Yr Athro Rachel Errington

2026

• Papachristos, M. G. et al. 2026. Spatial characterization of prostate cancer microenvironment with DRAQ5&Eosin fluorescence imaging and quantitative feature identification. Journal of Pathology Informatics 100746. (10.1016/j.jpi.2026.100746)
• Papachristos, M. G. et al. 2026. Prostate cancer tissue mapping and stratification using DRAQ5 and Eosin fluorescent labels integrated with AI classification and segmentation algorithms. PLoS ONE 21 (3) e0345014. (10.1371/journal.pone.0345014)

2025

• Mehmood, A. et al., 2025. Association of DDR pathway proteins and breast cancer risk in a Pakistani population. Future Oncology 21 (28), pp.3655-3665. (10.1080/14796694.2025.2581508)

2023

• Ahmad, F. et al. 2023. Quantifying the microstructural and biomechanical changes in the porcine ventricles during growth and remodelling. Acta Biomaterialia 171 , pp.166-192. (10.1016/j.actbio.2023.09.044)
• Dumcius, P. et al. 2023. Dual-Wave Acoustofluidic Centrifuge for Ultrafast Concentration of Nanoparticles and Extracellular Vesicles. Small 19 (35) 2300390. (10.1002/smll.202300390)
• Dumcius, P. et al. 2023. Dual-wave acoustofluidic centrifuge for ultrafast concentration of nanoparticles and extracellular vesicles (small 35/2023) [Inside front cover]. Small 19 (35) 2370274. (10.1002/smll.202370274)

2021

• de Almeida, A. et al. 2021. Aquaglyceroporin-3’s expression and cellular localization is differentially modulated by hypoxia in prostate cancer cell lines. Cells 10 (4) 838. (10.3390/cells10040838)
• Evans, L. et al. 2021. Macrophage plasticity and function in the lung tumour microenvironment revealed in 3D heterotypic spheroid and explant models. Biomedicines 9 (3) 302. (10.3390/biomedicines9030302)
• Edmunds, G. L. et al., 2021. Dog breeds and body conformations with predisposition to osteosarcoma in the UK: a case-control study. Canine Medicine and Genetics 8 2. (10.1186/s40575-021-00100-7)

2020

• Karuna, A. et al. 2020. Quantitative imaging of B1 cyclin expression across the cell cycle using green fluorescent protein tagging and epi-fluorescence. Cytometry Part A 97 (10), pp.1066-1072. (10.1002/cyto.a.24038)
• Moses, R. L. et al. 2020. Novel epoxy-tiglianes stimulate skin keratinocyte wound healing responses and re-epithelialization via protein kinase C activation. Biochemical Pharmacology 178 114048. (10.1016/j.bcp.2020.114048)
• Xu, L. et al., 2020. Design of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling. Journal of Extracellular Vesicles 9 (1) 1779458. (10.1080/20013078.2020.1779458)
• Mikhaylov, R. et al. 2020. Development and characterisation of acoustofluidic devices using detachable electrodes made from PCB. Lab on a Chip 20 (10), pp.1807-1814. (10.1039/C9LC01192G)

2019

• Icha, J. et al., 2019. Phototoxicity in live fluorescence imaging understanding, quantifying and minimizing it. Cytometry Part A 95 (6), pp.634-636. (10.1002/cyto.a.23777)
• Karuna, A. et al. 2019. Label-free volumetric quantitative imaging of human osteosarcoma cells by hyperspectral coherent anti-Stokes Raman scattering. Presented at: SPIE BIOS San Francisco, California, US 2-7 Feb 2019. Multiphoton Microscopy in the Biomedical Sciences XIX. Vol. 10882.Proceedings of SPIE Bellingham, Washington: SPIE. , pp.108821P. (10.1117/12.2510277)
• Karuna, A. et al. 2019. Label-free volumetric quantitative imaging of the human somatic cell division by hyperspectral coherent anti-Stokes Raman scattering. Analytical Chemistry 91 (4), pp.2813-2821. (10.1021/acs.analchem.8b04706)

