![Sarah Youde FHEA CSci](https://profiles-cardiff.imgix.net/attachments/1695?w=200&h=200&auto=format&crop=faces&fit=crop&q=90")
Dr Sarah Youde
(she/her)
FHEA CSci
Teams and roles for Sarah Youde
Technical Specialist
Overview
- I am a technnical speciliast providing support for the division of Infection and Immunity, School of Medicine.
- I manage health and safety requirements for the facilities ensuring current legislation is followed.
- I ensure equipment is maintained to ensure the safety of users.
Publication
2016
- Sadaghiani, L. et al. 2016. Growth factor liberation and DPSCs response following dentine conditioning. Journal of Dental Research 95 (11), pp.1298-1307. (10.1177/0022034516653568)
- Young, F. I. et al. 2016. Clonal heterogeneity in the neuronal and glial differentiation of dental pulp stem/progenitor cells. Stem Cells International 2016 1290561. (10.1155/2016/1290561)
2009
- Waddington, R. J. et al. 2009. Isolation of distinct progenitor stem cell populations from dental pulp. Cells Tissues Organs 189 (1-4), pp.268-274. (10.1159/000151447)
2008
- Roberts, H. C. et al. 2008. Lipopolysaccharide alters decorin and biglycan synthesis in rat alveolar bone osteoblasts: Consequences for bone repair during periodontal disease. European Journal of Oral Sciences 116 (3), pp.207-216. (10.1111/j.1600-0722.2008.00535.x)
- Thomas, K. J. et al., 2008. HPV16 E629-38-specific T cells kill cervical carcinoma cells despite partial evasion of T-cell effector function. International Journal of Cancer 122 (12), pp.2791-2799. (10.1002/ijc.23475)
2006
- McCarthy, C. , Youde, S. J. and Man, S. T. 2006. Definition of an HPV18/45 cross-reactive human T-cell epitope after DNA immunisation of HLA-A2/KB transgenic mice. International Journal of Cancer 118 (10), pp.2514-21. (10.1002/ijc.21643)
2005
- Youde, S. J. et al. 2005. Cross-typic specificity and immunotherapeutic potential of a human HPV16 E7-specific CTL line. International Journal of Cancer 114 (4), pp.606-12. (10.1002/ijc.20779)
- Hill, S. C. et al., 2005. Activation of CD40 in cervical carcinoma cells facilitates CTL responses and augments chemotherapy-induced apoptosis. Journal of Immunology 174 (1), pp.41-50.
2000
- Youde, S. J. et al. 2000. Use of fluorogenic histocompatibility leukocyte antigen-A*0201/HPV 16 E7 peptide complexes to isolate rare human cytotoxic T-lymphocyte-recognizing endogenous human papillomavirus antigens. Cancer Research 60 (2), pp.365-371.
1998
- Youde, S. J. et al. 1998. Stress protein expression in primary and immortalized cultures of human thyroid cells: A model system for the study of stress proteins in the pathogenesis of autoimmune thyroid disease. Cell Stress & Chaperones 3 (2), pp.89-93.
1996
- Youde, S. J. and Parkes, A. B. 1996. Stress-induced expression of a thyroid peroxidase-like protein in cultured human thyroid cells. Autoimmunity 23 (4), pp.279-282.
Articles
- Sadaghiani, L. et al. 2016. Growth factor liberation and DPSCs response following dentine conditioning. Journal of Dental Research 95 (11), pp.1298-1307. (10.1177/0022034516653568)
- Young, F. I. et al. 2016. Clonal heterogeneity in the neuronal and glial differentiation of dental pulp stem/progenitor cells. Stem Cells International 2016 1290561. (10.1155/2016/1290561)
- Waddington, R. J. et al. 2009. Isolation of distinct progenitor stem cell populations from dental pulp. Cells Tissues Organs 189 (1-4), pp.268-274. (10.1159/000151447)
- Roberts, H. C. et al. 2008. Lipopolysaccharide alters decorin and biglycan synthesis in rat alveolar bone osteoblasts: Consequences for bone repair during periodontal disease. European Journal of Oral Sciences 116 (3), pp.207-216. (10.1111/j.1600-0722.2008.00535.x)
- Thomas, K. J. et al., 2008. HPV16 E629-38-specific T cells kill cervical carcinoma cells despite partial evasion of T-cell effector function. International Journal of Cancer 122 (12), pp.2791-2799. (10.1002/ijc.23475)
- McCarthy, C. , Youde, S. J. and Man, S. T. 2006. Definition of an HPV18/45 cross-reactive human T-cell epitope after DNA immunisation of HLA-A2/KB transgenic mice. International Journal of Cancer 118 (10), pp.2514-21. (10.1002/ijc.21643)
- Youde, S. J. et al. 2005. Cross-typic specificity and immunotherapeutic potential of a human HPV16 E7-specific CTL line. International Journal of Cancer 114 (4), pp.606-12. (10.1002/ijc.20779)
- Hill, S. C. et al., 2005. Activation of CD40 in cervical carcinoma cells facilitates CTL responses and augments chemotherapy-induced apoptosis. Journal of Immunology 174 (1), pp.41-50.
- Youde, S. J. et al. 2000. Use of fluorogenic histocompatibility leukocyte antigen-A*0201/HPV 16 E7 peptide complexes to isolate rare human cytotoxic T-lymphocyte-recognizing endogenous human papillomavirus antigens. Cancer Research 60 (2), pp.365-371.
- Youde, S. J. et al. 1998. Stress protein expression in primary and immortalized cultures of human thyroid cells: A model system for the study of stress proteins in the pathogenesis of autoimmune thyroid disease. Cell Stress & Chaperones 3 (2), pp.89-93.
- Youde, S. J. and Parkes, A. B. 1996. Stress-induced expression of a thyroid peroxidase-like protein in cultured human thyroid cells. Autoimmunity 23 (4), pp.279-282.
Teaching
- I lecture on the Tissue Engineering and Regenerative medicine MSc course run by Cardiff University Dental School.
- I have been award an AdvancedHE fellowship.
Biography
My current position is techncal specilaist in the divsion of Infection and Immunity, School of Medicine.
University duties
- I am a member of the university Genetic Modification and Biological Agents Safety Committee.
- I am a member of the university Biobank review committee.
- I am a member of the team organising the Cardiff University Technical Staff Conference.
- I am a member of the University Technical Services Working group.
PhD
The role of stress proteins in the initiation of autoimmune thyroid disease. Cardiff University 1997.
Degree:
B.Sc. (Hons.) Biomedical Sciences I Class Cardiff University 1992.
PD
Honours and awards
- Nominated for an outstanding contibution award, 2024, as part of the team organising the Cardiff University Technical Conference.
- I graduated from the Herschel Programme for Women in Technical Leadership, 2022.
- I won the William O'Grady prize for technicians 2018, part of Cardiff University's Celebrating Excellence Awards.
- I was nominated for the Royal Society of Biology HE Bioscience Technician of the Year 2018.
Professional memberships
- I am a registered Chartered Scientist.
- I am a member of the IST.
Academic positions
Committees and reviewing
- I am a member of the committee organising the IST conference for 2023.
Contact Details
[email protected]
+44 29225 12081
Sir Geraint Evans Cardiovascular Research Building, Floor 2nd, University Hospital of Wales, Heath Park, Cardiff, CF14 4XN
+44 29225 12081
Sir Geraint Evans Cardiovascular Research Building, Floor 2nd, University Hospital of Wales, Heath Park, Cardiff, CF14 4XN
Research themes
Specialisms
- cell culture