Mr Ian Boostrom
Teams and roles for Ian Boostrom
Lab Manager, Medical Microbiology Research
Overview
I am a Laboratory Manager in the School of Medicine who also specializes in microbial genomics, nanopore sequencing, and laboratory-to-computational workflows for medical microbiology research. I more broadly support shared laboratory infrastructure, procurement, contracts, training, onboarding, liaising with NHS and Cardiff University estates/management teams, and experimental troubleshooting across a busy medical microbiology research environment.
A central theme of my current work is bridging the gap between complex bioinformatics tools and the practical needs of laboratory researchers, service-adjacent research, and multidisciplinary collaborators brought together by Prof. Brad Spiller. I am particularly interested in helping colleagues make effective use of Cardiff University's excellent supercomputing resources through ARCCA, including through my involvement as a member of the ARCCA Operational User Group.
I am able to engage with a wide range of collaborators by drawing on experience in clinical laboratory settings, international and low-resource contexts, and work involving regulated, clinically significant, and higher-containment microorganisms. While not strictly applicable to UK laboratories, I have long maintained an American Medical Technologists accreditation and strongly support their efforts to enable practical and resilient certification routes for Allied Health Professionals.
My broader interests include antimicrobial resistance, diagnostic microbiology (ESGMD member), Legionella (ESGLI member), pathogen genomics, long-read sequencing, FAIR and reproducible data practices (see Dr. Robert Andrews), advancing resilient and impactful trials (see Dr. Lucy Jones), research infrastructure, and the practical delivery of advanced sequencing methods in shared laboratory environments. I have also become increasingly interested in medical mycology through the privilege of hosting Prof. Lewis White and his research team on our floor at the University Hospital of Wales.
Publication
2026
- Saud, Z. et al. 2026. Discovery of a fungal Tc toxin complex and functional mycoserpin through a novel two-by-two comparative genomics approach. Frontiers in Cellular and Infection Microbiology 16 1800461. (10.3389/fcimb.2026.1800461)
2025
- Sands, K. et al. 2025. Acquisition of Escherichia coli carrying extended-spectrum ß-lactamase and carbapenemase genes by hospitalised children with severe acute malnutrition in Niger. Nature Communications 16 (1) 6751. (10.1038/s41467-025-61718-w)
2024
- Nieto-Rosado, M. et al. 2024. Colonisation of hospital surfaces from low- and middle-income countries by extended spectrum β-lactamase- and carbapenemase-producing bacteria. Nature Communications 15 2758. (10.1038/s41467-024-46684-z)
- Portal, E. A. R. et al. 2024. Characterisation of colistin resistance in Gram-negative microbiota of pregnant women and neonates in Nigeria. Nature Communications 15 (1) 2302. (10.1038/s41467-024-45673-6)
2023
- Farzana, R. et al. 2023. Genomic insights into the mechanism of carbapenem resistance dissemination in Enterobacterales from a tertiary public heath setting in South Asia. Clinical Infectious Diseases 76 (1), pp.119-133. (10.1093/cid/ciac287)
2022
- Carvalho, M. J. et al., 2022. Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low- and middle-income countries. Nature Microbiology 7 , pp.1337-1347. (10.1038/s41564-022-01184-y)
- Acolatse, J. E. E. et al., 2022. Environmental surveillance of ESBL and carbapenemase-producing gram-negative bacteria in a Ghanaian Tertiary Hospital. Antimicrobial Resistance and Infection Control 11 (1) 49. (10.1186/s13756-022-01090-2)
- Boostrom, I. et al. 2022. Comparing long-read assemblers to explore the potential of a sustainable low-cost, low-infrastructure approach to sequence antimicrobial resistant bacteria with Oxford nanopore sequencing. Frontiers in Microbiology 13 796465. (10.3389/fmicb.2022.796465)
2021
- Boostrom, I. et al. 2021. Evaluation of the MYCOPLASMA IST3 urogenital mycoplasma assay in an international multicentre trial. Journal of Antimicrobial Chemotherapy 76 (12), pp.3175-3182. (10.1093/jac/dkab320)