2018

• Jordan, L. A. et al. 2018. Inhibition of CCL3 abrogated precursor cell fusion and bone erosions in human osteoclast cultures and murine collagen-induced arthritis. Rheumatology 57 (11), pp.2042-2052. (10.1093/rheumatology/key196)
• Johnson, C. E. et al. 2018. Loss of tuberous sclerosis complex 2 sensitizes tumors to nelfinavir−bortezomib therapy to intensify endoplasmic reticulum stress-induced cell death. Oncogene 37 , pp.5913-5925. (10.1038/s41388-018-0381-2)
• McCann, H. et al. 2018. Energy stress-mediated cytotoxicity in tuberous sclerosis complex 2-deficient cells with nelfinavir and mefloquine treatment. Cancers 10 (10) 375. (10.3390/cancers10100375)
• Smith, P. J. , Darzynkiewicz, Z. and Errington, R. J. 2018. Nuclear cytometry and chromatin organization. Cytometry Part A 93 (8), pp.771-784. (10.1002/cyto.a.23521)
• Stephens, N. , Khan, I. and Errington, R. 2018. Analysing the role of virtualisation and visualisation on interdisciplinary knowledge exchange in stem cell research processes. Palgrave Communications 4 (1), pp.-. 78. (10.1057/s41599-018-0126-4)
• Yeung, V. et al. 2018. Rab35-dependent extracellular nanovesicles are required for induction of tumour supporting stroma. Nanoscale 10 (18), pp.8547-8559. (10.1039/C8NR02417K)
• Errington, R. J. et al. 2018. Probing cytochrome P450 bioactivation and fluorescent properties with morpholinyl-tethered anthraquinones. Bioorganic and Medicinal Chemistry Letters 28 (8), pp.1274-1277. (10.1016/j.bmcl.2018.03.040)

2017

• Nesbitt, H. et al., 2017. The unidirectional hypoxia-activated prodrug OCT1002 inhibits growth and vascular development in castrate-resistant prostate tumors. Prostate 77 (15), pp.1539-1547. (10.1002/pros.23434)
• Nesbitt, H. et al., 2017. Targeting hypoxic prostate tumours using the novel hypoxia-activated prodrug OCT1002 inhibits expression of genes associated with malignant progression. Clinical Cancer Research 23 (7), pp.1797-1808. (10.1158/1078-0432.CCR-16-1361)
• Dunlop, E. A. et al. 2017. Targeting protein homeostasis with nelfinavir/salinomycin dual therapy effectively. Oncotarget (10.18632/oncotarget.16232)
• Pretorius, A. J. , Khan, I. A. and Errington, R. J. 2017. A survey of visualization for live cell imaging. Computer Graphics Forum 36 (1), pp.46-63. (10.1111/cgf.12784)

2015

• Colombo, J. S. et al., 2015. A 3D ex vivo mandible slice system for longitudinal culturing of transplanted dental pulp progenitor cells. Cytometry Part A 87 (10), pp.921-928. (10.1002/cyto.a.22680)

2014

• Khan, I. et al. 2014. ProtocolNavigator: emulation-based software for the design, documentation and reproduction biological experiments. Bioinformatics 30 (23), pp.3440-3442. (10.1093/bioinformatics/btu554)
• Johnson, C. et al. 2014. Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine. Molecular Oncology 9 (3), pp.675-688. (10.1016/j.molonc.2014.11.005)

