, I used fMRI (3T and 7T) and psychophysics to investigate cortical reorganisation in glaucoma, as well as relationships between the functional architecture of the eye and brain. I was funded by a Fight for Sight PhD studentship.
PhD Research Team
Dr Tony Redmond (Primary supervisor: School of Optometry and Vision sciences, Cardiff University)
Prof Krishna Singh (Second supervisor: CUBRIC, School of Psychology, Cardiff University)
Prof Simon Rushton (Third supervisor: School of Psychology, Cardiff University)
Prof James E Morgan (Collaborator: School of Optometry and Vision sciences, Cardiff University)
Prof Tom Margrain (Collaborator: School of Optometry and Vision sciences, Cardiff University)
Dr Fergal A Ennis (Collaborator: School of Optometry and Vision sciences, Cardiff University)
Biography
Educational and Professional Qualifications
2022 – Advanced fellow in Higher Education (AFHEA)
2016 – 2021: PhD: Cardiff University -Vision Sciences and Neuroimaging
Title: Changes in the visual cortex in glaucoma and a possible role in visual recovery: an fMRI study.
Supervisors: Tony Redmond, Krish D Singh, Simon K Rushton
2015 – 2016: MSc Neuroimaging: Methods and applications: Cardiff University
2011 – 2015: BSc Psychology with integrated placement: Aston University
Committees and reviewing
- Committee member on the Science committee for the Society for Endocrinology (SfE; 2024-2028).
- I have undertaken editorial roles for Frontiers (research topic editor) and for the SfE public engagement site, You and Your Hormones (content editor). I have also completed scientific peer reviews for the journal Cortex and for ISMRM.
- I am a LGBT+ advocate for the Institute of Physics LGBT+ network, which involves editing the quarterly newsletter to all network members.
Research themes
Specialisms
- Endocrinology
- Neuroimaging