- Sharratt, M. et al. 2021. Defining fluoroquinolone resistance-mediating mutations from non-resistance polymorphisms in Mycoplasma hominis Topoisomerases. Antibiotics 10 (11) 1379. (10.3390/antibiotics10111379)
- Spiller-Boulter, O. et al., 2021. Determination of in vitro antimicrobial susceptibility for Lefamulin (Pleuromutilin) for Ureaplasma Spp. and Mycoplasma hominis. Antibiotics 10 (11) 1370. (10.3390/antibiotics10111370)
2020
- Pasqualetto, G. et al. 2020. Computational studies towards the identification of novel rhodopsin-binding compounds as chemical chaperones for misfolded opsins. Molecules 25 (21) 4904. (10.3390/molecules25214904)
- Farzana, R. et al. 2020. Molecular and epidemiological analysis of a Burkholderia cepacia sepsis outbreak from a tertiary care hospital in Bangladesh. PLoS Neglected Tropical Diseases 14 (4) e0008200. (10.1371/journal.pntd.0008200)
2019
- Farzana, R. et al. 2019. Emergence of mcr-1 mediated colistin resistant Escherichia coli from a hospitalized patient in Bangladesh. Journal of Infection in Developing Countries 13 (08), pp.773-776. (10.3855/jidc.11541)
Articles
- Saud, Z. et al. 2026. Discovery of a fungal Tc toxin complex and functional mycoserpin through a novel two-by-two comparative genomics approach. Frontiers in Cellular and Infection Microbiology 16 1800461. (10.3389/fcimb.2026.1800461)
- Sands, K. et al. 2025. Acquisition of Escherichia coli carrying extended-spectrum ß-lactamase and carbapenemase genes by hospitalised children with severe acute malnutrition in Niger. Nature Communications 16 (1) 6751. (10.1038/s41467-025-61718-w)
- Nieto-Rosado, M. et al. 2024. Colonisation of hospital surfaces from low- and middle-income countries by extended spectrum β-lactamase- and carbapenemase-producing bacteria. Nature Communications 15 2758. (10.1038/s41467-024-46684-z)
- Portal, E. A. R. et al. 2024. Characterisation of colistin resistance in Gram-negative microbiota of pregnant women and neonates in Nigeria. Nature Communications 15 (1) 2302. (10.1038/s41467-024-45673-6)
- Farzana, R. et al. 2023. Genomic insights into the mechanism of carbapenem resistance dissemination in Enterobacterales from a tertiary public heath setting in South Asia. Clinical Infectious Diseases 76 (1), pp.119-133. (10.1093/cid/ciac287)
- Carvalho, M. J. et al., 2022. Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low- and middle-income countries. Nature Microbiology 7 , pp.1337-1347. (10.1038/s41564-022-01184-y)
- Acolatse, J. E. E. et al., 2022. Environmental surveillance of ESBL and carbapenemase-producing gram-negative bacteria in a Ghanaian Tertiary Hospital. Antimicrobial Resistance and Infection Control 11 (1) 49. (10.1186/s13756-022-01090-2)
- Boostrom, I. et al. 2022. Comparing long-read assemblers to explore the potential of a sustainable low-cost, low-infrastructure approach to sequence antimicrobial resistant bacteria with Oxford nanopore sequencing. Frontiers in Microbiology 13 796465. (10.3389/fmicb.2022.796465)
- Boostrom, I. et al. 2021. Evaluation of the MYCOPLASMA IST3 urogenital mycoplasma assay in an international multicentre trial. Journal of Antimicrobial Chemotherapy 76 (12), pp.3175-3182. (10.1093/jac/dkab320)
- Sharratt, M. et al. 2021. Defining fluoroquinolone resistance-mediating mutations from non-resistance polymorphisms in Mycoplasma hominis Topoisomerases. Antibiotics 10 (11) 1379. (10.3390/antibiotics10111379)
- Spiller-Boulter, O. et al., 2021. Determination of in vitro antimicrobial susceptibility for Lefamulin (Pleuromutilin) for Ureaplasma Spp. and Mycoplasma hominis. Antibiotics 10 (11) 1370. (10.3390/antibiotics10111370)
- Pasqualetto, G. et al. 2020. Computational studies towards the identification of novel rhodopsin-binding compounds as chemical chaperones for misfolded opsins. Molecules 25 (21) 4904. (10.3390/molecules25214904)
- Farzana, R. et al. 2020. Molecular and epidemiological analysis of a Burkholderia cepacia sepsis outbreak from a tertiary care hospital in Bangladesh. PLoS Neglected Tropical Diseases 14 (4) e0008200. (10.1371/journal.pntd.0008200)
- Farzana, R. et al. 2019. Emergence of mcr-1 mediated colistin resistant Escherichia coli from a hospitalized patient in Bangladesh. Journal of Infection in Developing Countries 13 (08), pp.773-776. (10.3855/jidc.11541)