2013

• Colmont, C. S. et al. 2013. Human basal cell carcinoma tumor-initiating cells are resistant to etoposide [Letter]. Journal of Investigative Dermatology 134 (3), pp.867-870. (10.1038/jid.2013.377)
• Al-Saraireh, Y. et al., 2013. Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration. PLoS ONE 8 (8), pp.e73366. (10.1371/journal.pone.0073366)
• Errington, R. J. et al. 2013. Time-lapse microscopy approaches to track cell cycle and lineage progression at the single-cell level. Current Protocols in Cytometry 64 (12.4)(10.1002/0471142956.cy1204s64)
• Becker, H. et al., 2013. Multivariate analysis of apoptotic markers versus cell cycle phase in living human cancer cells by microfluidic cytometry. Proceedings of SPIE 8615 , pp.86150W. (10.1117/12.2001474)
• Akagi, J. et al., 2013. Real-time cell viability assays using a new anthracycline derivative DRAQ7®. Cytometry Part A 83A (2), pp.227-234. (10.1002/cyto.a.22228)
• Mart, R. J. et al. 2013. BH3 helix-derived biophotonic nanoswitches regulate cytochrome c release in permeabilised cells. Molecular BioSystems 9 (11), pp.2597-2603. (10.1039/c3mb70246d)
• Smith, P. , Falconer, R. and Errington, R. 2013. Micro-community cytometry: sensing changes in cell health and glycoconjugate expression by imaging and flow cytometry. Journal of Microscopy 251 (2), pp.113-122. (10.1111/jmi.12060)
• Smith, P. J. et al. 2013. NCAM polysialylation during adherence transitions: live cell monitoring using an antibody-mimetic EGFP-endosialidase and the viability dye DRAQ7. Cytometry Part A 83A (7), pp.659-671. (10.1002/cyto.a.22306)
• Smith, P. J. et al. 2013. Kinetic analysis of intracellular Hoechst 33342-DNA interactions by flow cytometry: misinterpretation of side population status?. Cytometry Part A 83A (1), pp.161-169. (10.1002/cyto.a.22224)

2011

• Fricke, T. et al. 2011. Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins. Bioconjugate Chemistry 22 (9), pp.1763-1767. (10.1021/bc200338u)
• Atari, M. I. et al., 2011. Kinetic modelling of the role of the aldehyde dehydrogenase enzyme and the breast cancer resistance protein in drug resistance and transport. Computer Methods and Programs in Biomedicine 104 (2), pp.93-103. (10.1016/j.cmpb.2010.06.008)
• Khan, I. A. et al. 2011. Interoperability of time series cytometric data: A cross platform approach for modeling tumor heterogeneity. Cytometry Part A 79A (3), pp.214-226. (10.1002/cyto.a.21023)
• Rees, P. et al., 2011. A transfer function approach to measuring cell inheritance. BMC Systems Biology 5 31. (10.1186/1752-0509-5-31)
• Summers, H. D. et al., 2011. Statistical analysis of nanoparticle dosing in a dynamic cellular system. Nature Nanotechnology 6 (3), pp.170-174. (10.1038/nnano.2010.277)

2010

• Errington, R. J. et al. 2010. Single cell nanoparticle tracking to model cell cycle dynamics and compartmental inheritance. Cell Cycle 9 (1), pp.121-130. (10.4161/cc.9.1.10246)
• Brown, M. R. et al. 2010. Flow-based cytometric analysis of cell cycle via simulated cell populations. PLOS Computational Biology 6 (4) e1000741. (10.1371/journal.pcbi.1000741)
• Brown, M. R. et al. 2010. Long-term time series analysis of quantum dot encoded cells by deconvolution of the autofluorescence signal. Cytometry Part A 77A (10), pp.925-932. (10.1002/cyto.a.20936)
• Johnstone, S. R. et al. 2010. Enhanced Connexin 43 Expression Delays Intra-Mitoitc Duration and Cell Cycle Traverse Independently of Gap Junction Channel Function. Journal of Cellular Biochemistry 110 (3), pp.772-782. (10.1002/jcb.22590)

2009

• Holton, M. D. et al., 2009. Stroboscopic fluorescence lifetime imaging. Optics Express 17 (7), pp.5205-5216. (10.1364/OE.17.005205)
• Johnstone, S. J. et al., 2009. Enhanced Connexin 43 expression mediates cell proliferation and migration independent of connexin mediated communication [Abstract]. Journal of Investigative Dermatology 129 (S2), pp.S82. (10.1038/jid.2009.232)
• Silvestre, O. et al. 2009. Hollow fiber: a biophotonic implant for live cells. Presented at: Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII San Jose, CA, USA 26-28 January 2009. Published in: Farkas, D. L. , Nicolau, D. V. and Leif, R. C. eds. Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII. Proceedings of the SPIE Vol. 7182. Bellingham, WA: SPIE(10.1117/12.809391)
• Smith, P. J. et al. 2009. Microtrench and tumour proliferation assay. WO/2009/095666[Patent]
• Smith, P. J. et al. 2009. ABCG2-Associated Resistance to Hoechst 33342 and Topotecan in a Murine Cell Model with Constitutive Expression of Side Population Characteristics. Cytometry Part A 75A (11), pp.924-933. (10.1002/cyto.a.20800)
• Smith, P. J. , Khan, I. A. and Errington, R. J. 2009. Cytomics and cellular informatics - coping with asymmetry and heterogeneity in biological systems. Drug Discovery Today 14 (5-6), pp.271-277. (10.1016/j.drudis.2008.11.012)

2008

• Chappell, M. J. et al. 2008. A coupled drug kinetics-cell cycle model to analyse the response of human cells to intervention by topotecan. Computer Methods and Programs in Biomedicine 89 (2), pp.169-178. (10.1016/j.cmpb.2007.11.002)
• Cheung, S. Y. A. et al., 2008. Exploration of the intercellular heterogeneity of topotecan uptake into human breast cancer cells through compartmental modelling. Mathematical Biosciences 213 (2), pp.119-134. (10.1016/j.mbs.2008.03.008)
• Smith, P. J. and Errington, R. J. 2008. Dissecting the Cell Cycle: Loss of Genomic Integrity and Escape from Senescence [Abstract]. Cytometry Part B Clinical Cytometry 74B (6), pp.390. (10.1002/cyto.b.20462)
• Smith, P. J. , Patterson, L. and Errington, R. J. 2008. Gel formulations and uses thereof. 20080182287[Patent]
• Smith, P. J. et al. 2008. Impact of overexpression of metallothionein-1 on cell cycle progression and zinc toxicity. American Journal of Physiology - Cell Physiology 295 (5), pp.C1399-C1408. (10.1152/ajpcell.00342.2008)
• Summers, H. D. et al., 2008. Cytometric biochips with optically active surfaces for spatial engineering of fluorescence excitation. Presented at: Microfluidics, BioMEMS, and Medical Microsystems VI San Jose, CA, USA 21-22 January 2008. Published in: Wang, W. and Vauchier, C. eds. Microfluidics, BioMEMS, and Medical Microsystems VI (Proceedings Volume). Proceedings of the SPIE Vol. 6886. Bellingham, WA: SPIE(10.1117/12.763645)
• Summers, H. D. et al., 2008. Cell-population tracking using quantum dots in flow cytometry. Presented at: Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V San Jose, CA, USA 21-23 February 2008. Published in: Cartwright, A. N. and Nicolau, D. V. eds. Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V. Proceedings of the SPIE Vol. 6865. Bellingham, WA: SPIE. , pp.68650L. (10.1117/12.763602)
• Vojnovic, B. et al., 2008. Detecting objects. WO/2008/090330[Patent]

2007

• Matthews, D. R. et al. 2007. A fluorescence biochip with a plasmon active surface. Presented at: Plasmonics in Biology and Medicine IV San Jose, CA, USA 20 January 2007. Published in: Vo-Dinh, T. and Lakowicz, J. R. eds. Plasmonics in Biology and Medicine IV. Proceedings of SPIE Vol. 6450. Bellingham, WA: SPIE. , pp.645006. (10.1117/12.698948)
• Morris, D. et al., 2007. Development of an optical biochip for the analysis of cell environment sensitivity. Presented at: Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V San Jose, CA, USA 20 January 2007. Published in: Farkas, D. L. , Leif, R. C. and Nicolau, D. V. eds. Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V. Proceedings of SPIE Vol. 6441. Bellingham, WA: SPIE. , pp.64410V. (10.1117/12.700052)
• Njoh, K. et al. 2007. Live cell tracking on an optical biochip platform. Presented at: Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V San Jose, CA, USA 20 January 2007. Published in: Farkas, D. L. , Leif, R. C. and Nicolau, D. V. eds. Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V. Proceedings of SPIE Vol. 6441. Bellingham, WA: SPIE. , pp.64410X. (10.1117/12.698935)
• Chong, E. Z. et al., 2007. Development of FRET-Based assays in the Far-Red using CdTe quantum dots. Journal of Biomedicine and Biotechnology 2007 54169. (10.1155/2007/54169)
• Khan, I. A. et al. 2007. ProgeniDB - A novel cell lineage database for generation associated phenotypic behavior in cell-based assays. Cell Cycle 6 (7), pp.868-874. (10.4161/cc.6.7.4045)
• Smith, P. J. et al. 2007. Mitotic bypass via an occult cell cycle phase following DNA topoisomerase II inhibition in p53 functional human tumor cells. Cell Cycle 6 (16), pp.2071-2081. (10.4161/cc.6.16.4585)

2006

• Matthews, D. R. et al. 2006. Technique for Measurement of Fluorescence Lifetime by use of Stroboscopic Excitation and Continuous-Wave Detection. Applied Optics 45 (9), pp.2115-2123. (10.1364/AO.45.002115)
• Njoh, K. L. et al. 2006. Spectral analysis of the DNA targeting bisalkylaminoanthraquinone DRAQ5 in intact living cells. Cytometry Part A 69A (8), pp.805-814. (10.1002/cyto.a.20308)

2005

• Errington, R. J. et al. 2005. Advanced microscopy solutions for monitoring the kinetics and dynamics of drug-DNA targeting in living cells. Advanced Drug Delivery Reviews 57 (10), pp.153-167. (10.1016/j.addr.2004.05.005)
• White, N. and Errington, R. J. 2005. Fluorescence techniques for drug delivery research: theory and practice. Advanced Drug Delivery Reviews 57 (1), pp.17-42. (10.1016/j.addr.2004.08.003)

2004

• Hughes, A. et al. 2004. Endophilin A3 forms filamentous structures that colocalise with microtubules but not with actin filaments. Molecular Brain Research 128 (2), pp.182-192. (10.1016/j.molbrainres.2004.06.016)
• Stephens, P. et al. 2004. Crosslinking and G-protein functions of transglutaminase 2 contribute differentially to fibroblast wound healing responses. Journal of cell science 117 (15), pp.3389-3403. (10.1242/jcs.01188)
• Marquez, N. et al. 2004. Microtubule stress modifies intra-nuclear location of Msh2 in mouse embryonic fibroblasts. Cell Cycle 3 , pp.662-671.

2003

• Marquez, N. et al. 2003. Single cell tracking reveals that Msh2 is a key component of an early-acting DNA damage-activated G2 checkpoint. Oncogene 22 (48), pp.7642-7648. (10.1038/sj.onc.1206876)

2002

• Baker, H. L. et al. 2002. A mathematical model predicts that calreticulin interacts with the endoplasmic reticulum Ca2+-ATPase. Biophysical journal 82 , pp.582-590.
• Oviedo-Orta, E. , Errington, R. J. and Evans, W. H. 2002. Gap junction intercellular communication during lymphocyte transendothelial migration. Cell Biology International 26 (3), pp.253-263. (10.1006/cbir.2001.0840)

2001

• Martin, P. et al., 2001. Multiple pathways in the trafficking and assembly of connexin 26, 32 and 43 into gap junction intercellular communication channels. Journal of Cell Science 114 (21), pp.3845-3855.

2000

• Smith, P. J. et al. 2000. Characteristics of a novel deep red/infrared fluorescent cell-permeant DNA probe, DRAQ5, in intact human cells analyzed by flow cytometry, confocal and multiphoton microscopy. Cytometry 40 (4), pp.280-291. (10.1002/1097-0320(20000801)40:4<280::AID-CYTO4>3.0.CO;2-7)